Search of human proteins with 28416933

Search of human proteins with 28416933

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
         (422 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]         865   0.0  
gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]         795   0.0  
gi|28416927 purinergic receptor P2X4 [Homo sapiens]                   370   e-102
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]         365   e-101
gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]        341   6e-94
gi|4505545 purinergic receptor P2X1 [Homo sapiens]                    310   1e-84
gi|28416925 purinergic receptor P2X3 [Homo sapiens]                   308   8e-84
gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]         305   5e-83
gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]        303   1e-82
gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]         303   2e-82
gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]         295   5e-80
gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]          274   1e-73
gi|29294631 purinergic receptor P2X7 [Homo sapiens]                   219   5e-57
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]         212   6e-55
gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]         194   2e-49
gi|170763517 transforming, acidic coiled-coil containing protein...    34   0.22 
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]               32   1.1  
gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]    30   5.4  
gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]           30   5.4  
gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]           30   5.4  
gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo ...    30   5.4  
gi|116089333 kelch domain containing 7A [Homo sapiens]                 30   5.4  
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...    29   7.0  
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             29   7.0  
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             29   7.0  
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]           29   9.2  
gi|33859793 hypothetical protein LOC139212 [Homo sapiens]              29   9.2  

>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
          Length = 422

 Score =  865 bits (2234), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60
           MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
Sbjct: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60

Query: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 120
           SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
Sbjct: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 120

Query: 121 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 180
           NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
Sbjct: 121 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 180

Query: 181 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 240
           FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
Sbjct: 181 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 240

Query: 241 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 300
           AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
Sbjct: 241 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 300

Query: 301 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 360
           YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
Sbjct: 301 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 360

Query: 361 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 420
           SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
Sbjct: 361 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 420

Query: 421 ST 422
           ST
Sbjct: 421 ST 422


>gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
          Length = 397

 Score =  795 bits (2054), Expect = 0.0
 Identities = 396/422 (93%), Positives = 397/422 (94%), Gaps = 25/422 (5%)

Query: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60
           MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
Sbjct: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60

Query: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 120
           SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ                        
Sbjct: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ------------------------ 96

Query: 121 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 180
           NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
Sbjct: 97  NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 156

Query: 181 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 240
           FLKEAEDFTIFIKNHIRFPKFNFS +NVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
Sbjct: 157 FLKEAEDFTIFIKNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 215

Query: 241 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 300
           AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
Sbjct: 216 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 275

Query: 301 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 360
           YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
Sbjct: 276 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 335

Query: 361 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 420
           SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
Sbjct: 336 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395

Query: 421 ST 422
           ST
Sbjct: 396 ST 397


>gi|28416927 purinergic receptor P2X4 [Homo sapiens]
          Length = 388

 Score =  370 bits (950), Expect = e-102
 Identities = 194/389 (49%), Positives = 258/389 (66%), Gaps = 32/389 (8%)

Query: 6   CKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSA 65
           C  L   LF+Y T + V+ +++KVGL+ R +Q  ILAY++ WVF+ +KGYQ+ D S+ S+
Sbjct: 5   CAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETD-SVVSS 63

Query: 66  VITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIP 125
           V TKVKGVA TNTS LG RIWDVADYVIPAQ EN  FV+TN+I+T NQ Q +C E   IP
Sbjct: 64  VTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPE---IP 120

Query: 126 DG--ACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-PEEPFL 182
           D    C  D+ C AG A T  NGV TGRC+      + TCE+ AWCP+E  +  P+  FL
Sbjct: 121 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-TCEVAAWCPVEDDTHVPQPAFL 179

Query: 183 KEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCPIFRLGSVIRWA 241
           K AE+FT+ +KN+I +PKFNFSK N++     ++LKSC +  K + +CPIFRLG ++  A
Sbjct: 180 KAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENA 239

Query: 242 GSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNK-LSKSVSSGYNFRFARY 300
           G  FQD+A+EGG++GI + W+C+LD+AAS C P YSF RLD + +  +VS GYNFRFA+Y
Sbjct: 240 GHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKY 299

