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Search of human proteins with 4503695
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
(207 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens] 427 e-120
gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo ... 231 4e-61
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo... 222 2e-58
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens] 219 1e-57
gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo... 218 4e-57
gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo... 217 5e-57
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 75 5e-14
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 67 1e-11
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 66 2e-11
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 66 2e-11
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 66 2e-11
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 66 2e-11
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 66 2e-11
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 63 2e-10
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 62 3e-10
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 61 8e-10
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 59 2e-09
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 59 3e-09
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 58 6e-09
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 58 6e-09
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 57 1e-08
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 57 1e-08
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 57 1e-08
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 57 1e-08
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 52 3e-07
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 52 5e-07
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 50 1e-06
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens] 48 5e-06
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens] 48 5e-06
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 48 7e-06
>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
Length = 207
Score = 427 bits (1097), Expect = e-120
Identities = 207/207 (100%), Positives = 207/207 (100%)
Query: 1 MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSR 60
MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSR
Sbjct: 1 MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSR 60
Query: 61 TSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKP 120
TSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKP
Sbjct: 61 TSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKP 120
Query: 121 DGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPK 180
DGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPK
Sbjct: 121 DGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPK 180
Query: 181 GQPELQKPFKYTTVTKRSRRIRPTHPA 207
GQPELQKPFKYTTVTKRSRRIRPTHPA
Sbjct: 181 GQPELQKPFKYTTVTKRSRRIRPTHPA 207
>gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo
sapiens]
Length = 215
Score = 231 bits (588), Expect = 4e-61
Identities = 110/192 (57%), Positives = 145/192 (75%), Gaps = 2/192 (1%)
Query: 1 MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSR 60
M S SA +CL LH L+LC Q QV V + + +F HV Q+ D +SR+ +R YQLYSR
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQVTV-QSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSR 59
Query: 61 TSGKHIQVLG-RRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGK 119
TSGKH+QVL +RI+A EDGD +A+L+VETDTFGS+VR++G ET Y+CMN+KGKL+ K
Sbjct: 60 TSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAK 119
Query: 120 PDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYP 179
+G K+CVF E VLENNYTAL +AKY GWY+ FT+KGRPRKG KTR++Q++VHFMKR P
Sbjct: 120 SNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLP 179
Query: 180 KGQPELQKPFKY 191
+G ++ ++
Sbjct: 180 RGHHTTEQSLRF 191
>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
sapiens]
Length = 204
Score = 222 bits (566), Expect = 2e-58
Identities = 107/192 (55%), Positives = 139/192 (72%), Gaps = 13/192 (6%)
Query: 1 MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSR 60
M S SA +CL LH L+LC Q Q HV Q+ D +SR+ +R YQLYSR
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQ------------HVREQSLVTDQLSRRLIRTYQLYSR 48
Query: 61 TSGKHIQVLG-RRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGK 119
