Guide to the Human Genome
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Search of human proteins with 4504173

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
         (222 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]           444   e-125
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]         258   4e-69
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]          254   5e-68
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]          253   1e-67
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]          248   3e-66
gi|113417526 PREDICTED: similar to glutathione S-transferase alp...   157   5e-39
gi|169169045 PREDICTED: similar to glutathione S-transferase alp...   156   2e-38
gi|113418092 PREDICTED: similar to glutathione S-transferase alp...   156   2e-38
gi|4504183 glutathione transferase [Homo sapiens]                      79   3e-15
gi|7657457 prostaglandin-D synthase [Homo sapiens]                     59   3e-09
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]     48   6e-06
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]     47   1e-05
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]    45   4e-05
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi...    45   6e-05
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]    43   2e-04
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]              43   2e-04
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]    42   3e-04
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]    42   3e-04
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]    38   0.006
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]              37   0.018
gi|4503481 eukaryotic translation elongation factor 1 gamma [Hom...    33   0.15 
gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo sapi...    29   3.7  
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                    29   3.7  
gi|15529996 son of sevenless homolog 1 [Homo sapiens]                  28   6.2  
gi|62241046 exocyst complex component 7 isoform 1 [Homo sapiens]       28   8.2  
gi|62241044 exocyst complex component 7 isoform 2 [Homo sapiens]       28   8.2  
gi|223718053 exocyst complex component 7 isoform 6 [Homo sapiens]      28   8.2  
gi|223718050 exocyst complex component 7 isoform 5 [Homo sapiens]      28   8.2  
gi|223718046 exocyst complex component 7 isoform 4 [Homo sapiens]      28   8.2  
gi|223718041 exocyst complex component 7 isoform 3 [Homo sapiens]      28   8.2  

>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
          Length = 222

 Score =  444 bits (1141), Expect = e-125
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
           MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
Sbjct: 1   MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60

Query: 61  DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
           DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
Sbjct: 61  DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120

Query: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
           VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180

Query: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP 222
           LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP 222


>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
          Length = 222

 Score =  258 bits (658), Expect = 4e-69
 Identities = 120/221 (54%), Positives = 173/221 (78%)

Query: 1   MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
           MA +PKLHY N RGRMES+RW+LAAAGVEF+E+F+++ E L KL++  +L+FQQVPMVEI
Sbjct: 1   MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60

Query: 61  DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
           DGMKLVQTR+IL+YIA K+NL+GK++KE+ LIDMY+EG  DL E++++ PF +P++Q  +
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120

Query: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
           +  + +K   RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ +  +EE   +++S+FP 
Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180

Query: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
           L+    ++SN+PT+K+FL+PGS +KPP DE  +     IFR
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221


>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
          Length = 222

 Score =  254 bits (648), Expect = 5e-68
 Identities = 119/221 (53%), Positives = 170/221 (76%)

Query: 1   MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
           MA +PKLHY N RGRMES RW+LAAAGVEF+E+F+++ E L KL++  +L+FQQVPMVEI
Sbjct: 1   MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60

Query: 61  DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
           DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY+EG  DL E++++ P   P+++  +
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120

Query: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
           +  + +K   RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ +  +EE   +++S+FP 
Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180

Query: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
           L+    ++SN+PT+K+FL+PGS +KPP DE  +     IFR
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFR 221


>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
          Length = 222

 Score =  253 bits (645), Expect = 1e-67
 Identities = 118/221 (53%), Positives = 167/221 (75%)

Query: 1   MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
           MA +PKLHY NGRGRME +RW+LAAAGVEF+E+F+ + E L KL++   L+FQQVPMVEI
Sbjct: 1   MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60

Query: 61  DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
           DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY EG  DL E++++ P  +P+++  +
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120

Query: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
           +  + +K   RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ +  +EE   +++S FP 
Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180

Query: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
           L+    ++SN+PT+K+FL+PGS +KPP D   +     IFR
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221