Query: 301 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFF----------------------CDLVLIY 338
           YRD AG E RTL+KAYGIRFD++V GK   F                      CD++++Y
Sbjct: 300 YRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLY 359

Query: 339 LIKKREFYRDKKYEEVRGLEDSSQEAEDE 367
            +KKR +YR+KKY+ V   E       D+
Sbjct: 360 CMKKRLYYREKKYKYVEDYEQGLASELDQ 388


>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
          Length = 178

 Score =  365 bits (937), Expect = e-101
 Identities = 178/178 (100%), Positives = 178/178 (100%)

Query: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60
           MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
Sbjct: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60

Query: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 120
           SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
Sbjct: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 120

Query: 121 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPE 178
           NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPE
Sbjct: 121 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPE 178


>gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]
          Length = 441

 Score =  341 bits (875), Expect = 6e-94
 Identities = 172/366 (46%), Positives = 231/366 (63%), Gaps = 32/366 (8%)

Query: 13  LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITKVKG 72
           L DYKTEKYV+ +N +VG L RLLQ  I+ Y+V W  L KKGYQ+ D   Q ++ITK+KG
Sbjct: 22  LLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQERDLEPQFSIITKLKG 81

Query: 73  VAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPDGACSKD 132
           V+ T   +LG R+WDVAD+V P QGENVFF+VTN +VTP Q Q  C E+  +P   C  D
Sbjct: 82  VSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVD 141

Query: 133 SDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFI 192
            DC  GE  T  +GVKTG+C+      R TCEI++WCP+E+   P  P L +A++FT+FI
Sbjct: 142 EDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIWSWCPVESGVVPSRPLLAQAQNFTLFI 200

Query: 193 KNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCPIFRLGSVIRWAGSDFQDIALE 251
           KN + F KFNFSKSN ++  D ++ K C + P+ + YCP+FR+G ++  AG  F+D+AL 
Sbjct: 201 KNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALL 260

Query: 252 GGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRT 311
           GG +GI + W+CDLD   S C PHYSF +L  K        YNFR A ++ +  GVE RT
Sbjct: 261 GGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK-------SYNFRTATHWWEQPGVEART 312

Query: 312 LMKAYGIRFDVMVNGKG----------------------AFFCDLVLIYLIKKREFYRDK 349
           L+K YGIRFD++V G+                        FFCDL+L+Y+ ++  FY   
Sbjct: 313 LLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLLLYVDREAHFYWRT 372

Query: 350 KYEEVR 355
           KYEE +
Sbjct: 373 KYEEAK 378


>gi|4505545 purinergic receptor P2X1 [Homo sapiens]
          Length = 399

 Score =  310 bits (795), Expect = 1e-84
 Identities = 165/396 (41%), Positives = 243/396 (61%), Gaps = 35/396 (8%)

Query: 9   LCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVIT 68
           L   LF+Y T + V+ +NKKVG+++RL+Q  +L Y++ WVFL +KGYQ   + L S+V  
Sbjct: 9   LAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQ-TSSGLISSVSV 67

Query: 69  KVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAEN-EGIPDG 127
           K+KG+A T    LG ++WDVADYV PAQG+N F V+TN IVTP Q Q  CAE+ EG   G
Sbjct: 68  KLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEG---G 124

Query: 128 ACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-PEEPFLKEAE 186
            C +DS C  G+A     G++TG+C+   +  + TCEIF WCP+E     P    L+EAE
Sbjct: 125 ICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVK-TCEIFGWCPVEVDDDIPRPALLREAE 183

Query: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
           +FT+FIKN I FP+F  ++ N+++  + + +K+C F    H  CP+F+LG V++ +G +F
Sbjct: 184 NFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNF 243

Query: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
             +A +GGV+GI I+W+CDLD     C P Y F  L  +  K++S G+NFRFAR++ +  
Sbjct: 244 STLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEE--KNLSPGFNFRFARHFVE-N 300

Query: 306 GVEFRTLMKAYGIRFDVMVNGKGAFF----------------------CDLVLIYLIKKR 343
           G  +R L K +GIRFD++V+GK   F                      CDL+L++++ KR
Sbjct: 301 GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR 360

