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Search of human proteins with 28373094
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
(218 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens] 454 e-128
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 454 e-128
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 257 6e-69
gi|13569938 sialyltransferase 7E [Homo sapiens] 215 3e-56
gi|21361444 sialytransferase 7F [Homo sapiens] 194 6e-50
gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens] 128 4e-30
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 67 2e-11
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 60 1e-09
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 60 1e-09
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 59 3e-09
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 59 3e-09
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 56 2e-08
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 55 5e-08
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 47 1e-05
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 47 1e-05
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 47 1e-05
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 47 1e-05
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 47 1e-05
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 47 1e-05
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 47 1e-05
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 44 8e-05
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 44 8e-05
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 43 2e-04
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 42 3e-04
gi|21264332 sialyltransferase 7A [Homo sapiens] 42 5e-04
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 40 0.002
gi|192448440 sialyltransferase 7B [Homo sapiens] 39 0.003
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 39 0.003
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 37 0.013
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 37 0.013
>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
Length = 218
Score = 454 bits (1167), Expect = e-128
Identities = 218/218 (100%), Positives = 218/218 (100%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR
Sbjct: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
Query: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR
Sbjct: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
Query: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 180
RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL
Sbjct: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 180
Query: 181 AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTE 218
AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTE
Sbjct: 181 AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTE 218
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 454 bits (1167), Expect = e-128
Identities = 218/218 (100%), Positives = 218/218 (100%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR
Sbjct: 85 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 144
Query: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR
Sbjct: 145 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 204
Query: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 180
RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL
Sbjct: 205 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 264
Query: 181 AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTE 218
AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTE
Sbjct: 265 AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTE 302
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 257 bits (656), Expect = 6e-69
Identities = 114/215 (53%), Positives = 157/215 (73%), Gaps = 1/215 (0%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
M+G +G EID + C++RMN APT G+E DVG+ + +RVVSHTSVPLLL+N ++F++A
Sbjct: 89 MVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKNPDYFFKEAN 148
Query: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
T+Y++WG R+M + G Y L + +YP Q+Y TE+ M+YCD +F+ ETGK+R
Sbjct: 149 TTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEKRMSYCDGVFKKETGKDR 208
Query: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 180
QSGS+LSTGWFT +LA++ C I VYGM++D+YC+ + + VPYHY+E+GR DEC Y
Sbjct: 209 VQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGYRKVPYHYYEQGR-DECDEYF 267
Query: 181 AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSW 215
HE AP HRFITEK VF++WAKK I+F HP+W
Sbjct: 268 LHEHAPYGGHRFITEKKVFAKWAKKHRIIFTHPNW 302
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 215 bits (547), Expect = 3e-56
Identities = 103/219 (47%), Positives = 144/219 (65%), Gaps = 1/219 (0%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+L S G++ID ECV RMN APT G+ DVG R++LRV++H+S+ +LRN ++
