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Search of human proteins with 28373101
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
(376 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 782 0.0
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 264 9e-71
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 256 3e-68
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 165 7e-41
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 160 1e-39
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 142 6e-34
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 72 1e-12
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 72 1e-12
gi|192448440 sialyltransferase 7B [Homo sapiens] 71 2e-12
gi|21264332 sialyltransferase 7A [Homo sapiens] 64 2e-10
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 63 4e-10
gi|28373099 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 61 1e-09
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 61 2e-09
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 57 2e-08
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 57 2e-08
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 55 1e-07
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 54 2e-07
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 54 2e-07
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 54 3e-07
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 54 3e-07
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 54 3e-07
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 54 3e-07
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 54 3e-07
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 54 3e-07
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 52 1e-06
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 49 6e-06
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 49 6e-06
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 49 1e-05
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 45 1e-04
gi|13569938 sialyltransferase 7E [Homo sapiens] 44 2e-04
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 782 bits (2019), Expect = 0.0
Identities = 376/376 (100%), Positives = 376/376 (100%)
Query: 1 MRYADPSANRDLLGSRTLLFIFICAFALVTLLQQILYGRNYIKRYFEFYEGPFEYNSTRC 60
MRYADPSANRDLLGSRTLLFIFICAFALVTLLQQILYGRNYIKRYFEFYEGPFEYNSTRC
Sbjct: 1 MRYADPSANRDLLGSRTLLFIFICAFALVTLLQQILYGRNYIKRYFEFYEGPFEYNSTRC 60
Query: 61 LELRHEILEVKVLSMVKQSELFDRWKSLQMCKWAMNISEANQFKSTLSRCCNAPAFLFTT 120
LELRHEILEVKVLSMVKQSELFDRWKSLQMCKWAMNISEANQFKSTLSRCCNAPAFLFTT
Sbjct: 61 LELRHEILEVKVLSMVKQSELFDRWKSLQMCKWAMNISEANQFKSTLSRCCNAPAFLFTT 120
Query: 121 QKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGR 180
QKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGR
Sbjct: 121 QKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGR 180
Query: 181 EINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYE 240
EINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYE
Sbjct: 181 EINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYE 240
Query: 241 NASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRIS 300
NASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRIS
Sbjct: 241 NASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRIS 300
Query: 301 TGLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHL 360
TGLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHL
Sbjct: 301 TGLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHL 360
Query: 361 HSRGILRVHTGTCSCC 376
HSRGILRVHTGTCSCC
Sbjct: 361 HSRGILRVHTGTCSCC 376
