Guide to the Human Genome
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Search of human proteins with 29570798

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29570798 phosphoribosyl pyrophosphate amidotransferase
proprotein [Homo sapiens]
         (517 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29570798 phosphoribosyl pyrophosphate amidotransferase propro...  1046   0.0  
gi|4826742 glutamine-fructose-6-phosphate transaminase 2 [Homo s...    62   2e-09
gi|205277386 glucosamine-fructose-6-phosphate aminotransferase [...    57   3e-08
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso...    32   1.1  
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso...    32   1.1  
gi|4504483 hypoxanthine phosphoribosyltransferase 1 [Homo sapiens]     31   2.4  
gi|24041029 nitric oxide synthase 2A [Homo sapiens]                    31   3.1  
gi|134142824 forkhead box D2 [Homo sapiens]                            31   3.1  
gi|83367077 mucin 16 [Homo sapiens]                                    30   5.3  
gi|4504223 glucuronidase, beta [Homo sapiens]                          30   5.3  
gi|6005747 ring finger protein 2 [Homo sapiens]                        29   9.0  
gi|241982802 HMG box domain containing 3 [Homo sapiens]                29   9.0  

>gi|29570798 phosphoribosyl pyrophosphate amidotransferase
           proprotein [Homo sapiens]
          Length = 517

 Score = 1046 bits (2704), Expect = 0.0
 Identities = 517/517 (100%), Positives = 517/517 (100%)

Query: 1   MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT 60
           MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT
Sbjct: 1   MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT 60

Query: 61  FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA 120
           FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA
Sbjct: 61  FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA 120

Query: 121 HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA 180
           HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA
Sbjct: 121 HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA 180

Query: 181 PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL 240
           PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL
Sbjct: 181 PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL 240

Query: 241 SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY 300
           SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY
Sbjct: 241 SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY 300

Query: 301 TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP 360
           TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP
Sbjct: 301 TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP 360

Query: 361 NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP 420
           NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP
Sbjct: 361 NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP 420

Query: 421 PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE 480
           PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE
Sbjct: 421 PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE 480

Query: 481 KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW 517
           KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
Sbjct: 481 KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW 517


>gi|4826742 glutamine-fructose-6-phosphate transaminase 2 [Homo
           sapiens]
          Length = 682

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 47/186 (25%), Positives = 88/186 (47%), Gaps = 12/186 (6%)

Query: 12  CGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSH------- 64
           CG+F  +      T+ ++   +  GL  L++RG +SAG+   DG++    + H       
Sbjct: 2   CGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAI-DGNNHEVKERHIQLVKKR 60

Query: 65  -KGMGLVNHVFTEDN--LKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAH 121
            K   L   ++ +D+  LK  + ++ GI HTR+AT G     N  P   +    +  V H
Sbjct: 61  GKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDK-GNEFVVIH 119

Query: 122 NGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAP 181
           NG + N   LRK L   G    + +D+E I +L+ Y     + +   +   ++ ++++  
Sbjct: 120 NGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLE 179

Query: 182 TAYSLL 187
            A++L+
Sbjct: 180 GAFALV 185


>gi|205277386 glucosamine-fructose-6-phosphate aminotransferase
           [Homo sapiens]
          Length = 681

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 47/189 (24%), Positives = 88/189 (46%), Gaps = 15/189 (7%)

Query: 12  CGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSH------- 64
           CG+F  +      T+ ++   +  GL  L++RG +SAG V  DG +   ++++       
Sbjct: 2   CGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAG-VGFDGGNDKDWEANACKIQLI 60

Query: 65  KGMGLVN------HVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIA 118
           K  G V       H   + +L   +  +LGI HTR+AT G+    N  P   +  + +  
Sbjct: 61  KKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDK-NNEFI 119

Query: 119 VAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMK 178
           V HNG + N   L+K L   G    + +D+E I +L+ Y     +     +   ++ +++
Sbjct: 120 VIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQ 179

Query: 179 EAPTAYSLL 187
           +   A++L+
Sbjct: 180 QLEGAFALV 188


>gi|225543215 antigen identified by monoclonal antibody Ki-67 isoform
            2 [Homo sapiens]
          Length = 2896

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 32/135 (23%), Positives = 52/135 (38%), Gaps = 21/135 (15%)

Query: 33   ITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHT 92
            I+LG VG++        +  + G +  T +   G G     F E   + L  +N G G  
Sbjct: 1641 ISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGME 1700