TSGKH+QVL +RI+A EDGD +A+L+VETDTFGS+VR++G ET Y+CMN+KGKL+ K
Sbjct: 49 TSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAK 108
Query: 120 PDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYP 179
+G K+CVF E VLENNYTAL +AKY GWY+ FT+KGRPRKG KTR++Q++VHFMKR P
Sbjct: 109 SNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLP 168
Query: 180 KGQPELQKPFKY 191
+G ++ ++
Sbjct: 169 RGHHTTEQSLRF 180
>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
Length = 216
Score = 219 bits (559), Expect = 1e-57
Identities = 110/204 (53%), Positives = 149/204 (73%), Gaps = 12/204 (5%)
Query: 11 LCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLG 70
LCL L+LC Q Q + +F +V +Q D +SR+Q+R YQLYSRTSGKH+QV G
Sbjct: 12 LCLQLLILCCQTQG-ENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTG 70
Query: 71 RRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFI 130
RRISA EDG+K+A+L+VETDTFGS+VRIKG E+E Y+CMN++GKL+GKP G SK+CVF
Sbjct: 71 RRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFT 130
Query: 131 EKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQ------PE 184
E VLENNYTA +A++ GW++ FT++GRPR+ ++R+NQ++ HF+KR +GQ E
Sbjct: 131 EIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAE 190
Query: 185 LQKPFKY-----TTVTKRSRRIRP 203
QK F++ T TKR+RR +P
Sbjct: 191 KQKQFEFVGSAPTRRTKRTRRPQP 214
>gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo
sapiens]
Length = 233
Score = 218 bits (554), Expect = 4e-57
Identities = 111/209 (53%), Positives = 143/209 (68%), Gaps = 18/209 (8%)
Query: 1 MYSAPSACTCLCLHFLLLCFQVQ-------VLVAEENVDFRI----------HVENQTRA 43
M S SA +CL LH L+LC Q Q L E FR HV Q+
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV 60
Query: 44 RDDVSRKQLRLYQLYSRTSGKHIQVLG-RRISARGEDGDKYAQLLVETDTFGSQVRIKGK 102
D +SR+ +R YQLYSRTSGKH+QVL +RI+A EDGD +A+L+VETDTFGS+VR++G
Sbjct: 61 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 120
Query: 103 ETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKG 162
ET Y+CMN+KGKL+ K +G K+CVF E VLENNYTAL +AKY GWY+ FT+KGRPRKG
Sbjct: 121 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 180
Query: 163 PKTRENQQDVHFMKRYPKGQPELQKPFKY 191
KTR++Q++VHFMKR P+G ++ ++
Sbjct: 181 SKTRQHQREVHFMKRLPRGHHTTEQSLRF 209
>gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo
sapiens]
Length = 244
Score = 217 bits (553), Expect = 5e-57
Identities = 108/220 (49%), Positives = 144/220 (65%), Gaps = 29/220 (13%)
Query: 1 MYSAPSACTCLCLHFLLLCFQVQV----------------------------LVAEENVD 32
M S SA +CL LH L+LC Q Q + + + +
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQVTVQSSPN 60
Query: 33 FRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLG-RRISARGEDGDKYAQLLVETD 91
F HV Q+ D +SR+ +R YQLYSRTSGKH+QVL +RI+A EDGD +A+L+VETD
Sbjct: 61 FTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETD 120
Query: 92 TFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYV 151
TFGS+VR++G ET Y+CMN+KGKL+ K +G K+CVF E VLENNYTAL +AKY GWY+
Sbjct: 121 TFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYM 180
Query: 152 GFTKKGRPRKGPKTRENQQDVHFMKRYPKGQPELQKPFKY 191
FT+KGRPRKG KTR++Q++VHFMKR P+G ++ ++
Sbjct: 181 AFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRF 220
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 74.7 bits (182), Expect = 5e-14
Identities = 48/143 (33%), Positives = 81/143 (56%), Gaps = 8/143 (5%)
Query: 38 ENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGR-RISARGEDGDKYAQLLVETDTFGSQ 96
E TR+ D + +R+ +L+ RT ++++ R ++ E + Y + + T G
Sbjct: 50 ERHTRSYDYMEGGDIRVRRLFCRTQW-YLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGI- 107
Query: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS----GWYVG 152
V IKG E+EFYL MN++GKL K + +++C F E +LEN+Y SAK++ +V
Sbjct: 108 VAIKGVESEFYLAMNKEGKLYAKKE-CNEDCNFKELILENHYNTYASAKWTHNGGEMFVA 166
Query: 153 FTKKGRPRKGPKTRENQQDVHFM 175
+KG P +G KT++ Q+ HF+
Sbjct: 167 LNQKGIPVRGKKTKKEQKTAHFL 189
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 67.0 bits (162), Expect = 1e-11
Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 7/128 (5%)
Query: 53 RLYQLYSRTS-GKHIQVL--GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLC 109
RL +LY G H+Q L GR A + D +L + V I G + F++
Sbjct: 82 RLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLEL---SPVERGVVSIFGVASRFFVA 138
Query: 110 MNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQ 169
M+ KGKL G P T EC F E +L NNY A S KY G ++ +K G+ +KG +
