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Search of human proteins with 122937398
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo
sapiens]
(4314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 8599 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1548 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 1357 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 1344 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 1305 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 1268 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 1251 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 1233 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1187 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1186 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 1186 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1184 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1160 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1159 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1125 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 605 e-172
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 533 e-150
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 235 8e-61
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 204 2e-51
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 57 3e-07
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 56 7e-07
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 56 7e-07
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 56 7e-07
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 56 7e-07
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 56 7e-07
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 56 7e-07
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 56 7e-07
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 56 9e-07
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 56 9e-07
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 56 9e-07
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 8599 bits (22314), Expect = 0.0
Identities = 4314/4314 (100%), Positives = 4314/4314 (100%)
Query: 1 MANGTADVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGI 60
MANGTADVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGI
Sbjct: 1 MANGTADVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGI 60
Query: 61 SFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPML 120
SFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPML
Sbjct: 61 SFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPML 120
Query: 121 LKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTNLTKLKFKEDDTRGILTPSDEFQFWI 180
LKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTNLTKLKFKEDDTRGILTPSDEFQFWI
Sbjct: 121 LKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTNLTKLKFKEDDTRGILTPSDEFQFWI 180
Query: 181 EQAHRGNKQISKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWRQTEH 240
EQAHRGNKQISKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWRQTEH
Sbjct: 181 EQAHRGNKQISKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWRQTEH 240
Query: 241 DHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNH 300
DHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNH
Sbjct: 241 DHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNH 300
Query: 301 LTGQVWQRYVPHPWKNEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTR 360
LTGQVWQRYVPHPWKNEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTR
Sbjct: 301 LTGQVWQRYVPHPWKNEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTR 360
Query: 361 VFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQA 420
VFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQA
Sbjct: 361 VFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQA 420
Query: 421 FLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLS 480
FLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLS
Sbjct: 421 FLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLS 480
Query: 481 EVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSR 540
EVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSR
Sbjct: 481 EVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSR 540
Query: 541 DIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKI 600
DIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKI
Sbjct: 541 DIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKI 600
Query: 601 QQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGK 660
QQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGK
Sbjct: 601 QQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGK 660
Query: 661 SQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKD 720
SQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKD
Sbjct: 661 SQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKD 720
Query: 721 GLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLT 780
GLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLT
Sbjct: 721 GLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLT 780
Query: 781 YKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEAGDESIFSIMIDRNASGFLTIF 840
YKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEAGDESIFSIMIDRNASGFLTIF
Sbjct: 781 YKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEAGDESIFSIMIDRNASGFLTIF 840
Query: 841 SKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLP 900
SKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLP
Sbjct: 841 SKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLP 900
Query: 901 SAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMP 960
SAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMP
Sbjct: 901 SAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMP 960
Query: 961 QSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFEL 1020
QSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFEL
Sbjct: 961 QSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFEL 1020
Query: 1021 MMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSA 1080
MMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSA
Sbjct: 1021 MMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSA 1080
Query: 1081 KLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQG 1140
KLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQG
Sbjct: 1081 KLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQG 1140
Query: 1141 FQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYV 1200
FQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYV
Sbjct: 1141 FQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYV 1200
Query: 1201 RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTI 1260
RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTI
Sbjct: 1201 RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTI 1260
Query: 1261 REALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKG 1320
REALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKG
Sbjct: 1261 REALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKG 1320
Query: 1321 FEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMT 1380
FEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMT
Sbjct: 1321 FEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMT 1380
Query: 1381 DIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEI 1440
DIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEI
Sbjct: 1381 DIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEI 1440
Query: 1441 LGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWL 1500
LGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWL
Sbjct: 1441 LGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWL 1500
Query: 1501 NDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSL 1560
NDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSL
Sbjct: 1501 NDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSL 1560
Query: 1561 HQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHT 1620
HQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHT
Sbjct: 1561 HQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHT 1620
Query: 1621 TEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMK 1680
TEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMK
Sbjct: 1621 TEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMK 1680
Query: 1681 MGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCF 1740
MGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCF
Sbjct: 1681 MGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCF 1740
Query: 1741 DEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGG 1800
DEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGG
Sbjct: 1741 DEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGG 1800
Query: 1801 RQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQ 1860
RQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQ
Sbjct: 1801 RQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQ 1860
Query: 1861 HYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDA 1920
HYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDA
Sbjct: 1861 HYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDA 1920
Query: 1921 LIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGP 1980
LIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGP
Sbjct: 1921 LIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGP 1980
Query: 1981 SGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQ 2040
SGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQ
Sbjct: 1981 SGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQ 2040
Query: 2041 VVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLS 2100
VVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLS
Sbjct: 2041 VVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLS 2100
Query: 2101 CASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQN 2160
CASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQN
Sbjct: 2101 CASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQN 2160
Query: 2161 DYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESP 2220
DYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESP
Sbjct: 2161 DYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESP 2220
Query: 2221 PDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLS 2280
PDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLS
Sbjct: 2221 PDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLS 2280
Query: 2281 SDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVIST 2340
SDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVIST
Sbjct: 2281 SDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVIST 2340
Query: 2341 NTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENI 2400
NTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENI
Sbjct: 2341 NTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENI 2400
Query: 2401 QIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIW 2460
QIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIW
Sbjct: 2401 QIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIW 2460
Query: 2461 GSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPL 2520
GSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPL
Sbjct: 2461 GSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPL 2520
Query: 2521 DYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARH 2580
DYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARH
Sbjct: 2521 DYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARH 2580
Query: 2581 NSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRI 2640
NSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRI
Sbjct: 2581 NSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRI 2640
Query: 2641 DRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQL 2700
DRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQL
Sbjct: 2641 DRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQL 2700
Query: 2701 AGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGF 2760
AGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGF
Sbjct: 2701 AGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGF 2760
Query: 2761 FGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIP 2820
FGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIP
Sbjct: 2761 FGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIP 2820
Query: 2821 EMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFLHVYS 2880
EMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFLHVYS
Sbjct: 2821 EMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFLHVYS 2880
Query: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT
Sbjct: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
Query: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL
Sbjct: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
Query: 3001 SEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIR 3060
SEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIR
Sbjct: 3001 SEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIR 3060
Query: 3061 ESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNL 3120
ESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNL
Sbjct: 3061 ESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNL 3120
Query: 3121 KKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLD 3180
KKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLD
Sbjct: 3121 KKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLD 3180
Query: 3181 REHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDL 3240
REHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDL
Sbjct: 3181 REHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDL 3240
Query: 3241 RRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKT 3300
RRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKT
Sbjct: 3241 RRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKT 3300
Query: 3301 HLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVV 3360
HLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVV
Sbjct: 3301 HLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVV 3360
Query: 3361 QIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKP 3420
QIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKP
Sbjct: 3361 QIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKP 3420
Query: 3421 DLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQE 3480
DLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQE
Sbjct: 3421 DLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQE 3480
Query: 3481 SLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQN 3540
SLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQN
Sbjct: 3481 SLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQN 3540
Query: 3541 KQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFT 3600
KQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFT
Sbjct: 3541 KQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFT 3600
Query: 3601 GVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYN 3660
GVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYN
Sbjct: 3601 GVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYN 3660
Query: 3661 NSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRL 3720
NSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRL
Sbjct: 3661 NSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRL 3720
Query: 3721 YKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARN 3780
YKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARN
Sbjct: 3721 YKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARN 3780
Query: 3781 GDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESP 3840
GDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESP
Sbjct: 3781 GDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESP 3840
Query: 3841 PGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSL 3900
PGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSL
Sbjct: 3841 PGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSL 3900
Query: 3901 SDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVI 3960
SDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVI
Sbjct: 3901 SDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVI 3960
Query: 3961 DVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQ 4020
DVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQ
Sbjct: 3961 DVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQ 4020
Query: 4021 VISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPIL 4080
VISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPIL
Sbjct: 4021 VISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPIL 4080
Query: 4081 SFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEG 4140
SFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEG
Sbjct: 4081 SFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEG 4140
Query: 4141 PEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGR 4200
PEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGR
Sbjct: 4141 PEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGR 4200
Query: 4201 SVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWI 4260
SVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWI
Sbjct: 4201 SVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWI 4260
Query: 4261 PQDACGPYSPDECISLPVYTSAERDRVVTNIDVPCGGNQDQWIQCGAALFLKNQ 4314
PQDACGPYSPDECISLPVYTSAERDRVVTNIDVPCGGNQDQWIQCGAALFLKNQ
Sbjct: 4261 PQDACGPYSPDECISLPVYTSAERDRVVTNIDVPCGGNQDQWIQCGAALFLKNQ 4314
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1548 bits (4009), Expect = 0.0
Identities = 1229/4466 (27%), Positives = 2130/4466 (47%), Gaps = 483/4466 (10%)
Query: 180 IEQAHRGNKQISKERANYFKELFETI------AREFYNLDSLSLLEVVDLVETTQDVVDD 233
++ R + +S + K+ ET+ ++F D LS E+ D + +
Sbjct: 304 LKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATEL-DKIRQALVAIFT 362
Query: 234 VWRQTEHDHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQ 293
R+ + YP R L L++ I + K LGT L Y ++ + A + +
Sbjct: 363 HLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQT 422
Query: 294 WVIVCNHLTGQVWQRYVPHPWKNEKY-----FPETLDKLGKRLEEVLAIRTIHEKF---- 344
W L QV R + + E KL RL+++ R HE+
Sbjct: 423 WDDEYEKL--QVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI 480
Query: 345 -----------------------------LYFLPASEEKIICLTRVFEPFTGLNPVQYNP 375
+ F A I + +E ++ + +
Sbjct: 481 VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK 540
Query: 376 YTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQAFLKYKELVKRPTISK 435
W+AA+ +Y++ I E +I +L++ + +++ ++ + F ++ L RP I
Sbjct: 541 EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNA-NEMFRIFSRFNALFVRPHIRG 599
Query: 436 ELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSG-KNLSEVVNSIVWVRQLEL 494
+ + L+ R+ D I+ F+ + P + +S ++L V SI+W +Q++
Sbjct: 600 AIREYQTQLIQRVKDDIESLHDKFKVQ---YPQSQACKMSHVRDLPPVSGSIIWAKQIDR 656
Query: 495 KVDDTIKIAEALLSDLPGFRCFHQSAKDLLD----QLKLYEQEQFDDWSRDIQSGLSDSR 550
++ +K E +L G+ + K D ++KL QE FDDW+R +Q
Sbjct: 657 QLTAYMKRVEDVLGK--GWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVS 714
Query: 551 SGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANIAQKF 610
+ S+R+ N LKV++ ++ L +EVR L LGF +P I A+ A +
Sbjct: 715 GRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQL 774
Query: 611 CKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKE 670
AI L + Y +++ + +L + L K +A + W++ K
Sbjct: 775 YPFAISLIESVRTYERTCEKVEERNTISLLVAGLK-----KEVQALIAEGIALVWESYK- 828
Query: 671 LEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDL--------LRQQQRWKDGL 722
L+ Y+Q+L AE + K+ + +++ IDL + + + + L
Sbjct: 829 LDPYVQRL---AETVFNFQEKVD-------DLLIIEEKIDLEVRSLETCMYDHKTFSEIL 878
Query: 723 QELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALN-------ENLPEI 775
++ + + + S++ W + ++ + L + Q GL A E+ E+
Sbjct: 879 NRVQKAVDDLNLHSY--SNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEV 936
Query: 776 NID-----LTYKQGR-----------------LQFRPPFEEIRAKYYREMKRF----IGI 809
++D +++K G + PP EE R K Y+EM + + +
Sbjct: 937 DMDTDAPQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSL 996
Query: 810 PNQFKGVGEAG-------DESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWI- 861
P + G +E + + R G + + + +S V K W+
Sbjct: 997 PRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQ 1056
Query: 862 --VIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVI 919
+ + E + + ++ W+ ++ + + + + I+ V++ +
Sbjct: 1057 YQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKV 1116
Query: 920 DDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQER 979
+ ++ + + +++ E + ++++ + L DA + +Q
Sbjct: 1117 NLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSL 1176
Query: 980 KPEILPLFQEAE---DKNRLL---RTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQI 1033
K +I ++ E + RLL R I N++ +W F +M I+ Q+
Sbjct: 1177 KRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQV 1236
Query: 1034 EVMKGN-------VKSRLQIYYQELEKFKARWDQLKPGDDV----IETGQHNTL-DKSAK 1081
++ V+SR + EK K L+P + + I G+ L D K
Sbjct: 1237 ANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREK 1296
Query: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141
K K+ LE+T L+ E +A +D++ +W+ + +
Sbjct: 1297 CAKAKEA----LELTDTGLLSG------SEERVQVALEELQDLKG---VWSELSKVWEQI 1343
Query: 1142 QEMANEDWIT-----FRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPI 1196
+M + W++ R L ++ RLR+ + + L+ + +VI +
Sbjct: 1344 DQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIEL 1403
Query: 1197 LKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQG 1256
+ E L HW L + L + + +L G + V + A +KD+ AQG
Sbjct: 1404 ----KSEALKDRHWKQLMKRLHV--NWVVSELTLGQIWDV--DLQKNEAIVKDVLLVAQG 1455
Query: 1257 EVTIREALREL-DLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDS 1315
E+ + E L+++ ++W + L++Y++ +LI+ W D+ N+V ++ + ++K S
Sbjct: 1456 EMALEEFLKQIREVWNTYEL-DLVNYQNK----CRLIRGWDDLFNKVKEHINSVSAMKLS 1510
Query: 1316 PYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGA-----LPKEQTRFNR 1370
PYYK FE+ WE KL + +QR+WVYLE IF A LP E RF
Sbjct: 1511 PYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQS 1570
Query: 1371 VDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFY 1430
+ +F ++M + K V + G++ SL + D L + QK+L E+LE +RS+FPRFY
Sbjct: 1571 ISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFY 1630
Query: 1431 FIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKV 1490
F+GD+DLLEI+G S N + +Q H KK+FAG++S+ +E + + + S EGE V FK V
Sbjct: 1631 FVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPV 1690
Query: 1491 PLSNN--VETWLNDLALEMKKTLEQLLKECVTT----GRSSQGAVDPSLF-------PSQ 1537
++ + + WL + EM+ TL +LL E VT G+++ ++DP+ + +Q
Sbjct: 1691 SITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKAT--SIDPNTYITWIDKYQAQ 1748
Query: 1538 ILCLAEQIKFTEDVENAIKDHS-------LHQIETQLVNKLEQYTNIDTSSEDPGNTESG 1590
++ L+ QI ++E+VE A+ LH + + + L + + P
Sbjct: 1749 LVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPP------ 1802
Query: 1591 ILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHT-----CCVQMV 1645
+ KL+ LI +++H DV + L + ++ + + W Q+RFY T +QM
Sbjct: 1803 LRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMA 1862
Query: 1646 DSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGL 1705
+++F Y +EY G KLV TPLTD+CYLT+TQA++ LGG+P+GPAGTGKTESVKALG
Sbjct: 1863 NAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQ 1922
Query: 1706 LGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDAL 1765
LGR VLVFNCDE D ++MGRIFVGL + GAWGCFDEFNRLEE +LSAVS Q+Q IQ+AL
Sbjct: 1923 LGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEAL 1982
Query: 1766 KNHRT----------VCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPV 1815
+ H CELL K+V+V+ + IFITMNP GY GR LPDNLK+LFR +
Sbjct: 1983 REHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNP---GYAGRSNLPDNLKKLFRSL 2039
Query: 1816 AMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRG 1875
AM+ PD +LIA+V+LYS+GF+ A+VL+ K+V F L E L+ Q HYD+GLRALK+VL
Sbjct: 2040 AMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVS 2099
Query: 1876 SGNLLRQ---------------LNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDA 1920
+GN+ R+ +++ +N E I++Q++ + K D +
Sbjct: 2100 AGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFS 2159
Query: 1921 LIKDVFPGIELKEVEYDELSAALKQVFEEA------NYEIIPNQIKKALELYEQLCQRMG 1974
L+ DVFPG++ E L LK+V +E E+ ++K L+LY+ G
Sbjct: 2160 LLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHG 2219
Query: 1975 VVIVGPSGAGKSTLWRMLRAALCKT-GKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGV 2033
+++VGPSG+GKS WR+L AL + G + ++PKA+ + L G +D +TREW+DG+
Sbjct: 2220 LMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGL 2279
Query: 2034 LTNSARQV---VREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNV 2090
T+ R++ VR WI+ DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV
Sbjct: 2280 FTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNV 2339
Query: 2091 NFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL---RNQP-------AEYRNN 2140
+FE DL A+ AT+SR GM++ S++ + + ++L R+ P A+ R
Sbjct: 2340 RIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRK 2399
Query: 2141 LENWIGD-------------------YFE------KALQWVLKQNDYVVETSLVGTVMNG 2175
+ G+ YF KAL+ Q +++++ + + + +
Sbjct: 2400 GKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAF-QLEHIMDLTRLRCLGSL 2458
Query: 2176 LSHLH-GCRDHDEFIIN------------------LIRGLGGNLNMKSRLEFTKEVFHWA 2216
S LH CR+ ++ N L+ + +L+ SRL+ E+ +
Sbjct: 2459 FSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYI 2518
Query: 2217 RES-----PPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRG 2271
R P + P+ Y S G + + K P+ + + V+ T D R
Sbjct: 2519 RRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQ-IEVETHKVAAPDVVVPTLDTVRH 2577
Query: 2272 LDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKL 2331
WL+ +P +L GP G GK M L A L ++ ++ S+ TT LL+
Sbjct: 2578 EALLYTWLAEH--KPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTF 2635
Query: 2332 SQTCMVISTNTGRVYRPKDCER-LVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFY-D 2389
C T G V P + LVL+ +INLP +DK+GT +++F++Q++ + GFY
Sbjct: 2636 DHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRT 2695
Query: 2390 ENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPV 2449
+ WV LE IQ V + + GR L+ RF V + +DYP L IYG + +
Sbjct: 2696 SDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAM 2755
Query: 2450 LH--KNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLF 2507
L +L+ ++ L +MV+ Y + +FT D HY ++P +T+WV G+F
Sbjct: 2756 LRLIPSLRTYA--------EPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIF 2807
Query: 2508 RYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDN 2567
+ P++ ++ I A+EA RLF+D++V +E W + +D
Sbjct: 2808 --EALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERR-------------WTDENIDT 2852
Query: 2568 MSDSFYVTWGARHNSGARAAPGQPLPPHG---KPLGKLNSTDLKDVIKKGLIHYGRDNQN 2624
++ + N A +P+ K ++ +L+D +K L + + +
Sbjct: 2853 VALKHFP------NIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELD 2906
Query: 2625 LDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRG 2684
+ ++LF+EVL+++ RIDR+ P G LLL G SG G+ T++ V+ M+G ++ K+ R
Sbjct: 2907 VPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRK 2966
Query: 2685 YELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEEL 2744
Y + F DL+ VL+ +G + +++ ++++ + FLE +N+LL++GEVPGL+ +E
Sbjct: 2967 YTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEY 3026
Query: 2745 EPLLLPLKDQASQDGFF----GPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALH 2800
L+ K+ A ++G ++ +FT ++ +NLH+V M+ ++ ++PAL
Sbjct: 3027 ATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALF 3086
Query: 2801 KKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFL-------- 2852
+C + W WS ++ ++ G+++ K E K N + PD++
Sbjct: 3087 NRCVLNWFGDWSTEALYQV----------GKEFTSKMDLE--KPNYIVPDYMPVVYDKLP 3134
Query: 2853 ----------KSFLLIHESCKAYGA------------TPSRYMTFLHVYSAISSSKKKEL 2890
S + +H++ A TP Y+ F++ Y+ + K+ EL
Sbjct: 3135 QPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSEL 3194
Query: 2891 LKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQK 2950
++Q HL G+ K+ E V+EL R +S L+ K A+ L+ + Q+A ++K
Sbjct: 3195 EEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKK 3254
Query: 2951 TELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPP 3010
+ ++ ++ ++ I +++ + ++L +V+P V EA+ AV +IK + L E+RS+ PP
Sbjct: 3255 VMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPP 3314
Query: 3011 DVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKN 3070
++ LE + L+G T W ++S + + I F A IS IRE +++ N
Sbjct: 3315 AAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSN 3374
Query: 3071 KGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKL 3130
S++ + RAS A P+ W A + Y+ +L+R+ PL E LE + K + + ++
Sbjct: 3375 P-SYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEV 3433
Query: 3131 EELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQV 3190
E+++ + ++ KE++ SEA ++A+++ + + + L+ L E +RW
Sbjct: 3434 EQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTS 3493
Query: 3191 VEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWT---KSAGLE-KFDLRR--FL 3244
+++T+ L+AAFI Y + +R+ W+ + A ++ + D+ R +L
Sbjct: 3494 ETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYL 3553
Query: 3245 CTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKD 3304
E+L W++ LP+DDL ENA++ LK ++R P +IDPS QATE++ KD
Sbjct: 3554 SNADERLRWQASSLPADDLCTENAIM------LKRFNRY-PLIIDPSGQATEFIMNEYKD 3606
Query: 3305 SRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGD 3364
++ + D F LE A+RFG L++Q+++ +PVL P+L R++ G R ++ +GD
Sbjct: 3607 RKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGD 3666
Query: 3365 KIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEE 3424
+ ID + F +FLSTR+P PPD S VT VNFT TRS L+ Q L ++ E+PD++E
Sbjct: 3667 QDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDE 3726
Query: 3425 QKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKE 3484
+++ LL+ + + +++L +LE+SLL+ L +G IL++ +I +L K +A + ++E
Sbjct: 3727 KRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEE 3786
Query: 3485 SYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRAL---QNK 3541
+ + ++ YLPL+ + S +YF + L +I+ +Y++SL FL ++ L N
Sbjct: 3787 TDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNL 3846
Query: 3542 QDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDT-FT 3600
+ + QR+ + L + + + R + D + FA+ R E +D F
Sbjct: 3847 KGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQ 3906
Query: 3601 GVVVG-DMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDA-ALWRTY 3658
+ G +++ A S +I+ + E++ AV L LP+ + A + +
Sbjct: 3907 HFLRGNEIVLSAGSTPRIQG-----LTVEQAEAVVRLS-CLPAFKDLIAKVQADEQFGIW 3960
Query: 3659 YNNSMCEQEFPSILAKKV------SLFQQILVVQALRPDRLQSAMALFACKTLG--LKEV 3710
++S EQ P + +++ ++L++QA RPDRL + +F LG +
Sbjct: 3961 LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI 4020
Query: 3711 SPLPLNLKRLY-KETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQG--QA 3767
PL+L + E P+L+ PG D S +++LA + + + +G QA
Sbjct: 4021 MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA 4080
Query: 3768 DLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPI 3827
D AI ++G W+ LKN+HL WL LEK+L++LQP FRL+LT E++P
Sbjct: 4081 DKAI---NTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVN 4137
Query: 3828 LLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNY 3887
LL++ +E PPG+K N++RT+ S +I K N RA F LAWFHA QER Y
Sbjct: 4138 LLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPN-ERARLYFLLAWFHAIIQERLRY 4196
Query: 3888 IPQGWTKFYEFSLSDLRAGYNIIDR-LFDGAK--------DVQWEFVHGLLENAIYGGRI 3938
P GW+K YEF SDLR+ + +D L D AK + W + L+ +IYGGR+
Sbjct: 4197 APLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRV 4256
Query: 3939 DNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDD 3998
DN FD R+L ++L++ F + D + K + +P ++ +E +P+
Sbjct: 4257 DNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQ 4316
Query: 3999 KPSFFGLPANIAR---------SSQRMISSQVISQLRILG------RSITAGSKFDREIW 4043
PS+ GLP N R +M+ Q++ L ++ T + R W
Sbjct: 4317 TPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAW 4376
Query: 4044 SNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAA 4103
L + W L + L H K N + P+ F E +L+Q V Q LA
Sbjct: 4377 MRTLHTTASNWLHLIPQT-LSHLKRTVENIK--DPLFRFFEREVKMGAKLLQDVRQDLAD 4433
Query: 4104 LSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPE--DPLQYLRGLVARALAIQNW 4161
+ +V G ++ ++ L + L+ P +W S + P +Q++ R +QN
Sbjct: 4434 VVQVCEGKKKQTNYLRTLINELVKGILPRSW-SHYTVPAGMTVIQWVSDFSERIKQLQNI 4492
Query: 4162 VDKAEK---QALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF---VASWKGRL 4215
A + L + + L LF P+ ++ A RQ A+A S++ L V + +G
Sbjct: 4493 SLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGAT 4552
Query: 4216 QEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCF-MGWIPQDACGPYSPDECI 4274
+A ++GL L+G + + N+LS S ++S+ LP + W+ Q +
Sbjct: 4553 LDA-CSFGVTGLKLQGATCNNNKLSL----SNAISTALPLTQLRWVKQ--TNTEKKASVV 4605
Query: 4275 SLPVYTSAERDRVVTNIDVPCGGNQD 4300
+LPVY + R ++ +D +D
Sbjct: 4606 TLPVYLNFTRADLIFTVDFEIATKED 4631
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 1357 bits (3511), Expect = 0.0
Identities = 985/3539 (27%), Positives = 1726/3539 (48%), Gaps = 239/3539 (6%)
Query: 896 VERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEV 955
V++ + + + ++C+ +K + + + L++ L E+ T++ E E
Sbjct: 1001 VQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEK 1060
Query: 956 LTIMPQSVEEIGDANLQY-----SKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISN 1010
++ PQ++EE+G +LQ L + +I P+ ++ + V LE + +
Sbjct: 1061 ISRPPQTLEELG-VSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDS 1119
Query: 1011 LKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQE----LEKFKARWDQLKPGDD 1066
L +W F+ + + M+K E K + + ++ LE F+ + G
Sbjct: 1120 LNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFK------GHF 1173
Query: 1067 VIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIES 1126
G + LD+ I + + + L + F++E+P ++ K++++
Sbjct: 1174 TSNVGYMSALDQ----ITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDA 1229
Query: 1127 CAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKV-----EEHSVMTV 1181
QIW ++++ + E ++ +T+T E RL K+ + + +
Sbjct: 1230 LQQIWEIARDWEENWNEWKTGRFLILQTET--METTAHGLFRRLTKLAKEYKDRNWEIIE 1287
Query: 1182 KLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVA-DTI 1240
+S+++++K +P++ +R L HW + + E ++ + D
Sbjct: 1288 TTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQH 1347
Query: 1241 VAKAADLKDLNSRAQGEVTIREALREL-DLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIV 1299
V K + ++++ A E+ I AL+ + W V T +D + + ++ +++
Sbjct: 1348 VEK---IGEISASATKELAIEVALQNIAKTWDV----TQLDIVPYKDKGHHRLRGTEEVF 1400
Query: 1300 NQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-- 1357
+ DN+ L ++K S + K FE V WER L+ + E ++ + +QR+W+YLE IF
Sbjct: 1401 QALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGE 1460
Query: 1358 --RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSL 1415
R LP E T F++V+ ++++IM + KDN T H G+ ++L+ + L+ QKSL
Sbjct: 1461 DIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSL 1520
Query: 1416 NEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDE----KSK 1471
+ +LE KR FPRFYF+ +DDLLEILGQS NP +Q HLKK F I + + SK
Sbjct: 1521 DMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSK 1580
Query: 1472 -HITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVD 1530
M S +GE + F + V L VE+WL D+ M+ TL LL+ C R D
Sbjct: 1581 WEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRD 1640
Query: 1531 PSL--FPSQILCLAEQIKFTEDVENAIKDHSLHQIETQL-VNKLEQYTNIDTSSEDPGNT 1587
+ + Q++ A QI++T DV + + L V K Q + ++ SE
Sbjct: 1641 KWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGN 1700
Query: 1588 ESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD-HTCCVQMVD 1646
+ I+ LK+ AL+ IH DV+++L + + + W QLRFY + D C ++ +
Sbjct: 1701 LTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTN 1760
Query: 1647 SEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLL 1706
++FQY YEY GN+ +LV TPLTD+CY+TLT A+ + GG+P GPAGTGKTE+VK LG L
Sbjct: 1761 TQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKAL 1820
Query: 1707 GRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALK 1766
G V+V NC EG+D KSMGR++ GL + GAWGCFDEFNR+ VLS V+ QI I AL
Sbjct: 1821 GIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALA 1880
Query: 1767 NHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIA 1826
T G E+ + + GIFITMNP GY GR +LP+NLK +FRP+AM PD+ LIA
Sbjct: 1881 AGLTHFHFDGFEINLVWSCGIFITMNP---GYAGRTELPENLKSMFRPIAMVVPDSTLIA 1937
Query: 1827 EVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKS 1886
E+IL+ EGF + K+L++K+ +++L+ + L+ Q HYD+GLRAL ++LR +G K
Sbjct: 1938 EIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGK------KR 1991
Query: 1887 GTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQV 1946
+ + +++ ++R ++K T D F+A+++D+FP IEL ++Y +L ++Q
Sbjct: 1992 RLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQE 2051
Query: 1947 FEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAAL---CKTG--- 2000
+ + P + K +LYE R +IVG +G+GK+ WR+L+A+L C+ G
Sbjct: 2052 IRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPN 2111
Query: 2001 -KVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDID 2059
+V+++ +NPKA+ +L G D+ T EW+DG+L++ R + + WI+ DG +D
Sbjct: 2112 FNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVD 2171
Query: 2060 PEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEE 2119
WIE++NSV+DDN++LT+ +GERI V+ +FE DL+ ASPAT+SR GM++ +
Sbjct: 2172 TLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYAD 2231
Query: 2120 TDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQW-------VLKQNDYVVETSL---- 2168
++SWL +P L+ K L + ++ +Y TSL
Sbjct: 2232 LGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLY 2291
