BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|12965172 taste receptor, type 2, member 9 [Homo sapiens] (312 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|12965172 taste receptor, type 2, member 9 [Homo sapiens] 617 e-177 gi|12965176 taste receptor, type 2, member 7 [Homo sapiens] 306 1e-83 gi|12965174 taste receptor, type 2, member 8 [Homo sapiens] 275 5e-74 gi|8394398 taste receptor T2R3 [Homo sapiens] 235 4e-62 gi|12965180 taste receptor, type 2, member 10 [Homo sapiens] 226 2e-59 gi|12965178 taste receptor, type 2, member 13 [Homo sapiens] 211 7e-55 gi|154937355 taste receptor, type 2, member 20 [Homo sapiens] 205 5e-53 gi|117414133 taste receptor, type 2, member 46 [Homo sapiens] 204 1e-52 gi|148235367 type 2 taste receptor member 30 [Homo sapiens] 202 3e-52 gi|116235454 taste receptor, type 2, member 31 [Homo sapiens] 195 5e-50 gi|28882035 taste receptor, type 2, member 19 [Homo sapiens] 195 5e-50 gi|116235464 taste receptor, type 2, member 43 [Homo sapiens] 190 2e-48 gi|154937357 taste receptor, type 2, member 50 [Homo sapiens] 182 3e-46 gi|29126245 taste receptor, type 2, member 45 [Homo sapiens] 182 4e-46 gi|31088852 taste receptor, type 2, member 42 [Homo sapiens] 168 5e-42 gi|12965182 taste receptor, type 2, member 14 [Homo sapiens] 168 6e-42 gi|28882033 taste receptor, type 2, member 40 [Homo sapiens] 159 3e-39 gi|116268093 taste receptor, type 2, member 41 [Homo sapiens] 155 3e-38 gi|116875819 taste receptor, type 2, member 39 [Homo sapiens] 145 6e-35 gi|9625043 taste receptor T2R1 [Homo sapiens] 140 1e-33 gi|9507173 taste receptor T2R5 [Homo sapiens] 140 2e-33 gi|28973795 taste receptor, type 2, member 60 [Homo sapiens] 134 8e-32 gi|223278415 taste receptor, type 2, member 38 [Homo sapiens] 132 4e-31 gi|8394402 taste receptor T2R4 [Homo sapiens] 113 2e-25 gi|8394395 taste receptor T2R16 [Homo sapiens] 111 9e-25 gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] 49 6e-06 gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] 49 6e-06 gi|14043062 angiotensin II receptor, type 1 [Homo sapiens] 49 6e-06 gi|6715583 angiotensin II receptor, type 1 [Homo sapiens] 49 6e-06 gi|4501997 angiotensin II receptor, type 1 [Homo sapiens] 49 6e-06 >gi|12965172 taste receptor, type 2, member 9 [Homo sapiens] Length = 312 Score = 617 bits (1592), Expect = e-177 Identities = 312/312 (100%), Positives = 312/312 (100%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC Sbjct: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF Sbjct: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 Query: 121 WLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQ 180 WLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQ Sbjct: 121 WLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQ 180 Query: 181 LTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLL 240 LTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLL Sbjct: 181 LTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLL 240 Query: 241 LIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFV 300 LIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFV Sbjct: 241 LIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFV 300 Query: 301 KCFLRRRKPFVP 312 KCFLRRRKPFVP Sbjct: 301 KCFLRRRKPFVP 312 >gi|12965176 taste receptor, type 2, member 7 [Homo sapiens] Length = 318 Score = 306 bits (785), Expect = 1e-83 Identities = 150/311 (48%), Positives = 214/311 (68%), Gaps = 3/311 (0%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M ++ + L GE ++GI GN FI LVNC+DW+K+R I+ ID+IL SLAISRICLLC Sbjct: 1 MADKVQTTLLFLAVGEFSVGILGNAFIGLVNCMDWVKKRKIASIDLILTSLAISRICLLC 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 VI LD F ++L+P Y + I++ WT N+ S+WF +CLSI+Y KI N HP F Sbjct: 61 VILLDCFILVLYPDVYATGKEMRIIDFFWTLTNHLSIWFATCLSIYYFFKIGNFFHPLFL 120 Query: 121 WLKLKINKVMLAILLGSFLISLIISVPKNDDM---WYHLFKVSHEENITWKFKVSKIPGT 177 W+K +I++V+ ILLG ++S+ IS+P +++ + K + N+TW +V+K Sbjct: 121 WMKWRIDRVISWILLGCVVLSVFISLPATENLNADFRFCVKAKRKTNLTWSCRVNKTQHA 180 Query: 178 FKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIF 237 +L LNL ++PF +CL+SFFLL+ SL RH ++++L ATG RDPSTEAH+RA+KAVI F Sbjct: 181 STKLFLNLATLLPFCVCLMSFFLLILSLRRHIRRMQLSATGCRDPSTEAHVRALKAVISF 240 Query: 238 LLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 LLL I YY FL+ TSS +P+ +L ++ G+ + +I+PSSHSFILI+GN+KLR A LK++ Sbjct: 241 LLLFIAYYLSFLIATSSYFMPETELAVIFGESIALIYPSSHSFILILGNNKLRHASLKVI 300 Query: 298 RFVKCFLRRRK 308 V L+ RK Sbjct: 301 WKVMSILKGRK 311 >gi|12965174 taste receptor, type 2, member 8 [Homo sapiens] Length = 309 Score = 275 bits (702), Expect = 5e-74 Identities = 150/311 (48%), Positives = 209/311 (67%), Gaps = 9/311 (2%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M S + I+IILI GE +GI GNG+I LVN IDW+K++ IS +D IL +L I+RICL+ Sbjct: 1 MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYILTNLVIARICLIS 