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Search of human proteins with 25777598
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
sapiens]
(1214 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ... 2456 0.0
gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo ... 2349 0.0
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 1518 0.0
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] 1410 0.0
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 770 0.0
gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens] 210 8e-54
gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens] 210 8e-54
gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens] 207 4e-53
gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 206 1e-52
gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 206 1e-52
gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 206 1e-52
gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 206 1e-52
gi|4503313 diacylglycerol kinase epsilon [Homo sapiens] 189 1e-47
gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens] 164 6e-40
gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens] 154 6e-37
gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens] 151 4e-36
gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens] 151 4e-36
gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens] 150 7e-36
gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens] 150 7e-36
gi|4758156 diacylglycerol kinase, iota [Homo sapiens] 142 2e-33
gi|40806175 diacylglycerol kinase, theta [Homo sapiens] 132 2e-30
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 68 5e-11
gi|28557781 protein kinase C, eta [Homo sapiens] 66 2e-10
gi|47157325 protein kinase C, delta [Homo sapiens] 64 7e-10
gi|31377782 protein kinase C, delta [Homo sapiens] 64 7e-10
gi|4885563 protein kinase C, epsilon [Homo sapiens] 63 2e-09
gi|120659787 protein kinase D2 isoform B [Homo sapiens] 59 2e-08
gi|120659785 protein kinase D2 isoform A [Homo sapiens] 59 2e-08
gi|120659782 protein kinase D2 isoform A [Homo sapiens] 59 2e-08
gi|19923468 protein kinase D2 isoform A [Homo sapiens] 59 2e-08
>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
sapiens]
Length = 1214
Score = 2456 bits (6365), Expect = 0.0
Identities = 1214/1214 (100%), Positives = 1214/1214 (100%)
Query: 1 MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGML 60
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGML
Sbjct: 1 MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGML 60
Query: 61 TKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITP 120
TKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITP
Sbjct: 61 TKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITP 120
Query: 121 CRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVC 180
CRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVC
Sbjct: 121 CRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVC 180
Query: 181 REALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLE 240
REALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLE
Sbjct: 181 REALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLE 240
Query: 241 GNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTA 300
GNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTA
Sbjct: 241 GNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTA 300
Query: 301 LNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPH 360
LNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPH
Sbjct: 301 LNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPH 360
Query: 361 LGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGS 420
LGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGS
Sbjct: 361 LGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGS 420
Query: 421 ACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFY 480
ACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFY
Sbjct: 421 ACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFY 480
Query: 481 EDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCS 540
EDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCS
Sbjct: 481 EDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCS 540
Query: 541 VLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARP 600
VLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARP
Sbjct: 541 VLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARP 600
Query: 601 QIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVC 660
QIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVC
Sbjct: 601 QIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVC 660
Query: 661 PPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKIL 720
PPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKIL
Sbjct: 661 PPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKIL 720
Query: 721 YPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDF 780
YPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDF
Sbjct: 721 YPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDF 780
Query: 781 NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAV 840
NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAV
Sbjct: 781 NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAV 840
Query: 841 LNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCR 900
LNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCR
Sbjct: 841 LNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCR 900
Query: 901 TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL 960
TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL
Sbjct: 901 TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL 960
Query: 961 PRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSM 1020
PRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSM
Sbjct: 961 PRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSM 1020
Query: 1021 DRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMD 1080
DRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMD
Sbjct: 1021 DRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMD 1080
Query: 1081 RQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGA 1140
RQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGA
Sbjct: 1081 RQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGA 1140
Query: 1141 PVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILC 1200
PVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILC
Sbjct: 1141 PVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILC 1200
Query: 1201 GIKELSRSAPAVEA 1214
GIKELSRSAPAVEA
Sbjct: 1201 GIKELSRSAPAVEA 1214
>gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo
sapiens]
Length = 1170
Score = 2349 bits (6087), Expect = 0.0
Identities = 1162/1163 (99%), Positives = 1163/1163 (100%)
Query: 52 KTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNV 111
+TIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNV
Sbjct: 8 QTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNV 67
Query: 112 NNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSH 171
NNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSH
Sbjct: 68 NNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSH 127
Query: 172 ARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADG 231
ARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADG
Sbjct: 128 ARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADG 187
Query: 232 IAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLC 291
IAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLC
Sbjct: 188 IAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLC 247
Query: 292 KVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQV 351
KVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQV
Sbjct: 248 KVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQV 307
Query: 352 FDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGND 411
FDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGND
Sbjct: 308 FDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGND 367
Query: 412 LARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSED 471
LARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSED
Sbjct: 368 LARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSED 427