>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
          Length = 222

 Score =  248 bits (633), Expect = 3e-66
 Identities = 118/221 (53%), Positives = 166/221 (75%)

Query: 1   MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
           MA +PKLHY N RG MES+RW+LAAAGVE +E+FLE+ E L KL++   LLFQQVPMVEI
Sbjct: 1   MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60

Query: 61  DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
           DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY EG +DL E++++    +P+++  +
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120

Query: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
              + +K   RYFP FEK+L+ H Q +LVGN+LS AD+ L++    +EE   +++S+FP 
Sbjct: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180

Query: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
           L+    ++SN+PT+K+FL+PGS++KPP DE  +     IFR
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFR 221


>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 216

 Score =  157 bits (398), Expect = 5e-39
 Identities = 84/210 (40%), Positives = 131/210 (62%), Gaps = 16/210 (7%)

Query: 28  VEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLK 87
           VE + +FLE+ + L KL++    +FQQVPMVEIDGMKLVQTR+IL+YIA K+NL GK++K
Sbjct: 6   VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIK 65

Query: 88  ERT---------LIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEK 138
           ER           +DMY+EG   L E L+      P+++  ++  + +     YFPVFE 
Sbjct: 66  ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125

Query: 139 ILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF-------LQEYTVKLSNI 191
           +L+ H Q + +GN+LS AD+ L++ +  +EE   +++S FP        L+   +++S +
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185

Query: 192 PTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
           PT+K+FL+PGS +K P D   ++    IF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215


>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 227

 Score =  156 bits (394), Expect = 2e-38
 Identities = 83/209 (39%), Positives = 130/209 (62%), Gaps = 16/209 (7%)

Query: 29  EFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKE 88
           E + +FLE+ + L KL++    +FQQVPMVEIDGMKLVQTR+IL+YI  K+NL GK++KE
Sbjct: 18  ESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKE 77

Query: 89  RT---------LIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKI 139
           R           +DMY+EG   L E L+      P+++  ++  + +     YFPVFE +
Sbjct: 78  RAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETV 137

Query: 140 LRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF-------LQEYTVKLSNIP 192
           L+ H Q +L+GN+LS AD+ L++ +  +EE   +++S FP        L+   +++S +P
Sbjct: 138 LKSHEQDYLIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLP 197

Query: 193 TIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
           T+K+FL+PGS +K P D   ++    IF+
Sbjct: 198 TVKKFLQPGSLRKLPIDAKGLQEATKIFK 226


>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 216

 Score =  156 bits (394), Expect = 2e-38
 Identities = 83/210 (39%), Positives = 130/210 (61%), Gaps = 16/210 (7%)

Query: 28  VEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLK 87
           VE + +FLE+ + L KL++    +FQQVPMVEIDGMKLVQTR+IL+YI  K+NL GK++K
Sbjct: 6   VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIK 65

Query: 88  ERT---------LIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEK 138
           ER           +DMY+EG   L E L+      P+++  ++  + +     YFPVFE 
Sbjct: 66  ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125

Query: 139 ILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF-------LQEYTVKLSNI 191
           +L+ H Q + +GN+LS AD+ L++ +  +EE   +++S FP        L+   +++S +
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185

Query: 192 PTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
           PT+K+FL+PGS +K P D   ++    IF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215


>gi|4504183 glutathione transferase [Homo sapiens]
          Length = 210

 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 60/191 (31%), Positives = 96/191 (50%), Gaps = 13/191 (6%)

Query: 13  RGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGN---HLLFQQVPMVEIDGMKLVQTR 69
           RGR  ++R +LA  G  + EE +  +      Q+G+     L+ Q+P  +   + L Q+ 
Sbjct: 12  RGRCAALRMLLADQGQSWKEEVVTVETW----QEGSLKASCLYGQLPKFQDGDLTLYQSN 67