Query: 344 EFYRDK--KYEEVRGLEDSSQEAEDEASGLGLSEQL 377
            +Y+ K  KY E  G   + ++    +S LGL E +
Sbjct: 361 HYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENM 396


>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
          Length = 397

 Score =  308 bits (788), Expect = 8e-84
 Identities = 168/370 (45%), Positives = 227/370 (61%), Gaps = 36/370 (9%)

Query: 10  CLS-LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVIT 68
           C+S  F Y+T K V+ K+  +G++ R++Q  I++Y V WVFL +K YQ  DT+++S+V+T
Sbjct: 3   CISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVT 62

Query: 69  KVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPDGA 128
           KVKG           R+ DV+DYV P QG +VF ++T +IVT NQ Q  C E+E      
Sbjct: 63  KVKGSGL-----YANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESE--EKYR 115

Query: 129 CSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDF 188
           C  DS C  G     G G+ TGRC+   ++ R TCEI  WCP E  +  E P + EAE+F
Sbjct: 116 CVSDSQC--GPERLPGGGILTGRCVNYSSVLR-TCEIQGWCPTEVDT-VETPIMMEAENF 171

Query: 189 TIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGP-KNHYCPIFRLGSVIRWAGSDFQD 247
           TIFIKN IRFP FNF K N++       +K+C F P K+ +CPI R+G V+++AG DF  
Sbjct: 172 TIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAK 231

Query: 248 IALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK-SVSSGYNFRFARYYRDAAG 306
           +A  GGV+GI I W CDLDKA  +C P YSF+RLD+   K SVS GYNFRFA+YY+   G
Sbjct: 232 LARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENG 291

Query: 307 VEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKRE 344
            E+RTL+KA+GIRFDV+V G                       G   CD++L+  +K  +
Sbjct: 292 SEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGAD 351

Query: 345 FYRDKKYEEV 354
            Y+ KK+EEV
Sbjct: 352 QYKAKKFEEV 361


>gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
          Length = 471

 Score =  305 bits (781), Expect = 5e-83
 Identities = 169/437 (38%), Positives = 249/437 (56%), Gaps = 41/437 (9%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
           ITKVKG+    TS+   ++WDV +YV P +G +VF ++T +  T +Q Q  C E+  + +
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133

Query: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 186
             C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +     A 
Sbjct: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193

Query: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
           +FTI IKN I +PKF+FSK N+ D  D  +LK C F   +  YCPIF+LG ++  AG  F
Sbjct: 194 NFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 252

Query: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
            ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   
Sbjct: 253 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-IN 310

Query: 306 GVEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKR 343
           G   RTL+KAYGIR DV+V+G+                      G+F CD +L+  + K 
Sbjct: 311 GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKN 370

Query: 344 EFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSS 403
           + Y  KK+++V      +      +  + L+  L   P   G   + +   PP  + G  
Sbjct: 371 KVYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ- 424

Query: 404 SQKGNGSVCPQLLEPHR 420
                G+ C     P R
Sbjct: 425 ----QGAECGPAFPPLR 437


>gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]
          Length = 415

 Score =  303 bits (777), Expect = 1e-82
 Identities = 152/332 (45%), Positives = 206/332 (62%), Gaps = 32/332 (9%)

Query: 47  WVFLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTN 106
           W  L KKGYQ+ D   Q ++ITK+KGV+ T   +LG R+WDVAD+V P QGENVFF+VTN
Sbjct: 30  WALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTN 89

Query: 107 LIVTPNQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIF 166
            +VTP Q Q  C E+  +P   C  D DC  GE  T  +GVKTG+C+      R TCEI+
Sbjct: 90  FLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIW 148

Query: 167 AWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK- 225
           +WCP+E+   P  P L +A++FT+FIKN + F KFNFSKSN ++  D ++ K C + P+ 
Sbjct: 149 SWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQF 208

Query: 226 NHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKL 285
           + YCP+FR+G ++  AG  F+D+AL GG +GI + W+CDLD   S C PHYSF +L  K 
Sbjct: 209 SPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK- 266

