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Search of human proteins with 27765096
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
(340 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 706 0.0
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 706 0.0
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 359 2e-99
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 115 4e-26
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 115 4e-26
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 115 4e-26
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 115 4e-26
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 115 4e-26
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 115 4e-26
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 108 7e-24
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 96 5e-20
gi|192448440 sialyltransferase 7B [Homo sapiens] 92 9e-19
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 90 3e-18
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 90 3e-18
gi|21264332 sialyltransferase 7A [Homo sapiens] 88 1e-17
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 86 6e-17
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 82 9e-16
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 79 8e-15
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 75 6e-14
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 73 3e-13
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 73 3e-13
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 72 5e-13
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 72 9e-13
gi|21361444 sialytransferase 7F [Homo sapiens] 69 8e-12
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 66 4e-11
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 65 9e-11
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 65 9e-11
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 64 3e-10
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 64 3e-10
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 61 2e-09
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 706 bits (1821), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCT 60
MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCT
Sbjct: 1 MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCT 60
Query: 61 CTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKEL 120
CTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKEL
Sbjct: 61 CTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKEL 120
Query: 121 FRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEAD 180
FRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEAD
Sbjct: 121 FRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEAD 180
Query: 181 VGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVK 240
VGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVK
Sbjct: 181 VGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVK 240
Query: 241 QDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHY 300
QDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHY
Sbjct: 241 QDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHY 300
Query: 301 WENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR 340
WENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR
Sbjct: 301 WENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR 340
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 706 bits (1821), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCT 60
MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCT
Sbjct: 1 MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCT 60
Query: 61 CTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKEL 120
CTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKEL
Sbjct: 61 CTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKEL 120
Query: 121 FRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEAD 180
FRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEAD
Sbjct: 121 FRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEAD 180
Query: 181 VGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVK 240
VGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVK
Sbjct: 181 VGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVK 240
Query: 241 QDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHY 300
QDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHY
Sbjct: 241 QDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHY 300
Query: 301 WENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR 340
WENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR
Sbjct: 301 WENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR 340
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 359 bits (921), Expect = 2e-99
Identities = 168/341 (49%), Positives = 229/341 (67%), Gaps = 14/341 (4%)
Query: 12 LTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLK---------RLIKHR----P 58
L+ L +F+ S YSH +AT + L+ + +K RL K R
Sbjct: 10 LSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRLSKERLSGKS 69
Query: 59 CTCTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIK 118
C C C+G S WFD F+ + P+ T +N L D RWW+ LQ + K +N N+ ++
Sbjct: 70 CACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFKSHNTNEVLE 129
Query: 119 ELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFE 178
+LF++VPG +P + CRRCAVVGNSGNLR S YG ++D H+F++RMN+APT GFE
Sbjct: 130 KLFQIVPGE-NPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFE 188
Query: 179 ADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIR 238
DVG++TTHH +YPES + L NVS +LVPFK +DL W+ SA++TG I TY PV + +R
Sbjct: 189 QDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLR 248
Query: 239 VKQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWH 298
V ++K+ IY+PAF KY+ D W + HGRYPSTG+L + F++HVCDEV++YGFGADS+GNWH
Sbjct: 249 VDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWH 308
Query: 299 HYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKG 339
HYWENN AG FRKTGVHDADFE+++ LA +KI +++G
Sbjct: 309 HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRG 349
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 115 bits (289), Expect = 4e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 149 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 206
Query: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 207 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 266
Query: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 267 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 326
Query: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 327 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 385
Query: 314 GVHDADFESNVTATLASINKI 334
H+ E L I
Sbjct: 386 WTHNIQREKEFLRKLVKARVI 406
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 115 bits (289), Expect = 4e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 95 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 152
Query: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 153 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 212
Query: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 213 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 272
Query: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 273 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 331
Query: 314 GVHDADFESNVTATLASINKI 334
H+ E L I
Sbjct: 332 WTHNIQREKEFLRKLVKARVI 352
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 115 bits (289), Expect = 4e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 165 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 222
Query: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 223 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 282
Query: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 283 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 342
Query: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 343 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 401
Query: 314 GVHDADFESNVTATLASINKI 334
H+ E L I
Sbjct: 402 WTHNIQREKEFLRKLVKARVI 422
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 115 bits (289), Expect = 4e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 126 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 183
Query: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 184 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 243
Query: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 244 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 303
Query: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 304 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 362
Query: 314 GVHDADFESNVTATLASINKI 334
H+ E L I
Sbjct: 363 WTHNIQREKEFLRKLVKARVI 383
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 115 bits (289), Expect = 4e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 180 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 237