Query: 70  SILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAI 129
           +IL ++     L+GK+ +E  L+DM  +G  DL    I   +   +  + + V    KA+
Sbjct: 68  TILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYV----KAL 123

Query: 130 IRYFPVFEKILRGH--GQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVK 187
                 FE +L  +  G++F+VG+Q+S AD  LL  +L  E   P  L AFP L  Y  +
Sbjct: 124 PGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGR 183

Query: 188 LSNIPTIKRFL 198
           LS  P +K FL
Sbjct: 184 LSARPKLKAFL 194


>gi|7657457 prostaglandin-D synthase [Homo sapiens]
          Length = 199

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 51/199 (25%), Positives = 98/199 (49%), Gaps = 16/199 (8%)

Query: 6   KLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKL 65
           KL Y N RGR E +R++ A   +++++  +E  +     +  + L F ++P++E+DG+ L
Sbjct: 5   KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWP---EIKSTLPFGKIPILEVDGLTL 61

Query: 66  VQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMA 125
            Q+ +I  Y+    +L G    E+  +D  V+ TLD  + +   P+ +     KE   M 
Sbjct: 62  HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLD--DFMSCFPWAEKKQDVKE--QMF 116

Query: 126 QKAIIRYFPVFEKILRGH--GQSFLVGNQLSLADV---ILLQTILALEEKIPNILSAFPF 180
            + +    P   + L  +  G+ +L+GN ++ AD    I   T+L  +   P++L   P 
Sbjct: 117 NELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFK---PDLLDNHPR 173

Query: 181 LQEYTVKLSNIPTIKRFLE 199
           L     K+  IP +  +++
Sbjct: 174 LVTLRKKVQAIPAVANWIK 192


>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
          Length = 218

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 54/216 (25%), Positives = 98/216 (45%), Gaps = 27/216 (12%)

Query: 7   LHYPNGRGRMESVRWVLAAAGVEFDEEFLET-------KEQLYKLQDGNHLLFQQVPMVE 59
           L Y N RG   S+R +L      ++E+           + Q    +    L F  +P + 
Sbjct: 5   LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63

Query: 60  IDGM-KLVQTRSILHYIADKHNLFGKNLKER----TLIDMYVEGTLDLLELLIMHPF--L 112
           IDG  K+ Q+ +IL YIA KHNL G++ KE+     L + +++  + L +L     F  L
Sbjct: 64  IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKL 123

Query: 113 KPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIP 172
           KP+  Q         A+     ++ + L    Q + +G++++  D I    +   +   P
Sbjct: 124 KPEYLQ---------ALPEMLKLYSQFL--GKQPWFLGDKITFVDFIAYDVLERNQVFEP 172

Query: 173 NILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPP 208
           + L AFP L+++  +   +  I  +++  S+  P P
Sbjct: 173 SCLDAFPNLKDFISRFEGLEKISAYMK-SSRFLPRP 207


>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
          Length = 218

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/179 (25%), Positives = 77/179 (43%), Gaps = 40/179 (22%)

Query: 52  FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPF 111
           F  +P +     K+ Q+ +IL YIA KHNL G+  +E+  +D+                 
Sbjct: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDIL---------------- 100

Query: 112 LKPDDQQKEVVNMAQKAIIRYFPVFEKI----------LRGHGQSFL------VGNQLSL 155
              ++Q  +V N  Q A + Y P FEK+          +  H   FL      VG++++ 
Sbjct: 101 ---ENQAMDVSN--QLARVCYSPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITF 155

Query: 156 ADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVR 214
            D +    +       PN L AFP L+++  +   +  I  +++  S+  P P  +Y R
Sbjct: 156 VDFLAYDVLDLHRIFEPNCLDAFPNLKDFISRFEGLEKISAYMK-SSRFLPKP--LYTR 211


>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
          Length = 218

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 39/173 (22%), Positives = 70/173 (40%), Gaps = 38/173 (21%)