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 264 bits (675), Expect = 9e-71
Identities = 124/286 (43%), Positives = 178/286 (62%)
Query: 88 LQMCKWAMNISEANQFKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIF 147
+Q C W E F++ L+ CC+A +Q NTP+GT + YEV++ I + IF
Sbjct: 110 IQSCPWKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIF 169
Query: 148 RMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVK 207
MFP P+ + +CAVVGNGGIL S CG EI+ +DFVFRCNLPP + + DVG K
Sbjct: 170 HMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSK 229
Query: 208 TDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDD 267
T++VT+NPSIIT ++ L++ + F + Y +A LLPAF NT S +V Y L++
Sbjct: 230 TNLVTINPSIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEE 289
Query: 268 FESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMN 327
++ Q V +FHP+YL +++ +W + GV A R+STGL++ + A+ELC+ V L+GFW F
Sbjct: 290 SKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKT 349
Query: 328 PSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTC 373
+ ++HHYYDN P+ GFH MP E L LH +GIL++ C
Sbjct: 350 VEDIPVSHHYYDNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKC 395
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 256 bits (653), Expect = 3e-68
Identities = 127/282 (45%), Positives = 179/282 (63%), Gaps = 3/282 (1%)
Query: 93 WAMNISEANQFKSTLSRCCNAPAFLFT-TQKNTPLGTKLKYEVDTSGIYHINQEIFRMFP 151
W N + A F+ + CC+ PA LF T+ N+P+G + Y+ + + I+ + +FP
Sbjct: 68 WRRNQTAARAFRKQMEDCCD-PAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNSTYSLFP 126
Query: 152 KDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVV 211
+ P+ + KKCAVVGNGGILK S CGR+I+ A+FV RCNLPP+S +YT DVG K+ +V
Sbjct: 127 QATPF-QLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLV 185
Query: 212 TVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
T NPSII +RF L R+ F +++Y ++ + +PAF T+ S+RV Y L D +
Sbjct: 186 TANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGAN 245
Query: 272 QAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGL 331
Q V + +P +L ++ ++W S G+ AKR+STGL LV+AAL LCEEV ++GFW F +N
Sbjct: 246 QTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQ 305
Query: 332 YITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTC 373
I+HHYYDNV P GFHAMP E +LH G LR+ C
Sbjct: 306 PISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPC 347
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 165 bits (417), Expect = 7e-41
Identities = 96/287 (33%), Positives = 150/287 (52%), Gaps = 7/287 (2%)
Query: 93 WAMNISEANQFKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIFRMFPK 152
W +N S + + + R +A + + + G + Y +D +I+ ++ + P+
Sbjct: 71 WKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPE 130
Query: 153 DMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVT 212
P +FK CAVVGN GIL +S CG+EI+S +FV RCNL P+ E + DVG K+D +T
Sbjct: 131 VSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVE-FAADVGTKSDFIT 189
Query: 213 VNPSIITERF--HKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFES 270
+NPS++ F + E R F L + ++ + +PAF V ++ +
Sbjct: 190 MNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKL 249
Query: 271 PQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSG 330
Y + + V YWL+ V KR STGL++ T A C+E+HL+GFW FP + +G
Sbjct: 250 KVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNG 309
Query: 331 LYITHHYYDNVKPR----PGFHAMPSEIFNFLHLHSRGILRVHTGTC 373
+ +HYYD++K R H MP E LH+RG L++ TG C
Sbjct: 310 KAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKC 356
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 160 bits (406), Expect = 1e-39
Identities = 90/288 (31%), Positives = 145/288 (50%), Gaps = 7/288 (2%)
