Search of human proteins with 4504223

Search of human proteins with 4504223

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504223 glucuronidase, beta [Homo sapiens]
         (651 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504223 glucuronidase, beta [Homo sapiens]                        1355   0.0  
gi|239752590 PREDICTED: similar to Beta-glucuronidase [Homo sapi...   173   5e-43
gi|239742570 PREDICTED: hypothetical protein XP_002342556 [Homo ...   118   1e-26
gi|239742560 PREDICTED: hypothetical protein XP_002342555 [Homo ...   118   1e-26
gi|239748531 PREDICTED: similar to hCG1820960 [Homo sapiens]           97   6e-20
gi|239742564 PREDICTED: hypothetical protein XP_002342575 [Homo ...    91   3e-18
gi|239742568 PREDICTED: hypothetical protein XP_002342577 [Homo ...    89   1e-17
gi|84798622 mannosidase, beta A, lysosomal [Homo sapiens]              49   1e-05
gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap...    33   1.1  
gi|29570798 phosphoribosyl pyrophosphate amidotransferase propro...    30   7.0  
gi|4758896 peroxisomal biogenesis factor 14 [Homo sapiens]             30   9.1  

>gi|4504223 glucuronidase, beta [Homo sapiens]
          Length = 651

 Score = 1355 bits (3506), Expect = 0.0
 Identities = 651/651 (100%), Positives = 651/651 (100%)

Query: 1   MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFE 60
           MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFE
Sbjct: 1   MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFE 60

Query: 61  EQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVV 120
           EQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVV
Sbjct: 61  EQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVV 120

Query: 121 LRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTT 180
           LRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTT
Sbjct: 121 LRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTT 180

Query: 181 LPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQD 240
           LPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQD
Sbjct: 181 LPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQD 240

Query: 241 SGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYL 300
           SGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYL
Sbjct: 241 SGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYL 300

Query: 301 YSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKG 360
           YSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKG
Sbjct: 301 YSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKG 360

Query: 361 FDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNN 420
           FDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNN
Sbjct: 361 FDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNN 420

Query: 421 VSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVT 480
           VSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVT
Sbjct: 421 VSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVT 480

Query: 481 FVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSE 540
           FVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSE
Sbjct: 481 FVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSE 540

Query: 541 YGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTR 600
           YGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTR
Sbjct: 541 YGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTR 600

Query: 601 VLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSPFT 651
           VLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSPFT
Sbjct: 601 VLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSPFT 651


>gi|239752590 PREDICTED: similar to Beta-glucuronidase [Homo
           sapiens]
          Length = 194

 Score =  173 bits (438), Expect = 5e-43
 Identities = 85/116 (73%), Positives = 94/116 (81%), Gaps = 1/116 (0%)

Query: 27  MLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDI 86
           MLYP+ESPSRE KEL GLWSF AD  DNRR+GF+E+WY RPL ESGPT+D+ VP SFNDI
Sbjct: 1   MLYPKESPSREPKELGGLWSFPADL-DNRRQGFKEKWYPRPLQESGPTLDVLVPFSFNDI 59

Query: 87  SQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLEH 142
            QDWRLRHFV W+ YE EV LPE+WTQDLR RVVLRIGSAHSY IV   G+   EH
Sbjct: 60  GQDWRLRHFVSWMLYEWEVTLPEKWTQDLRARVVLRIGSAHSYDIVVSQGLFCPEH 115


>gi|239742570 PREDICTED: hypothetical protein XP_002342556 [Homo
           sapiens]
          Length = 90

 Score =  118 bits (296), Expect = 1e-26
 Identities = 56/69 (81%), Positives = 61/69 (88%)

Query: 465 MVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQ 524
           MVIAHTK+LDPS+PVTFV+NS YAADKGA YVDVI +NSYYSWY +YGHLELIQLQLA Q
Sbjct: 1   MVIAHTKALDPSQPVTFVTNSTYAADKGALYVDVIRVNSYYSWYRNYGHLELIQLQLAAQ 60

Query: 525 FENWYKKYQ 533
           FENW K  Q
Sbjct: 61  FENWCKTSQ 69


>gi|239742560 PREDICTED: hypothetical protein XP_002342555 [Homo
           sapiens]
          Length = 90

 Score =  118 bits (296), Expect = 1e-26
 Identities = 56/69 (81%), Positives = 61/69 (88%)

Query: 465 MVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQ 524
           MVIAHTK+LDPS+PVTFV+NS YAADKGA YVDVI +NSYYSWY +YGHLELIQLQLA Q
Sbjct: 1   MVIAHTKALDPSQPVTFVTNSTYAADKGALYVDVIRVNSYYSWYRNYGHLELIQLQLAAQ 60

Query: 525 FENWYKKYQ 533
           FENW K  Q
Sbjct: 61  FENWCKTSQ 69


>gi|239748531 PREDICTED: similar to hCG1820960 [Homo sapiens]
          Length = 86

