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Search of human proteins with 4503465
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503465 endothelin receptor type A [Homo sapiens]
(427 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503465 endothelin receptor type A [Homo sapiens] 883 0.0
gi|169808392 endothelin receptor type B isoform 1 precursor [Hom... 478 e-135
gi|4557547 endothelin receptor type B isoform 1 precursor [Homo ... 478 e-135
gi|4503467 endothelin receptor type B isoform 2 precursor [Homo ... 457 e-129
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 172 4e-43
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 172 4e-43
gi|161484640 neuromedin B receptor [Homo sapiens] 163 3e-40
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 150 2e-36
gi|4885323 G protein-coupled receptor 37 [Homo sapiens] 137 1e-32
gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens] 129 4e-30
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 113 4e-25
gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom... 113 4e-25
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 111 1e-24
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 111 1e-24
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 111 1e-24
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 111 1e-24
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 111 1e-24
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 111 1e-24
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 111 1e-24
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 111 1e-24
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 111 1e-24
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 110 3e-24
gi|4505513 opiate receptor-like 1 [Homo sapiens] 108 7e-24
gi|33286424 opiate receptor-like 1 [Homo sapiens] 108 7e-24
gi|149944554 somatostatin receptor 4 [Homo sapiens] 105 1e-22
gi|188497623 neuromedin U receptor 1 [Homo sapiens] 104 1e-22
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 103 3e-22
gi|4557857 somatostatin receptor 1 [Homo sapiens] 102 5e-22
gi|4885057 apelin receptor [Homo sapiens] 101 1e-21
gi|223718060 opioid receptor, mu 1 isoform MOR-1G1 [Homo sapiens] 100 2e-21
>gi|4503465 endothelin receptor type A [Homo sapiens]
Length = 427
Score = 883 bits (2282), Expect = 0.0
Identities = 427/427 (100%), Positives = 427/427 (100%)
Query: 1 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP 60
METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
Sbjct: 1 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP 60
Query: 61 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA 120
SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
Sbjct: 61 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA 120
Query: 121 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS 180
SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
Sbjct: 121 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS 180
Query: 181 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM 240
VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
Sbjct: 181 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM 240
Query: 241 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ 300
LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
Sbjct: 241 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ 300
Query: 301 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM 360
RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
Sbjct: 301 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM 360
Query: 361 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS 420
NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
Sbjct: 361 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS 420
Query: 421 SHKDSMN 427
SHKDSMN
Sbjct: 421 SHKDSMN 427
>gi|169808392 endothelin receptor type B isoform 1 precursor [Homo
sapiens]
Length = 442
Score = 478 bits (1230), Expect = e-135