Query: 286 SKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGKG----------------- 328
                  YNFR A ++ +  GVE RTL+K YGIRFD++V G+                  
Sbjct: 267 ------SYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAA 320

Query: 329 -----AFFCDLVLIYLIKKREFYRDKKYEEVR 355
                 FFCDL+L+Y+ ++  FY   KYEE +
Sbjct: 321 WLGVVTFFCDLLLLYVDREAHFYWRTKYEEAK 352


>gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]
          Length = 404

 Score =  303 bits (776), Expect = 2e-82
 Identities = 157/371 (42%), Positives = 230/371 (61%), Gaps = 31/371 (8%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
           ITKVKG+    TS+   ++WDV +YV P +G +VF ++T +  T +Q Q  C E+  + +
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133

Query: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 186
             C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +     A 
Sbjct: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193

Query: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
           +FTI IKN I +PKF+FSK N+ D  D  +LK C F   +  YCPIF+LG ++  AG  F
Sbjct: 194 NFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 252

Query: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
            ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   
Sbjct: 253 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-IN 310

Query: 306 GVEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKR 343
           G   RTL+KAYGIR DV+V+G+                      G+F CD +L+  + K 
Sbjct: 311 GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKN 370

Query: 344 EFYRDKKYEEV 354
           + Y  KK++++
Sbjct: 371 KVYSHKKFDKM 381


>gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
          Length = 497

 Score =  295 bits (755), Expect = 5e-80
 Identities = 169/463 (36%), Positives = 249/463 (53%), Gaps = 67/463 (14%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
           ITKVKG+    TS+   ++WDV +YV P +G +VF ++T +  T +Q Q  C E+  + +
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133

Query: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 186
             C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +     A 
Sbjct: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193

Query: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
           +FTI IKN I +PKF+FSK N+ D  D  +LK C F   +  YCPIF+LG ++  AG  F
Sbjct: 194 NFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 252

Query: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
            ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   
Sbjct: 253 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-IN 310

Query: 306 GVEFRTLMKAYGIRFDVMVNG--------------------------------------- 326
           G   RTL+KAYGIR DV+V+G                                       
Sbjct: 311 GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGGSTR 370

Query: 327 ---------KGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQL 377
                    +G+F CD +L+  + K + Y  KK+++V      +      +  + L+  L
Sbjct: 371 PLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKV-----CTPSHPSGSWPVTLARVL 425

Query: 378 TSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 420
              P   G   + +   PP  + G       G+ C     P R
Sbjct: 426 GQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 463


>gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
          Length = 447

 Score =  274 bits (701), Expect = 1e-73
 Identities = 161/437 (36%), Positives = 234/437 (53%), Gaps = 65/437 (14%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
           ITKVKG+    TS+   ++WDV +YV P +   V                         +
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPESIRVH------------------------N 109

Query: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 186
             C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +     A 
Sbjct: 110 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 169

Query: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
           +FTI IKN I +PKF+FSK N+ D  D  +LK C F   +  YCPIF+LG ++  AG  F
Sbjct: 170 NFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 228

Query: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
            ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   
Sbjct: 229 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-IN 286

Query: 306 GVEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKR 343
           G   RTL+KAYGIR DV+V+G+                      G+F CD +L+  + K 
Sbjct: 287 GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKN 346

Query: 344 EFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSS 403
           + Y  KK+++V      +      +  + L+  L   P   G   + +   PP  + G  
Sbjct: 347 KVYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ- 400

Query: 404 SQKGNGSVCPQLLEPHR 420
                G+ C     P R
Sbjct: 401 ----QGAECGPAFPPLR 413


>gi|29294631 purinergic receptor P2X7 [Homo sapiens]
          Length = 595

 Score =  219 bits (557), Expect = 5e-57
 Identities = 131/341 (38%), Positives = 186/341 (54%), Gaps = 20/341 (5%)

Query: 10  CLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITK 69
           C  +F Y+T K    ++   G +       I +Y V +  +  K YQ  +  + S+V TK
Sbjct: 7   CSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEPVI-SSVHTK 64

