Guide to the Human Genome
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Search of human proteins with 34878757

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34878757 F-box only protein 25 isoform 3 [Homo sapiens]
         (291 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34878757 F-box only protein 25 isoform 3 [Homo sapiens]            604   e-173
gi|34878765 F-box only protein 25 isoform 2 [Homo sapiens]            548   e-156
gi|34878769 F-box only protein 25 isoform 1 [Homo sapiens]            541   e-154
gi|17158037 F-box only protein 32 isoform 1 [Homo sapiens]            364   e-101
gi|22547144 F-box only protein 32 isoform 2 [Homo sapiens]            273   1e-73
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H...    30   1.9  
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H...    30   2.5  
gi|39812378 RAN binding protein 9 [Homo sapiens]                       30   3.3  
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...    29   5.6  
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...    29   5.6  
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote...    29   5.6  
gi|239735519 SET binding factor 1 [Homo sapiens]                       28   7.3  
gi|50345997 E1A binding protein p300 [Homo sapiens]                    28   9.5  
gi|4557481 ATP-binding cassette, sub-family C (CFTR/MRP), member...    28   9.5  

>gi|34878757 F-box only protein 25 isoform 3 [Homo sapiens]
          Length = 291

 Score =  604 bits (1557), Expect = e-173
 Identities = 291/291 (100%), Positives = 291/291 (100%)

Query: 1   MEKYSIMKSMNMHRKKGKRTILEMTQILKRHGYCTLGEAFNRLDFSSAIQDIRRFNYVVK 60
           MEKYSIMKSMNMHRKKGKRTILEMTQILKRHGYCTLGEAFNRLDFSSAIQDIRRFNYVVK
Sbjct: 1   MEKYSIMKSMNMHRKKGKRTILEMTQILKRHGYCTLGEAFNRLDFSSAIQDIRRFNYVVK 60

Query: 61  LLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGV 120
           LLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGV
Sbjct: 61  LLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGV 120

Query: 121 GKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSDGW 180
           GKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSDGW
Sbjct: 121 GKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSDGW 180

Query: 181 DIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHY 240
           DIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHY
Sbjct: 181 DIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHY 240

Query: 241 PAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF 291
           PAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
Sbjct: 241 PAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF 291


>gi|34878765 F-box only protein 25 isoform 2 [Homo sapiens]
          Length = 358

 Score =  548 bits (1413), Expect = e-156
 Identities = 262/263 (99%), Positives = 263/263 (100%)

Query: 29  KRHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKI 88
           +RHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKI
Sbjct: 96  ERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKI 155

Query: 89  VQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQD 148
           VQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQD
Sbjct: 156 VQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQD 215

Query: 149 LQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQY 208
           LQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQY
Sbjct: 216 LQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQY 275

Query: 209 HFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPC 268
           HFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPC
Sbjct: 276 HFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPC 335

Query: 269 TAADPDSCFTPVSPQHFIDLFKF 291
           TAADPDSCFTPVSPQHFIDLFKF
Sbjct: 336 TAADPDSCFTPVSPQHFIDLFKF 358


>gi|34878769 F-box only protein 25 isoform 1 [Homo sapiens]
          Length = 367

 Score =  541 bits (1393), Expect = e-154
 Identities = 262/272 (96%), Positives = 263/272 (96%), Gaps = 9/272 (3%)

Query: 29  KRHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKI 88
           +RHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKI
Sbjct: 96  ERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKI 155

Query: 89  VQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQD 148
           VQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQD
Sbjct: 156 VQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQD 215

Query: 149 LQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQY 208
           LQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQY
Sbjct: 216 LQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQY 275

Query: 209 HFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFW------- 261
           HFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFW       
Sbjct: 276 HFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLAL 335

Query: 262 --KDSGHPCTAADPDSCFTPVSPQHFIDLFKF 291
             KDSGHPCTAADPDSCFTPVSPQHFIDLFKF
Sbjct: 336 LFKDSGHPCTAADPDSCFTPVSPQHFIDLFKF 367


>gi|17158037 F-box only protein 32 isoform 1 [Homo sapiens]
          Length = 355

 Score =  364 bits (934), Expect = e-101
 Identities = 171/263 (65%), Positives = 214/263 (81%)

Query: 29  KRHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKI 88
           +RHGYCTLGEAFNRLDFS+AI D RRFNYVV+LL+LIAKSQLTSLSG+AQKN+ NIL+K+
Sbjct: 93  ERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKV 152

Query: 89  VQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQD 148
           V KVL+D  N RLI++LLQ L ++LC L++ VGKSVLVGNIN+W+ R+ETIL WQQQL +
Sbjct: 153 VLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNN 212

Query: 149 LQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQY 208
           +Q+T+    GLT +DLPL +  NI+ R SDG D+++LGQ  P L++LSEDR LWKKLCQY
Sbjct: 213 IQITRPAFKGLTFTDLPLCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQY 272

Query: 209 HFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPC 268
           HF+E+Q  + LILS+KG ++WK MYF L + YP KEQYGDTL  C+HC IL WK + HPC
Sbjct: 273 HFSERQIRKRLILSDKGQLDWKKMYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPC 332

Query: 269 TAADPDSCFTPVSPQHFIDLFKF 291
           TA +P+SC   +SPQ FI+LFKF
Sbjct: 333 TANNPESCSVSLSPQDFINLFKF 355


>gi|22547144 F-box only protein 32 isoform 2 [Homo sapiens]
          Length = 210