Query: 472 SEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEE 531
SEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEE
Sbjct: 428 SEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEE 487
Query: 532 SEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRL 591
SEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRL
Sbjct: 488 SEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRL 547
Query: 592 VASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSES 651
VASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSES
Sbjct: 548 VASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSES 607
Query: 652 EEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDG 711
EEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDG
Sbjct: 608 EEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDG 667
Query: 712 LPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIG 771
LPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIG
Sbjct: 668 LPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIG 727
Query: 772 LDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIP 831
LDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIP
Sbjct: 728 LDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIP 787
Query: 832 LPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRL 891
LPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRL
Sbjct: 788 LPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRL 847
Query: 892 QHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKS 951
QHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKS
Sbjct: 848 QHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKS 907
Query: 952 WEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAH 1011
WEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAH
Sbjct: 908 WEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAH 967
Query: 1012 AVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQ 1071
AVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQ
Sbjct: 968 AVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQ 1027
Query: 1072 LGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKN 1131
LGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKN
Sbjct: 1028 LGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKN 1087
Query: 1132 KEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTK 1191
KEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTK
Sbjct: 1088 KEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTK 1147
Query: 1192 VGHMKRILCGIKELSRSAPAVEA 1214
VGHMKRILCGIKELSRSAPAVEA
Sbjct: 1148 VGHMKRILCGIKELSRSAPAVEA 1170
>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
Length = 1220
Score = 1518 bits (3929), Expect = 0.0
Identities = 794/1224 (64%), Positives = 931/1224 (76%), Gaps = 34/1224 (2%)
Query: 3 AAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTK 62
AAAGA P E+SSDSE E E PQKLIRKVSTSGQIR KT IKEG L K
Sbjct: 17 AAAGAGAAVTSAAASAGPGEDSSDSEAEQE--GPQKLIRKVSTSGQIRTKTSIKEGQLLK 74
Query: 63 QNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCR 122
Q +SFQR K+RYFKLRGRTLYYAK +KS+IFDEVDL+DASVAE+STKN NNSFT+ITP R
Sbjct: 75 QTSSFQRWKKRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAEASTKNANNSFTIITPFR 134
Query: 123 KLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCRE 182
+L+LCA+NRKEMEDWI++LK+VQ RE +E Q++++HFSGMHNWYACSHARPT+CNVCRE
Sbjct: 135 RLMLCAENRKEMEDWISSLKSVQTREPYEVAQFNVEHFSGMHNWYACSHARPTFCNVCRE 194
Query: 183 ALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGN 242
+LSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIED DG+AMPHQWLEGN
Sbjct: 195 SLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDEDGVAMPHQWLEGN 254
Query: 243 LPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALN 302
LPVSAKC VCDKTCGSVLRLQDW+CLWCK MVHT+CK+ CPLG CKVS+IPP ALN
Sbjct: 255 LPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPLGQCKVSIIPPIALN 314
Query: 303 SIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLG 362
S DSDGF +A+ C SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLG
Sbjct: 315 STDSDGFCRATF-SFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLG 373
Query: 363 LRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSAC 422
LRLFQKFD FRILVCGGDGSVGWVLSEID LNL+KQCQLGVLPLGTGNDLARVLGWG +
Sbjct: 374 LRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQLGVLPLGTGNDLARVLGWGGSY 433
Query: 423 DDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYED 482
DDDTQLPQILEKLERASTKMLDRWS+M YE KLP +AS + E SE + YED
Sbjct: 434 DDDTQLPQILEKLERASTKMLDRWSIMTYELKLPPKAS---LLPGPPEASEEFYMTIYED 490
Query: 483 SVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVL 542
SVA HL+KIL SD+H+VVISSAK LCETVKDFVA+V K Y+KT E++ ++ +A KCSVL
Sbjct: 491 SVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVL 550
Query: 543 KEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASAC-PARPQ 601
EKL+ LL+ L +SQA+ LP P I EE S G + ++L P+ +
Sbjct: 551 NEKLEQLLQALHTDSQAAPVLPGLSPLIVEEDAVESSSEESLGESKEQLGDDVTKPSSQK 610
Query: 602 IFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCP 661
+PRE +MLRANSLKKA+RQ+IE K +D+ E ++S +
Sbjct: 611 AVKPRE-IMLRANSLKKAVRQVIEEAGKVMDDPTVHPCEP------ANQSSDYDSTETDE 663
Query: 662 PLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILY 721
++ G + + + +SP + S G S S P S++ LP LNT+I+
Sbjct: 664 SKEEAKDDGAKESITVKTAPRSP-DARASYGH-SQTDSVPGPAVAASKENLPVLNTRIIC 721
Query: 722 PNVRAGMSGSLPGGSVISRLLI-NADPFNSEP------ETLEYYTEKCVMNNYFGIGLDA 774
P +RAG++ S+ G S+I+++L+ N DPF + P ++++ Y+EKCVMNNYFGIGLDA
Sbjct: 722 PGLRAGLAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYSEKCVMNNYFGIGLDA 781
Query: 775 KISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPS 834
KISL+FNNKR+EHPEKCRSRTKN+MWYGVLGT+ELL R+YKNLEQ+V LECDG+ IPLPS
Sbjct: 782 KISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDGQYIPLPS 841
Query: 835 LQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHH 894
LQGIAVLNIPSYAGGTNFWGGTKEDD FAAPSFDDKILEVVA+F SMQMAVSRVI+LQHH
Sbjct: 842 LQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAIFDSMQMAVSRVIKLQHH 901
Query: 895 RIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWED 954
RIAQCRTVKI+I GDEGVPVQVDGEAWVQPPG I+IVHKNRAQ LTRDRAFESTLKSWED
Sbjct: 902 RIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWED 961
Query: 955 KQKCELPRPPSCS----LHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELA 1010
KQKC+ +P + H L+ EE +QM QAA LI I + A H +EQELA
Sbjct: 962 KQKCDSGKPVLRTHLYIHHAIDLATEEVSQMQLCSQAAEELITRICDAATIHCLLEQELA 1021
Query: 1011 HAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKE 1070
HAVNA S ++++ PR E L E+ N +AL +ETE LL G++ LQL+ P +E
Sbjct: 1022 HAVNACSHALNK--ANPRCPESLTRDTATEIAINVKALYNETESLLVGRVPLQLESPHEE 1079
Query: 1071 QLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDLAKR-SRSGKFRLVTKFKKEKNN 1129
++ +AL ++ +L++L + PWL P ++E +D KR +RS FR+V KFKKEK
Sbjct: 1080 RVSNALHSVEVELQKLTEIPWLYYILHPNEDEEPPMDCTKRNNRSTVFRIVPKFKKEKVQ 1139
Query: 1130 KNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGV 1189
K K + PV WGTEEVAAWL+ L+L EYKDIF RHDIRG+ELLHLERRDLKDLG+
Sbjct: 1140 KQKTS----SQPVQKWGTEEVAAWLDLLNLGEYKDIFIRHDIRGAELLHLERRDLKDLGI 1195
Query: 1190 TKVGHMKRILCGIKELSRSAPAVE 1213
KVGH+KRIL GIKEL RS P E
Sbjct: 1196 PKVGHVKRILQGIKELGRSTPQSE 1219
>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
Length = 1164
Score = 1410 bits (3651), Expect = 0.0
Identities = 737/1143 (64%), Positives = 868/1143 (75%), Gaps = 30/1143 (2%)
Query: 3 AAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTK 62
AAAGA P E+SSDSE E E PQKLIRKVSTSGQIR KT IKEG L K
Sbjct: 17 AAAGAGAAVTSAAASAGPGEDSSDSEAEQE--GPQKLIRKVSTSGQIRTKTSIKEGQLLK 74
Query: 63 QNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCR 122
Q +SFQR K+RYFKLRGRTLYYAK +KS+IFDEVDL+DASVAE+STKN NNSFT+ITP R
Sbjct: 75 QTSSFQRWKKRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAEASTKNANNSFTIITPFR 134
Query: 123 KLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCRE 182
+L+LCA+NRKEMEDWI++LK+VQ RE +E Q++++HFSGMHNWYACSHARPT+CNVCRE
Sbjct: 135 RLMLCAENRKEMEDWISSLKSVQTREPYEVAQFNVEHFSGMHNWYACSHARPTFCNVCRE 194
Query: 183 ALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGN 242
+LSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIED DG+AMPHQWLEGN
