Guide to the Human Genome
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Search of human proteins with 122937384

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937384 transmembrane protein 218 [Homo sapiens]
         (115 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937384 transmembrane protein 218 [Homo sapiens]                 223   3e-59
gi|40316941 androgen-induced 1 [Homo sapiens]                          30   0.31 
gi|7705636 golgi transport 1 homolog B [Homo sapiens]                  30   0.41 
gi|196123591 cytochrome b [Homo sapiens neanderthalensis]              27   2.7  
gi|239757849 PREDICTED: hypothetical protein [Homo sapiens]            27   2.7  
gi|239752365 PREDICTED: hypothetical protein XP_002348214 [Homo ...    27   2.7  
gi|239746879 PREDICTED: hypothetical protein XP_002343873 [Homo ...    27   2.7  
gi|10947061 adenylate cyclase 6 isoform b [Homo sapiens]               27   2.7  
gi|148612887 choline transporter-like protein 4 [Homo sapiens]         27   2.7  
gi|251831119 cytochrome b [Homo sapiens]                               27   4.5  
gi|40254478 excitatory amino acid transporter 2 [Homo sapiens]         27   4.5  
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]                26   5.9  
gi|117553619 solute carrier family 39, member 7 [Homo sapiens]         26   5.9  
gi|117553608 solute carrier family 39, member 7 [Homo sapiens]         26   5.9  
gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 is...    26   5.9  
gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 is...    26   5.9  
gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 is...    26   5.9  
gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 is...    26   5.9  
gi|10181096 adenylate cyclase 6 isoform a [Homo sapiens]               26   7.7  
gi|52353342 olfactory receptor, family 6, subfamily K, member 6 ...    26   7.7  

>gi|122937384 transmembrane protein 218 [Homo sapiens]
          Length = 115

 Score =  223 bits (568), Expect = 3e-59
 Identities = 115/115 (100%), Positives = 115/115 (100%)

Query: 1   MAGTVLGVGAGVFILALLWVAVLLLCVLLSRASGAARFSVIFLFFGAVIITSVLLLFPRA 60
           MAGTVLGVGAGVFILALLWVAVLLLCVLLSRASGAARFSVIFLFFGAVIITSVLLLFPRA
Sbjct: 1   MAGTVLGVGAGVFILALLWVAVLLLCVLLSRASGAARFSVIFLFFGAVIITSVLLLFPRA 60

Query: 61  GEFPAPEVEVKIVDDFFIGRYVLLAFLSAIFLGGLFLVLIHYVLEPIYAKPLHSY 115
           GEFPAPEVEVKIVDDFFIGRYVLLAFLSAIFLGGLFLVLIHYVLEPIYAKPLHSY
Sbjct: 61  GEFPAPEVEVKIVDDFFIGRYVLLAFLSAIFLGGLFLVLIHYVLEPIYAKPLHSY 115


>gi|40316941 androgen-induced 1 [Homo sapiens]
          Length = 238

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 19/73 (26%), Positives = 34/73 (46%)

Query: 43  LFFGAVIITSVLLLFPRAGEFPAPEVEVKIVDDFFIGRYVLLAFLSAIFLGGLFLVLIHY 102
           +FFG  ++T +  L  R       E ++K +         +LAF   +F+  +F ++  Y
Sbjct: 52  VFFGICVLTDLSSLLTRGSGNQEQERQLKKLISLRDWMLAVLAFPVGVFVVAVFWIIYAY 111

Query: 103 VLEPIYAKPLHSY 115
             E IY K L ++
Sbjct: 112 DREMIYPKLLDNF 124


>gi|7705636 golgi transport 1 homolog B [Homo sapiens]
          Length = 138

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 34  GAARFSVIFLFFGAVIITSVLLLFPRAGEFPAP---EVEVKIVDDFFIGRYVLLAFLSAI 90
           G   F V FLFFG ++     LL      F A     + ++    FF  ++ + A  +  
Sbjct: 13  GLTGFGVFFLFFGMILFFDKALLAIGNVLFVAGLAFVIGLERTFRFFFQKHKMKA--TGF 70

Query: 91  FLGGLFLVLIHYVL 104
           FLGG+F+VLI + L
Sbjct: 71  FLGGVFVVLIGWPL 84


>gi|196123591 cytochrome b [Homo sapiens neanderthalensis]
          Length = 378

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 14/108 (12%)

Query: 6   LGVGAGVFILALLWVAVLLLCVLLSRASGAARFSVIFL------FFGAVIITSVLLLFPR 59
           L +G G++  + L+     + ++L  A+ A  F    L      F+GA +IT++L   P 
Sbjct: 96  LHIGRGLYYGSFLYSKTWNIGIILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPY 155