Query: 52  FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPF 111
           F  +P +     K+ Q+ +IL YIA KHNL G+  +E+  +D+    T+D          
Sbjct: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD---------- 106

Query: 112 LKPDDQQKEVVNMAQKAIIRYFPVFEKILRGH----------------GQSFLVGNQLSL 155
                      N  Q  +I Y P FEK+   +                 + +  GN+++ 
Sbjct: 107 -----------NHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITF 155

Query: 156 ADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPP 208
            D ++   +       P  L AFP L+++  +   +  I  +++  S+  P P
Sbjct: 156 VDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMK-SSRFLPRP 207


>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
           sapiens]
          Length = 191

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 50/192 (26%), Positives = 88/192 (45%), Gaps = 26/192 (13%)

Query: 7   LHYPNGRGRMESVRWVLAAAGVEFDEEFLET-------KEQLYKLQDGNHLLFQQVPMVE 59
           L Y N RG   S+R +L      ++E+           + Q    +    L F  +P + 
Sbjct: 5   LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63

Query: 60  IDGM-KLVQTRSILHYIADKHNLFGKNLKER----TLIDMYVEGTLDLLELLIMHPF--L 112
           IDG  K+ Q+ +IL YIA KHNL G++ KE+     L + +++  + L +L     F  L
Sbjct: 64  IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKL 123

Query: 113 KPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIP 172
           KP+  Q         A+     ++ + L    Q + +G++++  D I    +   +   P
Sbjct: 124 KPEYLQ---------ALPEMLKLYSQFL--GKQPWFLGDKITFVDFIAYDVLERNQVFEP 172

Query: 173 NILSAFPFLQEY 184
           + L AFP L+++
Sbjct: 173 SCLDAFPNLKDF 184


>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
          Length = 195

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 37/149 (24%)

Query: 52  FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPF 111
           F  +P +     K+ Q+ +IL YIA KHNL G+  +E+  +D+                 
Sbjct: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDIL---------------- 100

Query: 112 LKPDDQQKEVVNMAQKAIIRYFPVFEKI----------LRGHGQSFL------VGNQLSL 155
              ++Q  +V N  Q A + Y P FEK+          +  H   FL      VG++++ 
Sbjct: 101 ---ENQAMDVSN--QLARVCYSPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITF 155

Query: 156 ADVILLQTILALEEKIPNILSAFPFLQEY 184
            D +    +       PN L AFP L+++
Sbjct: 156 VDFLAYDVLDLHRIFEPNCLDAFPNLKDF 184


>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
          Length = 225

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 49/214 (22%), Positives = 83/214 (38%), Gaps = 24/214 (11%)

Query: 7   LHYPNGRGRMESVRWVLAAAGVEFDEEFLETKE-------QLYKLQDGNHLLFQQVPMVE 59
           L Y + RG   ++R +L      ++E+     E       Q   ++    L F  +P + 
Sbjct: 9   LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68

Query: 60  IDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIM------HPFLK 113
               K+ Q+ +IL YIA KHN+ G+  +E+  +D+     +D    LI       H  LK
Sbjct: 69  DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLK 128

Query: 114 PDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPN 173
           P  Q  E +    K    +   F         S+  G +L+  D +    +       P 
Sbjct: 129 P--QYLEELPGQLKQFSMFLGKF---------SWFAGEKLTFVDFLTYDILDQNRIFDPK 177

Query: 174 ILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPP 207
            L  FP L+ +  +   +  I  +L+     K P
Sbjct: 178 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMP 211


>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
          Length = 161

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 34/139 (24%), Positives = 71/139 (51%), Gaps = 5/139 (3%)

Query: 53  QQVPMVEIDGMKLVQTRSILHYIADKH---NLFGKNLKERTLIDMYVEGTLDLLELLIMH 109
           +QVP ++IDG+ + Q+ +I+ Y+ +      L  ++ K+R  + M  +     ++ L   
Sbjct: 2   KQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNL 61