Sbjct: 195 SLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDEDGVAMPHQWLEGN 254
Query: 243 LPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALN 302
LPVSAKC VCDKTCGSVLRLQDW+CLWCK MVHT+CK+ CPLG CKVS+IPP ALN
Sbjct: 255 LPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPLGQCKVSIIPPIALN 314
Query: 303 SIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLG 362
S DSDGF +A+ C SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLG
Sbjct: 315 STDSDGFCRATFS-FCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLG 373
Query: 363 LRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSAC 422
LRLFQKFD FRILVCGGDGSVGWVLSEID LNL+KQCQLGVLPLGTGNDLARVLGWG +
Sbjct: 374 LRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQLGVLPLGTGNDLARVLGWGGSY 433
Query: 423 DDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYED 482
DDDTQLPQILEKLERASTKMLDRWS+M YE KLP +AS + E SE + YED
Sbjct: 434 DDDTQLPQILEKLERASTKMLDRWSIMTYELKLPPKAS---LLPGPPEASEEFYMTIYED 490
Query: 483 SVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVL 542
SVA HL+KIL SD+H+VVISSAK LCETVKDFVA+V K Y+KT E++ ++ +A KCSVL
Sbjct: 491 SVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVL 550
Query: 543 KEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASAC-PARPQ 601
EKL+ LL+ L +SQA+ LP P I EE S G + ++L P+ +
Sbjct: 551 NEKLEQLLQALHTDSQAAPVLPGLSPLIVEEDAVESSSEESLGESKEQLGDDVTKPSSQK 610
Query: 602 IFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCP 661
+PRE +MLRANSLKKA+RQ+IE K +D+ E ++S +
Sbjct: 611 AVKPRE-IMLRANSLKKAVRQVIEEAGKVMDDPTVHPCEPA------NQSSDYDSTETDE 663
Query: 662 PLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILY 721
++ G + + + +SP + S G S S P S++ LP LNT+I+
Sbjct: 664 SKEEAKDDGAKESITVKTAPRSP-DARASYGH-SQTDSVPGPAVAASKENLPVLNTRIIC 721
Query: 722 PNVRAGMSGSLPGGSVISRLLI-NADPFNSEP------ETLEYYTEKCVMNNYFGIGLDA 774
P +RAG++ S+ G S+I+++L+ N DPF + P ++++ Y+EKCVMNNYFGIGLDA
Sbjct: 722 PGLRAGLAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYSEKCVMNNYFGIGLDA 781
Query: 775 KISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPS 834
KISL+FNNKR+EHPEKCRSRTKN+MWYGVLGT+ELL R+YKNLEQ+V LECDG+ IPLPS
Sbjct: 782 KISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDGQYIPLPS 841
Query: 835 LQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHH 894
LQGIAVLNIPSYAGGTNFWGGTKEDD FAAPSFDDKILEVVA+F SMQMAVSRVI+LQHH
Sbjct: 842 LQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAIFDSMQMAVSRVIKLQHH 901
Query: 895 RIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWED 954
RIAQCRTVKI+I GDEGVPVQVDGEAWVQPPG I+IVHKNRAQ LTRDRAFESTLKSWED
Sbjct: 902 RIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWED 961
Query: 955 KQKCELPRPPSCSL----HPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELA 1010
KQKC+ +P + H L+ EE +QM QAA LI I + A H +EQELA
Sbjct: 962 KQKCDSGKPVLRTHLYIHHAIDLATEEVSQMQLCSQAAEELITRICDAATIHCLLEQELA 1021
Query: 1011 HAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKE 1070
HAVNA S ++++ PR E L E+ N +AL +ETE LL G++ LQL+ P +E
Sbjct: 1022 HAVNACSHALNKA--NPRCPESLTRDTATEIAINVKALYNETESLLVGRVPLQLESPHEE 1079
Query: 1071 QLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDLAKR-SRSGKFRLVTKFKKEKNN 1129
++ +AL ++ +L++L + PWL P ++E +D KR +RS FR+V KFKKEK
Sbjct: 1080 RVSNALHSVEVELQKLTEIPWLYYILHPNEDEEPPMDCTKRNNRSTVFRIVPKFKKEKVQ 1139
Query: 1130 KNK 1132
K K
Sbjct: 1140 KQK 1142
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 770 bits (1989), Expect = 0.0
Identities = 473/1187 (39%), Positives = 662/1187 (55%), Gaps = 134/1187 (11%)
Query: 9 PPGPPQPPPPPPPEESSDSEPEAEPG---SPQKLI---------RKVSTSGQ-------- 48
P P+P P P E + + PEA P SP + R + TS
Sbjct: 147 PELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPR 206
Query: 49 -----IRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASV 103
R K I+KEG + K NSF+R K RYF ++G+ LY+A F+ +DL+ A+V
Sbjct: 207 TPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATV 266
Query: 104 AESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFE-PTQYSMDHFSG 162
AESS +N+ +SF VITP RK+ L A NRK+ME+WI +KT+Q E ++ P + G
