Search of human proteins with 12232475

Search of human proteins with 12232475

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]
         (621 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]           1264   0.0  
gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]            606   e-173
gi|4501893 actinin, alpha 2 [Homo sapiens]                             33   0.78 
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    31   3.9  
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]     30   5.1  
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]     30   5.1  
gi|31377705 centrosomal protein 97kDa [Homo sapiens]                   30   5.1  
gi|170014684 IQ motif containing B1 isoform a [Homo sapiens]           30   6.6  
gi|4502027 albumin preproprotein [Homo sapiens]                        30   8.6  
gi|50540545 Barkor [Homo sapiens]                                      30   8.6  
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]     30   8.6  
gi|29029550 cat eye syndrome critical region protein 1 isoform a...    30   8.6  

>gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]
          Length = 621

 Score = 1264 bits (3272), Expect = 0.0
 Identities = 621/621 (100%), Positives = 621/621 (100%)

Query: 1   MTKAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKF 60
           MTKAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKF
Sbjct: 1   MTKAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKF 60

Query: 61  LRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDG 120
           LRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDG
Sbjct: 61  LRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDG 120

Query: 121 NSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLE 180
           NSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLE
Sbjct: 121 NSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLE 180

Query: 181 NFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDAN 240
           NFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDAN
Sbjct: 181 NFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDAN 240

Query: 241 VNVIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFPMIEQ 300
           VNVIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFPMIEQ
Sbjct: 241 VNVIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFPMIEQ 300

Query: 301 LSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRKKWAQ 360
           LSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRKKWAQ
Sbjct: 301 LSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRKKWAQ 360

Query: 361 EPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNLTVDM 420
           EPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNLTVDM
Sbjct: 361 EPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNLTVDM 420

Query: 421 LIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDVVGYF 480
           LIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDVVGYF
Sbjct: 421 LIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDVVGYF 480

Query: 481 SIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKE 540
           SIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKE
Sbjct: 481 SIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKE 540

Query: 541 RKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLENNRRGS 600
           RKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLENNRRGS
Sbjct: 541 RKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLENNRRGS 600

Query: 601 PGGPHDLCSPSLHHPSRNIST 621
           PGGPHDLCSPSLHHPSRNIST
Sbjct: 601 PGGPHDLCSPSLHHPSRNIST 621


>gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]
          Length = 1027

 Score =  606 bits (1562), Expect = e-173
 Identities = 298/301 (99%), Positives = 299/301 (99%)

Query: 297 MIEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRK 356
           MIEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRK
Sbjct: 636 MIEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRK 695

Query: 357 KWAQEPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNL 416
           KWAQEPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNL
Sbjct: 696 KWAQEPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNL 755

Query: 417 TVDMLIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDV 476
           TVDMLIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDV
Sbjct: 756 TVDMLIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDV 815

Query: 477 VGYFSIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRF 536
           VGYFSIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRF
Sbjct: 816 VGYFSIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRF 875

Query: 537 VPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLENN 596
           VPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLE  
Sbjct: 876 VPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLEER 935

Query: 597 R 597
           +
Sbjct: 936 Q 936



 Score =  600 bits (1546), Expect = e-171
 Identities = 294/294 (100%), Positives = 294/294 (100%)

Query: 3   KAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKFLR 62
           KAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKFLR
Sbjct: 251 KAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKFLR 310

Query: 63  NYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDGNS 122
           NYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDGNS
Sbjct: 311 NYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDGNS 370

Query: 123 EAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLENF 182
           EAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLENF
Sbjct: 371 EAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLENF 430

Query: 183 RIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDANVN 242
           RIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDANVN
Sbjct: 431 RIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDANVN 490

Query: 243 VIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFP 296
           VIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFP
Sbjct: 491 VIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFP 544


>gi|4501893 actinin, alpha 2 [Homo sapiens]
          Length = 894

 Score = 33.1 bits (74), Expect = 0.78
 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 20/117 (17%)

Query: 279 DLQDRFKIITPEAVNIFPMIEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKC 338
           DLQD F         I   IE++  LIT H Q +  L + D E +       ++   ++ 
Sbjct: 538 DLQDMF---------IVHSIEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQS 588

Query: 339 YKWVLKESSRYG---LEDWRKKWAQEPALVKI-----SEELAGILAQHAQPVNEKRF 387
           Y   +  S+ Y    +++ R KW +   LV I      EELA    QHA     ++F
Sbjct: 589 YNIRISSSNPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELA---RQHANERLRRQF 642