Query: 110 PFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEE 169
             LK   ++ ++   AQ AI   F   E+IL+     + VG+++++AD+ L+  + A  E
Sbjct: 62  SVLKQVGEEMQLT-WAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQV-ANAE 119

Query: 170 KIPNILSAFPFLQEYTVKL 188
           +    L+ +P +     +L
Sbjct: 120 RFKVDLTPYPTISSINKRL 138


>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
          Length = 216

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 34/139 (24%), Positives = 71/139 (51%), Gaps = 5/139 (3%)

Query: 53  QQVPMVEIDGMKLVQTRSILHYIADKH---NLFGKNLKERTLIDMYVEGTLDLLELLIMH 109
           +QVP ++IDG+ + Q+ +I+ Y+ +      L  ++ K+R  + M  +     ++ L   
Sbjct: 57  KQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNL 116

Query: 110 PFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEE 169
             LK   ++ ++   AQ AI   F   E+IL+     + VG+++++AD+ L+  + A  E
Sbjct: 117 SVLKQVGEEMQLT-WAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQV-ANAE 174

Query: 170 KIPNILSAFPFLQEYTVKL 188
           +    L+ +P +     +L
Sbjct: 175 RFKVDLTPYPTISSINKRL 193


>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
          Length = 181

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 21/88 (23%)

Query: 52  FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPF 111
           F  +P +     K+ Q+ +IL YIA KHNL G+  +E+  +D+    T+D          
Sbjct: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD---------- 106

Query: 112 LKPDDQQKEVVNMAQKAIIRYFPVFEKI 139
                      N  Q  +I Y P FEK+
Sbjct: 107 -----------NHMQLGMICYNPEFEKL 123


>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
          Length = 218

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 33/154 (21%), Positives = 70/154 (45%), Gaps = 17/154 (11%)

Query: 52  FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDM----YVEGTLDLLELLI 107
           F  +P +     K+ Q+ +IL YIA KHNL G+  +E+  +D+     ++  ++L+ L  
Sbjct: 57  FPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCY 116

Query: 108 MHPF--LKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTIL 165
              F  LKP    K +  + +K       ++ + L    + +  G++++  D +    + 
Sbjct: 117 DPDFEKLKP----KYLEELPEK-----LKLYSEFL--GKRPWFAGDKITFVDFLAYDVLD 165

Query: 166 ALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLE 199
                 P  L AF  L+++  +   +  I  +++
Sbjct: 166 MKRIFEPKCLDAFLNLKDFISRFEGLKKISAYMK 199


>gi|4503481 eukaryotic translation elongation factor 1 gamma [Homo
           sapiens]
          Length = 437

 Score = 33.5 bits (75), Expect = 0.15
 Identities = 21/82 (25%), Positives = 44/82 (53%), Gaps = 4/82 (4%)

Query: 119 KEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKI--PNILS 176
           K+    A++ + R   + +  L+   ++FLVG +++LAD+ ++ T+L L +++  P+   
Sbjct: 125 KQATENAKEEVRRILGLLDAYLKT--RTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQ 182

Query: 177 AFPFLQEYTVKLSNIPTIKRFL 198
           AFP    + +   N P  +  L
Sbjct: 183 AFPNTNRWFLTCINQPQFRAVL 204


>gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo
           sapiens]
          Length = 174

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%)

Query: 125 AQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEY 184
           AQ AI   F   E+IL+     + VG+++++AD+ L+  + A  E+    L+ +P +   
Sbjct: 89  AQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQV-ANAERFKVDLTPYPTISSI 147

Query: 185 TVKL 188
             +L
Sbjct: 148 NKRL 151


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 20/164 (12%)

Query: 55  VPMVEIDGMKLVQTRSIL----HYIADKHNLFGKNLKERTLIDMY-VEGTLDLLELLIMH 109
           V +  +  MKL +  S+L    H+++   N+  KN +  TL+ M    G  +++ L++ H
Sbjct: 185 VDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGVTLLHMACASGYKEVVSLILEH 244