Query: 2169 --VGTVMNGLSHLHG----CRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPD 2222
+ T NG++ G F+ ++I + +++ + R K + + RE
Sbjct: 2292 SALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGR----KRIDSYLREIEGS 2347
Query: 2223 FHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLP----VIQTPDMQRGLDYFKPW 2278
F Y ++ ++ ED + P ++ T D R +Y
Sbjct: 2348 FPNKDTVYEYFVDPKIRSWT--SFEDKLPKSWRYPPNAPFYKIMVPTVDTVR-YNYLVSS 2404
Query: 2279 LSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCM 2336
L ++ + P +LVGP G GK + + L S+Q + V+ SAQTTS ++ +
Sbjct: 2405 LVAN-QNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESR-- 2461
Query: 2337 VISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVG 2396
+ T VY P + ++ ++ D+N+P D +G+ + ++ + Y +YD + +
Sbjct: 2462 -VEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK 2520
Query: 2397 -LENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLK 2455
+ + ++A+M G GR ++ R S + ++ +P + Q+ I+G + L +
Sbjct: 2521 YIREMFLMAAMGPPGG-GRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEE 2579
Query: 2456 NHSIWGSSSKIYLLAGSMVQVYEQVRAKFT-VDDYSHYFFTPCILTQWVLGLFRYDLEGG 2514
G+ ++ + + +Y V +F HY F +++ G+ R + +
Sbjct: 2580 EVKPIGN-----VVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFH 2634
Query: 2515 SSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYV 2574
+ + + +E R+F D++V A + T F G I D + F +
Sbjct: 2635 DTKSS---ITRLWIHECFRVFSDRLVDAAD--------TEAFMGI----ISDKLGSFFDL 2679
Query: 2575 TWGARHNSGARAAP--GQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQ--NLDILLF 2630
T+ H ++ P G L + T LK V++ L Y + ++LF
Sbjct: 2680 TF--HHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLF 2737
Query: 2631 HEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQF 2690
E +E+++RI RV+ P G++LL G G GR+++ L S + F ++++ Y ++F
Sbjct: 2738 REAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEF 2797
Query: 2691 KNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLP 2750
++D+K + + AG+E + + D Q +FLE IN++LSSGEVP LY +E E +
Sbjct: 2798 RDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSH 2857
Query: 2751 LKDQASQDGF---FGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLW 2807
+ DQA + +F Y R+Q NLHIVL + F PAL + W
Sbjct: 2858 IIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINW 2917
Query: 2808 MEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYG- 2866
W ++ ++ E G + N ++ + F+ +H S Y
Sbjct: 2918 FSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQ------------IFVTMHWSVAQYSQ 2965
Query: 2867 -----------ATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELN 2915
TP++Y+ L Y + K++ELL + + L+ G+ K++E + V ++
Sbjct: 2966 KMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMS 3025
Query: 2916 RKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKID 2975
+ + + Q + + L +I ++A EQ+ + +IA E +K + +
Sbjct: 3026 LELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQ 3085
Query: 2976 DELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMK 3035
+L+E P + EA A+ ++ + + EI+S PP + +++ V+ L G + +W K
Sbjct: 3086 KDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN-EPTWAEAK 3144
Query: 3036 SFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKA 3095
L ++ + + FD NIS ++ + + + + F P R S AA L WV+A
Sbjct: 3145 RQLGEQNFIKSLINFDKDNISDKVLKKIGA--YCAQPDFQPDIIGRVSLAAKSLCMWVRA 3202
Query: 3096 NIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEA 3155
Y + + P + L++ + + +E L V +K+ LK+++ + ++
Sbjct: 3203 MELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQK 3262
Query: 3156 AKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLS 3215
+L + + + ++ A +L++ L E RW V + E+L L LAAAF++Y+
Sbjct: 3263 EELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMG 3322
Query: 3216 AAPESLRKTCLEE------WTKSAGLE-KFDLRRFLCTESEQLIWKSEGLPSDDLSIENA 3268
+ R + + W F + FLC ++ W +GLPSD S EN
Sbjct: 3323 PFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENG 3382
Query: 3269 LVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFG 3328
+++ + W+ +IDP +QA +W+K L++I+ Q S+++ LE A+ FG
Sbjct: 3383 IIVTRG---NRWA----LMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFG 3435
Query: 3329 KTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIP 3387
+++Q + + ++P L P+L + + G R +++IGDK ++YN FR +++T+ NP
Sbjct: 3436 YPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYS 3495
Query: 3388 PDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESL 3447
P+ ++ T VNF GL QLL + ++ E+P+LEEQK L+ K +L +LE+ +
Sbjct: 3496 PETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEI 3555
Query: 3448 LETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESAS 3507
L L + G++L++ L+ +L+ +K ++ + E L+ S +I+ D R+AY P A+ AS
Sbjct: 3556 LRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRAS 3615
Query: 3508 KMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYIC 3567
++F+++D+ I+ MY+FSL A++ LF ++ S E RI L + VY Y C
Sbjct: 3616 ILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTC 3675
Query: 3568 RCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQ 3627
R LF+ +L+F+ H + E + D + + G ++ D + ++ + SW+
Sbjct: 3676 RTLFERHKLLFSFHMCAKI-LETSGKLNMDEYNFFLRGGVV--LDREGQMDNPCSSWL-A 3731
Query: 3628 ERSWAVATLKIALPSLYQTL-CFEDAAL-WRTYYNNSMCEQE-FPSILAKKVSLFQQILV 3684
+ W T L + + + FE W +Y N+ E+ P + Q++L+
Sbjct: 3732 DAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLI 3791
Query: 3685 VQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQEL 3744
V++LR DR+ + F LG + + P LN+K + +++ P++ I+SPG DP+ L
Sbjct: 3792 VRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSAL 3851
Query: 3745 QELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELN 3804
+LA + +H +++GQGQA +A ++L+E G W+ L N HL +SW+P L+K +
Sbjct: 3852 LQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVE 3911
Query: 3805 TLQ---PKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISK 3861
LQ P +FRLWL++ HP+F +LQ S+K+T E P GLK N+ R Y+ + Q S+
Sbjct: 3912 QLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSR 3971
Query: 3862 KDNTHR-AHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDV 3920
+ LFSL +FH+ ER+ ++ GW Y F+ SD N++ D ++
Sbjct: 3972 CSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEET 4031
Query: 3921 QWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFF-NSSVIDVFNQRNKKSIFPYSVSLP 3979
W+ + L+ YGG + + +D R+L +Y+ +F + S+ F++ + + +P
Sbjct: 4032 PWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETY----FIP 4087
Query: 3980 QSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSIT---AGS 4036
+ S+ Y+ I +P D P FG N +SQ + + L L IT AG
Sbjct: 4088 KDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGG 4147
Query: 4037 KFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQG---------SPILSFIILEQ 4087
+ E K+ + + + QK+P D +G SP+ ++ E
Sbjct: 4148 QTREE--------------KVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEI 4193
Query: 4088 FNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPLQY 4147
L+Q++ SL L K I+G ++S+ ++++ + + + P W + + +
Sbjct: 4194 QRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAW 4253
Query: 4148 LRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSL-- 4205
R L R + W +A + LS P FL A+ Q +AR SVDSL
Sbjct: 4254 TRDLAMRVEQFELWASRARPPVIFW----LSGFTFPTGFLTAVLQSSARQNNVSVDSLSW 4309
Query: 4206 KFVASW---KGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWI-- 4260
+F+ S + K + + GL LEG +D +N + L C M I
Sbjct: 4310 EFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWD----RKNSCLVEAEPMQLVCLMPTIHF 4365
Query: 4261 ------PQDACGPYSPDECISLPVYT-SAERDRVVTNIDVPCGG-NQDQWIQCGAALFL 4311
+ A G YS C P S++R V ID+ G D WI+ G AL +
Sbjct: 4366 RPAESRKKSAKGMYS-CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLM 4423
Score = 32.7 bits (73), Expect = 8.0
Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 6 ADVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGISFSNT 65
ADV+ LF+ GL +W Q + + +F D + +L + F
Sbjct: 74 ADVKPLFLSRAALT--GLADAVWTQE---HDAILEHFAQDPTESILTIFIDPC---FGLK 125
Query: 66 IEFG---DTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPMLLK 122
+E G T+++++ F + P IT EN + ++ I +L + + VFAP +
Sbjct: 126 LELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFA 185
Query: 123 DQEW 126
+ W
Sbjct: 186 NTGW 189
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 1344 bits (3478), Expect = 0.0
Identities = 1073/3959 (27%), Positives = 1853/3959 (46%), Gaps = 332/3959 (8%)
Query: 477 KNLSEVVNSIVWVRQLELKVDDTI----KIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQ 532
KN V +I W R L ++ TI ++ E L SD + Q ++ +K YE
Sbjct: 563 KNHPPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDRG--QEVKQKYLEVGRTMKEYED 620
Query: 533 EQFDDWSRDIQSGLSDSRSGLCIEASSRIMELDSN---DGLLKVHYSDRLVILLREVRQL 589
+++ W + L + SS E S + +++S L ++ E + L
Sbjct: 621 RKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYL 680
Query: 590 SALGFVIPAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQI 649
LGF +P + VA KF + ++++ Y+ + + ++ ++ + ++
Sbjct: 681 EQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRV 740
Query: 650 IKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNI 709
++ G ++ W N + YI + A + + ++ K ++ ++ I
Sbjct: 741 FRS------GYKRLNW-NSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAI 793
Query: 710 DLLR--------------------QQQRWKDGLQELRTGLA-----------TVEAQGFQ 738
+L + +++R D +R LA V +
Sbjct: 794 NLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTGK 853
Query: 739 ASDMHAWKQHWNHQLYKALEHQYQMGLEALNE----NLPEINIDLTYKQGRLQFRPPFEE 794
A + ++ ++W ++Y+ L L++ N N+P + + + P E
Sbjct: 854 APKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETILTAPEIILHPNTNE 913
Query: 795 IRAKYYREMKRFIGIPNQF------------KGVGEAGDESIFSIMIDRNASGFLT---- 838
I + ++ + I F GE + I + D + + +
Sbjct: 914 IDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAV 973
Query: 839 -IFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGK--- 894
I + L L + K + + ++D ++EK + L+ K
Sbjct: 974 MIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAY 1033
Query: 895 EVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAME 954
EV R P C+ + + + + + L L +S + L+ + + +
Sbjct: 1034 EVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAK 1093
Query: 955 VLTIMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAK 1014
L +P ++E D + + E + + L + D RT+A L K
Sbjct: 1094 NLRKIPNTLE---DLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKEL 1150
Query: 1015 WDKFELMMESHQLMIKDQIEVMK--GNVK--------SRLQIYYQELEKFKARWDQLKPG 1064
DK E + + + D + V G++K + Y ++E+F R+ PG
Sbjct: 1151 VDKIESIWSN---LFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPG 1207
Query: 1065 DDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDI 1124
+ LDK +L+ + E E +R++L + F L + + K++
Sbjct: 1208 S------VGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEM 1261
Query: 1125 ESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYL--FEEFLMNWHDRLRKVEEHSVMTVK 1182
I+ YE + +E + WI + E FL R V SV T
Sbjct: 1262 SGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSV-TYY 1320
Query: 1183 LQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFR----LLGLPRGTSLEKLLFGDLLRVAD 1238
L++++ +K IP+L ++ E L HW +L + +LE + +L + D
Sbjct: 1321 LEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTD 1380
Query: 1239 TIVAKAADLKDLNSRAQGEVTIREALRE-LDLWGVGAVFTLIDYEDSQSRTMKLIKDWKD 1297
L ++ + A EV I +A++E LD W FT++ Y ++ +
Sbjct: 1381 V-------LNEIVTAAIKEVAIEKAVKEILDTWE-NMKFTVVKYCKGTQERGYILGSVDE 1432
Query: 1298 IVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG 1357
I+ + DN LQS+ S + F V WE+ L+ + E ++ +QRKW+YLE IF
Sbjct: 1433 IIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFI 1492
Query: 1358 ----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQK 1413
R LP+E +F+ +D+ F+ IM + KD + + L + + L++CQK
Sbjct: 1493 GGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQK 1552
Query: 1414 SLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF---DEKS 1470
SLN++L+ KR+AFPRF+FI DD+LL ILG S++P +Q H+ K++ I S+ F D
Sbjct: 1553 SLNDYLDSKRNAFPRFFFISDDELLSILG-SSDPLCVQEHMIKMYDNIASLRFNDGDSGE 1611
Query: 1471 KHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVD 1530
K ++AM S EGEV+ F+ + VE W+ + EM++T + KE + + VD
Sbjct: 1612 KLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVD 1671
Query: 1531 -PSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKL--EQYTNIDTSSEDPGNT 1587
L+ ++ A Q+ +T +VE+ H + E Q + + + ID
Sbjct: 1672 WMLLYQGMVVLAASQVWWTWEVEDVF--HKAQKGEKQAMKNYGRKMHRQIDELVTRITMP 1729
Query: 1588 ESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYM-KSDHTCCVQMVD 1646
S K +++ +H D+V + + ++ W+ QLRFY + ++
Sbjct: 1730 LSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCT 1789
Query: 1647 SEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLL 1706
F Y YEY G +LV TPLTD+ YLTLTQA+ M LGG P GPAGTGKTE+ K L L
Sbjct: 1790 GTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKAL 1849
Query: 1707 GRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALK 1766
G +V NC EG+D +++G+IF GL +CGAWGCFDEFNR++ SVLS +S QIQTI++AL
Sbjct: 1850 GLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALI 1909
Query: 1767 NHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIA 1826
+ T + G+E+ ++S GIFITMNP GY GR +LP+++K LFRPV + PD + I
Sbjct: 1910 HQLTTFQFEGQEISLDSRMGIFITMNP---GYAGRTELPESVKALFRPVVVIVPDLQQIC 1966
Query: 1827 EVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKS 1886
E++L+SEGF +AK L++K+ ++ L+RE L+ Q HYD+GLRALK+VL +G L R
Sbjct: 1967 EIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRG---- 2022
Query: 1887 GTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQV 1946
+ + E ++++ALR + KF F D F LI D+FPG++ V Y + + A++QV
Sbjct: 2023 --SSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQV 2080
Query: 1947 FEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQY 2006
EE Y ++P Q+ K ++++E + R ++VGP+ GKS + L A K G K Y
Sbjct: 2081 LEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLY 2140
Query: 2007 TMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSS--WIICDGDIDPEWIE 2064
+NPKA+ +L G +D TR+W+DGVL+N R++ +P D +I+ DGD+D W+E
Sbjct: 2141 ILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREI-NKPTDKKERKYILFDGDVDALWVE 2199
Query: 2065 SLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNS 2124
++NSV+DDNRLLT+ +GERI+ + +FE DL ASPAT+SR GM+++ +
Sbjct: 2200 NMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRP 2259
Query: 2125 LIKSWLRNQPAEYRNNLENW-IGDYFEKALQWVLKQNDYVVETSLVG------------T 2171
K W+ P N +E + + FEK + +++ D +VE + G T
Sbjct: 2260 YWKKWVNQIP----NKVEQYNLNSLFEKYVPYLM---DVIVEGIVDGRQAEKLKTIVPQT 2312
Query: 2172 VMNGLSHLHGCRD-------------HDEFIINLIRGLGGNLNMKSRLEFTKEVFH---- 2214
+N ++ L D F+ L LG +L R++F + +
Sbjct: 2313 DLNMVTQLAKMLDALLEGEIEDLDLLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASL 2372
Query: 2215 --------WAR--ESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADD--FSNGLTLPV 2262
WA E P D ++D+ R + + PE + A + F N L
Sbjct: 2373 STVDTEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAPERKFINIL---- 2428
Query: 2263 IQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQL--RSTQIATVHCSA 2320
+ T D R + + KQP I VG G K + L + + V+ S+
Sbjct: 2429 VHTVDTTRTTWILEQMVK--IKQPVIFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSS 2486
Query: 2321 QTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQ 2380
+TTS + + L + T Y P +RL++++ D+N+P++D++GT +A L+
Sbjct: 2487 RTTSMDIQRNLEAN---VEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKL 2543
Query: 2381 VLTYQGFYD--ENLEWVGLENIQIVASM-SAGGRLGRHKLTTRFTSIVRLCSIDYPEREQ 2437
+L YD + L + ++ +A+M AGG GR+++ RF S+ + ++ +P E
Sbjct: 2544 LLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGG--GRNEVDPRFISLFSVFNVPFPSEES 2601
Query: 2438 LQTIYGAYLEPVLHKNLKNHSIWGSSSKI----YLLAGSMVQVYEQVRAKFTVDDYSHYF 2493
L IY + L+ H + + SI S K+ L ++VQ +KF HY
Sbjct: 2602 LHLIYSSILKG--HTSTFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKF------HYI 2653
Query: 2494 FTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILT 2553
F L++ GL L + ++ + E R+F D+++ + L
Sbjct: 2654 FNLRDLSRVFNGLV---LTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQL------ 2704
Query: 2554 SVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTD---LKDV 2610
Q GS ++++ D V Q G+P + D K +
Sbjct: 2705 --VQQHIGSLVVEHFKDDVEVVM----RDPILFGDFQMALHEGEPRIYEDIQDYEAAKAL 2758
Query: 2611 IKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSH 2670
++ L Y N ++++LF + LE+++R+ R++ G LL G G G+++++ L +
Sbjct: 2759 FQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAF 2818
Query: 2671 MHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLL 2730
+F +SRGY F+ DLK + GIE + ++ L D FLE+IN++L
Sbjct: 2819 TASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNML 2878
Query: 2731 SSGEVPGLYTLEELEPLLLPLKDQASQDGFFGP----VFNYFTYRIQQNLHIVLIMDSAN 2786
+SG VP L++ EE E +L + +A + G GP V+ YF + NLHIVL M
Sbjct: 2879 TSGIVPALFSEEEKESILSQIGQEALKQG-MGPAKESVWQYFVNKSANNLHIVLGMSPVG 2937
Query: 2787 SNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNS 2846
C + P + + W W ++ + + YN E +
Sbjct: 2938 DTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLG-------YNPMIPAENIE--- 2987
Query: 2847 VDPDFLKSFLLIHESCKAYG------------ATPSRYMTFLHVYSAISSSKKKELLKRQ 2894
+ +K +L+H+S Y TP Y+ F++ YS + K + + +
Sbjct: 2988 ---NVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQC 3044
Query: 2895 SHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELE 2954
L G+ KL EA +DELN+K EQ ++L K +A L+ I V+ A E+K E
Sbjct: 3045 KRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
Query: 2955 RLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIR 3014
I E+ I K + + L EV P++ AKL + + ++EIRS PP ++
Sbjct: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQ 3164
Query: 3015 DILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSF 3074
+ E +L + G + +W + K ++ + D +I++ ++++ LL +
Sbjct: 3165 TVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTT 3224
Query: 3075 DPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELL 3134
+ A S A + +V+A + Y V I P + A LE N T+ +++ L
Sbjct: 3225 EEMEA--VSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNEL 3282
Query: 3135 NSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEIT 3194
++ +++ L K+++ E KL+ E + + AA+ LI+ L E+ RW + E+
Sbjct: 3283 AAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELM 3342
Query: 3195 EELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEK-------FDLRRFLCTE 3247
L L AAF++Y A R + ++ LE+ F L L +
Sbjct: 3343 HRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDD 3402
Query: 3248 SEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRL 3307
E W S+GLP D+LS++N + L + + P IDP QA W+K + + L
Sbjct: 3403 VEISRWGSQGLPPDELSVQNGI-------LTTRASRFPLCIDPQQQALNWIKRKEEKNNL 3455
Query: 3308 EVINQQDSNFITALELAVRFGKTLIIQEMDG-VEPVLYPLLRRDL-VAQGPRYVVQIGDK 3365
V + D +F+ LE+++++G + +++D ++PV+ +L +++ V+QG ++++ +GDK
Sbjct: 3456 RVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFII-LGDK 3514
Query: 3366 IIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQ 3425
+DY+ FRL+L+T+ NP P +N+T T GL QLL++ + +E+ +LEEQ
Sbjct: 3515 EVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQ 3574
Query: 3426 KTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKES 3485
+ L+Q+ + K L LE+SLL LATS GN+L+N DL+ +L +TK+ + + E LK +
Sbjct: 3575 REHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLA 3634
Query: 3486 YKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSE 3545
K + +D+ RD Y P A + ++F++S+++ +N+MY++SL AFL +F+ +L+
Sbjct: 3635 EKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDS 3694
Query: 3546 NTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPE--LFQENEWDTFTGVV 3603
+R+++++ +L +Y + C LF+ +L+F+ + + + E D F
Sbjct: 3695 ILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFF---- 3750
Query: 3604 VGDMLRKADSQQKIRDQLP-SWIDQERSWAVATLKIALPSLYQTL---CFEDAALWRTYY 3659
L+ S +K + + P +W+ + + L + L + +W+ +Y
Sbjct: 3751 ----LKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWY 3806
Query: 3660 NNSMCEQEFPSILA--KKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNL 3717
+ EQ FP L ++ FQ++L+++ R DR+ A+ + T+G K V P ++
Sbjct: 3807 DLDSLEQ-FPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISF 3865
Query: 3718 KRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQ---VAMGQGQADLAIQML 3774
+ +++++ PI+ I+SPG+DP+ +L +L AERSG ++ +AMGQGQ +A+Q+L
Sbjct: 3866 EAIFEQSTPHSPIVFILSPGSDPATDLMKL--AERSGFGGNRLKFLAMGQGQEKVALQLL 3923
Query: 3775 KECARNGDWLCLKNLHLVVSWLPVLEKELNTL-QPKDTFRLWLTAEVHPNFTPILLQSSL 3833
+ G WL L+N HL+V WL LEK L + +P FRLWLT + F +LQ SL
Sbjct: 3924 ETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSL 3983
Query: 3834 KITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWT 3893
K+ E P GLK N+ TY + E + + + ++ LA+FHA QERR + GW
Sbjct: 3984 KVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWN 4043
Query: 3894 KFYEFSLSDLRAGYNIIDRLFDGA-----KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQ 3948
+Y+F+ SD + I++ A + W + L+ +YGGR + FD R+L
Sbjct: 4044 VYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILT 4103
Query: 3949 SYLKQFFNSSVIDVFNQ----RNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFG 4004
Y+ ++ + D F RNK+ +P + IE +P + P FG
Sbjct: 4104 IYMDEYLGDFIFDTFQPFHFFRNKE----VDYKIPVGDEKEKFVEAIEALPLANTPEVFG 4159
Query: 4005 LPANIARSSQRMISSQVISQ-LRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNL 4063
L N + + + L + ++ + S R+ + +++ + K+ + +L
Sbjct: 4160 LHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIE--NKMPKVFDL 4217
Query: 4064 IHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLAS 4123
+ + ++ LE+FN +LV + +SLA L + + G +S+E+ +A
Sbjct: 4218 DQVRKRLGTGLSPTSVVLLQELERFN--KLVVRMTKSLAELQRALAGEVGMSNELDDVAR 4275
Query: 4124 ALLNQKCPLAWQSKWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFH 4182
+L P W+ L ++ + R WV ++E + LS L
Sbjct: 4276 SLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMW-----LSGLHI 4330
Query: 4183 PDTFLNALRQETARAVGRSVD-SLKFVASWKGR-----LQEAKLQIKISGLLLEGCSFD 4235
P+++L AL Q T R G +D S F K + + A +SGL LEG +D
Sbjct: 4331 PESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWD 4389
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 1305 bits (3377), Expect = 0.0
Identities = 947/3400 (27%), Positives = 1656/3400 (48%), Gaps = 311/3400 (9%)
Query: 1106 HFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMN 1165
+F++E F +S +++ +W + E+ + QE W+ ++K + ++N
Sbjct: 868 NFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQE-----WL--KSKFDCLDPEVLN 920
Query: 1166 WH--------DRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFR-- 1215
+L K + + +L+ +V+K K +P++ +R L HW + +
Sbjct: 921 GQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTV 980
Query: 1216 ---LLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGV 1272
L+ +LE+L L V D +++D++ +A GE + L++++
Sbjct: 981 DATLVDAEIPLTLERL---SQLHVFDF----GQEIQDISGQASGEAALEAILKKVEDSWK 1033
Query: 1273 GAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKL 1332
F ++ + DS+ + ++ DI + D+ + +L S Y + +V W+++L
Sbjct: 1034 TTEFVILPHRDSKD--VFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQL 1091
Query: 1333 AELDEYLQNLNHIQRKWVYLEPIFG----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRV 1388
A ++ L+ QR W+YLE IF + LP E F +VD+ ++ IM + +
Sbjct: 1092 ALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNA 1151
Query: 1389 TTLTTHAGIRNSLLT---ILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQST 1445
T G+ + +LDQ+Q+C L +LE KR FPRFYF+ +D+LLEIL Q+
Sbjct: 1152 LRAATQPGLLETFQNNNALLDQIQKC---LEAYLESKRVIFPRFYFLSNDELLEILAQTR 1208
Query: 1446 NPSVIQSHLKKLFAGINSVCF----------------DEK--SKHITAMKSLEGEVVPFK 1487
NP +Q HL+K F I+ + F EK + I AM S EGE V
Sbjct: 1209 NPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLG 1268
Query: 1488 NKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLF----PSQILCLAE 1543
+ NVE WL + M +L +L K + QG + PSQ++
Sbjct: 1269 KGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIA---DYQGKLRTDWVVAGHPSQVILTVS 1325
Query: 1544 QIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLK------ 1597
QI + D+ + ET+ N ++ N + + + N + I++ L
Sbjct: 1326 QIMWCRDLTECL--------ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNI 1377
Query: 1598 --ALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD-HTCCVQMVDSEFQYTYE 1654
ALI +H D+V +L Q +V T E + W++QLR+Y D C +M S++ Y YE
Sbjct: 1378 LTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYE 1437
Query: 1655 YQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFN 1714
Y G +LV TPLTD+CYL L A+++ LGG P GPAGTGKTE+ K L L Q +VFN
Sbjct: 1438 YLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFN 1497
Query: 1715 CDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCEL 1774
C +G+D K MGR F GL + GAW CFDEFNR++ VLS ++ Q+ TI++A +
Sbjct: 1498 CSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMF 1557
Query: 1775 LGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEG 1834
G+E+++ FITMNP GY GR +LPDNLK LFRP AM P+ LIAEVILYSEG
Sbjct: 1558 EGREIKLVMTCAAFITMNP---GYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEG 1614
Query: 1835 FKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANE 1894
F+ +K+L+RK+ ++ L E L+ Q HYD+G+RA+K+VL +G+L R+ + NE
Sbjct: 1615 FESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRE------NPDLNE 1668
Query: 1895 SHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEI 1954
++++AL+ + + KF D F +I D+FPG+++ E +Y L + + V N +
Sbjct: 1669 DVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQP 1728
Query: 1955 IPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKV---------VKQ 2005
++K ++ YE + R GV++VGP+G GK+T++R+L L K+ VK
Sbjct: 1729 EMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKT 1788
Query: 2006 YTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIES 2065
Y +NPK++ +L G ++ T EW DG++ S R V + + WII DG +D WIE+
Sbjct: 1789 YVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIEN 1848
Query: 2066 LNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSL 2125
+N+VLDDN++L + + ERI+ P ++ +FE DL ASPAT+SR GM+F+ EE
Sbjct: 1849 MNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPY 1908
Query: 2126 IKSWLRNQPAEYRNNLENWIGDYFEK----ALQWVLKQNDYV---VETSLVGTVMNGLSH 2178
+K+W++ + + +I + F++ L ++ K+ V+ S V T+ L
Sbjct: 1909 VKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLES 1968
Query: 2179 LHGCRDH---------------DEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESP--- 2220
L +D F+ + LGGNL F + ++P
Sbjct: 1969 LILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDAR 2028
Query: 2221 -PDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLP----VIQTPDMQRGLDYF 2275
P+ + D RL P + F +P ++ T D R
Sbjct: 2029 LPNSGDLWSIHMDFDTKRL------DPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLM 2082
Query: 2276 KPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQ---IATVHCSAQTTSRHLLQKLS 2332
+ L+ K + G G GK ++ + ++++ + ++ SAQT+S + +
Sbjct: 2083 EKLLA--VKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIE 2140
Query: 2333 QTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN- 2391
+ + +R+V+++ D+N+P+LD++G+ + L+Q + GFYD N
Sbjct: 2141 SK---LERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK 2197
Query: 2392 LEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLH 2451
L W ++++ I+++ + G GR+ +T RF + + P L+ I+ A L
Sbjct: 2198 LFWKEIQDVTIISACAPPGG-GRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAIL----- 2251
Query: 2452 KNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVD-----DYSHYFFTPCILTQWVLGL 2506
N + + A S+V+ ++ K +VD SHY F L++ V G+
Sbjct: 2252 ----NGFLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGI 2307
Query: 2507 FRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILD 2566
+ D G+ + + + +E +R+F D+++ ++ H F +ILT + +G I
Sbjct: 2308 LQCD--PGTIREEIQ-IFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDL 2364
Query: 2567 NMSDSFYVTWGARHNSGARAAPG--QPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDN-Q 2623
+ + +G GA A +P K +V++ L Y N +
Sbjct: 2365 EYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTA---------NVLQDYLDDYNLTNPK 2415
Query: 2624 NLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISR 2683
+ ++ F + +E++SRI R++ G+ LL G G G++++T L +H+ G ++SR
Sbjct: 2416 EVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSR 2475
Query: 2684 GYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEE 2743
GY F DL+ + ++AG+E + +V L D Q V FLE IN++L+SGEVP L+ +E
Sbjct: 2476 GYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDE 2535
Query: 2744 LEPLLLPLKDQASQ----DGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPAL 2799
LE +L + +A + +G VF YF +++Q LHIVL M F C P+L
Sbjct: 2536 LEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSL 2595
Query: 2800 HKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLL-- 2857
C + W W ++ + + FS+ G +++ KE+ V+ S +
Sbjct: 2596 VNCCTIDWFVQWPREALLSVSKTFFSQVDAG----NEELKEKLPLMCVNVHLSVSSMAER 2651
Query: 2858 -IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNR 2916
+E + Y TP+ Y+ +++Y ++ S K+K+++ + ++ G++KL E LVD++
Sbjct: 2652 YYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKL 2711
Query: 2917 KAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDD 2976
+L K ++ +A ++ + V + A + + ++ + A VK EE + DD
Sbjct: 2712 DLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDE---ATAKVKAEETQAIADD 2768
Query: 2977 ---ELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVS 3033
+L E P ++ A A+ ++ +SEIR PPD++ ++E + L+ W S
Sbjct: 2769 AQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNA-KPDWPS 2827
Query: 3034 MKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWV 3093
K L + + +D NI +I +++ + N F P+ ++ S A + WV
Sbjct: 2828 AKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYI--NNPDFVPEKVEKVSKACKSMCMWV 2885
Query: 3094 KANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTS 3153
+A YS V++ + P + ++ L T R+ + LL V ++ L++++ +
Sbjct: 2886 RAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVN 2945
Query: 3154 EAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITY 3213
E L ++ + + A L L+ E RW + + EE++ + +AAA + Y
Sbjct: 2946 EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAY 3005
Query: 3214 LSAAPESLRKTCLEEWTKSA-GLE-----KFDLRRFLCTESEQLIWKSEGLPSDDLSIEN 3267
A R++ +E W + LE F L L E W ++GLP D +S EN
Sbjct: 3006 YGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTEN 3065
Query: 3268 ALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRF 3327
+++ Q R P +IDP QA W++ S L++I DSNF+ LE ++R
Sbjct: 3066 GILVTQ-------GRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRL 3118
Query: 3328 GKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFI 3386
G ++++E+ + ++P L P+L + + G R ++++GD IDY++ FR +++T+ PNP
Sbjct: 3119 GLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHY 3178
Query: 3387 PPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEES 3446
P+ VT +NFT T+SGL QLL+ ++ EKP LEEQ+ KL+ + K QL +EE
Sbjct: 3179 LPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEK 3238
Query: 3447 LLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESA 3506
+L L TS+GNIL+N++LI++L +K +S I+ L+E+ + ++ R+ Y P+A
Sbjct: 3239 ILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQG 3298
Query: 3507 SKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYI 3566
S MYF+I+ LS+I+ MY++SL F +LF ++ +EN +QR+ L+ Y +
Sbjct: 3299 SVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNV 3358
Query: 3567 CRCLFKADQLMFALHFVRGMHPE--LFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPS- 3623
R LF+ +L+++ M + + EW+ F LR + +K R P
Sbjct: 3359 SRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFF--------LRGSAGLEKERPPKPEA 3410
Query: 3624 -WIDQERSWAVATLKIALP---SLYQTLCFEDAAL----WRTYYN------NSMCEQEFP 3669
W+ +A L+ + P L Q + ++ + TY N S + E
Sbjct: 3411 PWLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDK 3470
Query: 3670 SILAKK-----------VSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLK 3718
+ +K +S F ++++++ + +++ A+ F + LG + + P++L
Sbjct: 3471 HMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLP 3530
Query: 3719 RLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECA 3778
LY++ P++ I+S G+DP Q A E +++GQGQ +A +M+K+
Sbjct: 3531 TLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAM 3590
Query: 3779 RNGDWLCLKNLHLVVSWLPVLEKELNTLQP-----KDTFRLWLTAEVHPNFTPILLQSSL 3833
++G+W+ L+N HL VSW+ +E+ + T KDTFRL+L++ F +LQ+S+
Sbjct: 3591 KSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSV 3650
Query: 3834 KITYESPPGLKKNLMRTYESWTPEQISKKDNTHR-AHALFSLAWFHAACQERRNYIPQGW 3892
K+T E P GL+ N+ R + TP + + +F + +FHA QER+ + P GW
Sbjct: 3651 KVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGW 3710
Query: 3893 TKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLK 3952
YEF+ SD + +L+ + W+ + + YGGR+ + +D R L++ LK
Sbjct: 3711 NICYEFNDSDRECALLNL-KLYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILK 3769
Query: 3953 QFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARS 4012
+FF+ ++ + ++ I+ P + S+ +++ IE +P D P FG+ N
Sbjct: 3770 RFFSPETLEEDYKYSESGIY----FAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLV 3825
Query: 4013 SQRMISSQVISQ-LRILGRSITAG-SKFDREIWSNELSPV-LNLWKKLNQNSNLIHQKVP 4069
Q +S +I+ L + RS T G K + EI ++ V + +KL V
Sbjct: 3826 FQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVK 3885
Query: 4070 PPNDRQGSPILSFII---LEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALL 4126
R S L+ ++ +++FN L++ +H SL L+K I G ++S E++K+ ++ L
Sbjct: 3886 DLQGRLNS--LTTVLGQEVDRFN--NLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFL 3941
Query: 4127 NQKCPLAWQSKWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDT 4185
N + P W + PL +++ L+ R + W+ + + ++ +S F P
Sbjct: 3942 NNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYW-----ISGFFFPQG 3996
Query: 4186 FLNALRQETARAVGRSVDSLKF----VASWKGRL------------QEAKLQIKI----S 4225
FL Q AR +D L F + +++ + QE + +++
Sbjct: 3997 FLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPED 4056
Query: 4226 GLLLEGCSFDGNQLSENQLD-----SPSVSSVLPCFMGWIPQDACGPYSPDECI-SLPVY 4279
G+L+ G D ++ + ++ ++ VLP + + PQ Y P + P+Y
Sbjct: 4057 GVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLP-VVHFEPQQ---NYKPSPTLYHCPLY 4112
Query: 4280 ----------TSAERDRVVTNIDVPCGGNQDQWIQCGAAL 4309
T+ V + +P ++D WI G+AL
Sbjct: 4113 KTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSAL 4152
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 1268 bits (3282), Expect = 0.0
Identities = 963/3475 (27%), Positives = 1667/3475 (47%), Gaps = 308/3475 (8%)
Query: 1021 MMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSA 1080
+ E H+ +IK++IE + +K R + + +ELE + + ++ D+ + ++
Sbjct: 666 IFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRY------- 718
Query: 1081 KLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKD--------------IES 1126
+K+ +I L++ K+ F EE F S+ E+
Sbjct: 719 --LKKAQILNGKLDLAADKI----EQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYET 772
Query: 1127 CAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEE--HS-----VM 1179
+ + Y + +G N D + E + N+ L K+E+ H M
Sbjct: 773 AVEFSSNYRAWTEGPYHKVNPDQV---------EADIGNYWRGLYKLEKTFHDSPYALAM 823
Query: 1180 TVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADT 1239
T K++S+V+ +K IP+++ + L P HW + ++G P S + + L +
Sbjct: 824 TKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEP 883
Query: 1240 IVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIV 1299
+ + + ++ A E ++ +A+ ++ F + Y ++ + + + + + ++
Sbjct: 884 YIDR---FEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLL 940
Query: 1300 NQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGR- 1358
+ D+ Q+++ SP+ K +E ++ WE KL L E L +Q W+YLEPIF
Sbjct: 941 D---DHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSP 997
Query: 1359 ---GALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSL 1415
+P+E RF VD+ +R IM + +D V T+ T + L + L+ K L
Sbjct: 998 DIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGL 1057
Query: 1416 NEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITA 1475
NE+LE+KR FPRF+F+ +D+LLEIL ++ +P+ +Q HLKK F GI V F E + IT
Sbjct: 1058 NEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTE-TLDITH 1116
Query: 1476 MKSLEGEVVPFKNKVPLSN---NVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPS 1532
MKS EGEVV + + VE WL +L M ++ ++ + +
Sbjct: 1117 MKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVR 1176
Query: 1533 LFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNI-DTSSEDPGNTESGI 1591
+P Q + QI +T++V+ AI + LEQY + +D G
Sbjct: 1177 DWPGQTVLCVSQIFWTKEVQTAIP---------MGIKALEQYLKTCNRQIDDIVTLVRGK 1227
Query: 1592 LELK----LKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCCVQMVDS 1647
L ++ L AL++ +H DV+ L + + D+ W QLR+Y + +H +M+++
Sbjct: 1228 LSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLE-TKMINA 1286
Query: 1648 EFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLG 1707
+Y YEY GN+ +LV TPLTD+CY TL A+ + LGG P GPAGTGKTE+ K L +
Sbjct: 1287 GLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVA 1346
Query: 1708 RQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKN 1767
+Q +VFNC +G+D ++G+ F GL+ CGAW CFDEFNR++ VLS V+ QI TIQ +
Sbjct: 1347 KQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINA 1406
Query: 1768 HRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAE 1827
+ G E++++ +FITMNP GY GR +LPDNLK LFR VAM PD +IAE
Sbjct: 1407 GADILMFEGTELKLDPTCAVFITMNP---GYAGRSELPDNLKALFRTVAMMVPDYAMIAE 1463
Query: 1828 VILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSG 1887
++LYS GF A+ LS K+VA + L E L+ Q HYD+G+RA+K+VL +GNL +
Sbjct: 1464 IVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY---- 1519
Query: 1888 TTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVF 1947
N NE ++++++ + KF D F+ + D+FPG++L + +Y++L AA+K
Sbjct: 1520 --PNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNC 1577
Query: 1948 EEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAAL---CKTGKV-- 2002