Sbjct: 267 AESSCRNLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVG 326
Query: 163 MHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIG 222
MH WY+ R +CNVCRE++ ++ + CEVCK K+H+ CA+RA+ +CKW TL SI
Sbjct: 327 MHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTL-SIT 385
Query: 223 KDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESL 282
D++ AD + MPHQW+EGN+PVS++C VC ++CGS RLQD+RCLWC + VH C+
Sbjct: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
Query: 283 LTKCPLGLCKVSVIPPTALNSIDSDG-------FWKASCPPSCTSPLLVFVNSKSGDNQG 335
+C + SVIPPTAL+ DG FW +C+ PLL+F+NSKSGD+QG
Sbjct: 446 SKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQG 505
Query: 336 VKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNL 395
+ FLR+FKQ LNP+QVFDL+ GGP GL +F+ F FRILVCGGDGSV WVLS ID+ L
Sbjct: 506 IVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGL 565
Query: 396 HKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKL 455
H++CQL V+PLGTGNDLARVLGWG+ + IL ++E+AS ++LDRWSVM E
Sbjct: 566 HEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRET-- 623
Query: 456 PRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFV 515
PRQ + + + +S A L+KIL + + +I + + LC V+DFV
Sbjct: 624 PRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFV 683
Query: 516 ARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAE 575
+ KA+ + +++ + K ++ ++L L+ L +E+ A+S+ + A E
Sbjct: 684 VDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDVLAEEAAATSAEKS-----ATEYA 738
Query: 576 DGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQN 635
D S DR P I + + +L +A SL+K+++ II E+A+DE++
Sbjct: 739 D--------SSKADR--KPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEES 788
Query: 636 AQTQEQEGF--VLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGS 693
QT + F L + E ++ P+ RS+R G+
Sbjct: 789 RQTISVKNFSSTFFLEDDPEDINQT------------SPRRRSRR-------------GT 823
Query: 694 LSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPE 753
LS SS + L LN D + PE
Sbjct: 824 LSSISSL-------KSEDLDNLN----------------------------LDHLHFTPE 848
Query: 754 TLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRT 813
++ + EKCVMNNYFGIGLDAKISLDFN +RDEHP + SR KN MWYG+LGTKELL R+
Sbjct: 849 SIR-FKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRS 907
Query: 814 YKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILE 873
Y+ LE++V LECDG I LP+LQGI VLNI SYAGG NFWG + AP+ DD LE
Sbjct: 908 YRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLE 967
Query: 874 VVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHK 933
VVA+FGS+QMA+SR+I L HHRIAQC V I+I G+EG+PVQVDGEAW+Q PG I+I +K
Sbjct: 968 VVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYK 1027
Query: 934 NRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSL----HPEMLSEEEATQMDQFGQAAG 989
N AQ LTRDR FE+++K WE K E+ P L E LS+EE QM + A
Sbjct: 1028 NAAQMLTRDRDFENSMKMWEYKH-TEIQAAPQPQLDFQDSQESLSDEEYAQMQHLARLAE 1086
Query: 990 VLIHSIREIAQSHRDMEQELAHAVNASSKSM-DRVYGKPR----------TTEGLNCSFV 1038
LI + ++++ H+ + L +VNAS+ + D YG+ E L+ +
Sbjct: 1087 NLISKLNDLSKIHQHV-SVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDA 1145
Query: 1039 LEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEP 1098
+++ + + L +T L K+ + + L SAL M+++ ++L++ W+ P
Sbjct: 1146 VDVTFSLKGLYDDTTAFLDEKLLRSAE--DETALQSALDAMNKEFKKLSEIDWMNPIFVP 1203
Query: 1099 GDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLW 1145
+E+S D KF + K K E+ K K S +LW
Sbjct: 1204 -EEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLW 1249
Score = 35.4 bits (80), Expect = 0.33
Identities = 14/26 (53%), Positives = 15/26 (57%)
Query: 8 PPPGPPQPPPPPPPEESSDSEPEAEP 33
PPP PP PPP PP + EP EP
Sbjct: 32 PPPPPPAPPPAPPLLSEASPEPIPEP 57
Score = 34.3 bits (77), Expect = 0.74
Identities = 16/35 (45%), Positives = 19/35 (54%), Gaps = 6/35 (17%)
Query: 5 AGAPPPGPPQPPPPPPPEES------SDSEPEAEP 33
A +P P PP PPPPPPP S++ PE P
Sbjct: 21 AESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIP 55
Score = 31.6 bits (70), Expect = 4.8
Identities = 20/48 (41%), Positives = 20/48 (41%), Gaps = 16/48 (33%)
Query: 2 AAAAGA---------------PPPGPPQPPPP-PPPEESSDSEPEAEP 33