Query: 70  VKGVAFTN-------TSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENE 122
           VKG+A             L   ++D ADY  P QG N FFV+TN + T  Q Q +C E  
Sbjct: 65  VKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQRLCPEYP 123

Query: 123 GIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLET-SSRPEEPF 181
                 CS D  C  G       G++TGRC+  E   + TCE+ AWCP+E     P    
Sbjct: 124 -TRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQK-TCEVSAWCPIEAVEEAPRPAL 181

Query: 182 LKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGP-KNHYCPIFRLGSVIRW 240
           L  AE+FT+ IKN+I FP  N++  N++         +C F   +N  CPIFRLG + R 
Sbjct: 182 LNSAENFTVLIKNNIDFPGHNYTTRNILP----GLNITCTFHKTQNPQCPIFRLGDIFRE 237

Query: 241 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK-SVSSGYNFRFAR 299
            G +F D+A++GG++GI I W+C+LD+    C P YSF RLD+K +  S+  GYNFR+A+
Sbjct: 238 TGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAK 297

Query: 300 YYRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLI 340
           YY++   VE RTL+K +GIRFD++V G G  F  + L+  I
Sbjct: 298 YYKE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYI 337


>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
          Length = 379

 Score =  212 bits (539), Expect = 6e-55
 Identities = 123/320 (38%), Positives = 170/320 (53%), Gaps = 36/320 (11%)

Query: 124 IPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLK 183
           + +  C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +    
Sbjct: 39  VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGT 98

Query: 184 EAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAG 242
            A +FTI IKN I +PKF+FSK N+ D  D  +LK C F   +  YCPIF+LG ++  AG
Sbjct: 99  MAPNFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAG 157

Query: 243 SDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYR 302
             F ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+
Sbjct: 158 ESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK 216

Query: 303 DAAGVEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLI 340
              G   RTL+KAYGIR DV+V+G+                      G+F CD +L+  +
Sbjct: 217 -INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM 275

Query: 341 KKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKR 400
            K + Y  KK+++V      +      +  + L+  L   P   G   + +   PP  + 
Sbjct: 276 NKNKVYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQE 330

Query: 401 GSSSQKGNGSVCPQLLEPHR 420
           G       G+ C     P R
Sbjct: 331 GQ-----QGAECGPAFPPLR 345


>gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
          Length = 399

 Score =  194 bits (492), Expect = 2e-49
 Identities = 115/301 (38%), Positives = 159/301 (52%), Gaps = 36/301 (11%)

Query: 143 AGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFN 202
           A  G++TGRC+        TCE+F WCP+E  +   +     A +FTI IKN I +PKF+
Sbjct: 78  APRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFH 137

Query: 203 FSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEW 261
           FSK N+ D  D  +LK C F   +  YCPIF+LG ++  AG  F ++A +GGVIG+ I W
Sbjct: 138 FSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINW 196

Query: 262 NCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFD 321
           +CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   G   RTL+KAYGIR D
Sbjct: 197 DCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-INGTTTRTLIKAYGIRID 254

Query: 322 VMVNGK----------------------GAFFCDLVLIYLIKKREFYRDKKYEEVRGLED 359
           V+V+G+                      G+F CD +L+  + K + Y  KK+++V     
Sbjct: 255 VIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV----- 309

Query: 360 SSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPH 419
            +      +  + L+  L   P   G   + +   PP  + G       G+ C     P 
Sbjct: 310 CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPL 364

Query: 420 R 420
           R
Sbjct: 365 R 365


>gi|170763517 transforming, acidic coiled-coil containing protein 1
           isoform 1 [Homo sapiens]
          Length = 805

 Score = 34.3 bits (77), Expect = 0.22
 Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 7/116 (6%)

Query: 164 EIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNV-----MDVKDRSFLK 218
           E+   C  +T S+P E  + +    +  +KN    P+ +FSK ++     ++ KD + + 
Sbjct: 104 EVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDIS 163

Query: 219 SCHFGPKNHYCPIFRLGSVIRWAGSD-FQDIALEGGVIGINIEWNCDLD-KAASEC 272
           +       H C     G  +  +  D  QD A+  G +G+ +E + + D KA + C
Sbjct: 164 AVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSC 219


