Search of human proteins with 25952105

Search of human proteins with 25952105

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25952105 calcium-activated potassium channel beta 3 subunit
isoform c [Homo sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25952105 calcium-activated potassium channel beta 3 subunit i...   574   e-164
gi|25952095 calcium-activated potassium channel beta 3 subunit i...   537   e-153
gi|25952099 calcium-activated potassium channel beta 3 subunit i...   537   e-153
gi|25952102 calcium-activated potassium channel beta 3 subunit i...   535   e-152
gi|31317295 calcium-activated potassium channel beta 2 subunit [...   185   4e-47
gi|5031823 calcium-activated potassium channel beta 2 subunit [H...   185   4e-47
gi|26051275 calcium-activated potassium channel beta 4 subunit [...   139   3e-33
gi|4758626 potassium large conductance calcium-activated channel...    94   2e-19
gi|226529863 T-cell immunoglobulin and mucin domain containing 4...    33   0.35 
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s...    32   0.46 
gi|21314682 transient receptor potential cation channel, subfami...    28   8.7  

>gi|25952105 calcium-activated potassium channel beta 3 subunit
           isoform c [Homo sapiens]
          Length = 275

 Score =  574 bits (1479), Expect = e-164
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MFPLLYELTAVSPSPFPQRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFA 60
           MFPLLYELTAVSPSPFPQRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFA
Sbjct: 1   MFPLLYELTAVSPSPFPQRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFA 60

Query: 61  MMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYP 120
           MMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYP
Sbjct: 61  MMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYP 120

Query: 121 CLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGT 180
           CLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGT
Sbjct: 121 CLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGT 180

Query: 181 PFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKY 240
           PFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKY
Sbjct: 181 PFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKY 240

Query: 241 STVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS 275
           STVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS
Sbjct: 241 STVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS 275


>gi|25952095 calcium-activated potassium channel beta 3 subunit
           isoform d [Homo sapiens]
          Length = 279

 Score =  537 bits (1384), Expect = e-153
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 19  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 78
           RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK
Sbjct: 23  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 82

Query: 79  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 138
           PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH
Sbjct: 83  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 142

Query: 139 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 198
           YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI
Sbjct: 143 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 202

Query: 199 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 258
           KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH
Sbjct: 203 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 262

Query: 259 QFKLCIMRRSKGRAEKS 275
           QFKLCIMRRSKGRAEKS
Sbjct: 263 QFKLCIMRRSKGRAEKS 279


>gi|25952099 calcium-activated potassium channel beta 3 subunit
           isoform a [Homo sapiens]
          Length = 277

 Score =  537 bits (1384), Expect = e-153
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 19  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 78
           RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK
Sbjct: 21  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 80

Query: 79  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 138
           PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH
Sbjct: 81  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 140

Query: 139 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 198
           YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI
Sbjct: 141 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 200

Query: 199 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 258
           KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH
Sbjct: 201 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 260

Query: 259 QFKLCIMRRSKGRAEKS 275
           QFKLCIMRRSKGRAEKS
Sbjct: 261 QFKLCIMRRSKGRAEKS 277


>gi|25952102 calcium-activated potassium channel beta 3 subunit
           isoform b [Homo sapiens]
          Length = 257

 Score =  535 bits (1379), Expect = e-152
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 20  TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 79
           TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
Sbjct: 2   TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 61

Query: 80  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 139
           FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
Sbjct: 62  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 121

Query: 140 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 199
           NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
Sbjct: 122 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 181

Query: 200 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 259
           KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
Sbjct: 182 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 241

Query: 260 FKLCIMRRSKGRAEKS 275
           FKLCIMRRSKGRAEKS
Sbjct: 242 FKLCIMRRSKGRAEKS 257


>gi|31317295 calcium-activated potassium channel beta 2 subunit
           [Homo sapiens]
          Length = 235

 Score =  185 bits (469), Expect = 4e-47
 Identities = 93/212 (43%), Positives = 135/212 (63%), Gaps = 4/212 (1%)

Query: 35  DGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTA 93
           D D LD  K + +  AGEDRA++LG AMM  S++M+FLLG T+L+ +M S+  EES CT 
Sbjct: 27  DHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTL 86

Query: 94  IHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYT 153
           ++  I + + +C+F+CG  C    +YPCLQV+VNL+  G+K LL++ EE ++IN KC Y 
Sbjct: 87  LNASITETF-NCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYI 145

Query: 154 PKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWP 213
           PKC ++  + ++    + E F  +    FSC+  P    + VIL K Y    +FH LFWP
Sbjct: 146 PKCGKNFEESMSLVNVVMENF--RKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWP 203

