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Search of human proteins with 33469958
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33469958 serine dehydratase [Homo sapiens]
(328 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33469958 serine dehydratase [Homo sapiens] 649 0.0
gi|19923959 serine dehydratase-like [Homo sapiens] 390 e-108
gi|11345492 serine racemase [Homo sapiens] 97 3e-20
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 36 0.054
gi|169204521 PREDICTED: hypothetical protein [Homo sapiens] 33 0.27
gi|169205149 PREDICTED: hypothetical protein [Homo sapiens] 33 0.27
gi|169204400 PREDICTED: hypothetical protein [Homo sapiens] 33 0.27
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 32 0.77
gi|5031805 insulin receptor substrate 1 [Homo sapiens] 31 1.7
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 30 2.3
gi|8922477 polymerase (RNA) III (DNA directed) polypeptide E [Ho... 30 2.9
gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens] 29 6.6
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 29 6.6
gi|23397648 phosphatidylinositol glycan anchor biosynthesis, cla... 29 6.6
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 28 8.6
gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens] 28 8.6
gi|38146111 DALR anticodon binding domain containing 3 isoform 2... 28 8.6
gi|58331230 DALR anticodon binding domain containing 3 isoform 1... 28 8.6
>gi|33469958 serine dehydratase [Homo sapiens]
Length = 328
Score = 649 bits (1675), Expect = 0.0
Identities = 328/328 (100%), Positives = 328/328 (100%)
Query: 1 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 60
MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF
Sbjct: 1 MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF 60
Query: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA 120
VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA
Sbjct: 61 VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA 120
Query: 121 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180
KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL
Sbjct: 121 KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL 180
Query: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 240
QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP
Sbjct: 181 QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP 240
Query: 241 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300
IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV
Sbjct: 241 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 300
Query: 301 IVCGGSNISLAQLRALKEQLGMTNRLPK 328
IVCGGSNISLAQLRALKEQLGMTNRLPK
Sbjct: 301 IVCGGSNISLAQLRALKEQLGMTNRLPK 328
>gi|19923959 serine dehydratase-like [Homo sapiens]
Length = 329
Score = 390 bits (1001), Expect = e-108
Identities = 196/317 (61%), Positives = 249/317 (78%), Gaps = 1/317 (0%)
Query: 5 EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSS 64
EP HV TP+ +S ALS++AG V+LK ++ QPSGSFKIRGIGHFC+ AK+GC H VCSS
Sbjct: 12 EPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGCRHLVCSS 71
Query: 65 AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124
GNAG+AAAYAAR+LG+PATIV+P +T ++RL+ EGA V++ G++ DEA A+ LA
Sbjct: 72 GGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELA 131
Query: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184
K + GW +PPFD PLIW+GHAS+V+ELK L PGA+ L+VGGGGLL GVV GL EVG
Sbjct: 132 KRD-GWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEVG 190
Query: 185 WGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSE 244
W VP+IAMET GAH F+AA TAGKLV+LP ITSVAK+LG KTV A+AL+ Q I SE
Sbjct: 191 WQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSE 250
Query: 245 VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 304
V+ D EAV+A+++ +DDE++LVEPACGAALAA+YS ++++LQ EG L L S+VVIVCG
Sbjct: 251 VVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVCG 310
Query: 305 GSNISLAQLRALKEQLG 321
G+NI+ +L+ALK LG
Sbjct: 311 GNNINSRELQALKTHLG 327
>gi|11345492 serine racemase [Homo sapiens]
Length = 340
Score = 96.7 bits (239), Expect = 3e-20
Identities = 87/307 (28%), Positives = 146/307 (47%), Gaps = 20/307 (6%)