Query: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 238 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 297
Query: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 298 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 357
Query: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 358 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 416
Query: 314 GVHDADFESNVTATLASINKI 334
H+ E L I
Sbjct: 417 WTHNIQREKEFLRKLVKARVI 437
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 115 bits (289), Expect = 4e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 111 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 168
Query: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 169 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 228
Query: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 229 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 288
Query: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 289 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 347
Query: 314 GVHDADFESNVTATLASINKI 334
H+ E L I
Sbjct: 348 WTHNIQREKEFLRKLVKARVI 368
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 108 bits (270), Expect = 7e-24
Identities = 67/185 (36%), Positives = 101/185 (54%), Gaps = 17/185 (9%)
Query: 135 RSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPES 194
+S+ CRRC VVGN LR SS G I+ +D V+R+N AP AG+E DVG+KTT L YPES
Sbjct: 109 QSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPES 168
Query: 195 FR-----ELGDNVSMILVPFKTIDLEWVVSAIT-TGTISHTYIPVPAKI-RVKQDKILIY 247
E + ++LV FK +D W+ + ++ + + P I V +I I
Sbjct: 169 AHFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRIL 228
Query: 248 HPAFIKYVFDNWL-------QGHGRYPSTGILSVIFSMHVCDEVDLYGFG---ADSKGNW 297
+P F++ D L + + P+TG+L++ ++H+CD V + GFG A +K
Sbjct: 229 NPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQT 288
Query: 298 HHYWE 302
HY+E
Sbjct: 289 IHYYE 293
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 95.9 bits (237), Expect = 5e-20
Identities = 69/228 (30%), Positives = 105/228 (46%), Gaps = 26/228 (11%)
Query: 116 TIKELFRVVPGNV---DPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKA 172
T E FR+ + D E ++ C++C VVGN G L+ + G +IDS+D ++RMN
Sbjct: 89 TSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNG 148
Query: 173 PTAGFEADVGTKTTHHLVYPESF----RELGDNVSMILVPFKTIDLEWVVSAITTGTISH 228
P G E +VG +TT L YPES N ++IL FK DL W++ + I+
Sbjct: 149 PVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINT 208
Query: 229 ---------TYIPVPAKIRVKQDKIL---IYHPAFIKYVFDNWLQGHGRYPSTGILSVIF 276
I P +IR+ I+ Y VF ++P+TGI+++
Sbjct: 209 NGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPK--NQKPKHPTTGIIAITL 266
Query: 277 SMHVCDEVDLYGFG---ADSKGNWHHYWENNPSAGAFRKTGVHDADFE 321
+ ++C EV L GF +D K H+Y N + K H+ E
Sbjct: 267 AFYICHEVHLAGFKYNFSDLKSPLHYY--GNATMSLMNKNAYHNVTAE 312
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 91.7 bits (226), Expect = 9e-19
Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 38/232 (16%)
Query: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRE- 197
C RCAVVGN G L S GP ID+HD+V R+N A GFE DVGTKT+ + + +
Sbjct: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNS 207
Query: 198 -------------LGDNVSMILVPFKTIDLEWVVSAI---------TTGTISHTYIPVPA 235
G ++ I +P D + SAI G H Y A
Sbjct: 208 LVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEA 267
Query: 236 KIRVKQDKILIYHPAFIKYVFDNWLQ--------GHGRYPSTGILSVIFSMHVCDEVDLY 287
K + HP FI Y+ + +L+ G PSTG L ++ ++H CD+V Y
Sbjct: 268 ----SASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAY 323
Query: 288 GFGADSKGNW-HHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFK 338
GF + + HY+E F HD E+ + L +++++
Sbjct: 324 GFITSNYWKFSDHYFERKMKPLIFYAN--HDLSLEAALWRDLHKAGILQLYQ 373
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 89.7 bits (221), Expect = 3e-18
Identities = 56/173 (32%), Positives = 85/173 (49%), Gaps = 19/173 (10%)
Query: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPE----S 194
CRRC V+G+ G L G ++ D V+R+N AP G+ VG KTT + YPE S
Sbjct: 169 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLS 228
Query: 195 FRELGDNVSMILVPFKTIDLEWVVSAITTGTIS-----HTYIPVPAKIRVKQDKILIYHP 249
E N + V FK++D W+ + + T+ + V KI ++ I +P
Sbjct: 229 DLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNP 288
Query: 250 AFIK-YVFD--NWLQGHGRY-------PSTGILSVIFSMHVCDEVDLYGFGAD 292