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 44/49 (89%), Positives = 47/49 (95%)

Query: 549 FHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQS 597
           F +DPPLMF+EEYQKSLLEQYHLGL+QKRRKYVVGELIWNFADFMT QS
Sbjct: 12  FEKDPPLMFSEEYQKSLLEQYHLGLNQKRRKYVVGELIWNFADFMTNQS 60


>gi|239742564 PREDICTED: hypothetical protein XP_002342575 [Homo
           sapiens]
          Length = 142

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 42/46 (91%), Positives = 44/46 (95%)

Query: 551 QDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQ 596
           QDPPLMF+EE +KSLLEQYHLGLDQKRRKYVVGELIWNFADFMT Q
Sbjct: 58  QDPPLMFSEEDRKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTNQ 103


>gi|239742568 PREDICTED: hypothetical protein XP_002342577 [Homo
           sapiens]
          Length = 99

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 41/45 (91%), Positives = 43/45 (95%)

Query: 552 DPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQ 596
           DPPLMF+EE +KSLLEQYHLGLDQKRRKYVVGELIWNFADFMT Q
Sbjct: 16  DPPLMFSEEDRKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTNQ 60


>gi|84798622 mannosidase, beta A, lysosomal [Homo sapiens]
          Length = 879

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 75/335 (22%), Positives = 128/335 (38%), Gaps = 57/335 (17%)

Query: 285 VSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQ-----FLIN 339
           V  WWP+    +  Y  ++  +L    ++   +  Y   V +    +  S      F IN
Sbjct: 287 VETWWPHGHGNQTGYNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKIN 346

Query: 340 GKPFYFHGVN--KHEDADIRGKGFDWPLLVK-----DFNLLRWLGANAFRTSHYPYAEEV 392
           G P +  G N    +    R       LL++     + N LR  G   +        +E 
Sbjct: 347 GFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQ------DEF 400

Query: 393 MQMCDRYGIVVIDECPGVGLALPQ---FFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVA 449
            ++CD  GI+V  +        P    F ++V+     Q+     +R K+HP++++WS  
Sbjct: 401 YELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQI-----KRLKSHPSIIIWSGN 455

Query: 450 NEPASHLESAGYYLKM----------VIAHTKSL-------DPSRPVTFVSNSNYAADKG 492
           NE    L    Y++            V  + K++       D SRP    S +N A    
Sbjct: 456 NENEEALMMNWYHISFTDRPIYIKDYVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVA 515

Query: 493 APYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGFHQD 552
             +V     ++Y+   H Y ++        +   NW K + K    SEYG ++   F   
Sbjct: 516 EAWVSQNPNSNYFGDVHFYDYI--------SDCWNW-KVFPKARFASEYGYQSWPSFSTL 566

Query: 553 PPLMFTEEY----QKSLLEQYHLGLDQKRRKYVVG 583
             +  TE++    + SL  Q+H G   K+  Y  G
Sbjct: 567 EKVSSTEDWSFNSKFSLHRQHHEG-GNKQMLYQAG 600


>gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sapiens]
          Length = 1064

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 17/126 (13%)

Query: 154  SNLVQVGPLPSRLRITIAINNTLTPTTLP---PGTIQYLTDTSKYPKGYFVQNTYFDFFN 210
            S+++   P+PS   IT    NT +P+TL    P TI   T TS+        +T  D   
Sbjct: 904  SSILSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTD--- 960

Query: 211  YAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLDAENKVV 270
                       TT TTY   IT T S E         +  KG ++      L+   N+  
Sbjct: 961  ----------STTETTYSTSITGTLSTEISLPATTSSLITKGISMTSTR-NLVTTTNENT 1009

Query: 271  ANGTGT 276
            ++ T T
Sbjct: 1010 SHSTPT 1015


>gi|29570798 phosphoribosyl pyrophosphate amidotransferase
           proprotein [Homo sapiens]
          Length = 517

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 487 YAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQF 525
           YA   G PYV+V+C N Y        ++ L QL +A +F
Sbjct: 335 YAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKF 373


>gi|4758896 peroxisomal biogenesis factor 14 [Homo sapiens]
          Length = 377

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 14/32 (43%), Positives = 18/32 (56%)

Query: 506 SWYHDYGHLELIQLQLATQFENWYKKYQKPII 537
           S + DYG L +I   +A  F   YKKY  P+I
Sbjct: 104 SRWRDYGALAIIMAGIAFGFHQLYKKYLLPLI 135


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,376,513
Number of Sequences: 37866
Number of extensions: 1211718
Number of successful extensions: 2210
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2199
Number of HSP's gapped (non-prelim): 11
length of query: 651
length of database: 18,247,518
effective HSP length: 109
effective length of query: 542
effective length of database: 14,120,124
effective search space: 7653107208
effective search space used: 7653107208
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.