Search of human proteins with 29788996

Search of human proteins with 29788996

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29788996 paraoxonase 3 [Homo sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29788996 paraoxonase 3 [Homo sapiens]                              712   0.0  
gi|66529294 paraoxonase 2 isoform 1 [Homo sapiens]                    488   e-138
gi|66529396 paraoxonase 2 isoform 2 [Homo sapiens]                    457   e-129
gi|19923106 paraoxonase 1 precursor [Homo sapiens]                    454   e-128
gi|149944516 tet oncogene family member 3 [Homo sapiens]               34   0.23 
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    32   0.66 
gi|16904383 leucine rich repeat containing 7 [Homo sapiens]            32   1.1  
gi|6912580 SAM pointed domain containing ets transcription facto...    30   4.3  
gi|155722985 SMC5 protein [Homo sapiens]                               29   7.3  
gi|25777704 zinc finger 398 isoform a [Homo sapiens]                   28   9.5  
gi|33239445 eukaryotic translation initiation factor 3, subunit ...    28   9.5  
gi|83367072 eukaryotic translation initiation factor 3, subunit ...    28   9.5  

>gi|29788996 paraoxonase 3 [Homo sapiens]
          Length = 354

 Score =  712 bits (1838), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS 60
           MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS
Sbjct: 1   MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS 60

Query: 61  GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI 120
           GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI
Sbjct: 61  GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI 120

Query: 121 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT 180
           DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT
Sbjct: 121 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT 180

Query: 181 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA 240
           RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA
Sbjct: 181 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA 240

Query: 241 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG 300
           AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG
Sbjct: 241 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG 300

Query: 301 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL 354
           SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
Sbjct: 301 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL 354


>gi|66529294 paraoxonase 2 isoform 1 [Homo sapiens]
          Length = 354

 Score =  488 bits (1255), Expect = e-138
 Identities = 232/354 (65%), Positives = 287/354 (81%)

Query: 1   MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS 60
           MG+LVA+ LLG+ L+L+GE  LA R R+ ASREVE V+  +CHLI+ +E+GSEDIDILP+
Sbjct: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60

Query: 61  GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI 120
           GLAF S GLK+PG+ +FAPD+PG I +MDL E+ PRA+ L IS GFD   FNPHGIS FI
Sbjct: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI 120

Query: 121 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT 180
           D D+TVYL+VVNHP  K+TVEIFKFEE + SL++LKT+KHELL SVNDI  +GP  FYAT
Sbjct: 121 DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT 180

Query: 181 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA 240
            DHYF++  L + E  L+L W  V++YSP EVKVVA+GF SANGI +S D KY+YVAD+ 
Sbjct: 181 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL 240

Query: 241 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG 300
           A  IH++EKH N +LTQLKV++L TLVDNL++DP++GDI  GCHPN  KL  Y+P +PP 
Sbjct: 241 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS 300

Query: 301 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL 354
           SEVLRIQN+LSEKP V+TVYANNGSVLQG+SVASVY GK+LIGT++H+ LYCEL
Sbjct: 301 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 354


>gi|66529396 paraoxonase 2 isoform 2 [Homo sapiens]
          Length = 342

 Score =  457 bits (1175), Expect = e-129
 Identities = 222/354 (62%), Positives = 276/354 (77%), Gaps = 12/354 (3%)

Query: 1   MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS 60
           MG+LVA+ LLG+ L+L+GE  LA R R+ ASREVE V+  +CHLI+ +E+GSEDIDILP+
Sbjct: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60

Query: 61  GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI 120
           GLAF S GLK+PG+ +FAPD+PG I +MDL E+ PRA+ L IS GFD   FNPHGIS FI
Sbjct: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI 120

Query: 121 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT 180
           D +             K+TVEIFKFEE + SL++LKT+KHELL SVNDI  +GP  FYAT
Sbjct: 121 DNE------------FKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT 168

Query: 181 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA 240
            DHYF++  L + E  L+L W  V++YSP EVKVVA+GF SANGI +S D KY+YVAD+ 
Sbjct: 169 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL 228

Query: 241 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG 300
           A  IH++EKH N +LTQLKV++L TLVDNL++DP++GDI  GCHPN  KL  Y+P +PP 
Sbjct: 229 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS 288

Query: 301 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL 354
           SEVLRIQN+LSEKP V+TVYANNGSVLQG+SVASVY GK+LIGT++H+ LYCEL
Sbjct: 289 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 342


>gi|19923106 paraoxonase 1 precursor [Homo sapiens]
          Length = 355

 Score =  454 bits (1168), Expect = e-128
 Identities = 216/355 (60%), Positives = 280/355 (78%), Gaps = 1/355 (0%)

Query: 1   MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS 60
           M KL+AL LLG+GL+L      +++ R+NA REV+PVE  NC+L++ +E+GSED++ILP+
Sbjct: 1   MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN 60

Query: 61  GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGG-FDKELFNPHGISIF 119
           GLAFISSGLKYPG+ +F P+ PGKI LMDLNE++P    L I+G  FD   FNPHGIS F
Sbjct: 61  GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF 120

