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Search of human proteins with 32129209
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
(183 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 363 e-101
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 338 2e-93
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 320 6e-88
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 224 2e-59
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 224 2e-59
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 221 3e-58
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 221 3e-58
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 178 3e-45
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 177 4e-45
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 176 1e-44
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 176 1e-44
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 175 2e-44
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 174 4e-44
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 174 4e-44
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 170 5e-43
gi|21703367 Di-Ras2 [Homo sapiens] 165 2e-41
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 164 4e-41
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 164 4e-41
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 162 1e-40
gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 158 3e-39
gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 158 3e-39
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 156 8e-39
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 154 3e-38
gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo... 132 1e-31
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 131 4e-31
gi|169160721 PREDICTED: similar to related RAS viral (r-ras) onc... 128 2e-30
gi|169161589 PREDICTED: similar to related RAS viral (r-ras) onc... 128 2e-30
gi|169161292 PREDICTED: similar to related RAS viral (r-ras) onc... 128 2e-30
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 127 4e-30
gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens] 117 7e-27
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 363 bits (933), Expect = e-101
Identities = 183/183 (100%), Positives = 183/183 (100%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC 180
EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC
Sbjct: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC 180
Query: 181 VVQ 183
VVQ
Sbjct: 181 VVQ 183
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 338 bits (866), Expect = 2e-93
Identities = 167/183 (91%), Positives = 176/183 (96%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI+RVKRYEKVP+ILVGNKVDL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC 180
E EREV SSEGRALA+EWGCPFMETSAKSK+MVDELFAEIVRQMNY++ P+K D CC+ C
Sbjct: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC 180
Query: 181 VVQ 183
+Q
Sbjct: 181 NIQ 183
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 320 bits (819), Expect = 6e-88
Identities = 157/182 (86%), Positives = 170/182 (93%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYKVVVLGSGGVGKSALTVQFVTG+FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI+RVKRYE+VP+ILVGNKVDL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC 180
E EREV EG+ALA+EW CPFMETSAK+K+ VDELFAEIVRQMNY++ P + CC+ C
Sbjct: 121 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC 180
Query: 181 VV 182
V+
Sbjct: 181 VI 182
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 224 bits (572), Expect = 2e-59
Identities = 113/183 (61%), Positives = 144/183 (78%), Gaps = 1/183 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK E VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEW-GCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTT 179
E ER V +G+ LA++W C F+E+SAKSK V+E+F ++VRQ+N + EK+ +
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
Query: 180 CVV 182
C++
Sbjct: 181 CLL 183
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 224 bits (572), Expect = 2e-59
Identities = 113/183 (61%), Positives = 144/183 (78%), Gaps = 1/183 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK E VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEW-GCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTT 179
E ER V +G+ LA++W C F+E+SAKSK V+E+F ++VRQ+N + EK+ +
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
Query: 180 CVV 182
C++
Sbjct: 181 CLL 183
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 221 bits (563), Expect = 3e-58
Identities = 109/166 (65%), Positives = 137/166 (82%), Gaps = 1/166 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD+ +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK + VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEW-GCPFMETSAKSKSMVDELFAEIVRQMN 165
E ER V +G+ LA++W C F+E+SAKSK V+E+F ++VRQ+N
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQIN 166
