BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31559833 ES cell expressed Ras [Homo sapiens] (233 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31559833 ES cell expressed Ras [Homo sapiens] 481 e-136 gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 155 4e-38 gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 148 4e-36 gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 145 3e-35 gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 144 5e-35 gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 144 5e-35 gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 130 1e-30 gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 115 4e-26 gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 114 5e-26 gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 114 5e-26 gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 114 5e-26 gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 114 9e-26 gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 112 4e-25 gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 110 8e-25 gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 110 1e-24 gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 110 1e-24 gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 110 1e-24 gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 108 4e-24 gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 108 5e-24 gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 108 5e-24 gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 107 9e-24 gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 100 8e-22 gi|21703367 Di-Ras2 [Homo sapiens] 91 8e-19 gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 85 6e-17 gi|169160721 PREDICTED: similar to related RAS viral (r-ras) onc... 84 8e-17 gi|169161589 PREDICTED: similar to related RAS viral (r-ras) onc... 84 8e-17 gi|169161292 PREDICTED: similar to related RAS viral (r-ras) onc... 84 8e-17 gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 82 4e-16 gi|5032041 Ras homolog enriched in brain [Homo sapiens] 79 3e-15 gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap... 77 1e-14 >gi|31559833 ES cell expressed Ras [Homo sapiens] Length = 233 Score = 481 bits (1239), Expect = e-136 Identities = 233/233 (100%), Positives = 233/233 (100%) Query: 1 MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQ 60 MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQ Sbjct: 1 MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQ 60 Query: 61 LNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVF 120 LNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVF Sbjct: 61 LNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVF 120 Query: 121 ALDDPSSLIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVET 180 ALDDPSSLIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVET Sbjct: 121 ALDDPSSLIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVET 180 Query: 181 SAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA 233 SAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA Sbjct: 181 SAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA 233 >gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] Length = 188 Score = 155 bits (391), Expect = 4e-38 Identities = 88/186 (47%), Positives = 122/186 (65%), Gaps = 6/186 (3%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 + EYK VVVGA GVGKSALTIQL FV+++DPTI+DSY K++ +D C+L++LDTAG Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSSLIQL----QQIWATWGPHPAQPLVLVGNKCD 154 Q + A+RDQ + +G L VFA+++ S + +QI P+VLVGNKCD Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDV-PMVLVGNKCD 119 Query: 155 LVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARS 214 L + D A LA S+G F+ETSAKTRQGV++AF LV EI++ +E M+K+ + Sbjct: 120 LPSRTVDT-KQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKK 178 Query: 215 CREKTR 220 + KT+ Sbjct: 179 KKSKTK 184 >gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo sapiens] Length = 189 Score = 148 bits (373), Expect = 4e-36 Identities = 85/167 (50%), Positives = 111/167 (66%), Gaps = 6/167 (3%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 + EYK VVVGA GVGKSALTIQL FV+++DPTI+DSY K++ +D