IK FD + + R+ P+ G+++V+ + H+CDEV L GFG D
Sbjct: 289 VIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYD 341
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 89.7 bits (221), Expect = 3e-18
Identities = 56/173 (32%), Positives = 85/173 (49%), Gaps = 19/173 (10%)
Query: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPE----S 194
CRRC V+G+ G L G ++ D V+R+N AP G+ VG KTT + YPE S
Sbjct: 192 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLS 251
Query: 195 FRELGDNVSMILVPFKTIDLEWVVSAITTGTIS-----HTYIPVPAKIRVKQDKILIYHP 249
E N + V FK++D W+ + + T+ + V KI ++ I +P
Sbjct: 252 DLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNP 311
Query: 250 AFIK-YVFD--NWLQGHGRY-------PSTGILSVIFSMHVCDEVDLYGFGAD 292
IK FD + + R+ P+ G+++V+ + H+CDEV L GFG D
Sbjct: 312 VIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYD 364
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 87.8 bits (216), Expect = 1e-17
Identities = 68/233 (29%), Positives = 111/233 (47%), Gaps = 32/233 (13%)
Query: 136 SVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHH------- 188
S+ C CAVVGN G L S G EIDSHD+V R++ A G+E DVGT+T+ +
Sbjct: 359 SLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSL 418
Query: 189 -----LVYPESFRE--LGDNVSMILVPFKTIDLEWVVSAITTGTISHTYI------PVPA 235
++ F+ LG +V + T D EW+ + + T+ + P A
Sbjct: 419 TQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEA 478
Query: 236 -KIRVKQDKILIYHPAFIKYVFDNWLQ------GHGRY--PSTGILSVIFSMHVCDEVDL 286
+ + D+ L+ HP F++Y+ + +L+ H R P+TG L ++ ++ +CD+V
Sbjct: 479 FREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSA 538
Query: 287 YGFGADSKGNW-HHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFK 338
YGF + + HY++ + F HD E V L IR+++
Sbjct: 539 YGFITEGHERFSDHYYDTSWKRLIFYIN--HDFKLEREVWKRLHDEGIIRLYQ 589
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 85.5 bits (210), Expect = 6e-17
Identities = 50/144 (34%), Positives = 75/144 (52%), Gaps = 10/144 (6%)
Query: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 111 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 168
Query: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 169 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 228
Query: 207 VPFKTIDLEWVVSAITTGTISHTY 230
FK D +W+ + +S T+
Sbjct: 229 AGFKWQDFKWLKYIVYKERVSWTH 252
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 81.6 bits (200), Expect = 9e-16
Identities = 66/202 (32%), Positives = 95/202 (47%), Gaps = 22/202 (10%)
Query: 119 ELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFE 178
+L ++P V PM +R + CAVVGNSG L +S G EIDSH+FV+R N AP F
Sbjct: 123 DLHSLLP-EVSPMKNRRF---KTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFA 178
Query: 179 ADVGTKTTHHLVYPE-------SFRELGDNVSMI-LVPFKTIDLEWVVSAITTGTISHTY 230
ADVGTK+ + P FR D + + + W+ + + G H
Sbjct: 179 ADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVE 238
Query: 231 IPVPAKIRVKQDKILIYHPA--FIKYVFDNWLQGHG--RYPSTGILSVIFSMHVCDEVDL 286
V A I + K+ +P+ I V WL + PSTG+L + CDE+ L
Sbjct: 239 W-VNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHL 297
Query: 287 YGF-----GADSKGNWHHYWEN 303
YGF + K +HY+++
Sbjct: 298 YGFWPFPKDLNGKAVKYHYYDD 319
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 78.6 bits (192), Expect = 8e-15
Identities = 70/244 (28%), Positives = 109/244 (44%), Gaps = 27/244 (11%)
Query: 67 QRKLSAWFDERFNQT---------MQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTI 117
Q K S W +FN+T +Q + +N L ++ R + + + +I
Sbjct: 84 QEKPSKW---KFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSI 140
Query: 118 KELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGF 177
FR + +V P++ K CAVVGNSG L S G EID DFV R N APT F
Sbjct: 141 SNNFRSLLPDVSPIMNKHY---NICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAF 197
Query: 178 EADVGTKTTHHLVYPESFRELGDNVSMI------LVPFKTID--LEWVVSAI--TTGTIS 227
+ DVG KT P + +N+ I + K +D + W+ + T+ T++
Sbjct: 198 QRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVT 257
Query: 228 HTYIPVPAKIRVKQDKILIYHPAFIKYVFDNWLQGH--GRYPSTGILSVIFSMHVCDEVD 285
T + + R + L + +++V W H + STGIL + +C+E+
Sbjct: 258 RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIH 317
Query: 286 LYGF 289
LYGF
Sbjct: 318 LYGF 321
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 75.5 bits (184), Expect = 6e-14
Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 14/167 (8%)
Query: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLV-------- 190