Query: 92 KWAMNISEANQFKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIFRMFP 151
KW N + + + + + + +A + + G + Y D +++Q ++ + P
Sbjct: 85 KWRHNQTLSLRIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDSTMNVSQNLYELLP 144
Query: 152 KDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVV 211
+ P F CA+VGN G+L NS CG+EI++ FV RCNL P+ E Y DVG+KTD+V
Sbjct: 145 RTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQE-YARDVGLKTDLV 203
Query: 212 TVNPSIITERFHKL--EKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFE 269
T+NPS+I F L WR + L + + +PAF + V ++
Sbjct: 204 TMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKHH 263
Query: 270 SPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPS 329
Y + L V YWL+ V KR +TGL++ T A C++++L+GFW FP++ +
Sbjct: 264 VNVRTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQN 323
Query: 330 GLYITHHYYDNVK----PRPGFHAMPSEIFNFLHLHSRGILRVHTGTC 373
+ +HYYD++K + H MP E LH +G L++ G C
Sbjct: 324 QNPVKYHYYDSLKYGYTSQASPHTMPLEFKALKSLHEQGALKLTVGQC 371
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 142 bits (357), Expect = 6e-34
Identities = 81/265 (30%), Positives = 141/265 (53%), Gaps = 11/265 (4%)
Query: 120 TQKNTPLGTKLKYEVDTSG-IYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRC 178
T+ + +G + Y+ + ++ I+ + P P + CAVVGN GIL S+C
Sbjct: 117 TKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQC 176
Query: 179 GREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKL--EKWRRPFYRVL 236
G+EI+ +DFVFRCN P +E + DVG KT++ T NPSI+ + ++ L + R F+ L
Sbjct: 177 GQEIDKSDFVFRCNFAP-TEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSL 235
Query: 237 QVYENASVLLPA-FYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVR 295
+ + A + +PA F++T T V + ++ + + + +V+RYW + +
Sbjct: 236 KKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295
Query: 296 AKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLY-ITHHYYDNVKPR-----PGFHA 349
KR+STG+++ T A +CEE+HL+GFW F +P+ + +HYYD + H
Sbjct: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQ 355
Query: 350 MPSEIFNFLHLHSRGILRVHTGTCS 374
+P+E +H G+ ++ C+
Sbjct: 356 LPAEFQLLYRMHGEGLTKLTLSHCA 380
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 71.6 bits (174), Expect = 1e-12
Identities = 62/217 (28%), Positives = 101/217 (46%), Gaps = 21/217 (9%)
Query: 129 KLKYEVDTSGIYHINQEIFRMFPKDM-PYYRSQF---KKCAVVGNGGILKNSRCGREINS 184
+L+ E + + +E+FR+ P ++ P + ++CAVVGN G L+ S G EI+S
Sbjct: 103 RLQREKKPNNLNDTIKELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDS 162
Query: 185 ADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASV 244
DFV R N P + + DVG KT V P E + PF + + +++
Sbjct: 163 HDFVLRMNKAP-TAGFEADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAI 221
Query: 245 LLPAFYNTR-NTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGL 303
+T IRVK + +HP ++ V WL + STG+
Sbjct: 222 TTGTISHTYIPVPAKIRVK--------QDKILIYHPAFIKYVFDNWLQ--GHGRYPSTGI 271
Query: 304 ILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDN 340
+ V ++ +C+EV L+GF A + G + HHY++N
Sbjct: 272 LSVIFSMHVCDEVDLYGFGA---DSKGNW--HHYWEN 303
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 71.6 bits (174), Expect = 1e-12
Identities = 62/217 (28%), Positives = 101/217 (46%), Gaps = 21/217 (9%)
Query: 129 KLKYEVDTSGIYHINQEIFRMFPKDM-PYYRSQF---KKCAVVGNGGILKNSRCGREINS 184
+L+ E + + +E+FR+ P ++ P + ++CAVVGN G L+ S G EI+S
Sbjct: 103 RLQREKKPNNLNDTIKELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDS 162
Query: 185 ADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASV 244
DFV R N P + + DVG KT V P E + PF + + +++