Query: 214 SLTLLGGALIVGMVRLTQHLSLLCEKYSTVVR 245
           +  + GG  IV MV+LTQ+LSLLCE+   + R
Sbjct: 204 TCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 235


>gi|5031823 calcium-activated potassium channel beta 2 subunit [Homo
           sapiens]
          Length = 235

 Score =  185 bits (469), Expect = 4e-47
 Identities = 93/212 (43%), Positives = 135/212 (63%), Gaps = 4/212 (1%)

Query: 35  DGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTA 93
           D D LD  K + +  AGEDRA++LG AMM  S++M+FLLG T+L+ +M S+  EES CT 
Sbjct: 27  DHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTL 86

Query: 94  IHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYT 153
           ++  I + + +C+F+CG  C    +YPCLQV+VNL+  G+K LL++ EE ++IN KC Y 
Sbjct: 87  LNASITETF-NCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYI 145

Query: 154 PKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWP 213
           PKC ++  + ++    + E F  +    FSC+  P    + VIL K Y    +FH LFWP
Sbjct: 146 PKCGKNFEESMSLVNVVMENF--RKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWP 203

Query: 214 SLTLLGGALIVGMVRLTQHLSLLCEKYSTVVR 245
           +  + GG  IV MV+LTQ+LSLLCE+   + R
Sbjct: 204 TCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 235


>gi|26051275 calcium-activated potassium channel beta 4 subunit
           [Homo sapiens]
          Length = 210

 Score =  139 bits (349), Expect = 3e-33
 Identities = 61/189 (32%), Positives = 109/189 (57%), Gaps = 1/189 (0%)

Query: 51  EDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCG 110
           ED+++ LG  ++   V+  F+ G   L P +  +Q  E+ CT +    + +  +C FTCG
Sbjct: 14  EDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCG 73

Query: 111 VHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDI 170
             C G  +YPC+QV+VN S    +ALLH +E  +  NPKC Y P C ++    L S ++ 
Sbjct: 74  ADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNW 133

Query: 171 KEFFDHKNGT-PFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRL 229
           ++++  + G+ PF+C+++   + +DV+L + +D++ + HC  WP +T + G LIV +   
Sbjct: 134 QQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTIC 193

Query: 230 TQHLSLLCE 238
            + L++  E
Sbjct: 194 AKSLAVKAE 202


>gi|4758626 potassium large conductance calcium-activated channel,
           subfamily M, beta member 1 [Homo sapiens]
          Length = 191

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 15/189 (7%)

Query: 50  GEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTC 109
           GE RA+ LG  M+  +V+ +++L TT+L  +  S+  +ES C  I T+I D         
Sbjct: 12  GETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQ-------- 63

Query: 110 GVHCHGQG--KYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSA 167
                G+   +YPCL  +VN+S  G+ A+L++ E+    N +C Y P    +        
Sbjct: 64  -EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120

Query: 168 LDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMV 227
             ++  F  +    F CF +P      V+  + Y   A+   LFWP+  L GG LI+ MV
Sbjct: 121 EKVRAKFQEQQ--VFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178

Query: 228 RLTQHLSLL 236
           +  Q+LS+L
Sbjct: 179 KSNQYLSIL 187


>gi|226529863 T-cell immunoglobulin and mucin domain containing 4
           isoform 1 [Homo sapiens]
          Length = 378

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 11/85 (12%)

Query: 12  SPSPFPQRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFL 71
           SP P    TA P   K  +T   DG P+ +   +P S    + +M+    +GF +   F+
Sbjct: 277 SPQPGASDTAVPEQNKTTKTGQMDGIPMSMKNEMPIS----QLLMIIAPSLGFVLFALFV 332

Query: 72  LGTTILKPFMLSIQREESTCTAIHT 96
                   F+L  +  E+ C+  HT
Sbjct: 333 -------AFLLRGKLMETYCSQKHT 350


>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
           sapiens]
          Length = 508

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 18/48 (37%), Positives = 23/48 (47%)

Query: 7   ELTAVSPSPFPQRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRA 54
           E+ AV    FP    FPAS  +   DY+    LD  K+   S G+D A
Sbjct: 431 EVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGA 478


>gi|21314682 transient receptor potential cation channel, subfamily
           V, member 6 [Homo sapiens]
          Length = 725

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 3/44 (6%)

Query: 44  RLPSSAGEDRAVMLGFAM-MGFSVLMFFLLGTTILKPFMLSIQR 86
           RL S++GE   V + FA+ +G+  +M+F  G  +L PF + IQ+
Sbjct: 443 RLISASGE--VVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,136,204
Number of Sequences: 37866
Number of extensions: 504254
Number of successful extensions: 1367
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1350
Number of HSP's gapped (non-prelim): 11
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.