Query: 11 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAG 66
TP+ S L+++ G +++ K + Q +GSFKIRG + + V S+G
Sbjct: 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSG 85
Query: 67 NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFE-LAKALAK 125
N G A YAA+ G+PA IVVP T P ++ GA++ V E DE+ E +AK + +
Sbjct: 86 NHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASI-VYCEPSDESRENVAKRVTE 144
Query: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGW 185
G + + P +P + G +I E+ + A+ + VGGGG+L G+ ++ +
Sbjct: 145 ETEG-IMVHPNQEPAVIAGQGTIALEVLNQV-PLVDALVVPVGGGGMLAGIAITVKALK- 201
Query: 186 GDVPVIAMETFGAHSFHAATTAGKLV-SLPKITSVAKALGVK-TVGAQALKLFQEHPIFS 243
V V A E A + + GKL+ +L ++A GVK ++G + ++
Sbjct: 202 PSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIAD--GVKSSIGLNTWPIIRDLVDDI 259
Query: 244 EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVC 303
+++ E A + + K+L+EP G +AAV S Q + +P + IV
Sbjct: 260 FTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTV-------SPEVKNICIVL 312
Query: 304 GGSNISL 310
G N+ L
Sbjct: 313 SGGNVDL 319
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 35.8 bits (81), Expect = 0.054
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 170 GGLLCGVV---QGLQ-EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGV 225
G +LC +V QGL +V + VIA++ +H + K +S + A G+
Sbjct: 119 GPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISF---LIIGLAWGI 175
Query: 226 KTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEK 263
+ A L +F+E+ + E+I D E VA EK+ +EK
Sbjct: 176 SALLASPLAIFREYSLI-EIIPDFEIVACTEKWPGEEK 212
>gi|169204521 PREDICTED: hypothetical protein [Homo sapiens]
Length = 430
Score = 33.5 bits (75), Expect = 0.27
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 157 WEKPGAIALSV--GGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLP 214
WE A+ +S G GG LCG G+ +GWG G +A ++L
Sbjct: 94 WEVAVAVTVSSRWGSGGALCGTAAGM--LGWG-------RERGRPGSSSAVALESQMTLR 144
Query: 215 KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGA 272
+ + + V +L + ++S V+ + AA F E+ +EP GA
Sbjct: 145 RKKRCSVVVVVAAAPRLSLSIVWRRRLYSSVLPVTASAAAAPSFSPTEESELEPFLGA 202
>gi|169205149 PREDICTED: hypothetical protein [Homo sapiens]
Length = 430
Score = 33.5 bits (75), Expect = 0.27
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 157 WEKPGAIALSV--GGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLP 214
WE A+ +S G GG LCG G+ +GWG G +A ++L
Sbjct: 94 WEVAVAVTVSSRWGSGGALCGTAAGM--LGWG-------RERGRPGSSSAVALESQMTLR 144
Query: 215 KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGA 272
+ + + V +L + ++S V+ + AA F E+ +EP GA
Sbjct: 145 RKKRCSVVVVVAAAPRLSLSIVWRRRLYSSVLPVTASAAAAPSFSPTEESELEPFLGA 202
>gi|169204400 PREDICTED: hypothetical protein [Homo sapiens]
Length = 430
Score = 33.5 bits (75), Expect = 0.27
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 157 WEKPGAIALSV--GGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLP 214
WE A+ +S G GG LCG G+ +GWG G +A ++L
Sbjct: 94 WEVAVAVTVSSRWGSGGALCGTAAGM--LGWG-------RERGRPGSSSAVALESQMTLR 144
Query: 215 KITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGA 272
+ + + V +L + ++S V+ + AA F E+ +EP GA
Sbjct: 145 RKKRCSVVVVVAAAPRLSLSIVWRRRLYSSVLPVTASAAAAPSFSPTEESELEPFLGA 202
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 32.0 bits (71), Expect = 0.77
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 28/138 (20%)
Query: 64 SAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKAL 123
S + G+ A+ + LG P +VP TP L +EG TV + + A
Sbjct: 784 SVYSKGLDASSPSAPLGSPGVFLVPKVTPNLEPWVATDEGPTVNPMDSTVTPA------- 836
Query: 124 AKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEV 183
P D IWE + + +E + T A+ S +V L +
Sbjct: 837 -----------PSDASGIWEPGSQVFEEAESTTLSPQVALDTS---------IVTPLTTL 876
Query: 184 GWGD-VPVIAMETFGAHS 200
GD V V AM T G+ S
Sbjct: 877 EQGDKVGVPAMSTLGSSS 894
>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
Length = 1242
Score = 30.8 bits (68), Expect = 1.7
Identities = 17/33 (51%), Positives = 18/33 (54%), Gaps = 4/33 (12%)
Query: 161 GAIALSVGGGGLLCGVVQGLQEVG----WGDVP 189
GA AL GGGG C GL E G +GDVP