N ++ +K L++YE + R G +IVG GK++ +R+L AL C+ G +
Sbjct: 1578 ASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEE 1637
Query: 2003 --VKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDP 2060
V+ +NPK++ QL G D + EWSDGVL S R W+I DG +D
Sbjct: 1638 NKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDA 1697
Query: 2061 EWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEET 2120
WIE++N+VLDDN+ L + SGE IQ P +N +FE DL ASPAT+SR GMI++
Sbjct: 1698 VWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHML 1757
Query: 2121 DLNSLIKSWLRNQPAEYRNNLENWIGDYFEK----ALQWVLKQNDYVVETS---LVGTVM 2173
L+ SW+ PA + +I F++ +++++ K + TS LV ++M
Sbjct: 1758 GWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLM 1817
Query: 2174 NGLS----------HLHGCRDHDE-------FIINLIRGLGGNLNMKSRLEFTKEVFHWA 2216
N + L D + F+ +LI +G + RL+F K +
Sbjct: 1818 NLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNK-ILREL 1876
Query: 2217 RESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLP------VIQTPDMQR 2270
ESP D TR T+ L+ + T+ S LT+P + +
Sbjct: 1877 MESPIS---------DRTRN---TFKLQSGTEQTS---SKALTVPFPEKGTIYDYQFVTE 1921
Query: 2271 GLDYFKPWLSS---------------------DT-------------KQPFILVGPEGCG 2296
G+ ++PW+ DT ++P I VGP G G
Sbjct: 1922 GIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTG 1981
Query: 2297 KGMLL-RYAFSQLRST--QIATVHCSAQTTSRHLLQKLSQTCMVISTNTGR----VYRPK 2349
K + + + +QL + ++ SAQTT+ +QT ++ + + V+ P
Sbjct: 1982 KSVYITNFLLNQLNKEIYKPLLINFSAQTTA-------AQTQNIVMSKLDKRRKGVFGPP 2034
Query: 2350 DCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD-ENLEWVGLENIQIVASMSA 2408
+R+V+++ D+N+P + +G + L+Q L + +YD ++ + L +IQI+ +M
Sbjct: 2035 LGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGP 2094
Query: 2409 GGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYL 2468
G GR+ +T R+ + +I+ + + TI+ L L K + + +
Sbjct: 2095 PGG-GRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTT-QI 2152
Query: 2469 LAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVA 2528
+ G+M E ++ SHY F ++ + G+ L + + + +
Sbjct: 2153 VNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVC---LSRPETTETTEVIKRLWV 2209
Query: 2529 YEARRLFRDKIVGAKE----LHLFDIILTSVFQGDWGS--DILDNMSDSFYVTWGARHNS 2582
+E R++ D+++ + ++ IL + D+ LD +D R
Sbjct: 2210 HEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLM 2269
Query: 2583 GARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQN-LDILLFHEVLEYMSRID 2641
+ + + + +++ L+ +++ L Y ++ ++++LF +E++SRI
Sbjct: 2270 FCDFHDPKREDTNYREIADVDN--LRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRIS 2327
Query: 2642 RVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLA 2701
R+L P LL G G GR+++T L +HM +F +IS+GY+ ++ DLK +L+
Sbjct: 2328 RILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKC 2387
Query: 2702 GIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLK------DQA 2755
Q V L D Q +FLE +++LL++GE+P L+ L+E + + ++ D+
Sbjct: 2388 AEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKT 2447
Query: 2756 SQ-DGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNS 2814
Q DG +FN F + LH+VL M F PAL C + W + W
Sbjct: 2448 KQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPED 2507
Query: 2815 SMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMT 2874
+++ + E E+ D K ++ D KSF + E + TP+ Y+
Sbjct: 2508 ALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFV--ELQRYNYVTPTSYLE 2565
Query: 2875 FLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADA 2934
+ + + K+ E++K + + G+ KL+ A + V + + LK E D
Sbjct: 2566 LISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDE 2625
Query: 2935 ALQMITVSMQDASEQKTE-LERLKHRIA-EEVVKIEERKNKIDDELKEVQPLVNEAKLAV 2992
MI + + KTE + + IA E+ + + K++ D +L P++ A A+
Sbjct: 2626 --MMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAAL 2683
Query: 2993 GNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGI--------------FDTSWVSMKSFL 3038
+ + ++ ++S++ PP ++ ++E + L GI + W K L
Sbjct: 2684 DTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLL 2743
Query: 3039 AKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQ 3098
+ + +D NI + + N F P+ + ASTAA L WV A
Sbjct: 2744 GDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNP-DFVPEKIRNASTAAEGLCKWVIAMDS 2802
Query: 3099 YSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKL 3158
Y V + + P + + A E LK D RK + L V K++ L++ + + A L
Sbjct: 2803 YDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADL 2862
Query: 3159 EAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAP 3218
E +V + ++ AE LI L E RW+ +E+ + L +++ + YL A
Sbjct: 2863 ENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFT 2922
Query: 3219 ESLRKTCLEEWT---KSAGLEKFDLRRFLCTESEQLI---WKSEGLPSDDLSIENALVIL 3272
+ R+ +EWT K + D + T E + W GLPSD SI+N ++I+
Sbjct: 2923 STYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIM 2982
Query: 3273 QIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLI 3332
+R P +IDP SQA +W+K K + L VI + +++ LE ++FG ++
Sbjct: 2983 N-------ARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVL 3035
Query: 3333 IQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAA 3391
++ + + ++P+L PLL + QG +++GD I+Y +FR +++T+ NP P+ +
Sbjct: 3036 LENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETS 3095
Query: 3392 SIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETL 3451
VT +NF T G++ QLL + + E+PDLEE+K L+ Q + K QL ++E+ +LE L
Sbjct: 3096 VKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVL 3155
Query: 3452 ATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYF 3511
++S+GNILE++ I+ L+ +KA + I + + + + + +D R Y P+A +S ++F
Sbjct: 3156 SSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFF 3215
Query: 3512 IISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLF 3571
++DL+ I MY++SL F+ LF +++N + SE +R+Q L + +Y +CR LF
Sbjct: 3216 SLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLF 3275
Query: 3572 KADQLMFALHFVRG--MHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQER 3629
+ D+L+F+ +H + EW +G D+ L +W+ Q +
Sbjct: 3276 EKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIG-----LDNPYA---NLCTWLPQ-K 3326
Query: 3630 SWAVATLKIALPSLYQTLCFEDAAL---WRTYYNNSMCEQE-FPSILAKKVSLFQQILVV 3685
SW LP+ ++T+ E L W+ Y++ E FP K + FQ++L++
Sbjct: 3327 SWDEICRLDDLPA-FKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLII 3385
Query: 3686 QALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQ 3745
+ LRPD++ + F LG + P P +L + + ++ P++ ++SPGADP L
Sbjct: 3386 RCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALL 3445
Query: 3746 ELANAE-RSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELN 3804
+ A+ + G +++GQGQ +A++ML++ + G W+ L+N HL SW+P LEK
Sbjct: 3446 KFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCE 3505
Query: 3805 TLQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTY---ESWTPEQ 3858
L P+ T FR+WLT+ PNF +LQ+ +K+T E+P GL+ N++R+Y PE
Sbjct: 3506 ELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEF 3565
Query: 3859 I-SKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA 3917
S K L+ L +FHA QERR + P GW YEF+ +DLR + +
Sbjct: 3566 FGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQY 3625
Query: 3918 KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVS 3977
+++ +E + + YGGR+ + +D R L+S L +FFN +++ + + S +
Sbjct: 3626 EELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYF--- 3682
Query: 3978 LPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRIL-GRSITAGS 4036
+P S Y + +P P FG+ AN + + + + + + RS AG+
Sbjct: 3683 VPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGA 3742
Query: 4037 KFDREIWSNELSPVLNLWKKLNQNSNL--IHQKVPPPNDRQGSPILSFIILEQFNAIRLV 4094
K E+ + S +L KL N ++ ++ P + + +L + E +L+
Sbjct: 3743 KSSDEVVNEVASDILG---KLPNNFDIEAAMRRYPTTYTQSMNTVL---VQEMGRFNKLL 3796
Query: 4095 QSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPL-QYLRGLVA 4153
+++ S + K I+G ++S++++++ S++LN K P W K PL Y+ +A
Sbjct: 3797 KTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLA 3856
Query: 4154 RALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF---VAS 4210
R +Q W + LS F FL +Q AR +D L F V
Sbjct: 3857 RLKFLQQWYEVGPPPVFW-----LSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVME 3911
Query: 4211 WKGRLQEAKLQIKISGLLLEGCSFDG--NQLSENQ----LDSPSVSSVLPCFMGWIPQDA 4264
K + + I GL L+G S++ +L+E+ D+ V + PC IP+
Sbjct: 3912 DKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPK-- 3969
Query: 4265 CGPYSPDECISLPVYTSAERDRVVTN----------IDVPCGGNQDQWIQCGAAL 4309
P+Y ++ER V++ + +P ++ WI G AL
Sbjct: 3970 ------RPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVAL 4018
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 1251 bits (3238), Expect = 0.0
Identities = 958/3548 (27%), Positives = 1669/3548 (47%), Gaps = 261/3548 (7%)
Query: 894 KEVERL-PSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEA 952
+EV RL P V + I+ P K + ++I++ L L + L +D F+ ++
Sbjct: 1070 EEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKS 1129
Query: 953 MEVLTIMPQSVEEIGDANLQ--YSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETI-- 1008
L + + G + ++ER+ +F+ + LL+T ET+
Sbjct: 1130 ESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFK 1189
Query: 1009 --SNLKAKWDKFELMMESHQLMIKDQIEVMKGN----VKSRLQIYYQELEKFKARWDQLK 1062
L KW+ + + + +K Q+ ++ N ++ R + E ++F W+Q
Sbjct: 1190 QLEELPEKWNNIKKVA----ITVKQQVAPLQANEVTLLRQRCTAFDAEQQQF---WEQFH 1242
Query: 1063 PGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISK 1122
H +++ + IE +E T + + F + P++ K
Sbjct: 1243 KEAPFRFDSIH-----PHQMLDARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRK 1297
Query: 1123 DIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFE--EFLMNWHDRLRKVEEHSVMT 1180
++ ++W W + E +F + + ++V T
Sbjct: 1298 EVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFT 1357
Query: 1181 VKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLG----LPRGTSLEKLLFGDLLRV 1236
L+S V + + ++ + HW L + G + + T+L LL L
Sbjct: 1358 -GLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHY 1416
Query: 1237 ADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWK 1296
D +++ + +A E+ + + L+EL G F YE + L+ +
Sbjct: 1417 ED-------EVRGIVDKAAKEMGMEKTLKELQTTWAGMEF---QYEPHPRTNVPLLCSDE 1466
Query: 1297 DIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIF 1356
D++ + DN+ LQ+L S Y F ++VS W++KL+ +D + +QR W +LE IF
Sbjct: 1467 DLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIF 1526
Query: 1357 G-----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRC 1411
R LP++ RF +D DF+ + D +K V T G+ L I +L C
Sbjct: 1527 TGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLC 1586
Query: 1412 QKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFD---- 1467
+K+L E+L+ KR AFPRFYF+ DLL+IL T P +Q HL KLF + + F
Sbjct: 1587 EKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDAS 1646
Query: 1468 -EKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQ 1526
E +K M S E E V F S VE WLN + MK T+ + E VT
Sbjct: 1647 GEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKP 1706
Query: 1527 GAVDPSLFPSQILCLAEQIKFTEDV-----------ENAIKDH---SLHQIETQLVNKLE 1572
P+Q+ QI +T +V E+A+KD+ + Q++T + +
Sbjct: 1707 REQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIG 1766
Query: 1573 QYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF 1632
Q + D K+ + +H DVV ++ +V + + W QLR
Sbjct: 1767 QLSKGDRQ--------------KIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRH 1812
Query: 1633 YMKSD-HTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPA 1691
+ C + D++F Y+YEY GN +LV TPLTD+CY+TLTQ++ + + G P GPA
Sbjct: 1813 RWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPA 1872
Query: 1692 GTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVL 1751
GTGKTE+ K LG LG V VFNC E +D KS G I+ GL + GAWGCFDEFNR+ VL
Sbjct: 1873 GTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVL 1932
Query: 1752 SAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQL 1811
S V++Q+++IQDA+++ + LG+E+ +N + GIFITMNP GY GR +LP+NLK L
Sbjct: 1933 SVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNP---GYAGRTELPENLKSL 1989
Query: 1812 FRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKT 1871
FRP AM PD ELI E++L +EGF +A+ L+RK + ++ L +ELL+ Q HYDWGLRA+K+
Sbjct: 1990 FRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKS 2049
Query: 1872 VLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIEL 1931
VL +G+L R + E +++++LR + K D F LI D+FP +++
Sbjct: 2050 VLVVAGSLKR------GDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDV 2103
Query: 1932 KEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRM 1991
A +++ + + N + K ++L E L R V +VG +G GKS + R
Sbjct: 2104 PRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRS 2163
Query: 1992 LRAALCKTGKVVKQ----YTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQD 2047
L KT +++K+ +NPKA+ +L G I+ T EW DG+ ++ R++ D
Sbjct: 2164 LH----KTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHD 2219
Query: 2048 VSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATI 2107
WI+ DGDIDP WIESLN+V+DDN++LT+ S ERI P + +FE L A+PAT+
Sbjct: 2220 GPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATV 2279
Query: 2108 SRMGMIFLSDEETDLNSLIKSWLRNQPAE-YRNNLENWIGDYFEKALQWV---LKQNDYV 2163
SR G+++++ + N + SW+ + + R NL Y L + K+ +
Sbjct: 2280 SRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPI 2339
Query: 2164 VETSLVGTVMNGLSHLHGCRD----------HDEFIINLIRGLGGNLNMKSRLEFTKEVF 2213
E S+V V + L L D F+ I GG + +++ E
Sbjct: 2340 PEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFS 2399
Query: 2214 HW-----ARESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDM 2268
W P D Y D + + P+ D L ++ T +
Sbjct: 2400 KWWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQ--FEFDPEMPLQACLVHTSET 2457
Query: 2269 QRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQL--RSTQIATVHCSAQTTSRH 2326
R + YF L + ++P +LVG G GK +L+ + L + + V + TTS
Sbjct: 2458 IR-VCYFMERLMA-RQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAM 2515
Query: 2327 LLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQG 2386
L L + + GR Y P ++L+ ++ D+N+P++D +GT ++Q L Y
Sbjct: 2516 LQAVLEKP---LEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGH 2572
Query: 2387 FYDEN-LEWVGLENIQIVASM--SAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYG 2443
+YD + L + N+Q V+ M +AG +L F+ V + +P + L +IY
Sbjct: 2573 WYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFV----LSFPGADALSSIYS 2628
Query: 2444 AYLEPVLHKNLKNHSIWGSSSK-IYLLAGSMVQVYEQVRAKFTVDDYS-HYFFTPCILTQ 2501
+L ++LK + S K I L + ++++ F HY F
Sbjct: 2629 I----ILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFAN 2684
Query: 2502 WVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWG 2561
G+ +E S L + + +E+ R++RDK+V K+ LFD I T V +
Sbjct: 2685 IFQGILFSSVECVKSTWDL---IRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLK---- 2737
Query: 2562 SDILDNMSDSFYVTWGARHNSGARAAPGQP--LPPHGKPLGKLNSTDLKDVIKKGLIHYG 2619
D++ D T G+P +P L L + + L ++
Sbjct: 2738 -KTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWEL-------LTQTLVEALENHN 2789
Query: 2620 RDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSP 2679
N +D++LF + + ++ I+R+L P G+ LL G G G++++T L + + +F
Sbjct: 2790 EVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQI 2849
Query: 2680 KISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLY 2739
+ +GY+++ FK DL + AG++ V L+ D Q FL +IN LL+SGE+P LY
Sbjct: 2850 TLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLY 2909
Query: 2740 TLEELEPLLLPLKDQASQDGFFG---PVFNYFTYRIQQNLHIVLIMDSANSNFMINCESN 2796
+ +E+E ++ ++++ G + +F RI++ L + L + +
Sbjct: 2910 SDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKF 2969
Query: 2797 PALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFL 2856
PA+ + W W +++ + T G E K S+
Sbjct: 2970 PAIVNCTAIHWFHEWPQQALESVSLRFLQNTEG---------IEPTVKQSISKFMAFVHT 3020
Query: 2857 LIHESCKAY--------GATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAK 2908
++++ ++Y TP ++ F+ +Y ++ +KEL + L+ G+ KL+
Sbjct: 3021 SVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTS 3080
Query: 2909 ALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIE 2968
A VD+L K Q V LK K ++AD +Q++ V S +K + + ++A +++++
Sbjct: 3081 AQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 3140
Query: 2969 ERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMG--- 3025
+++ +++L + +P + A+ A+ + +L+E++S PP + ++ V+ LM
Sbjct: 3141 QKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRG 3200
Query: 3026 --IFDTSWVSMKSFLAK-RGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRA 3082
D SW + K +AK G + + F+ NI + +++ L F+P+
Sbjct: 3201 RVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYL--QDPEFNPEFVATK 3258
Query: 3083 STAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVS 3142
S AAA L +WV +++ V + P ++L +++ ++ + + + ++
Sbjct: 3259 SYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLA 3318
Query: 3143 ELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPK 3202
+L +F+ T++ K + E TI A L+ L E+ RW V ++ TL
Sbjct: 3319 KLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCG 3378
Query: 3203 RAQLAAAFITYLSAAPESLRKTCLEE-W--------TKSAGLEKFDLRRFLCTESEQLIW 3253
L AFI+YL + R++ L+ W T D R L +++ W
Sbjct: 3379 DILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAW 3438
Query: 3254 KSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKT-HLKDSRLEVINQ 3312
++EGLP+D +S+ENA + +I + W P ++DP Q +W+K + +D R+ I Q
Sbjct: 3439 QNEGLPADRMSVENATI---LINCERW----PLMVDPQLQGIKWIKNKYGEDLRVTQIGQ 3491
Query: 3313 QDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNE 3371
+ ++ +E A+ G ++I+ + + ++PVL PLL R+++ +G ++IGDK +YN
Sbjct: 3492 K--GYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RFIKIGDKECEYNP 3547
Query: 3372 EFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQ 3431
+FRL L T+ NP P+ + T +NFT TR GL QLLA + E+PDLE+ K+ L +
Sbjct: 3548 KFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTK 3607
Query: 3432 QEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQIS 3491
Q+ KI L LE+SLL L+++ GN L L+E+L TK ++A +++ ++E+ ++
Sbjct: 3608 QQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVK 3667
Query: 3492 LDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRI 3551
+++ R+ Y P A AS +YFI++DLSKI+ MY+FSL AF +FQ+A++ E+ +R+
Sbjct: 3668 INEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERV 3727
Query: 3552 QSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKA 3611
+LI S+ VY+Y R LF+ D+L + FQ + V D L ++
Sbjct: 3728 ANLIDSITFSVYQYTIRGLFECDKLTYLAQLT-------FQILLMNREVNAVELDFLLRS 3780
Query: 3612 DSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFE---DAALWRTYYNNSMCEQEF 3668
Q P ++W + ++ + L + A W+ + + E+E
Sbjct: 3781 PVQTGTAS--PVEFLSHQAWGAVKVLSSMEE-FSNLDRDIEGSAKSWKKFVESECPEKEK 3837
Query: 3669 PSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIE 3728
K + Q++ +++A+RPDR+ A+ F + LG K V L+ ++E+
Sbjct: 3838 LPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPAT 3897
Query: 3729 PILIIISPGADPSQELQELANA---ERSGECYHQVAMGQGQADLAIQMLKECARNGDWLC 3785
P+ I+SPG DP ++++ + + +H V++GQGQ +A L A+ G W+
Sbjct: 3898 PMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVI 3957
Query: 3786 LKNLHLVVSWLPVLEKEL--NTLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYE 3838
L+N+HLV WL LEK+L ++ FR++++AE P+ +L++S+KIT E
Sbjct: 3958 LQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNE 4017
Query: 3839 SPPGLKKNLMRTYESWTPEQISK-KDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYE 3897
P G+ NL + +++T + + T LF+L +FHA ERR + PQGW + Y
Sbjct: 4018 PPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYP 4077
Query: 3898 FSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNS 3957
F+ DL N++ + V ++ + L +YGG I + +D R+ ++YL +F
Sbjct: 4078 FNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRP 4137
Query: 3958 SVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARS 4012
+++ + S+ P LP + Y I+ + P +GL N + ++
Sbjct: 4138 EMLE-----GELSLAP-GFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQT 4191
Query: 4013 SQRMISSQVISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPN 4072
S+++ + + Q R AG+ + ++ + + + +++ N I + +
Sbjct: 4192 SEKLFRTVLELQPRDSQARDGAGATREEKV----KALLEEILERVTDEFN-IPELMAKVE 4246
Query: 4073 DRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPL 4132
+R +++F + N L + + +SL L ++G ++S ++ L +AL P
Sbjct: 4247 ERTPYIVVAFQECGRMNI--LTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPE 4304
Query: 4133 AWQSK-WEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALR 4191
+W + + + L+ R ++ W + T+ L+ F+P +FL A+
Sbjct: 4305 SWARRAYPSTAGLAAWFPDLLNRIKELEAWTG----DFTMPSTVWLTGFFNPQSFLTAIM 4360
Query: 4192 QETARAVGRSVDSLKFVASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQLSENQLDS 4246
Q TAR +D + + +E + I GL +EG +D +
Sbjct: 4361 QSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKL 4420
Query: 4247 PSVSSVLP-CFMGWIPQDACGPYSPDECISLPVYTSAER-DRVVTNIDVPCGGNQDQWIQ 4304
++ +P F+ IP D S C PVY +++R V ++ N +W+
Sbjct: 4421 KDLTPPMPVMFIKAIPADKQDCRSVYSC---PVYKTSQRGPTYVWTFNLKTKENPSKWVL 4477
Query: 4305 CGAALFLK 4312
G AL L+
Sbjct: 4478 AGVALLLQ 4485
Score = 45.4 bits (106), Expect = 0.001
Identities = 46/280 (16%), Positives = 119/280 (42%), Gaps = 18/280 (6%)
Query: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486
L++RP ++++ + L+ + R+ + + P+ KN+ V +
Sbjct: 553 LLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVH-KNMPTVAGGL 611
Query: 487 VWVRQLELKVDDTI----KIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542
W ++L ++ +I + G R Q +D+L L+ YE ++DW R +
Sbjct: 612 RWAQELRQRIQGPFSNFGRITHPCMESAEGKR-MQQKYEDMLSLLEKYETRLYEDWCRTV 670
Query: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQ 602
S+ L S +++ D + ++++ +L+ +L+E+ L +
Sbjct: 671 S---EKSQYNL----SQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAA 723
Query: 603 VANIAQKFCKQAII-LKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661
++ F +Q + L+ +A++YN + + +++ + P++ + + ++ ++ K+
Sbjct: 724 AMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKT 783
Query: 662 QITWDNPKELEGYI----QKLQNAAERLATENRKLRKWHT 697
+ D E+ I Q++Q + + ++ W T
Sbjct: 784 EGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVT 823
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 1233 bits (3189), Expect = 0.0
Identities = 969/3728 (25%), Positives = 1727/3728 (46%), Gaps = 316/3728 (8%)
Query: 773 PEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFI----GIPNQFKGVGE----AGDESI 824
P +DL + + P E+ A + I +P K V E +GD +
Sbjct: 657 PLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLL 716
Query: 825 FSIMIDRNASGFL--TIFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKH----LFT 878
S+ + L TI S L A ++++++ + D+ + ++ + L
Sbjct: 717 ESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLA 776
Query: 879 VHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDD----LIQKLFDLLVLSL 934
E L+ K LPS++ + IN + VK + L + D+L +L
Sbjct: 777 QEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNL 836
Query: 935 KKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQER----KPEILPLFQEA 990
K + + E + + E P S+EE+ + + ER + I+ + +
Sbjct: 837 HKEVDSICEEFRSISRKIYE----KPNSIEELAELREWMKGIPERLVGLEERIVKVMDDY 892
Query: 991 EDKNRLLRTVAGGGLET---ISNLKAK-WDKFELMMESHQLMIKDQIEVMKGNVKSRLQI 1046
+ + L ++ SN +K + EL+ + H ++D+ + K + +
Sbjct: 893 QVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQH---VEDEEKFRKIQIMDQNN- 948
Query: 1047 YYQELEKFKARWDQLKPGDDV-IETGQHNTLDKSAKLIKEKKIEFDDLEV---TRKKLVD 1102
+ ++LE + + G + +E + + + + +K++ + L + R+++
Sbjct: 949 FQEKLEGLQL----VVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERI-- 1002
Query: 1103 DCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITF---RTKTYLF 1159
F L N+ S + K+ + +W ++ + + N+ + + +
Sbjct: 1003 ----FSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVV 1058
Query: 1160 EEFLMNWHDRLRKVEEHSV---MTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRL 1216
E F H +++ ++ + + +++ ++++K IP+++ +R + HW L
Sbjct: 1059 EAF-KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQ 1117
Query: 1217 LGLPRGTSLEKLLFGDLLRV--ADTI--VAKAADLKDLNSRAQGEVTIREALRELDLWGV 1272
+ + L F L + D I ++K A++ A E I +AL +++
Sbjct: 1118 INI-NVRPKANLTFARCLEMNLQDHIESISKVAEV------AGKEYAIEQALDKMEKEWS 1170
Query: 1273 GAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKL 1332
+F ++ Y+ + + +K + +++ D+ + Q++ SPY K FE +++ WE KL
Sbjct: 1171 TILFNVLPYKATDTYILKSPDEASQLLD---DHIVMTQNMSFSPYKKPFEQRINSWENKL 1227
Query: 1333 AELDEYLQNLNHIQRKWVYLEPIFG----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRV 1388
E L+ + QR W+YLEPIF LP E R+ ++ ++ IM + ++ V
Sbjct: 1228 KLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREV 1287
Query: 1389 TTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPS 1448
+ + + +SL L QK L+E+LE KRSAFPRFYF+ DD+LLEIL Q+ +P+
Sbjct: 1288 INVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPT 1347
Query: 1449 VIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMK 1508
+Q HL+K F I + F E + IT M S EGE V + S+NVE WL ++ MK
Sbjct: 1348 AVQPHLRKCFENIARLLFQEDLE-ITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMK 1406
Query: 1509 KTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSLH-QIETQL 1567
++ ++++ + + +P Q+ Q +T +V A++ +L Q+ QL
Sbjct: 1407 ASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQL 1466
Query: 1568 VNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWK 1627
+L + S + L ALI+ +H DVV +L Q V + D+ W
Sbjct: 1467 CQQLSDLVALVRGKL------SRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWI 1520
Query: 1628 KQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNP 1687
QLR+Y +++ ++ V++EF Y YEY GN+ +LV TPLTD+CYLTLT A+ + GG P
Sbjct: 1521 SQLRYYW-TNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAP 1579
Query: 1688 YGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLE 1747
GPAGTGKTE+ K LG L Q +VFNC + +D +MG+ F GL GAW CFDEFNR++
Sbjct: 1580 AGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRID 1639
Query: 1748 ESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDN 1807
VLS V+ QI TIQ A + G E+ + + +FITMNP GY GR +LPDN
Sbjct: 1640 IEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNP---GYAGRTELPDN 1696
Query: 1808 LKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLR 1867
LK LFRPVAM PD +I E+ LYS GF +A VL++K+ F LS E L+ Q HYD+G+R
Sbjct: 1697 LKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMR 1756
Query: 1868 ALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFP 1927
A+KTV+ +GNL R+ + NE I ++A+R + KF D F ++ D+FP
Sbjct: 1757 AVKTVISAAGNLKRE------NPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFP 1810
Query: 1928 GIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKST 1987
I+ ++ +Y L A+++ +N + + + K ++LYE R G+++VGP+G+GKST
Sbjct: 1811 TIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKST 1870
Query: 1988 LWRMLRAALCKTG----------KVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNS 2037
+R+L AA+ + V Y +NPK++ QL G D+ T EW+DG+ ++
Sbjct: 1871 CYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSF 1930
Query: 2038 ARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETH 2097
R W + DG +D WIE++N+VLDDN+ L + SGE I+ + +FE
Sbjct: 1931 IRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQ 1990
Query: 2098 DLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPA---EYRNNLENWIGDYFEKALQ 2154
DL+ ASPAT+SR GM++L L I+ WLR P Y + + + E+++
Sbjct: 1991 DLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESIS 2050
Query: 2155 WVLKQNDYVVETSLVGTVMNGLSHL----------HGCRDHDE-------------FIIN 2191
+V V+ ++ M+ L L G + FI +
Sbjct: 2051 FVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFS 2110
Query: 2192 LIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKPM----------------------DT 2229
LI +G + R F+ HW R + + D+
Sbjct: 2111 LIWSVGATGDSSGRTSFS----HWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDS 2166
Query: 2230 YYDSTRGRLATYVL----KKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQ 2285
+ + +V P + D + +P + T M LD + K+
Sbjct: 2167 EDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLD-----MLLTNKK 2221
Query: 2286 PFILVGPEGCGKGM------LLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVIS 2339
P + +GP G GK + L A + + SA T + KL +
Sbjct: 2222 PVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDK------ 2275
Query: 2340 TNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENL--EWVGL 2397
V+ P + ++ D+N+P L+ +G + L+Q + + G+YD + + L
Sbjct: 2276 -RRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNL 2334
Query: 2398 ENIQIVASMSAGGRLGRHKLTTRFT---SIVRLCSIDYPEREQL-QTIYGAYLEPVLHKN 2453
+I V +M G GR+ +T R + + +D ++++ TI G +L+ +L +
Sbjct: 2335 VDINFVCAMGPPGG-GRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEK 2393
Query: 2454 LKNHSIWGSSSKIYL---LAGSMVQVYEQVRAKFT-VDDYSHYFFTPCILTQWVLGLFRY 2509
+ G+ + L + + VY + ++ SHY F L++ G+
Sbjct: 2394 SYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMA 2453
Query: 2510 DLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMS 2569
D L L + +E R+FRD++V ++ FD +L + W ++ N
Sbjct: 2454 DPAKVEDQVQL---LRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCME-QW--EVTFNKV 2507
Query: 2570 DSFY-VTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQ-NLDI 2627
F + +G + G+ + + K + VI++ + Y + N L +
Sbjct: 2508 CPFQPILYGDFMSPGSDVKSYELITSESK---------MMQVIEEYIEDYNQINTAKLKL 2558
Query: 2628 LLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYEL 2687
+LF + + ++ RI R L G+ LL G G GR ++T L SHM F ++S+ Y +
Sbjct: 2559 VLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGM 2618
Query: 2688 KQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPL 2747
++++D+K VL AG++ + L D Q + +FLE IN++L+SG++P LYT +E + +
Sbjct: 2619 SEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQI 2678
Query: 2748 LLPLKDQASQDGFFGPVFNY---FTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQ 2804
+ ++ + G N +T R++ N+H+VL M F P+L C
Sbjct: 2679 VSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCT 2738
Query: 2805 VLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHES--- 2861
+ W W ++K + + +E E ++ + ++ + IH+S
Sbjct: 2739 IDWFNEWPAEALKSVATVFLNEIPELESSQEEIQ-----------GLIQVCVYIHQSVSK 2787
Query: 2862 -CKAYGA--------TPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVD 2912
C Y A TP Y+ LH++S + KK EL ++ +++G+ KL V
Sbjct: 2788 KCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVA 2847
Query: 2913 ELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKN 2972
++ LL+ + ++ I V A E + ++ + + E+ K + +
Sbjct: 2848 KMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIAD 2907
Query: 2973 KIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGI------ 3026
+L E P ++ A ++ N+ ++E+R+++ PP ++ ++E V + GI
Sbjct: 2908 DAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVP 2967
Query: 3027 -------FDTSWVSMKSFLAKRG-VREDIATFDARNISKEIRESVEELLFKNKGSFDPKN 3078
D W K L G E + FD NI + ++++ + + F P
Sbjct: 2968 GEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI--DNEEFQPAT 3025
Query: 3079 AKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVG 3138
+ S A + WV+A +Y V + + P + +L T+ + ++ L V
Sbjct: 3026 IAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVE 3085
Query: 3139 QKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELA 3198
++ ++ K++ ++ +LE + + ++ + A LIN L E RW V + L
Sbjct: 3086 DGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLN 3145
Query: 3199 TLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFD------LRRFLCTESEQLI 3252
+ +AA F+ YL R + W K L L +
Sbjct: 3146 NISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRS 3205
Query: 3253 WKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQ 3312
W+ GLP+D LS+EN ++ +S+ IDP SQA +W+K KD+ L+V
Sbjct: 3206 WQIAGLPNDTLSVENGVI-------NQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKL 3258
Query: 3313 QDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNE 3371
D +F+ ++E A+RFGK +++ + + ++P L P+L + Q V+++GD +I Y+E
Sbjct: 3259 SDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHE 3318
Query: 3372 EFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQ 3431
+FR++++T+ PNP P+ ++ +T +NFT + SGL QLL + E+PDLEE K +L+
Sbjct: 3319 DFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLII 3378
Query: 3432 QEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQIS 3491
+ +L +E+ +L L++S+GN +++ +LI+ L +K +A IQ ++ + + +
Sbjct: 3379 SNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKD 3438
Query: 3492 LDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRI 3551
+D R Y+P+A ++F +SDL+ ++ MY++SL FL +F + N + ++N ++RI
Sbjct: 3439 IDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRI 3498
Query: 3552 QSLISSLQHMVYEYICRCLFKADQLMFA-LHFVRGMHPE-LFQENEWDTFTGVVVGDMLR 3609
++ L + +Y +CR LF+ +LMFA L VR M E ++EW +L
Sbjct: 3499 SNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRY--------LLS 3550
Query: 3610 KADSQQKIRDQLPSWIDQERSWAVATLKIALP--SLYQTLCFEDAALWRTYYNNSMCEQE 3667
+ P W+ +R+W LP S + + + + +R +++ +E
Sbjct: 3551 GGSISIMTENPAPDWL-SDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHRE 3609
Query: 3668 -FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLE 3726
P I + + FQ++LV++ LR D++ +AM F L + + P NL ++K++
Sbjct: 3610 PLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNS 3669
Query: 3727 IEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL 3786
P++ ++SPG DP+ +L + A + + +++GQGQ A M++ G W+
Sbjct: 3670 TTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFF 3729
Query: 3787 KNLHLVVSWLPVLEKELNTLQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGL 3843
+N HL SW+P LE+ + + P FRLWLT+ F +LQ+ K+T E P G+
Sbjct: 3730 QNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGV 3789
Query: 3844 KKNLMRTYESWTPEQISKKDNTHRAHA-LFSLAWFHAACQERRNYIPQGWTKFYEFSLSD 3902
+ NL+++Y S + ++ + L SL FH ERR + P G+ YEF+ D
Sbjct: 3790 RANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGD 3849
Query: 3903 LRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDV 3962
LR + + D D+ ++ + YGGR+ + +D R + + L+ F+N V+
Sbjct: 3850 LRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSP 3909
Query: 3963 FNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANI-ARSSQRMISSQV 4021
+ + I+ +P + + Y + I+ +P +D P FGL N +Q + +
Sbjct: 3910 EHSYSASGIYH---QIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALL 3966
Query: 4022 ISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNL--IHQKVPPPNDRQGSPI 4079
+ +++ +S +AGS+ EI + N+ K+ + NL + K P + + +
Sbjct: 3967 GTIIQLQPKSSSAGSQGREEIVEDVTQ---NILLKVPEPINLQWVMAKYPVLYEESMNTV 4023
Query: 4080 LSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWE 4139
L + E RL+Q + Q+L L K ++G ++SS+++ +A++L N P W +K
Sbjct: 4024 L---VQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAY 4080
Query: 4140 GPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAV 4198
PL ++ L+ R +Q W+ Q + +S F P FL Q AR
Sbjct: 4081 PSLKPLSSWVMDLLQRLDFLQAWI-----QDGIPAVFWISGFFFPQAFLTGTLQNFARKF 4135
Query: 4199 GRSVDSLKF-----VASWKGRLQEAKLQIKISGLLLEGCSFDGN--QLSENQLDSPSVSS 4251
S+D++ F + Q ++ I GL LEG +D QL+E+Q
Sbjct: 4136 VISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEM 4195
Query: 4252 VLPCFMGWIPQDACGPYSPDECISLPVY----------TSAERDRVVTNIDVPCGGNQDQ 4301
+ W+ + P+Y T+ V +++P Q
Sbjct: 4196 AVI----WLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRH 4251
Query: 4302 WIQCGAAL 4309
WI+ G AL
Sbjct: 4252 WIKRGVAL 4259
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 1187 bits (3072), Expect = 0.0
Identities = 943/3447 (27%), Positives = 1595/3447 (46%), Gaps = 314/3447 (9%)
Query: 1043 RLQIYYQELEKFKARWDQLKPGDDVIETGQ--HNTLDKSAKLIKEKKIEFDDLEVTRKKL 1100
RL+ Y++ELE F+ R +V+ T + HN ++K +L K F + E+ K+
Sbjct: 796 RLEGYHRELESFRKR--------EVMTTEEMKHN-VEKLNELSKNLNRAFAEFELINKEE 846
Query: 1101 VDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFE 1160
E+ + L ++ K+ Q+W+ EF +E N + + E
Sbjct: 847 ----ELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQ-IAE 901
Query: 1161 EFLMNWHDRLRKVEEHSVMTV------KLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLF 1214
E W + ++ S + ++ ++DK+K IPIL + HW +
Sbjct: 902 EIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQIS 961
Query: 1215 RLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGA 1274
++G + L L V K L+ + + A E ++ + L + L V
Sbjct: 962 EIVGYEIKPTETTCLSNMLEFGFGKFVEK---LEPIGAAASKEYSLEKNLDRMKLDWVNV 1018
Query: 1275 VFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAE 1334
F+ + Y D+ + + I D + +++ D+ Q++ SP+ K E + WE KL
Sbjct: 1019 TFSFVKYRDTDTNILCAIDDIQMLLD---DHVIKTQTMCGSPFIKPIEAECRKWEEKLIR 1075
Query: 1335 LDEYLQNLNHIQRKWVYLEPIFGR----GALPKEQTRFNRVDEDFRSIMTDIKKDNRVTT 1390
+ + L Q W+YLEPIF +P+E +F VD ++S+M+ KDNR+
Sbjct: 1076 IQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILV 1135
Query: 1391 LTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVI 1450
+ L L+ QK LN++LE+KR FPRF+F+ +D+LLEIL ++ +P +
Sbjct: 1136 AADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRV 1195
Query: 1451 QSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNN---VETWLNDLALEM 1507
Q HLKK F GI + F + + I M S E E VPF K+ +N VE WL ++
Sbjct: 1196 QPHLKKCFEGIAKLEFTDNLE-IVGMISSEKETVPFIQKIYPANAKGMVEKWLQ----QV 1250
Query: 1508 KKTLEQLLKECVTTGRSSQGAVDPS----LFPSQILCLAEQIKFTEDVENAIKDHSLHQI 1563
++ + ++E + G + V + +P Q++ I +T++V A+ +++L
Sbjct: 1251 EQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALAENTLLDF 1310
Query: 1564 ETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTED 1623
+ +++ Q + G SG L L AL + +H DVV +L++ +V D
Sbjct: 1311 LKKSNDQIAQIVQLVR-----GKLSSGA-RLTLGALTVIDVHARDVVAKLSEDRVSDLND 1364
Query: 1624 WAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGL 1683
+ W QLR+Y + VQ++ +E Y YEY GN+ +LV TPLTD+CY TL A+K+ L
Sbjct: 1365 FQWISQLRYYWVAKDVQ-VQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNL 1423
Query: 1684 GGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEF 1743
GG P GPAGTGKTE+ K L L +Q +VFNC +G+D K+MG+ F GL + GAW CFDEF
Sbjct: 1424 GGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEF 1483