Query: 110 --PFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVG-NQLSLADV-------- 158
                  DDQ    +++A K       + + +L       LV  N+   +D+        
Sbjct: 245 GGDLNIVDDQYWTPLHLAAK--YGQTNLVKLLLMHQANPHLVNCNEEKASDIAASEFIEE 302

Query: 159 ILLQTILALEEKIPNILSAFPFLQE--YTVKLSNIPTIKRFLEP 200
           +LL+  +A EEK+   LSA    QE  Y   + ++P +   L P
Sbjct: 303 MLLKAEIAWEEKMKEPLSASTLAQEEPYEEIIHDLPVLSSKLSP 346


>gi|15529996 son of sevenless homolog 1 [Homo sapiens]
          Length = 1333

 Score = 28.1 bits (61), Expect = 6.2
 Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 16/135 (11%)

Query: 58  VEIDGMKLV--QTRSILHYIADKHNLFGKNLKERTLIDMYVEGT--LDLLELLIMHPFLK 113
           +  D +KLV    R+I HY   K ++      ++ L+DM+ +    +++L L    P   
Sbjct: 137 ISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTS 196

Query: 114 PDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPN 173
            +    ++V      I +Y      I++   + F+  ++L  A+             + N
Sbjct: 197 GEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN------------DVEN 244

Query: 174 ILSAFPFLQEYTVKL 188
           I S    + E +VKL
Sbjct: 245 IFSRIVDIHELSVKL 259


>gi|62241046 exocyst complex component 7 isoform 1 [Homo sapiens]
          Length = 684

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 87  KERTLIDMYVEGTLDLLELL--IMHPFLKPDDQQKEVVNMAQKAIIR 131
           KER +I    +G  D LE L  I   +  PD +Q++ +  AQK I++
Sbjct: 596 KERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVK 642


>gi|62241044 exocyst complex component 7 isoform 2 [Homo sapiens]
          Length = 653

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 87  KERTLIDMYVEGTLDLLELL--IMHPFLKPDDQQKEVVNMAQKAIIR 131
           KER +I    +G  D LE L  I   +  PD +Q++ +  AQK I++
Sbjct: 565 KERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVK 611


>gi|223718053 exocyst complex component 7 isoform 6 [Homo sapiens]
          Length = 707

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 87  KERTLIDMYVEGTLDLLELL--IMHPFLKPDDQQKEVVNMAQKAIIR 131
           KER +I    +G  D LE L  I   +  PD +Q++ +  AQK I++
Sbjct: 619 KERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVK 665


>gi|223718050 exocyst complex component 7 isoform 5 [Homo sapiens]
          Length = 676

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 87  KERTLIDMYVEGTLDLLELL--IMHPFLKPDDQQKEVVNMAQKAIIR 131
           KER +I    +G  D LE L  I   +  PD +Q++ +  AQK I++
Sbjct: 588 KERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVK 634


>gi|223718046 exocyst complex component 7 isoform 4 [Homo sapiens]
          Length = 735

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 87  KERTLIDMYVEGTLDLLELL--IMHPFLKPDDQQKEVVNMAQKAIIR 131
           KER +I    +G  D LE L  I   +  PD +Q++ +  AQK I++
Sbjct: 647 KERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVK 693


>gi|223718041 exocyst complex component 7 isoform 3 [Homo sapiens]
          Length = 656

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 87  KERTLIDMYVEGTLDLLELL--IMHPFLKPDDQQKEVVNMAQKAIIR 131
           KER +I    +G  D LE L  I   +  PD +Q++ +  AQK I++
Sbjct: 568 KERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVK 614


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.141    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,282,764
Number of Sequences: 37866
Number of extensions: 333964
Number of successful extensions: 833
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 805
Number of HSP's gapped (non-prelim): 30
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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