Sbjct: 123 GAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVP 155
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 30.4 bits (67), Expect = 2.3
Identities = 15/33 (45%), Positives = 24/33 (72%), Gaps = 1/33 (3%)
Query: 95 TIERLK-NEGATVKVVGELLDEAFELAKALAKN 126
T+E++K NE +K EL+DE F+L+K L++N
Sbjct: 285 TVEQMKQNETTAMKKQQELMDENFDLSKRLSEN 317
>gi|8922477 polymerase (RNA) III (DNA directed) polypeptide E [Homo
sapiens]
Length = 708
Score = 30.0 bits (66), Expect = 2.9
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 22/95 (23%)
Query: 99 LKNEGATV-KVVGELLDEAFELAKALAKNNPGWVYIPPFD-------------DPLIWEG 144
++ E ATV K+ E + + E A+ + N GW +I P+D ++W G
Sbjct: 367 VRKEVATVTKLCAEDVKDFLE-HMAVVRINKGWEFILPYDGEFIKKHPDVVQRQHMLWTG 425
Query: 145 HASIVKE----LKETLWEKPGAIALSVGGGGLLCG 175
+ +++ +KET+ +KP A G GL+CG
Sbjct: 426 IQAKLEKVYNLVKETMPKKPDA---QSGPAGLVCG 457
>gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens]
Length = 451
Score = 28.9 bits (63), Expect = 6.6
Identities = 16/52 (30%), Positives = 26/52 (50%)
Query: 72 AAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKAL 123
A YA +G P I+ +E L++ V V ELLD A+++A+ +
Sbjct: 249 ALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGM 300
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 28.9 bits (63), Expect = 6.6
Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 204 ATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEK 263
A+T S P ITS A +V L + E PIFS ++ + + + +
Sbjct: 2059 ASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQL 2118
Query: 264 ILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRALKEQLGMT 323
VEP A LA +Y H + L+ + P + I+ QLR L++ +
Sbjct: 2119 GPVEP-LPADLAQLYQHQLNPTLLQQQNKRP----------RTRITDDQLRVLRQYFDIN 2167
Query: 324 N 324
N
Sbjct: 2168 N 2168
>gi|23397648 phosphatidylinositol glycan anchor biosynthesis, class
O isoform 1 [Homo sapiens]
Length = 1089
Score = 28.9 bits (63), Expect = 6.6
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 14/110 (12%)
Query: 209 KLVSLPKITSVAKALGVKTVGAQALKL-------------FQEHPIFSEVISDQEAVAAI 255
KL+++P++ + A + GA AL+L F P + V ++ +
Sbjct: 598 KLLTMPRLGTSATTNPPRHNGAYALRLGIGLLLCTRLAGLFHRCPEETPVCHSSPWLSPL 657
Query: 256 EKFVDDE-KILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 304
V K L AC AAL A+ + V L+ GNL++P P ++ + G
Sbjct: 658 ASMVGGRAKNLWYGACVAALVALLAAVRLWLRRYGNLKSPEPPMLFVRWG 707
>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
sapiens]
Length = 323
Score = 28.5 bits (62), Expect = 8.6
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
Query: 162 AIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAK 221
A A +GGGG G G Q G P + H +A AG SLP++TS AK
Sbjct: 267 AAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAG---SLPRLTSDAK 323
>gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]
Length = 397
Score = 28.5 bits (62), Expect = 8.6
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 72 AAYAARQLGVPATIVVPSTTPALTIERLKNEG 103
A Y AR +G+ + +P TPALTI RL G
Sbjct: 66 AIYLARHVGL--RVGIPKETPALTINRLCGSG 95
>gi|38146111 DALR anticodon binding domain containing 3 isoform 2
[Homo sapiens]
Length = 376
Score = 28.5 bits (62), Expect = 8.6
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 6/57 (10%)
Query: 132 YIPPFDDPLIWEGHASIVKELKETLWEKPG------AIALSVGGGGLLCGVVQGLQE 182
Y P D+ L+ E S++ EL+E LW P A A G GG L V +E
Sbjct: 64 YDPNLDNCLVTEDLLSVLAELQEALWHWPEDSHPGLAGASDTGTGGCLVVHVVSCEE 120
>gi|58331230 DALR anticodon binding domain containing 3 isoform 1
[Homo sapiens]
Length = 543
Score = 28.5 bits (62), Expect = 8.6
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 6/57 (10%)
Query: 132 YIPPFDDPLIWEGHASIVKELKETLWEKPG------AIALSVGGGGLLCGVVQGLQE 182
Y P D+ L+ E S++ EL+E LW P A A G GG L V +E
Sbjct: 231 YDPNLDNCLVTEDLLSVLAELQEALWHWPEDSHPGLAGASDTGTGGCLVVHVVSCEE 287
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,047,327
Number of Sequences: 37866
Number of extensions: 507243
Number of successful extensions: 1185
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1173
Number of HSP's gapped (non-prelim): 21
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.