Sbjct: 105 LLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQ 164
Query: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
T+++ WG +M R G+ Y L L+++ P L+ + T M D++F+ ETGK+R
Sbjct: 165 GTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDR 224
Query: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 180
+ S ++LSTGWFTM +ALELC+ I VYGMV +CR+ +HPSVPYHY+E DEC MYL
Sbjct: 225 KISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYL 284
Query: 181 AHEQAPR-SAHRFITEKAVFSRWAKKRPIVFAHPSWRTE 218
+HE+ + S HRFITEK VF WA+ I F P W+ E
Sbjct: 285 SHERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPE 323
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 194 bits (492), Expect = 6e-50
Identities = 94/217 (43%), Positives = 139/217 (64%), Gaps = 3/217 (1%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+LG+ LG EI+ AEC RMN APT G+ ADVG ++T RVV+H+SV +LR + +
Sbjct: 117 LLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTP 176
Query: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
+T+++ WG M + G R + + ++P ++ Y + M D +F+ ETGK+R
Sbjct: 177 ETVFIFWGPPSKMQKPQGSLV-RVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDR 235
Query: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSH-PSVPYHYFEKGRLDECQMY 179
+S S+LSTGWFTM++A+ELC+ + VYGMV +YC ++ +PYHY+E DEC Y
Sbjct: 236 EKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKGPDECVTY 295
Query: 180 LAHEQAPR-SAHRFITEKAVFSRWAKKRPIVFAHPSW 215
+ +E + + + HRFITEK VFS WA+ I F+HPSW
Sbjct: 296 IQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSW 332
>gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]
Length = 210
Score = 128 bits (321), Expect = 4e-30
Identities = 57/119 (47%), Positives = 84/119 (70%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
M+G +G EID + C++RMN APT G+E DVG+ + +RVVSHTSVPLLL+N ++F++A
Sbjct: 89 MVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKNPDYFFKEAN 148
Query: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKN 119
T+Y++WG R+M + G Y L + +YP Q+Y TE+ M+YCD +F+ ETGK+
Sbjct: 149 TTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEKRMSYCDGVFKKETGKD 207
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 66.6 bits (161), Expect = 2e-11
Identities = 54/172 (31%), Positives = 74/172 (43%), Gaps = 21/172 (12%)
Query: 3 GSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQ--KAR 60
GSG G ++D + RMNQAPTVGFE DVG R+T + S L N S K
Sbjct: 163 GSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVL 222
Query: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
D L++ R TY + R+ E++ Y F+ +
Sbjct: 223 DLLWIASALSTGQIRF----TYAPVKSFLRV--------DKEKVQIYNPAFFKYIHDRWT 270
Query: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGR 172
G + STG + AL +C+E+ VYG +DS R H HY+E R
Sbjct: 271 EHHGRYPSTGMLVLFFALHVCDEVNVYGFGADS--RGNWH-----HYWENNR 315
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 60.1 bits (144), Expect = 1e-09
Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKA- 59
+L S LG EIDS + V R N APT G+E DVG ++T+R+++ +L N SH+F +
Sbjct: 305 ILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTNPSHHFIDSS 360
Query: 60 --RDTLYMVWGQGRHMDRV------LGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQI 111
+D + + W + + + +Q + P Y + + I
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
Query: 112 FQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSH 160
Q+ T + + + S+G+ +++ + +C E+ VY + E H
Sbjct: 421 IQENTKEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIPSVRQTELCH 467
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 60.1 bits (144), Expect = 1e-09
Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKA- 59
+L S LG EIDS + V R N APT G+E DVG ++T+R+++ +L N SH+F +
Sbjct: 305 ILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTNPSHHFIDSS 360
Query: 60 --RDTLYMVWGQGRHMDRV------LGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQI 111
+D + + W + + + +Q + P Y + + I
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
Query: 112 FQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSH 160
Q+ T + + + S+G+ +++ + +C E+ VY + E H
Sbjct: 421 IQENTKEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIPSVRQTELCH 467
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 58.9 bits (141), Expect = 3e-09
Identities = 43/152 (28%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
Query: 4 SGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTL 63
S G EIDS + V RMN+APT GFEADVG ++T +V Y F++ D +
Sbjct: 154 SSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLV-----------YPESFRELGDNV 202
Query: 64 YMVWGQGRHMDR--VLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNRR 121
M+ + +D V+ T T+ P ++ ++++ Y + +
Sbjct: 203 SMILVPFKTIDLEWVVSAITTGTISHTYIPVPA-KIRVKQDKILIYHPAFIKYVFDNWLQ 261