CR CAVV +SG + S G EIDS + V RMN+APT GFEADVG ++T +V
Sbjct: 73 CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL 132
Query: 191 ---YPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPA-KIRVKQDKILI 246
Y F++ D + M+ + +D V+ T T+ P ++ ++++
Sbjct: 133 LRNYSHYFQKARDTLYMVWGQGRHMDR--VLGGRTYRTLLQLTRMYPGLQVYTFTERMMA 190
Query: 247 YHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADS 293
Y + + G + STG ++I ++ +C+E+ +YG +DS
Sbjct: 191 YCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDS 237
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 73.2 bits (178), Expect = 3e-13
Identities = 56/187 (29%), Positives = 85/187 (45%), Gaps = 27/187 (14%)
Query: 122 RVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADV 181
R+VP P+ + G R CAVV ++G + SS G EIDSHD VLR N APT G+E DV
Sbjct: 278 RLVPAV--PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
Query: 182 GTKTT-------------HHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISH 228
G KTT HH + ++++ ILV + ++ +
Sbjct: 336 GNKTTIRIINSQILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYN 389
Query: 229 TYIP-VPAKIRVKQDKILIYHPAFIKYVFDNWLQG-----HGRYPSTGILSVIFSMHVCD 282
+ P + + R I HP FI ++D + PS+G + ++ M +C
Sbjct: 390 LFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCR 449
Query: 283 EVDLYGF 289
EV +Y +
Sbjct: 450 EVHVYEY 456
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 73.2 bits (178), Expect = 3e-13
Identities = 56/187 (29%), Positives = 85/187 (45%), Gaps = 27/187 (14%)
Query: 122 RVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADV 181
R+VP P+ + G R CAVV ++G + SS G EIDSHD VLR N APT G+E DV
Sbjct: 278 RLVPAV--PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
Query: 182 GTKTT-------------HHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISH 228
G KTT HH + ++++ ILV + ++ +
Sbjct: 336 GNKTTIRIINSQILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYN 389
Query: 229 TYIP-VPAKIRVKQDKILIYHPAFIKYVFDNWLQG-----HGRYPSTGILSVIFSMHVCD 282
+ P + + R I HP FI ++D + PS+G + ++ M +C
Sbjct: 390 LFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCR 449
Query: 283 EVDLYGF 289
EV +Y +
Sbjct: 450 EVHVYEY 456
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 72.4 bits (176), Expect = 5e-13
Identities = 59/180 (32%), Positives = 86/180 (47%), Gaps = 19/180 (10%)
Query: 141 RCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAG-FEADVGTKTTHHLVYPE----SF 195
+CAVVGN G L +S G EID DFV R N PT G DVG+KT + P +
Sbjct: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
Query: 196 RELGDNVSMILVPFKTI-DLEWVVSAIT----TGTISHTYIPVPAKIRVKQDKILIYHPA 250
L + ++ L T D +++ A + TGT Y + + K+L +HP
Sbjct: 245 GNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES--KARQKVLFFHPK 302
Query: 251 FIKYVFDNW-LQGHGRYP-STGILSVIFSMHVCDEVDLYGFGADSK-----GNWHHYWEN 303
++K + W +G Y STG++ ++ +C V LYGF SK HHY++N
Sbjct: 303 YLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYYDN 362
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 71.6 bits (174), Expect = 9e-13
Identities = 62/217 (28%), Positives = 101/217 (46%), Gaps = 21/217 (9%)
Query: 103 RLQREKKPNNLNDTIKELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDS 162
+L+ E + + +E+FR+ P ++ P + ++CAVVGN G L+ S G EI+S
Sbjct: 129 KLKYEVDTSGIYHINQEIFRMFPKDM-PYYRSQF---KKCAVVGNGGILKNSRCGREINS 184
Query: 163 HDFVLRMNKAP-TAGFEADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAI 221
DFV R N P + + DVG KT V P E + PF + + +++
Sbjct: 185 ADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASV 244
Query: 222 TTGTISHTYIPVPAKIRVK--------QDKILIYHPAFIKYVFDNWLQ--GHGRYPSTGI 271
+T IRVK + +HP ++ V WL + STG+
Sbjct: 245 LLPAFYNTR-NTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGL 303
Query: 272 LSVIFSMHVCDEVDLYGFGA---DSKGNW--HHYWEN 303
+ V ++ +C+EV L+GF A + G + HHY++N
Sbjct: 304 ILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDN 340
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 68.6 bits (166), Expect = 8e-12
Identities = 58/202 (28%), Positives = 95/202 (47%), Gaps = 33/202 (16%)
Query: 106 REKKPNNLNDTIKELFRVVPGNVDPMLEKRSVG--CRRCAVVGNSGNLRESSYGPEIDSH 163
R ++P NL + + G V P+L +++ C +C +V +S +L + GPEI+
Sbjct: 76 RSRRPVNLKK-----WSITDGYV-PILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERA 129
Query: 164 DFVLRMNKAPTAGFEADVGTKTTHHLVYPES-FRELGDNVSMILVPFKTIDLEWVVSAIT 222
+ +RMN APT G+ ADVG KTT+ +V S FR L + +T+ + W