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 V+ ++G ++L P Y + ++ WTFAN ++W T+CL++FY LKIA+ SHP F Sbjct: 61 VMVVNGIVIVLNPDVYTKNKQQIVIFTFWTFANYLNMWITTCLNVFYFLKIASSSHPLFL 120 Query: 121 WLKLKINKVMLAILLGSFLISLIIS----VPKNDDMWYHLFKVSHEENITWKFKVSKIPG 176 WLK KI+ V+ ILLG F ISL++S + + D +H H+ NIT F VSKIP Sbjct: 121 WLKWKIDMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHAI-AKHKRNITEMFHVSKIP- 178 Query: 177 TFKQLTL-NLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVI 235 F+ LTL NL +VPFI+ LISFFLL+ SL RHTKQI+L+ATG RDPSTE H+RAIK + Sbjct: 179 YFEPLTLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMT 238 Query: 236 IFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLK 295 F+ +YY ++MT S L+ + KL + G+I +++P HS ILI+ N+KLR+ F++ Sbjct: 239 SFIFFFFLYYISSILMTFSYLMTKYKLAVEFGEIAAILYPLGHSLILIVLNNKLRQTFVR 298 Query: 296 ML--RFVKCFL 304 ML R + C + Sbjct: 299 MLTCRKIACMI 309 >gi|8394398 taste receptor T2R3 [Homo sapiens] Length = 316 Score = 235 bits (599), Expect = 4e-62 Identities = 118/300 (39%), Positives = 188/300 (62%), Gaps = 2/300 (0%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M E +++IL + T+GI N FI LVN W K + +SL D I+ +LA+ RI LLC Sbjct: 1 MMGLTEGVFLILSGTQFTLGILVNCFIELVNGSSWFKTKRMSLSDFIITTLALLRIILLC 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 +I D F + P T+ + +++ I++V WTF N+ S+W +CL + Y LKIA+ SHP F Sbjct: 61 IILTDSFLIEFSPNTHDSGIIMQIIDVSWTFTNHLSIWLATCLGVLYCLKIASFSHPTFL 120 Query: 121 WLKLKINKVMLAILLGSFLISLIISVPK-NDDMWYHLFK-VSHEENITWKFKVSKIPGTF 178 WLK ++++VM+ +LLG+ L+S + N+ Y +F+ + N+T F+ + Sbjct: 121 WLKWRVSRVMVWMLLGALLLSCGSTASLINEFKLYSVFRGIEATRNVTEHFRKKRSEYYL 180 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 + L + P I+ L S+ LL+FSL RHT+Q+ + T RDP+TEAH RAI+ ++ F Sbjct: 181 IHVLGTLWYLPPLIVSLASYSLLIFSLGRHTRQMLQNGTSSRDPTTEAHKRAIRIILSFF 240 Query: 239 LLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLR 298 L ++Y+ FL+ + +P+ K+ MIG+++T+ +P+ HSFILI+GNSKL++ F+ MLR Sbjct: 241 FLFLLYFLAFLIASFGNFLPKTKMAKMIGEVMTMFYPAGHSFILILGNSKLKQTFVVMLR 300 >gi|12965180 taste receptor, type 2, member 10 [Homo sapiens] Length = 307 Score = 226 bits (577), Expect = 2e-59 Identities = 126/311 (40%), Positives = 184/311 (59%), Gaps = 13/311 (4%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M +E I+I ++ E G+ GNGFI LVNCID K + +S I IL LAISRI L+ Sbjct: 1 MLRVVEGIFIFVVVSESVFGVLGNGFIGLVNCIDCAKNK-LSTIGFILTGLAISRIFLIW 59 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 +I DGF + P Y + L+ ++ W N SS+WF + LSIFY LKIAN S+ F Sbjct: 60 IIITDGFIQIFSPNIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIANFSNYIFL 119 Query: 121 WLKLKINKVM----LAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPG 176 WLK + N V+ + +L+ S L I+ ND +K ++ W + K Sbjct: 120 WLKSRTNMVLPFMIVFLLISSLLNFAYIAKILND------YKTKNDT--VWDLNMYKSEY 171 Query: 177 TFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVII 236 KQ+ LNLGV+ F L LI+ L+ SL RH +Q++ + TG RD +TEAH++A+K +I Sbjct: 172 FIKQILLNLGVIFFFTLSLITCIFLIISLWRHNRQMQSNVTGLRDSNTEAHVKAMKVLIS 231 Query: 237 FLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKM 296 F++L I+Y+ + S + + KL+LM G T I+P HSFILI+GNSKL++A L++ Sbjct: 232 FIILFILYFIGMAIEISCFTVRENKLLLMFGMTTTAIYPWGHSFILILGNSKLKQASLRV 291 Query: 297 LRFVKCFLRRR 307 L+ +KC +R+ Sbjct: 292 LQQLKCCEKRK 302 >gi|12965178 taste receptor, type 2, member 13 [Homo sapiens] Length = 303 Score = 211 bits (537), Expect = 7e-55 Identities = 121/299 (40%), Positives = 181/299 (60%), Gaps = 11/299 (3%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M SA+ +I+ ++I E IG NGFIVL+NCIDW+ +R++S +D +LI LAISRI L+ Sbjct: 1 MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 I + F L + + + + I+ W +N+ +LW + SIFYLLKIA+ S P F Sbjct: 61 EILVSWFLALHYLAIFVSGTGLRIMIFSWIVSNHFNLWLATIFSIFYLLKIASFSSPAFL 120 Query: 121 WLKLKINKVMLAILLGS--FLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTF 178 +LK ++NKV+L ILLG+ FL +I + + W +E N TW F +S TF Sbjct: 121 YLKWRVNKVILMILLGTLVFLFLNLIQINMHIKDWLD----RYERNTTWNFSMSDFE-TF 175 Query: 179 K---QLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVI 235 + T+ + + PF + ISF LL+FSL +H ++++L+ G RDP T+ H A+K VI Sbjct: 176 SVSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHRDPRTKVHTNALKIVI 235 Query: 236 IFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFL 294 FLL ++ L+ S L Q ++ M+ + + V PSSHSF+LI+GN+KLR+AFL Sbjct: 236 SFLLFYASFFLCVLISWISELY-QNTVIYMLCETIGVFSPSSHSFLLILGNAKLRQAFL 293 >gi|154937355 taste receptor, type 2, member 20 [Homo sapiens] Length = 309 Score = 205 bits (521), Expect = 5e-53 Identities = 116/312 (37%), Positives = 179/312 (57%), Gaps = 3/312 (0%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M S + ++ IL+ +G + NGFI L+N I W+KR+ IS D I+ +LA+SR+ LL Sbjct: 1 MMSFLHIVFSILVVVAFILGNFANGFIALINFIAWVKRQKISSADQIIAALAVSRVGLLW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 VI L + +L P + V++ I N W N+ S+W + LSIFYLLKI N S F Sbjct: 61 