Query: 122 QSGSFLSTGWFTMILALELCEEIVVYGMVSDS 153
G + STG ++I ++ +C+E+ +YG +DS
Sbjct: 262 GHGRYPSTGILSVIFSMHVCDEVDLYGFGADS 293
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 58.9 bits (141), Expect = 3e-09
Identities = 43/152 (28%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
Query: 4 SGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTL 63
S G EIDS + V RMN+APT GFEADVG ++T +V Y F++ D +
Sbjct: 154 SSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLV-----------YPESFRELGDNV 202
Query: 64 YMVWGQGRHMDR--VLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNRR 121
M+ + +D V+ T T+ P ++ ++++ Y + +
Sbjct: 203 SMILVPFKTIDLEWVVSAITTGTISHTYIPVPA-KIRVKQDKILIYHPAFIKYVFDNWLQ 261
Query: 122 QSGSFLSTGWFTMILALELCEEIVVYGMVSDS 153
G + STG ++I ++ +C+E+ +YG +DS
Sbjct: 262 GHGRYPSTGILSVIFSMHVCDEVDLYGFGADS 293
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 56.2 bits (134), Expect = 2e-08
Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 23/182 (12%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+ GS G EID ++ VFR N APT F+ DVG+++ L T P +L Y + +
Sbjct: 171 LTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLT----TFNPSILEKYYNNLLTIQ 226
Query: 61 DTLYMVWGQGRHMDRVL---------GGRTYRTLLQLTRMYPG-LQVYTFTERMMAYCDQ 110
D + +L RTL+ + G L+V +A+
Sbjct: 227 DRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKV------QLAWPGN 280
Query: 111 IFQ--DETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYF 168
I Q + KN+ S LSTG LA +CEEI +YG + + +PYHY+
Sbjct: 281 IMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGF-DPNTREDLPYHYY 339
Query: 169 EK 170
+K
Sbjct: 340 DK 341
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 55.1 bits (131), Expect = 5e-08
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 7/70 (10%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKA- 59
+L S LG EIDS + V R N APT G+E DVG ++T+R+++ +L N SH+F +
Sbjct: 305 ILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTNPSHHFIDSS 360
Query: 60 --RDTLYMVW 67
+D + + W
Sbjct: 361 LYKDVILVAW 370
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 47.4 bits (111), Expect = 1e-05
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 33/219 (15%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL---LRNYS---- 53
+L S G EIDS V R N AP V F ADVG +S ++ + V RN S
Sbjct: 151 LLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREK 210
Query: 54 --HYFQKARDTL-----YMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMA 106
H D++ +MV G +H++ V + L++ YP L++ + A
Sbjct: 211 FVHRLSMLNDSVLWIPAFMVKGGEKHVEWV-NALILKNKLKVRTAYPSLRL------IHA 263
Query: 107 YCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYH 166
++ R STG LA C+EI +YG + ++ + +V YH
Sbjct: 264 VRGYWLTNKVPIKRP------STGLLMYTLATRFCDEIHLYGFW--PFPKDLNGKAVKYH 315
Query: 167 YFEKGRLDECQMYLAHEQAPRSAHRFITEKAVFSRWAKK 205
Y++ D Y ++ R F T + +R A K
Sbjct: 316 YYD----DLKYRYFSNASPHRMPLEFKTLNVLHNRGALK 350
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 47.0 bits (110), Expect = 1e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 30/188 (15%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+ LG+ ID + V R+N AP GFE DVG ++TLR+ Y R
Sbjct: 207 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYE------R 260
Query: 61 DTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQV---YTFTERMM 105
D+L+++ W + + ++ G ++ + P +++ Y E
Sbjct: 261 DSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAF 320
Query: 106 AYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPY 165
F + G+ + G + +AL C+E+ V G D S P+ P
Sbjct: 321 TLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD-----MSTPNAPL 371
Query: 166 HYFEKGRL 173
HY+E R+
Sbjct: 372 HYYETVRM 379
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 47.0 bits (110), Expect = 1e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 30/188 (15%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+ LG+ ID + V R+N AP GFE DVG ++TLR+ Y R
Sbjct: 153 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYE------R 206
Query: 61 DTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQV---YTFTERMM 105
D+L+++ W + + ++ G ++ + P +++ Y E
Sbjct: 207 DSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAF 266
Query: 106 AYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPY 165
F + G+ + G + +AL C+E+ V G D S P+ P
Sbjct: 267 TLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD-----MSTPNAPL 317
Query: 166 HYFEKGRL 173
HY+E R+
Sbjct: 318 HYYETVRM 325
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 47.0 bits (110), Expect = 1e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 30/188 (15%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+ LG+ ID + V R+N AP GFE DVG ++TLR+ Y R
Sbjct: 223 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYE------R 276
Query: 61 DTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQV---YTFTERMM 105