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 221 bits (563), Expect = 3e-58
Identities = 109/166 (65%), Positives = 137/166 (82%), Gaps = 1/166 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD+ +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK + VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEW-GCPFMETSAKSKSMVDELFAEIVRQMN 165
E ER V +G+ LA++W C F+E+SAKSK V+E+F ++VRQ+N
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQIN 166
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 178 bits (451), Expect = 3e-45
Identities = 84/164 (51%), Positives = 125/164 (76%), Gaps = 1/164 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK E VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164
P R V + + + LA+ +G PF+ETSAK++ VD+ F +VR++
Sbjct: 121 -PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREI 163
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 177 bits (449), Expect = 4e-45
Identities = 83/164 (50%), Positives = 125/164 (76%), Gaps = 1/164 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK E VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164
P R V + + + LA+ +G PF+ETSAK++ V++ F +VR++
Sbjct: 121 -PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREI 163
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 176 bits (445), Expect = 1e-44
Identities = 85/185 (45%), Positives = 131/185 (70%), Gaps = 6/185 (3%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSL-----PEKQDQ 175
R V S + + LA+ +G P++ETSAK++ V++ F +VR++ L P++
Sbjct: 121 -AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGP 179
Query: 176 CCTTC 180
C +C
Sbjct: 180 GCMSC 184
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 176 bits (445), Expect = 1e-44
Identities = 85/185 (45%), Positives = 131/185 (70%), Gaps = 6/185 (3%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSL-----PEKQDQ 175
R V S + + LA+ +G P++ETSAK++ V++ F +VR++ L P++
Sbjct: 121 -AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGP 179
Query: 176 CCTTC 180
C +C
Sbjct: 180 GCMSC 184
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 175 bits (443), Expect = 2e-44
Identities = 83/176 (47%), Positives = 129/176 (73%), Gaps = 4/176 (2%)
Query: 2 REYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61
REYKVV+LG+GGVGKSA+T+QF++ F + +DPTIED Y+ ++ +D+ P+ L+ILDTAG
Sbjct: 19 REYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQ 78
Query: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLE 121
+F +MR+ Y++ G+GFI+ YS+ ++QSFQ+ ++ I +V+ ++PL+LVGNK+DLE
Sbjct: 79 AEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLE 138
Query: 122 PEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM----NYSSLPEKQ 173
R+V + EG +LAQE+ C F ETSA + +D+ F +VR++ + SL EK+
Sbjct: 139 QFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKESMPSLMEKK 194
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 174 bits (441), Expect = 4e-44
Identities = 82/164 (50%), Positives = 123/164 (75%), Gaps = 1/164 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164
P R V + + LA+ +G PF+ETSAK++ V++ F +VR++
Sbjct: 121 -PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREI 163
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 174 bits (441), Expect = 4e-44
Identities = 80/163 (49%), Positives = 121/163 (74%)
Query: 2 REYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61
REYK+V+LG+GGVGKSA+T+QF++ F E +DPTIED Y+ I +D P+ L+ILDTAG
Sbjct: 20 REYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQ 79
Query: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLE 121
+F +MRD Y++ G+GFI+ YS+ +++SF +++ + I RV+R + P++LVGNK DL+
Sbjct: 80 AEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLK 139
Query: 122 PEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164
R+V EG ALA+E+ CPF ETSA + +D++F +VR++
Sbjct: 140 QLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVREI 182
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 170 bits (431), Expect = 5e-43
Identities = 80/173 (46%), Positives = 126/173 (72%), Gaps = 1/173 (0%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
+KV+++GSGGVGKSALT+QF+ F+E Y+PT D YRK++ +D ++ILDTAG E
Sbjct: 15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 74
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYE-KVPLILVGNKVDLEP 122
+A++RD Y ++G+GF+LV+S+ +SF R+QI+RVK E K+PL++VGNK DLE
Sbjct: 75 YAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEE 134
Query: 123 EREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQ 175
R+V E R+ A+EWG ++ETSAK+++ VD++F +++R++ + E +D+
Sbjct: 135 RRQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDK 187
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 165 bits (418), Expect = 2e-41
Identities = 83/160 (51%), Positives = 110/160 (68%), Gaps = 1/160 (0%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
+Y+V V G+GGVGKS+L ++FV GTF E Y PT+ED YR+ I D S L+I DT G+