Query: 1744 NRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQK 1803
NR+E VLS V+ QI +IQ A+ G E+ +N +FITMNP GY GR +
Sbjct: 1484 NRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNP---GYAGRAE 1540
Query: 1804 LPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYD 1863
LPDNLK LFR VAM PD LI E+ LYS GF D++ L++K+VA + L E L+ Q HYD
Sbjct: 1541 LPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYD 1600
Query: 1864 WGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIK 1923
+G+RA+K+VL +GNL + + NES ++++AL ++KF D F +I
Sbjct: 1601 YGMRAVKSVLTAAGNLKLKYPEE------NESVLLLRALLDVNLAKFLAQDVPLFQGIIS 1654
Query: 1924 DVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGA 1983
D+FPG+ L + +Y+ L ++ + +P I K +++YE + R G +IVG
Sbjct: 1655 DLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMG 1714
Query: 1984 GKSTLWRMLRAALCKTGKV-------VKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTN 2036
GK++ +++L AAL V+ +NPKA+ QL G D + EW DGVL N
Sbjct: 1715 GKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLAN 1774
Query: 2037 SARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFET 2096
+ R+ D WII DG +D WIE++N+VLDDN+ L + SGE IQ ++ +FE
Sbjct: 1775 AFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEP 1834
Query: 2097 HDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYF----EKA 2152
DL ASPAT+SR GMI++ + L S++ P+ + + D F +
Sbjct: 1835 ADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPC 1894
Query: 2153 LQWVLKQNDYVVETS--------------------------------------------- 2167
L++ +VV+TS
Sbjct: 1895 LEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGL 1954
Query: 2168 ----LVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDF 2223
LV TV G + + D F NLI G+ N ++ TK R S DF
Sbjct: 1955 FLFSLVWTVA-GTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDF 2013
Query: 2224 HKPMDTYYDSTRGRLAT---YVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLS 2280
+ + G T Y+ K+ E + A + L +P ++T R + K +L
Sbjct: 2014 Y-----FIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETA---RQSFFLKTYL- 2064
Query: 2281 SDTKQPFILVGPEGCGKGMLLRYAFSQL-RSTQIAT-VHCSAQTTSRHLLQKLSQTCMVI 2338
D + P + VGP G GK + L ++T + ++ SA+T++ +QT +I
Sbjct: 2065 -DHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSA-------NQTQDII 2116
Query: 2339 STNTGR----VYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDE-NLE 2393
+ R ++ P ++ V+++ D+N+P + +G + L+Q + + ++D+ +
Sbjct: 2117 MSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTT 2176
Query: 2394 WVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKN 2453
+ + ++ +V +M G GR+ +T RFT + + SI+ E + L I+ + ++ K
Sbjct: 2177 RLDIVDMLLVTAMGPPGG-GRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKG 2235
Query: 2454 LKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDY------SHYFFTPCILTQWVLGLF 2507
++L G M+ + + V+++ SHY F ++ + G+
Sbjct: 2236 F---------DVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVL 2286
Query: 2508 RYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLF--------------DIILT 2553
L + ++ + + +E R+F D+++ ++ +F I
Sbjct: 2287 ---LCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKV 2343
Query: 2554 SVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKK 2613
+ G + DN+ F+ G P TDLK +
Sbjct: 2344 LIHLSPTGKIVDDNIRSLFF---------------GDYFKPESDQKIYDEITDLKQLTVV 2388
Query: 2614 GLIHYGRDNQNLD-----ILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLV 2668
+ HY + N+ +++F +E++SRI RVL G LLL G G GR++ L
Sbjct: 2389 -MEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLS 2447
Query: 2669 SHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINS 2728
+ M+ L+ +I++ Y ++ DLK ++ G+ + V L D Q +F+E IN
Sbjct: 2448 TFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINM 2507
Query: 2729 LLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPV-----FNYFTYRIQQNLHIVLIMD 2783
LL++G+VP ++ +E ++ ++ A G V +N+F R+ + L M
Sbjct: 2508 LLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMS 2567
Query: 2784 SANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKK 2843
F P+L C + W + W +++ + + + +D R E
Sbjct: 2568 PIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDV----ELDDNIRVEVVS 2623
Query: 2844 KNSVDPDFLKSFLL-IHESCKAYG-ATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGV 2901
+ +K L + + + TP+ Y+ + + + +SK++E+ ++ G+
Sbjct: 2624 MCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGL 2683
Query: 2902 SKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIA 2961
KL+ A + V + R+ L +E + I ++A +K ++ +
Sbjct: 2684 QKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEAN 2743
Query: 2962 EEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVL 3021
+ KN+ + +L E P + A A+ + P +S ++S++ PP ++ ++E +
Sbjct: 2744 VAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESIC 2803
Query: 3022 RLMGI--------------FDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELL 3067
+ G+ + W K L E + T+D NI + + E
Sbjct: 2804 IMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRER- 2862
Query: 3068 FKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRK 3127
F N F P K S+A L WV+A Y V + + P E L +
Sbjct: 2863 FINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKL 2922
Query: 3128 RKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWN 3187
+ L V ++ L + F+ ++ LE + + + AE LI+ L E RW
Sbjct: 2923 NQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWT 2982
Query: 3188 AQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSA------GLEKFDLR 3241
++ L L++ + YL A R C +W G F L
Sbjct: 2983 EAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLS 3042
Query: 3242 RFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTH 3301
L + W+ GLP D SI+N +++ S SR +IDP QA +W+K
Sbjct: 3043 HTLGDPIKIRAWQIAGLPVDSFSIDNGIIV-------SNSRRWALMIDPHGQANKWIKNM 3095
Query: 3302 LKDSRLEVINQQDSNFITALELAVRFGKTLIIQ----EMDG-VEPVLYPLLRRDLVAQGP 3356
K ++L VI DSN++ LE A++ G ++I+ E+D +EP+L L+ QG
Sbjct: 3096 EKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPIL---LKATFKQQGV 3152
Query: 3357 RYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQ 3416
Y+ ++G+ II+Y+ +F+L+++TR NP P+ A V +NF T GL+ QLL +
Sbjct: 3153 EYM-RLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAA 3211
Query: 3417 HEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSA 3476
EKP+LEE+K +L+ + K L ++E+ +LE L+ S+GNILE++ I+ L+ +K S
Sbjct: 3212 KEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSE 3271
Query: 3477 LIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQR 3536
I E K + + +D+ R Y P+A ++ ++F ISDL+ I MY++SL F+ L+
Sbjct: 3272 EISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMH 3331
Query: 3537 ALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGM---HPELFQE 3593
+L + SE RI+ +I +Y +CR LF+ D+L+F+L G+ E+ +E
Sbjct: 3332 SLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEE 3391
Query: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTL--CFED 3651
+ TG + D + P W+ E++WA ALP L+ + ++
Sbjct: 3392 VWYFLLTGGIALD--------NPYPNPAPQWL-SEKAWAEIVRASALPKLHGLMEHLEQN 3442
Query: 3652 AALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVS 3711
W+ Y+++ +E K +++++++ LRPD++ A+ F + +G +
Sbjct: 3443 LGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIE 3502
Query: 3712 PLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQ-VAMGQGQADLA 3770
+L+ Y ++ P++ ++SP ADP L + A+ G Q +++GQGQ +A
Sbjct: 3503 APTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIA 3562
Query: 3771 IQMLKECARNGDWLCLKNLHLVVSWLPVLEKEL-NTLQPKDT---FRLWLTAEVHPNFTP 3826
+M+ ++G W+ L+N HL SW+P LEK + P+ T FRLWLT+ F
Sbjct: 3563 AKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPV 3622
Query: 3827 ILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRA----HALFSLAWFHAACQ 3882
+LQ+ +K+T E P GL+ NL+R+Y + + +A LF L +FHA Q
Sbjct: 3623 SILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQ 3682
Query: 3883 ERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYF 3942
ERRN+ P GW YEF+ SDLR I + K+V ++ + L YGGR+ +
Sbjct: 3683 ERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDK 3742
Query: 3943 DLRVLQSYLKQFFNSSVIDVFNQRNKKSIFP-YSVSLPQSCSILDYRAVIEKIPEDDKPS 4001
D R+L S L F+ + + + S+ P + +P S Y + +P P
Sbjct: 3743 DRRLLLSLLSMFYCKEI-----EEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPE 3797
Query: 4002 FFGLPANIARSSQRMISSQVI-SQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQN 4060
FGL N + ++Q+ L L R K +E+ +L+ KL ++
Sbjct: 3798 VFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVVEELAQDILS---KLPRD 3854
Query: 4061 SNL--IHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEV 4118
+L + + P + + +L ++ +FN RL + V +SL L + I+G L+SSE+
Sbjct: 3855 FDLEEVMKLYPVVYEESMNTVLRQELI-RFN--RLTKVVRRSLINLGRAIKGQVLMSSEL 3911
Query: 4119 QKLASALLNQKCPLAWQSKWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDL 4177
+++ +++L K P W +K PL Y+ L+AR Q W+DK +
Sbjct: 3912 EEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFW-----I 3966
Query: 4178 SELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQ------IKISGLLLEG 4231
S + +FL + Q AR +D + F ++ QE ++ I GL LEG
Sbjct: 3967 SGFYFTQSFLTGVSQNYARKYTIPIDHIGF--EFEVTPQETVMENNPEDGAYIKGLFLEG 4024
Query: 4232 CSFDGNQLSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVY-TSAERDRV--- 4287
+D + + + LP W+ + + PVY TSA R +
Sbjct: 4025 ARWDRKTMQIGESLPKILYDPLPII--WLKPGESAMFLHQDIYVCPVYKTSARRGTLSTT 4082
Query: 4288 ------VTNIDVPCGGNQDQWIQCGAA 4308
V +I++P Q WI G A
Sbjct: 4083 GHSTNYVLSIELPTDMPQKHWINRGVA 4109
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 1186 bits (3068), Expect = 0.0
Identities = 951/3531 (26%), Positives = 1657/3531 (46%), Gaps = 258/3531 (7%)
Query: 908 LNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLT--IMPQSVEE 965
L +C P K + I++ + L + L +++ F+ A LT + +
Sbjct: 1071 LQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDG 1130
Query: 966 IGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESH 1025
+ + K++ER+ +F+ + LL+T E I + + +
Sbjct: 1131 LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKL 1190
Query: 1026 QLMIKDQIEVMKGNVKSRLQIYYQELE----KFKARWDQLKPGDDVIETGQHNTLDKSAK 1081
+ +K + ++ N S L+ Q+ E +F+ R+ + P + + +L+K K
Sbjct: 1191 AIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFS-FSDPNPYKSLNKQQK 1249
Query: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141
I +E + L F + P++ + +++ ++W
Sbjct: 1250 SISA-------MEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSI 1302
Query: 1142 QEMANEDWITFRTKTYLFEEFLMN---WHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILK 1198
EDW T + K E+ ++ + +R +++ + K VI L+
Sbjct: 1303 -----EDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLR 1357
Query: 1199 YV---RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQ 1255
V + + HW L + + S E L DLL++ + + +++++ +A
Sbjct: 1358 AVSELQNPAIRERHWQQLMQATQVKFKMSEETTL-ADLLQL--NLHSYEDEVRNIVDKAV 1414
Query: 1256 GEVTIREALRELDLWGVGAVFTLIDYE-DSQSRT-MKLIKDWKDIVNQVGDNRCLLQSLK 1313
E + + L+ LD + +++++++ + RT ++K + +V + DN+ LQ+L
Sbjct: 1415 KESGMEKVLKALD-----STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLM 1469
Query: 1314 DSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRF 1368
S Y F +V+ W++KL+ D + +QR W +LE IF R LP + RF
Sbjct: 1470 MSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRF 1529
Query: 1369 NRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPR 1428
+ ++++F+++M D K V T+ G+ N L + L C+K+L E+LE KR AFPR
Sbjct: 1530 DDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPR 1589
Query: 1429 FYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF-----DEKSKHITAMKSLEGEV 1483
FYF+ DLL+IL +P + HL KLF + + F D+ K M S E E
Sbjct: 1590 FYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEY 1649
Query: 1484 VPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAE 1543
+ F + LS VE WLN + M TL + E V T +P+Q+
Sbjct: 1650 MVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCT 1709
Query: 1544 QIKFTEDV-----------ENAIKDHSLHQIE--TQLVNKLEQYTNIDTSSEDPGNTESG 1590
QI +T +V ENAI+D++ QI L+ L GN +G
Sbjct: 1710 QIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLM------------GNLNAG 1757
Query: 1591 ILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF-YMKSDHTCCVQMVDSEF 1649
+K+ + +H DVV ++ +V +++ + W+ QLR + + C + D++
Sbjct: 1758 D-RMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQI 1816
Query: 1650 QYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQ 1709
QY+YEY GN +LV TPLTD+CY+TLTQ++ + +GG P GPAGTGKTE+ K LG LG
Sbjct: 1817 QYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTM 1876
Query: 1710 VLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHR 1769
V VFNC E +D KS G I+ GL + GAWGCFDEFNR+ VLS +++Q++ +QDA++ +
Sbjct: 1877 VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKK 1936
Query: 1770 TVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVI 1829
LG+ + + GIFITMNP GY GR +LP+NLK LFRP AM PD ELI E++
Sbjct: 1937 KAFNFLGEIIGLIPTVGIFITMNP---GYAGRAELPENLKALFRPCAMVVPDFELICEIM 1993
Query: 1830 LYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTT 1889
L +EGF +A++L+RK + ++ L +ELL+ Q HYDWGLRA+K+VL +G+L K G
Sbjct: 1994 LMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL-----KRGDP 2048
Query: 1890 QNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEE 1949
A E ++++ALR + K D F LI D+FP +++ +KQ E
Sbjct: 2049 SRA-EDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVE 2107
Query: 1950 ANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMN 2009
+ + + K ++L E L R V IVG +G+GKS + + L + ++
Sbjct: 2108 LKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLD 2167
Query: 2010 PKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSV 2069
PKA+ +L G I+ TREW DG+ + R + D WII DGDIDP WIESLN+V
Sbjct: 2168 PKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTV 2227
Query: 2070 LDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSW 2129
+DDN++LT+ S ERI + VFE L A+PAT+SR G+++++ + N ++ SW
Sbjct: 2228 MDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSW 2287
Query: 2130 L-RNQPAEYRNNLENWIGDYFEKA---LQWVLKQNDYVVETSLVGTVMNGLSHL------ 2179
+ R + + NL Y L++ K+ V E +++ T++ L L
Sbjct: 2288 IERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTV 2347
Query: 2180 --HGCRDHDE--FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTY 2230
R+ E F+ GG + +++ E W P D Y
Sbjct: 2348 PPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYY 2407
Query: 2231 YDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILV 2290
D + + K P D L ++ T + R + YF L + P +LV
Sbjct: 2408 IDPDTKKFLPWTDKVPSFELDPDVP--LQASLVHTTETIR-IRYFMD-LLMEKSWPVMLV 2463
Query: 2291 GPEGCGKGMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRP 2348
G G GK +L+ L + + V + TTS L L + + +GR Y P
Sbjct: 2464 GNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKP---LEKKSGRNYGP 2520
Query: 2349 KDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN-LEWVGLENIQIVASMS 2407
++LV ++ D+N+P++DK+GT ++Q + ++ +YD + L + N Q VA M+
Sbjct: 2521 PGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMN 2580
Query: 2408 AGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIY 2467
G + +R + ++ +P +E L TIY L L + +I SS+
Sbjct: 2581 PTS--GSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQ-- 2636
Query: 2468 LLAGSMVQVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEI 2526
L + + +++++ A F HY F L+ GL E PLD V +
Sbjct: 2637 -LVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAE--VLKTPLDLV-RL 2692
Query: 2527 VAYEARRLFRDKIVGAKE---LHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSG 2583
+E R++ DK+V K+ LH + T F D G ++L + F H +
Sbjct: 2693 WLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFC------HFAQ 2746
Query: 2584 ARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRV 2643
P PL KL L DV+ Y N ++++LF + + ++ RI+R+
Sbjct: 2747 GIGDPKYVPVTDMAPLNKL----LVDVLDS----YNEVNAVMNLVLFEDAVAHICRINRI 2798
Query: 2644 LSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGI 2703
L P G+ LL G G G+++++ L +++ G +F + +GY + K DL A +
Sbjct: 2799 LESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAV 2858
Query: 2704 EAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG- 2762
+ V L+ D Q FL +IN LL+SGE+PGL+ +E+E ++ ++ Q G
Sbjct: 2859 KNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDT 2918
Query: 2763 --PVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIP 2820
+ +F ++++ L ++L S + PA+ + W W ++ +
Sbjct: 2919 RETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVS 2978
Query: 2821 EMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFL--LIHESCKAYGATPSRY-----M 2873
ET G K S+ F S++ ++E + Y AT RY
Sbjct: 2979 ARFLEETEGIPVI----------KASI--SFFMSYVHTTVNEMSRVYLATERRYNYTTPK 3026
Query: 2874 TFLH---VYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQD 2930
TFL +Y + + K+ EL+ + L+ G+ KL + VD+L K Q LK K +
Sbjct: 3027 TFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNE 3086
Query: 2931 EADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKL 2990
AD +Q++ + + S++K ++ + ++ + E++ + +L + +P + A+
Sbjct: 3087 SADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQE 3146
Query: 2991 AVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAKRGV-R 3044
A+ + +L+E++S PPD + ++ V+ L D SW + K + K
Sbjct: 3147 ALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFL 3206
Query: 3045 EDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLE 3104
+ + FD +I + ++ + ++ +FDP+ + STAAA L +W +++ V
Sbjct: 3207 DSLKKFDKEHIPEACLKAFKP--YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYC 3264
Query: 3105 RIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSK 3164
+ P + L + +++ +++ + + +S L F+ T+E K + E
Sbjct: 3265 DVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADA 3324
Query: 3165 AQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKT 3224
I A L+ L E+ RW V + TL L +AF++Y+ + R
Sbjct: 3325 TNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNE 3384
Query: 3225 CLEE-WTK-----------SAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVIL 3272
+E+ W + GL+ L L +++ W ++GLPSD +S ENA +
Sbjct: 3385 LMEKFWIPYIHNLKVPIPITNGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATI-- 3439
Query: 3273 QIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLI 3332
+ + W P ++D Q +W+K + S L+ I +++ +E A+ G TL+
Sbjct: 3440 -LGNTERW----PLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLL 3493
Query: 3333 IQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAA 3391
I+ + + V+PVL PLL R+ + +G ++IGDK ++Y+ +FRL L T+ NP P+
Sbjct: 3494 IENIGETVDPVLDPLLGRNTIKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQ 3551
Query: 3392 SIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETL 3451
+ T +NF TR GL QLLA + E+PDLE+ K L + + + KI L +LE+SLL L
Sbjct: 3552 AQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARL 3611
Query: 3452 ATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYF 3511
+ + GN L + L+E+L TK +++ I+E + E+ ++ +++ R+ Y P AE AS +YF
Sbjct: 3612 SAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYF 3671
Query: 3512 IISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLF 3571
I++DL+KIN +Y+FSL AF +F++A+Q + +QR+ +L + + VY Y R LF
Sbjct: 3672 ILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLF 3731
Query: 3572 KADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSW 3631
+ D+L+F FQ V D L + + + P Q + W
Sbjct: 3732 ERDKLIFLAQVT-------FQVLSMKKELNPVELDFLLRFPFKAGVVS--PVDFLQHQGW 3782
Query: 3632 AVATLKIALPSLYQTLCFE---DAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQA 3687
++ ++ L + A W+ + E+E FP K +L Q++ +V+
Sbjct: 3783 G-GIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRC 3840
Query: 3688 LRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQEL 3747
LRPDR+ A+ F + +G K V + + Y+E+ I I+SPG DP ++++ L
Sbjct: 3841 LRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEAL 3900
Query: 3748 ANA---ERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELN 3804
H V++GQGQ +A L A G W+ L+N+HLV WL L+K+L
Sbjct: 3901 GKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLE 3960
Query: 3805 --TLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTPE 3857
+ + +R++++AE P+ +L++++KIT E P G+ NL + + +T +
Sbjct: 3961 RYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQD 4020
Query: 3858 --QISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFD 3915
++ K+ + LF+L +FHA ERR + QGW + Y F+ DL N++ +
Sbjct: 4021 TLEMCTKEMEFKC-MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE 4079
Query: 3916 GAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYS 3975
V W+ + L +YGG I + +D R+ ++YL ++ + +++ +
Sbjct: 4080 ANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE------GDVLLAPG 4133
Query: 3976 VSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILGR 4030
+P + Y I++ + P +GL N + +S+++ + + +++
Sbjct: 4134 FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLF--RTVLEMQPKET 4191
Query: 4031 SITAGSKFDREIWSNELSPVL-NLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFN 4089
AG+ RE ++ VL ++ +K+ + N+ + + ++ +++F E+ N
Sbjct: 4192 DSGAGTGVSRE---EKVKAVLDDILEKIPETFNMA-EIMAKAAEKTPYVVVAFQECERMN 4247
Query: 4090 AIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSK-WEGPEDPLQYL 4148
L + +SL L+ ++G ++++V+ L++AL P W ++ + +
Sbjct: 4248 I--LTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4305
Query: 4149 RGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFV 4208
L+ R ++ W L T+ L+ F+P +FL A+ Q AR +D +
Sbjct: 4306 ADLLLRIRELEAWT----TDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLS 4361
Query: 4209 ASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLP-CFMGWIPQ 4262
+ +E + + GL +EG +D + ++ +P F+ IP
Sbjct: 4362 VEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPV 4421
Query: 4263 DACGPYSPDECISLPVY-TSAERDRVVTNIDVPCGGNQDQWIQCGAALFLK 4312
D + EC PVY T V ++ +WI AL L+
Sbjct: 4422 DRMETKNIYEC---PVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQ 4469
Score = 38.1 bits (87), Expect = 0.19
Identities = 50/273 (18%), Positives = 118/273 (43%), Gaps = 27/273 (9%)
Query: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486
L++RP I E+ R +++ L D+ D + + + PL KN+ V +
Sbjct: 543 LMERPLILAEVA-PRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 601
Query: 487 VWVRQLELKVDDTIK----IAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542
W +L+ +++ ++K + ++S + +Q ++++ L+ + ++ + W +
Sbjct: 602 KWSLELQERLEVSMKHLKHVEHPVMSGAEA-KLTYQKYDEMMELLRCHREKIYQQWVAGV 660
Query: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLS-ALGFVIPAKIQ 601
++ D+ L+ V++S LV +LREV+ L+ IP +
Sbjct: 661 DQDCH-------FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAE 713
Query: 602 QVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661
+ + + F K L+ + +YN +++++ ++++S L + S ++
Sbjct: 714 SLFSENETFRKFVGNLELIVGWYN----EVMKAVEFLLIKSELEAIDVKLLS-----AET 764
Query: 662 QITWDNPKELEGYIQKLQNAAERLATENRKLRK 694
+ W+ EG Q +Q E L +++K
Sbjct: 765 TLFWNG----EGVFQYIQEVREILHNLQNRMQK 793
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 1186 bits (3067), Expect = 0.0
Identities = 901/3214 (28%), Positives = 1514/3214 (47%), Gaps = 215/3214 (6%)
Query: 1209 HWLDLFRLLGLP----RGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREAL 1264
HW L + +G+ T+L LL L RV D D++ + +A E+ + +
Sbjct: 1414 HWHQLMKAIGVKFLINEATTLADLLALRLHRVED-------DVRRIVDKAVKELGTEKVI 1466
Query: 1265 RELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDK 1324
E+ F+ YE + L+K + + + N+ LQ+L S Y + F ++
Sbjct: 1467 TEISQTWATMKFS---YEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQ 1523
Query: 1325 VSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRFNRVDEDFRSIM 1379
V W+ KL D + +QR W +LE IF R L K+ RF+ VD +F+ +M
Sbjct: 1524 VLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELM 1583
Query: 1380 TDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLE 1439
K V T + L + +L C+K+L E+LE KR AFPRFYF+ DLL+
Sbjct: 1584 FKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLD 1643
Query: 1440 ILGQSTNPSVIQSHLKKLFAGINSVCFDEK----SKHITAMKSLEGEVVPFKNKVPLSNN 1495
IL + P + HL KLF I + F++ + M S E E VPF+ + +
Sbjct: 1644 ILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGH 1703
Query: 1496 VETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDV---- 1551
VETWL L M++T+ + E + + FP+Q+ + QI +T DV
Sbjct: 1704 VETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAF 1763
Query: 1552 -------ENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDII 1604
E A+KD QI ++L + PG+ + K+ + +
Sbjct: 1764 SRLEEGYETALKDFHKKQI-----SQLNTLITLLLGELPPGDRQ------KIMTICTIDV 1812
Query: 1605 HNIDVV-KQLNQIQVHTT-EDWAWKKQLRF-YMKSDHTCCVQMVDSEFQYTYEYQGNASK 1661
H DVV K ++Q QV + + + W QLR + + C V + D++FQY YEY GN+ +
Sbjct: 1813 HARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPR 1872
Query: 1662 LVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDV 1721
LV TPLTD+CY+TLTQ++ + + G P GPAGTGKTE+ K LG LG V VFNC E +D
Sbjct: 1873 LVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDY 1932
Query: 1722 KSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEV 1781
KS+G I+ GLV+ GAWGCFDEFNR+ VLS V++Q++ I DA++N + LG+ + +
Sbjct: 1933 KSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITL 1992
Query: 1782 NSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVL 1841
+ GIFITMNP GY GR +LP+NLK LFRP AM PD ELI E++L +EGF DA+ L
Sbjct: 1993 KPSVGIFITMNP---GYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARAL 2049
Query: 1842 SRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQA 1901
+RK + ++ L +ELL+ Q HYDWGLRA+K+VL +G+L R +N E ++++A
Sbjct: 2050 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKR------GDKNRPEDQVLMRA 2103
Query: 1902 LRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKK 1961
LR M K D F L+ D+FP +++ ++Q E + + I K
Sbjct: 2104 LRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILK 2163
Query: 1962 ALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGH 2021
++L E L R V +VG +G GKS + R L + +NPKA+ +L G
Sbjct: 2164 VVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGF 2223
Query: 2022 IDMDTREWSDGVLTNS---------ARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDD 2072
I TREW DG + S R+ D WI+ DGDIDP WIESLN+V+DD
Sbjct: 2224 IHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDD 2283
Query: 2073 NRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL-R 2131
N++LT+ S ERI P + +FE H L A+PAT+SR G+++++ ++ N + SW+ R
Sbjct: 2284 NKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDR 2343
Query: 2132 NQPAEYRNNLENWIGDYFEKALQWV---LKQNDYVVETSLVGTVMNGLSHLHGCRDHDE- 2187
+ + NL Y L + K + E+SLV T+ L L +
Sbjct: 2344 RRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSD 2403
Query: 2188 ---------FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTYYDS 2233
F+ I GG L ++ + W ++ P D Y D
Sbjct: 2404 SPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDH 2463
Query: 2234 TRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPE 2293
+L + K + D L ++ T + R L YF L K P +LVG
Sbjct: 2464 KTKKLLPWADKIAQFTMDPDVP--LQTVLVHTTETAR-LRYFMELLLEKGK-PLMLVGNA 2519
Query: 2294 GCGKGMLLRYAFSQLRSTQIAT-VHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCE 2352
G GK + + + L I + V + TTS L + L + + G Y P +
Sbjct: 2520 GVGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEKP---LEKKAGHNYGPGGNK 2576
Query: 2353 RLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD-ENLEWVGLENIQIVASMSAGGR 2411
+L+ ++ D+N+P++D +GT ++Q + Y +YD + + + N Q VA M+
Sbjct: 2577 KLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNP--M 2634
Query: 2412 LGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAG 2471
+G + R + + ++P + L TIYG + SI S L
Sbjct: 2635 VGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGP---TLIQ 2691
Query: 2472 SMVQVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYE 2530
+ + ++ + F HY F L+ G+ E PLD ++ + +E
Sbjct: 2692 ATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPE--CLKGPLD-LIHLWLHE 2748
Query: 2531 ARRLFRDKIVGAKELHLFD-IILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPG 2589
+ R++ DK++ K+ LF +L + ++ G D + A
Sbjct: 2749 SARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGK------- 2801
Query: 2590 QPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGG 2649
PH P+ LK ++ + L +Y N + ++LF + ++++ RI R+L P G
Sbjct: 2802 ---DPHYMPVKDWEV--LKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQG 2856
Query: 2650 SLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVV 2709
LL G G G+++++ L +++ G +F ++ GY +++ + DL ++ G + V
Sbjct: 2857 CALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTV 2916
Query: 2710 LLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGP---VFN 2766
LL D Q + +FL +IN LL+SGE+P L++ E+++ ++ + ++ G +
Sbjct: 2917 FLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWK 2976
Query: 2767 YFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSE 2826
+F R++ L I+L + PA+ + W W ++ + E
Sbjct: 2977 FFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEE 3036
Query: 2827 TGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAY--------GATPSRYMTFLHV 2878
T G E + K+S+ ++E Y TP ++ + +
Sbjct: 3037 TKGIEPVH---------KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISL 3087
Query: 2879 YSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQM 2938
+ + K+ E+ +++ L G+ KL + V +L + Q L+ + +A+A +
Sbjct: 3088 FKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITK 3147
Query: 2939 ITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPE 2998
I + + S +KT + + ++ ++ +++ + + +L + +P + A A+ +
Sbjct: 3148 IGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRV 3207
Query: 2999 SLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAK-RGVREDIATFDA 3052
+LSE+++ PP + ++ V+ L+ D SW + K F+ K + + +D
Sbjct: 3208 NLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDK 3267
Query: 3053 RNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETE 3112
+I + + V E K+ F+P + S AAA L AWV I++ V + P
Sbjct: 3268 EHIPENCLKVVNEHYLKDP-EFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQA 3326
Query: 3113 QAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAA 3172
A L ++ + + L + + +S L F+ T+E + + EV++ +TIK A
Sbjct: 3327 LAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLA 3386
Query: 3173 EVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTC------- 3225
L+ +L+ + RW + + TL L AAF++Y+ R+
Sbjct: 3387 NRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVP 3446
Query: 3226 -LEEWTKSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVC 3284
L++ E DL L ++ W +EGLPSD +S ENA ++ + W
Sbjct: 3447 FLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTH---CERW---- 3499
Query: 3285 PFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DGVEPVL 3343
P +IDP Q +W+K L+V + F+ A+E A+ FG ++I+ + + ++PVL
Sbjct: 3500 PLVIDPQQQGIKWIKNKY-GMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVL 3558
Query: 3344 YPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTR 3403
PLL R+ + +G ++IGDK ++N+ FRL L T+ NP P+ + T +NFT T
Sbjct: 3559 DPLLGRNTIKKGK--YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTE 3616
Query: 3404 SGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKD 3463
GL QLLA + E+PDLE+ K L + + D KI+L LE+ LL L+ ++G+ L++
Sbjct: 3617 DGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTK 3676
Query: 3464 LIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMY 3523
L+E L TK + A I+ + E+ + + +++ R+ Y P+A AS +YF+I+DL KIN +Y
Sbjct: 3677 LVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLY 3736
Query: 3524 RFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFV 3583
+FSL AF LF RA++ E+ + RI L+ S+ H V+ Y + LF+ D+L F
Sbjct: 3737 QFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMA 3796
Query: 3584 RGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSL 3643
+ L ++ E D + + +LR + P +SW+ A IA+
Sbjct: 3797 FQI---LLRKKEIDP---LELDFLLRFTVEHTHLS---PVDFLTSQSWS-AIKAIAVMEE 3846
Query: 3644 YQTLCFE---DAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALF 3700
++ + + A WR + + E+E KK SL Q++++++A+RPDR+ A+ F
Sbjct: 3847 FRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNF 3906
Query: 3701 ACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQ----ELANAERSGEC 3756
+ LG K V L+L + ++E+ PI I+SPG D ++L+ L SG+
Sbjct: 3907 VEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGK- 3965
Query: 3757 YHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKD--TFRL 3814
+H V++GQGQ +A L++ ++ G W+ L+N+HLV WL LEK L +R+
Sbjct: 3966 FHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRV 4025
Query: 3815 WLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTPE--QISKKDNTHR 3867
+++AE P LL++S+KIT E P G+ NL ++ + +I K+ +
Sbjct: 4026 FMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEFK 4085
Query: 3868 AHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHG 3927
+ LFSL +FHA R + PQGW++ Y F+ DL +++ + V WE +
Sbjct: 4086 S-ILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRY 4144
Query: 3928 LLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDY 3987
L +YGG I + +D ++ + YL++F N S+ + + + + P Y
Sbjct: 4145 LFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTE------DELMLAPGFAAPPYLDYAGY 4198
Query: 3988 RAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVI-SQLRILGRSITAGSKFDREIWSNE 4046
IE++ + P+ +GL N + S+ + + L + R+ +G + +
Sbjct: 4199 HQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKV 4258
Query: 4047 LSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSK 4106
+ + ++ +KL + N+ + + ++R ++ F E+ N L++ + SL L
Sbjct: 4259 KNVLDDILEKLPEEFNMA-EIMQKNSNRSPYVLVCFQECERMNI--LIREIRISLEQLDL 4315
Query: 4107 VIRGTTLLSSEVQKLASALLNQKCPLAWQS-KWEGPEDPLQYLRGLVARALAIQNWVDKA 4165
++G LS V+ AL P W + Q+ L+ R + W
Sbjct: 4316 SLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWT--- 4372
Query: 4166 EKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQE-----AKL 4220
+ L + LS F+P +FL A+ Q AR +D + A + +E +
Sbjct: 4373 -QDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPRE 4431
Query: 4221 QIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLP-CFMGWIPQDACGPYSPDECISLPVY 4279
+ GL +EG +D + + ++ +P F P D EC PVY
Sbjct: 4432 GAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYEC---PVY 4488
Query: 4280 -TSAERDRVVTNIDVPCGGNQDQWIQCGAALFLK 4312
T + + +W+ G AL L+
Sbjct: 4489 RTKLRGPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
Score = 42.7 bits (99), Expect = 0.008
Identities = 44/229 (19%), Positives = 98/229 (42%), Gaps = 33/229 (14%)
Query: 477 KNLSEVVNSIVWVRQLELKVD---DTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQE 533
KN+ ++ W +Q+ ++ L P +Q ++ L +E
Sbjct: 626 KNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESR 685
Query: 534 QFDDWSRDIQSGLSDSRSGLC-IEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSAL 592
+++W ++ +C + +++ + +GLL V++ +LV +LREV+ L L
Sbjct: 686 IYNEWKSNVDE--------ICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLML 737
Query: 593 GFVIPAKIQQVANIAQK-FCKQAIILKQVAHF------YNSIDQQMIQSQRPMMLQSALA 645
K Q + + A F K+ ILK + + YN + Q +++ + P++ A
Sbjct: 738 ------KKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRA 791
Query: 646 FEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRK 694
++ + + + +TW + + GYI++++ A L + +K
Sbjct: 792 IDEQL------TAATTWLTWQD--DCWGYIERVRAATSELEHRVERTQK 832
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 1184 bits (3063), Expect = 0.0
Identities = 933/3614 (25%), Positives = 1661/3614 (45%), Gaps = 214/3614 (5%)
Query: 811 NQFKGVGEAGD----ESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQV 866
N +K V E + S+ S +I+ +T + D F+R + + + KE + +
Sbjct: 1105 NYYKNVSENKEIVKLVSVLSTIINSTKKEVIT----SMDCFKRYNHIWQKGKEEAIKTFI 1160
Query: 867 DMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKL 926
L+ ++E + +E+ P V V + + +K + +
Sbjct: 1161 TQSPLLS-------EFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAW 1213
Query: 927 FDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKPEIL-- 984
++ K ++ + I + E + L + ++++ D + + L+E + E +
Sbjct: 1214 MVVIGRHCNKKYRSEMENIFMLIEEFNKKLN---RPIKDLDDIRIAMAALKEIREEQISI 1270
Query: 985 -----PLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGN 1039
P+ + NR +A ++ + L W+K Q + K
Sbjct: 1271 DFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKE 1330
Query: 1040 VKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKK 1099
+ S ++++ Q+ +F +D P ++ + S +LI + +FD++
Sbjct: 1331 LISAVEVFLQDCHQFYLDYDLNGPMASGLKPQE-----ASDRLIMFQN-QFDNIYRKYIT 1384
Query: 1100 LVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLF 1159
F L + I K + +I+ Y + + W +
Sbjct: 1385 YTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINN 1444
Query: 1160 EEFLMNWHDRLRKVE---EHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRL 1216
E L+ + +R RK+ + + L+ +D + P+L+Y+ + + HW + L
Sbjct: 1445 E--LLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTL 1502
Query: 1217 LGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVF 1276
G E +++ ++ +++D+ A E I + L+++ F
Sbjct: 1503 TGHSLDVGNESFKLRNIMEAP--LLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTF 1560
Query: 1277 TLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELD 1336
T ++ ++ + +I+ + D+ LL SL + Y F+ ++ W + L+
Sbjct: 1561 TFGSFK-TRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNST 1619
Query: 1337 EYLQNLNHIQRKWVYLEPIFGRG----ALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLT 1392
+ +++ +Q W+YLE +F G LPKE RF+ +D+ + IMT + V
Sbjct: 1620 DIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCC 1679
Query: 1393 THAGIRNSLLT-ILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQ 1451
LL +LDQL+ CQKSL +LE+KR FPRF+F+ D LLEILGQ+++ IQ
Sbjct: 1680 VGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQ 1739
Query: 1452 SHLKKLFAGINSVCFDEKS-KHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKT 1510
+HL +F I SV F EK I ++ S EGE + V NVE WLN L E + +
Sbjct: 1740 AHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSS 1799
Query: 1511 LEQLLKECVTTGRSSQGAVDPSL--FPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLV 1568
L ++++ + + + L FP+Q+ L Q+ +T D E A+++ + Q