Identities = 228/359 (63%), Positives = 293/359 (81%), Gaps = 10/359 (2%)
Query: 69 CPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLI 128
C +I FKYINTV+SC +F++G++GN+TLLRIIY+NKCMRNGPN LIASLALGDL+
Sbjct: 90 CQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLL 149
Query: 129 YVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVA 188
++VID+PINV+KLLA WPF G +CKL PF+QK+SVGITVL+LCALS+DRYRAVA
Sbjct: 150 HIVIDIPINVYKLLAEDWPF-----GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVA 204
Query: 189 SWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSK-- 246
SWSR++GIG+P TA+EIV IW++S +LA+PEAIGF ++ +Y+G + C+L+ K
Sbjct: 205 SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTA 264
Query: 247 FMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAK 306
FM+FY+ KDWWLF FYFC+PL TA FYTLMTCEML +++G ++IAL++HLKQRREVAK
Sbjct: 265 FMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSG-MQIALNDHLKQRREVAK 323
Query: 307 TVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINP 366
TVFCLV++FALCW PLHLSRILK T+YN+ D NRCELLSFLL++DYIGIN+A++NSCINP
Sbjct: 324 TVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINP 383
Query: 367 IALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDS 425
IALY VSK+FKNCF+SCLCC C QS S+ + +++K +D + ++ RSS+K S
Sbjct: 384 IALYLVSKRFKNCFKSCLCCWC-QSFEEKQSLEEKQSCLKFKAND-HGYDNFRSSNKYS 440
>gi|4557547 endothelin receptor type B isoform 1 precursor [Homo
sapiens]
Length = 442
Score = 478 bits (1230), Expect = e-135
Identities = 228/359 (63%), Positives = 293/359 (81%), Gaps = 10/359 (2%)
Query: 69 CPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLI 128
C +I FKYINTV+SC +F++G++GN+TLLRIIY+NKCMRNGPN LIASLALGDL+
Sbjct: 90 CQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLL 149
Query: 129 YVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVA 188
++VID+PINV+KLLA WPF G +CKL PF+QK+SVGITVL+LCALS+DRYRAVA
Sbjct: 150 HIVIDIPINVYKLLAEDWPF-----GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVA 204
Query: 189 SWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSK-- 246
SWSR++GIG+P TA+EIV IW++S +LA+PEAIGF ++ +Y+G + C+L+ K
Sbjct: 205 SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTA 264
Query: 247 FMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAK 306
FM+FY+ KDWWLF FYFC+PL TA FYTLMTCEML +++G ++IAL++HLKQRREVAK
Sbjct: 265 FMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSG-MQIALNDHLKQRREVAK 323
Query: 307 TVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINP 366
TVFCLV++FALCW PLHLSRILK T+YN+ D NRCELLSFLL++DYIGIN+A++NSCINP
Sbjct: 324 TVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINP 383
Query: 367 IALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDS 425
IALY VSK+FKNCF+SCLCC C QS S+ + +++K +D + ++ RSS+K S
Sbjct: 384 IALYLVSKRFKNCFKSCLCCWC-QSFEEKQSLEEKQSCLKFKAND-HGYDNFRSSNKYS 440
>gi|4503467 endothelin receptor type B isoform 2 precursor [Homo
sapiens]
Length = 436
Score = 457 bits (1177), Expect = e-129
Identities = 212/316 (67%), Positives = 268/316 (84%), Gaps = 8/316 (2%)
Query: 69 CPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLI 128
C +I FKYINTV+SC +F++G++GN+TLLRIIY+NKCMRNGPN LIASLALGDL+
Sbjct: 90 CQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLL 149
Query: 129 YVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVA 188
++VID+PINV+KLLA WPF G +CKL PF+QK+SVGITVL+LCALS+DRYRAVA
Sbjct: 150 HIVIDIPINVYKLLAEDWPF-----GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVA 204
Query: 189 SWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSK-- 246
SWSR++GIG+P TA+EIV IW++S +LA+PEAIGF ++ +Y+G + C+L+ K
Sbjct: 205 SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTA 264
Query: 247 FMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAK 306
FM+FY+ KDWWLF FYFC+PL TA FYTLMTCEML +++G ++IAL++HLKQRREVAK
Sbjct: 265 FMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSG-MQIALNDHLKQRREVAK 323
Query: 307 TVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINP 366