Sbjct: 163 HDFVLRMNKAP-TAGFEADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAI 221
Query: 245 LLPAFYNTR-NTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGL 303
+T IRVK + +HP ++ V WL + STG+
Sbjct: 222 TTGTISHTYIPVPAKIRVK--------QDKILIYHPAFIKYVFDNWLQ--GHGRYPSTGI 271
Query: 304 ILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDN 340
+ V ++ +C+EV L+GF A + G + HHY++N
Sbjct: 272 LSVIFSMHVCDEVDLYGFGA---DSKGNW--HHYWEN 303
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 70.9 bits (172), Expect = 2e-12
Identities = 77/287 (26%), Positives = 128/287 (44%), Gaps = 57/287 (19%)
Query: 120 TQKNTPLGTK-LKYEVDTSGIYHIN-QEIFRMF--PKDMPYYRSQFKKCAVVGNGGILKN 175
+Q P G + L ++V S + +N E ++F P+D P + +CAVVGNGGIL
Sbjct: 106 SQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTP---PKCIRCAVVGNGGILNG 162
Query: 176 SRCGREINSADFVFRCNLPPISEKYTMDVGVKTDV--VTVNPSIITERFHKLEKWRRPFY 233
SR G I++ D+VFR N + + + DVG KT TVN T + + W F
Sbjct: 163 SRQGPNIDAHDYVFRLN-GAVIKGFERDVGTKTSFYGFTVN----TMKNSLVSYWNLGFT 217
Query: 234 RVLQVYENASVLLPA----FYNTRNTDVSIRVKYVLDDFESPQAVY----------YFHP 279
V Q + + +P+ + R+ + + V LD + P A + HP
Sbjct: 218 SVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
Query: 280 QYLVNVSRYWLSLGVRAKRI----------STGLILVTAALELCEEVHLFGF-----WAF 324
++ ++ +L ++K I STG +++ AL C++V +GF W F
Sbjct: 278 DFISYLTERFL----KSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKF 333
Query: 325 PMNPSGLYITHHYYDNVKPRPGF--HAMPSEIFNFLHLHSRGILRVH 369
H++ +KP + H + E + LH GIL+++
Sbjct: 334 S--------DHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLY 372
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 64.3 bits (155), Expect = 2e-10
Identities = 64/239 (26%), Positives = 97/239 (40%), Gaps = 48/239 (20%)
Query: 164 CAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER-- 221
CAVVGNGGIL NS G+EI+S D+VFR + + + Y DVG +T +T+
Sbjct: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLS-GALIKGYEQDVGTRTSFYGFTAFSLTQSLL 423
Query: 222 ------------------FHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKY 263
H LE R + + + F+ + R
Sbjct: 424 ILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREAL 483
Query: 264 VLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAK----------RISTGLILVTAALELC 313
+D + HP +L RY + +R+K R +TG +L+ AL+LC
Sbjct: 484 HMDRY------LLLHPDFL----RYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLC 533
Query: 314 EEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGF---HAMPSEIFNFLHLHSRGILRVH 369
++V +GF + + HYYD R F H E + LH GI+R++
Sbjct: 534 DQVSAYGF----ITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLY 588
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 63.2 bits (152), Expect = 4e-10
Identities = 56/202 (27%), Positives = 97/202 (48%), Gaps = 22/202 (10%)
Query: 144 QEIFRMFPKDMPY-YRS--QFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKY 200
+++F++ P + PY +R Q ++CAVVGN G L+ S G++++ +F+ R N P + +
Sbjct: 129 EKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAP-TVGF 187
Query: 201 TMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVS-- 258
DVG +T + P + PF +VL + AS L V
Sbjct: 188 EQDVGSRTTHHFMYPESAKNLPANVSFVLVPF-KVLDLLWIASALSTGQIRFTYAPVKSF 246
Query: 259 IRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHL 318
+RV +P Y H ++ + RY STG++++ AL +C+EV++
Sbjct: 247 LRVDKEKVQIYNPAFFKYIHDRWTEHHGRY----------PSTGMLVLFFALHVCDEVNV 296
Query: 319 FGFWAFPMNPSGLYITHHYYDN 340
+GF A + G + HHY++N
Sbjct: 297 YGFGA---DSRGNW--HHYWEN 313
>gi|28373099 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform b [Homo sapiens]
Length = 168
Score = 61.2 bits (147), Expect = 1e-09