Sbjct: 1800 LHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKT 1859
Query: 1569 NK--LEQY-TNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWA 1625
N+ LE T ID ++ D +TE +K + LI +H D+ L + + + D+
Sbjct: 1860 NQAFLELLNTLIDVTTRDLSSTE----RVKYETLITIHVHQRDIFDDLCHMHIKSPMDFE 1915
Query: 1626 WKKQLRFYMKSDHT-CCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLG 1684
W KQ RFY D + + D F Y E+ G +LV TPLTD+CY+TL QA+ M +G
Sbjct: 1916 WLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMG 1975
Query: 1685 GNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFN 1744
G P GPAGTGKTE+ K +G LG+ V+VFNC + +D + +GRIF GL + G+WGCFDEFN
Sbjct: 1976 GAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFN 2035
Query: 1745 RLEESVLSAVSMQIQTIQDALKNHRTVCELL-GKEVEVNSNSGIFITMNPAGKGYGGRQK 1803
R++ VLS + QI I K H+ G V +N G+F+TMNP GY GRQ+
Sbjct: 2036 RIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNP---GYAGRQE 2092
Query: 1804 LPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYD 1863
LP+NLK FR VAM PD ++I V L S GF D VL+RK ++ L E L+ Q HYD
Sbjct: 2093 LPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYD 2152
Query: 1864 WGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIK 1923
+GLR + +VLR G ++ N T ES IV++ LR +SK D F +LI+
Sbjct: 2153 FGLRNILSVLRTLG-AAKRANPMDT-----ESTIVMRVLRDMNLSKLIDEDEPLFLSLIE 2206
Query: 1924 DVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGA 1983
D+FP I L + Y EL AA+ + EEA P K ++L+E R G++ +GPSGA
Sbjct: 2207 DLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGA 2266
Query: 1984 GKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVR 2043
GK+T L A+ GK ++ MNPKA+ Q+ G +D+ T +W+DG+ + R+ +R
Sbjct: 2267 GKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLR 2326
Query: 2044 EPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCAS 2103
+ WII DG +D WIE+LNSVLDDN+ LT+ +G+RI PN +FE H++ AS
Sbjct: 2327 AKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNAS 2386
Query: 2104 PATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQNDYV 2163
PAT+SR GM+F+S D + +++ +L+ + + L + F ++ ++ +Y
Sbjct: 2387 PATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYK 2446
Query: 2164 VETSLVGTVMNGLSHLHGCRDHDE-------------FIINLIRGLGGNLNMKSRLEFTK 2210
+E + ++ L G E F+ L+ G L + R +
Sbjct: 2447 MEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGR----R 2502
Query: 2211 EVFHWARESP------PDFHKPMDT---YYDSTRGRLATYVLKKPEDLTADDFSNGLTLP 2261
+ W R P P P DT YY + G + + E L D +
Sbjct: 2503 RLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSI 2562
Query: 2262 VIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQL--RSTQIATVHCS 2319
++ D R D+ ++ K +L+G +G K ++++ S+ I +++ S
Sbjct: 2563 LVPNVDNVR-TDFLIQTIAKQGK-AVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFS 2620
Query: 2320 AQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQ 2379
+ TT + + + G Y P +++ +++ D+N+P +++WG ++
Sbjct: 2621 SATTPLMFQRTIES---YVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVR 2677
Query: 2380 QVLTYQGFY--DENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQ 2437
Q++ GFY ++ E+ + +IQ +A+M G GR+ + R + + P
Sbjct: 2678 QLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGG-GRNDIPQRLKRQFSIFNCTLPSEAS 2736
Query: 2438 LQTIYGAY-LEPVLHKNLKNHSIWGSSSKIYLLAGSMVQVYE----QVRAKFTVDDYSHY 2492
+ I+G + + + + S +K+ L + Q+ + AKF HY
Sbjct: 2737 VDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKF------HY 2790
Query: 2493 FFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIIL 2552
F L++ G+ E P D +L++ +E +R+ D+ + ++ FD L
Sbjct: 2791 VFNLRDLSRVWQGMLNTTSE--VIKEPND-LLKLWKHECKRVIADRFTVSSDVTWFDKAL 2847
Query: 2553 TSVFQGDWGSD---ILDNMSDSFYVTW--GARHNSGARAAPGQ-PLPPHGKPLGKLNSTD 2606
S+ + ++G + ++D D+++V + A +G + P +P+ +
Sbjct: 2848 VSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESF--SH 2905
Query: 2607 LKDVIKKGLIHYGRD--NQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTI 2664
LK+ + L Y +D++ F + + ++ +I RV+ P G+ LL G G G++++
Sbjct: 2906 LKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSL 2965
Query: 2665 TSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLE 2724
T L S + G V F ++R Y DLK + + AG + + + + D + +FLE
Sbjct: 2966 TRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLE 3025
Query: 2725 MINSLLSSGEVPGLYTLEELEPLLLPLKDQASQD-----GFFGPVFNYFTYRIQQNLHIV 2779
+N++LSSGEV L+ +E++ + L ++ + +YF R++QNLHIV
Sbjct: 3026 YMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIV 3085
Query: 2780 LIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRK 2839
L F PAL C + W W ++ + E + KK
Sbjct: 3086 LCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEV 3145
Query: 2840 EEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQA 2899
+ + D K ++ TP Y++F+ Y I K E+ + +
Sbjct: 3146 VQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNT 3205
Query: 2900 GVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHR 2959
G+ KL EA V L+++ + L+ D+AD L+ +T+ Q A + K E++++K R
Sbjct: 3206 GLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDR 3265
Query: 2960 IAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEG 3019
V I + K +++L+ +P + EA+ A+ I+P ++ +R+L PP +I I++
Sbjct: 3266 AQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDC 3325
Query: 3020 VLRLM-------------GIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEEL 3066
VL L SW + +++ F I++E+ E +
Sbjct: 3326 VLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSP- 3384
Query: 3067 LFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDR 3126
+ ++ + AKR A L +W KA + + + + PL+ E+
Sbjct: 3385 -YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQD 3443
Query: 3127 KRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRW 3186
+K + L+ ++ ++ +++ +E L + + + ++ A LI+ L E +RW
Sbjct: 3444 LQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERW 3503
Query: 3187 NAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDLRRFLCT 3246
Q E + L LA AF++Y + R L +W K K + L
Sbjct: 3504 TEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNL-N 3562
Query: 3247 ESEQLI-------WKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLK 3299
SE LI W +GLP+DDLSI+N +++ + SR P LIDP +Q W+K
Sbjct: 3563 LSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKA------SRY-PLLIDPQTQGKIWIK 3615
Query: 3300 THLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRY 3358
+ L++ + F LE ++ G+ L+I+++ + ++P L +L R+ + G +
Sbjct: 3616 NKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTF 3675
Query: 3359 VVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHE 3418
V++GDK +D + FRL+++T+ PNP P+ ++ + ++FT T GL QLL I E
Sbjct: 3676 KVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTE 3735
Query: 3419 KPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALI 3478
K +LE+++T L++ K ++ +LE++LL L ++QG+++E++ LI L+ TK ++ +
Sbjct: 3736 KQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEV 3795
Query: 3479 QESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRAL 3538
+ L+ S + ++ ++ R+ Y P+A S +YF+I+++ +N MY+ SL FL LF +L
Sbjct: 3796 TQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSL 3855
Query: 3539 QNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDT 3598
S T +RI ++I + + VY+Y R L++ + +F L + + + +
Sbjct: 3856 ARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEF 3915
Query: 3599 FTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDA------ 3652
T + G L L + + W + + L L + F D
Sbjct: 3916 LTLIKGGASL-----------DLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISR 3964
Query: 3653 --ALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKE 3709
+W+ +++ E+E P+ K + F+++L++++ PDR + + ++G K
Sbjct: 3965 NEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKY 4024
Query: 3710 VSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADL 3769
+ L+L++ ++E+ P++ ++S G+DP+ + L + Y V+MGQGQ
Sbjct: 4025 AEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRY--VSMGQGQEVH 4082
Query: 3770 AIQMLKECARNGDWLCLKNLHLVVSWL-PVLEKELNTLQPKDTFRLWLTAEVHPNFTPIL 3828
A ++L++ NG W L+N HL + ++ +++ + T D FRLW+T E H F L
Sbjct: 4083 ARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITL 4142
Query: 3829 LQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYI 3888
LQ S+K + P GL+ L RTY + + + + L+++A+ H+ QERR +
Sbjct: 4143 LQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKFG 4202
Query: 3889 PQGWTKFYEFSLSDLRAGYNIIDRLFDG---AKDVQWEFVHGLLENAIYGGRIDNYFDLR 3945
GW YEF+ +D A I D K V W + ++ YGGR+ + +D R
Sbjct: 4203 ALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKR 4262
Query: 3946 VLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGL 4005
+L ++ K +F+ N F ++P+ ++ +Y I+ +P D P FGL
Sbjct: 4263 LLNTFAKVWFSE------NMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGL 4316
Query: 4006 PANIARSSQRMISSQVISQ-LRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLI 4064
N + Q ++ V+ L I + + G RE L+ ++ +KL +
Sbjct: 4317 HPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLAD--DMLEKLPPDYVPF 4374
Query: 4065 HQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASA 4124
K P+ F+ E R++ V +L L I GT ++S ++
Sbjct: 4375 EVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDC 4434
Query: 4125 LLNQKCPLAWQSKWEGPEDPLQY-LRGLVARALAIQNWVDKAEKQALLSETLDLSELFHP 4183
+ + + P AW K L + L+ R +WV ++ F+P
Sbjct: 4435 MFDARIP-AWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFW-----MTGFFNP 4488
Query: 4184 DTFLNALRQETARA-VGRSVDSLKF---VASW-KGRLQEAKLQ-IKISGLLLEGCSFDGN 4237
FL A+RQE RA G ++D++ V W K + + + + GL LEG +D
Sbjct: 4489 QGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKR 4548
Query: 4238 QLSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERD--RVVTNIDVPC 4295
+ + + ++P + + S P+Y R + +D+
Sbjct: 4549 NMKLIESKPKVLFELMPVIRIYAENNT---LRDPRFYSCPIYKKPVRTDLNYIAAVDLRT 4605
Query: 4296 GGNQDQWIQCGAAL 4309
+ W+ G AL
Sbjct: 4606 AQTPEHWVLRGVAL 4619
Score = 45.1 bits (105), Expect = 0.002
Identities = 87/500 (17%), Positives = 206/500 (41%), Gaps = 50/500 (10%)
Query: 191 SKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWRQTEHDHYPESRMLH 250
+K+ Y L E Y+ D LS+++ + + ++ + S +
Sbjct: 341 AKDNVKYLYTL-EKCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVK 399
Query: 251 LLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNHLTGQVWQRYV 310
+ + I + ++ GT ++W P +V+E + + I + +++ + C H T Q ++
Sbjct: 400 VTNQIISACKAYITNN-GTASIWNQPQDVVEEKILSAIKLKQEYQL-CFHKTKQKLKQN- 456
Query: 311 PHPWK---NEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTRVFEPFTG 367
P+ + +E Y + +RL +++ I T + + ++ E + + ++
Sbjct: 457 PNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVA 516
Query: 368 -LNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYI----SEIQDSPQQLLQAFL 422
+ +YN + K Q + + +L+ ++ ++IQ++ Q L L
Sbjct: 517 TIKKKEYNFLDQR--KMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQAL--RML 572
Query: 423 KYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEV 482
K E + P + + ++ L+ ++++ D + + P +N +
Sbjct: 573 KKFERLNIPNLGID---DKYQLI------LENYGADIDMISKLYTKQKYDPPLARNQPPI 623
Query: 483 VNSIVWVRQLELKVDDTIKIAE---ALLSDL---PGFRCFHQSAKDLLDQLKLYEQEQFD 536
I+W RQL ++ +++ + A+LS P R +++ AK LL+ L+ +
Sbjct: 624 AGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRA--- 680
Query: 537 DWSRDIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVI 596
W R I+ + L ++A G L V++ +++IL RE ++ +G +
Sbjct: 681 -WLRQIEEIHVGLEASLLVKA--------PGTGELFVNFDPQILILFRETECMAQMGLEV 731
Query: 597 PAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAG 656
+ ++ + +K + Y Q ++S+ P ++ L + K +A
Sbjct: 732 SPLATSLFQKRDRYKRNFSNMKMMLAEY-----QRVKSKIPAAIEQ-LIVPHLAKVDEAL 785
Query: 657 SGGKSQITWDNPKELEGYIQ 676
G + +TW + +E Y++
Sbjct: 786 QPGLAALTWTS-LNIEAYLE 804
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1160 bits (3001), Expect = 0.0
Identities = 949/3556 (26%), Positives = 1647/3556 (46%), Gaps = 284/3556 (7%)
Query: 908 LNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLT--IMPQSVEE 965
L +C P K + I++ + L + L +++ F+ A LT + +
Sbjct: 1062 LQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDG 1121
Query: 966 IGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESH 1025
+ + K++ER+ +F+ + LL+T E I + + +
Sbjct: 1122 LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKL 1181
Query: 1026 QLMIKDQIEVMKGNVKSRLQIYYQELE----KFKARWDQLKPGDDVIETGQHNTLDKSAK 1081
+ +K + ++ N S L+ Q+ E +F+ R+ + P N K
Sbjct: 1182 AIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAP----FSFSDPNPYKSLNK 1237
Query: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141
+ K I + L F + P++ + +++ ++W
Sbjct: 1238 VFLLKGI--------MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSI 1289
Query: 1142 QEMANEDWITFRTKTYLFEEFLMN---WHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILK 1198
EDW T + K E+ ++ + +R +++ + K VI L+
Sbjct: 1290 -----EDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLR 1344
Query: 1199 YV---RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQ 1255
V + + HW L + + S E L DLL++ + + +++++ +A
Sbjct: 1345 AVSELQNPAIRERHWQQLMQATQVKFKMSEETTL-ADLLQL--NLHSYEDEVRNIVDKAV 1401
Query: 1256 GEVTIREALRELDLWGVGAVFTLIDYE-DSQSRT-MKLIKDWKDIVNQVGDNRCLLQSLK 1313
E + + L+ LD + +++++++ + RT ++K + +V + DN+ LQ+L
Sbjct: 1402 KESGMEKVLKALD-----STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLM 1456
Query: 1314 DSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRF 1368
S Y F +V+ W++KL+ D + +QR W +LE IF R LP + RF
Sbjct: 1457 MSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRF 1516
Query: 1369 NRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPR 1428
+ ++++F+++M D K V T+ G+ N L + L C+K+L E+LE KR AFPR
Sbjct: 1517 DDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPR 1576
Query: 1429 FYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF-----DEKSKHITAMKSLEGEV 1483
FYF+ DLL+IL +P + HL KLF + + F D+ K M S E E
Sbjct: 1577 FYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEY 1636
Query: 1484 VPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAE 1543
+ F + LS VE WLN + M TL + E V T +P+QI E
Sbjct: 1637 MVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQIWWTTE 1696
Query: 1544 Q----IKFTEDVENAIKDHSLHQIE--TQLVNKLEQYTNIDTSSEDPGNTESGILELKLK 1597
+ E ENAIKD++ QI L+ L GN +G +K+
Sbjct: 1697 VGLAFARLEEGYENAIKDYNKKQISQLNVLITLLI------------GNLNAGD-RMKIM 1743
Query: 1598 ALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF-YMKSDHTCCVQMVDSEFQYTYEYQ 1656
+ +H DVV ++ V +++ + W+ QLR + + C + D++ QY+YEY
Sbjct: 1744 TICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800
Query: 1657 GNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCD 1716
GN +LV TPLTD+CY+TLTQ++ + +GG P GPAGTGKTE+ K LG LG V VFNC
Sbjct: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860
Query: 1717 EGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLG 1776
E +D KS G I+ GL + GAWGCFDEFNR+ VLS +++Q++ +QDA++ + LG
Sbjct: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920
Query: 1777 KEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFK 1836
+ + + GIFITMNP GY GR +LP+NLK LFRP AM PD ELI E++L +EGF
Sbjct: 1921 EIIGLIPTVGIFITMNP---GYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFL 1977
Query: 1837 DAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESH 1896
+A++L+RK + ++ L +ELL+ Q HYDWGLRA+K+VL +G+L K G A E
Sbjct: 1978 EARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL-----KRGDPSRA-EDQ 2031
Query: 1897 IVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIP 1956
++++ALR + K D F LI D+FP +++ +KQ E +
Sbjct: 2032 VLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAED 2091
Query: 1957 NQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRY 2016
+ + K ++L E L R V IVG +G+GKS + + L + ++PKA+
Sbjct: 2092 SFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCD 2151
Query: 2017 QLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLL 2076
+L G I+ TREW DG+ + R + D WII DGDIDP WIESLN+V+DDN++L
Sbjct: 2152 ELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVL 2211
Query: 2077 TMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL-RNQPA 2135
T+ S ERI + VFE L A+PAT+SR G+++++ + N ++ SW+ R +
Sbjct: 2212 TLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ 2271
Query: 2136 EYRNNLENWIGDYFEKA---LQWVLKQNDYVVETSLVGTVMNGLSHL--------HGCRD 2184
+ NL Y L++ K+ V E +++ T++ L L R+
Sbjct: 2272 SEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRE 2331
Query: 2185 HDE--FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTYYDSTRGR 2237
E F+ GG + +++ E W P D Y D +
Sbjct: 2332 LYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKK 2391
Query: 2238 LATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGK 2297
+ K P D L ++ T + R + YF L + P +LVG G GK
Sbjct: 2392 FLPWTDKVPSFELDPDVP--LQASLVHTTETIR-IRYFMD-LLMEKSWPVMLVGNAGTGK 2447
Query: 2298 GMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLV 2355
+L+ L + + V + TTS L L + + +GR Y P ++LV
Sbjct: 2448 SVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKP---LEKKSGRNYGPPGTKKLV 2504
Query: 2356 LYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN-LEWVGLENIQIVASMSAGGRLGR 2414
++ D+N+P++DK+GT ++Q + ++ +YD + L + N Q VA M+ G
Sbjct: 2505 YFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GS 2562
Query: 2415 HKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMV 2474
+ +R + ++ +P +E L TIY L L + +I SS+ L + +
Sbjct: 2563 FTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQ---LVAAAL 2619
Query: 2475 QVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARR 2533
+++++ A F HY F L+ GL E PLD V + +E R
Sbjct: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAE--VLKTPLDLV-RLWLHETER 2676
Query: 2534 LFRDKIVGAKE---LHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQ 2590
++ DK+V K+ LH + T F D G ++L + F H + P
Sbjct: 2677 VYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFC------HFAQGIGDPKY 2730
Query: 2591 PLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGS 2650
PL KL L DV+ Y N ++++LF + + ++ RI+R+L P G+
Sbjct: 2731 VPVTDMAPLNKL----LVDVLDS----YNEVNAVMNLVLFEDAVAHICRINRILESPRGN 2782
Query: 2651 LLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVL 2710
LL G G G+++++ L +++ G +F + +GY + K DL A ++ V
Sbjct: 2783 ALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVF 2842
Query: 2711 LLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG---PVFNY 2767
L+ D Q FL +IN LL+SGE+PGL+ +E+E ++ ++ Q G + +
Sbjct: 2843 LMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKF 2902
Query: 2768 FTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSET 2827
F ++++ L ++L S + PA+ + W W ++ + ET
Sbjct: 2903 FIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET 2962
Query: 2828 GGGEKYNDKKRKEEKKKNSVDPDFLKSFL--LIHESCKAYGATPSRY-----MTFLH--- 2877
G + K S+ F S++ ++E + Y AT RY TFL
Sbjct: 2963 EG---------IPWEVKASI--SFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIK 3011
Query: 2878 VYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQ 2937
+Y + + K+ EL+ + L+ G+ KL + VD+L K Q LK K + AD +Q
Sbjct: 3012 LYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQ 3071
Query: 2938 MITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKP 2997
++ + + S++K ++ + ++ + E++ + +L + +P + A+ A+ +
Sbjct: 3072 VVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNK 3131
Query: 2998 ESLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAKRGV-REDIATFD 3051
+L+E++S PPD + ++ V+ L D SW + K + K + + FD
Sbjct: 3132 NNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFD 3191
Query: 3052 ARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLET 3111
+I + ++ + ++ +FDP+ + STAAA L +W +++ V + P
Sbjct: 3192 KEHIPEACLKAFKP--YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ 3249
Query: 3112 EQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKA 3171
+ L + +++ +++ + + +S L F+ T+E K + E I
Sbjct: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILL 3309
Query: 3172 AEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEE-WT 3230
A L+ L E+ RW V + TL L +AF++Y+ + R +E+ W
Sbjct: 3310 ANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWI 3369
Query: 3231 K-----------SAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKS 3279
+ GL+ L L +++ W ++GLPSD +S ENA + + +
Sbjct: 3370 PYIHNLKVPIPITNGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATI---LGNTER 3423
Query: 3280 WSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DG 3338
W P ++D Q +W+K + S L+ I +++ +E A+ G TL+I+ + +
Sbjct: 3424 W----PLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGET 3478
Query: 3339 VEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVN 3398
V+PVL PLL R+ + +G ++IGDK ++Y+ +FRL L T+ NP P+ + T +N
Sbjct: 3479 VDPVLDPLLGRNTIKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLIN 3536
Query: 3399 FTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNI 3458
F TR GL QLLA + E+PDLE+ K L + + + KI L +LE+SLL L+ + GN
Sbjct: 3537 FLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNF 3596
Query: 3459 LENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSK 3518
L + L+E+L TK +++ I+E + E+ ++ +++ R+ Y P AE AS +YFI++DL+K
Sbjct: 3597 LGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNK 3656
Query: 3519 INNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMF 3578
IN +Y+FSL AF +F++A+Q + +QR+ +L + + VY Y R LF+ D+L+F
Sbjct: 3657 INPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIF 3716
Query: 3579 ALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKI 3638
FQ V D L + + + P Q + W +
Sbjct: 3717 LAQVT-------FQVLSMKKELNPVELDFLLRFPFKAGVVS--PVDFLQHQGWG-GIKAL 3766
Query: 3639 ALPSLYQTLCFE---DAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQALRPDRLQ 3694
+ ++ L + A W+ + E+E FP K +L Q++ +V+ LRPDR+
Sbjct: 3767 SEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPDRMT 3825
Query: 3695 SAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANA---E 3751
A+ F + +G K V + + Y+E+ I I+SPG DP ++++ L
Sbjct: 3826 YAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFT 3885
Query: 3752 RSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL--------KNLHLVVSWLPVLEKEL 3803
H V++GQGQ +A L A G W+ L +N+HLV WL L+K+L
Sbjct: 3886 IDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKL 3945
Query: 3804 N--TLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTP 3856
+ + +R++++AE P+ +L++++KIT E P G+ NL + + +T
Sbjct: 3946 ERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQ 4005
Query: 3857 E--QISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLF 3914
+ ++ K+ + LF+L +FHA ERR + QGW + Y F+ DL N++
Sbjct: 4006 DTLEMCTKEMEFKC-MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYL 4064
Query: 3915 DGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPY 3974
+ V W+ + L +YGG I + +D R+ ++YL ++ + +++ +
Sbjct: 4065 EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE------GDVLLAP 4118
Query: 3975 SVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILG 4029
+P + Y I++ + P +GL N + +S+++ + + Q +
Sbjct: 4119 GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETD 4178
Query: 4030 RSITAGSKFDREIWSNELSP-------------------------VLNLWKKLNQNSNLI 4064
G + + S +L P + ++ +K+ + N+
Sbjct: 4179 SGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMA 4238
Query: 4065 HQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASA 4124
+ + ++ +++F E+ N L + +SL L+ ++G ++++V+ L++A
Sbjct: 4239 -EIMAKAAEKTPYVVVAFQECERMNI--LTNEMRRSLKELNLGLKGELTITTDVEDLSTA 4295
Query: 4125 LLNQKCPLAWQSK-WEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHP 4183
L P W ++ + + L+ R ++ W L T+ L+ F+P
Sbjct: 4296 LFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWT----TDFALPTTVWLAGFFNP 4351
Query: 4184 DTFLNALRQETARAVGRSVDSLKFVASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQ 4238
+FL A+ Q AR +D + + +E + + GL +EG +D
Sbjct: 4352 QSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQT 4411
Query: 4239 LSENQLDSPSVSSVLP-CFMGWIPQDACGPYSPDECISLPVY-TSAERDRVVTNIDVPCG 4296
+ ++ +P F+ IP D + EC PVY T V ++
Sbjct: 4412 GVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC---PVYKTRIRGPTYVWTFNLKTK 4468
Query: 4297 GNQDQWIQCGAALFLK 4312
+WI AL L+
Sbjct: 4469 EKAAKWILAAVALLLQ 4484
Score = 40.8 bits (94), Expect = 0.029
Identities = 51/273 (18%), Positives = 119/273 (43%), Gaps = 24/273 (8%)
Query: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486
L++RP I E+ R +++ L D+ D + + + PL KN+ V +
Sbjct: 531 LMERPLILAEVA-PRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 589
Query: 487 VWVRQLELKVDDTIK----IAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542
W +L+ +++ ++K + ++S + +Q ++++ L+ + ++ + W +
Sbjct: 590 KWSLELQERLEVSMKHLKHVEHPVMSGAEA-KLTYQKYDEMMELLRCHREKIYQQWVAGV 648
Query: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLS-ALGFVIPAKIQ 601
++ D+ L+ V++S LV +LREV+ L+ IP +
Sbjct: 649 DQDCH-------FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAE 701
Query: 602 QVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661
+ + + F K L+ + +YN I + ++++ ++++S L + S ++
Sbjct: 702 SLFSENETFRKFVGNLELIVGWYNEI-KTIVKAVEFLLIKSELEAIDVKLLS-----AET 755
Query: 662 QITWDNPKELEGYIQKLQNAAERLATENRKLRK 694
+ W+ EG Q +Q E L +++K
Sbjct: 756 TLFWNG----EGVFQYIQEVREILHNLQNRMQK 784
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1159 bits (2999), Expect = 0.0
Identities = 948/3556 (26%), Positives = 1647/3556 (46%), Gaps = 284/3556 (7%)
Query: 908 LNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLT--IMPQSVEE 965
L +C P K + I++ + L + L +++ F+ A LT + +
Sbjct: 1062 LQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDG 1121
Query: 966 IGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESH 1025
+ + K++ER+ +F+ + LL+T E I + + +
Sbjct: 1122 LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKL 1181
Query: 1026 QLMIKDQIEVMKGNVKSRLQIYYQELE----KFKARWDQLKPGDDVIETGQHNTLDKSAK 1081
+ +K + ++ N S L+ Q+ E +F+ R+ + P N K
Sbjct: 1182 AIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAP----FSFSDPNPYKSLNK 1237
Query: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141
+ K I + L F + P++ + +++ ++W
Sbjct: 1238 VFLLKGI--------MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSI 1289
Query: 1142 QEMANEDWITFRTKTYLFEEFLMN---WHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILK 1198
EDW T + K E+ ++ + +R +++ + K VI L+
Sbjct: 1290 -----EDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLR 1344
Query: 1199 YV---RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQ 1255
V + + HW L + + S E L DLL++ + + +++++ +A
Sbjct: 1345 AVSELQNPAIRERHWQQLMQATQVKFKMSEETTL-ADLLQL--NLHSYEDEVRNIVDKAV 1401
Query: 1256 GEVTIREALRELDLWGVGAVFTLIDYE-DSQSRT-MKLIKDWKDIVNQVGDNRCLLQSLK 1313
E + + L+ LD + +++++++ + RT ++K + +V + DN+ LQ+L
Sbjct: 1402 KESGMEKVLKALD-----STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLM 1456
Query: 1314 DSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRF 1368
S Y F +V+ W++KL+ D + +QR W +LE IF R LP + RF
Sbjct: 1457 MSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRF 1516
Query: 1369 NRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPR 1428
+ ++++F+++M D K V T+ G+ N L + L C+K+L E+LE KR AFPR
Sbjct: 1517 DDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPR 1576
Query: 1429 FYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF-----DEKSKHITAMKSLEGEV 1483
FYF+ DLL+IL +P + HL KLF + + F D+ K M S E E
Sbjct: 1577 FYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEY 1636
Query: 1484 VPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAE 1543
+ F + LS VE WLN + M TL + E V T +P+QI E
Sbjct: 1637 MVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQIWWTTE 1696
Query: 1544 Q----IKFTEDVENAIKDHSLHQIE--TQLVNKLEQYTNIDTSSEDPGNTESGILELKLK 1597
+ E ENAI+D++ QI L+ L GN +G +K+
Sbjct: 1697 VGLAFARLEEGYENAIRDYNKKQISQLNVLITLLM------------GNLNAGD-RMKIM 1743
Query: 1598 ALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF-YMKSDHTCCVQMVDSEFQYTYEYQ 1656
+ +H DVV ++ V +++ + W+ QLR + + C + D++ QY+YEY
Sbjct: 1744 TICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800
Query: 1657 GNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCD 1716
GN +LV TPLTD+CY+TLTQ++ + +GG P GPAGTGKTE+ K LG LG V VFNC
Sbjct: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860
Query: 1717 EGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLG 1776
E +D KS G I+ GL + GAWGCFDEFNR+ VLS +++Q++ +QDA++ + LG
Sbjct: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920
Query: 1777 KEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFK 1836
+ + + GIFITMNP GY GR +LP+NLK LFRP AM PD ELI E++L +EGF
Sbjct: 1921 EIIGLIPTVGIFITMNP---GYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFL 1977
Query: 1837 DAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESH 1896
+A++L+RK + ++ L +ELL+ Q HYDWGLRA+K+VL +G+L K G A E
Sbjct: 1978 EARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL-----KRGDPSRA-EDQ 2031
Query: 1897 IVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIP 1956
++++ALR + K D F LI D+FP +++ +KQ E +
Sbjct: 2032 VLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAED 2091
Query: 1957 NQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRY 2016
+ + K ++L E L R V IVG +G+GKS + + L + ++PKA+
Sbjct: 2092 SFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCD 2151
Query: 2017 QLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLL 2076
+L G I+ TREW DG+ + R + D WII DGDIDP WIESLN+V+DDN++L
Sbjct: 2152 ELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVL 2211
Query: 2077 TMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL-RNQPA 2135
T+ S ERI + VFE L A+PAT+SR G+++++ + N ++ SW+ R +
Sbjct: 2212 TLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ 2271
Query: 2136 EYRNNLENWIGDYFEKA---LQWVLKQNDYVVETSLVGTVMNGLSHL--------HGCRD 2184
+ NL Y L++ K+ V E +++ T++ L L R+
Sbjct: 2272 SEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRE 2331
Query: 2185 HDE--FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTYYDSTRGR 2237
E F+ GG + +++ E W P D Y D +
Sbjct: 2332 LYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKK 2391
Query: 2238 LATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGK 2297
+ K P D L ++ T + R + YF L + P +LVG G GK
Sbjct: 2392 FLPWTDKVPSFELDPDVP--LQASLVHTTETIR-IRYFMD-LLMEKSWPVMLVGNAGTGK 2447
Query: 2298 GMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLV 2355
+L+ L + + V + TTS L L + + +GR Y P ++LV
Sbjct: 2448 SVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKP---LEKKSGRNYGPPGTKKLV 2504
Query: 2356 LYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN-LEWVGLENIQIVASMSAGGRLGR 2414
++ D+N+P++DK+GT ++Q + ++ +YD + L + N Q VA M+ G
Sbjct: 2505 YFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GS 2562
Query: 2415 HKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMV 2474
+ +R + ++ +P +E L TIY L L + +I SS+ L + +
Sbjct: 2563 FTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQ---LVAAAL 2619
Query: 2475 QVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARR 2533
+++++ A F HY F L+ GL E PLD V + +E R
Sbjct: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAE--VLKTPLDLV-RLWLHETER 2676
Query: 2534 LFRDKIVGAKE---LHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQ 2590
++ DK+V K+ LH + T F D G ++L + F H + P
Sbjct: 2677 VYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFC------HFAQGIGDPKY 2730
Query: 2591 PLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGS 2650
PL KL L DV+ Y N ++++LF + + ++ RI+R+L P G+
Sbjct: 2731 VPVTDMAPLNKL----LVDVLDS----YNEVNAVMNLVLFEDAVAHICRINRILESPRGN 2782
Query: 2651 LLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVL 2710
LL G G G+++++ L +++ G +F + +GY + K DL A ++ V
Sbjct: 2783 ALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVF 2842
Query: 2711 LLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG---PVFNY 2767
L+ D Q FL +IN LL+SGE+PGL+ +E+E ++ ++ Q G + +
Sbjct: 2843 LMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKF 2902
Query: 2768 FTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSET 2827
F ++++ L ++L S + PA+ + W W ++ + ET
Sbjct: 2903 FIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET 2962
Query: 2828 GGGEKYNDKKRKEEKKKNSVDPDFLKSFL--LIHESCKAYGATPSRY-----MTFLH--- 2877
G + K S+ F S++ ++E + Y AT RY TFL
Sbjct: 2963 EG---------IPWEVKASI--SFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIK 3011
Query: 2878 VYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQ 2937
+Y + + K+ EL+ + L+ G+ KL + VD+L K Q LK K + AD +Q
Sbjct: 3012 LYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQ 3071
Query: 2938 MITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKP 2997
++ + + S++K ++ + ++ + E++ + +L + +P + A+ A+ +
Sbjct: 3072 VVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNK 3131
Query: 2998 ESLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAKRGV-REDIATFD 3051
+L+E++S PPD + ++ V+ L D SW + K + K + + FD
Sbjct: 3132 NNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFD 3191
Query: 3052 ARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLET 3111
+I + ++ + ++ +FDP+ + STAAA L +W +++ V + P
Sbjct: 3192 KEHIPEACLKAFKP--YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ 3249
Query: 3112 EQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKA 3171
+ L + +++ +++ + + +S L F+ T+E K + E I
Sbjct: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILL 3309
Query: 3172 AEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEE-WT 3230
A L+ L E+ RW V + TL L +AF++Y+ + R +E+ W
Sbjct: 3310 ANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWI 3369
Query: 3231 K-----------SAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKS 3279
+ GL+ L L +++ W ++GLPSD +S ENA + + +
Sbjct: 3370 PYIHNLKVPIPITNGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATI---LGNTER 3423
Query: 3280 WSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DG 3338
W P ++D Q +W+K + S L+ I +++ +E A+ G TL+I+ + +
Sbjct: 3424 W----PLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGET 3478
Query: 3339 VEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVN 3398
V+PVL PLL R+ + +G ++IGDK ++Y+ +FRL L T+ NP P+ + T +N
Sbjct: 3479 VDPVLDPLLGRNTIKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLIN 3536
Query: 3399 FTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNI 3458
F TR GL QLLA + E+PDLE+ K L + + + KI L +LE+SLL L+ + GN
Sbjct: 3537 FLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNF 3596
Query: 3459 LENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSK 3518
L + L+E+L TK +++ I+E + E+ ++ +++ R+ Y P AE AS +YFI++DL+K
Sbjct: 3597 LGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNK 3656
Query: 3519 INNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMF 3578
IN +Y+FSL AF +F++A+Q + +QR+ +L + + VY Y R LF+ D+L+F
Sbjct: 3657 INPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIF 3716
Query: 3579 ALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKI 3638
FQ V D L + + + P Q + W +
Sbjct: 3717 LAQVT-------FQVLSMKKELNPVELDFLLRFPFKAGVVS--PVDFLQHQGWG-GIKAL 3766
Query: 3639 ALPSLYQTLCFE---DAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQALRPDRLQ 3694
+ ++ L + A W+ + E+E FP K +L Q++ +V+ LRPDR+
Sbjct: 3767 SEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPDRMT 3825
Query: 3695 SAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANA---E 3751
A+ F + +G K V + + Y+E+ I I+SPG DP ++++ L
Sbjct: 3826 YAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFT 3885
Query: 3752 RSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL--------KNLHLVVSWLPVLEKEL 3803
H V++GQGQ +A L A G W+ L +N+HLV WL L+K+L
Sbjct: 3886 IDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKL 3945
Query: 3804 N--TLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTP 3856
+ + +R++++AE P+ +L++++KIT E P G+ NL + + +T
Sbjct: 3946 EHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQ 4005
Query: 3857 E--QISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLF 3914
+ ++ K+ + LF+L +FHA ERR + QGW + Y F+ DL N++
Sbjct: 4006 DTLEMCTKEMEFKC-MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYL 4064
Query: 3915 DGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPY 3974
+ V W+ + L +YGG I + +D R+ ++YL ++ + +++ +
Sbjct: 4065 EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE------GDVLLAP 4118
Query: 3975 SVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILG 4029
+P + Y I++ + P +GL N + +S+++ + + Q +
Sbjct: 4119 GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETD 4178
Query: 4030 RSITAGSKFDREIWSNELSP-------------------------VLNLWKKLNQNSNLI 4064
G + + S +L P + ++ +K+ + N+
Sbjct: 4179 SGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMA 4238
Query: 4065 HQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASA 4124
+ + ++ +++F E+ N L + +SL L+ ++G ++++V+ L++A
Sbjct: 4239 -EIMAKAAEKTPYVVVAFQECERMNI--LTNEMRRSLKELNLGLKGELTITTDVEDLSTA 4295
Query: 4125 LLNQKCPLAWQSK-WEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHP 4183
L P W ++ + + L+ R ++ W L T+ L+ F+P
Sbjct: 4296 LFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWT----TDFALPTTVWLAGFFNP 4351
Query: 4184 DTFLNALRQETARAVGRSVDSLKFVASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQ 4238
+FL A+ Q AR +D + + +E + + GL +EG +D
Sbjct: 4352 QSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQT 4411
Query: 4239 LSENQLDSPSVSSVLP-CFMGWIPQDACGPYSPDECISLPVY-TSAERDRVVTNIDVPCG 4296
+ ++ +P F+ IP D + EC PVY T V ++
Sbjct: 4412 GVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC---PVYKTRIRGPTYVWTFNLKTK 4468
Query: 4297 GNQDQWIQCGAALFLK 4312
+WI AL L+
Sbjct: 4469 EKAAKWILAAVALLLQ 4484
Score = 40.8 bits (94), Expect = 0.029
Identities = 51/273 (18%), Positives = 119/273 (43%), Gaps = 24/273 (8%)
Query: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486
L++RP I E+ R +++ L D+ D + + + PL KN+ V +
Sbjct: 531 LMERPLILAEVA-PRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 589
Query: 487 VWVRQLELKVDDTIK----IAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542