TVFCLV++FALCW PLHLSRILK T+YN+ D NRCELLSFLL++DYIGIN+A++NSCINP
Sbjct: 324 TVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINP 383
Query: 367 IALYFVSKKFKNCFQS 382
IALY VSK+FKNCF++
Sbjct: 384 IALYLVSKRFKNCFKA 399
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 172 bits (437), Expect = 4e-43
Identities = 98/310 (31%), Positives = 158/310 (50%), Gaps = 13/310 (4%)
Query: 81 YINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFK 140
Y+ + I ++G++GN TL++I K MRN PN I+SLALGDL+ ++ P++ +
Sbjct: 41 YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 100
Query: 141 LLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPL 200
LA RW F G CKL PF+Q +SVG++V L ALS DRY+A+ +Q +
Sbjct: 101 YLADRWLF-----GRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALM 155
Query: 201 VTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLF 260
++ IWI+S +LAIPEA+ + PF E + + F
Sbjct: 156 KICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASF 215
Query: 261 GFYFCMPLVCTAIFYTLMTCEMLNRRNG---SLRIALSEHLKQRREVAKTVFCLVVIFAL 317
++ +PL +++Y + ++ I + + ++ R+ +AKTV V +FA
Sbjct: 216 LVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAF 275
Query: 318 CWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFK 377
CW P H+ + + Y+E+D + ++ + LA NSC+NP ALY +SK F+
Sbjct: 276 CWLPNHVIYLYRSYHYSEVDTSMLHFVTSICAR-----LLAFTNSCVNPFALYLLSKSFR 330
Query: 378 NCFQSCLCCC 387
F + L CC
Sbjct: 331 KQFNTQLLCC 340
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 172 bits (437), Expect = 4e-43
Identities = 98/310 (31%), Positives = 158/310 (50%), Gaps = 13/310 (4%)
Query: 81 YINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFK 140
Y+ + I ++G++GN TL++I K MRN PN I+SLALGDL+ ++ P++ +
Sbjct: 25 YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 84
Query: 141 LLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPL 200
LA RW F G CKL PF+Q +SVG++V L ALS DRY+A+ +Q +
Sbjct: 85 YLADRWLF-----GRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALM 139
Query: 201 VTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLF 260
++ IWI+S +LAIPEA+ + PF E + + F
Sbjct: 140 KICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASF 199
Query: 261 GFYFCMPLVCTAIFYTLMTCEMLNRRNG---SLRIALSEHLKQRREVAKTVFCLVVIFAL 317
++ +PL +++Y + ++ I + + ++ R+ +AKTV V +FA
Sbjct: 200 LVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAF 259
Query: 318 CWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFK 377
CW P H+ + + Y+E+D + ++ + LA NSC+NP ALY +SK F+
Sbjct: 260 CWLPNHVIYLYRSYHYSEVDTSMLHFVTSICAR-----LLAFTNSCVNPFALYLLSKSFR 314
Query: 378 NCFQSCLCCC 387
F + L CC
Sbjct: 315 KQFNTQLLCC 324
>gi|161484640 neuromedin B receptor [Homo sapiens]
Length = 390
Score = 163 bits (412), Expect = 3e-40
Identities = 104/331 (31%), Positives = 172/331 (51%), Gaps = 16/331 (4%)
Query: 90 IFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFD 149
I VG++GN L++I N MR+ PN I++LA GDL+ ++ +P++ A R+ FD
Sbjct: 53 IITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVD-----ASRYFFD 107
Query: 150 HNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSI 209
FG CKL P +Q +SVG++V L ALS DRYRA+ + +Q G L T ++ + I
Sbjct: 108 EWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGI 167
Query: 210 WILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLV 269
W++S +LA+PEA+ + T + + E + + +F YF +PL
Sbjct: 168 WVVSVLLAVPEAVFSEVARISSLDNSSFTACI-PYPQTDELHPKIHSVLIFLVYFLIPLA 226
Query: 270 CTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ----RREVAKTVFCLVVIFALCWFPLHLS 325
+I+Y + ++ + +L +EH K+ R+ +AK V V F CWFP H+
Sbjct: 227 IISIYYYHIAKTLIKSAH-NLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHIL 285
Query: 326 RILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLC 385
+ + YNE+D + ++ L + L+ NSC+NP ALY +S+ F+ F S LC
Sbjct: 286 YMYRSFNYNEIDPSLGHMIVTL-----VARVLSFGNSCVNPFALYLLSESFRRHFNSQLC 340
Query: 386 CCCYQSKSLMTSVPMNGTSIQWKNHDQNNHN 416
C + TS ++ ++++ + N N
Sbjct: 341 CGRKSYQERGTSYLLSSSAVRMTSLKSNAKN 371