VILLHWYSTVLNPTSSNLKVIIFISNA-WAVTNHFSIWLATSLSIFYLLKIVNFSRLIFH 119 Query: 121 WLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQ 180 LK K V+L I+LGS + V K+ + +++ E N+TWK K+ Sbjct: 120 HLKRKAKSVVLVIVLGSLFFLVCHLVMKHT--YINVWTEECEGNVTWKIKLRNAMHLSNL 177 Query: 181 LTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLL 240 L ++PF L LISF LL++SL +H K+++LH G +DPST+ H++A++ V FL+L Sbjct: 178 TVAMLANLIPFTLTLISFLLLIYSLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLIL 237 Query: 241 LIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFV 300 L +Y+ ++ + + ++VLM+ +I+PS HSFILI GN L++ FL +L V Sbjct: 238 LAIYFLCLIISFWNFKMRPKEIVLMLCQAFGIIYPSFHSFILIWGNKTLKQTFLSVLWQV 297 Query: 301 KCFLRRRKPFVP 312 C+ + + P Sbjct: 298 TCWAKGQNQSTP 309 >gi|117414133 taste receptor, type 2, member 46 [Homo sapiens] Length = 309 Score = 204 bits (518), Expect = 1e-52 Identities = 121/311 (38%), Positives = 176/311 (56%), Gaps = 7/311 (2%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M + + I+ ILI IG + NGFI LVN I+W KR+ IS D IL +LA+SR+ LL Sbjct: 1 MITFLPIIFSILIVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 V+ L+ + L P V ++ NV W N+ S W + LSIFYLLKIAN S+ F Sbjct: 61 VLVLNWYATELNPAFNSIEVRITAYNV-WAVINHFSNWLATSLSIFYLLKIANFSNLIFL 119 Query: 121 WLKLKINKVMLAILLGS--FLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTF 178 LK ++ V+L ILLG FL+ + + N +W +E N+TWK K+ Sbjct: 120 HLKRRVKSVVLVILLGPLLFLVCHLFVINMNQIIWTK----EYEGNMTWKIKLRSAMYLS 175 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 L +VPF L LISF LL+ SL +H K+++LH G +DPS + H++A++ V FL Sbjct: 176 NTTVTILANLVPFTLTLISFLLLICSLCKHLKKMQLHGKGSQDPSMKVHIKALQTVTSFL 235 Query: 239 LLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLR 298 LL +Y+ ++ S + K V M + + +PS+H FILI GN KL++ FL +L Sbjct: 236 LLCAIYFLSIIMSVWSFESLENKPVFMFCEAIAFSYPSTHPFILIWGNKKLKQTFLSVLW 295 Query: 299 FVKCFLRRRKP 309 V+ +++ KP Sbjct: 296 HVRYWVKGEKP 306 >gi|148235367 type 2 taste receptor member 30 [Homo sapiens] Length = 319 Score = 202 bits (514), Expect = 3e-52 Identities = 116/309 (37%), Positives = 178/309 (57%), Gaps = 7/309 (2%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M + + I+ ILI IG + NGFI LVN I+W+KR+ IS +D IL +LA+SR+ LL Sbjct: 1 MITFLPIIFSILIVVIFVIGNFANGFIALVNSIEWVKRQKISFVDQILTALAVSRVGLLW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 V+ L + L P Y V ++ N VW N+ S W + LS+FYLL+IAN S+ F Sbjct: 61 VLLLHWYATQLNPAFYSVEVRITAYN-VWAVTNHFSSWLATSLSMFYLLRIANFSNLIFL 119 Query: 121 WLKLKINKVMLAILLGS--FLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTF 178 +K ++ V+L ILLG FL+ + + ++ +W +E N+TWK K+ Sbjct: 120 RIKRRVKSVVLVILLGPLLFLVCHLFVINMDETVW----TKEYEGNVTWKIKLRSAMYHS 175 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 L VP L LISF LL+ SL +H K+++LH G +DPST+ H++A++ V FL Sbjct: 176 NMTLTMLANFVPLTLTLISFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVTSFL 235 Query: 239 LLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLR 298 LL +Y+ ++ + + + V M + +PS+H FILI+GN KL++ FL +LR Sbjct: 236 LLCAIYFLSMIISVCNFGRLEKQPVFMFCQAIIFSYPSTHPFILILGNKKLKQIFLSVLR 295 Query: 299 FVKCFLRRR 307 V+ +++ R Sbjct: 296 HVRYWVKDR 304 >gi|116235454 taste receptor, type 2, member 31 [Homo sapiens] Length = 309 Score = 195 bits (495), Expect = 5e-50 Identities = 119/312 (38%), Positives = 172/312 (55%), Gaps = 3/312 (0%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M + I I+ ++ IG + NGFI LVN I+ +KR+ IS D IL +LA+SR+ LL Sbjct: 1 MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 V+ L+ + + P Y V + NV W + S W + LSIFYLLKIAN S+ F Sbjct: 61 VLLLNWYSTVFNPAFYSVEVRTTAYNV-WAVTGHFSNWLATSLSIFYLLKIANFSNLIFL 119 Query: 121 WLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQ 180 LK ++ V+L +LLG L N M + +E N+TWK K+ Sbjct: 120 HLKRRVKSVILVMLLGPLLFLACQLFVIN--MKEIVRTKEYEGNLTWKIKLRSAVYLSDA 177 Query: 181 LTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLL 240 LG +VPF L L+ F LL+ SL +H K+++LH G +DPST+ H++A++ VI FLLL Sbjct: 178 TVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLL 237 Query: 241 LIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFV 300 VY+ ++ S + K V M + +PS H FILI GN KL++ FL +LR V Sbjct: 238 CAVYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQV 297 Query: 301 KCFLRRRKPFVP 312 + +++ KP P Sbjct: 298 RYWVKGEKPSSP 309 >gi|28882035 taste receptor, type 2, member 19 [Homo sapiens] Length = 299 Score = 195 bits (495), Expect = 5e-50 Identities = 113/289 (39%), Positives = 164/289 (56%), Gaps = 7/289 (2%) Query: 11 ILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFML 70 IL+ +G NGFI LVN IDW+ R IS + IL +L +SRI LL V+ + + Sbjct: 11 ILVVFAFVLGNVANGFIALVNVIDWVNTRKISSAEQILTALVVSRIGLLWVMLFLWYATV 70 Query: 71 LFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVM 130 YG V + N W N+ S+W + LSIF LLKIAN S+ LK +I V+ Sbjct: 71 FNSALYGLEVRIVASNA-WAVTNHFSMWLAASLSIFCLLKIANFSNLISLHLKKRIKSVV 129 Query: 131 