Sbjct: 130 ECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFW------ 183
Query: 223 TGTISHTYIPVPAKIRVKQDKILIYHPAFIKYV--------FDNWLQGH--------GRY 266
G S P + +RV Q L++ P Y FD+ +G +
Sbjct: 184 -GPPSKMQKPQGSLVRVIQRAGLVF-PNMEAYAVSPGRMRQFDDLFRGETGKDREKSHSW 241
Query: 267 PSTGILSVIFSMHVCDEVDLYG 288
STG +++ ++ +CD V +YG
Sbjct: 242 LSTGWFTMVIAVELCDHVHVYG 263
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 66.2 bits (160), Expect = 4e-11
Identities = 35/69 (50%), Positives = 44/69 (63%), Gaps = 2/69 (2%)
Query: 122 RVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADV 181
R+VP P+ + G R CAVV ++G + SS G EIDSHD VLR N APT G+E DV
Sbjct: 278 RLVPAV--PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
Query: 182 GTKTTHHLV 190
G KTT ++
Sbjct: 336 GNKTTIRII 344
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 65.1 bits (157), Expect = 9e-11
Identities = 31/50 (62%), Positives = 37/50 (74%)
Query: 141 RCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLV 190
RCAVV ++G+L+ S G EID HD VLR N APTA F+ DVGTKTT L+
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLM 232
Score = 32.7 bits (73), Expect = 0.48
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 267 PSTGILSVIFSMHVCDEVDLYGF 289
PS+G+L +I M +CD+VD+Y F
Sbjct: 321 PSSGMLGIIIMMTLCDQVDIYEF 343
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 65.1 bits (157), Expect = 9e-11
Identities = 31/50 (62%), Positives = 37/50 (74%)
Query: 141 RCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLV 190
RCAVV ++G+L+ S G EID HD VLR N APTA F+ DVGTKTT L+
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLM 232
Score = 32.7 bits (73), Expect = 0.48
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 267 PSTGILSVIFSMHVCDEVDLYGF 289
PS+G+L +I M +CD+VD+Y F
Sbjct: 321 PSSGMLGIIIMMTLCDQVDIYEF 343
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 63.5 bits (153), Expect = 3e-10
Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 16/174 (9%)
Query: 133 EKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYP 192
E + C CA+V NSG + G EID + RMN APT G+E DVG T +V
Sbjct: 71 EPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSH 130
Query: 193 ES-----------FRELGDNVSMILVPFKTI--DLEWVVSAITTGTISHTYIPVPAKIRV 239
S F+E + +I PF+ + D +V + T+ I A+I V
Sbjct: 131 TSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVG---IYPNAQIYV 187
Query: 240 KQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADS 293
+K + Y K G Y STG + + +M C + +YG D+
Sbjct: 188 TTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDT 241
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 63.5 bits (153), Expect = 3e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 35/189 (18%)
Query: 140 RRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAP-TAGFEADVGTKTTHHLVYPESFREL 198
++CAVVGN G L++S G +ID +FV+R N P ++ + DVG+K+ P R+
Sbjct: 136 KKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQR 195
Query: 199 GDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPA---------KIRV--------KQ 241
N +L KT +H+YI +PA +RV
Sbjct: 196 FQN---LLWSRKTF-------VDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGAN 245
Query: 242 DKILIYHPAFIKYVFDNWLQG--HGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNW-- 297
+L +P F++ + W H + STG+ V ++ +C+EV +YGF S
Sbjct: 246 QTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQ 305
Query: 298 ---HHYWEN 303
HHY++N
Sbjct: 306 PISHHYYDN 314
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 60.8 bits (146), Expect = 2e-09
Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 21/164 (12%)
Query: 142 CAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDN 201
CA+VGNSG L S G EID+H FV+R N AP + DVG KT + P + ++
Sbjct: 157 CAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRAFED 216
Query: 202 V------SMILVPFKTID--LEWVVSAITTGT------ISHTYIPVPAKIRVKQDKILIY 247
+ +L +++ + W+ + + G ++ + +R + +
Sbjct: 217 LVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKHHVNVRTAYPSLRLL 276
Query: 248 HPAFIKYVFDNWLQG--HGRYPSTGILSVIFSMHVCDEVDLYGF 289
H V WL H + P+TG+L + C ++ LYGF
Sbjct: 277 HA-----VRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGF 315
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,526,038
Number of Sequences: 37866
Number of extensions: 539172
Number of successful extensions: 1128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1055
Number of HSP's gapped (non-prelim): 49
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.