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 150 bits (379), Expect = 2e-36
Identities = 95/306 (31%), Positives = 157/306 (51%), Gaps = 22/306 (7%)
Query: 90 IFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFD 149
I VG++GNA L+++ ++ K M+ PN I SLA GDL+ ++ +P++ LA W F
Sbjct: 57 IISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLF- 115
Query: 150 HNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSI 209
G CK+ F++ +SVG++V L LS DRY+AV Q L T ++ +
Sbjct: 116 ----GRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCV 171
Query: 210 WILSFILAIPEAIGFVMVPFE--YRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMP 267
WI+S I A+PEAI + F + ++C SK + Q++ F ++ +P
Sbjct: 172 WIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSK--KLLQEIHSLLCFLVFYIIP 229
Query: 268 LVCTAIFYTLMTCEMLNRRNGSLRIALSE------HLKQRREVAKTVFCLVVIFALCWFP 321
L +++Y+L+ + +L I E ++ R+ +A+TV LV +FALCW P
Sbjct: 230 LSIISVYYSLIARTLY---KSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLP 286
Query: 322 LHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQ 381
HL + ++ + + + + LA NSC+NP ALY++SK F+ F+
Sbjct: 287 NHLLYL----YHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFK 342
Query: 382 SCLCCC 387
+ L CC
Sbjct: 343 AQLFCC 348
>gi|4885323 G protein-coupled receptor 37 [Homo sapiens]
Length = 613
Score = 137 bits (346), Expect = 1e-32
Identities = 87/332 (26%), Positives = 156/332 (46%), Gaps = 28/332 (8%)
Query: 81 YINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFK 140
Y +S IF G++GN ++ I+ N MR+ N+L+A+LA D + + LP+ +F
Sbjct: 262 YAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFH 321
Query: 141 LLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSR-VQGIGIP 199
L +W + F CK+ P+++ +S+G+T LCAL +DR+RA + + I
Sbjct: 322 ELTKKWLLED-----FSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENC 376
Query: 200 LVTAIEIVSIWILSFILAIPEAIGFVM----VPFEYRGEQHKTCMLNATSKFME------ 249
T ++ IW+ + +LA+PE + + + F R + C++ + +
Sbjct: 377 SSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAER-CIIKISPDLPDTIYVLA 435
Query: 250 -FYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTV 308
Y + WW FG YFC+P + T I +L+T + + + ++ ++ TV
Sbjct: 436 LTYDSARLWWYFGCYFCLPTLFT-ITCSLVTARKIRKAEKACTRGNKRQIQLESQMNCTV 494
Query: 309 FCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIA 368
L +++ C P ++ I+ + + + +LL+ I L SC+ P+
Sbjct: 495 VALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNI------ISQFLLFFKSCVTPVL 548
Query: 369 LYFVSKKFKNCFQSCLCCC---CYQSKSLMTS 397
L+ + K F F C CCC C Q S +TS
Sbjct: 549 LFCLCKPFSRAFMECCCCCCEECIQKSSTVTS 580
>gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens]
Length = 481
Score = 129 bits (325), Expect = 4e-30
Identities = 82/318 (25%), Positives = 152/318 (47%), Gaps = 23/318 (7%)
Query: 81 YINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFK 140
Y +++ +F VG+VGN +++ I++ + +++ N+++ASLAL D + + LPI +F
Sbjct: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190
Query: 141 LLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYR-AVASWSRVQGIGIP 199
+ G C+ PF++ SS+G+T +LCAL +DR+ A ++ +V+ I
Sbjct: 191 EIT-----KQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERC 245
Query: 200 LVTAIEIVSIWILSFILAIPEAIGFVMV--PFEYRGEQHKTCMLNATSKFME-------F 250
++ IW+ S LA+PE + + + P G +C++ ++ E
Sbjct: 246 QSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTL-DSCIMKPSASLPESLYSLVMT 304
Query: 251 YQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFC 310
YQ+ + WW FG YFC+P++ T + L+T + S+H + ++ TV
Sbjct: 305 YQNARMWWYFGCYFCLPILFT-VTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVG 363
Query: 311 LVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALY 370
L V++A C P ++ I+ + E+ + +LL + I P+ L
Sbjct: 364 LTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFS------TFFKGAITPVLLL 417
Query: 371 FVSKKFKNCFQSCLCCCC 388
+ + F C CCCC
Sbjct: 418 CICRPLGQAFLDCCCCCC 435
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 113 bits (282), Expect = 4e-25