Query: 60  AGE------FPAPEVEVKIVDDFFIGRYVLLAFLSAIFLGGLFLVLIH 101
            G       +    V+   +  FF   ++L   ++A  L  L L+ +H
Sbjct: 156 IGTDLVQWIWGGYSVDSPTLTRFFTFHFILPFIIAA--LAALHLLFLH 201


>gi|239757849 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 183

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/31 (48%), Positives = 21/31 (67%)

Query: 83  LLAFLSAIFLGGLFLVLIHYVLEPIYAKPLH 113
           LL FLSA+FL  L L+ +++VLE  +A   H
Sbjct: 45  LLLFLSALFLPQLRLLRLYWVLEFSFAGSPH 75


>gi|239752365 PREDICTED: hypothetical protein XP_002348214 [Homo
           sapiens]
          Length = 183

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/31 (48%), Positives = 21/31 (67%)

Query: 83  LLAFLSAIFLGGLFLVLIHYVLEPIYAKPLH 113
           LL FLSA+FL  L L+ +++VLE  +A   H
Sbjct: 45  LLLFLSALFLPQLRLLRLYWVLEFSFAGSPH 75


>gi|239746879 PREDICTED: hypothetical protein XP_002343873 [Homo
           sapiens]
          Length = 183

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/31 (48%), Positives = 21/31 (67%)

Query: 83  LLAFLSAIFLGGLFLVLIHYVLEPIYAKPLH 113
           LL FLSA+FL  L L+ +++VLE  +A   H
Sbjct: 45  LLLFLSALFLPQLRLLRLYWVLEFSFAGSPH 75


>gi|10947061 adenylate cyclase 6 isoform b [Homo sapiens]
          Length = 1115

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 22/96 (22%)

Query: 5   VLGVGAGVFILALLWVAVLLLCVLLSRAS----GAARFSVIFL----FFGAVIITSVLLL 56
           +LG+ A +F+L L+ V   L+C + S  S       R S   +       AV I SVLL+
Sbjct: 697 MLGIYASIFLLLLITV---LICAVYSCGSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLV 753

Query: 57  FPRAGEFPAPEVEVKIVDDFFIGRYVLLAFLSAIFL 92
           F  A           I + +FIG  +L    S++FL
Sbjct: 754 FTSA-----------IANMYFIGNMLLSLLASSVFL 778



 Score = 25.8 bits (55), Expect = 7.7
 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 36/105 (34%)

Query: 39  SVIFLFFGAVIITSVLLLFPRAGEFPAPE------------VEVKIV--------DDFFI 78
           S+  L    V++T+VLL F  A   P P             V + +V        D  ++
Sbjct: 151 SLTLLMAVLVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWV 210

Query: 79  GRYVLLAFLSAIFLGG----------------LFLVLIHYVLEPI 107
             YV+L  L+A+ +GG                +F V I Y L PI
Sbjct: 211 VSYVVLGILAAVQVGGALAADPRSPSAGLWCPVFFVYIAYTLLPI 255


>gi|148612887 choline transporter-like protein 4 [Homo sapiens]
          Length = 710

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 65  APEVEVKIVDDFFIGRY-VLLAFLSAIFLGGLFLVLIHYVLEPI 107
           A ++ VKI +DF    Y +L+A   A+ L  LF++L+  V  P+
Sbjct: 214 ARDISVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAGPL 257


>gi|251831119 cytochrome b [Homo sapiens]
          Length = 380

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 14/108 (12%)

Query: 6   LGVGAGVFILALLWVAVLLLCVLLSRASGAARFSVIFL------FFGAVIITSVLLLFPR 59
           L +G G++  + L+     + ++L  A+ A  F    L      F+GA +IT++L   P 
Sbjct: 96  LHIGRGLYYGSFLYSETWNIGIILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPY 155

Query: 60  AGE------FPAPEVEVKIVDDFFIGRYVLLAFLSAIFLGGLFLVLIH 101
            G       +    V+   +  FF   ++L   ++A  L  L L+ +H
Sbjct: 156 IGTDLVQWIWGGYSVDSPTLTRFFTFHFILPFIIAA--LATLHLLFLH 201


>gi|40254478 excitatory amino acid transporter 2 [Homo sapiens]
          Length = 574

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 10/27 (37%), Positives = 18/27 (66%)

Query: 78  IGRYVLLAFLSAIFLGGLFLVLIHYVL 104
           +G Y++   +  I  GG+FL LI++V+
Sbjct: 313 LGMYMVTVIIGLIIHGGIFLPLIYFVV 339


>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
          Length = 419

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/47 (34%), Positives = 22/47 (46%)

Query: 61  GEFPAPEVEVKIVDDFFIGRYVLLAFLSAIFLGGLFLVLIHYVLEPI 107
           G+F   EVEVK + DF      + AF+S      L +    Y  EP+
Sbjct: 277 GKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPV 323