C+L++LDTAG Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSSLIQL----QQIWATWGPHPAQPLVLVGNKCD 154 Q + A+RDQ + +G L VFA+++ S + +QI P+VLVGNKCD Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDV-PMVLVGNKCD 119 Query: 155 LVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQR 201 L T D A LA S+G F+ETSAKTRQGVE+AF LV EI++ Sbjct: 120 LPTRTVDT-KQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQ 165 >gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] Length = 189 Score = 145 bits (366), Expect = 3e-35 Identities = 86/182 (47%), Positives = 117/182 (64%), Gaps = 7/182 (3%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 + EYK VVVGA GVGKSALTIQL FV+++DPTI+DSY K++ +D C+L++LDTAG Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSSLIQL----QQIWATWGPHPAQPLVLVGNKCD 154 Q + A+RDQ + +G L VFA+++ S + +QI P+VLVGNKCD Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDV-PMVLVGNKCD 119 Query: 155 LVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQ-EAMAKEPMAR 213 L + D A LA S+G F+ETSAKTRQ VE+AF LV EI++ + + ++KE Sbjct: 120 LPSRTVDT-KQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTP 178 Query: 214 SC 215 C Sbjct: 179 GC 180 >gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1 [Homo sapiens] Length = 189 Score = 144 bits (364), Expect = 5e-35 Identities = 81/166 (48%), Positives = 111/166 (66%), Gaps = 4/166 (2%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 + EYK VVVGA GVGKSALTIQL FV+++DPTI+DSY K++ +D C+L++LDTAG Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDL 155 Q + A+RDQ + +G L VFA+++ S + Q ++ P+VLVGNKCDL Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120 Query: 156 VTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQR 201 ++ A LA S+G ++ETSAKTRQGVE+AF LV EI++ Sbjct: 121 AARTVESR-QAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQ 165 >gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1 [Homo sapiens] Length = 189 Score = 144 bits (364), Expect = 5e-35 Identities = 81/166 (48%), Positives = 111/166 (66%), Gaps = 4/166 (2%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 + EYK VVVGA GVGKSALTIQL FV+++DPTI+DSY K++ +D C+L++LDTAG Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDL 155 Q + A+RDQ + +G L VFA+++ S + Q ++ P+VLVGNKCDL Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120 Query: 156 VTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQR 201 ++ A LA S+G ++ETSAKTRQGVE+AF LV EI++ Sbjct: 121 AARTVESR-QAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQ 165 >gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 2 [Homo sapiens] Length = 170 Score = 130 bits (327), Expect = 1e-30 Identities = 73/152 (48%), Positives = 100/152 (65%), Gaps = 4/152 (2%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 + EYK VVVGA GVGKSALTIQL FV+++DPTI+DSY K++ +D C+L++LDTAG Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDL 155 Q + A+RDQ + +G L VFA+++ S + Q ++ P+VLVGNKCDL Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120 Query: 156 VTTAGDAHAAAAALAHSWGAHFVETSAKTRQG 187 ++ A LA S+G ++ETSAKTRQG Sbjct: 121 AARTVESR-QAQDLARSYGIPYIETSAKTRQG 151 >gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo sapiens] Length = 206 Score = 115 bits (287), Expect = 4e-26 Identities = 68/189 (35%), Positives = 103/189 (54%), Gaps = 4/189 (2%) Query: 42 YKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAI 101 +K ++VG+ GVGKSALT+Q + FVED++PT DSY K++ LD + +++LDTAGQ Sbjct: 15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 74 Query: 102 HRALRDQCLAVCDGVLGVFALDDPSSLIQL----QQIWATWGPHPAQPLVLVGNKCDLVT 157 + A+RD +G L VF++ + S +QI PL++VGNK DL Sbjct: 75 YAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEE 134 Query: 158 TAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCRE 217 A + A WG +VETSAKTR V++ F L+ EI+ + + K+ + + Sbjct: 135 RRQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNGKKSSK 194 Query: 218 KTRHQKATC 226 + K C Sbjct: 195 NKKSFKERC 203 >gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 114 bits (286), Expect = 5e-26 Identities = 72/180 (40%), Positives = 97/180 (53%), Gaps = 6/180 (3%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK VV+G+ GVGKSALT+Q FVE +DPTI+DSY K++ +D C+L +LDTAG Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTE 62 