Identities = 92/367 (25%), Positives = 158/367 (43%), Gaps = 29/367 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHKDSMN 427
+H+ +N
Sbjct: 386 NHQVELN 392
>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
sapiens]
Length = 366
Score = 113 bits (282), Expect = 4e-25
Identities = 76/296 (25%), Positives = 141/296 (47%), Gaps = 13/296 (4%)
Query: 84 TVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLA 143
T +F+VG+ GN + ++ + + +R N ++S+A DL+ + + +P+++ +L
Sbjct: 47 TATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLL-IFLCMPLDLVRL-- 103
Query: 144 GRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTA 203
W + +FG LCKLF F+ +S TVL + ALSV+RY A+ R + +
Sbjct: 104 --WQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVK 161
Query: 204 IEIVSIWILSFILAIPEAIGFVMVPFEYRG--EQHKTCMLNATSKFMEFYQDVKDWWLFG 261
+ I IW ++F A P FV+V E+ + T T + W+
Sbjct: 162 LVIFVIWAVAFCSAGPI---FVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSS 218
Query: 262 FYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFP 321
+F +P+ C + Y+L+ ++ RR G + S + ++ K + +V F LCW P
Sbjct: 219 IFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLP 278
Query: 322 LHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFK 377
H+ R L + ++ + L+ ++ L +++ INPI +SKK++
Sbjct: 279 FHVGRYLFSKSFEPGSLEIAQISQYCNLVSFV---LFYLSAAINPILYNIMSKKYR 331
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 146 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 205
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 206 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 259
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 260 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 315
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 316 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 371
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 372 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 424
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 425 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 478
Query: 421 SHK 423
+H+
Sbjct: 479 NHQ 481
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
Length = 418
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
Length = 446
Score = 111 bits (277), Expect = 1e-24
Identities = 91/363 (25%), Positives = 156/363 (42%), Gaps = 29/363 (7%)
Query: 63 GSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASL 122
G + CP + + + +VG+ GN ++ +I + M+ N I +L
Sbjct: 53 GGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNL 112
Query: 123 ALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVD 182
AL D + LP L G WPF G LCK+ + ++ ++ LC +SVD
Sbjct: 113 ALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMFTSIFTLCTMSVD 166
Query: 183 RYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN 242
RY AV + P I V WILS + +P M +YR + C L
Sbjct: 167 RYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTKYR-QGSIDCTLT 222
Query: 243 ATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRR 302
+ +++++ +F F F MP++ + Y LM +L ++ + E + R
Sbjct: 223 FSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRMLSGSKEKDRNLR 278
Query: 303 EVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNS 362
+ + V +V +F +CW P+H+ I+K V +F + + I L NS
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVSWHFCIALGYTNS 331
Query: 363 CINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WKNHDQNNHNTDRS 420
C+NP+ F+ + FK CF+ C + S + N T I+ ++H + DR+
Sbjct: 332 CLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTRDHPSTANTVDRT 385
Query: 421 SHK 423
+H+
Sbjct: 386 NHQ 388
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 110 bits (274), Expect = 3e-24
Identities = 89/330 (26%), Positives = 147/330 (44%), Gaps = 34/330 (10%)
Query: 61 SNGSMHNYCPQ--QTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNAL 118
SNGS + Q I+ A I T + +F+VG+VGN+ ++ +I + M+ N
Sbjct: 38 SNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIY 97
Query: 119 IASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCA 178