Query: 93   RYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMIT 152
            R+  T K E ++     +E L G                 K+L +       S+  +  T
Sbjct: 1701 RWPRTPKEEAQS-----LEDLAG----------------FKELFQTPDHTEESTTDDKTT 1739

Query: 153  QLLAYTPPQEQDDTP 167
            ++   +PP E  DTP
Sbjct: 1740 KIACKSPPPESMDTP 1754


>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
            1 [Homo sapiens]
          Length = 3256

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 32/135 (23%), Positives = 52/135 (38%), Gaps = 21/135 (15%)

Query: 33   ITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHT 92
            I+LG VG++        +  + G +  T +   G G     F E   + L  +N G G  
Sbjct: 2001 ISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGME 2060

Query: 93   RYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMIT 152
            R+  T K E ++     +E L G                 K+L +       S+  +  T
Sbjct: 2061 RWPRTPKEEAQS-----LEDLAG----------------FKELFQTPDHTEESTTDDKTT 2099

Query: 153  QLLAYTPPQEQDDTP 167
            ++   +PP E  DTP
Sbjct: 2100 KIACKSPPPESMDTP 2114


>gi|4504483 hypoxanthine phosphoribosyltransferase 1 [Homo sapiens]
          Length = 218

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 10/62 (16%)

Query: 382 GKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIK--------YPCFMGINIP 433
           GK +++V+D I  G T+  ++ L+++   K V  +VAS  +K         P F+G  IP
Sbjct: 127 GKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMV--KVASLLVKRTPRSVGYKPDFVGFEIP 184

Query: 434 TK 435
            K
Sbjct: 185 DK 186


>gi|24041029 nitric oxide synthase 2A [Homo sapiens]
          Length = 1153

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 13/42 (30%), Positives = 25/42 (59%)

Query: 170 VARIKNLMKEAPTAYSLLIMHRDVIYAVRDPYGNRPLCIGRL 211
           +AR++ + KE  T  +  +   ++I+A +  + N P CIGR+
Sbjct: 163 LARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRI 204


>gi|134142824 forkhead box D2 [Homo sapiens]
          Length = 495

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 11/84 (13%)

Query: 196 AVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEI 255
           A R P    P     LI ++ +   +K+       +  SE C F+S    YYRE  P   
Sbjct: 120 ATRSPLVKPPYSYIALITMAILQSPKKR-------LTLSEICEFISGRFPYYREKFPAWQ 172

Query: 256 VEISRHNVQTLDI---ISRSEGNP 276
             I RHN+   D    I R  GNP
Sbjct: 173 NSI-RHNLSLNDCFVKIPREPGNP 195


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 20/55 (36%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 210  RLIPVSDINDKEK-----KTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEIS 259
            R+ P     DKE       T ET GWV SSE  S  +I A      L   +V  S
Sbjct: 3931 RIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTS 3985


>gi|4504223 glucuronidase, beta [Homo sapiens]
          Length = 651

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 335 YAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKF 373
           YA   G PYV+V+C N Y        ++ L QL +A +F
Sbjct: 487 YAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQF 525


>gi|6005747 ring finger protein 2 [Homo sapiens]
          Length = 336

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 7/76 (9%)

Query: 437 ELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKK----QKEKKHDIMIQENGN 492
           ++  ++ E++   E + A    + + + L  S++EG+K +     Q+ KK  I   ENG+
Sbjct: 112 KIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQI---ENGS 168

Query: 493 GLECFEKSGHCTACLT 508
           G E    S HC+   T
Sbjct: 169 GAEDNGDSSHCSNAST 184


>gi|241982802 HMG box domain containing 3 [Homo sapiens]
          Length = 1292

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 144 TSSDSEMITQLLAYTPPQEQDDTPDW----VARIKNLMKEAP 181
           T  +SE ++QLL   PP+E  +  +W    ++    L+KEAP
Sbjct: 390 TLENSEAVSQLLNVAPPREVGEESEWEEVIISDAHVLVKEAP 431


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,039,246
Number of Sequences: 37866
Number of extensions: 887950
Number of successful extensions: 1867
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1850
Number of HSP's gapped (non-prelim): 18
length of query: 517
length of database: 18,247,518
effective HSP length: 107
effective length of query: 410
effective length of database: 14,195,856
effective search space: 5820300960
effective search space used: 5820300960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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