LAILLGS--FLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQLTLNLGVM 188 L ILLG FLI + + ++ +W +E N+TWK K+ L + Sbjct: 130 LVILLGPLVFLICNLAVITMDERVWTK----EYEGNVTWKIKLRNAIHLSSLTVTTLANL 185 Query: 189 VPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYPVF 248 +PF L LI F LL+ SL +H K++RLH+ G +DPST+ H++A++ V FL+L +Y+ Sbjct: 186 IPFTLSLICFLLLICSLCKHLKKMRLHSKGSQDPSTKVHIKALQTVTSFLMLFAIYFLCI 245 Query: 249 LVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 + T + Q KLVL++ V +++PS HSFILIMG+ KL++ FL +L Sbjct: 246 ITSTWNLRTQQSKLVLLLCQTVAIMYPSFHSFILIMGSRKLKQTFLSVL 294 >gi|116235464 taste receptor, type 2, member 43 [Homo sapiens] Length = 309 Score = 190 bits (482), Expect = 2e-48 Identities = 118/315 (37%), Positives = 178/315 (56%), Gaps = 9/315 (2%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M + + I+ L+ IG + NGFI LVN I+W KR+ IS D IL +LA+SR+ LL Sbjct: 1 MITFLPIIFSSLVVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 V+ L+ + +L P V + N+ W N+ S W + LSIFYLLKIAN S+ F Sbjct: 61 VLLLNWYSTVLNPAFNSVEVRTTAYNI-WAVINHFSNWLATTLSIFYLLKIANFSNFIFL 119 Query: 121 WLKLKINKVMLAILLGS--FLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTF 178 LK ++ V+L +LLG FL + + N+ + F E N+TWK K+ K F Sbjct: 120 HLKRRVKSVILVMLLGPLLFLACHLFVINMNEIVRTKEF----EGNMTWKIKL-KSAMYF 174 Query: 179 KQLTLNLGV-MVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIF 237 +T+ + +VPF L L+SF LL+ SL +H K+++LH G +DPST+ H++A++ VI F Sbjct: 175 SNMTVTMVANLVPFTLTLLSFMLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVISF 234 Query: 238 LLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 LLL +Y+ ++ S + K V M + +PS H FILI GN KL++ FL + Sbjct: 235 LLLCAIYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVF 294 Query: 298 RFVKCFLRRRKPFVP 312 ++ +++ K P Sbjct: 295 WQMRYWVKGEKTSSP 309 >gi|154937357 taste receptor, type 2, member 50 [Homo sapiens] Length = 299 Score = 182 bits (462), Expect = 3e-46 Identities = 110/296 (37%), Positives = 167/296 (56%), Gaps = 7/296 (2%) Query: 9 YIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFF 68 + ILI +G + NGFI LVN IDW+KR+ IS D IL +LA+SRI LL + L+ + Sbjct: 9 FSILIMVLFVLGNFANGFIALVNFIDWVKRKKISSADQILTALAVSRIGLLWALLLNWYL 68 Query: 69 MLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINK 128 +L P Y + ++ N W N+ S+W + LSIFYLLKIAN S+ F LK ++ Sbjct: 69 TVLNPAFYSVELRITSYNA-WVVTNHFSMWLAANLSIFYLLKIANFSNLLFLHLKRRVRS 127 Query: 129 VMLAILLGS--FLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQLTLNLG 186 V+L ILLG+ FL+ ++ ++ MW +E N+T K K+ L Sbjct: 128 VILVILLGTLIFLVCHLLVANMDESMWAE----EYEGNMTGKMKLRNTVHLSYLTVTTLW 183 Query: 187 VMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYP 246 +PF L LISF +L+ SL +H K+++LH G +D ST+ H++A++ +I FLLL +++ Sbjct: 184 SFIPFTLSLISFLMLICSLCKHLKKMQLHGEGSQDLSTKVHIKALQTLISFLLLCAIFFL 243 Query: 247 VFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVKC 302 +V S + V+M+ V I+ + SFILI KL+ FL +L ++C Sbjct: 244 FLIVSVWSPRRLRNDPVVMVSKAVGNIYLAFDSFILIWRTKKLKHTFLLILCQIRC 299 >gi|29126245 taste receptor, type 2, member 45 [Homo sapiens] Length = 299 Score = 182 bits (461), Expect = 4e-46 Identities = 109/299 (36%), Positives = 165/299 (55%), Gaps = 7/299 (2%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M + + I+ IL+ IG + NGFI LVN +W+KR+ IS D I+ +LA+SR+ LL Sbjct: 1 MITFLPIIFSILVVVTFVIGNFANGFIALVNSTEWVKRQKISFADQIVTALAVSRVGLLW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 V+ L+ + +L P + + N+ W + S W + LSIFYLLKIAN S+ F Sbjct: 61 VLLLNWYSTVLNPAFCSVELRTTAYNI-WAVTGHFSNWPATSLSIFYLLKIANFSNLIFL 119 Query: 121 WLKLKINKVMLAILLGS--FLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTF 178 LK ++ V+L +LLG FL + V N +W +E N+TWK K+ + Sbjct: 120 RLKRRVKSVILVVLLGPLLFLACHLFVVNMNQIVWTK----EYEGNMTWKIKLRRAMYLS 175 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 L +VPF + LISF LL+ SL +H K+++LH G +DPST+ H++ ++ VI F Sbjct: 176 DTTVTMLANLVPFTVTLISFLLLVCSLCKHLKKMQLHGKGSQDPSTKVHIKVLQTVISFF 235 Query: 239 LLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 LL +Y+ ++ S + K V M + S+H FILI GN KL++ +L +L Sbjct: 236 LLRAIYFVSVIISVWSFKNLENKPVFMFCQAIGFSCSSAHPFILIWGNKKLKQTYLSVL 294 >gi|31088852 taste receptor, type 2, member 42 [Homo sapiens] Length = 314 Score = 168 bits (426), Expect = 5e-42 Identities = 107/304 (35%), Positives = 161/304 (52%), Gaps = 12/304 (3%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M + ++ I++IL E I + GN FI LVNC + +K + + D IL LAIS I L Sbjct: 1 MATELDKIFLILAIAEFIISMLGNVFIGLVNCSEGIKNQKVFSADFILTCLAISTIGQLL 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 VI D F + L Y L V ++W N+ + W +CLSIFY KIA+ H F Sbjct: 61 VILFDSFLVGLASHLYTTYRLGKTVIMLWHMTNHLTTWLATCLSIFYFFKIAHFPHSLFL 120 Query: 121 WLKLKIN-KVMLAILLGSFLI---SLIISVPKNDDMWYHLFKVSHEENITWKFKVSKI-- 174 WL+ ++N +++ ++L FL+ SL++ + + + + + N+T SK Sbjct: 121 WLRWRMNGMIVMLLILSLFLLIFDSLVLEIFIDISL-----NIIDKSNLTLYLDESKTLY 175 Query: 175 -PGTFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKA 233 + + L+L +PF L L S L SLVRHT+ ++L + G RD STEAH RA+K Sbjct: 176 DKLSILKTLLSLTSFIPFSLFLTSLLFLFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKM 235 Query: 234 VIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAF 293 V+ FL L IV++ V + + + FPS HSFILI+GNSKLR+ Sbjct: 236 VMSFLFLFIVHFFSLQVANGIFFMLWNNKYIKFVMLALNAFPSCHSFILILGNSKLRQTA 295 Query: 294 LKML 297 +++L Sbjct: 296 VRLL 299 >gi|12965182 taste receptor, type 2, member 14 [Homo sapiens] Length = 317 Score = 168 bits (425), Expect = 6e-42 Identities = 106/314 (33%), Positives = 173/314 (55%), Gaps = 12/314 (3%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M I++I+ ++ E IG GN FI LVNCIDW+K R IS +D IL +LAISRI L+ Sbjct: 1 MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 +I + FP + + ++ +WT N+ S+W + L FY LKIAN S+ F Sbjct: 61 LIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFL 120 Query: 121 WLKLKINKVMLAILLGS----FLISLIISVPKNDDM-WYHLFKVSHEENITWKFKVSKIP 175 +LK ++ KV+L +LL + FL +I++ N + Y K ++ + S I Sbjct: 121 YLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLI- 179 Query: 176 GTFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVI 235 LT + + +PF L L F LL+FS+ +H K+++ D ST+AH R +K+VI Sbjct: 180 ----VLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAH-RGVKSVI 234 Query: 236 IFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLK 295 F LL ++ F + ++ + L++ + ++ + +PS HS +LI+GN KLR+A L Sbjct: 235 TFFLLYAIFSLSFFISVWTSERLEENLII-LSQVMGMAYPSCHSCVLILGNKKLRQASLS 293 Query: 296 MLRFVKCFLRRRKP 309 +L +++ + +P Sbjct: 294 VLLWLRYMFKDGEP 307 >gi|28882033 taste receptor, type 2, member 40 [Homo sapiens] Length = 323 Score = 159 bits (402), Expect = 3e-39 Identities = 101/307 (32%), Positives = 165/307 (53%), Gaps = 5/307 (1%) Query: 3 SAIEAIYIILIAG-ELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCV 61 S + + ++++G E GI G+GFI + +W + + + D I++ L+ SR+ L Sbjct: 14 SKFKVTFTLVVSGIECITGILGSGFITAIYGAEWARGKTLPTGDRIMLMLSFSRLLLQIW 73 Query: 62 ISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFW 121 + L+ F LLF Y + + + V+ F N+S+LWF + L +FY L+IAN +HP FF Sbjct: 74 MMLENIFSLLFRIVYNQNSVYILFKVITVFLNHSNLWFAAWLKVFYCLRIANFNHPLFFL 133 Query: 122 LKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVS---HEENITWKFKVSKIPGTF 178 +K KI +M +L S L+SL S P + D++ S N T K S+ Sbjct: 134 MKRKIIVLMPWLLRLSVLVSLSFSFPLSRDVFNVYVNSSIPIPSSNSTEKKYFSETNMVN 193 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 N+G+ VP I+ +++ LL+ SL RHT + +ATG RDPS +AH+ AIKA FL Sbjct: 194 LVFFYNMGIFVPLIMFILAATLLILSLKRHTLHMGSNATGSRDPSMKAHIGAIKATSYFL 253 Query: 239 LLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLR 298 +L I + + L +++S + ++ I+ +P+ HS LI+GN LR A+ + Sbjct: 254 ILYI-FNAIALFLSTSNIFDTYSSWNILCKIIMAAYPAGHSVQLILGNPGLRRAWKRFQH 312 Query: 299 FVKCFLR 305 V +L+ Sbjct: 313 QVPLYLK 319 >gi|116268093 taste receptor, type 2, member 41 [Homo sapiens] Length = 307 Score = 155 bits (393), Expect = 3e-38 Identities = 108/312 (34%), Positives = 165/312 (52%), Gaps = 17/312 (5%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M +A+ A +++L + +GI NGFIVLV +WL+ + +D+ILISL SR CL Sbjct: 1 MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQL 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 V ++ F+ Y + ++ W F N+++ WF S LS+ + +KIANI+H F Sbjct: 61 VGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFL 120 Query: 121 WLKLKINKVMLAILLGSFLISLIISVP---KNDDMWYHLFKVSHEENITWKFKVSKIPGT 177 WLK + + +LLGS LIS II++ N ++ N+T+K+ Sbjct: 121 WLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRIETYY 180 Query: 178 FKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIF 237 F L L + +PF + L+S LL+ SL RHT++++ + +DPST+AH RA+K++I F Sbjct: 181 FPSLKLVIW-SIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISF 239 Query: 238 LLLLIVYYPVFLVMTSSALIPQGKLVLMIGD------IVTVIFPSSHSFILIMGNSKLRE 291 L+L Y FL S +I K + M D I + S H FILI N KLR Sbjct: 240 LIL---YALSFL----SLIIDAAKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRS 292 Query: 292 AFLKMLRFVKCF 303 F ++L + F Sbjct: 293 VFSQLLLLARGF 304 >gi|116875819 taste receptor, type 2, member 39 [Homo sapiens] Length = 338 Score = 145 bits (365), Expect = 6e-35 Identities = 102/303 (33%), Positives = 156/303 (51%), Gaps = 16/303 (5%) Query: 2 PSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCV 61 P I I +L+A E IGI NGFI+ ++ +W++ + +S IL+ L++SRI L + Sbjct: 31 PFLITLILAVLLA-EYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLSVSRIALQSL 89 Query: 62 ISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFW 121 + L+ Y + + + F N SLWF + LS FY +KIAN S+P F Sbjct: 90 MMLEITISSTSLSFYSEDAVYYAFKISFIFLNFCSLWFAAWLSFFYFVKIANFSYPLFLK 149 Query: 122 LKLKINKVMLAILLGSFLISL--------IISVPKNDDMWYHLFKVSHEENITWKFKVSK 173 L+ +I ++ +L S IS I +V N+ F + H N T K +S+ Sbjct: 150 LRWRITGLIPWLLWLSVFISFSHSMFCINICTVYCNNS-----FPI-HSSNSTKKTYLSE 203 Query: 174 IPGTFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKA 233 I NLG++ P I+ +++ LL+ SL RHT + +ATG DPS EAHM AIKA Sbjct: 204 INVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTLHMGSNATGSNDPSMEAHMGAIKA 263 Query: 234 VIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAF 293 + FL+L I + V L + S + L + I+ +P+SHS +LI N LR A+ Sbjct: 264 ISYFLILYI-FNAVALFIYLSNMFDINSLWNNLCQIIMAAYPASHSILLIQDNPGLRRAW 322 Query: 294 LKM 296 ++ Sbjct: 323 KRL 325 >gi|9625043 taste receptor T2R1 [Homo sapiens] Length = 299 Score = 140 bits (353), Expect = 1e-33 Identities = 99/302 (32%), Positives = 157/302 (51%), Gaps = 19/302 (6%) Query: 8 IYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGF 67 IY +L + +GI+ NG IV+VN ID +K R ++ +D++L LA+SRI L I Sbjct: 8 IYFLLAVIQFLLGIFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYVNV 67 Query: 68 FMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKIN 127 ++ F ++ S + F N LW + L +FY K+A++ HP F WLK++I+ Sbjct: 68 IVIFFI----EFIMCSANCAILLFINELELWLATWLGVFYCAKVASVRHPLFIWLKMRIS 123 Query: 128 KVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQLTLNLGV 187 K++ ++LGS L +I V + Y F V + KF S+ K+ TL + + Sbjct: 124 KLVPWMILGSLLYVSMICVFHSK---YAGFMVPY---FLRKF-FSQNATIQKEDTLAIQI 176 Query: 188 M-------VPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLL 240 VP ++ L + LL+FSL RHT+Q+R G R P A + A+ +++ FL+L Sbjct: 177 FSFVAEFSVPLLIFLFAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAPISALLSILSFLIL 236 Query: 241 LIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFV 300 + + V SS + + + +V I+PS HS ILI+GN KL++ K L Sbjct: 237 YFSHC-MIKVFLSSLKFHIRRFIFLFFILVIGIYPSGHSLILILGNPKLKQNAKKFLLHS 295 Query: 301 KC 302 KC Sbjct: 296 KC 297 >gi|9507173 taste receptor T2R5 [Homo sapiens] Length = 299 Score = 140 bits (352), Expect = 2e-33 Identities = 93/305 (30%), Positives = 164/305 (53%), Gaps = 10/305 (3%) Query: 1 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLC 60 M SA + +++ E IG+ GNG +V+ + +W+++ + S ++I++ LA R L Sbjct: 1 MLSAGLGLLMLVAVVEFLIGLIGNGSLVVWSFREWIRKFNWSSYNLIILGLAGCRFLLQW 60 Query: 61 VISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFF 120 +I LD + LFP + +S + +++ W + +SLWF + LS+FY KI P + Sbjct: 61 LIILD---LSLFP-LFQSSRWLRYLSIFWVLVSQASLWFATFLSVFYCKKITTFDRPAYL 116 Query: 121 WLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQ 180 WLK + + L LLG F+I+L+++V + +YH +I + F+ + F+ Sbjct: 117 WLKQRAYNLSLWCLLGYFIINLLLTV-QIGLTFYH--PPQGNSSIRYPFESWQYLYAFQ- 172 Query: 181 LTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLL 240 LN G +P ++ L+S +L+ SL H K++++H+ G RD +AH+ A+K++ FLLL Sbjct: 173 --LNSGSYLPLVVFLVSSGMLIVSLYTHHKKMKVHSAGRRDVRAKAHITALKSLGCFLLL 230 Query: 241 LIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFV 300 +VY +S P + I + + +PS HS ILIMG ++++ K+L Sbjct: 231 HLVYIMASPFSITSKTYPPDLTSVFIWETLMAAYPSLHSLILIMGIPRVKQTCQKILWKT 290 Query: 301 KCFLR 305 C R Sbjct: 291 VCARR 295 >gi|28973795 taste receptor, type 2, member 60 [Homo sapiens] Length = 318 Score = 134 bits (338), Expect = 8e-32 Identities = 93/294 (31%), Positives = 154/294 (52%), Gaps = 18/294 (6%) Query: 19 IGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFMLLFPGTYGN 78 + I GNGFI ++W+ RR + D +L+SL SR CL V+ ++ L P + Sbjct: 30 VAIAGNGFITAALGVEWVLRRMLLPCDKLLVSLGASRFCLQSVVMGKTIYVFLHPMAFPY 89 Query: 79 SVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKIN---KVMLAILL 135 + ++ + W F N ++LW ++ LS+FY +KIA +HP FFWLK K++ ML + Sbjct: 90 NPVLQFLAFQWDFLNAATLWSSTWLSVFYCVKIATFTHPVFFWLKHKLSGWLPWMLFSSV 149 Query: 136 GSFLISLIISVPKNDDMWY-----HL--FKVSHEENITWKFKVSKIPGTFKQLTLNLGVM 188 G + I+ N M+ HL + V+ + ++ K P K +T + Sbjct: 150 GLSSFTTILFFIGNHRMYQNYLRNHLQPWNVTGDSIRSYCEKFYLFP--LKMITWTMPTA 207 Query: 189 VPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYPVF 248 V F +C+I LL+ SL RH K+ L +GFR+PS +AH++A+ A++ F +L I Y+ + Sbjct: 208 V-FFICMI---LLITSLGRHRKKALLTTSGFREPSVQAHIKALLALLSFAMLFISYF-LS 262 Query: 249 LVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVKC 302 LV +++ + P + + V + + H IL+ N +LR A LK R +C Sbjct: 263 LVFSAAGIFPPLDFKFWVWESVIYLCAAVHPIILLFSNCRLR-AVLKSRRSSRC 315 >gi|223278415 taste receptor, type 2, member 38 [Homo sapiens] Length = 333 Score = 132 bits (332), Expect = 4e-31 Identities = 87/322 (27%), Positives = 162/322 (50%), Gaps = 32/322 (9%) Query: 5 IEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICL-----L 59 + + ++ + E +G N F+ LVN D +KR+ +S D +L+ L+ISR+ L L Sbjct: 14 VRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCLSISRLFLHGLLFL 73 Query: 60 CVISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFF 119 I L F L P + ++ ++W AN ++LW +CLS+ Y K+ SH F Sbjct: 74 SAIQLTHFQKLSEPLNHSYQAII----MLWMIANQANLWLAACLSLLYCSKLIRFSHTFL 129 Query: 120 F----WLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFK----------VSHEENI 165 W+ KI++++L I+L S + +++ +W + +++ + Sbjct: 130 ICLASWVSRKISQMLLGIILCSCICTVLC-------VWCFFSRPHFTVTTVLFMNNNTRL 182 Query: 166 TWKFKVSKIPGTFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTE 225 W+ K + +F L L + PF+L L+S +L SL RH + ++++ RDPS E Sbjct: 183 NWQIKDLNLFYSF--LFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLE 240 Query: 226 AHMRAIKAVIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMG 285 AH++A+K+++ F ++ + ++ + K+ +M+ + PS H+ ILI G Sbjct: 241 AHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISG 300 Query: 286 NSKLREAFLKMLRFVKCFLRRR 307 N+KLR A + +L + + L+ R Sbjct: 301 NAKLRRAVMTILLWAQSSLKVR 322 >gi|8394402 taste receptor T2R4 [Homo sapiens] Length = 299 Score = 113 bits (283), Expect = 2e-25 Identities = 90/289 (31%), Positives = 146/289 (50%), Gaps = 14/289 (4%) Query: 19 IGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFMLLFPGTYGN 78 +GI N FI +VNC W+K IS D IL SL I+R +L + ++ + + T + Sbjct: 19 VGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVS-SNTERS 77 Query: 79 SVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVMLAILLGSF 138 L + + + F ++SS+WF + L+I Y +KI N H F LK I+ + +LL Sbjct: 78 VYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACV 137 Query: 139 LISLIISVPKNDDMWYHLFKVS-HEENITWK----FKVSKIPGTFKQL-TLNLGVMVPFI 192 LIS + ++ L + S E +T + F +S+ G + +L L + FI Sbjct: 138 LISAFTTC-----LYITLSQASPFPELVTTRNNTSFNISE--GILSLVVSLVLSSSLQFI 190 Query: 193 LCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYPVFLVMT 252 + + S LL+ SL RH ++++ +ATGF +P TEAH+ A+K ++ FL+L I Y LV Sbjct: 191 INVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQY 250 Query: 253 SSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVK 301 I I ++ HS ++I+ + KL+ K+L F K Sbjct: 251 LPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK 299 >gi|8394395 taste receptor T2R16 [Homo sapiens] Length = 291 Score = 111 bits (277), Expect = 9e-25 Identities = 80/284 (28%), Positives = 142/284 (50%), Gaps = 14/284 (4%) Query: 10 IILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFM 69 II + LTI I + IV V +WL+ R + +D+ILISL ISR CL L+ F Sbjct: 12 IIYVLESLTI-IVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFC- 69 Query: 70 LLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKV 129 + + ++ + + W F N + W S L++FY +K+++ +H F WL+ +I ++ Sbjct: 70 ----SYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWRILRL 125 Query: 130 MLAILLGSFLISLIISVPK--NDDMWYHLFKVSH-EENITWKFKVSKIPGTFKQLTLNLG 186 ILLGS +I+ + +P + + L + H N T K+ ++ + Sbjct: 126 FPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENF-HQYQFQAHTVA 184 Query: 187 VMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYP 246 +++PFIL L S L+ SL TKQI+ H+TG +PS +A A++++ + ++ Y+ Sbjct: 185 LVIPFILFLASTIFLMASL---TKQIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYFL 241 Query: 247 VFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLR 290 L+ L + + L + + F HS L++ + L+ Sbjct: 242 TILITIIGTLFDK-RCWLWVWEAFVYAFILMHSTSLMLSSPTLK 284 >gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 48.9 bits (115), Expect = 6e-06 Identities = 70/317 (22%), Positives = 139/317 (43%), Gaps = 34/317 (10%) Query: 5 IEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISL 64 I +Y I+ +GI+GN +V+V ++K + ++ + L++LA++ +C L + L Sbjct: 31 IPTLYSIIFV----VGIFGNSLVVIV-IYFYMKLKTVA--SVFLLNLALADLCFLLTLPL 83 Query: 65 DGFFMLL-FPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLK 123 + + + +GN L I + +F +S++ +CLSI L I HP +K Sbjct: 84 WAVYTAMEYRWPFGN-YLCKIASASVSFNLYASVFLLTCLSIDRYLAIV---HP----MK 135 Query: 124 LKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENIT-----WKFKVSKIPGTF 178 ++ + ML + +I L+ + + + NIT ++ + S +P Sbjct: 136 SRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL 195 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 LG + PF++ L S + L++ ++ +I+ + P + + I A+++F Sbjct: 196 GLTKNILGFLFPFLIILTS-YTLIWKALKKAYEIQKN-----KPRNDDIFKIIMAIVLFF 249 Query: 239 LLLIVYYPVFLVMTSSALIPQGKL-VLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 + + +F + LI G + I DIV P + + N+ L F L Sbjct: 250 FFSWIPHQIFTFL--DVLIQLGIIRDCRIADIVDTAMPI--TICIAYFNNCLNPLFYGFL 305 Query: 298 --RFVKCFLRRRKPFVP 312 +F + FL+ K P Sbjct: 306 GKKFKRYFLQLLKYIPP 322 >gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 48.9 bits (115), Expect = 6e-06 Identities = 70/317 (22%), Positives = 139/317 (43%), Gaps = 34/317 (10%) Query: 5 IEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISL 64 I +Y I+ +GI+GN +V+V ++K + ++ + L++LA++ +C L + L Sbjct: 31 IPTLYSIIFV----VGIFGNSLVVIV-IYFYMKLKTVA--SVFLLNLALADLCFLLTLPL 83 Query: 65 DGFFMLL-FPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLK 123 + + + +GN L I + +F +S++ +CLSI L I HP +K Sbjct: 84 WAVYTAMEYRWPFGN-YLCKIASASVSFNLYASVFLLTCLSIDRYLAIV---HP----MK 135 Query: 124 LKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENIT-----WKFKVSKIPGTF 178 ++ + ML + +I L+ + + + NIT ++ + S +P Sbjct: 136 SRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL 195 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 