Identities = 31/98 (31%), Positives = 52/98 (53%)
Query: 93 WAMNISEANQFKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIFRMFPK 152
W +N S + + + R +A + + + G + Y +D +I+ ++ + P+
Sbjct: 71 WKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPE 130
Query: 153 DMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFR 190
P +FK CAVVGN GIL +S CG+EI+S +FV R
Sbjct: 131 VSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIR 168
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 60.8 bits (146), Expect = 2e-09
Identities = 56/201 (27%), Positives = 87/201 (43%), Gaps = 43/201 (21%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNP-SIITE 220
KKC VVGNGG+LKN G +I+S D + R N P+ + +VG +T P S+ ++
Sbjct: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVL-GHEEEVGRRTTFRLFYPESVFSD 174
Query: 221 RFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDD-------FESPQA 273
H N +V+L AF + D+ ++ ++ D ++ P
Sbjct: 175 PIHN--------------DPNTTVILTAF---KPHDLRWLLELLMGDKINTNGFWKKPAL 217
Query: 274 VYYFHP-------QYLVNVSRYWL-------SLGVRAKRISTGLILVTAALELCEEVHLF 319
+ P +++ + Y L + K +TG+I +T A +C EVHL
Sbjct: 218 NLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLA 277
Query: 320 GFWAFPMNPSGLYITHHYYDN 340
G F N S L HYY N
Sbjct: 278 G---FKYNFSDLKSPLHYYGN 295
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 9/195 (4%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
+ CAVV + G + NS G EI+S D V R N P + Y DVG KT + +N I+T
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAP-TRGYEKDVGNKTTIRIINSQILTNP 352
Query: 222 FHKLEKWRRPFYRVLQVYENA--SVLLPAFYNTRNTDVSIRVKYVLDDFESP-QAVYYFH 278
H +L ++ A S L +Y + D ++ Y+ +P Q Y H
Sbjct: 353 SHHFIDSSLYKDVILVAWDPAPYSANLNLWY--KKPDYNLFTPYIQHRQRNPNQPFYILH 410
Query: 279 PQY---LVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLYITH 335
P++ L ++ + ++ S+G I + + +C EVH++ + +
Sbjct: 411 PKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHE 470
Query: 336 HYYDNVKPRPGFHAM 350
YYD +H +
Sbjct: 471 LYYDAACTLGAYHPL 485
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 9/195 (4%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
+ CAVV + G + NS G EI+S D V R N P + Y DVG KT + +N I+T
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAP-TRGYEKDVGNKTTIRIINSQILTNP 352
Query: 222 FHKLEKWRRPFYRVLQVYENA--SVLLPAFYNTRNTDVSIRVKYVLDDFESP-QAVYYFH 278
H +L ++ A S L +Y + D ++ Y+ +P Q Y H
Sbjct: 353 SHHFIDSSLYKDVILVAWDPAPYSANLNLWY--KKPDYNLFTPYIQHRQRNPNQPFYILH 410
Query: 279 PQY---LVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLYITH 335
P++ L ++ + ++ S+G I + + +C EVH++ + +
Sbjct: 411 PKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHE 470
Query: 336 HYYDNVKPRPGFHAM 350
YYD +H +
Sbjct: 471 LYYDAACTLGAYHPL 485
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/208 (25%), Positives = 96/208 (46%), Gaps = 34/208 (16%)
Query: 151 PKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDV 210
PK++ R ++C VVGNG L+NS G IN D V R N P++ Y DVG KT +
Sbjct: 105 PKNIQSLRC--RRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVA-GYEGDVGSKTTM 161
Query: 211 VTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAF----YNTRNTDVSIRVKYVLD 266
P E H F ++ + ++L AF ++ T +S + +
Sbjct: 162 RLFYP----ESAH--------FDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKG 209
Query: 267 DFESPQAVYYFHPQYLVNVSRYWLSLGVR-------------AKRISTGLILVTAALELC 313
++ P ++ +P+ + ++ +++ + ++ +TGL+ +T AL LC
Sbjct: 210 FWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLC 269
Query: 314 EEVHLFGFWAFPMNPSGLYITHHYYDNV 341
+ VH+ GF +P + T HYY+ +
Sbjct: 270 DLVHIAGF-GYP-DAYNKKQTIHYYEQI 295