W +L+ +++ ++K + ++S + +Q ++++ L+ + ++ + W +
Sbjct: 590 KWSLELQERLEVSMKHLKHVEHPVMSGAEA-KLTYQKYDEMMELLRCHREKIYQQWVAGV 648
Query: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLS-ALGFVIPAKIQ 601
++ D+ L+ V++S LV +LREV+ L+ IP +
Sbjct: 649 DQDCH-------FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAE 701
Query: 602 QVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661
+ + + F K L+ + +YN I + ++++ ++++S L + S ++
Sbjct: 702 SLFSENETFRKFVGNLELIVGWYNEI-KTIVKAVEFLLIKSELEAIDVKLLS-----AET 755
Query: 662 QITWDNPKELEGYIQKLQNAAERLATENRKLRK 694
+ W+ EG Q +Q E L +++K
Sbjct: 756 TLFWNG----EGVFQYIQEVREILHNLQNRMQK 784
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 1125 bits (2910), Expect = 0.0
Identities = 908/3553 (25%), Positives = 1638/3553 (46%), Gaps = 251/3553 (7%)
Query: 894 KEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAM 953
+E++ L + V L ++ P+K + + LL L + + + + F+ E +
Sbjct: 1047 QEIDELKPIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYL 1106
Query: 954 EVLTIMPQSVEEIGDANLQYSKLQERKPE----ILPLFQEAEDKNRLLRTVAGGGLETIS 1009
+ L+ + ++++ A S +++ + + + P+ + NR V E +
Sbjct: 1107 KKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVD 1166
Query: 1010 NLKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIE 1069
L+ ++K + S Q + K N+ ++++ +++ F ++ P I
Sbjct: 1167 TLRYSFNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIP 1226
Query: 1070 TGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQ 1129
+++ ++ + FDDL F L ++ + K++ +
Sbjct: 1227 P------QEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQK 1280
Query: 1130 IWAFYEEFQQGFQ------------EMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHS 1177
++ Y+ E N + + F+ + + L +W L
Sbjct: 1281 LYGLYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFL------- 1333
Query: 1178 VMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVA 1237
L+ +D + P+L+ + + + HW + L G P + +++
Sbjct: 1334 ----DLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAP 1389
Query: 1238 DTIVAKAADLKDLNSRAQGEVTIREALRE-LDLWGVGAVFTLIDYEDSQSRTMKLIKDWK 1296
++ D++D+ A E I L + ++ W + + + + L+K +
Sbjct: 1390 --LLKHKDDIEDICISAIKEKDIEAKLTQVIENW----TNQNLSFAAFKGKGELLLKGTE 1443
Query: 1297 --DIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEP 1354
+I+ + D+ +L SL + Y F+ + W KL+ + ++ +Q WVYLE
Sbjct: 1444 SGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEA 1503
Query: 1355 IFGRG----ALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTIL-DQLQ 1409
+F G LP+E RF +D+ + IM ++ V LL L +QL+
Sbjct: 1504 VFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLE 1563
Query: 1410 RCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEK 1469
CQKSL +LE+KR FPRF+F+ D LLEILGQ+++ IQ HL + IN V F K
Sbjct: 1564 VCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAK 1623
Query: 1470 S-KHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGA 1528
I A+ S EGE + N V VE WL DL +L +++ S
Sbjct: 1624 DYDRIMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQ 1683
Query: 1529 VDPSL--FPSQILCLAEQIKFTEDVENAIK----DHSLHQIETQ----LVNKLEQYTNID 1578
+ P L FP+Q+ L Q+ +T D E A++ D + Q+ Q ++N L T D
Sbjct: 1684 LLPFLSHFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHD 1743
Query: 1579 TSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD- 1637
S D +K + LI +H D+ L ++ + + D+ W KQ RFY K D
Sbjct: 1744 LSKFD---------RVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDL 1794
Query: 1638 HTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTE 1697
V + D +F Y E+ G +LV TPLTD+CY+TL QA+ M +GG P GPAGTGKTE
Sbjct: 1795 DQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTE 1854
Query: 1698 SVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQ 1757
+ K +G LG+ V+VFNC + +D + +GRIF GL + G+WGCFDEFNR+E VLS + Q
Sbjct: 1855 TTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQ 1914
Query: 1758 IQTIQDALKNHRTVCELL-GKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVA 1816
I + A K + G V++N GIF+TMNP GY GRQ+LP+NLK FR VA
Sbjct: 1915 IYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVA 1971
Query: 1817 MSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGS 1876
M PD ++I V L S GF + +L++K ++ L E LT Q HYD+GLR + +VLR
Sbjct: 1972 MMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTL 2031
Query: 1877 GNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEY 1936
G+ R + +E IV++ LR +SK D F +LI D+FPG++L Y
Sbjct: 2032 GSQKRARPED------SELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTY 2085
Query: 1937 DELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAAL 1996
EL A+ + P K ++LYE R G++ +GPSG+GK+T+ +L A
Sbjct: 2086 AELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQ 2145
Query: 1997 CKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDG 2056
+ G+ ++ MNPKA+ Q+ G +D T +W+DG+ + R+ ++ + + ++I DG
Sbjct: 2146 TECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDG 2205
Query: 2057 DIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLS 2116
+D WIE+LNSVLDDN+ LT+ +G+RI P+ +FE H++ ASPAT+SRMGM+++S
Sbjct: 2206 PVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYIS 2265
Query: 2117 DEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWV---LKQNDYVVETSLVGTVM 2173
++++WL+ + A+ FE ++ L ++E + + +
Sbjct: 2266 SSALSWRPILQAWLKKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSL 2325
Query: 2174 NGLSHLHGCRD----------HDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARES---- 2219
N L L ++ H F+ L+ LG L ++SR + E F ES
Sbjct: 2326 NLLEGLIPSKEEGGVSCVEHLHKLFVFGLMWSLGALLELESREKL--EAFLRQHESKLDL 2383
Query: 2220 ---PPDFHKPMDTYYDSTRGRLATYVLK-KPEDLTADDFSNGLTLPVIQTPDMQRGLDYF 2275
P ++ M +Y + G + K +P D ++ V P++ F
Sbjct: 2384 PEIPKGSNQTMYEFYVTDYGDWEHWNKKLQPYYYPTDSIPEYSSILV---PNVDNIRTNF 2440
Query: 2276 KPWLSSDTKQPFILVGPEGCGKGMLLR-YAFSQLRSTQIATVHCSAQTTSRHLLQKLSQT 2334
+ + +L G +G K ++++ Y Q++ + T + Q+ ++
Sbjct: 2441 LIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIES 2500
Query: 2335 CMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFY--DENL 2392
+ G Y P ++ +++ DIN+P +++WG ++Q++ +G Y D+
Sbjct: 2501 --YVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPG 2558
Query: 2393 EWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYG----AYLEP 2448
++ + ++Q++A+M G GR+ + R + + P + I+G Y +P
Sbjct: 2559 DFTTIVDVQLIAAMIHPGG-GRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDP 2617
Query: 2449 VLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFR 2508
++ K + + + G ++ + +V+ T + HY F L++ G+
Sbjct: 2618 C--RSFKPQICEMIVNLVSV--GRVLWQWTKVKMLPTPSKF-HYIFNLRDLSRIWQGMLT 2672
Query: 2509 YDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILD-N 2567
E +S + +L + +E R+ D+ + ++ F+ LT + + GSD
Sbjct: 2673 IKAEECAS---IPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCI 2729
Query: 2568 MSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRD------ 2621
+ + ++V + P + K + S D + + L Y R
Sbjct: 2730 LPEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDF---LAEKLQFYQRQFNEIIR 2786
Query: 2622 NQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKI 2681
+LD++ F + + ++ +I R++ G+ LL G G G+++++ L S + G +F +
Sbjct: 2787 GTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITL 2846
Query: 2682 SRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTL 2741
+R Y + +DLK + ++AG + + + + D + FLE +N+LLSSGE+ L+
Sbjct: 2847 TRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFAR 2906
Query: 2742 EELEPLLLPL-----KDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESN 2796
+E++ + L ++ F ++ YF R ++NLH+VL F
Sbjct: 2907 DEMDEITQGLISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKF 2966
Query: 2797 PALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFL 2856
P L C + W W ++ + S+ YN E K++
Sbjct: 2967 PGLISGCTMDWFSRWPREALIAVASYFLSD------YNIVCSSEIKRQVVETMGLFHD-- 3018
Query: 2857 LIHESCKAY--------GATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAK 2908
++ ESC++Y TP Y++F++ Y I + K K + ++ + G+ KL EA
Sbjct: 3019 MVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEAS 3078
Query: 2909 ALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIE 2968
V +L++ + L +AD L +TVS Q +++ K E++ +K + + V +I+
Sbjct: 3079 ESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEID 3138
Query: 2969 ERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLM---- 3024
K K + +L+ +P + EA+ A+ IKP ++ +R L PP +I I++ VL L
Sbjct: 3139 SEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKI 3198
Query: 3025 ---------GIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFD 3075
SW ++ G + F I++E E ++ + N +
Sbjct: 3199 DPVTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQP--YFNMDDYT 3256
Query: 3076 PKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLN 3135
++AK+ A L +W A + + + PL+ A E L K + LL+
Sbjct: 3257 FESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLD 3316
Query: 3136 SVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITE 3195
++ +++ KF + +E L + ++ ++AA LI+ L E RW Q E
Sbjct: 3317 EKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKA 3376
Query: 3196 ELATLPKRAQLAAAFITYLSAAPESLRKTCL-EEWTKSAGLEKFDLRRFLCTESEQLI-- 3252
++ L L F++YL + R L ++W + R+ TE+ LI
Sbjct: 3377 QINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEM-----ELRARKIPFTENLNLISM 3431
Query: 3253 ---------WKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLK 3303
W +GLP DDLSI+N +++ + + P LIDP +Q W+K+ K
Sbjct: 3432 LVDPPTIGEWGLQGLPGDDLSIQNGIIVTK-------ATRYPLLIDPQTQGKTWIKSKEK 3484
Query: 3304 DSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQI 3362
++ L+V + F T LE ++ G+ L+I+++ + ++P L +L ++ + G + V++
Sbjct: 3485 ENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKV 3544
Query: 3363 GDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDL 3422
GDK D + F+L+++T+ PNP P+ + + ++FT T GL QLL I EK +L
Sbjct: 3545 GDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQEL 3604
Query: 3423 EEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESL 3482
E ++ KLL+ K ++ +LE++LL L+ ++G++++++ LI L TK ++A + E L
Sbjct: 3605 EAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKL 3664
Query: 3483 KESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQ 3542
+ + +I ++ ++ + P A S +YF+I+++S +N MY+ SLA FL+LF +++ +
Sbjct: 3665 HVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSE 3724
Query: 3543 DSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGV 3602
S ++RI ++I L + V+ Y R L++ + +F L + + + F +
Sbjct: 3725 KSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHRE-FQAL 3783
Query: 3603 VVGD--MLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTL--CFEDAALWRTY 3658
+ G + KA + R WI + +W LP + + + W+++
Sbjct: 3784 IKGGAALDLKACPPKPYR-----WI-LDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSW 3837
Query: 3659 YNNSMCEQE-FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNL 3717
++ E+E P + ++L++++ PDR + +L K P+ LNL
Sbjct: 3838 FDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNL 3897
Query: 3718 KRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKEC 3777
++ ++E+ P++ +S G+DP+ ++ LA + EC ++MGQGQ A ++++
Sbjct: 3898 EKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKL-EC-RTISMGQGQEVHARKLIQMS 3955
Query: 3778 ARNGDWLCLKNLHLVVSWL-PVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKIT 3836
+ G W+ L+N HL + ++ +LE + T D+FR+W+T E H F LLQ+SLK T
Sbjct: 3956 MQQGGWVLLQNCHLGLEFMEELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFT 4015
Query: 3837 YESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFY 3896
E P G++ L RT+ + + + L+++A+ H+ QERR + P GW Y
Sbjct: 4016 NEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPY 4075
Query: 3897 EFSLSDLRAGYNIIDRLFDGA---KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQ 3953
EF+ +D A I D K V W V ++ YGGR+ + FD R+L + +
Sbjct: 4076 EFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARV 4135
Query: 3954 FFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSS 4013
+F+ + + F +P ++ Y I+ +P D P FGL N +
Sbjct: 4136 WFSEKMFE------PSFCFYTGYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITY 4189
Query: 4014 QRMISSQVISQL-RILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPN 4072
Q +S V+ + I + G RE LS ++ KL + I +V
Sbjct: 4190 QSNTASAVLETITNIQPKESGGGVGETREAIVYRLSE--DMLSKL--PPDYIPHEVKSRL 4245
Query: 4073 DRQG--SPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKC 4130
+ G + + F+ E R++ + SL+ L I GT ++S ++ + + +
Sbjct: 4246 IKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARI 4305
Query: 4131 PLAWQS-KWEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNA 4189
P W+ W+ + L+ R W+ + ++ F+P FL A
Sbjct: 4306 PQLWKRVSWDSSTLGFWFTE-LLERNAQFSTWIFEGRPNVFW-----MTGFFNPQGFLTA 4359
Query: 4190 LRQETARA-VGRSVDSLKFVASWKGRLQEAKLQIK--------ISGLLLEGCSFD--GNQ 4238
+RQE RA G ++D+ V L++ K +I I GL ++G ++D +
Sbjct: 4360 MRQEVTRAHKGWALDT---VTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRNGK 4416
Query: 4239 LSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERDRV--VTNIDVPCG 4296
L E+ +P V + ++ P P + P+Y R + +T + +
Sbjct: 4417 LMES---TPKVLFTQLPVLHIFAINSTAPKDP-KLYVCPIYKKPRRTDLTFITVVYLRTV 4472
Query: 4297 GNQDQWIQCGAAL 4309
+ D WI G AL
Sbjct: 4473 LSPDHWILRGVAL 4485
Score = 41.2 bits (95), Expect = 0.023
Identities = 70/373 (18%), Positives = 148/373 (39%), Gaps = 37/373 (9%)
Query: 316 NEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTRVFEP-FTGLNPVQYN 374
+E Y + KRLE++ + T+ + + ++ E I + F + G+ QY+
Sbjct: 354 SEMYIFGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYD 413
Query: 375 PYTEPL---WKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQ--QLLQAFLKYKELVK 429
+P + + I E +I + + +I S Q QLLQ F K +
Sbjct: 414 -ILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQK----LN 468
Query: 430 RPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSIVWV 489
P + E+ E +L V + + + ++ P +N+ + I+WV
Sbjct: 469 IPCLGLEINHTIERILQYYVAELDATKKLYHSQ-------KDDPPLARNMPPIAGKILWV 521
Query: 490 RQLELKVDDTIKI---AEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDIQSGL 546
RQL ++ + I +LS G Q K + L +E W R+I
Sbjct: 522 RQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNK-ISYVLVEFEVVYHTAWIREI---- 576
Query: 547 SDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANI 606
S L + + G L V++ +++ ++RE + + + +P + +++ +
Sbjct: 577 ----SQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKL 632
Query: 607 AQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWD 666
K + L+ + +Y+ + Q++ +M E +++ G + +TW
Sbjct: 633 ESKLKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQ------GLTVLTWS 686
Query: 667 NPKELEGYIQKLQ 679
+ LE + Q+++
Sbjct: 687 S-LTLESFFQEVE 698
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 605 bits (1560), Expect = e-172
Identities = 543/2068 (26%), Positives = 944/2068 (45%), Gaps = 233/2068 (11%)
Query: 770 ENLPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG-------IPNQFKGVGEAGD- 821
+ LP I+LT+ +++F P F+++ ++R IP+ G +
Sbjct: 321 QRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNL 380
Query: 822 -----ESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQV--DMEAL-VE 873
E + +D + + E + + ++ W++ G ++E E
Sbjct: 381 DTELPEHVLHWAVDTLKAA---VHRNLEGARKHYETYVEKYN-WLLDGTAVENIETFQTE 436
Query: 874 KHLFTVH-DWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVL 932
H F + ++ + F +L E+ LP + + ++C +KT + + + ++L+
Sbjct: 437 DHTFDEYTEFIEKFLSL---ASEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLN 493
Query: 933 SL----KKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSK------------L 976
+ +K + E + A++V P++ EE+ D K +
Sbjct: 494 DIASKYRKENECICSEFEAIKEHALKV----PETTEEMMDLISYVEKARTVGIEELILRI 549
Query: 977 QERKPEI---LPLFQEAEDKNRLLRTVA----------GGGLETISNLKAKWDKFELMME 1023
QE K ++ L +F ++ L TV E I N K K + ELM +
Sbjct: 550 QESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKEN-ELMAK 608
Query: 1024 SHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNT--LDKSAK 1081
+L++ E+ K + + + ELE+ + ++ I+ + ++K +
Sbjct: 609 REKLIL----EIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEE 664
Query: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSIS-KDIESCAQIWAFYEEFQQG 1140
L K + ++ +L+ + + F NF L S K + E +
Sbjct: 665 LFKWELTKYPELDKLKVNIEPYQKFF-----NFVLKWQRSEKRWMDGGFLDLNGESMEAD 719
Query: 1141 FQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYV 1200
+E + E F+T + + ++ + + S+ K++ E K I + +
Sbjct: 720 VEEFSRE---IFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEE-PKDNATITMCR-- 773
Query: 1201 RGEHLSPDHWLDLFRLLGLP----RGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQG 1256
+ HW + ++G GT+L K+L +L + + +++ A
Sbjct: 774 ----MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLE-------QFEVISAGASK 822
Query: 1257 EVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSP 1316
E ++ +A+ + F + Y D+ + + + + I++ D Q+++ SP
Sbjct: 823 EFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILD---DQIIKTQTMRGSP 879
Query: 1317 YYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRG----ALPKEQTRFNRVD 1372
+ K FE ++ WE +L + E + +Q +W+YLEPIF +P+E +F VD
Sbjct: 880 FIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVD 939
Query: 1373 EDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFI 1432
+R IM KD +V T+ G+ L + L++ K LN +LE+KR FPRF+F+
Sbjct: 940 RHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFL 999
Query: 1433 GDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPL 1492
+D++LEIL ++ +P +Q HLKK F GI + F + I AM S EGE V +
Sbjct: 1000 SNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEF-LPNLDIKAMYSSEGERVELIALIST 1058
Query: 1493 S---NNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTE 1549
S VE WL + M +++ ++ S +P Q++ Q+ +T
Sbjct: 1059 SAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTS 1118
Query: 1550 DVENAIKD--HSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNI 1607
+ + I L + +L N+L + + + L AL+ +H
Sbjct: 1119 ETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTT------LGALVTIDVHAR 1172
Query: 1608 DVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPL 1667
DVV + ++ V D+ W QLR+Y ++++ V++++ +Y YEY GN+ +LV TPL
Sbjct: 1173 DVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR-VRIINCNVKYAYEYLGNSPRLVITPL 1231
Query: 1668 TDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRI 1727
TD+CY TL A + LGG P GPAGTGKTE+ K L L Q +VFNC +G+D +MG+
Sbjct: 1232 TDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKF 1291
Query: 1728 FVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGI 1787
F GL GAW CFDEFNR+E VLS V+ QI IQ A++ V G E+++N N +
Sbjct: 1292 FKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFV 1351
Query: 1788 FITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVA 1847
ITMNP GY GR +LPDNLK LFR VAM P+ LIAE+ LYS GF +A+ LS K+V
Sbjct: 1352 AITMNP---GYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVM 1408
Query: 1848 IFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTM 1907
+ L E L+ Q HYD+G+RA+K VL +GNL + N NE +++++++
Sbjct: 1409 TYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKY------PNENEDILLLRSIKDVNE 1462
Query: 1908 SKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYE 1967
KF D F+ + D+FPGI+L E +Y E + N + + ++K ++ YE
Sbjct: 1463 PKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYE 1522
Query: 1968 QLCQRMGVVIVGPSGAGKSTLWRMLRAALC--------KTGKVVKQYTMNPKAMPRYQLL 2019
+ R G ++VG A K+ + +L L + KV+ + T+NPK++ QL
Sbjct: 1523 MMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYR-TVNPKSITMGQLF 1581
Query: 2020 GHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMP 2079
G D + EW+DG++ N+ R+ W++ DG ID WIES+N+VLDDN+ L +
Sbjct: 1582 GQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLM 1641
Query: 2080 SGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPA---- 2135
SGE IQ P ++ +FET DLS ASPAT+SR GMI+L + L+ SWL +
Sbjct: 1642 SGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCE 1701
Query: 2136 -EYRNNLENWIGDYFEKAL--QWVLKQNDYVVETSLVGTVMNGL---------------- 2176
EY+ L +L + L Q +Y+ T++V ++ L
Sbjct: 1702 PEYQALLRGLFAWLIPPSLNQRVELFQLNYLY-TTIVSKILKILITFRISNYFKYVPLKT 1760
Query: 2177 --------SHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFT---------KEVFHWARES 2219
H C FI +LI +GG+ + R F K+ + +S
Sbjct: 1761 QCTFIKFFLHQQAC-----FIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDS 1815
Query: 2220 PPDFHKPMD--------TYYDSTRGRLATY-VLKKPEDLTADDFSNGLTLPVIQTPDMQR 2270
+ P D Y +GR + L K +L + + I P M
Sbjct: 1816 VGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLG----DKQIKIQDIIVPTMDT 1871
Query: 2271 GLDYFKPWLSSDTKQPFILVGPEGCGKGMLLR-YAFSQLRSTQIAT--VHCSAQTTSRHL 2327
F LS +P + VGP G GK + ++ + L Q ++ SA+T++ +
Sbjct: 1872 IRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQV 1931
Query: 2328 LQKLSQTCMVISTNTGR--VYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQ 2385
Q ++ + R V+ P ++ ++++ D+N+P L+K+G + L+Q
Sbjct: 1932 -----QNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCG 1986
Query: 2386 GFYD-ENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGA 2444
+YD ++ + L +I+++A+M G GR+ +T R +CSI+ E + I+ +
Sbjct: 1987 HWYDLKDTSKITLVDIELIAAMGPPGG-GRNPVTPRCIRHFNICSINSFSDETMVRIFSS 2045
Query: 2445 YLEPVL--HKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQW 2502
+ L H+ + + G+ ++ G+M + V SHY F ++
Sbjct: 2046 IVAFYLRTHEFPPEYFVIGNQ----IVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRV 2101
Query: 2503 VLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELH-LFDIILTSVFQGDWG 2561
+ G + + ++ H + + + +E R+F D+++ + LF + T
Sbjct: 2102 IRGCLLIERDAVANKHTM---IRLFVHEVLRVFYDRLINDDDRRWLFQLTKTV------- 2151
Query: 2562 SDILDNMSDSFYVTWGARHNSGARAAP--------GQPLPPHGKPLGKL-----NSTDLK 2608
I D+ +SF+ + A G + P + ++ N
Sbjct: 2152 --IKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFS 2209
Query: 2609 DVIKKGLIHYGRDNQ-NLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSL 2667
DV+ + L Y + ++ +++++F VLE++SRI RVL GG+ LL G G GR+++T L
Sbjct: 2210 DVVDQCLDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRL 2269
Query: 2668 VSHMHGAVLFSPKISRGYELKQFKNDLK 2695
+ M +F P+IS+ Y + +++ D+K
Sbjct: 2270 ATSMAKMHIFQPEISKSYGMNEWREDMK 2297
Score = 254 bits (650), Expect = 1e-66
Identities = 227/847 (26%), Positives = 384/847 (45%), Gaps = 56/847 (6%)
Query: 3496 RDAYLPLAESASKMYFIISDLSKINNM--YRFSLAAFLRL--FQRALQNKQDSENTEQRI 3551
R + LA S +KM+ ++SK M +R + +F+ + R + NK S+ E+R+
Sbjct: 2263 RQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSFIAVPVTNRIVDNK--SKILEKRL 2320
Query: 3552 QSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKA 3611
+ L + +Y ICR LF+ D+L+F+ + +E E+ ++ G + K
Sbjct: 2321 RYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLAR-KEIEYQELMFLLTGGVSLK- 2378
Query: 3612 DSQQKIRDQLPSWIDQERSWAVATLKIALPS---LYQTLCFEDAALWRTYYNNSMCEQ-E 3667
S +K D P+W+ Q++SW P+ L Q C E WR Y++ +
Sbjct: 2379 -SAEKNPD--PTWL-QDKSWEEICRASEFPAFRGLRQHFC-EHIYEWREIYDSKEPHNAK 2433
Query: 3668 FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEI 3727
FP+ + K ++ Q+I++++ LRPD++ A+ + LG K V P P +L + Y ++
Sbjct: 2434 FPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCT 2493
Query: 3728 EPILIIISPGADPSQELQELAN-AERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL 3786
P++ ++SPGADP L + AN SG + +++GQGQ +A +M+K G W+CL
Sbjct: 2494 IPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553
Query: 3787 KNLHLVVSWLPVLEK---ELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGL 3843
+N HL VSW+P+LEK + + +FRLWLT+ F +LQ+ +K+T E P GL
Sbjct: 2554 QNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPTGL 2613
Query: 3844 KKNLMRTYES---WTPEQISKKDNTHRA--HALFSLAWFHAACQERRNYIPQGWTKFYEF 3898
+ NL+++Y + PE A LF + +FHA QER+ + P GW Y F
Sbjct: 2614 RLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYGF 2673
Query: 3899 SLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSS 3958
+ SDLR + + + +E + L YGGR+ + +D R+L + L F+N
Sbjct: 2674 NESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNLY 2733
Query: 3959 VIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMIS 4018
+++ + + S + P + DY I+K+P P FGL N+ S +
Sbjct: 2734 IVENPHYKFSPS---GNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQT 2790
Query: 4019 SQVISQLRIL--GRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQG 4076
+ L + G T S +I +LN + + + +K P +
Sbjct: 2791 KTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPS-DFDIEMALRKYPVRYEESM 2849
Query: 4077 SPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQS 4136
+ +L +E+FN L+ ++ +L L K I+G ++ S ++ L+ +LL K P W
Sbjct: 2850 NTVL-VQEMERFN--NLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAK 2906
Query: 4137 KWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETA 4195
+ PL Y+ +AR +Q+W + + LS F FL Q A
Sbjct: 2907 RSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFW-----LSGFFFTQAFLTGAMQNYA 2961
Query: 4196 RAVGRSVDSLKF---VASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSV 4252
R +D L + V + + I GL L+G +D + + +
Sbjct: 2962 RKYTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDL 3021
Query: 4253 LPCFMGWIPQDACGPYSPDECISLPVYTSAERDRVV------TNIDVPCGGNQDQ----W 4302
+P WI + P+Y ++ER + TN + DQ W
Sbjct: 3022 MPII--WIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHW 3079
Query: 4303 IQCGAAL 4309
I+ G AL
Sbjct: 3080 IKRGVAL 3086
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 533 bits (1372), Expect = e-150
Identities = 472/1937 (24%), Positives = 849/1937 (43%), Gaps = 302/1937 (15%)
Query: 2606 DLKDVIKK--GLIHYGR---DNQNLDILLF-HEVLEYMSRIDRVLSFPGGSLLLA----- 2654
+L+D+ K GL+ R +++ + LLF HE DR++ F SL
Sbjct: 2601 NLRDMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFH--DRLIDFTDKSLFYRLLSRE 2658
Query: 2655 -------GRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQ 2707
G G G++T +L ++ L+ IS +FK K V AG++ +
Sbjct: 2659 LENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHAGLKGKP 2718
Query: 2708 VVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG---PV 2764
VL++ + +FLE +N ++SSG +P L+ EL+ + + ++ Q G +
Sbjct: 2719 TVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHMDNRQSL 2778
Query: 2765 FNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLF 2824
++F RI +NLHI +IM +F NC P++ C + W E W ++ +
Sbjct: 2779 LSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLIVANSFL 2838
Query: 2825 SETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKA------------YGATPSRY 2872
E K N + R+ K+K + + IH+S K Y TP+ Y
Sbjct: 2839 KE-----KVNFENRENLKEK------LAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSY 2887
Query: 2873 MTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEA 2932
+ F+ ++ I ++++E+ ++ G+S + EA LV E+ + ++ K E
Sbjct: 2888 LQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKET 2947
Query: 2933 DAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAV 2992
+ ++ + Q + + +++ + +AEEV +E+ K +ELK V P ++A +A+
Sbjct: 2948 ETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVAL 3007
Query: 2993 GNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDA 3052
+ ++E+R PP ++ ++ V L+ +W + K L++ G + + D
Sbjct: 3008 NALDKADVAELRVYTRPPFLVLTVMNAVCILLQK-KPNWATAKLLLSETGFLKKLINLDK 3066
Query: 3053 RNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETE 3112
+I ++ +++++ F+P S A L WV A Y V + + P + +
Sbjct: 3067 DSIPDKVFVKLKKIV--TLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQ 3124
Query: 3113 QAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAA 3172
A ++ LK R + + L V + + L+ ++ +E L + A + A
Sbjct: 3125 VAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCA 3184
Query: 3173 EVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKS 3232
VL+ L+ E RW + +I +L + L+AA I Y R+ + +W
Sbjct: 3185 SVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVNKWETF 3244
Query: 3233 A---GLE---KFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPF 3286
G+ KF L + + + E W ++GLP S+ENA++I + W P
Sbjct: 3245 CIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNG---QQW----PL 3297
Query: 3287 LIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DGVEPVLYP 3345
LIDP QA +W++ ++ SRL+ ++ +DSN+ +E A++ G ++++Q + + + P L
Sbjct: 3298 LIDPHRQAHKWIR-QMEGSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKA 3356
Query: 3346 LLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSG 3405
+L++D+ + Y +++GD +YN FRL+LST NP P + VT +NFT T G
Sbjct: 3357 ILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQG 3416
Query: 3406 LRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLI 3465
L+ QLL+ + HE P LE+Q++KLL+ I L +LEE L L + G+IL++ ++
Sbjct: 3417 LQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIV 3476
Query: 3466 ESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRF 3525
++L ++K +S I + ++ + K + + R YLP+A + +YF+++DL++IN MY+F
Sbjct: 3477 DTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQF 3536
Query: 3526 SLAAFLRLFQRALQNKQDSEN-------------------------------TEQRIQSL 3554
SL F ++F ++ +K + ++ I+S
Sbjct: 3537 SLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSA 3596
Query: 3555 ISSLQHMVYEYICRCLFKADQLMFALHFV-----RGMHPELFQ-------ENEWDTF--T 3600
I L +++ + LF D+L F+ + L Q E EW+ F +
Sbjct: 3597 IDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYS 3656
Query: 3601 GVVVGDMLRKADSQQKI-------RDQLPSWIDQERSWAVATLKIALPSLYQTLC---FE 3650
G+++ ++ A SQ ++ Q W+ R W + LC
Sbjct: 3657 GILIN--IKSALSQSRLTSTFEIGESQHLQWLSDSR-WRQCQYVSTHLEPFSLLCKSLLS 3713
Query: 3651 DAALWRTYYNN----SMCEQEFPSILA-----------------------------KKVS 3677
+ + W T+ N+ S+ F S A +K++
Sbjct: 3714 NVSQWDTFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLT 3773
Query: 3678 LFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPG 3737
FQ++++V+ LRP+ L +++ F + +G K + +NLK YK + P+++I + G
Sbjct: 3774 SFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHG 3833
Query: 3738 ADPSQELQELANAERSGECYHQ--VAMGQGQADLAIQM-LKECARNGDWLCLKNLHLVVS 3794
D + L A E G +H +++G+ QA A + LK + W+ L+N HL S
Sbjct: 3834 IDLTNILLRFAQ-ELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATS 3892
Query: 3795 WLP---VLEKELN----TLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNL 3847
++P + + N T+ P+ FRLWL+++ + +F +L+ LKI ESP GLK NL
Sbjct: 3893 FMPRLCTIVESFNSPNVTIDPE--FRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNL 3950
Query: 3848 MRTY----ESWTPEQISKKDNTHR--AHALFSLAWFHAACQERRNYIPQGWTKFYEFSLS 3901
++T+ E+I + + + LFSL +F+A ER+NY GW Y+F+ S
Sbjct: 3951 LQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSS 4010
Query: 3902 DLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVID 3961
DL +++ G + W+ + L+ IYGGR+ + +D R L++ L +F N V+
Sbjct: 4011 DLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVL- 4069
Query: 3962 VFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQV 4021
K F +S +S SI DY +I+ +P+DD P G+ RS +
Sbjct: 4070 -------KDDFSFS----RSASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKF 4118
Query: 4022 ISQLRILGRSITAGSKFDR------EIWSNELSPVL------------------------ 4051
I L + T + R E+ LS +L
Sbjct: 4119 IENLIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMM 4178
Query: 4052 --NLWKKLNQN----SNLIHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALS 4105
++W+ L++N LIH +L+F+ E +L+ +H+SL L
Sbjct: 4179 SSSIWESLSKNLKDHDPLIH-----------CVLLTFLKQEIKRFDKLLFVIHKSLKDLQ 4227
Query: 4106 KVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPL-QYLRGLVARALAIQNWVDK 4164
I+G +L+ E++++ ++ LN + P WQ PL ++ L+ R W
Sbjct: 4228 LAIKGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKV 4287
Query: 4165 AE--------------KQALLSETLD--------------------LSELFHPDTFLNAL 4190
A KQ++ S + L F P FL A+
Sbjct: 4288 AYTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAV 4347
Query: 4191 RQETARAVGRSVDSLKFV--------------------------ASWKGRLQEAKLQIKI 4224
Q+ R+ G +VD+L F ++KG + + I
Sbjct: 4348 LQDYGRSRGIAVDALTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGS-ASSHTGVYI 4406
Query: 4225 SGLLLEGCSFDGNQ-LSENQL------DSPSVSSVLPCFMGWIPQDACGPYSPDECISLP 4277
GL +EG ++ Q + E+ L D P + + P + S P
Sbjct: 4407 FGLFIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFECP 4466
Query: 4278 VYTSAERDRVVTNIDVP 4294
VY + ER R++ +P
Sbjct: 4467 VYQTPERSRILATTGLP 4483
Score = 516 bits (1329), Expect = e-145
Identities = 385/1314 (29%), Positives = 635/1314 (48%), Gaps = 157/1314 (11%)
Query: 922 LIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKP 981
LIQ + + +L + +++ L +++ TE E L E N SK+ + +
Sbjct: 794 LIQSVIEKKNKNLLEVVESSLQQLECDPTEIEEFL-------EHFIFLNAISSKISKLEK 846
Query: 982 EILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGNVK 1041
E L + Q ++ + L K+ + + M+ ++ I + N++
Sbjct: 847 EFLTMSQLYSVAKHHQIHISEEQIAIFQVLLLKFSQLKSSMKLSKINKDTAITKFRDNLE 906
Query: 1042 SRLQIYYQELEKFKAR---------WDQLKPGDDVIET--GQHNTLDKSAKLIKEKKIEF 1090
+ + + ++ KA+ Q+ ++I+T G+ +L AK + F
Sbjct: 907 ACISGLHVDVGNLKAKIRTPLLLCAGTQVSTAMEMIQTLSGEAASLTNKAKAYSHYQDCF 966
Query: 1091 DDLEVTRKKLVDDCHHFRLEEPNFSLASSISK---DIESCAQIWAFYEEFQQGFQEMANE 1147
D + H +EE + S IS D+ ++W EE+++ E N
Sbjct: 967 SDSQ-------SHMHSVNVEEITQIVLSEISDIEGDLTLRKKLWEAQEEWKRASWEWRNS 1019
Query: 1148 DWITFRTKTYLFE-EFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLS 1206
+ ++ LM+ L K S M L+ V ++K +PI+ + L
Sbjct: 1020 SLQSIDVESVQRNVSKLMHIISVLEKGLPKSDMVTHLKQVVTEFKQELPIIIALGNPCLK 1079
Query: 1207 PDHWLDLFRLLG----LPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIRE 1262
P HW L ++G L + +E LL + + + ++ D+++ A E + +
Sbjct: 1080 PRHWEALQEIIGKSVPLDKNCKVENLLALKMFQYEN-------EINDMSTSATNEAALEK 1132
Query: 1263 AL-RELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGF 1321
L + +D W + ++ + + S + +I DI Q+ +++ +L ++K SP+
Sbjct: 1133 MLFKIIDFWNTTPLPLILHHTEIYS--IFIIPSIDDISAQLEESQVILATIKGSPHIGPI 1190
Query: 1322 EDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG----RGALPKEQTRFNRVDEDFRS 1377
+D V+ W++ L L+ + QR W+YLEP+F R LP E F++V ++
Sbjct: 1191 KDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHSSEIRRQLPAETELFSQVISMWKK 1250
Query: 1378 IMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDL 1437
IM+ I+ +TT AG+ L L+ +KSL ++LE KR FPRFYF+ + +L
Sbjct: 1251 IMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAEL 1310
Query: 1438 LEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSL---EGEVVPFKNKVPLSN 1494
L+IL S NP +Q HL K F I + ++ A+K L EGE + K+ + +
Sbjct: 1311 LDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPPAVKMLISAEGEGLVLPKKIRVRS 1370
Query: 1495 NVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTED-VEN 1553
VE WL + ++K++ +LK+ + IL QI F D V++
Sbjct: 1371 AVEQWL----VNVEKSMFDVLKK-------------ERYIYNIILLFQSQIMFYNDCVKS 1413
Query: 1554 AIKDHS---LHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVV 1610
+ +S L ++ L+ LE+ ++ T++ L AL++ +H D+V
Sbjct: 1414 FVSSYSREKLEKVHAGLMCHLEEVADLVVLDTSNSRTKA-----ILGALLILYVHCRDIV 1468
Query: 1611 KQLNQIQVHTTEDWAWKKQLRF-YMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTD 1669
L + ED+ W + L++ + + C V ++ F Y YEY G S+LV TPLTD
Sbjct: 1469 INLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNASFTYGYEYLGCTSRLVITPLTD 1528
Query: 1670 KCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFV 1729
+C+LTL +A+ + LGG P GPAGTGKTE+VK L LG+ +VFNC E +D K + + F
Sbjct: 1529 RCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFF 1588
Query: 1730 GLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFI 1789
GLV+ GAW CFDEFN ++ VLS ++ QI TI+ A N+ L GKE+ +N + +FI
Sbjct: 1589 GLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNYSARFVLEGKEIRINMSCAVFI 1648
Query: 1790 TMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIF 1849
TMNP YGG +LPDNLK LFRPVAM P ++IAE+IL+S GFK A LS KL ++
Sbjct: 1649 TMNPR---YGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLY 1705
Query: 1850 NLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSK 1909
L+R+ L+ Q HY++GLR+LK VL +G R+ A+E+ IV++A+R ++ K
Sbjct: 1706 ELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFK---CLSEADETLIVIEAIREASLPK 1762
Query: 1910 FTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQL 1969
D F+ +I D+FP + + +V L + ++ + +Q +K ++ Y QL
Sbjct: 1763 CPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSSQKEKIIQFYNQL 1822
Query: 1970 CQRMGVVIVGPSGAGKSTLWRMLRAALC---------------------KTGKVVKQYTM 2008
+GV++VGP+G GK+T+ R+L AL + GK V +
Sbjct: 1823 QVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSASKISERKGK-VDICVL 1881
Query: 2009 NPKAMPRYQLLGHIDMDTREWSDGVLTNSAR----------------------------- 2039
NPK + +L G +D +T EW+DG+L+ + R
Sbjct: 1882 NPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDIDLRLKSRISDLSNV 1941
Query: 2040 --------------------QVVREPQDVS---SWIICDGDIDPEWIESLNSVLDDNRLL 2076
+VV+ P++ + WII DG +D W+E+LNSVLDD R L
Sbjct: 1942 FKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFWVENLNSVLDDTRTL 2001
Query: 2077 TMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL 2130
+ + ERI + +FE +LS ASPAT+SR M+++ + +KSWL
Sbjct: 2002 CLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWEPYVKSWL 2055
Score = 60.5 bits (145), Expect = 4e-08
Identities = 59/246 (23%), Positives = 117/246 (47%), Gaps = 19/246 (7%)
Query: 2310 STQIATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKW 2369
ST + + +A T +L+KL I + PK+ R+++++ D+N+P D +
Sbjct: 2428 STINFSTNVTAAKTKEMILKKL------IRRTKDTLGAPKN-NRILIFIDDMNMPVSDMY 2480
Query: 2370 GTSTLVAFLQQVLTYQGFYD-ENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLC 2428
G + ++Q+L G YD E W ++++ IVA+ +L F+ +V
Sbjct: 2481 GAQPPLELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVNDISPRLLKHFSMLV--- 2537
Query: 2429 SIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAK-FTVD 2487
+ +P ++ L TI+ A+L ++ ++ N + SK +++ S+ +Y QVR
Sbjct: 2538 -LPHPSQDILCTIFQAHLG--IYFSINNFTPEVQKSKDQIISCSLA-IYHQVRQNMLPTP 2593
Query: 2488 DYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHL 2547
HY F + + +LGL + D +S + + +EA R+F D+++ + L
Sbjct: 2594 TKCHYMFNLRDMFKLLLGLLQADRTVVNSK---EMAALLFVHEATRVFHDRLIDFTDKSL 2650
Query: 2548 FDIILT 2553
F +L+
Sbjct: 2651 FYRLLS 2656
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 235 bits (599), Expect = 8e-61
