Search of human proteins with 25952099

Search of human proteins with 25952099

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25952099 calcium-activated potassium channel beta 3 subunit
isoform a [Homo sapiens]
         (277 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25952099 calcium-activated potassium channel beta 3 subunit i...   576   e-165
gi|25952095 calcium-activated potassium channel beta 3 subunit i...   537   e-153
gi|25952105 calcium-activated potassium channel beta 3 subunit i...   537   e-153
gi|25952102 calcium-activated potassium channel beta 3 subunit i...   535   e-152
gi|31317295 calcium-activated potassium channel beta 2 subunit [...   185   3e-47
gi|5031823 calcium-activated potassium channel beta 2 subunit [H...   185   3e-47
gi|26051275 calcium-activated potassium channel beta 4 subunit [...   139   4e-33
gi|4758626 potassium large conductance calcium-activated channel...    94   2e-19
gi|24307901 interferon-induced protein 35 [Homo sapiens]               30   3.0  
gi|21314682 transient receptor potential cation channel, subfami...    28   8.8  

>gi|25952099 calcium-activated potassium channel beta 3 subunit
           isoform a [Homo sapiens]
          Length = 277

 Score =  576 bits (1485), Expect = e-165
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MQPFSIPVQITLQGSRRRQGRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLG 60
           MQPFSIPVQITLQGSRRRQGRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLG
Sbjct: 1   MQPFSIPVQITLQGSRRRQGRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLG 60

Query: 61  FAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGK 120
           FAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGK
Sbjct: 61  FAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGK 120

Query: 121 YPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKN 180
           YPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKN
Sbjct: 121 YPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKN 180

Query: 181 GTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCE 240
           GTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCE
Sbjct: 181 GTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCE 240

Query: 241 KYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS 277
           KYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS
Sbjct: 241 KYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS 277


>gi|25952095 calcium-activated potassium channel beta 3 subunit
           isoform d [Homo sapiens]
          Length = 279

 Score =  537 bits (1384), Expect = e-153
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 21  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 80
           RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK
Sbjct: 23  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 82

Query: 81  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 140
           PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH
Sbjct: 83  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 142

Query: 141 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 200
           YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI
Sbjct: 143 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 202

Query: 201 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 260
           KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH
Sbjct: 203 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 262

Query: 261 QFKLCIMRRSKGRAEKS 277
           QFKLCIMRRSKGRAEKS
Sbjct: 263 QFKLCIMRRSKGRAEKS 279


>gi|25952105 calcium-activated potassium channel beta 3 subunit
           isoform c [Homo sapiens]
          Length = 275

 Score =  537 bits (1384), Expect = e-153
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 21  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 80
           RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK
Sbjct: 19  RTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 78

Query: 81  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 140
           PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH
Sbjct: 79  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 138

Query: 141 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 200
           YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI
Sbjct: 139 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 198

Query: 201 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 260
           KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH
Sbjct: 199 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 258

Query: 261 QFKLCIMRRSKGRAEKS 277
           QFKLCIMRRSKGRAEKS
Sbjct: 259 QFKLCIMRRSKGRAEKS 275


>gi|25952102 calcium-activated potassium channel beta 3 subunit
           isoform b [Homo sapiens]
          Length = 257

 Score =  535 bits (1379), Expect = e-152
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 22  TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 81
           TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
Sbjct: 2   TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 61

Query: 82  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 141
           FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
Sbjct: 62  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 121

Query: 142 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 201
           NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
Sbjct: 122 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 181

Query: 202 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 261
           KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
Sbjct: 182 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 241

Query: 262 FKLCIMRRSKGRAEKS 277
           FKLCIMRRSKGRAEKS
Sbjct: 242 FKLCIMRRSKGRAEKS 257


>gi|31317295 calcium-activated potassium channel beta 2 subunit
           [Homo sapiens]
          Length = 235

 Score =  185 bits (470), Expect = 3e-47
 Identities = 97/232 (41%), Positives = 142/232 (61%), Gaps = 7/232 (3%)

Query: 20  GRTAFPASGKKRETDYS---DGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVLMFFLLG 75
           GRT+      ++   Y    D D LD  K + +  AGEDRA++LG AMM  S++M+FLLG
Sbjct: 7   GRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLG 66

Query: 76  TTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQ 135
            T+L+ +M S+  EES CT ++  I + + +C+F+CG  C    +YPCLQV+VNL+  G+
Sbjct: 67  ITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQVYVNLTSSGE 125