D+L+++ W + + ++ G ++ + P +++ Y E
Sbjct: 277 DSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAF 336
Query: 106 AYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPY 165
F + G+ + G + +AL C+E+ V G D S P+ P
Sbjct: 337 TLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD-----MSTPNAPL 387
Query: 166 HYFEKGRL 173
HY+E R+
Sbjct: 388 HYYETVRM 395
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 47.0 bits (110), Expect = 1e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 30/188 (15%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+ LG+ ID + V R+N AP GFE DVG ++TLR+ Y R
Sbjct: 184 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYE------R 237
Query: 61 DTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQV---YTFTERMM 105
D+L+++ W + + ++ G ++ + P +++ Y E
Sbjct: 238 DSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAF 297
Query: 106 AYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPY 165
F + G+ + G + +AL C+E+ V G D S P+ P
Sbjct: 298 TLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD-----MSTPNAPL 348
Query: 166 HYFEKGRL 173
HY+E R+
Sbjct: 349 HYYETVRM 356
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 47.0 bits (110), Expect = 1e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 30/188 (15%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+ LG+ ID + V R+N AP GFE DVG ++TLR+ Y R
Sbjct: 238 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYE------R 291
Query: 61 DTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQV---YTFTERMM 105
D+L+++ W + + ++ G ++ + P +++ Y E
Sbjct: 292 DSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAF 351
Query: 106 AYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPY 165
F + G+ + G + +AL C+E+ V G D S P+ P
Sbjct: 352 TLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD-----MSTPNAPL 402
Query: 166 HYFEKGRL 173
HY+E R+
Sbjct: 403 HYYETVRM 410
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 47.0 bits (110), Expect = 1e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 30/188 (15%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
+ LG+ ID + V R+N AP GFE DVG ++TLR+ Y R
Sbjct: 169 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYE------R 222
Query: 61 DTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQV---YTFTERMM 105
D+L+++ W + + ++ G ++ + P +++ Y E
Sbjct: 223 DSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAF 282
Query: 106 AYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPY 165
F + G+ + G + +AL C+E+ V G D S P+ P
Sbjct: 283 TLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD-----MSTPNAPL 333
Query: 166 HYFEKGRL 173
HY+E R+
Sbjct: 334 HYYETVRM 341
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 44.3 bits (103), Expect = 8e-05
Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 37/181 (20%)
Query: 4 SGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTL 63
S LG EID + V R N APT F+ DVG ++T+R+++ V R +D+L
Sbjct: 196 SQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR-------FLKDSL 248
Query: 64 Y-----------------MVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMA 106
Y W Q + +TYR +++P Y +M
Sbjct: 249 YNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYR------KLHPNQPFYILKPQMPW 302
Query: 107 YCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYH 166
I Q+ + + + + S+G +I+ + LC+++ +Y + K V Y+
Sbjct: 303 ELWDILQEISPEEIQPNPP--SSGMLGIIIMMTLCDQVDIY-----EFLPSKRKTDVCYY 355
Query: 167 Y 167
Y
Sbjct: 356 Y 356
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 44.3 bits (103), Expect = 8e-05
Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 37/181 (20%)
Query: 4 SGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTL 63
S LG EID + V R N APT F+ DVG ++T+R+++ V R +D+L
Sbjct: 196 SQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR-------FLKDSL 248
Query: 64 Y-----------------MVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMA 106
Y W Q + +TYR +++P Y +M
Sbjct: 249 YNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYR------KLHPNQPFYILKPQMPW 302
Query: 107 YCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYH 166
I Q+ + + + + S+G +I+ + LC+++ +Y + K V Y+
Sbjct: 303 ELWDILQEISPEEIQPNPP--SSGMLGIIIMMTLCDQVDIY-----EFLPSKRKTDVCYY 355
Query: 167 Y 167
Y
Sbjct: 356 Y 356
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 42.7 bits (99), Expect = 2e-04
Identities = 48/179 (26%), Positives = 74/179 (41%), Gaps = 28/179 (15%)
Query: 4 SGLGAEIDSAECVFRMNQAPTVG-FEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDT 62
SG G +ID A V R N P + DVG +S L T+ P ++R FQ
Sbjct: 150 SGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLV----TANPSIIRQR---FQN---- 198
Query: 63 LYMVWGQGRHMDRV-LGGRTY---RTLLQLTRMYPGLQVY-----TFTERMMAYCDQIFQ 113
++W + +D + + +Y T P L+VY + + + + F