Identities = 202/827 (24%), Positives = 377/827 (45%), Gaps = 57/827 (6%)
Query: 3513 ISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFK 3572
++DLSKI+ MY+FSL AF +FQ+A++ E+ +R+ +LI S+ VY+Y R LF+
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3573 ADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWA 3632
D+L + FQ + V D L ++ Q P ++W
Sbjct: 61 CDKLTYLAQLT-------FQILLMNREVNAVELDFLLRSPVQTGTAS--PVEFLSHQAWG 111
Query: 3633 VATLKIALPSLYQTLCFE---DAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALR 3689
+ ++ + L + A W+ + + E+E K + Q++ +++A+R
Sbjct: 112 AVKVLSSMEE-FSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMR 170
Query: 3690 PDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELAN 3749
PDR+ A+ F + LG K V L+ ++E+ P+ I+SPG DP ++++
Sbjct: 171 PDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGR 230
Query: 3750 A---ERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKEL--N 3804
+ + +H V++GQGQ +A L A+ G W+ L+N+HLV WL LEK+L +
Sbjct: 231 KLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEH 290
Query: 3805 TLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQI 3859
+ FR++++AE P+ +L++S+KIT E P G+ NL + +++T + +
Sbjct: 291 SENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTL 350
Query: 3860 SK-KDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAK 3918
T LF+L +FHA ERR + PQGW + Y F+ DL N++ +
Sbjct: 351 EMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANA 410
Query: 3919 DVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSL 3978
V ++ + L +YGG I + +D R+ ++YL +F +++ + S+ P L
Sbjct: 411 KVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLE-----GELSLAP-GFPL 464
Query: 3979 PQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILGRSIT 4033
P + Y I+ + P +GL N + ++S+++ + + Q R
Sbjct: 465 PGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDG 524
Query: 4034 AGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFNAIRL 4093
AG+ + ++ + + + +++ N I + + +R +++F + N L
Sbjct: 525 AGATREEKV----KALLEEILERVTDEFN-IPELMAKVEERTPYIVVAFQECGRMNI--L 577
Query: 4094 VQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSK-WEGPEDPLQYLRGLV 4152
+ + +SL L ++G ++S ++ L +AL P +W + + + L+
Sbjct: 578 TREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLL 637
Query: 4153 ARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWK 4212
R ++ W + T+ L+ F+P +FL A+ Q TAR +D +
Sbjct: 638 NRIKELEAWTG----DFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMT 693
Query: 4213 GRLQE-----AKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLP-CFMGWIPQDACG 4266
+ +E + I GL +EG +D + ++ +P F+ IP D
Sbjct: 694 KKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQD 753
Query: 4267 PYSPDECISLPVYTSAER-DRVVTNIDVPCGGNQDQWIQCGAALFLK 4312
S C PVY +++R V ++ N +W+ G AL L+
Sbjct: 754 CRSVYSC---PVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQ 797
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 204 bits (518), Expect = 2e-51
Identities = 252/1199 (21%), Positives = 478/1199 (39%), Gaps = 178/1199 (14%)
Query: 1101 VDDCHH----FRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITF---- 1152
+ + HH F +E L ++ I +IW Y + E + F
Sbjct: 988 LSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAM 1047
Query: 1153 ---RTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDH 1209
+T+ +L E M+ +E HS + + +++ +P+L + H +
Sbjct: 1048 AQEKTEGWLTEAARMS-----TTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSLN 1102
Query: 1210 WLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADL--KDLNSRAQGEVTIREALREL 1267
L R LGL ++E L G LL A + ++ N R + TIR R
Sbjct: 1103 CQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYW 1162
Query: 1268 DLWGVGAV-FTL-IDYEDSQSRTMK-------------------LIKDWKDIVNQVGDNR 1306
+ + + F L + YE S K ++ D+ ++ + + ++
Sbjct: 1163 EARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESL 1222
Query: 1307 CLLQSLKDSPYYKGFEDKVSI-WERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQ 1365
+L + + G +K+++ W + L L+ Q+KW++L + +
Sbjct: 1223 QVLSKIL-AIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVLHEMKIQFPN 1281
Query: 1366 ----TRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRN------SLLTILD----QLQRC 1411
+RF +D+ +R++M D V +L + R+ L +L +L+
Sbjct: 1282 ADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGI 1341
Query: 1412 QKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF----- 1466
SL L + FPR +F+ D +L+ +L Q +++ F +++V F
Sbjct: 1342 IMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFRSCPT 1401
Query: 1467 ------DEKSKHIT-------AMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQ 1513
D +S T A+ GE V + +PL ++ WL L ++ L
Sbjct: 1402 GEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVH 1461
Query: 1514 LLKECVTTGRSSQGAVDPSL------------------------FPSQILCLAEQIKFTE 1549
+L+ CV + ++ +L FP Q + +AE++ +
Sbjct: 1462 MLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEVVWRA 1521
Query: 1550 DVENAIKDHSLHQIETQLVNKLEQYTNI---DTSSEDPGNTESGILELKLKALILDIIHN 1606
++E A+ + + + + KLE N +S+ + S L AL++ + +
Sbjct: 1522 EMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTH 1581
Query: 1607 IDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDH-----------------------TCCVQ 1643
D+ + L Q QV D+ W +QL++++ S H C +
Sbjct: 1582 RDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWID 1641
Query: 1644 MVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALG 1703
++ F Y YEY G + + L ++ L L A++ G GP G GK V +L
Sbjct: 1642 VLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLA 1701
Query: 1704 GLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTI-- 1761
LGRQ+++ C I+ + + G ++ GAW ++ ++L +LSA+ ++ +
Sbjct: 1702 QALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHH 1761
Query: 1762 ------QDALKNHRTV----CELLGK------EVEVNSNSGIFITMNPAGKGYGGRQKLP 1805
Q+A +N T+ +LLG V V G + + +P
Sbjct: 1762 LYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSA------VP 1815
Query: 1806 DNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWG 1865
NL L RPVA++ PD +AE+ L G +DA ++ +L F+L REL++
Sbjct: 1816 ANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGP--LPCR 1873
Query: 1866 LRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQA--LRLNTMSKFTFTDCTRFDALIK 1923
L LK +L + L + Q + +A LR S L+
Sbjct: 1874 LPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNLRGLLC 1933
Query: 1924 DVFPG---IELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGP 1980
+FP + + + Y + + + ++ + P+ + +L + L + G++++GP
Sbjct: 1934 ALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGP 1993
Query: 1981 SGAGKSTLWRML------RAALCKTG----KVVKQYTMNPKAMPRYQLLGHIDMDTREWS 2030
+G+GK+T W L AA+ T + V+ + P + + LG ++ W
Sbjct: 1994 AGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEGSC--WH 2051
Query: 2031 DGVLTNSAR-----------QVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMP 2079
G+ R + E + WIICDG + W++S+ +L + L++P
Sbjct: 2052 HGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLP 2111
Query: 2080 SGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYR 2138
SG++I P + E D + SP + +++ E+T ++ + + + P EYR
Sbjct: 2112 SGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQT-WQCILSALMASLPYEYR 2169
Score = 90.1 bits (222), Expect = 4e-17
Identities = 158/728 (21%), Positives = 287/728 (39%), Gaps = 87/728 (11%)
Query: 2631 HEVLEYMSRIDRVLSFPGG-SLLLAGRSGVGRRTITSLVSHMHGAVLFS-PKISRGYELK 2688
H + ++++R+ RVL+ P LLL+G G GR T +L S + A F P S L+
Sbjct: 2866 HSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQ 2925
Query: 2689 QFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPL- 2747
++ H AG+ +Q V LL+ V T L + +L +SG PG YT +L+ +
Sbjct: 2926 CLRDASWH----AGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQYTEADLDRIG 2979
Query: 2748 -LLPLKDQASQDGFFGP-VFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHK--KC 2803
LP ++ + V F ++ +LH+ ++ ++ + L +
Sbjct: 2980 EHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATA 3039
Query: 2804 QVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCK 2863
+ E W +++ K+ + E +D K + S+ P K+ LIH S
Sbjct: 3040 SIDRYEPWDQAALAKVAQHHL-EGAQSVPLDDGSWKYPDLQASI-PSVAKAMALIHLSAT 3097
Query: 2864 AYG---------ATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDEL 2914
Y TP ++ FL + + +++ +LK ++ Q + L + L+ E
Sbjct: 3098 HYHEHLCPALPLVTPKTFLDFLDTFLML---QQQTILKIKNKAQRVQNALENLRMLIKEH 3154
Query: 2915 NRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVK-IEERKNK 2973
A L + +D + Q K +LE +H+ E +++ + +++
Sbjct: 3155 GTHANLIFDLEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQ--ENLIENLARQRDA 3212
Query: 2974 IDDELKEVQPLVNEAKLA-VGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWV 3032
+ + + +++A L + ++ EIRS R PP+ + + + + L +T W
Sbjct: 3213 LQAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFH-HETGWA 3271
Query: 3033 SMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAW 3092
S K L +++ F I+ E ++ L D + S AA LAAW
Sbjct: 3272 SAKQLLCTEDFYQELVFFPKEKITDS--ELIKLHLILKAPGMDDAALRAVSRPAASLAAW 3329
Query: 3093 VKANIQYSHVLERIHPLETEQAGLESNLKKTEDR----KRKLEELLNSVGQKVSELKEKF 3148
+ A + Y R P + +E+ L + + R + + +E L ++++ E
Sbjct: 3330 LWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEH-NLALAKMVEDA 3388
Query: 3149 QSRTSEAAKLEAEVSKAQE---TIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQ 3205
Q+ + AK ++ Q +KAA L + W Q+ ++ T+
Sbjct: 3389 QASHNCVAKTLSQAQCGQYHKWPMKAA------LLTPMRAWTTQLQKLKGRCMTVFGDTL 3442
Query: 3206 LAAAFITYLSAAPESLRKTCLEEW-----------------------TKSAGL------- 3235
L +A I YL P R+ L+EW KS +
Sbjct: 3443 LCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLL 3502
Query: 3236 ---EKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKS--WSRVCPFLIDP 3290
F + L +ESEQ W P + L++ S W P L+DP
Sbjct: 3503 ATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRW----PLLLDP 3558
Query: 3291 SSQATEWL 3298
S++A WL
Sbjct: 3559 SNEALIWL 3566
Score = 73.2 bits (178), Expect = 5e-12
Identities = 144/652 (22%), Positives = 247/652 (37%), Gaps = 79/652 (12%)
Query: 3622 PSWIDQERSWAVATLKIALPSLYQTLCFEDA---ALWRTYYN-NSMCEQEFPSILAKKVS 3677
P+W+ ++W + LP + LC A + W+ Y + +S P + +S
Sbjct: 3979 PAWLGP-KAWHECEMLELLPP-FVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLS 4036
Query: 3678 LFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNL---KRLYKETLEIEPILIII 3734
L Q++++ + LRP+ L A+A F LG PL N +K + +P+LI++
Sbjct: 4037 LLQKLILWRVLRPECLAGALADFTTSLLG----RPLDENTYAPTMPFKHSQATQPMLILL 4092
Query: 3735 SPGADPSQELQELANAERSGECYHQ-------VAMGQGQAD---LAIQMLKECARNGDWL 3784
P PS L L ++ Y Q +A+G D + + L + G WL
Sbjct: 4093 PPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWL 4152
Query: 3785 CLKNLHLVVSW-----------------LPVLEKELNTLQPKD--------TFRLWL--T 3817
L N HL+ W + LE E QP+ FRLWL
Sbjct: 4153 VLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVP 4212
Query: 3818 AEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWF 3877
AE + +L Q S+ + + L L+ + E +Q+ +A L L
Sbjct: 4213 AESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVE--LAQQVLYMQPPTQALPLLLL--- 4267
Query: 3878 HAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGR 3937
H R+ Y + +S L D+L+ + + + L + YGG
Sbjct: 4268 HGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPR-AAMQELAASVFYGGP 4326
Query: 3938 IDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLP---QSCSILDYRAVIEKI 3994
+ + D L S + + S +S+ + LP + ++ + +A + +
Sbjct: 4327 LGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAECKAQMHLL 4386
Query: 3995 PEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILGRSITAGSKFDREIWSNELSP 4049
P +P GL + R S+ ++S+ S + S +R + +
Sbjct: 4387 PSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQV 4446
Query: 4050 VLNLWKKLNQNSNLIHQ-------KVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLA 4102
L + +++I Q V PN R+ P+ + E +LV ++ + L
Sbjct: 4447 NRRLESLQDLLTHVIRQDESDAPWSVLGPNARR--PLEGVLETEALELSQLVGTLQRDLD 4504
Query: 4103 ALSKVIRGT-TLLSSEVQKLASALLNQKCPLAWQSKW-EGPEDPLQYLRGLVARALAIQN 4160
L + ++G S +A AL + PL W+ GP+ P +LR L R +
Sbjct: 4505 CLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVR 4564
Query: 4161 W--VDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVAS 4210
+ V + LS HP L ALR E A+ ++V S F S
Sbjct: 4565 YLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEA--ALDQNVPSSNFPGS 4614
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 57.4 bits (137), Expect = 3e-07
Identities = 143/701 (20%), Positives = 275/701 (39%), Gaps = 93/701 (13%)
Query: 2887 KKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKT----------KQDEADAAL 2936
+K + K++ + +L+E +A + ++ + EQ L+K + DE L
Sbjct: 1398 QKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQL 1457
Query: 2937 QMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK 2996
Q+ M+ E+ E R K +I K++ + LKE + L E LA G I+
Sbjct: 1458 QVELCEMKQKPEEIGEESRAKQQIQR---KLQAALISRKEALKENKSLQEELSLARGTIE 1514
Query: 2997 --PESLSEIRSLRMPPDVIRDILEGVL--------RLMGIFDTSWVSMKSF--------L 3038
+SL+++ S + +D + G L +L+ D S + +S L
Sbjct: 1515 RLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKL 1574
Query: 3039 AKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQ 3098
A G+ ED + KEI ES++ + K+ + L ++ + +
Sbjct: 1575 ALEGLTED-----KEKLVKEI-ESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNE 1628
Query: 3099 YSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTS----- 3153
+ + + E+ L L+ TE K++ E+ L Q++ E+KEK +
Sbjct: 1629 AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQK 1688
Query: 3154 ------EAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLA 3207
E +L AEV A +T K + L + ++ + E TL K+ Q
Sbjct: 1689 ILELEEENDRLRAEVHPAGDTAKEC---METLLSSNASMKEELERVKMEYETLSKKFQSL 1745
Query: 3208 AAFITYLSAAPESLRKTCLEEWTKSAGL---EKFDLRRFLCTESEQLIWKSEGLPSDDLS 3264
+ LS + L+ +K A L EK D + + E Q I E D LS
Sbjct: 1746 MSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSI-PGETEEQDSLS 1804
Query: 3265 IENALVILQII-GLKSWSRVCPFLIDPSSQATEWLK--THLKD--SRLEVINQQDSNFIT 3319
+ + + KS + + +L+ LK+ + LE Q++ F
Sbjct: 1805 MSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQ 1864
Query: 3320 ALE---------LAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYN 3370
LE ++ + G+ ++QE E LL + + + R K+ +
Sbjct: 1865 TLENEKNTLLSQISTKDGELKMLQE----EVTKMNLLNQQIQEELSRVT-----KLKETA 1915
Query: 3371 EEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEK---PDLEEQKT 3427
EE + L R N + + + T + ++ +LL +++ K +LEE+K
Sbjct: 1916 EEEKDDLEERLMNQLAELNGS--IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1973
Query: 3428 KLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYK 3487
+L++++ + ++ K ++ GN K+L E L++E +E +
Sbjct: 1974 QLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQE----------LLKEKQQEVKQ 2023
Query: 3488 LQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLA 3528
LQ + ++ L + + F+ ++ K + + +LA
Sbjct: 2024 LQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLA 2064
Score = 45.4 bits (106), Expect = 0.001
Identities = 66/313 (21%), Positives = 134/313 (42%), Gaps = 36/313 (11%)
Query: 830 DRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQVDM---EALVEKHLF----TVHDW 882
D N+S F + + + L ++ + + + Q++M EA ++ L T HD
Sbjct: 733 DNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHD- 791
Query: 883 EKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHL 942
N +I +E VK++ L + V+ + +L +S+Q+ L
Sbjct: 792 --NLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQS---------TLIRSLQSQL 840
Query: 943 HEIDTFVTEAMEVLTIMPQSVEEIGDA----NLQYSK----LQERKPEILPLFQEAEDKN 994
++ V E E + + VEE+ A L+ +K L E+K ++ L Q E+K+
Sbjct: 841 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKD 900
Query: 995 RLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELE-- 1052
+ + ++ E + L +KF L +E L K+Q+ ++ +++ + ++ E
Sbjct: 901 QQVTEISFSMTEKMVQLNE--EKFSLGVEIKTL--KEQLNLLSRAEEAKKEQVEEDNEVS 956
Query: 1053 -KFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEE 1111
K +D++ P + + + D K +++K + + RK+L+ RLEE
Sbjct: 957 SGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS--RLEE 1014
Query: 1112 PNFSLASSISKDI 1124
+L K+I
Sbjct: 1015 ELANLKDESKKEI 1027
Score = 43.9 bits (102), Expect = 0.003
Identities = 70/350 (20%), Positives = 144/350 (41%), Gaps = 48/350 (13%)
Query: 2892 KRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLK--TKQD----EADAALQMITVSMQD 2945
++Q + + + NE L+ +++ K GE +L + TK + + L +T +
Sbjct: 1855 EKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKET 1914
Query: 2946 ASEQKTELE-RLKHRIAE----------EVVKIEERKNKIDDELK-----------EVQP 2983
A E+K +LE RL +++AE +V + + ++ E+K E Q
Sbjct: 1915 AEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQ 1974
Query: 2984 LVNEAKLAVGNIKPESLSEIRSLRMPP----------DVIRDILEGVLRLMGIFDTSWVS 3033
LV E I+ E L +I+ + P +++++ + V +L D
Sbjct: 1975 LVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK--DCIRYQ 2032
Query: 3034 MKSFLAKRGVR--EDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAA 3091
K +R V+ E + T +++ + + + K + + K AA
Sbjct: 2033 EKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAA 2092
Query: 3092 WVKANIQYSHVLERIHPLETEQAGLESNLK-KTEDRKRKLEELLNSVGQKVSELKEKFQS 3150
V A+ L+ L++ + ++S +K K ED +R+LE+ ++ ++EK +
Sbjct: 2093 RVLADN-----LKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDA 2147
Query: 3151 RTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATL 3200
E LE + + Q T+ + + QL Q+ T+ +++L
Sbjct: 2148 LRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL 2197
Score = 42.0 bits (97), Expect = 0.013
Identities = 133/730 (18%), Positives = 276/730 (37%), Gaps = 101/730 (13%)
Query: 2906 EAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVV 2965
E + L +L + +LK K E + L+ ++ +QK + RL+ + E+
Sbjct: 1172 EKEQLQKKLQEALTSRKAILK-KAQEKERHLR------EELKQQKDDYNRLQEQFDEQ-- 1222
Query: 2966 KIEERKNKIDDELKEVQPLVNEA---KLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLR 3022
+ I D+L+++Q V E+ KL + + ES S L P +
Sbjct: 1223 --SKENENIGDQLRQLQIQVRESIDGKLPSTD-QQESCSSTPGLEEPLFKATEQHHTQPV 1279
Query: 3023 LMGIFDTSWVS-------MKSFLAKRGVREDIATFDARNISKEIRES--VEELLFKNKGS 3073
L W S ++ + ++ + +A + E++ S EL K++
Sbjct: 1280 LESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEV 1339
Query: 3074 FDPKNA--KRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLE 3131
F + K+ + +A + + +++ + + AGLE +L++ + + +L+
Sbjct: 1340 FQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQ 1398
Query: 3132 ELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVV 3191
+L++ + VS L + + + K++ E+ + ++ IKA L QL+ + K + ++
Sbjct: 1399 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA---LHTQLEMQAKEHDERIK 1455
Query: 3192 EITEELATLPKRAQ---------------LAAAFITYLSAAPE--------SLRKTCLEE 3228
++ EL + ++ + L AA I+ A E SL + +E
Sbjct: 1456 QLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIER 1515
Query: 3229 WTKS-AGLEK-------------------FDLRRFLCTESEQLIWKSEGLPSDDLSIENA 3268
TKS A +E + R L TE ++ + +++ L S S++ A
Sbjct: 1516 LTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLA 1575
Query: 3269 LVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLK-DSRLEVINQQDSNFITALEL---- 3323
L L K + +++TEW + H + E++ Q N E
Sbjct: 1576 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHV 1635
Query: 3324 --AVRFGKTLIIQEMDGVEPVLYPLLRR---------DLVAQGPRYVVQIGDKIIDYNEE 3372
AVR K + ++ E ++ ++ + ++ KI++ EE
Sbjct: 1636 VEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEE 1695
Query: 3373 FRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQ 3432
+ +P + + N + R ++ T+ + L +K L ++
Sbjct: 1696 NDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEE 1755
Query: 3433 EEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISL 3492
+D K Q +E + Q N+ + N T+ + I +E L +S
Sbjct: 1756 VQDLKHQ--------IEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMST 1807
Query: 3493 DQERDAYLPLAESA----SKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTE 3548
+P A+SA SK + +++ L + +NK+ S+ E
Sbjct: 1808 RPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1867
Query: 3549 QRIQSLISSL 3558
+L+S +
Sbjct: 1868 NEKNTLLSQI 1877
Score = 39.3 bits (90), Expect = 0.086
Identities = 98/464 (21%), Positives = 177/464 (38%), Gaps = 99/464 (21%)
Query: 2813 NSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRY 2872
+ S K+IP SET GE DK+ KE +K + C+
Sbjct: 1021 DESKKEIP---LSETERGEVEEDKENKEYSEK------------CVTSKCQE-------- 1057
Query: 2873 MTFLHVY-SAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGE---QSVLLKTK 2928
+ +Y S K+ EL + L+ ++ + +ALV ++N+ + Q LL+ +
Sbjct: 1058 ---IEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAE 1114
Query: 2929 QDEADAALQMITVSMQDASEQKT----------------ELERLKHRIAEEVVKIEERKN 2972
E A +Q + S DAS+ + E K + E+++ +E+ K
Sbjct: 1115 ISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKE 1174
Query: 2973 KIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWV 3032
++ +L+ EA + I ++ + R LR + ++ + RL FD
Sbjct: 1175 QLQKKLQ-------EALTSRKAILKKAQEKERHLR---EELKQQKDDYNRLQEQFD---- 1220
Query: 3033 SMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAW 3092
++ + R + ++RES++ L P ++ S ++ P
Sbjct: 1221 -------EQSKENENIGDQLRQLQIQVRESIDGKL--------PSTDQQESCSSTP---- 1261
Query: 3093 VKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRT 3152
L + Q LESNL + L G V+++K + +
Sbjct: 1262 -----GLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQG-GTSVAQIKAQLKEIE 1315
Query: 3153 SEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFIT 3212
+E +LE +VS + + QL ++ N Q +EI E L T+ A++ A
Sbjct: 1316 AEKVELELKVSSTTSELTKKSEEVFQL---QEQINKQGLEI-ESLKTVSHEAEVHA---- 1367
Query: 3213 YLSAAPESLRKTCLEEWTKSAGLEKFDLRRFLCTESEQLIWKSE 3256
ESL++ + AGLE + E ++LI K E
Sbjct: 1368 ------ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKE 1405
Score = 36.2 bits (82), Expect = 0.72
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 3416 QHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASS 3475
+H KP+LEE K+L E++K+ KL+E+L A + + + L E L Q K
Sbjct: 1156 EHWKPELEE---KILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDY 1212
Query: 3476 ALIQESLKESYKLQISL-DQERDAYLPLAES 3505
+QE E K ++ DQ R + + ES
Sbjct: 1213 NRLQEQFDEQSKENENIGDQLRQLQIQVRES 1243
Score = 35.4 bits (80), Expect = 1.2
Identities = 68/341 (19%), Positives = 143/341 (41%), Gaps = 37/341 (10%)
Query: 2879 YSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDEL----NRKAGEQSVLLKTKQDEADA 2934
+S SK++E+ ++ + +L + ++EL +R ++ + Q E
Sbjct: 2215 FSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQL 2274
Query: 2935 ALQMITVSMQDASEQKTELER---LKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLA 2991
++ + E ++LE L H E+ K+E + D+L ++ + + K
Sbjct: 2275 QQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ 2334
Query: 2992 VGNIK---PESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMK-----SFLAKRGV 3043
GN++ + ++I++ + + + L+ L ++MK S L+ +
Sbjct: 2335 KGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEE-INMKEQKIISLLSGKEE 2393
Query: 3044 REDIATFDAR-NISKEIRESVEELLFKNKGS---FDPKNAK---RASTAAAPLAAWVKAN 3096
+A + R KEI+E +E LL + + + +N K + + L K N
Sbjct: 2394 AIQVAIAELRQQHDKEIKE-LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEN 2452
Query: 3097 IQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAA 3156
IQ L+ ++S DR R + + + +S + EK Q EAA
Sbjct: 2453 IQQKAQLDSF---------VKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQ-LIQEAA 2502
Query: 3157 KLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEEL 3197
AE +K +E I+ ++ L+ E+ + +A++++ E+L
Sbjct: 2503 ---AENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDL 2540
Score = 33.9 bits (76), Expect = 3.6
Identities = 81/387 (20%), Positives = 156/387 (40%), Gaps = 72/387 (18%)
Query: 2880 SAISSSKKKELLKRQSHLQAGVSKLNEAKALVD-EL--NRKAGEQSVLLKTKQDEADAAL 2936
+A ++ K+E+ +SH+ LN A +D EL R+ Q + +K Q +
Sbjct: 2502 AAENNKLKEEIRGLRSHMD----DLNSENAKLDAELIQYREDLNQVITIKDSQQK----- 2552
Query: 2937 QMITVSMQDASEQKTELERLKHRIAEEVVKIEERK---NKIDDELKEVQPLVNEAKLAVG 2993
Q++ V +Q E + + +L+ ++ E E+ + N + +E +++ + K+++
Sbjct: 2553 QLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSIS 2612
Query: 2994 NIKPE--SLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFD 3051
+ + +L E +L + ++ E V RL +F +S
Sbjct: 2613 QLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSS--------------------- 2651
Query: 3052 ARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLET 3111
K I E EEL+ K A+ + +K +++ H I ET
Sbjct: 2652 ----QKRIAELEEELVCVQK---------EAAKKVGEIEDKLKKELKHLHHDAGIMRNET 2698
Query: 3112 EQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKA 3171
E E+R +L L + QK+ + ++ + T++ +S Q +
Sbjct: 2699 E---------TAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDH 2749
Query: 3172 AEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTK 3231
A +LD ++++A + +ELA L ++ L LS S+ T E
Sbjct: 2750 AN---EELDELKRKYDASL----KELAQLKEQGLLNRERDALLSETAFSMNST---EENS 2799
Query: 3232 SAGLEKFDLRRFLCTESEQLIWKSEGL 3258
+ LEK L + L ++ EQL+ S L
Sbjct: 2800 LSHLEK--LNQQLLSKDEQLLHLSSQL 2824
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 56.2 bits (134), Expect = 7e-07
Identities = 95/474 (20%), Positives = 186/474 (39%), Gaps = 47/474 (9%)
Query: 2814 SSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYM 2873
+ +K++ E L E + KKRK E + + + D L + + K AT ++
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 2874 TFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEAD 2933
+ + K ++++ +A L++ +A D++N + V L+ + D+ +
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLT-KAKVKLEQQVDDLE 1035
Query: 2934 AALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVN------E 2987
+L+ D K +LE E ++ +E K ++D+ LK+ +N E
Sbjct: 1036 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Query: 2988 AKLAVGNIKPESLSEIRS----LRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGV 3043
+ A+G+ + L E+++ L + R V +L + L + G
Sbjct: 1096 DEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG- 1154
Query: 3044 REDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVL 3103
A ++ E+ + E K + + + +TAAA + + +
Sbjct: 1155 -------GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1207
Query: 3104 ERIH----PLETEQAGLE-------SNLKKTEDRK-------RKLEELLNSVGQKVSELK 3145
+ + LE E++ + SN+++ K R LE+ +N K E +
Sbjct: 1208 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQ 1267
Query: 3146 EKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQ 3205
TS+ AKL+ E + + E LI+QL R + Q+ ++ +L K
Sbjct: 1268 RSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKN 1327
Query: 3206 LAAAFITYLSAAPESLRKTC--LEEWTKSAGLEKFDLRRFLC-TESEQLIWKSE 3256
L+ A +S R C L E + K +L+R L SE W+++
Sbjct: 1328 A-------LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374
Score = 46.6 bits (109), Expect = 5e-04
Identities = 56/279 (20%), Positives = 120/279 (43%), Gaps = 17/279 (6%)
Query: 2889 ELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASE 2948
+L+K + L+A V ++NE +E+N + + L+ + E + + +++ +
Sbjct: 907 QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 2949 QKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRM 3008
+K E + EE+ ++E K+ E K +Q +A L + + ++ + ++
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA-LDDLQAEEDKVNTLTKAKV 1025
Query: 3009 PPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLF 3068
+ D LEG L V M AKR + D+ K +ES+ + L
Sbjct: 1026 KLEQQVDDLEGSLE-----QEKKVRMDLERAKRKLEGDL---------KLTQESIMD-LE 1070
Query: 3069 KNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKR 3128
+K D + K+ A A S + +++ L+ LE L+ +
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 3129 KLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQE 3167
K+E+L + + +++ E+ E+ + A ++ E++K +E
Sbjct: 1131 KVEKLRSDLSRELEEISERLE-EAGGATSVQIEMNKKRE 1168
Score = 45.4 bits (106), Expect = 0.001
Identities = 57/305 (18%), Positives = 122/305 (40%), Gaps = 26/305 (8%)
Query: 2882 ISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAG---EQSVLLKTKQDEADAALQM 2938
+++ +K++ QS L+ +L++A D+L ++ LL+ + +E A ++
Sbjct: 1635 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 2939 ITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPE 2998
S + A ++ E + + + +K K+D +L ++Q V EA N + +
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 2999 SLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARN---- 3054
+ I M + ++ + L + ++K + E IA +
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQK 1814
Query: 3055 ISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQA 3114
+ +RE EL + K + + R S RI L +
Sbjct: 1815 LEARVRELENELEAEQKRNAESVKGMRKSE-------------------RRIKELTYQTE 1855
Query: 3115 GLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEV 3174
NL + +D KL+ + + ++ E +E+ + S+ K++ E+ +A+E AE
Sbjct: 1856 EDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAES 1915
Query: 3175 LINQL 3179
+N+L
Sbjct: 1916 QVNKL 1920
Score = 43.5 bits (101), Expect = 0.005
Identities = 65/350 (18%), Positives = 142/350 (40%), Gaps = 37/350 (10%)
Query: 2886 KKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQD 2945
+K E + + + ++ +AKA ++++ R +Q ++K +E ++ +T
Sbjct: 1220 EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 2946 ASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRS 3005
+ EL R + ++ K +L++++ + E A K ++S
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKA----KNALAHALQS 1335
Query: 3006 LRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEE 3065
R D++R+ E S +A+ + + DA ++E+ E+ ++
Sbjct: 1336 ARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYET---DAIQRTEELEEAKKK 1392
Query: 3066 LLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKT-- 3123
L A+R A + A N + S + + H L+ E L +++++
Sbjct: 1393 L------------AQRLQEAEEAVEA---VNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1437
Query: 3124 -----EDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQ 3178
+ ++R +++L QK E + + +S EA L E+ K + + + +
Sbjct: 1438 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Query: 3179 LDREHKRWNAQVVEITEELATLPK--------RAQLAAAFITYLSAAPES 3220
RE+K ++ ++TE+L + K R QL A + SA E+
Sbjct: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEA 1547
Score = 42.4 bits (98), Expect = 0.010
Identities = 84/385 (21%), Positives = 157/385 (40%), Gaps = 46/385 (11%)
Query: 2883 SSSKKKELLKRQ-SHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITV 2941
S K K L+ + L V + N A A +D+ R + K K +E+ + L+
Sbjct: 1413 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES--- 1469
Query: 2942 SMQDASEQKTELERLKHRIAEEVVKIE--ERKNK--------IDDELKEVQPLVNEAKLA 2991
S ++A TEL +LK+ E + +E +R+NK + ++L ++E +
Sbjct: 1470 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV 1529
Query: 2992 VGNIKPESLSEIRSLRMPPDVIRDILEG-VLRLMGIFDTSWVSMKSFLAKR------GVR 3044
++ E + E++S + + EG +LR F+ ++ LA++ R
Sbjct: 1530 RKQLEAEKM-ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 3045 EDIATFDA--RNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHV 3102
+ D+ ++ E R E L K K D + + A +AA + ++
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Query: 3103 LERIHPLETEQAGLESNLKKTEDRKRKL---EELLNSVGQKVSELKEKFQSRTSEAAKLE 3159
L L+ Q L+ ++ +D K + E N + ++ EL+ + E
Sbjct: 1649 L-----LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 3160 AEVSKAQETIKAAE----VLINQ---LDREHKRWNAQVVEITEELATLPKRAQLAAAFIT 3212
E+ + E ++ LINQ +D + + +V E +E ++A+ A IT
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA---IT 1760
Query: 3213 YLSAAPESLRKTCLEEWTKSAGLEK 3237
+ E L+K E SA LE+
Sbjct: 1761 DAAMMAEELKK----EQDTSAHLER 1781
Score = 38.1 bits (87), Expect = 0.19
Identities = 66/332 (19%), Positives = 149/332 (44%), Gaps = 29/332 (8%)
Query: 2889 ELLKRQS-HLQAGVSKLNE-----AKAL--VDELNRKAGEQSVLLKTKQDEADAALQ--- 2937
E KR++ +LQ +S L E K + ++++ ++ + + L++ +EA+A+L+
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 2938 -MITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK 2996
I + + ++ K E+ER ++AE+ ++E+ K + L+ V L ++
Sbjct: 1556 GKILRAQLEFNQIKAEIER---KLAEKDEEMEQAKR---NHLRVVDSLQT-------SLD 1602
Query: 2997 PESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVRED--IATFDARN 3054
E+ S +LR+ + D+ E ++L + + K + + + +D I DA
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR 1662
Query: 3055 ISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQA 3114
+ +++E++ + +N RA + + A + ER+ L ++
Sbjct: 1663 ANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL-AEQELIETSERVQLLHSQNT 1721
Query: 3115 GLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEV 3174
L + KK + +L+ + Q+ +EK + ++AA + E+ K Q+T E
Sbjct: 1722 SLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1781
Query: 3175 LINQLDREHKRWNAQVVEITEELATLPKRAQL 3206
+ +++ K ++ E E++A + QL
Sbjct: 1782 MKKNMEQTIKDLQHRLDE-AEQIALKGGKKQL 1812
Score = 37.4 bits (85), Expect = 0.33
Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 3102 VLERIHPLETEQAGLESNLKKTEDR-------KRKLEELLNSVGQKVSELKEKFQSRTSE 3154
+L+ + L+ + + NL E+R K +LE + + +++ + +E T++
Sbjct: 880 LLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAK 939
Query: 3155 AAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATL 3200
KLE E S+ + I E+ + ++++E +V +TEE+A L
Sbjct: 940 KRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Score = 35.4 bits (80), Expect = 1.2
Identities = 38/172 (22%), Positives = 80/172 (46%), Gaps = 24/172 (13%)
Query: 3109 LETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAA------------ 3156
++ E L+ L+K+E R+++LEE + S+ Q+ ++L+ + Q+ A
Sbjct: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 3157 --KLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYL 3214
+LEA+V + E ++ E + +L + ++ + E+ ++ L +L A +
Sbjct: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDL----ELTLAKVEKE 967
Query: 3215 SAAPESLRKTCLEEWTKSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIE 3266
A E+ K EE AGL++ + T+ ++ + ++ DDL E
Sbjct: 968 KHATENKVKNLTEE---MAGLDEIIAK---LTKEKKALQEAHQQALDDLQAE 1013
Score = 35.4 bits (80), Expect = 1.2
Identities = 114/585 (19%), Positives = 225/585 (38%), Gaps = 87/585 (14%)
Query: 966 IGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESH 1025
I D S+LQ++ E+ +E E++ LE +AK +K +
Sbjct: 1094 IEDEQALGSQLQKKLKELQARIEELEEE-----------LEAERTARAKVEKLRSDLSRE 1142
Query: 1026 QLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKE 1085
I +++E G ++++ + +F+ L+ E K A + E
Sbjct: 1143 LEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1202
Query: 1086 KKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMA 1145
+ D+L+ ++KL + F+LE ++ ++E + A E+ + ++
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLE------LDDVTSNMEQIIKAKANLEKMCRTLEDQM 1256
Query: 1146 NEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHL 1205
NE R+K EE + +D + + +L ++D+ + +I L RG+
Sbjct: 1257 NE----HRSKA---EETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL--TRGKLT 1307
Query: 1206 SPDHWLDLFRLL--GLPRGTSLEKLLFG-----DLLRVADTIVAKA-ADLKDLNSRAQGE 1257
DL R L + +L L DLLR +A A+L+ + S+A E
Sbjct: 1308 YTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1367
Query: 1258 VTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPY 1317
V E D A+ + E+++ + + +++ ++ V V L+ K
Sbjct: 1368 VAQWRTKYETD-----AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHR-L 1421
Query: 1318 YKGFEDKVSIWERK---LAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDED 1374
ED + ER A LD+ +N + I +W + + Q+ ++
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW--------KQKYEESQSELESSQKE 1473
Query: 1375 FRSIMTDI-----------------KKDNR-----VTTLTTHAGIRNSLLTILDQLQRCQ 1412
RS+ T++ K++N+ ++ LT G S + +L++ +
Sbjct: 1474 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG---SSGKTIHELEKVR 1530
Query: 1413 KSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKH 1472
K L E +SA + + +IL + I++ +++ A + K H
Sbjct: 1531 KQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH 1590
Query: 1473 ITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKE 1517
+ + SL+ S + ET + AL +KK +E L E
Sbjct: 1591 LRVVDSLQ-----------TSLDAETRSRNEALRVKKKMEGDLNE 1624
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 56.2 bits (134), Expect = 7e-07
Identities = 62/307 (20%), Positives = 137/307 (44%), Gaps = 28/307 (9%)
Query: 2901 VSKLNEAKALVDELNRKAGEQSVLLKTK---------QDEADAALQMITVSMQDASEQKT 2951
+ +N+ KA + E ++A E+ + LK DEA+ + + + + ++Q +
Sbjct: 590 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVS 649
Query: 2952 ELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK----PESLSEIRSLR 3007
EL +L E+ +RK+ D + + +E + + N+ ++LSE++S
Sbjct: 650 ELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKS-- 707
Query: 3008 MPPDVIRDILEGVLRLMGIFDTSWVSMKSFL--------AKRGVREDIATFDARNISKEI 3059
V+ ++ + + +L+ + VS+ L A + + E I+ SKE+
Sbjct: 708 QYSKVLNELTQ-LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEV 766
Query: 3060 RES-VEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLE---TEQAG 3115
+ +E+ L + K + R+S + + ++ S + E + E +E
Sbjct: 767 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 826
Query: 3116 LESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVL 3175
+ S + + + K ++ LL S Q+V+EL +KFQ E A+++ + + + +
Sbjct: 827 IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKK 886
Query: 3176 INQLDRE 3182
IN++ +E
Sbjct: 887 INEMSKE 893
Score = 40.8 bits (94), Expect = 0.029
Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 14/127 (11%)
Query: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
++ +SK KE +K + + + V ++ ++ V ++ R+ LLK+K+ E + LQ
Sbjct: 804 SVLASKLKESVKEKEKVHSEVVQI---RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQ 860
Query: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
+ ++ +E K R AE K+EE K+K ++ E+ V + K A+ ++ S
Sbjct: 861 QAQEELAEMK--------RYAESSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQLSY 909
Query: 3001 SEIRSLR 3007
S S R
Sbjct: 910 STSSSKR 916
Score = 37.0 bits (84), Expect = 0.42
Identities = 101/489 (20%), Positives = 192/489 (39%), Gaps = 62/489 (12%)
Query: 659 GKSQITWDNP---KELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNID----- 710