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQLQ----QIWATWGPHPAQPLVLVGNKCDLV 156 A+RD + G V+++ S+ LQ QI P++LVGNKCDL Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDV-PMILVGNKCDLE 121 Query: 157 TTAGDAHAAAAALAHSW-GAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSC 215 LA W F+E+SAK++ V E F LV +I R K+P +SC Sbjct: 122 DERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSC 181 >gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 114 bits (286), Expect = 5e-26 Identities = 72/180 (40%), Positives = 97/180 (53%), Gaps = 6/180 (3%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK VV+G+ GVGKSALT+Q FVE +DPTI+DSY K++ +D C+L +LDTAG Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTE 62 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQLQ----QIWATWGPHPAQPLVLVGNKCDLV 156 A+RD + G V+++ S+ LQ QI P++LVGNKCDL Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDV-PMILVGNKCDLE 121 Query: 157 TTAGDAHAAAAALAHSW-GAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSC 215 LA W F+E+SAK++ V E F LV +I R K+P +SC Sbjct: 122 DERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSC 181 >gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a [Homo sapiens] Length = 204 Score = 114 bits (286), Expect = 5e-26 Identities = 77/204 (37%), Positives = 105/204 (51%), Gaps = 7/204 (3%) Query: 28 AQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSG 87 A A RD G +Y+ VVVG GVGKSALTIQ FV D+DPTI+DSY K+ +D Sbjct: 2 AAAGWRD-GSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR 60 Query: 88 DCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQ 144 L++LDTAGQ A+R+Q + +G L VF++ D S + + Q+ Sbjct: 61 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF 120 Query: 145 PLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQE 204 P++L+GNK DL LA ++E SAK R V++AF LV I++ QE Sbjct: 121 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE 180 Query: 205 AMAKEPMARSCREKTRHQKATCHC 228 + +EK K CHC Sbjct: 181 QECPPSPEPTRKEK---DKKGCHC 201 >gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 114 bits (284), Expect = 9e-26 Identities = 64/178 (35%), Positives = 101/178 (56%), Gaps = 3/178 (1%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK VV+G+ GVGKSALT+Q F+E +DPTI+D Y KE+ +DS +L +LDTAG Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQLQQI---WATWGPHPAQPLVLVGNKCDLVT 157 ++RD + G + V++L + S ++ + + P++LVGNK DL + Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLES 122 Query: 158 TAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSC 215 + + ALA WG F+ETSAK++ V+E F+ +V ++ + +P +C Sbjct: 123 EREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC 180 >gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapiens] Length = 218 Score = 112 bits (279), Expect = 4e-25 Identities = 69/166 (41%), Positives = 95/166 (57%), Gaps = 3/166 (1%) Query: 42 YKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAI 101 +K VVVG GVGKSALTIQ FV D+DPTI+DSY K ++D L++LDTAGQ Sbjct: 30 HKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEE 89 Query: 102 HRALRDQCLAVCDGVLGVFALDDPSSLIQLQQIWA---TWGPHPAQPLVLVGNKCDLVTT 158 A+R+Q + G L VFA++D S ++ +++ P+VLVGNK DL + Sbjct: 90 FGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQ 149 Query: 159 AGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQE 204 + A+A S + E SAK R V+EAF LV +++ QE Sbjct: 150 RQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQE 195 >gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 110 bits (276), Expect = 8e-25 Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 3/178 (1%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK VV+G+ GVGKSALT+Q F+E +DPTI+D Y KE+ +DS +L +LDTAG Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQLQQI---WATWGPHPAQPLVLVGNKCDLVT 157 ++RD + G + V++L + S ++ + + P++LVGNK DL Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEG 122 Query: 158 TAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSC 215 ++ ALA W F+ETSAK + V+E F+ +V ++ + E +C Sbjct: 123 EREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC 180 >gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 110 bits (275), Expect = 1e-24 Identities = 71/181 (39%), Positives = 96/181 (53%), Gaps = 6/181 (3%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK VV+G+ GVGKSALT+Q FVE +DPTI+DSY K++ +D+ C+L +LDTAG Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTE 62 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQLQ----QIWATWGPHPAQPLVLVGNKCDLV 156 A+RD + G V+++ S+ LQ QI P++LVGNKCDL Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDV-PMILVGNKCDLE 121 Query: 157 TTAGDAHAAAAALAHSW-GAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSC 215 LA W F+E+SAK++ V E F LV +I R K SC Sbjct: 122 DERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSC 181 Query: 216 R 216 + Sbjct: 182 Q 182 >gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 110 bits (275), Expect = 1e-24 Identities = 71/181 (39%), Positives = 96/181 (53%), Gaps = 6/181 (3%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK VV+G+ GVGKSALT+Q FVE +DPTI+DSY K++ +D+ C+L +LDTAG Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTE 62 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQLQ----QIWATWGPHPAQPLVLVGNKCDLV 156 A+RD + G V+++ S+ LQ QI P++LVGNKCDL Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDV-PMILVGNKCDLE 121 Query: 157 TTAGDAHAAAAALAHSW-GAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSC 215 LA W F+E+SAK++ V E F LV +I R K SC Sbjct: 122 DERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSC 181 Query: 216 R 216 + Sbjct: 182 Q 182 >gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 110 bits (275), Expect = 1e-24 Identities = 63/162 (38%), Positives = 94/162 (58%), Gaps = 3/162 (1%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK VV+G+ GVGKSALT+Q F+E +DPTI+D Y KE+ +DS +L +LDTAG Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQLQQI---WATWGPHPAQPLVLVGNKCDLVT 157 ++RD + G + V++L + S ++ + + PL+LVGNK DL Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEP 122 Query: 158 TAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEI 199 + ALA WG F+ETSAK++ V+E F+ +V ++ Sbjct: 123 EREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164 >gi|5902050 Ras-like without CAAX 1 [Homo sapiens] Length = 219 Score = 108 bits (270), Expect = 4e-24 Identities = 65/167 (38%), Positives = 94/167 (56%), Gaps = 3/167 (1%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK V++GA GVGKSA+T+Q F EDHDPTI+D+Y + +D L++LDTAGQA Sbjct: 21 EYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQA 80 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDLVT 157 A+RDQ + +G + +++ D S + + +Q+ P+VLVGNK DL Sbjct: 81 EFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLKQ 140 Query: 158 TAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQE 204 ALA + F ETSA R +++ F LV EI+R ++ Sbjct: 141 LRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVREIRRKEK 187 >gi|145386506 muscle RAS oncogene homolog [Homo sapiens] Length = 208 Score = 108 bits (269), Expect = 5e-24 Identities = 72/192 (37%), Positives = 107/192 (55%), Gaps = 9/192 (4%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 LP YK VVVG GVGKSALTIQ + FV D+DPTI+DSY K +D+ IL+VLDTAG Sbjct: 11 LPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAG 70 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDL 155 Q A+R+Q + DG L V+++ D +S + + Q+ + P++LV NK DL Sbjct: 71 QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDL 130 Query: 156 VTTAGDAHAAAAALAHSWGAHFVETSAKTRQ-GVEEAFSLLVHEIQRV-QEAMAKEPMAR 213 + +A ++ETSAK V++AF H++ RV ++ + ++ + Sbjct: 131 MHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAF----HDLVRVIRQQIPEKSQKK 186 Query: 214 SCREKTRHQKAT 225 + K R +AT Sbjct: 187 KKKTKWRGDRAT 198 >gi|145386562 muscle RAS oncogene homolog [Homo sapiens] Length = 208 Score = 108 bits (269), Expect = 5e-24 Identities = 72/192 (37%), Positives = 107/192 (55%), Gaps = 9/192 (4%) Query: 39 LPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAG 98 LP YK VVVG GVGKSALTIQ + FV D+DPTI+DSY K +D+ IL+VLDTAG Sbjct: 11 LPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAG 70 Query: 99 QAIHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDL 155 Q A+R+Q + DG L V+++ D +S + + Q+ + P++LV NK DL Sbjct: 71 QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDL 130 Query: 156 VTTAGDAHAAAAALAHSWGAHFVETSAKTRQ-GVEEAFSLLVHEIQRV-QEAMAKEPMAR 213 + +A ++ETSAK V++AF H++ RV ++ + ++ + Sbjct: 131 MHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAF----HDLVRVIRQQIPEKSQKK 186 Query: 214 