I +LAL D + V +P L WP FG LCK+ + ++ ++ L
Sbjct: 98 IFNLALADAL-VTTTMPFQSTVYLMNSWP-----FGDVLCKIVISIDYYNMFTSIFTLTM 151
Query: 179 LSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKT 238
+SVDRY AV + PL I + IW+LS + I V+ + R +
Sbjct: 152 MSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGIS---AIVLGGTKVRED---- 204
Query: 239 CMLNATSKFMEFYQDVKDWW-------LFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLR 291
++ ++F D WW +F F F +P++ + YTLM +L ++ L
Sbjct: 205 --VDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLM---ILRLKSVRLL 259
Query: 292 IALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMD 351
E + R + + V +V +F +CW P+H+ +++ + L S+
Sbjct: 260 SGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVE--ALGSTSHSTAALSSY----- 312
Query: 352 YIGINLATMNSCINPIALYFVSKKFKNCFQ 381
Y I L NS +NPI F+ + FK CF+
Sbjct: 313 YFCIALGYTNSSLNPILYAFLDENFKRCFR 342
>gi|4505513 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 108 bits (271), Expect = 7e-24
Identities = 92/358 (25%), Positives = 159/358 (44%), Gaps = 38/358 (10%)
Query: 45 LSFLVTTHQ--PTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLL 102
LS L H P +L+L N S + P K+T Y+ + + G++GN ++
Sbjct: 22 LSLLSPNHSLLPPHLLL--NASHGAFLPLGLKVTIVGLYL------AVCVGGLLGNCLVM 73
Query: 103 RIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFP 162
+I ++ M+ N I +LAL D + V++ LP +L G WPF G LCK
Sbjct: 74 YVILRHTKMKTATNIYIFNLALADTL-VLLTLPFQGTDILLGFWPF-----GNALCKTVI 127
Query: 163 FLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAI 222
+ ++ + L A+SVDRY A+ R + V+IW L+ ++ +P AI
Sbjct: 128 AIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAI 187
Query: 223 -GFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCE 281
G V ++ C++ + +++ V +F F F +P++ ++ Y+LM
Sbjct: 188 MGSAQVE-----DEEIECLVEIPTP-QDYWGPVFAICIFLFSFIVPVLVISVCYSLMI-- 239
Query: 282 MLNRRNGSLRIALSEHLKQR--REVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKN 339
RR +R+ K R R + + V +V +F CW P+ + + + +
Sbjct: 240 ---RRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSET 296
Query: 340 RCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTS 397
+L F + Y+ NSC+NPI F+ + FK CF+ CC + + S
Sbjct: 297 AVAILRFCTALGYV-------NSCLNPILYAFLDENFKACFRK-FCCASALRRDVQVS 346
>gi|33286424 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 108 bits (271), Expect = 7e-24
Identities = 92/358 (25%), Positives = 159/358 (44%), Gaps = 38/358 (10%)
Query: 45 LSFLVTTHQ--PTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLL 102
LS L H P +L+L N S + P K+T Y+ + + G++GN ++
Sbjct: 22 LSLLSPNHSLLPPHLLL--NASHGAFLPLGLKVTIVGLYL------AVCVGGLLGNCLVM 73
Query: 103 RIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFP 162
+I ++ M+ N I +LAL D + V++ LP +L G WPF G LCK
Sbjct: 74 YVILRHTKMKTATNIYIFNLALADTL-VLLTLPFQGTDILLGFWPF-----GNALCKTVI 127
Query: 163 FLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAI 222
+ ++ + L A+SVDRY A+ R + V+IW L+ ++ +P AI
Sbjct: 128 AIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAI 187
Query: 223 -GFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCE 281
G V ++ C++ + +++ V +F F F +P++ ++ Y+LM
Sbjct: 188 MGSAQVE-----DEEIECLVEIPTP-QDYWGPVFAICIFLFSFIVPVLVISVCYSLMI-- 239
Query: 282 MLNRRNGSLRIALSEHLKQR--REVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKN 339
RR +R+ K R R + + V +V +F CW P+ + + + +
Sbjct: 240 ---RRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSET 296
Query: 340 RCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTS 397
+L F + Y+ NSC+NPI F+ + FK CF+ CC + + S
Sbjct: 297 AVAILRFCTALGYV-------NSCLNPILYAFLDENFKACFRK-FCCASALRRDVQVS 346
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 105 bits (261), Expect = 1e-22
Identities = 85/322 (26%), Positives = 144/322 (44%), Gaps = 35/322 (10%)
Query: 86 ISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGR 145
I + +VG+VGNA ++ +I + M+ N + +LA+ D +++ + +P
Sbjct: 53 IYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFM-LSVPFVASSAALRH 111