Sbjct: 7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSH 66
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVK-RYEKVPLILVGNKVDLE 121
QF +M+ L I G FILVYS+ ++QS +++KP+ +QI +K E +P++LVGNK D
Sbjct: 67 QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDES 126
Query: 122 PEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIV 161
P REV SSE ALA+ W C FMETSAK V ELF E++
Sbjct: 127 PSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELL 166
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 164 bits (415), Expect = 4e-41
Identities = 77/150 (51%), Positives = 115/150 (76%), Gaps = 1/150 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSK 150
R V S + + LA+ +G P++ETSAK++
Sbjct: 121 -AARTVESRQAQDLARSYGIPYIETSAKTR 149
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 164 bits (415), Expect = 4e-41
Identities = 77/160 (48%), Positives = 117/160 (73%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
+Y++VV+G GGVGKSALT+QF+ F+ YDPTIED Y K+ +D + L+ILDTAG E
Sbjct: 14 KYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQE 73
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEP 122
+F +MR+ Y++ G+GF+LV+S+ ++ SF++I + QI+RVK ++ P+IL+GNK DL+
Sbjct: 74 EFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDH 133
Query: 123 EREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVR 162
+R+V EG+ LA++ +ME SAK + VD+ F E+VR
Sbjct: 134 QRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVR 173
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 162 bits (411), Expect = 1e-40
Identities = 74/172 (43%), Positives = 122/172 (70%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
+KV+++GSGGVGKSALT+QF+ F+E Y+PT D YRK++ +D ++ILDTAG E
Sbjct: 15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 74
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPE 123
+A++RD Y ++G+GF+ V+S+ +SF R+QI+RVK E VP +LVGNK DLE +
Sbjct: 75 YAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDK 134
Query: 124 REVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQ 175
R+V E + A++W ++ETSAK+++ VD++F +++R++ + + +++
Sbjct: 135 RQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEK 186
>gi|145386506 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 158 bits (399), Expect = 3e-39
Identities = 78/173 (45%), Positives = 118/173 (68%), Gaps = 2/173 (1%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
YK+VV+G GGVGKSALT+QF F+ YDPTIED Y K E+D+ ++L++LDTAG E+
Sbjct: 14 YKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEE 73
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPE 123
F++MR+ Y++ G GF++VYS+ ++ SF+ + I+RVK E P+ILV NKVDL
Sbjct: 74 FSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHL 133
Query: 124 REVMSSEGRALAQEWGCPFMETSAKSKSM-VDELFAEIVRQMNYSSLPEKQDQ 175
R++ +G+ +A + P++ETSAK + VD+ F ++VR + +PEK +
Sbjct: 134 RKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR-QQIPEKSQK 185
>gi|145386562 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 158 bits (399), Expect = 3e-39
Identities = 78/173 (45%), Positives = 118/173 (68%), Gaps = 2/173 (1%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
YK+VV+G GGVGKSALT+QF F+ YDPTIED Y K E+D+ ++L++LDTAG E+
Sbjct: 14 YKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEE 73
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPE 123
F++MR+ Y++ G GF++VYS+ ++ SF+ + I+RVK E P+ILV NKVDL
Sbjct: 74 FSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHL 133
Query: 124 REVMSSEGRALAQEWGCPFMETSAKSKSM-VDELFAEIVRQMNYSSLPEKQDQ 175
R++ +G+ +A + P++ETSAK + VD+ F ++VR + +PEK +
Sbjct: 134 RKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR-QQIPEKSQK 185
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 156 bits (395), Expect = 8e-39
Identities = 77/159 (48%), Positives = 109/159 (68%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
+K+VV+G GGVGKSALT+QF+ F+ YDPTIED Y K VD P+ L+ILDTAG E+
Sbjct: 30 HKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEE 89
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPE 123
F +MR+ Y++ G GF+LV+++ ++QSF ++ + QI+RVK + P++LVGNK DLE +
Sbjct: 90 FGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQ 149
Query: 124 REVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVR 162
R+V SE A + E SAK + VDE F ++VR
Sbjct: 150 RQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVR 188
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 154 bits (390), Expect = 3e-38
Identities = 81/160 (50%), Positives = 112/160 (70%), Gaps = 2/160 (1%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
+Y+VVV G+GGVGKS+L ++FV GTF + Y PTIED YR+ I D S L+I DT G+
Sbjct: 7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSH 66
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVK-RYEKVPLILVGNKVDLE 121
QF +M+ L I G FILV+S+ ++QS +++ P+ IV++K E +P++LVGNK D E
Sbjct: 67 QFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-E 125