SCREKTRHQKAT 225 + K R +AT Sbjct: 187 KKKTKWRGDRAT 198 >gi|33946329 ras related v-ral simian leukemia viral oncogene homolog A [Homo sapiens] Length = 206 Score = 107 bits (267), Expect = 9e-24 Identities = 67/180 (37%), Positives = 100/180 (55%), Gaps = 5/180 (2%) Query: 42 YKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAI 101 +K ++VG+ GVGKSALT+Q + FVED++PT DSY K++ LD + +++LDTAGQ Sbjct: 15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 74 Query: 102 HRALRDQCLAVCDGVLGVFALDDPSSLIQL----QQIWATWGPHPAQPLVLVGNKCDLVT 157 + A+RD +G L VF++ + S +QI P +LVGNK DL Sbjct: 75 YAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENV-PFLLVGNKSDLED 133 Query: 158 TAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCRE 217 + A A W ++VETSAKTR V++ F L+ EI+ + +KE + R+ Sbjct: 134 KRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRK 193 >gi|4506533 Ras-like without CAAX 2 [Homo sapiens] Length = 217 Score = 100 bits (250), Expect = 8e-22 Identities = 63/168 (37%), Positives = 96/168 (57%), Gaps = 11/168 (6%) Query: 41 EYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100 EYK V++GA GVGKSA+T+Q F + HDPTI+D+Y ++ +D+ L++LDTAGQA Sbjct: 20 EYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQA 79 Query: 101 IHRALRDQCLAVCDGVLGVFALDDPSSLIQ-------LQQIWATWGPHPAQPLVLVGNKC 153 A+R+Q + +G + +++ D S + + Q+ T+ PLVLVGNK Sbjct: 80 EFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTY----EIPLVLVGNKI 135 Query: 154 DLVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQR 201 DL + +LA + F ETSA R +++AF LV EI++ Sbjct: 136 DLEQFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRK 183 >gi|21703367 Di-Ras2 [Homo sapiens] Length = 199 Score = 90.9 bits (224), Expect = 8e-19 Identities = 58/195 (29%), Positives = 100/195 (51%), Gaps = 6/195 (3%) Query: 38 QLPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTA 97 Q +Y+ V GA GVGKS+L ++ F E + PT++D+Y + ++ D C L + DT Sbjct: 4 QSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTT 63 Query: 98 GQAIHRALRDQCLAVCDGVLGVFALDDPSSLIQL----QQIWATWGPHPAQPLVLVGNKC 153 G A++ ++ + V+++ SL +L +QI G + P++LVGNKC Sbjct: 64 GSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKC 123 Query: 154 DLVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMAR 213 D + + A ALA +W F+ETSAK V+E F L++ +R ++ + + Sbjct: 124 DESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKR--RTVSLQIDGK 181 Query: 214 SCREKTRHQKATCHC 228 +++ R +K C Sbjct: 182 KSKQQKRKEKLKGKC 196 >gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] Length = 198 Score = 84.7 bits (208), Expect = 6e-17 Identities = 58/169 (34%), Positives = 86/169 (50%), Gaps = 6/169 (3%) Query: 38 QLPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTA 97 Q +Y+ VV GA GVGKS+L ++ F + + PTI+D+Y + ++ D C L + DT Sbjct: 4 QSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTT 63 Query: 98 GQAIHRALRDQCLAVCDGVLGVFALDDPSSLIQLQQIW----ATWGPHPAQPLVLVGNKC 153 G A++ ++ + VF++ SL +L I+ G P++LVGNKC Sbjct: 64 GSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKC 123 Query: 154 DLVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAF-SLLVHEIQR 201 D D A A+A W F+ETSAK V+E F LL E +R Sbjct: 124 DETQREVDTR-EAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRR 171 >gi|169160721 PREDICTED: similar to related RAS viral (r-ras) oncogene homolog 2 [Homo sapiens] Length = 185 Score = 84.3 bits (207), Expect = 8e-17 Identities = 56/166 (33%), Positives = 82/166 (49%), Gaps = 6/166 (3%) Query: 66 FVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDP 125 FV D+DPT +DSY K+ +D L++LDTAGQ A+R+Q + +G L VF++ D Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79 Query: 126 SS---LIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSA 182 S + + Q+ P++L+GNK DL LA ++E SA Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139 Query: 183 KTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHC 228 K R V++AF LV I++ QE + +EK K CHC Sbjct: 140 KIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEK---DKKGCHC 182 >gi|169161589 PREDICTED: similar to related RAS viral (r-ras) oncogene homolog 2 [Homo sapiens] Length = 185 Score = 84.3 bits (207), Expect = 8e-17 Identities = 56/166 (33%), Positives = 82/166 (49%), Gaps = 6/166 (3%) Query: 66 FVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDP 125 FV D+DPT +DSY K+ +D L++LDTAGQ A+R+Q + +G L VF++ D Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79 Query: 126 SS---LIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSA 182 S + + Q+ P++L+GNK DL LA ++E SA Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139 Query: 183 KTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHC 228 K R V++AF LV I++ QE + +EK K CHC Sbjct: 140 KIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEK---DKKGCHC 182 >gi|169161292 PREDICTED: similar to related RAS viral (r-ras) oncogene homolog 2 [Homo sapiens] Length = 185 Score = 84.3 bits (207), Expect = 8e-17 Identities = 56/166 (33%), Positives = 82/166 (49%), Gaps = 6/166 (3%) Query: 66 FVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDP 125 FV D+DPT +DSY K+ +D L++LDTAGQ A+R+Q + +G L VF++ D Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79 Query: 126 SS---LIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSA 182 S + + Q+ P++L+GNK DL LA ++E SA Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139 Query: 183 KTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHC 228 K R V++AF LV I++ QE + +EK K CHC Sbjct: 140 KIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEK---DKKGCHC 182 >gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] Length = 183 Score = 82.0 bits (201), Expect = 4e-16 Identities = 53/170 (31%), Positives = 89/170 (52%), Gaps = 3/170 (1%) Query: 43 KAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIH 102 K V++G VGK++L Q F E +DPT++++Y K +TL + L+++DTAGQ + Sbjct: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67 Query: 103 RALRDQCLAVCDGVLGVFALDDPSSLIQLQQIWATWGPHPAQ---PLVLVGNKCDLVTTA 159 L + G + V+++ S ++ ++ + P+VLVGNK DL Sbjct: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127 Query: 160 GDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKE 209 LA SWGA F+E+SA+ Q + F+ ++ EI RV+ + +E Sbjct: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQE 177 >gi|5032041 Ras homolog enriched in brain [Homo sapiens] Length = 184 Score = 79.0 bits (193), Expect = 3e-15 Identities = 51/169 (30%), Positives = 89/169 (52%), Gaps = 3/169 (1%) Query: 43 KAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIH 102 K ++G VGKS+LTIQ FV+ +DPTI++++ K +T++ + L ++DTAGQ + Sbjct: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67 Query: 103 RALRDQCLAVCDGVLGVFALDDPSSLIQLQQIWATWGPHPAQ---PLVLVGNKCDLVTTA 159 +G + V+++ S ++ I + P++LVGNK DL Sbjct: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127 Query: 160 GDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAK 208 ++ ALA SW A F+E+SAK Q + F ++ E +++ A ++ Sbjct: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQ 176 >gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sapiens] Length = 205 Score = 77.0 bits (188), Expect = 1e-14 Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 7/169 (4%) Query: 40 PEY----KAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQ-DSYWKELTLDSGDCILNVL 94 PEY K +++G SGVGKS L ++ + E + TI D + + LD L + Sbjct: 6 PEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIW 65 Query: 95 DTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSLIQLQQIWATWGPHPAQPL--VLVGNK 152 DTAGQ R + G++ V+ + D S ++Q + ++ + +LVGNK Sbjct: 66 DTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNK 125 Query: 153 CDLVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQR 201 CDL T + A A S G F+ETSAK VE++F + EI++ Sbjct: 126 CDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKK 174 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.132 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,435,612 Number of Sequences: 37866 Number of extensions: 393927 Number of successful extensions: 1372 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 124 Number of HSP's successfully gapped in prelim test: 65 Number of HSP's that attempted gapping in prelim test: 1092 Number of HSP's gapped (non-prelim): 200 length of query: 233 length of database: 18,247,518 effective HSP length: 99 effective length of query: 134 effective length of database: 14,498,784 effective search space: 1942837056 effective search space used: 1942837056 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.