Query: 146 WPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIE 205
WPF G LC+ + ++ +V L LSVDRY AV R P V +
Sbjct: 112 WPF-----GSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLI 166
Query: 206 IVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLN----ATSKFMEFYQDVKDWWLFG 261
+ +W+ S ++ +P AI P RG Q C L A S Y +L G
Sbjct: 167 NLGVWLASLLVTLPIAIFADTRP--ARGGQAVACNLQWPHPAWSAVFVVYT-----FLLG 219
Query: 262 FYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFP 321
F +P++ + Y L+ +M R +LR + + +++ + V +VV+F LCW P
Sbjct: 220 --FLLPVLAIGLCYLLIVGKM---RAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMP 274
Query: 322 LHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQ 381
++ ++L V S ++++ + L+ NSC NPI F+S F+ FQ
Sbjct: 275 FYVVQLLNLFV-----------TSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQ 323
Query: 382 SCLC--CCCYQSKSLMTSVPMN 401
LC CC + P++
Sbjct: 324 RVLCLRCCLLEGAGGAEEEPLD 345
>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
Length = 426
Score = 104 bits (260), Expect = 1e-22
Identities = 84/322 (26%), Positives = 139/322 (43%), Gaps = 33/322 (10%)
Query: 90 IFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFD 149
IF+VG VGN +I ++K MR N + SLA+ DL+ +++ LP+ ++++ +PF
Sbjct: 70 IFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMW-HNYPF- 127
Query: 150 HNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSI 209
GV C L + +VLN+ ALSV+RY AV + + + + ++
Sbjct: 128 --LLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAV 185
Query: 210 WILSFILAIP----EAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFC 265
W L+ + ++P I + VP CML +FC
Sbjct: 186 WGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTAL----LFFC 241
Query: 266 MPLVCTAIFYTLMTCEMLNRR---------------NGSLRIALSEHLKQRREVAKTVFC 310
+P+ ++ Y L+ + R L +H + RR+V K +F
Sbjct: 242 LPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFV 301
Query: 311 LVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALY 370
LVV+F +CW P H R++ V D L+F + GI + S NP+
Sbjct: 302 LVVVFGICWAPFHADRVMWSVVSQWTDGLH---LAFQHVHVISGI-FFYLGSAANPVLYS 357
Query: 371 FVSKKFKNCFQSCLC--CCCYQ 390
+S +F+ FQ LC CC++
Sbjct: 358 LMSSRFRETFQEALCLGACCHR 379
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 103 bits (257), Expect = 3e-22
Identities = 68/307 (22%), Positives = 147/307 (47%), Gaps = 20/307 (6%)
Query: 90 IFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFD 149
IF + + GNA + ++ ++K MR N I SLAL DL+ +P+ + + ++ W
Sbjct: 55 IFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWL-- 112
Query: 150 HNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSI 209
G F+CK+ PF+Q ++V +L + ++V+R++ + +++ + +
Sbjct: 113 ---GGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVV 169
Query: 210 WILSFILAIPE-AIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPL 268
W+++ I+ P + + + +++ E+ C L + +Q + ++ F +PL
Sbjct: 170 WLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTS--PVHQKIYTTFILVILFLLPL 227
Query: 269 VCTAIFYTLMTCEM-LNRRNGSLRIALSEHLKQRREVAK-------TVFCLVVIFALCWF 320
+ I Y+ + E+ + +R G + + H K+ ++A+ + +V +FA+CW
Sbjct: 228 MVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWA 287
Query: 321 PLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCF 380
P H+ ++ + E + + + ++ IG + NS NPI F+++ FK
Sbjct: 288 PFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFS----NSICNPIVYAFMNENFKKNV 343
Query: 381 QSCLCCC 387
S +C C
Sbjct: 344 LSAVCYC 350
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 102 bits (255), Expect = 5e-22
Identities = 78/307 (25%), Positives = 134/307 (43%), Gaps = 38/307 (12%)
Query: 86 ISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGR 145
I + +VG+ GN+ ++ +I + M+ N I +LA+ D + +++ +P V L
Sbjct: 64 IYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADEL-LMLSVPFLVTSTLLRH 122
Query: 146 WPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIE 205
WPF G LC+L + ++ ++ L LSVDRY AV + P V +
Sbjct: 123 WPF-----GALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVV 177