GKS T DN ++L+ +Q LQ E E ++L+ + ++V L N +
Sbjct: 424 GKS--TTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENS 481
Query: 711 ------LLRQQQRWKDGLQE-------LRTGLATVEAQGFQASDMHAWKQHWNHQLYKAL 757
L Q ++++ ++E ++ GL + E+ + H + + L
Sbjct: 482 SDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS---HFHELRVTEEEINVL 538
Query: 758 EHQYQMGLEALNEN---LPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG--IPNQ 812
+ Q LE N + E+ L ++ +PP EE Y EMK I N
Sbjct: 539 KQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEE-----YEEMKSSYCSVIENM 593
Query: 813 FKGVG------EAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQ-HKEWIVIGQ 865
K + E I + + +AED+ ++ ++ + +K+ + Q
Sbjct: 594 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 653
Query: 866 VDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKV------DCLNINCNPVKTVI 919
+ EA E + ++ A I E E+L V D L+ + V+
Sbjct: 654 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 713
Query: 920 DDLIQKLFDLLVLSLKK---SIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKL 976
++L Q LV + K+ SI HL I T T A E+ + E + ++ +KL
Sbjct: 714 NELTQ--LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKL 771
Query: 977 QERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWD---KFELMMESHQLMIK--- 1030
+++ E +A + +S L +K K + + S + I+
Sbjct: 772 EKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEV 831
Query: 1031 DQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEF 1090
Q++ K N+++ L+ QE+ + ++ Q + +++ E ++ + K+KKI
Sbjct: 832 SQVKREKENIQTLLKSKEQEVNELLQKFQQAQ--EELAEMKRYAESSSKLEEDKDKKINE 889
Query: 1091 DDLEVTRKK 1099
EVT+ K
Sbjct: 890 MSKEVTKLK 898
Score = 34.7 bits (78), Expect = 2.1
Identities = 54/232 (23%), Positives = 97/232 (41%), Gaps = 67/232 (28%)
Query: 3414 TIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKA 3473
T++ ++EE+ + L + K++++AKLE+ LLE A
Sbjct: 742 TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA-------------------M 782
Query: 3474 SSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRL 3533
+ A++ S E KLQ SL+ E ++ ASK+ + + K++ + +++
Sbjct: 783 TDAMVPRSSYE--KLQSSLESE------VSVLASKLKESVKEKEKVH-------SEVVQI 827
Query: 3534 FQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQE 3593
Q K++ EN IQ+L+ S + V E + + FQ+
Sbjct: 828 RSEVSQVKREKEN----IQTLLKSKEQEVNELL----------------------QKFQQ 861
Query: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQ 3645
+ + + +M R A+S K+ + I+ E S V LK AL SL Q
Sbjct: 862 AQEE------LAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSLSQ 906
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 56.2 bits (134), Expect = 7e-07
Identities = 62/307 (20%), Positives = 137/307 (44%), Gaps = 28/307 (9%)
Query: 2901 VSKLNEAKALVDELNRKAGEQSVLLKTK---------QDEADAALQMITVSMQDASEQKT 2951
+ +N+ KA + E ++A E+ + LK DEA+ + + + + ++Q +
Sbjct: 579 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVS 638
Query: 2952 ELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK----PESLSEIRSLR 3007
EL +L E+ +RK+ D + + +E + + N+ ++LSE++S
Sbjct: 639 ELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKS-- 696
Query: 3008 MPPDVIRDILEGVLRLMGIFDTSWVSMKSFL--------AKRGVREDIATFDARNISKEI 3059
V+ ++ + + +L+ + VS+ L A + + E I+ SKE+
Sbjct: 697 QYSKVLNELTQ-LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEV 755
Query: 3060 RES-VEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLE---TEQAG 3115
+ +E+ L + K + R+S + + ++ S + E + E +E
Sbjct: 756 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 815
Query: 3116 LESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVL 3175
+ S + + + K ++ LL S Q+V+EL +KFQ E A+++ + + + +
Sbjct: 816 IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKK 875
Query: 3176 INQLDRE 3182
IN++ +E
Sbjct: 876 INEMSKE 882
Score = 40.8 bits (94), Expect = 0.029
Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 14/127 (11%)
Query: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
++ +SK KE +K + + + V ++ ++ V ++ R+ LLK+K+ E + LQ
Sbjct: 793 SVLASKLKESVKEKEKVHSEVVQI---RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQ 849
Query: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
+ ++ +E K R AE K+EE K+K ++ E+ V + K A+ ++ S
Sbjct: 850 QAQEELAEMK--------RYAESSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQLSY 898
Query: 3001 SEIRSLR 3007
S S R
Sbjct: 899 STSSSKR 905
Score = 37.0 bits (84), Expect = 0.42
Identities = 101/489 (20%), Positives = 192/489 (39%), Gaps = 62/489 (12%)
Query: 659 GKSQITWDNP---KELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNID----- 710
GKS T DN ++L+ +Q LQ E E ++L+ + ++V L N +
Sbjct: 413 GKS--TTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENS 470
Query: 711 ------LLRQQQRWKDGLQE-------LRTGLATVEAQGFQASDMHAWKQHWNHQLYKAL 757
L Q ++++ ++E ++ GL + E+ + H + + L
Sbjct: 471 SDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS---HFHELRVTEEEINVL 527
Query: 758 EHQYQMGLEALNEN---LPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG--IPNQ 812
+ Q LE N + E+ L ++ +PP EE Y EMK I N
Sbjct: 528 KQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEE-----YEEMKSSYCSVIENM 582
Query: 813 FKGVG------EAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQ-HKEWIVIGQ 865
K + E I + + +AED+ ++ ++ + +K+ + Q
Sbjct: 583 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 642
Query: 866 VDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKV------DCLNINCNPVKTVI 919
+ EA E + ++ A I E E+L V D L+ + V+
Sbjct: 643 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 702
Query: 920 DDLIQKLFDLLVLSLKK---SIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKL 976
++L Q LV + K+ SI HL I T T A E+ + E + ++ +KL
Sbjct: 703 NELTQ--LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKL 760
Query: 977 QERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWD---KFELMMESHQLMIK--- 1030
+++ E +A + +S L +K K + + S + I+
Sbjct: 761 EKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEV 820
Query: 1031 DQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEF 1090
Q++ K N+++ L+ QE+ + ++ Q + +++ E ++ + K+KKI
Sbjct: 821 SQVKREKENIQTLLKSKEQEVNELLQKFQQAQ--EELAEMKRYAESSSKLEEDKDKKINE 878
Query: 1091 DDLEVTRKK 1099
EVT+ K
Sbjct: 879 MSKEVTKLK 887
Score = 34.7 bits (78), Expect = 2.1
Identities = 54/232 (23%), Positives = 97/232 (41%), Gaps = 67/232 (28%)
Query: 3414 TIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKA 3473
T++ ++EE+ + L + K++++AKLE+ LLE A
Sbjct: 731 TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA-------------------M 771
Query: 3474 SSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRL 3533
+ A++ S E KLQ SL+ E ++ ASK+ + + K++ + +++
Sbjct: 772 TDAMVPRSSYE--KLQSSLESE------VSVLASKLKESVKEKEKVH-------SEVVQI 816
Query: 3534 FQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQE 3593
Q K++ EN IQ+L+ S + V E + + FQ+
Sbjct: 817 RSEVSQVKREKEN----IQTLLKSKEQEVNELL----------------------QKFQQ 850
Query: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQ 3645
+ + + +M R A+S K+ + I+ E S V LK AL SL Q
Sbjct: 851 AQEE------LAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSLSQ 895
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 56.2 bits (134), Expect = 7e-07
Identities = 62/307 (20%), Positives = 137/307 (44%), Gaps = 28/307 (9%)
Query: 2901 VSKLNEAKALVDELNRKAGEQSVLLKTK---------QDEADAALQMITVSMQDASEQKT 2951
+ +N+ KA + E ++A E+ + LK DEA+ + + + + ++Q +
Sbjct: 558 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVS 617
Query: 2952 ELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK----PESLSEIRSLR 3007
EL +L E+ +RK+ D + + +E + + N+ ++LSE++S
Sbjct: 618 ELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKS-- 675
Query: 3008 MPPDVIRDILEGVLRLMGIFDTSWVSMKSFL--------AKRGVREDIATFDARNISKEI 3059
V+ ++ + + +L+ + VS+ L A + + E I+ SKE+
Sbjct: 676 QYSKVLNELTQ-LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEV 734
Query: 3060 RES-VEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLE---TEQAG 3115
+ +E+ L + K + R+S + + ++ S + E + E +E
Sbjct: 735 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 794
Query: 3116 LESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVL 3175
+ S + + + K ++ LL S Q+V+EL +KFQ E A+++ + + + +
Sbjct: 795 IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKK 854
Query: 3176 INQLDRE 3182
IN++ +E
Sbjct: 855 INEMSKE 861
Score = 40.8 bits (94), Expect = 0.029
Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 14/127 (11%)
Query: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
++ +SK KE +K + + + V ++ ++ V ++ R+ LLK+K+ E + LQ
Sbjct: 772 SVLASKLKESVKEKEKVHSEVVQI---RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQ 828
Query: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
+ ++ +E K R AE K+EE K+K ++ E+ V + K A+ ++ S
Sbjct: 829 QAQEELAEMK--------RYAESSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQLSY 877
Query: 3001 SEIRSLR 3007
S S R
Sbjct: 878 STSSSKR 884
Score = 37.0 bits (84), Expect = 0.42
Identities = 101/489 (20%), Positives = 192/489 (39%), Gaps = 62/489 (12%)
Query: 659 GKSQITWDNP---KELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNID----- 710
GKS T DN ++L+ +Q LQ E E ++L+ + ++V L N +
Sbjct: 392 GKS--TTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENS 449
Query: 711 ------LLRQQQRWKDGLQE-------LRTGLATVEAQGFQASDMHAWKQHWNHQLYKAL 757
L Q ++++ ++E ++ GL + E+ + H + + L
Sbjct: 450 SDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS---HFHELRVTEEEINVL 506
Query: 758 EHQYQMGLEALNEN---LPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG--IPNQ 812
+ Q LE N + E+ L ++ +PP EE Y EMK I N
Sbjct: 507 KQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEE-----YEEMKSSYCSVIENM 561
Query: 813 FKGVG------EAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQ-HKEWIVIGQ 865
K + E I + + +AED+ ++ ++ + +K+ + Q
Sbjct: 562 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 621
Query: 866 VDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKV------DCLNINCNPVKTVI 919
+ EA E + ++ A I E E+L V D L+ + V+
Sbjct: 622 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 681
Query: 920 DDLIQKLFDLLVLSLKK---SIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKL 976
++L Q LV + K+ SI HL I T T A E+ + E + ++ +KL
Sbjct: 682 NELTQ--LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKL 739
Query: 977 QERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWD---KFELMMESHQLMIK--- 1030
+++ E +A + +S L +K K + + S + I+
Sbjct: 740 EKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEV 799
Query: 1031 DQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEF 1090
Q++ K N+++ L+ QE+ + ++ Q + +++ E ++ + K+KKI
Sbjct: 800 SQVKREKENIQTLLKSKEQEVNELLQKFQQAQ--EELAEMKRYAESSSKLEEDKDKKINE 857
Query: 1091 DDLEVTRKK 1099
EVT+ K
Sbjct: 858 MSKEVTKLK 866
Score = 34.7 bits (78), Expect = 2.1
Identities = 54/232 (23%), Positives = 97/232 (41%), Gaps = 67/232 (28%)
Query: 3414 TIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKA 3473
T++ ++EE+ + L + K++++AKLE+ LLE A
Sbjct: 710 TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA-------------------M 750
Query: 3474 SSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRL 3533
+ A++ S E KLQ SL+ E ++ ASK+ + + K++ + +++
Sbjct: 751 TDAMVPRSSYE--KLQSSLESE------VSVLASKLKESVKEKEKVH-------SEVVQI 795
Query: 3534 FQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQE 3593
Q K++ EN IQ+L+ S + V E + + FQ+
Sbjct: 796 RSEVSQVKREKEN----IQTLLKSKEQEVNELL----------------------QKFQQ 829
Query: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQ 3645
+ + + +M R A+S K+ + I+ E S V LK AL SL Q
Sbjct: 830 AQEE------LAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSLSQ 874
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 56.2 bits (134), Expect = 7e-07
Identities = 62/307 (20%), Positives = 137/307 (44%), Gaps = 28/307 (9%)
Query: 2901 VSKLNEAKALVDELNRKAGEQSVLLKTK---------QDEADAALQMITVSMQDASEQKT 2951
+ +N+ KA + E ++A E+ + LK DEA+ + + + + ++Q +
Sbjct: 587 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVS 646
Query: 2952 ELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK----PESLSEIRSLR 3007
EL +L E+ +RK+ D + + +E + + N+ ++LSE++S
Sbjct: 647 ELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKS-- 704
Query: 3008 MPPDVIRDILEGVLRLMGIFDTSWVSMKSFL--------AKRGVREDIATFDARNISKEI 3059
V+ ++ + + +L+ + VS+ L A + + E I+ SKE+
Sbjct: 705 QYSKVLNELTQ-LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEV 763
Query: 3060 RES-VEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLE---TEQAG 3115
+ +E+ L + K + R+S + + ++ S + E + E +E
Sbjct: 764 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 823
Query: 3116 LESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVL 3175
+ S + + + K ++ LL S Q+V+EL +KFQ E A+++ + + + +
Sbjct: 824 IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKK 883
Query: 3176 INQLDRE 3182
IN++ +E
Sbjct: 884 INEMSKE 890
Score = 40.8 bits (94), Expect = 0.029
Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 14/127 (11%)
Query: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
++ +SK KE +K + + + V ++ ++ V ++ R+ LLK+K+ E + LQ
Sbjct: 801 SVLASKLKESVKEKEKVHSEVVQI---RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQ 857
Query: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
+ ++ +E K R AE K+EE K+K ++ E+ V + K A+ ++ S
Sbjct: 858 QAQEELAEMK--------RYAESSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQLSY 906
Query: 3001 SEIRSLR 3007
S S R
Sbjct: 907 STSSSKR 913
Score = 37.0 bits (84), Expect = 0.42
Identities = 101/489 (20%), Positives = 192/489 (39%), Gaps = 62/489 (12%)
Query: 659 GKSQITWDNP---KELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNID----- 710
GKS T DN ++L+ +Q LQ E E ++L+ + ++V L N +
Sbjct: 421 GKS--TTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENS 478
Query: 711 ------LLRQQQRWKDGLQE-------LRTGLATVEAQGFQASDMHAWKQHWNHQLYKAL 757
L Q ++++ ++E ++ GL + E+ + H + + L
Sbjct: 479 SDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS---HFHELRVTEEEINVL 535
Query: 758 EHQYQMGLEALNEN---LPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG--IPNQ 812
+ Q LE N + E+ L ++ +PP EE Y EMK I N
Sbjct: 536 KQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEE-----YEEMKSSYCSVIENM 590
Query: 813 FKGVG------EAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQ-HKEWIVIGQ 865
K + E I + + +AED+ ++ ++ + +K+ + Q
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 650
Query: 866 VDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKV------DCLNINCNPVKTVI 919
+ EA E + ++ A I E E+L V D L+ + V+
Sbjct: 651 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 920 DDLIQKLFDLLVLSLKK---SIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKL 976
++L Q LV + K+ SI HL I T T A E+ + E + ++ +KL
Sbjct: 711 NELTQ--LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKL 768
Query: 977 QERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWD---KFELMMESHQLMIK--- 1030
+++ E +A + +S L +K K + + S + I+
Sbjct: 769 EKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEV 828
Query: 1031 DQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEF 1090
Q++ K N+++ L+ QE+ + ++ Q + +++ E ++ + K+KKI
Sbjct: 829 SQVKREKENIQTLLKSKEQEVNELLQKFQQAQ--EELAEMKRYAESSSKLEEDKDKKINE 886
Query: 1091 DDLEVTRKK 1099
EVT+ K
Sbjct: 887 MSKEVTKLK 895
Score = 34.7 bits (78), Expect = 2.1
Identities = 54/232 (23%), Positives = 97/232 (41%), Gaps = 67/232 (28%)
Query: 3414 TIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKA 3473
T++ ++EE+ + L + K++++AKLE+ LLE A
Sbjct: 739 TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA-------------------M 779
Query: 3474 SSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRL 3533
+ A++ S E KLQ SL+ E ++ ASK+ + + K++ + +++
Sbjct: 780 TDAMVPRSSYE--KLQSSLESE------VSVLASKLKESVKEKEKVH-------SEVVQI 824
Query: 3534 FQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQE 3593
Q K++ EN IQ+L+ S + V E + + FQ+
Sbjct: 825 RSEVSQVKREKEN----IQTLLKSKEQEVNELL----------------------QKFQQ 858
Query: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQ 3645
+ + + +M R A+S K+ + I+ E S V LK AL SL Q
Sbjct: 859 AQEE------LAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSLSQ 903
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 56.2 bits (134), Expect = 7e-07
Identities = 62/307 (20%), Positives = 137/307 (44%), Gaps = 28/307 (9%)
Query: 2901 VSKLNEAKALVDELNRKAGEQSVLLKTK---------QDEADAALQMITVSMQDASEQKT 2951
+ +N+ KA + E ++A E+ + LK DEA+ + + + + ++Q +
Sbjct: 587 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVS 646
Query: 2952 ELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK----PESLSEIRSLR 3007
EL +L E+ +RK+ D + + +E + + N+ ++LSE++S
Sbjct: 647 ELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKS-- 704
Query: 3008 MPPDVIRDILEGVLRLMGIFDTSWVSMKSFL--------AKRGVREDIATFDARNISKEI 3059
V+ ++ + + +L+ + VS+ L A + + E I+ SKE+
Sbjct: 705 QYSKVLNELTQ-LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEV 763
Query: 3060 RES-VEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLE---TEQAG 3115
+ +E+ L + K + R+S + + ++ S + E + E +E
Sbjct: 764 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 823
Query: 3116 LESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVL 3175
+ S + + + K ++ LL S Q+V+EL +KFQ E A+++ + + + +
Sbjct: 824 IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKK 883
Query: 3176 INQLDRE 3182
IN++ +E
Sbjct: 884 INEMSKE 890
Score = 40.8 bits (94), Expect = 0.029
Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 14/127 (11%)
Query: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
++ +SK KE +K + + + V ++ ++ V ++ R+ LLK+K+ E + LQ
Sbjct: 801 SVLASKLKESVKEKEKVHSEVVQI---RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQ 857
Query: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
+ ++ +E K R AE K+EE K+K ++ E+ V + K A+ ++ S
Sbjct: 858 QAQEELAEMK--------RYAESSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQLSY 906
Query: 3001 SEIRSLR 3007
S S R
Sbjct: 907 STSSSKR 913
Score = 37.0 bits (84), Expect = 0.42
Identities = 101/489 (20%), Positives = 192/489 (39%), Gaps = 62/489 (12%)
Query: 659 GKSQITWDNP---KELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNID----- 710
GKS T DN ++L+ +Q LQ E E ++L+ + ++V L N +
Sbjct: 421 GKS--TTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENS 478
Query: 711 ------LLRQQQRWKDGLQE-------LRTGLATVEAQGFQASDMHAWKQHWNHQLYKAL 757
L Q ++++ ++E ++ GL + E+ + H + + L
Sbjct: 479 SDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS---HFHELRVTEEEINVL 535
Query: 758 EHQYQMGLEALNEN---LPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG--IPNQ 812
+ Q LE N + E+ L ++ +PP EE Y EMK I N
Sbjct: 536 KQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEE-----YEEMKSSYCSVIENM 590
Query: 813 FKGVG------EAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQ-HKEWIVIGQ 865
K + E I + + +AED+ ++ ++ + +K+ + Q
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 650
Query: 866 VDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKV------DCLNINCNPVKTVI 919
+ EA E + ++ A I E E+L V D L+ + V+
Sbjct: 651 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 920 DDLIQKLFDLLVLSLKK---SIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKL 976
++L Q LV + K+ SI HL I T T A E+ + E + ++ +KL
Sbjct: 711 NELTQ--LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKL 768
Query: 977 QERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWD---KFELMMESHQLMIK--- 1030
+++ E +A + +S L +K K + + S + I+
Sbjct: 769 EKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEV 828
Query: 1031 DQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEF 1090
Q++ K N+++ L+ QE+ + ++ Q + +++ E ++ + K+KKI
Sbjct: 829 SQVKREKENIQTLLKSKEQEVNELLQKFQQAQ--EELAEMKRYAESSSKLEEDKDKKINE 886
Query: 1091 DDLEVTRKK 1099
EVT+ K
Sbjct: 887 MSKEVTKLK 895
Score = 34.7 bits (78), Expect = 2.1
Identities = 54/232 (23%), Positives = 97/232 (41%), Gaps = 67/232 (28%)
Query: 3414 TIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKA 3473
T++ ++EE+ + L + K++++AKLE+ LLE A
Sbjct: 739 TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA-------------------M 779
Query: 3474 SSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRL 3533
+ A++ S E KLQ SL+ E ++ ASK+ + + K++ + +++
Sbjct: 780 TDAMVPRSSYE--KLQSSLESE------VSVLASKLKESVKEKEKVH-------SEVVQI 824
Query: 3534 FQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQE 3593
Q K++ EN IQ+L+ S + V E + + FQ+
Sbjct: 825 RSEVSQVKREKEN----IQTLLKSKEQEVNELL----------------------QKFQQ 858
Query: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQ 3645
+ + + +M R A+S K+ + I+ E S V LK AL SL Q
Sbjct: 859 AQEE------LAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSLSQ 903
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 56.2 bits (134), Expect = 7e-07
Identities = 62/307 (20%), Positives = 137/307 (44%), Gaps = 28/307 (9%)
Query: 2901 VSKLNEAKALVDELNRKAGEQSVLLKTK---------QDEADAALQMITVSMQDASEQKT 2951
+ +N+ KA + E ++A E+ + LK DEA+ + + + + ++Q +
Sbjct: 587 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVS 646
Query: 2952 ELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIK----PESLSEIRSLR 3007
EL +L E+ +RK+ D + + +E + + N+ ++LSE++S
Sbjct: 647 ELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKS-- 704
Query: 3008 MPPDVIRDILEGVLRLMGIFDTSWVSMKSFL--------AKRGVREDIATFDARNISKEI 3059
V+ ++ + + +L+ + VS+ L A + + E I+ SKE+
Sbjct: 705 QYSKVLNELTQ-LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEV 763
Query: 3060 RES-VEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLE---TEQAG 3115
+ +E+ L + K + R+S + + ++ S + E + E +E
Sbjct: 764 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 823
Query: 3116 LESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVL 3175
+ S + + + K ++ LL S Q+V+EL +KFQ E A+++ + + + +
Sbjct: 824 IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKK 883
Query: 3176 INQLDRE 3182
IN++ +E
Sbjct: 884 INEMSKE 890
Score = 40.8 bits (94), Expect = 0.029
Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 14/127 (11%)
Query: 2881 AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT 2940
++ +SK KE +K + + + V ++ ++ V ++ R+ LLK+K+ E + LQ
Sbjct: 801 SVLASKLKESVKEKEKVHSEVVQI---RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQ 857
Query: 2941 VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL 3000
+ ++ +E K R AE K+EE K+K ++ E+ V + K A+ ++ S
Sbjct: 858 QAQEELAEMK--------RYAESSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQLSY 906
Query: 3001 SEIRSLR 3007
S S R
Sbjct: 907 STSSSKR 913
Score = 37.0 bits (84), Expect = 0.42
Identities = 101/489 (20%), Positives = 192/489 (39%), Gaps = 62/489 (12%)
Query: 659 GKSQITWDNP---KELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNID----- 710
GKS T DN ++L+ +Q LQ E E ++L+ + ++V L N +
Sbjct: 421 GKS--TTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENS 478
Query: 711 ------LLRQQQRWKDGLQE-------LRTGLATVEAQGFQASDMHAWKQHWNHQLYKAL 757
L Q ++++ ++E ++ GL + E+ + H + + L
Sbjct: 479 SDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS---HFHELRVTEEEINVL 535
Query: 758 EHQYQMGLEALNEN---LPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG--IPNQ 812
+ Q LE N + E+ L ++ +PP EE Y EMK I N
Sbjct: 536 KQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEE-----YEEMKSSYCSVIENM 590
Query: 813 FKGVG------EAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQ-HKEWIVIGQ 865
K + E I + + +AED+ ++ ++ + +K+ + Q
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 650
Query: 866 VDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKV------DCLNINCNPVKTVI 919
+ EA E + ++ A I E E+L V D L+ + V+
Sbjct: 651 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 920 DDLIQKLFDLLVLSLKK---SIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKL 976
++L Q LV + K+ SI HL I T T A E+ + E + ++ +KL
Sbjct: 711 NELTQ--LKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKL 768
Query: 977 QERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWD---KFELMMESHQLMIK--- 1030
+++ E +A + +S L +K K + + S + I+
Sbjct: 769 EKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEV 828
Query: 1031 DQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEF 1090
Q++ K N+++ L+ QE+ + ++ Q + +++ E ++ + K+KKI
Sbjct: 829 SQVKREKENIQTLLKSKEQEVNELLQKFQQAQ--EELAEMKRYAESSSKLEEDKDKKINE 886
Query: 1091 DDLEVTRKK 1099
EVT+ K
Sbjct: 887 MSKEVTKLK 895
Score = 34.7 bits (78), Expect = 2.1
Identities = 54/232 (23%), Positives = 97/232 (41%), Gaps = 67/232 (28%)
Query: 3414 TIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKA 3473
T++ ++EE+ + L + K++++AKLE+ LLE A
Sbjct: 739 TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA-------------------M 779
Query: 3474 SSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRL 3533
+ A++ S E KLQ SL+ E ++ ASK+ + + K++ + +++
Sbjct: 780 TDAMVPRSSYE--KLQSSLESE------VSVLASKLKESVKEKEKVH-------SEVVQI 824
Query: 3534 FQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQE 3593
Q K++ EN IQ+L+ S + V E + + FQ+
Sbjct: 825 RSEVSQVKREKEN----IQTLLKSKEQEVNELL----------------------QKFQQ 858
Query: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQ 3645
+ + + +M R A+S K+ + I+ E S V LK AL SL Q
Sbjct: 859 AQEE------LAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSLSQ 903
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 55.8 bits (133), Expect = 9e-07
Identities = 144/733 (19%), Positives = 269/733 (36%), Gaps = 97/733 (13%)
Query: 2914 LNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNK 2973
+ ++ GE L + Q++ + T + + + +E+ R + E +IE R K
Sbjct: 967 MEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISR---KYQSEFEEIEGRWKK 1023
Query: 2974 IDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVS 3033
+ +L E + E ++ LR + I+ + + + + W +
Sbjct: 1024 LSSQLVEHCQKLEE--------------QMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPA 1069
Query: 3034 M--KSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAA 3091
+ L K+ + + D + I + SV E K K +P+ A R T L
Sbjct: 1070 LGDSEILKKQLKQCRLLVSDIQTIQPSLN-SVNEGGQKIKNEAEPEFASRLETELKEL-- 1126
Query: 3092 WVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEK-FQS 3150
N Q+ H+ ++++ + L+ L+KT ++ L E+ + Q E E+ F+
Sbjct: 1127 ----NTQWDHMCQQVY---ARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEY 1179
Query: 3151 RT-SEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAA 3209
+T E K E+ +A+E + E + L AQ + +E L K +
Sbjct: 1180 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQE--ALKKELETLTT 1237
Query: 3210 FITYLSAAPESLRKTCLEEWTKSAGLEKF-DLRRFLCTESEQLIWKSEGLPSDDLSIENA 3268
+L KT E W L + + E E + +E +P I
Sbjct: 1238 NYQWLCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEV 1297
Query: 3269 LVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFG 3328
L L+ + S I + + L + LE N S + E AVR
Sbjct: 1298 LDSLENLMRHSEDNPNQIRILAQTLTDGGVMDELINEELETFN---SRWRELHEEAVRRQ 1354
Query: 3329 KTL--IIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFI 3386
K L IQ E L+ L++ L + I DK+
Sbjct: 1355 KLLEQSIQSAQETEKSLH-LIQESLTFIDKQLAAYIADKV-------------------- 1393
Query: 3387 PPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEE--DKKIQLAKLE 3444
DAA + E +S L ++L + +E ++L Q + KK+Q ++
Sbjct: 1394 --DAAQMPQEAQ--KIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQIDVAQKKLQDVSMK 1449
Query: 3445 ESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAE 3504
L + A + + E+K + L++ K ++ E +Q L+ + Y L+E
Sbjct: 1450 FRLFQKPANFEQRLQESKMI---LDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSE 1506
Query: 3505 SASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYE 3564
S++ +I R + K+ +EN ++ + +++L+ E
Sbjct: 1507 VKSEVEMVIKT-------------------GRQIVQKKQTENPKE-LDERVTALKLHYNE 1546
Query: 3565 YICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSW 3624
+ + QL L R M E+ EW T + + +++ + +PS
Sbjct: 1547 LGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMEL--------TKRSAVEGMPSN 1598
Query: 3625 IDQERSWAVATLK 3637
+D E +W AT K
Sbjct: 1599 LDSEVAWGKATQK 1611
Score = 38.1 bits (87), Expect = 0.19
Identities = 58/335 (17%), Positives = 138/335 (41%), Gaps = 41/335 (12%)
Query: 2886 KKKELLKRQSHLQAGVSKLNEAKALVDELNRKAG----EQSVLLKTKQDEADAALQMITV 2941
K ++L ++ +HL +S + + ++ N++ E + ++ KQ + + L
Sbjct: 2321 KLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILS---- 2376
Query: 2942 SMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLS 3001
Q ++K + +K ++ E++ + N++ EL+ QP + +G ++++
Sbjct: 2377 KGQHLYKEKPATQPVKRKL-EDLSSEWKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT 2435
Query: 3002 -----------EIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATF 3050
I L MP ++ ++ + F+ +W + +L+
Sbjct: 2436 LVTQPVVTKETAISKLEMPSSLMLEV-----PALADFNRAWTELTDWLSLLD-----QVI 2485
Query: 3051 DARNISKEIRESVEELLFKNKGSFDPKNAKRAS-----TAAAPLAAWVKANIQYSHVLER 3105
++ + E + E++ K K + +R TAA L + + +R
Sbjct: 2486 KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDR 2545
Query: 3106 IHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEA--EVS 3163
I ++ + ++ +L ++R+++L E+L Q + +E Q AKLE+ E
Sbjct: 2546 IERIQNQWDEVQEHL---QNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGP 2602
Query: 3164 KAQETIKAAEVLINQLDREHKRWNAQVVEITEELA 3198
+ I+ QL ++ ++W V++ +LA
Sbjct: 2603 YTVDAIQKKITETKQLAKDLRQWQTN-VDVANDLA 2636
>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
Length = 3562
Score = 55.8 bits (133), Expect = 9e-07
Identities = 144/733 (19%), Positives = 269/733 (36%), Gaps = 97/733 (13%)
Query: 2914 LNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNK 2973
+ ++ GE L + Q++ + T + + + +E+ R + E +IE R K
Sbjct: 852 MEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISR---KYQSEFEEIEGRWKK 908
Query: 2974 IDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVS 3033
+ +L E + E ++ LR + I+ + + + + W +
Sbjct: 909 LSSQLVEHCQKLEE--------------QMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPA 954
Query: 3034 M--KSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAA 3091
+ L K+ + + D + I + SV E K K +P+ A R T L
Sbjct: 955 LGDSEILKKQLKQCRLLVSDIQTIQPSLN-SVNEGGQKIKNEAEPEFASRLETELKEL-- 1011
Query: 3092 WVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEK-FQS 3150
N Q+ H+ ++++ + L+ L+KT ++ L E+ + Q E E+ F+
Sbjct: 1012 ----NTQWDHMCQQVY---ARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEY 1064
Query: 3151 RT-SEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAA 3209
+T E K E+ +A+E + E + L AQ + +E L K +
Sbjct: 1065 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQE--ALKKELETLTT 1122
Query: 3210 FITYLSAAPESLRKTCLEEWTKSAGLEKF-DLRRFLCTESEQLIWKSEGLPSDDLSIENA 3268
+L KT E W L + + E E + +E +P I
Sbjct: 1123 NYQWLCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEV 1182
Query: 3269 LVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFG 3328
L L+ + S I + + L + LE N S + E AVR
Sbjct: 1183 LDSLENLMRHSEDNPNQIRILAQTLTDGGVMDELINEELETFN---SRWRELHEEAVRRQ 1239
Query: 3329 KTL--IIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFI 3386
K L IQ E L+ L++ L + I DK+
Sbjct: 1240 KLLEQSIQSAQETEKSLH-LIQESLTFIDKQLAAYIADKV-------------------- 1278
Query: 3387 PPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEE--DKKIQLAKLE 3444
DAA + E +S L ++L + +E ++L Q + KK+Q ++
Sbjct: 1279 --DAAQMPQEAQ--KIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQIDVAQKKLQDVSMK 1334
Query: 3445 ESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAE 3504
L + A + + E+K + L++ K ++ E +Q L+ + Y L+E
Sbjct: 1335 FRLFQKPANFEQRLQESKMI---LDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSE 1391
Query: 3505 SASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYE 3564
S++ +I R + K+ +EN ++ + +++L+ E
Sbjct: 1392 VKSEVEMVIKT-------------------GRQIVQKKQTENPKE-LDERVTALKLHYNE 1431
Query: 3565 YICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSW 3624
+ + QL L R M E+ EW T + + +++ + +PS
Sbjct: 1432 LGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMEL--------TKRSAVEGMPSN 1483
Query: 3625 IDQERSWAVATLK 3637
+D E +W AT K
Sbjct: 1484 LDSEVAWGKATQK 1496
Score = 38.1 bits (87), Expect = 0.19
Identities = 58/335 (17%), Positives = 138/335 (41%), Gaps = 41/335 (12%)
Query: 2886 KKKELLKRQSHLQAGVSKLNEAKALVDELNRKAG----EQSVLLKTKQDEADAALQMITV 2941
K ++L ++ +HL +S + + ++ N++ E + ++ KQ + + L
Sbjct: 2206 KLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILS---- 2261
Query: 2942 SMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLS 3001
Q ++K + +K ++ E++ + N++ EL+ QP + +G ++++
Sbjct: 2262 KGQHLYKEKPATQPVKRKL-EDLSSEWKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT 2320
Query: 3002 -----------EIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATF 3050
I L MP ++ ++ + F+ +W + +L+
Sbjct: 2321 LVTQPVVTKETAISKLEMPSSLMLEV-----PALADFNRAWTELTDWLSLLD-----QVI 2370
Query: 3051 DARNISKEIRESVEELLFKNKGSFDPKNAKRAS-----TAAAPLAAWVKANIQYSHVLER 3105
++ + E + E++ K K + +R TAA L + + +R
Sbjct: 2371 KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDR 2430
Query: 3106 IHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEA--EVS 3163
I ++ + ++ +L ++R+++L E+L Q + +E Q AKLE+ E
Sbjct: 2431 IERIQNQWDEVQEHL---QNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGP 2487
Query: 3164 KAQETIKAAEVLINQLDREHKRWNAQVVEITEELA 3198
+ I+ QL ++ ++W V++ +LA
Sbjct: 2488 YTVDAIQKKITETKQLAKDLRQWQTN-VDVANDLA 2521
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 55.8 bits (133), Expect = 9e-07
Identities = 144/733 (19%), Positives = 269/733 (36%), Gaps = 97/733 (13%)
Query: 2914 LNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNK 2973
+ ++ GE L + Q++ + T + + + +E+ R + E +IE R K
Sbjct: 971 MEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISR---KYQSEFEEIEGRWKK 1027
Query: 2974 IDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVS 3033
+ +L E + E ++ LR + I+ + + + + W +
Sbjct: 1028 LSSQLVEHCQKLEE--------------QMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPA 1073
Query: 3034 M--KSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAA 3091
+ L K+ + + D + I + SV E K K +P+ A R T L
Sbjct: 1074 LGDSEILKKQLKQCRLLVSDIQTIQPSLN-SVNEGGQKIKNEAEPEFASRLETELKEL-- 1130
Query: 3092 WVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEK-FQS 3150
N Q+ H+ ++++ + L+ L+KT ++ L E+ + Q E E+ F+
Sbjct: 1131 ----NTQWDHMCQQVY---ARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEY 1183
Query: 3151 RT-SEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAA 3209
+T E K E+ +A+E + E + L AQ + +E L K +
Sbjct: 1184 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQE--ALKKELETLTT 1241
Query: 3210 FITYLSAAPESLRKTCLEEWTKSAGLEKF-DLRRFLCTESEQLIWKSEGLPSDDLSIENA 3268
+L KT E W L + + E E + +E +P I
Sbjct: 1242 NYQWLCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEV 1301
Query: 3269 LVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFG 3328
L L+ + S I + + L + LE N S + E AVR
Sbjct: 1302 LDSLENLMRHSEDNPNQIRILAQTLTDGGVMDELINEELETFN---SRWRELHEEAVRRQ 1358
Query: 3329 KTL--IIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFI 3386
K L IQ E L+ L++ L + I DK+
Sbjct: 1359 KLLEQSIQSAQETEKSLH-LIQESLTFIDKQLAAYIADKV-------------------- 1397
Query: 3387 PPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEE--DKKIQLAKLE 3444
DAA + E +S L ++L + +E ++L Q + KK+Q ++
Sbjct: 1398 --DAAQMPQEAQ--KIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQIDVAQKKLQDVSMK 1453
Query: 3445 ESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAE 3504
L + A + + E+K + L++ K ++ E +Q L+ + Y L+E
Sbjct: 1454 FRLFQKPANFEQRLQESKMI---LDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSE 1510
Query: 3505 SASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYE 3564
S++ +I R + K+ +EN ++ + +++L+ E
Sbjct: 1511 VKSEVEMVIKT-------------------GRQIVQKKQTENPKE-LDERVTALKLHYNE 1550
Query: 3565 YICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSW 3624
+ + QL L R M E+ EW T + + +++ + +PS
Sbjct: 1551 LGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMEL--------TKRSAVEGMPSN 1602
Query: 3625 IDQERSWAVATLK 3637
+D E +W AT K
Sbjct: 1603 LDSEVAWGKATQK 1615
Score = 38.1 bits (87), Expect = 0.19
Identities = 58/335 (17%), Positives = 138/335 (41%), Gaps = 41/335 (12%)
Query: 2886 KKKELLKRQSHLQAGVSKLNEAKALVDELNRKAG----EQSVLLKTKQDEADAALQMITV 2941
K ++L ++ +HL +S + + ++ N++ E + ++ KQ + + L
Sbjct: 2325 KLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILS---- 2380
Query: 2942 SMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLS 3001
Q ++K + +K ++ E++ + N++ EL+ QP + +G ++++
Sbjct: 2381 KGQHLYKEKPATQPVKRKL-EDLSSEWKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT 2439
Query: 3002 -----------EIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATF 3050
I L MP ++ ++ + F+ +W + +L+
Sbjct: 2440 LVTQPVVTKETAISKLEMPSSLMLEV-----PALADFNRAWTELTDWLSLLD-----QVI 2489
Query: 3051 DARNISKEIRESVEELLFKNKGSFDPKNAKRAS-----TAAAPLAAWVKANIQYSHVLER 3105
++ + E + E++ K K + +R TAA L + + +R
Sbjct: 2490 KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDR 2549
Query: 3106 IHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEA--EVS 3163
I ++ + ++ +L ++R+++L E+L Q + +E Q AKLE+ E
Sbjct: 2550 IERIQNQWDEVQEHL---QNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGP 2606
Query: 3164 KAQETIKAAEVLINQLDREHKRWNAQVVEITEELA 3198
+ I+ QL ++ ++W V++ +LA
Sbjct: 2607 YTVDAIQKKITETKQLAKDLRQWQTN-VDVANDLA 2640
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 155,556,849
Number of Sequences: 37866
Number of extensions: 6828234
Number of successful extensions: 25853
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 383
Number of HSP's that attempted gapping in prelim test: 21263
Number of HSP's gapped (non-prelim): 4029
length of query: 4314
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4191
effective length of database: 13,590,000
effective search space: 56955690000
effective search space used: 56955690000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.