LG + PF++ L S + L++ ++ +I+ + P + + I A+++F Sbjct: 196 GLTKNILGFLFPFLIILTS-YTLIWKALKKAYEIQKN-----KPRNDDIFKIIMAIVLFF 249 Query: 239 LLLIVYYPVFLVMTSSALIPQGKL-VLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 + + +F + LI G + I DIV P + + N+ L F L Sbjct: 250 FFSWIPHQIFTFL--DVLIQLGIIRDCRIADIVDTAMPI--TICIAYFNNCLNPLFYGFL 305 Query: 298 --RFVKCFLRRRKPFVP 312 +F + FL+ K P Sbjct: 306 GKKFKRYFLQLLKYIPP 322 >gi|14043062 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 48.9 bits (115), Expect = 6e-06 Identities = 70/317 (22%), Positives = 139/317 (43%), Gaps = 34/317 (10%) Query: 5 IEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISL 64 I +Y I+ +GI+GN +V+V ++K + ++ + L++LA++ +C L + L Sbjct: 31 IPTLYSIIFV----VGIFGNSLVVIV-IYFYMKLKTVA--SVFLLNLALADLCFLLTLPL 83 Query: 65 DGFFMLL-FPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLK 123 + + + +GN L I + +F +S++ +CLSI L I HP +K Sbjct: 84 WAVYTAMEYRWPFGN-YLCKIASASVSFNLYASVFLLTCLSIDRYLAIV---HP----MK 135 Query: 124 LKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENIT-----WKFKVSKIPGTF 178 ++ + ML + +I L+ + + + NIT ++ + S +P Sbjct: 136 SRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL 195 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 LG + PF++ L S + L++ ++ +I+ + P + + I A+++F Sbjct: 196 GLTKNILGFLFPFLIILTS-YTLIWKALKKAYEIQKN-----KPRNDDIFKIIMAIVLFF 249 Query: 239 LLLIVYYPVFLVMTSSALIPQGKL-VLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 + + +F + LI G + I DIV P + + N+ L F L Sbjct: 250 FFSWIPHQIFTFL--DVLIQLGIIRDCRIADIVDTAMPI--TICIAYFNNCLNPLFYGFL 305 Query: 298 --RFVKCFLRRRKPFVP 312 +F + FL+ K P Sbjct: 306 GKKFKRYFLQLLKYIPP 322 >gi|6715583 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 48.9 bits (115), Expect = 6e-06 Identities = 70/317 (22%), Positives = 139/317 (43%), Gaps = 34/317 (10%) Query: 5 IEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISL 64 I +Y I+ +GI+GN +V+V ++K + ++ + L++LA++ +C L + L Sbjct: 31 IPTLYSIIFV----VGIFGNSLVVIV-IYFYMKLKTVA--SVFLLNLALADLCFLLTLPL 83 Query: 65 DGFFMLL-FPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLK 123 + + + +GN L I + +F +S++ +CLSI L I HP +K Sbjct: 84 WAVYTAMEYRWPFGN-YLCKIASASVSFNLYASVFLLTCLSIDRYLAIV---HP----MK 135 Query: 124 LKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENIT-----WKFKVSKIPGTF 178 ++ + ML + +I L+ + + + NIT ++ + S +P Sbjct: 136 SRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL 195 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 LG + PF++ L S + L++ ++ +I+ + P + + I A+++F Sbjct: 196 GLTKNILGFLFPFLIILTS-YTLIWKALKKAYEIQKN-----KPRNDDIFKIIMAIVLFF 249 Query: 239 LLLIVYYPVFLVMTSSALIPQGKL-VLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 + + +F + LI G + I DIV P + + N+ L F L Sbjct: 250 FFSWIPHQIFTFL--DVLIQLGIIRDCRIADIVDTAMPI--TICIAYFNNCLNPLFYGFL 305 Query: 298 --RFVKCFLRRRKPFVP 312 +F + FL+ K P Sbjct: 306 GKKFKRYFLQLLKYIPP 322 >gi|4501997 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 48.9 bits (115), Expect = 6e-06 Identities = 70/317 (22%), Positives = 139/317 (43%), Gaps = 34/317 (10%) Query: 5 IEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISL 64 I +Y I+ +GI+GN +V+V ++K + ++ + L++LA++ +C L + L Sbjct: 31 IPTLYSIIFV----VGIFGNSLVVIV-IYFYMKLKTVA--SVFLLNLALADLCFLLTLPL 83 Query: 65 DGFFMLL-FPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLK 123 + + + +GN L I + +F +S++ +CLSI L I HP +K Sbjct: 84 WAVYTAMEYRWPFGN-YLCKIASASVSFNLYASVFLLTCLSIDRYLAIV---HP----MK 135 Query: 124 LKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENIT-----WKFKVSKIPGTF 178 ++ + ML + +I L+ + + + NIT ++ + S +P Sbjct: 136 SRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL 195 Query: 179 KQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFL 238 LG + PF++ L S + L++ ++ +I+ + P + + I A+++F Sbjct: 196 GLTKNILGFLFPFLIILTS-YTLIWKALKKAYEIQKN-----KPRNDDIFKIIMAIVLFF 249 Query: 239 LLLIVYYPVFLVMTSSALIPQGKL-VLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKML 297 + + +F + LI G + I DIV P + + N+ L F L Sbjct: 250 FFSWIPHQIFTFL--DVLIQLGIIRDCRIADIVDTAMPI--TICIAYFNNCLNPLFYGFL 305 Query: 298 --RFVKCFLRRRKPFVP 312 +F + FL+ K P Sbjct: 306 GKKFKRYFLQLLKYIPP 322 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.334 0.147 0.458 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,265,823 Number of Sequences: 37866 Number of extensions: 385320 Number of successful extensions: 1744 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 78 Number of HSP's that attempted gapping in prelim test: 1631 Number of HSP's gapped (non-prelim): 128 length of query: 312 length of database: 18,247,518 effective HSP length: 102 effective length of query: 210 effective length of database: 14,385,186 effective search space: 3020889060 effective search space used: 3020889060 T: 11 A: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 39 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.