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/207 (25%), Positives = 90/207 (43%), Gaps = 14/207 (6%)
Query: 163 KCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIIT--E 220
+CAVV + G LK+S+ GREI+ D V R N P + + DVG KT + +N ++T +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP-TANFQQDVGTKTTIRLMNSQLVTTEK 241
Query: 221 RFHKLEKWRRPFYRVL--QVYENASVLLPAFYNTRNTDVSIRVKY-VLDDFESPQAVYYF 277
RF K + V VY + +P +Y +N D + Y Q Y
Sbjct: 242 RFLKDSLYNEGILIVWDPSVYHSD---IPKWY--QNPDYNFFNNYKTYRKLHPNQPFYIL 296
Query: 278 HPQY---LVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLYIT 334
PQ L ++ + ++ S+G++ + + LC++V ++ F Y
Sbjct: 297 KPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYY 356
Query: 335 HHYYDNVKPRPGFHAMPSEIFNFLHLH 361
++D+ +H + E HL+
Sbjct: 357 QKFFDSACTMGAYHPLLYEKNLVKHLN 383
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/207 (25%), Positives = 90/207 (43%), Gaps = 14/207 (6%)
Query: 163 KCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIIT--E 220
+CAVV + G LK+S+ GREI+ D V R N P + + DVG KT + +N ++T +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP-TANFQQDVGTKTTIRLMNSQLVTTEK 241
Query: 221 RFHKLEKWRRPFYRVL--QVYENASVLLPAFYNTRNTDVSIRVKY-VLDDFESPQAVYYF 277
RF K + V VY + +P +Y +N D + Y Q Y
Sbjct: 242 RFLKDSLYNEGILIVWDPSVYHSD---IPKWY--QNPDYNFFNNYKTYRKLHPNQPFYIL 296
Query: 278 HPQY---LVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLYIT 334
PQ L ++ + ++ S+G++ + + LC++V ++ F Y
Sbjct: 297 KPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYY 356
Query: 335 HHYYDNVKPRPGFHAMPSEIFNFLHLH 361
++D+ +H + E HL+
Sbjct: 357 QKFFDSACTMGAYHPLLYEKNLVKHLN 383
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 30/197 (15%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
++C +VGNGG+L N G I+ D V R N P+ + + DVG KT + P +R
Sbjct: 196 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV-KGFEKDVGSKTTLRITYPEGAMQR 254
Query: 222 FHKLE----------KWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
+ E KW+ + VY+ F+ + T V + P
Sbjct: 255 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP----------KEP 304
Query: 272 QAVYYFHPQYLVNVSRYWLSLGV------RAKRISTGLILVTAALELCEEVHLFGFWAFP 325
+ +P ++ + + L R + G + VT AL C+EV + GF
Sbjct: 305 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 364
Query: 326 MNPSGLYITHHYYDNVK 342
P+ HYY+ V+
Sbjct: 365 STPNA---PLHYYETVR 378
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 30/197 (15%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
++C +VGNGG+L N G I+ D V R N P+ + + DVG KT + P +R
Sbjct: 142 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV-KGFEKDVGSKTTLRITYPEGAMQR 200
Query: 222 FHKLE----------KWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
+ E KW+ + VY+ F+ + T V + P
Sbjct: 201 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP----------KEP 250
Query: 272 QAVYYFHPQYLVNVSRYWLSLGV------RAKRISTGLILVTAALELCEEVHLFGFWAFP 325
+ +P ++ + + L R + G + VT AL C+EV + GF
Sbjct: 251 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 310
Query: 326 MNPSGLYITHHYYDNVK 342
P+ HYY+ V+
Sbjct: 311 STPNA---PLHYYETVR 324
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 30/197 (15%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
++C +VGNGG+L N G I+ D V R N P+ + + DVG KT + P +R
Sbjct: 212 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV-KGFEKDVGSKTTLRITYPEGAMQR 270
Query: 222 FHKLE----------KWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
+ E KW+ + VY+ F+ + T V + P
Sbjct: 271 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP----------KEP 320
Query: 272 QAVYYFHPQYLVNVSRYWLSLGV------RAKRISTGLILVTAALELCEEVHLFGFWAFP 325