>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
          Length = 469

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 13/25 (52%), Positives = 16/25 (64%)

Query: 82  VLLAFLSAIFLGGLFLVLIHYVLEP 106
           +LL+F S   LG  FL LI + LEP
Sbjct: 171 ILLSFASGGLLGDAFLHLIPHALEP 195


>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
          Length = 469

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 13/25 (52%), Positives = 16/25 (64%)

Query: 82  VLLAFLSAIFLGGLFLVLIHYVLEP 106
           +LL+F S   LG  FL LI + LEP
Sbjct: 171 ILLSFASGGLLGDAFLHLIPHALEP 195


>gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform b [Homo sapiens]
          Length = 341

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 15/100 (15%)

Query: 6   LGVGAGVFILALLWVAVLLLCVLLS-------RASGAARFSVI----FLFFGAVIITSVL 54
           L  G  V    L W+ +L L V +S       RA      S++    ++FF   ++T   
Sbjct: 187 LFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSA 246

Query: 55  LLFPRAGEFPAPEVEVKIVDDFF---IGRYVLLAFLSAIF 91
           +LF    + P  +V +  +  FF   +G ++L AF    F
Sbjct: 247 ILFKEWQDMPVDDV-IGTLSGFFTIIVGIFLLHAFKDVSF 285


>gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 15/100 (15%)

Query: 6   LGVGAGVFILALLWVAVLLLCVLLS-------RASGAARFSVI----FLFFGAVIITSVL 54
           L  G  V    L W+ +L L V +S       RA      S++    ++FF   ++T   
Sbjct: 206 LFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSA 265

Query: 55  LLFPRAGEFPAPEVEVKIVDDFF---IGRYVLLAFLSAIF 91
           +LF    + P  +V +  +  FF   +G ++L AF    F
Sbjct: 266 ILFKEWQDMPVDDV-IGTLSGFFTIIVGIFLLHAFKDVSF 304


>gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 15/100 (15%)

Query: 6   LGVGAGVFILALLWVAVLLLCVLLS-------RASGAARFSVI----FLFFGAVIITSVL 54
           L  G  V    L W+ +L L V +S       RA      S++    ++FF   ++T   
Sbjct: 206 LFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSA 265

Query: 55  LLFPRAGEFPAPEVEVKIVDDFF---IGRYVLLAFLSAIF 91
           +LF    + P  +V +  +  FF   +G ++L AF    F
Sbjct: 266 ILFKEWQDMPVDDV-IGTLSGFFTIIVGIFLLHAFKDVSF 304


>gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 15/100 (15%)

Query: 6   LGVGAGVFILALLWVAVLLLCVLLS-------RASGAARFSVI----FLFFGAVIITSVL 54
           L  G  V    L W+ +L L V +S       RA      S++    ++FF   ++T   
Sbjct: 206 LFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSA 265

Query: 55  LLFPRAGEFPAPEVEVKIVDDFF---IGRYVLLAFLSAIF 91
           +LF    + P  +V +  +  FF   +G ++L AF    F
Sbjct: 266 ILFKEWQDMPVDDV-IGTLSGFFTIIVGIFLLHAFKDVSF 304


>gi|10181096 adenylate cyclase 6 isoform a [Homo sapiens]
          Length = 1168

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 36/105 (34%)

Query: 39  SVIFLFFGAVIITSVLLLFPRAGEFPAPE------------VEVKIV--------DDFFI 78
           S+  L    V++T+VLL F  A   P P             V + +V        D  ++
Sbjct: 151 SLTLLMAVLVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWV 210

Query: 79  GRYVLLAFLSAIFLGG----------------LFLVLIHYVLEPI 107
             YV+L  L+A+ +GG                +F V I Y L PI
Sbjct: 211 VSYVVLGILAAVQVGGALAADPRSPSAGLWCPVFFVYIAYTLLPI 255


>gi|52353342 olfactory receptor, family 6, subfamily K, member 6
           [Homo sapiens]
          Length = 343

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 8/49 (16%)

Query: 10  AGVFILALLWVAVLLLCVLLSRASG--------AARFSVIFLFFGAVII 50
           A   ++AL ++ ++++ + +  A G        AA  +V  LFFG+V +
Sbjct: 236 ASFLVIALSYIRIIIVILGMHSAEGHHKAFSTCAAHLAVFLLFFGSVAV 284


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.336    0.152    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,695,078
Number of Sequences: 37866
Number of extensions: 129344
Number of successful extensions: 697
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 679
Number of HSP's gapped (non-prelim): 30
length of query: 115
length of database: 18,247,518
effective HSP length: 85
effective length of query: 30
effective length of database: 15,028,908
effective search space: 450867240
effective search space used: 450867240
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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