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 124  AAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKK 169
            AA  IQ TW+ YK +     +++++ A+ +I +A + +  K RL+K
Sbjct: 1269 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRK 1314


>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
          Length = 593

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 157 AWLLYCHKTRLKKILKESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVR 216
           A+++YCHK   K+ ++E     L N+ IR   L      +   R  I  IP +   + + 
Sbjct: 114 AFVMYCHKHEAKRAVRE-----LNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEIL 168

Query: 217 EHIA 220
           E IA
Sbjct: 169 EEIA 172


>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
          Length = 524

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 157 AWLLYCHKTRLKKILKESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVR 216
           A+++YCHK   K+ ++E     L N+ IR   L      +   R  I  IP +   + + 
Sbjct: 114 AFVMYCHKHEAKRAVRE-----LNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEIL 168

Query: 217 EHIA 220
           E IA
Sbjct: 169 EEIA 172


>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
          Length = 865

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 15/77 (19%), Positives = 40/77 (51%), Gaps = 1/77 (1%)

Query: 122 SEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLEN 181
           ++AA K+QA W+ + AR +    +  ++   +  +   + C    ++++ KE  +  ++ 
Sbjct: 559 NDAATKLQACWRGFYARNYNPQAKDVRYEIRLRRMQEHIVCLTDEIRRLRKERDEERIKK 618

Query: 182 FRIRAKHLAANWNRIRT 198
           F ++ +     WN++R+
Sbjct: 619 F-VQEEAFRFLWNQVRS 634


>gi|170014684 IQ motif containing B1 isoform a [Homo sapiens]
          Length = 598

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 9/96 (9%)

Query: 123 EAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLENF 182
           +AA  IQA WK ++ RK     R +K  S VIA+         R K +L+ +RQ+  E+ 
Sbjct: 296 QAACLIQAYWKGFQTRK-----RLKKLPSAVIALQRSF--RSKRSKMLLEINRQKEEEDL 348

Query: 183 RIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREH 218
           +++ +        +R SR   + +  + +   V +H
Sbjct: 349 KLQLQ--LQRQRAMRLSRELQLSMLEIVHPGQVEKH 382


>gi|4502027 albumin preproprotein [Homo sapiens]
          Length = 609

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 1/75 (1%)

Query: 362 PALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVI-EAFPPADNVTNLTVDM 420
           P LV++S  L  + ++  +    KR P    +L   L+Q  V+ E  P +D VT    + 
Sbjct: 445 PTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES 504

Query: 421 LIEPNGKISVLSTGD 435
           L+      S L   +
Sbjct: 505 LVNRRPCFSALEVDE 519


>gi|50540545 Barkor [Homo sapiens]
          Length = 492

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 22/96 (22%)

Query: 215 VREHIADFNTQQNMQLGRLCD-----------ILDANVNVIYIC-SHHMN-DEL------ 255
           +  HI D N  + +     C            +   N N++Y+C S H+N D+L      
Sbjct: 316 ILSHILDVNLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTL 375

Query: 256 --VLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITP 289
             ++Y     S H   +SG  E R+DL++  + + P
Sbjct: 376 RNLMYLVSPSSEHLG-RSGPFEVRADLEESMEFVDP 410


>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
          Length = 405

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 435 DQLHAESPFISSGTTVPQTSVDPQ-VLTYLCLQIGKACRMRDVVGYFS 481
           D++H  SP +++G  V   S + +   T  C+Q+    R RD+  +FS
Sbjct: 106 DRVHYRSPPLATGEPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 153


>gi|29029550 cat eye syndrome critical region protein 1 isoform a
           precursor [Homo sapiens]
          Length = 511

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 19/72 (26%), Positives = 29/72 (40%), Gaps = 7/72 (9%)

Query: 337 KCYKWVLKESSRYGLEDWRKKWAQEPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQT 396
           KC KW+L       LED+RK+                ++ QH + +   +   W KF   
Sbjct: 158 KCSKWIL-------LEDYRKRVQNVTEFDDSLLRNFTLVTQHPEVIYTNQNVVWSKFETI 210

Query: 397 FLSQGGVIEAFP 408
           F +  G+I   P
Sbjct: 211 FFTISGLIHYAP 222


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,567,204
Number of Sequences: 37866
Number of extensions: 1020058
Number of successful extensions: 2231
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2218
Number of HSP's gapped (non-prelim): 21
length of query: 621
length of database: 18,247,518
effective HSP length: 108
effective length of query: 513
effective length of database: 14,157,990
effective search space: 7263048870
effective search space used: 7263048870
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.