Query: 136 KALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSE 195
           K LL++ EE ++IN KC Y PKC ++  + ++    + E F  +    FSC+  P    +
Sbjct: 126 KLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFSCYSDPEGNQK 183

Query: 196 DVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVR 247
            VIL K Y    +FH LFWP+  + GG  IV MV+LTQ+LSLLCE+   + R
Sbjct: 184 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 235


>gi|5031823 calcium-activated potassium channel beta 2 subunit [Homo
           sapiens]
          Length = 235

 Score =  185 bits (470), Expect = 3e-47
 Identities = 97/232 (41%), Positives = 142/232 (61%), Gaps = 7/232 (3%)

Query: 20  GRTAFPASGKKRETDYS---DGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVLMFFLLG 75
           GRT+      ++   Y    D D LD  K + +  AGEDRA++LG AMM  S++M+FLLG
Sbjct: 7   GRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLG 66

Query: 76  TTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQ 135
            T+L+ +M S+  EES CT ++  I + + +C+F+CG  C    +YPCLQV+VNL+  G+
Sbjct: 67  ITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQVYVNLTSSGE 125

Query: 136 KALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSE 195
           K LL++ EE ++IN KC Y PKC ++  + ++    + E F  +    FSC+  P    +
Sbjct: 126 KLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFSCYSDPEGNQK 183

Query: 196 DVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVR 247
            VIL K Y    +FH LFWP+  + GG  IV MV+LTQ+LSLLCE+   + R
Sbjct: 184 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 235


>gi|26051275 calcium-activated potassium channel beta 4 subunit
           [Homo sapiens]
          Length = 210

 Score =  139 bits (349), Expect = 4e-33
 Identities = 61/189 (32%), Positives = 109/189 (57%), Gaps = 1/189 (0%)

Query: 53  EDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCG 112
           ED+++ LG  ++   V+  F+ G   L P +  +Q  E+ CT +    + +  +C FTCG
Sbjct: 14  EDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCG 73

Query: 113 VHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDI 172
             C G  +YPC+QV+VN S    +ALLH +E  +  NPKC Y P C ++    L S ++ 
Sbjct: 74  ADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNW 133

Query: 173 KEFFDHKNGT-PFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRL 231
           ++++  + G+ PF+C+++   + +DV+L + +D++ + HC  WP +T + G LIV +   
Sbjct: 134 QQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTIC 193

Query: 232 TQHLSLLCE 240
            + L++  E
Sbjct: 194 AKSLAVKAE 202


>gi|4758626 potassium large conductance calcium-activated channel,
           subfamily M, beta member 1 [Homo sapiens]
          Length = 191

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 15/189 (7%)

Query: 52  GEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTC 111
           GE RA+ LG  M+  +V+ +++L TT+L  +  S+  +ES C  I T+I D         
Sbjct: 12  GETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQ-------- 63

Query: 112 GVHCHGQG--KYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSA 169
                G+   +YPCL  +VN+S  G+ A+L++ E+    N +C Y P    +        
Sbjct: 64  -EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120

Query: 170 LDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMV 229
             ++  F  +    F CF +P      V+  + Y   A+   LFWP+  L GG LI+ MV
Sbjct: 121 EKVRAKFQEQQ--VFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178

Query: 230 RLTQHLSLL 238
           +  Q+LS+L
Sbjct: 179 KSNQYLSIL 187


>gi|24307901 interferon-induced protein 35 [Homo sapiens]
          Length = 288

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 24/83 (28%)

Query: 1   MQPFSIPVQITLQG------SRRRQGRTAFPASGKKRETDYSD------------GDPLD 42
           +QP  +P+  T+Q       S RR   T FPAS +  E +  D            G  +D
Sbjct: 113 VQPLELPMVTTIQVMVSSQLSGRRVLVTGFPASLRLSEEELLDKLEIFFGKTRNGGGDVD 172

Query: 43  VHKRLPSSAGEDRAVMLGFAMMG 65
           V + LP S      VMLGFA  G
Sbjct: 173 VRELLPGS------VMLGFARDG 189


>gi|21314682 transient receptor potential cation channel, subfamily
           V, member 6 [Homo sapiens]
          Length = 725

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 3/44 (6%)

Query: 46  RLPSSAGEDRAVMLGFAM-MGFSVLMFFLLGTTILKPFMLSIQR 88
           RL S++GE   V + FA+ +G+  +M+F  G  +L PF + IQ+
Sbjct: 443 RLISASGE--VVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,941,428
Number of Sequences: 37866
Number of extensions: 489663
Number of successful extensions: 1297
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1282
Number of HSP's gapped (non-prelim): 10
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.