+ +P ++ + + L R + G + VT AL C+EV + GF
Sbjct: 321 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 380
Query: 326 MNPSGLYITHHYYDNVK 342
P+ HYY+ V+
Sbjct: 381 STPNA---PLHYYETVR 394
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 30/197 (15%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
++C +VGNGG+L N G I+ D V R N P+ + + DVG KT + P +R
Sbjct: 173 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV-KGFEKDVGSKTTLRITYPEGAMQR 231
Query: 222 FHKLE----------KWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
+ E KW+ + VY+ F+ + T V + P
Sbjct: 232 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP----------KEP 281
Query: 272 QAVYYFHPQYLVNVSRYWLSLGV------RAKRISTGLILVTAALELCEEVHLFGFWAFP 325
+ +P ++ + + L R + G + VT AL C+EV + GF
Sbjct: 282 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 341
Query: 326 MNPSGLYITHHYYDNVK 342
P+ HYY+ V+
Sbjct: 342 STPNA---PLHYYETVR 355
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 30/197 (15%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
++C +VGNGG+L N G I+ D V R N P+ + + DVG KT + P +R
Sbjct: 227 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV-KGFEKDVGSKTTLRITYPEGAMQR 285
Query: 222 FHKLE----------KWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
+ E KW+ + VY+ F+ + T V + P
Sbjct: 286 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP----------KEP 335
Query: 272 QAVYYFHPQYLVNVSRYWLSLGV------RAKRISTGLILVTAALELCEEVHLFGFWAFP 325
+ +P ++ + + L R + G + VT AL C+EV + GF
Sbjct: 336 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 395
Query: 326 MNPSGLYITHHYYDNVK 342
P+ HYY+ V+
Sbjct: 396 STPNA---PLHYYETVR 409
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 30/197 (15%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
++C +VGNGG+L N G I+ D V R N P+ + + DVG KT + P +R
Sbjct: 158 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV-KGFEKDVGSKTTLRITYPEGAMQR 216
Query: 222 FHKLE----------KWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
+ E KW+ + VY+ F+ + T V + P
Sbjct: 217 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP----------KEP 266
Query: 272 QAVYYFHPQYLVNVSRYWLSLGV------RAKRISTGLILVTAALELCEEVHLFGFWAFP 325
+ +P ++ + + L R + G + VT AL C+EV + GF
Sbjct: 267 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 326
Query: 326 MNPSGLYITHHYYDNVK 342
P+ HYY+ V+
Sbjct: 327 STPNA---PLHYYETVR 340
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 51.6 bits (122), Expect = 1e-06
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 20/200 (10%)
Query: 151 PKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDV 210
P P R + CAVV + G + S G EI+SA+ VFR N P + + DVG ++ +
Sbjct: 63 PDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAP-TVGFEADVGQRSTL 121
Query: 211 VTVN----PSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLD 266
V+ P ++ H +K R Y V + +L T T + + Y
Sbjct: 122 RVVSHTSVPLLLRNYSHYFQKARDTLYMVWGQGRHMDRVLGG--RTYRTLLQLTRMY--- 176
Query: 267 DFESPQAVYYFHPQYLVNVSRYWLSLGVRAKR-----ISTGLILVTAALELCEEVHLFGF 321
VY F + + + + + +R +STG + ALELCEE+ ++G
Sbjct: 177 ---PGLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGM 233
Query: 322 W--AFPMNPSGLYITHHYYD 339
++ S + +HY++
Sbjct: 234 VSDSYCREKSHPSVPYHYFE 253
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 49.3 bits (116), Expect = 6e-06
Identities = 56/227 (24%), Positives = 90/227 (39%), Gaps = 51/227 (22%)
Query: 144 QEIFRMFPK-DMPYY--RSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKY 200
Q + + P+ D+P + ++C V+G+GGIL G +N D V R N P+ E Y
Sbjct: 149 QTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPV-EGY 207