Sbjct: 139 MSSKGKLYGSPFFTD-ECTFKEILLPNNYNAYESYKYPGMFIALSKNGKTKKGNRVSPTM 197
Query: 170 QDVHFMKR 177
+ HF+ R
Sbjct: 198 KVTHFLPR 205
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 66.2 bits (160), Expect = 2e-11
Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHIQVL-GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
LY G +++L + + D++ QL + ++ G +V IK ET YL M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVG-EVYIKSTETGQYLAMDTDGL 87
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS--GWYVGFTKKGRPRKGPKTRENQQDVH 173
L G ++EC+F+E++ EN+Y +S K++ W+VG K G ++GP+T Q+ +
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 66.2 bits (160), Expect = 2e-11
Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHIQVL-GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
LY G +++L + + D++ QL + ++ G +V IK ET YL M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVG-EVYIKSTETGQYLAMDTDGL 87
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS--GWYVGFTKKGRPRKGPKTRENQQDVH 173
L G ++EC+F+E++ EN+Y +S K++ W+VG K G ++GP+T Q+ +
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 66.2 bits (160), Expect = 2e-11
Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHIQVL-GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
LY G +++L + + D++ QL + ++ G +V IK ET YL M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVG-EVYIKSTETGQYLAMDTDGL 87
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS--GWYVGFTKKGRPRKGPKTRENQQDVH 173
L G ++EC+F+E++ EN+Y +S K++ W+VG K G ++GP+T Q+ +
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 66.2 bits (160), Expect = 2e-11
Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHIQVL-GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
LY G +++L + + D++ QL + ++ G +V IK ET YL M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVG-EVYIKSTETGQYLAMDTDGL 87
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS--GWYVGFTKKGRPRKGPKTRENQQDVH 173
L G ++EC+F+E++ EN+Y +S K++ W+VG K G ++GP+T Q+ +
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 66.2 bits (160), Expect = 2e-11
Identities = 51/145 (35%), Positives = 73/145 (50%), Gaps = 12/145 (8%)
Query: 52 LRLYQLYSRTSGKHIQVLGR-RISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCM 110
LR QLY RT G H+++ I +D ++ L + G V I+G ++ YL M
Sbjct: 61 LRRRQLYCRT-GFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGL-VSIRGVDSGLYLGM 118
Query: 111 NRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSG------WYVGFTKKGRPRKGPK 164
N KG+L G + ++ECVF E+ EN Y S Y +YV K G PR+G +
Sbjct: 119 NEKGELYGS-EKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTR 177
Query: 165 TRENQQDVHFMKR--YPKGQPELQK 187
T+ +Q+ HF+ R P PEL K
Sbjct: 178 TKRHQKFTHFLPRPVDPDKVPELYK 202
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 63.2 bits (152), Expect = 2e-10
Identities = 51/145 (35%), Positives = 72/145 (49%), Gaps = 12/145 (8%)
Query: 52 LRLYQLYSRTSGKHIQVL-GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCM 110
LR QLY RT G H+Q+L + +D + L + G V I+G ++ YL M
Sbjct: 64 LRRRQLYCRT-GFHLQILPDGSVQGTRQDHSLFGILEFISVAVGL-VSIRGVDSGLYLGM 121
Query: 111 NRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSG------WYVGFTKKGRPRKGPK 164
N KG+L G TS EC+F E+ EN Y S Y ++V K G PR G +
Sbjct: 122 NDKGELYGSEKLTS-ECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGAR 180
Query: 165 TRENQQDVHFMKR--YPKGQPELQK 187
++ +Q+ HF+ R P+ PEL K
Sbjct: 181 SKRHQKFTHFLPRPVDPERVPELYK 205
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 62.0 bits (149), Expect = 3e-10
Identities = 46/130 (35%), Positives = 66/130 (50%), Gaps = 6/130 (4%)
Query: 49 RKQLRLYQLYSRTSGKHIQVL-GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFY 107
++Q RLY + G H+QVL RIS E+ + Y+ L + T G V + G + +
Sbjct: 83 KRQRRLY--CNVGIGFHLQVLPDGRISGTHEE-NPYSLLEISTVERGV-VSLFGVRSALF 138
Query: 108 LCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRE 167
+ MN KG+L P +EC F E +L NNY A S Y G Y+ +K GR ++G K
Sbjct: 139 VAMNSKGRLYATPS-FQEECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSP 197
Query: 168 NQQDVHFMKR 177
HF+ R
Sbjct: 198 IMTVTHFLPR 207
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 60.8 bits (146), Expect = 8e-10
Identities = 44/133 (33%), Positives = 66/133 (49%), Gaps = 10/133 (7%)
Query: 52 LRLYQLYSRTSGKHIQVLGR-RISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCM 110
LR QLY RT G H+++ + D ++ L + G + I+G ++ YL M