Sbjct: 199 --LLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFL 256
Query: 114 DETGKNRRQSGSF---LSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFE 169
GK + G LSTG F + AL LCEE+ +YG S + +HY++
Sbjct: 257 RSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSV--NMHEQPISHHYYD 313
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 42.4 bits (98), Expect = 3e-04
Identities = 18/39 (46%), Positives = 25/39 (64%)
Query: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRV 39
+ LG+ ID + V R+N AP GFE DVG ++TLR+
Sbjct: 169 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 207
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 41.6 bits (96), Expect = 5e-04
Identities = 44/181 (24%), Positives = 76/181 (41%), Gaps = 29/181 (16%)
Query: 4 SGLGAEIDSAECVFRMNQAPTVGFEADVGQRST---LRVVSHTSVPLLLRN--------- 51
S +G EIDS + VFR++ A G+E DVG R++ S T L+L N
Sbjct: 377 SHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLG 436
Query: 52 ----YSHYFQKARDTLYM--------VWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYT 99
Y H+ + RD ++ V + R +R L + R L ++
Sbjct: 437 KDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREALHMDRY---LLLHP 493
Query: 100 FTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKS 159
R M ++ + +T +TG ++ AL+LC+++ YG +++ + R
Sbjct: 494 DFLRYMK--NRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSD 551
Query: 160 H 160
H
Sbjct: 552 H 552
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 39.7 bits (91), Expect = 0.002
Identities = 18/40 (45%), Positives = 26/40 (65%)
Query: 6 LGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSV 45
LG +IDS + + RMN P +G E +VG+R+T R+ SV
Sbjct: 132 LGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV 171
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 38.9 bits (89), Expect = 0.003
Identities = 44/218 (20%), Positives = 80/218 (36%), Gaps = 52/218 (23%)
Query: 3 GSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDT 62
GS G ID+ + VFR+N A GFE DVG +++ Y +++
Sbjct: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSF--------------YGFTVNTMKNS 207
Query: 63 LYMVWG-------QGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTER------------ 103
L W QG+ + + R + L G+ V ++
Sbjct: 208 LVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEA 267
Query: 104 -----------MMAYCDQIFQDETGKNRRQSGSFL-STGWFTMILALELCEEIVVYGMVS 151
++Y + F N ++ STG ++ AL C+++ YG ++
Sbjct: 268 SASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFIT 327
Query: 152 DSYCREKSHPSVPYHYFEKGRLDECQMYLAHEQAPRSA 189
+Y + HYFE+ ++ Y H+ + +A
Sbjct: 328 SNYWKFSD------HYFER-KMKPLIFYANHDLSLEAA 358
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 38.9 bits (89), Expect = 0.003
Identities = 16/36 (44%), Positives = 24/36 (66%)
Query: 4 SGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRV 39
S LG I+ + V R+N AP G+E DVG ++T+R+
Sbjct: 128 SSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRL 163
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 37.0 bits (84), Expect = 0.013
Identities = 38/171 (22%), Positives = 77/171 (45%), Gaps = 18/171 (10%)
Query: 7 GAEIDSAECVFRMNQAPTVG-FEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTLYM 65
G EID ++ VFR N PT G DVG ++ L ++ + + L N K + L++
Sbjct: 201 GTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNL-----KEKKALFL 255
Query: 66 ----VWGQGRHMDRVLGGRTYRTLLQLT-RMYPGLQVYTFTERMMAYCDQIFQDET--GK 118
+G + L ++R + ++Y L+ ++++ + + +D +
Sbjct: 256 EDIATYGDAFFL---LPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKYLKDLALFWR 312
Query: 119 NRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFE 169
+ + LSTG +A+ELC+ + +YG + + V +HY++
Sbjct: 313 TKGVTAYRLSTGLMITSVAVELCKNVKLYGFW--PFSKTVEDIPVSHHYYD 361
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 37.0 bits (84), Expect = 0.013
Identities = 43/175 (24%), Positives = 75/175 (42%), Gaps = 20/175 (11%)
Query: 4 SGLGAEIDSAECVFRMNQAP-TVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDT 62
S G EI+SA+ VFR N P + + DVG ++ + V+ P ++ H +K R
Sbjct: 176 SRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVN----PSIITERFHKLEKWRRP 231
Query: 63 LYMVWGQGRHMDRVLGG--RTYRTLLQLTRMY------PGLQVYTFTERMMAYCDQIFQD 114
Y V + +L T T + + Y VY F + + + +
Sbjct: 232 FYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLS 291
Query: 115 ETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFE 169
+ +R +STG + ALELCEE+ ++G ++ S + +HY++
Sbjct: 292 LGVRAKR-----ISTGLILVTAALELCEEVHLFGFW--AFPMNPSGLYITHHYYD 339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,135,203
Number of Sequences: 37866
Number of extensions: 326291
Number of successful extensions: 777
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 708
Number of HSP's gapped (non-prelim): 59
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.