Query: 201 TMDVGVKTDVVTVNPS--------------IITERFHKLE---------KWRRPFYRVLQ 237
+ VG KT + P + F ++ K PF+ L
Sbjct: 208 SEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLF 267
Query: 238 VYENAS---VLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGV 294
++ + L P + N + + + + PQ SR+W
Sbjct: 268 FWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQ-------------SRFW----G 310
Query: 295 RAKRIST-GLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDN 340
R K + T G+I V A LC+EV L GF + +N + HY+D+
Sbjct: 311 RDKNVPTIGVIAVVLATHLCDEVSLAGF-GYDLNQPRTPL--HYFDS 354
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 49.3 bits (116), Expect = 6e-06
Identities = 56/227 (24%), Positives = 90/227 (39%), Gaps = 51/227 (22%)
Query: 144 QEIFRMFPK-DMPYY--RSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKY 200
Q + + P+ D+P + ++C V+G+GGIL G +N D V R N P+ E Y
Sbjct: 172 QTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPV-EGY 230
Query: 201 TMDVGVKTDVVTVNPS--------------IITERFHKLE---------KWRRPFYRVLQ 237
+ VG KT + P + F ++ K PF+ L
Sbjct: 231 SEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLF 290
Query: 238 VYENAS---VLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGV 294
++ + L P + N + + + + PQ SR+W
Sbjct: 291 FWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQ-------------SRFW----G 333
Query: 295 RAKRIST-GLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDN 340
R K + T G+I V A LC+EV L GF + +N + HY+D+
Sbjct: 334 RDKNVPTIGVIAVVLATHLCDEVSLAGF-GYDLNQPRTPL--HYFDS 377
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 48.5 bits (114), Expect = 1e-05
Identities = 38/124 (30%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
+ CAVV + G + NS G EI+S D V R N P + Y DVG KT + +N I+T
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAP-TRGYEKDVGNKTTIRIINSQILTNP 352
Query: 222 FHKLEKWRRPFYRVLQVYENA--SVLLPAFYNTRNTDVSIRVKYVLDDFESP-QAVYYFH 278
H +L ++ A S L +Y + D ++ Y+ +P Q Y H
Sbjct: 353 SHHFIDSSLYKDVILVAWDPAPYSANLNLWY--KKPDYNLFTPYIQHRQRNPNQPFYILH 410
Query: 279 PQYL 282
P+++
Sbjct: 411 PKFI 414
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 44.7 bits (104), Expect = 1e-04
Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER 221
++C +VGNGG+L N G I+ D V R N P+ + + DVG KT + P +R
Sbjct: 158 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV-KGFEKDVGSKTTLRITYPEGAMQR 216
Query: 222 FHKLEK 227
+ E+
Sbjct: 217 PEQYER 222
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 44.3 bits (103), Expect = 2e-04
Identities = 53/206 (25%), Positives = 84/206 (40%), Gaps = 46/206 (22%)
Query: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPS----I 217
+ CA+V + G L +SR G +I+ + V R N P + Y DVG +T + + S I
Sbjct: 94 RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAP-TRGYGRDVGNRTSLRVIAHSSIQRI 152
Query: 218 ITERFHKLEK--------WRRPFYRVL----QVYENASVL------LPAFYNTRNTDVSI 259
+ R L W Y QVY N +L L AF TR+ +
Sbjct: 153 LRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQF 212
Query: 260 RVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLF 319
+ + + + +S WLS TG +T ALELC+ ++++
Sbjct: 213 DELFKQETGKDRK------------ISNTWLS---------TGWFTMTIALELCDRINVY 251
Query: 320 GFWA--FPMNPSGLYITHHYYDNVKP 343
G F +P+ + +HYY+ P
Sbjct: 252 GMVPPDFCRDPNHPSVPYHYYEPFGP 277
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,110,758
Number of Sequences: 37866
Number of extensions: 589071
Number of successful extensions: 1428
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1371
Number of HSP's gapped (non-prelim): 45
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.