Query: 120 IDKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYA 179
            D+DN +YL VVNHP  KSTVE+FKF+E+++SL++LKTI+H+LL ++NDIV +GPE FY 
Sbjct: 121 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG 180

Query: 180 TRDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADV 239
           T DHYF +  L  +EM L L W+YV++YSP EV+VVA+GF  ANGI +S D KYVY+A++
Sbjct: 181 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL 240

Query: 240 AAKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPP 299
            A  IH+ EKH NW LT LK +   TLVDN++VDP TGD+  GCHPN MK+  Y+ E+PP
Sbjct: 241 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP 300

Query: 300 GSEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL 354
            SEVLRIQN+L+E+P+V+ VYA NG+VLQG++VASVY GK+LIGTVFHK LYCEL
Sbjct: 301 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL 355


>gi|149944516 tet oncogene family member 3 [Homo sapiens]
          Length = 1660

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 16/81 (19%)

Query: 25  RERVNASREVEPVEPENCHLIEELESGSEDIDILPSGLAFISSGLKYPGMPNFAPDEP-- 82
           RE  N SR   P  PE C       +GSED+D L + LA    G+K P      P+ P  
Sbjct: 95  REAGNNSRGPRP-GPEGC------SAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDY 147

Query: 83  -----GKI--FLMDLNEQNPR 96
                GKI   +M+  E+ PR
Sbjct: 148 LEWLEGKIKSVVMEGGEERPR 168


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 32.3 bits (72), Expect = 0.66
 Identities = 21/65 (32%), Positives = 28/65 (43%)

Query: 18  GEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPSGLAFISSGLKYPGMPNF 77
           G  +  FRE    SR   P+ PE     EE +    ++D   S L F  S  +Y G P F
Sbjct: 211 GRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSKDRYGGQPLF 270

Query: 78  APDEP 82
           +   P
Sbjct: 271 SEKFP 275


>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
          Length = 1537

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 25/121 (20%), Positives = 53/121 (43%), Gaps = 4/121 (3%)

Query: 41  NCHLIEELESGSEDIDILPSGLAFISSGLKYPGMPNFAPDEPGKI-FLMDLNEQNPRAQA 99
           N  L+EE +    +++ LPS + ++ S        NF P+ P +I    ++   + R+  
Sbjct: 297 NLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 356

Query: 100 LEISGGFDKELFNPHGISIFIDKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIK 159
           LE      +E+     + +    DN +     +   +K    ++  + Q ++L+ L+T  
Sbjct: 357 LEF---LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEA 413

Query: 160 H 160
           H
Sbjct: 414 H 414


>gi|6912580 SAM pointed domain containing ets transcription factor
           [Homo sapiens]
          Length = 335

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 14/41 (34%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 30  ASREVEPVEPENCHLIEELESGSEDIDILPSGLAFISSGLK 70
           +SRE  P EPE C +I+  ++ +  +D++P GL      L+
Sbjct: 81  SSREEPPEEPEQCPVIDS-QAPAGSLDLVPGGLTLEEHSLE 120


>gi|155722985 SMC5 protein [Homo sapiens]
          Length = 1101

 Score = 28.9 bits (63), Expect = 7.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 122 KDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYATR 181
           KDN    Y+ NH    + +  F FE Q+   V+LK ++      VN   V+ P+  YA +
Sbjct: 492 KDNKNAKYIENHIP-SNDLRAFVFESQEDMEVFLKEVRDNKKLRVN--AVIAPKSSYADK 548


>gi|25777704 zinc finger 398 isoform a [Homo sapiens]
          Length = 642

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 6/73 (8%)

Query: 248 EKHDNWDLTQLKVIQLGTLVDNLTVDPATG--DILAGCHPNPMKLLNYNPEDPPGSEVLR 305
           EK + W     K I  G     +++D A    D+L+   P       +N ED  G E   
Sbjct: 158 EKLEEWQKELYKNIMKGNYESLISMDYAINQPDVLSQIQPEG----EHNTEDQAGPEESE 213

Query: 306 IQNVLSEKPRVST 318
           I    SE+P +ST
Sbjct: 214 IPTDPSEEPGIST 226


>gi|33239445 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 183 HYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVAAK 242
           H   N  +   +M  D +    +F+SP+   VV  G  S NG     D     V ++A  
Sbjct: 593 HVKNNGKIELIKMF-DKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAE- 650

Query: 243 NIHIMEKHDNWDLTQLKVI 261
             H M     WD T   V+
Sbjct: 651 --HYMASDVEWDPTGRYVV 667


>gi|83367072 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 183 HYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVAAK 242
           H   N  +   +M  D +    +F+SP+   VV  G  S NG     D     V ++A  
Sbjct: 593 HVKNNGKIELIKMF-DKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAE- 650

Query: 243 NIHIMEKHDNWDLTQLKVI 261
             H M     WD T   V+
Sbjct: 651 --HYMASDVEWDPTGRYVV 667


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,279,246
Number of Sequences: 37866
Number of extensions: 592946
Number of successful extensions: 1384
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1377
Number of HSP's gapped (non-prelim): 12
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.