Sbjct: 60 LRRRQLYCRT-GFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGL-ISIRGVDSGLYLGM 117
Query: 111 NRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSG------WYVGFTKKGRPRKGPK 164
N +G+L G T +ECVF E+ EN Y S Y +YV K G PR+G +
Sbjct: 118 NERGELYGSKKLT-RECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYR 176
Query: 165 TRENQQDVHFMKR 177
T+ +Q+ HF+ R
Sbjct: 177 TKRHQKFTHFLPR 189
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 59.3 bits (142), Expect = 2e-09
Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Query: 56 QLYSRTSGKHIQVL-GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKG 114
+LY + G +++ R+ E D + +L ++ + G V IKG YL M G
Sbjct: 164 RLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGV-VSIKGVCANRYLAMKEDG 222
Query: 115 KLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHF 174
+L+ T EC F E++ NNY S KY+ WYV + G+ + G KT Q+ + F
Sbjct: 223 RLLASKCVTD-ECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILF 281
Query: 175 M 175
+
Sbjct: 282 L 282
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 58.9 bits (141), Expect = 3e-09
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 11/144 (7%)
Query: 36 HVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGS 95
HV + + DV ++L + Y K+ +V G + ++ Y+ L + + G
Sbjct: 66 HVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTK-----KENCPYSILEITSVEIGV 120
Query: 96 QVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSG----WYV 151
V +K + +YL MN+KGKL G + + +C E++ EN Y S + YV
Sbjct: 121 -VAVKAINSNYYLAMNKKGKLYGSKE-FNNDCKLKERIEENGYNTYASFNWQHNGRQMYV 178
Query: 152 GFTKKGRPRKGPKTRENQQDVHFM 175
KG PR+G KTR HF+
Sbjct: 179 ALNGKGAPRRGQKTRRKNTSAHFL 202
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 57.8 bits (138), Expect = 6e-09
Identities = 48/156 (30%), Positives = 68/156 (43%), Gaps = 10/156 (6%)
Query: 30 NVDFRIHVENQTRARDDVSRKQLR--LYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLL 87
NV R+ + + R QL+ + +LYSR G H+Q+ +D D L
Sbjct: 44 NVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSR-QGYHLQLQADGTIDGTKDEDSTYTLF 102
Query: 88 VETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS 147
V I+G +T+ YL MN +G L T EC F E V EN Y S Y
Sbjct: 103 NLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTP-ECKFKESVFENYYVTYSSMIYR 161
Query: 148 ------GWYVGFTKKGRPRKGPKTRENQQDVHFMKR 177
GWY+G K+G KG ++N+ HF+ +
Sbjct: 162 QQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 197
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 57.8 bits (138), Expect = 6e-09
Identities = 46/142 (32%), Positives = 63/142 (44%), Gaps = 10/142 (7%)
Query: 44 RDDVSRKQLR--LYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKG 101
R S QL+ + +LYSR G H+Q+ +D D L V I+G
Sbjct: 5 RKSYSEPQLKGIVTKLYSR-QGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQG 63
Query: 102 KETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWYVGFTK 155
+T+ YL MN +G L T EC F E V EN Y S Y GWY+G K
Sbjct: 64 VQTKLYLAMNSEGYLYTSELFTP-ECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 122
Query: 156 KGRPRKGPKTRENQQDVHFMKR 177
+G KG ++N+ HF+ +
Sbjct: 123 EGEIMKGNHVKKNKPAAHFLPK 144
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 56.6 bits (135), Expect = 1e-08
Identities = 42/128 (32%), Positives = 57/128 (44%), Gaps = 8/128 (6%)
Query: 56 QLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
+LYSR G H+Q+ +D D L V I+G +T+ YL MN +G
Sbjct: 53 KLYSR-QGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGY 111
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWYVGFTKKGRPRKGPKTRENQ 169
L T EC F E V EN Y S Y GWY+G K+G KG ++N+
Sbjct: 112 LYTSELFTP-ECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNK 170
Query: 170 QDVHFMKR 177
HF+ +
Sbjct: 171 PAAHFLPK 178
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 56.6 bits (135), Expect = 1e-08
Identities = 42/128 (32%), Positives = 57/128 (44%), Gaps = 8/128 (6%)
Query: 56 QLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
+LYSR G H+Q+ +D D L V I+G +T+ YL MN +G
Sbjct: 53 KLYSR-QGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGY 111
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWYVGFTKKGRPRKGPKTRENQ 169
L T EC F E V EN Y S Y GWY+G K+G KG ++N+
Sbjct: 112 LYTSELFTP-ECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNK 170
Query: 170 QDVHFMKR 177
HF+ +
Sbjct: 171 PAAHFLPK 178
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 56.6 bits (135), Expect = 1e-08