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 18/76 (23%), Positives = 37/76 (48%)

Query: 338 YLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPE 397
           + ++++  Y  +K +E+  +ED ++     A G G  E+   GPG  G+P + +  E   
Sbjct: 631 WALQRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSGIPVRSQGAEGLL 690

Query: 398 AKRGSSSQKGNGSVCP 413
           A+     + G+ +  P
Sbjct: 691 ARIHHGDRGGSRTALP 706


>gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]
          Length = 317

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 18/45 (40%), Positives = 23/45 (51%)

Query: 338 YLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPG 382
           YL K   FY   K   V+G  DSS+E  D++S     E+ TS  G
Sbjct: 44  YLYKHAYFYPHLKRFPVQGSSDSSEENGDDSSEEEEEEEETSNEG 88


>gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 13/38 (34%), Positives = 20/38 (52%)

Query: 372 GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNG 409
           GL E L +G   LG+PE+ +   P       ++Q G+G
Sbjct: 84  GLQEPLCTGGNSLGIPEESQASSPTLTASSPNAQDGSG 121


>gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 13/38 (34%), Positives = 20/38 (52%)

Query: 372 GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNG 409
           GL E L +G   LG+PE+ +   P       ++Q G+G
Sbjct: 84  GLQEPLCTGGNSLGIPEESQASSPTLTASSPNAQDGSG 121


>gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo
           sapiens]
          Length = 362

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 13/38 (34%), Positives = 20/38 (52%)

Query: 372 GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNG 409
           GL E L +G   LG+PE+ +   P       ++Q G+G
Sbjct: 84  GLQEPLCTGGNSLGIPEESQASSPTLTASSPNAQDGSG 121


>gi|116089333 kelch domain containing 7A [Homo sapiens]
          Length = 777

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 2/90 (2%)

Query: 321 DVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSG 380
           D+ + GK       +L+  +  R  Y+ +     R   +   EA++EA G G      + 
Sbjct: 14  DMQLTGKVVLSAAALLLVTVAYR-LYKSRPAPAQRWGGNGQAEAKEEAEGSGQPAVQEAS 72

Query: 381 PG-LLGMPEQQELQEPPEAKRGSSSQKGNG 409
           PG LL  P ++   +  EA +G S +   G
Sbjct: 73  PGVLLRGPRRRRSSKRAEAPQGCSCENPRG 102


>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
           exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 10/69 (14%)

Query: 356 GLEDSSQEAEDE-------ASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGN 408
           GLE SSQ    E           G S     G   LG+PEQ +LQE    ++   SQ  +
Sbjct: 293 GLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEK---SQSAS 349

Query: 409 GSVCPQLLE 417
               P++LE
Sbjct: 350 VESIPEVLE 358


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 358 EDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRG-SSSQKGNGSVCPQLL 416
           E+  +E EDE+S  G  E+ +S   L+G        E      G +SS  G+G     L 
Sbjct: 100 EEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLE 159

Query: 417 EP 418
           EP
Sbjct: 160 EP 161


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 358 EDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRG-SSSQKGNGSVCPQLL 416
           E+  +E EDE+S  G  E+ +S   L+G        E      G +SS  G+G     L 
Sbjct: 100 EEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLE 159

Query: 417 EP 418
           EP
Sbjct: 160 EP 161


>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
          Length = 1989

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 5/55 (9%)

Query: 357 LEDSSQEAEDEASGL-GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGS 410
           LED     +D  S +   S   +SG GLL  P ++    PP + RG  S  G GS
Sbjct: 22  LEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRR----PPHSARGGGSGGGGGS 72


>gi|33859793 hypothetical protein LOC139212 [Homo sapiens]
          Length = 214

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 16/58 (27%), Positives = 25/58 (43%)

Query: 357 LEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQ 414
           L    ++  D     GLS     GPG +G P+ +EL+  PE    ++    N    P+
Sbjct: 39  LNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPE 96


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,149,478
Number of Sequences: 37866
Number of extensions: 727947
Number of successful extensions: 2321
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2237
Number of HSP's gapped (non-prelim): 29
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.