Query: 122 PEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIV 161
+REV + E +A+AQEW C FMETSAK V ELF E++
Sbjct: 126 TQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELL 165
>gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo
sapiens]
Length = 199
Score = 132 bits (333), Expect = 1e-31
Identities = 68/163 (41%), Positives = 105/163 (64%), Gaps = 2/163 (1%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
E K+ + G GVGKSAL V+F+T FI +YDPT+E YR + +D +EILDTAG E
Sbjct: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEP 122
R+ +++ G+GF+LVY + ++ SF+++ P+++ + +K+ + V LILVGNK DL+
Sbjct: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
Query: 123 EREVMSSEGRALAQEWGCPFMETSA-KSKSMVDELFAEIVRQM 164
R+V + EG LA E C F E SA + + E+F E+ R++
Sbjct: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREV 167
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 131 bits (329), Expect = 4e-31
Identities = 64/164 (39%), Positives = 104/164 (63%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
+R KVV+LG VGK++L QFV G F E YDPT+E+ Y K + + L ++DTAG
Sbjct: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
++++ + +I G++LVYS+ + SFQ I+ + ++ +VP++LVGNK DL
Sbjct: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
Query: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164
PEREV + EG+ LA+ WG FME+SA+ + +F ++++++
Sbjct: 124 SPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
>gi|169160721 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 128 bits (322), Expect = 2e-30
Identities = 61/135 (45%), Positives = 94/135 (69%)
Query: 28 FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQ 87
F+ YDPT ED Y K+ +D + L+ILDTAG E+ +MR+ Y++ G+GF+LV+S+ ++
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 88 QSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSA 147
SF++I + QI+RVK ++ P+IL+GNK DL+ +R+V EGR LA++ +ME SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 148 KSKSMVDELFAEIVR 162
K + VD+ F E+VR
Sbjct: 140 KIRMNVDQAFHELVR 154
>gi|169161589 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 128 bits (322), Expect = 2e-30
Identities = 61/135 (45%), Positives = 94/135 (69%)
Query: 28 FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQ 87
F+ YDPT ED Y K+ +D + L+ILDTAG E+ +MR+ Y++ G+GF+LV+S+ ++
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 88 QSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSA 147
SF++I + QI+RVK ++ P+IL+GNK DL+ +R+V EGR LA++ +ME SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 148 KSKSMVDELFAEIVR 162
K + VD+ F E+VR
Sbjct: 140 KIRMNVDQAFHELVR 154
>gi|169161292 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 128 bits (322), Expect = 2e-30
Identities = 61/135 (45%), Positives = 94/135 (69%)
Query: 28 FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQ 87
F+ YDPT ED Y K+ +D + L+ILDTAG E+ +MR+ Y++ G+GF+LV+S+ ++
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 88 QSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSA 147
SF++I + QI+RVK ++ P+IL+GNK DL+ +R+V EGR LA++ +ME SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 148 KSKSMVDELFAEIVR 162
K + VD+ F E+VR
Sbjct: 140 KIRMNVDQAFHELVR 154
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 127 bits (320), Expect = 4e-30
Identities = 62/157 (39%), Positives = 101/157 (64%)
Query: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQF 64
K+ +LG VGKS+LT+QFV G F++ YDPTIE+ + K I V+ L+++DTAG +++
Sbjct: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
Query: 65 ASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPER 124
+ Y + G+ILVYS+ + +SF+ IK + +++ + ++P++LVGNK DL ER
Sbjct: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
Query: 125 EVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIV 161
+ EG+ALA+ W F+E+SAK ++F I+
Sbjct: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRII 164
>gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens]
Length = 281
Score = 117 bits (292), Expect = 7e-27
Identities = 67/164 (40%), Positives = 97/164 (59%), Gaps = 10/164 (6%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Y++V+LGS VGK+A+ +F+TG F + Y PTIEDF+RK + L+ILDT+G
Sbjct: 25 YRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHP 84
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIV--------RVKRYEKVPLILVG 115
F +MR L I G FILV+SL N+ SF++++ +R QI+ + K VPL++ G
Sbjct: 85 FPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICG 144
Query: 116 NKVDLEPEREVMSSEGRALAQE--WGCPFMETSAKSKSMVDELF 157
NK D + REV E L + C + E SAK S +D++F
Sbjct: 145 NKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMF 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,226,340
Number of Sequences: 37866
Number of extensions: 236072
Number of successful extensions: 1068
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 630
Number of HSP's gapped (non-prelim): 265
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.