Query: 206 IVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFY-- 263
+ +W+LS ++ +P ++V T N + WL GF
Sbjct: 178 NLGVWVLSLLVILP-----IVVFSRTAANSDGTVACNM------LMPEPAQRWLVGFVLY 226
Query: 264 -----FCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALC 318
F +P+ + Y L+ +M R +L+ + + R++ V +V++F +C
Sbjct: 227 TFLMGFLLPVGAICLCYVLIIAKM---RMVALKAGWQQRKRSERKITLMVMMVVMVFVIC 283
Query: 319 WFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKN 378
W P ++ +++ V+ E D LS + L NSC NPI F+S FK
Sbjct: 284 WMPFYVVQLV--NVFAEQDDATVSQLSVI---------LGYANSCANPILYGFLSDNFKR 332
Query: 379 CFQSCLC 385
FQ LC
Sbjct: 333 SFQRILC 339
>gi|4885057 apelin receptor [Homo sapiens]
Length = 380
Score = 101 bits (251), Expect = 1e-21
Identities = 90/319 (28%), Positives = 144/319 (45%), Gaps = 22/319 (6%)
Query: 90 IFIVGMVGNATLLRIIYQN-KCMRNGPNALIASLALGDLIYVVIDLPI-NVFKLLAGRWP 147
+F++G GN +L ++++ + R + IASLA+ DL +VV LP+ + WP
Sbjct: 38 VFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVT-LPLWATYTYRDYDWP 96
Query: 148 FDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIV 207
F G F CKL +L ++ +V L LS DRY A+ + + + A+
Sbjct: 97 F-----GTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATA 151
Query: 208 SIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDW-WLFGFYFCM 266
+W+L+ +LA+P VMV G+ T + + +W W G
Sbjct: 152 VLWVLAALLAMP-----VMV-LRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSS 205
Query: 267 PLVCTAIFYTLM-TCEMLNRRN--GSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLH 323
V + +T+M TC + G R E L++RR + + LVV FALCW P H
Sbjct: 206 TTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYH 265
Query: 324 LSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSC 383
L + L + + C+ FL+ + ++ +NSC+NP F +F+ S
Sbjct: 266 LVKTL--YMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSM 323
Query: 384 LCCCCYQSKSLMTSVPMNG 402
L CC QS+ TS +G
Sbjct: 324 L--CCGQSRCAGTSHSSSG 340
>gi|223718060 opioid receptor, mu 1 isoform MOR-1G1 [Homo sapiens]
Length = 300
Score = 100 bits (250), Expect = 2e-21
Identities = 83/315 (26%), Positives = 138/315 (43%), Gaps = 29/315 (9%)
Query: 111 MRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVG 170
M+ N I +LAL D + LP L G WPF G LCK+ + ++
Sbjct: 1 MKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF-----GTILCKIVISIDYYNMF 54
Query: 171 ITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFE 230
++ LC +SVDRY AV + P I V WILS + +P M +
Sbjct: 55 TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPV---MFMATTK 111
Query: 231 YRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSL 290
YR + C L + +++++ +F F F MP++ + Y LM +L ++ +
Sbjct: 112 YR-QGSIDCTLTFSHPTW-YWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRM 166
Query: 291 RIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLM 350
E + R + + V +V +F +CW P+H+ I+K V +F +
Sbjct: 167 LSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALV-------TIPETTFQTVS 219
Query: 351 DYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQ--WK 408
+ I L NSC+NP+ F+ + FK CF+ C + S + N T I+ +
Sbjct: 220 WHFCIALGYTNSCLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQ--QNSTRIRQNTR 273
Query: 409 NHDQNNHNTDRSSHK 423
+H + DR++H+
Sbjct: 274 DHPSTANTVDRTNHQ 288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.139 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,000,447
Number of Sequences: 37866
Number of extensions: 598576
Number of successful extensions: 2791
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 272
Number of HSP's successfully gapped in prelim test: 175
Number of HSP's that attempted gapping in prelim test: 1737
Number of HSP's gapped (non-prelim): 574
length of query: 427
length of database: 18,247,518
effective HSP length: 105
effective length of query: 322
effective length of database: 14,271,588
effective search space: 4595451336
effective search space used: 4595451336
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.