 Score =  273 bits (698), Expect = 1e-73
 Identities = 126/209 (60%), Positives = 163/209 (77%)

Query: 83  NILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAW 142
           NIL+K+V KVL+D  N RLI++LLQ L ++LC L++ VGKSVLVGNIN+W+ R+ETIL W
Sbjct: 2   NILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHW 61

Query: 143 QQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLW 202
           QQQL ++Q+T+    GLT +DLPL +  NI+ R SDG D+++LGQ  P L++LSEDR LW
Sbjct: 62  QQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLW 121

Query: 203 KKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWK 262
           KKLCQYHF+E+Q  + LILS+KG ++WK MYF L + YP KEQYGDTL  C+HC IL WK
Sbjct: 122 KKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKLVRCYPRKEQYGDTLQLCKHCHILSWK 181

Query: 263 DSGHPCTAADPDSCFTPVSPQHFIDLFKF 291
            + HPCTA +P+SC   +SPQ FI+LFKF
Sbjct: 182 GTDHPCTANNPESCSVSLSPQDFINLFKF 210


>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
           sapiens]
          Length = 598

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 6/68 (8%)

Query: 144 QQLQDLQMTKQVN--NGLTLSD--LPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDR 199
           +QL D Q+ + +N  N +   D  LP  +  NI +++ D  ++    QV+ T  +++ED 
Sbjct: 96  EQLVD-QLIRDLNEMNDVPFFDIQLPYELAINI-FQYLDRKELGRCAQVSKTWKVIAEDE 153

Query: 200 QLWKKLCQ 207
            LW +LCQ
Sbjct: 154 VLWYRLCQ 161


>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
           sapiens]
          Length = 532

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 164 LPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQ 207
           LP  +  NI +++ D  ++    QV+ T  +++ED  LW +LCQ
Sbjct: 53  LPYELAINI-FQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQ 95


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 13/64 (20%), Positives = 31/64 (48%)

Query: 24  MTQILKRHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFN 83
           ++  L  HGYC   EAF R    + ++++       ++ +L+   ++       Q+ Y +
Sbjct: 373 VSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMGEAIETTQQLYPS 432

Query: 84  ILDK 87
           +L++
Sbjct: 433 LLER 436


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 7/119 (5%)

Query: 61   LLQLIAKSQLTS-------LSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTL 113
            +LQ++++S L         + G  Q +   ++      V  DH  P   + L+Q + +  
Sbjct: 2047 ILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVR 2106

Query: 114  CILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNI 172
              + R  G    V + +  + R  T +A  + LQ L     V+    + DL LH ++ +
Sbjct: 2107 DYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMV 2165


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 7/119 (5%)

Query: 61   LLQLIAKSQLTS-------LSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTL 113
            +LQ++++S L         + G  Q +   ++      V  DH  P   + L+Q + +  
Sbjct: 1829 ILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVR 1888

Query: 114  CILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNI 172
              + R  G    V + +  + R  T +A  + LQ L     V+    + DL LH ++ +
Sbjct: 1889 DYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMV 1947


>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
            partial [Homo sapiens]
          Length = 1700

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%)

Query: 103  KDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVN-NGLTL 161
            K +  + +    +L    G+ V +  + +W  + +  + W ++ QD    K V   G T 
Sbjct: 920  KTICAEFAILRMLLQNSEGRCVYITPMRLW--QEQVYMDWYEKFQDRLNKKVVLLTGETS 977

Query: 162  SDLPLHMLNNILYRFSDGWDIIT 184
            +DL L    NI+    + WDI++
Sbjct: 978  TDLKLLGKGNIIISTPEKWDILS 1000


>gi|239735519 SET binding factor 1 [Homo sapiens]
          Length = 1893

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 5/57 (8%)

Query: 144  QQLQDLQMTKQVNNGLTLSDLPLHMLNN---ILYRFSDGWDIITLGQVTPTLYMLSE 197
            + L+D +   Q++  L +S L + +L++   +L    DGWDI T  QV   + +LS+
Sbjct: 1412 RSLEDSEWLIQIHKLLQVSVLVVELLDSGSSVLVGLEDGWDITT--QVVSLVQLLSD 1466


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 15/62 (24%), Positives = 26/62 (41%), Gaps = 4/62 (6%)

Query: 217  RHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSC 276
            +HL  S     +W  M   ++ H  +++++  T + C+H     W    H     D D C
Sbjct: 1637 KHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRW----HCTVCEDYDLC 1692

Query: 277  FT 278
             T
Sbjct: 1693 IT 1694


>gi|4557481 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
           [Homo sapiens]
          Length = 1545

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 14/119 (11%)

Query: 61  LLQLIAKSQLTSLSGVAQKNY-----FNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCI 115
           ++  + K  LT LS +A+K Y      N++    QK++D  +   ++   +  +  ++  
Sbjct: 396 IMASVYKKALT-LSNLARKEYTVGETVNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFF 454

Query: 116 LIRGVGKSVLVG-NINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNIL 173
           L R +G SVL G  + + +  +  IL+ + +      T QV N +   D  L ++N IL
Sbjct: 455 LWRELGPSVLAGVGVMVLVIPINAILSTKSK------TIQVKN-MKNKDKRLKIMNEIL 506


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,700,461
Number of Sequences: 37866
Number of extensions: 440452
Number of successful extensions: 1470
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1461
Number of HSP's gapped (non-prelim): 15
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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