Identities = 42/128 (32%), Positives = 57/128 (44%), Gaps = 8/128 (6%)
Query: 56 QLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
+LYSR G H+Q+ +D D L V I+G +T+ YL MN +G
Sbjct: 82 KLYSR-QGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGY 140
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWYVGFTKKGRPRKGPKTRENQ 169
L T EC F E V EN Y S Y GWY+G K+G KG ++N+
Sbjct: 141 LYTSELFTP-ECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNK 199
Query: 170 QDVHFMKR 177
HF+ +
Sbjct: 200 PAAHFLPK 207
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 56.6 bits (135), Expect = 1e-08
Identities = 42/128 (32%), Positives = 57/128 (44%), Gaps = 8/128 (6%)
Query: 56 QLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGK 115
+LYSR G H+Q+ +D D L V I+G +T+ YL MN +G
Sbjct: 26 KLYSR-QGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGY 84
Query: 116 LVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWYVGFTKKGRPRKGPKTRENQ 169
L T EC F E V EN Y S Y GWY+G K+G KG ++N+
Sbjct: 85 LYTSELFTP-ECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNK 143
Query: 170 QDVHFMKR 177
HF+ +
Sbjct: 144 PAAHFLPK 151
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 52.4 bits (124), Expect = 3e-07
Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 17/97 (17%)
Query: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSG-------- 148
V I+G + YL MN++G+L + S EC F+E++ E Y S Y
Sbjct: 86 VAIRGLFSGRYLAMNKRGRLYAS-EHYSAECEFVERIHELGYNTYASRLYRTVSSTPGAR 144
Query: 149 --------WYVGFTKKGRPRKGPKTRENQQDVHFMKR 177
WYV KGRPR+G KTR Q+ F+ R
Sbjct: 145 RQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPR 181
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 51.6 bits (122), Expect = 5e-07
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Query: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSG------WY 150
V I+G + +L M++KGKL T +C F E+ EN+Y SA + WY
Sbjct: 131 VGIRGVFSNKFLAMSKKGKLHASAKFTD-DCKFRERFQENSYNTYASAIHRTEKTGREWY 189
Query: 151 VGFTKKGRPRKG--PKTRENQQDVHFMKRYPKG-QPELQKPFKYTTVTKRSRRIRPTHP 206
V K+G+ ++G P+ + HF+ R+ + QPEL K I+P P
Sbjct: 190 VALNKRGKAKRGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKKPPSPIKPKIP 248
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 50.4 bits (119), Expect = 1e-06
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 7/87 (8%)
Query: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWY 150
V I+ + Y+ MN +G L P T+ EC F E V EN Y SA Y WY
Sbjct: 114 VTIQSAKLGHYMAMNAEGLLYSSPHFTA-ECRFKECVFENYYVLYASALYRQRRSGRAWY 172
Query: 151 VGFTKKGRPRKGPKTRENQQDVHFMKR 177
+G K+G+ KG + ++ + HF+ +
Sbjct: 173 LGLDKEGQVMKGNRVKKTKAAAHFLPK 199
>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
Length = 181
Score = 48.1 bits (113), Expect = 5e-06
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)
Query: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWY 150
V I+G + Y+ MN +G L D + EC F E V EN Y S Y W+
Sbjct: 54 VAIQGVKASLYVAMNGEGYLYSS-DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWF 112
Query: 151 VGFTKKGRPRKGPKTRENQQDVHFMKR 177
+G K+G+ KG + ++ + HF+ +
Sbjct: 113 LGLNKEGQIMKGNRVKKTKPSSHFVPK 139
>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
Length = 243
Score = 48.1 bits (113), Expect = 5e-06
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)
Query: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWY 150
V I+G + Y+ MN +G L D + EC F E V EN Y S Y W+
Sbjct: 116 VAIQGVKASLYVAMNGEGYLYSS-DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWF 174
Query: 151 VGFTKKGRPRKGPKTRENQQDVHFMKR 177
+G K+G+ KG + ++ + HF+ +
Sbjct: 175 LGLNKEGQIMKGNRVKKTKPSSHFVPK 201
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 47.8 bits (112), Expect = 7e-06
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 7/87 (8%)
Query: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWY 150
V I+G +T Y+ MN +G L T EC F E V EN Y S Y W+
Sbjct: 119 VAIQGVKTGLYIAMNGEGYLYPSELFTP-ECKFKESVFENYYVIYSSMLYRQQESGRAWF 177
Query: 151 VGFTKKGRPRKGPKTRENQQDVHFMKR 177
+G K+G+ KG + ++ + HF+ +
Sbjct: 178 LGLNKEGQAMKGNRVKKTKPAAHFLPK 204
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,015,242
Number of Sequences: 37866
Number of extensions: 337143
Number of successful extensions: 806
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 725
Number of HSP's gapped (non-prelim): 45
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.