AAA G PPP PP PPPP PPP SE EP
Sbjct: 6 AAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEP 53
Score = 31.2 bits (69), Expect = 6.3
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 10/48 (20%)
Query: 2 AAAAGAPP---------PGPPQP-PPPPPPEESSDSEPEAEPGSPQKL 39
AA APP P PP P PPPPPP + P SP+ +
Sbjct: 7 AAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPI 54
>gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens]
Length = 773
Score = 210 bits (534), Expect = 8e-54
Identities = 120/330 (36%), Positives = 154/330 (46%), Gaps = 55/330 (16%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W +P YCN+C L GV GL C CK+ H+RC RA +C T + S
Sbjct: 243 GQHVWRLKHFNKPAYCNLCLNMLIGVGKQGLCCSFCKYTVHERCVARAPPSCIKTYVKSK 302
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
+ M H W+EGN P KC C KT L C+WC+ +H C
Sbjct: 303 RNTDV-------MHHYWVEGNCPT--KCDKCHKTVKCYQGLTGLHCVWCQITLHNKCASH 353
Query: 282 LLTKCPLGLCKVSVIPPTAL---------------------------------------- 301
L +C G K ++PPT +
Sbjct: 354 LKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKEKSGSQQPNKVIDKN 413
Query: 302 -----NSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMN 356
NS+ DG P T PLLVFVN KSG QG + R+F+ LLNP QV+ L
Sbjct: 414 KMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKFQYLLNPRQVYSLSG 473
Query: 357 GGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVL 416
GP GL F+ FR+L CGGDG+VGWVL I+ N+ K + +LPLGTGNDLAR L
Sbjct: 474 NGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEKANVGKHPPVAILPLGTGNDLARCL 533
Query: 417 GWGSACDDDTQLPQILEKLERASTKMLDRW 446
WG + + L +IL+ +E ++ MLDRW
Sbjct: 534 RWGGGYEGE-NLMKILKDIENSTEIMLDRW 562
Score = 127 bits (320), Expect = 5e-29
Identities = 74/188 (39%), Positives = 104/188 (55%), Gaps = 27/188 (14%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
++NNYF IG+DA I+ F+ R++HPEK SR KN WY GT E T K L + V
Sbjct: 582 IINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCKKLHESVE 641
Query: 823 LECDGRPIPL--PSLQGIAVLNIPSYAGGTNFWGGTK----------------------E 858
+ECDG I L SL+GIA+LNIPS GG+N WG +K +
Sbjct: 642 IECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSDKRTTVTDAK 701
Query: 859 DDTFAAPSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQVD 917
+ FA+ D++LEVV + G+M+M + ++ R+AQC V I + +P+Q+D
Sbjct: 702 ELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRT--SKSLPMQID 759
Query: 918 GEAWVQPP 925
GE W+Q P
Sbjct: 760 GEPWMQTP 767
>gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens]
Length = 804
Score = 210 bits (534), Expect = 8e-54
Identities = 120/330 (36%), Positives = 154/330 (46%), Gaps = 55/330 (16%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W +P YCN+C L GV GL C CK+ H+RC RA +C T + S
Sbjct: 243 GQHVWRLKHFNKPAYCNLCLNMLIGVGKQGLCCSFCKYTVHERCVARAPPSCIKTYVKSK 302
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
+ M H W+EGN P KC C KT L C+WC+ +H C
Sbjct: 303 RNTDV-------MHHYWVEGNCPT--KCDKCHKTVKCYQGLTGLHCVWCQITLHNKCASH 353
Query: 282 LLTKCPLGLCKVSVIPPTAL---------------------------------------- 301
L +C G K ++PPT +
Sbjct: 354 LKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKEKSGSQQPNKVIDKN 413
Query: 302 -----NSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMN 356
NS+ DG P T PLLVFVN KSG QG + R+F+ LLNP QV+ L
Sbjct: 414 KMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKFQYLLNPRQVYSLSG 473
Query: 357 GGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVL 416
GP GL F+ FR+L CGGDG+VGWVL I+ N+ K + +LPLGTGNDLAR L
Sbjct: 474 NGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEKANVGKHPPVAILPLGTGNDLARCL 533
Query: 417 GWGSACDDDTQLPQILEKLERASTKMLDRW 446
WG + + L +IL+ +E ++ MLDRW
Sbjct: 534 RWGGGYEGE-NLMKILKDIENSTEIMLDRW 562
Score = 139 bits (351), Expect = 1e-32
Identities = 81/202 (40%), Positives = 113/202 (55%), Gaps = 27/202 (13%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
++NNYF IG+DA I+ F+ R++HPEK SR KN WY GT E T K L + V
Sbjct: 582 IINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCKKLHESVE 641
Query: 823 LECDGRPIPL--PSLQGIAVLNIPSYAGGTNFWGGTK----------------------E 858
+ECDG I L SL+GIA+LNIPS GG+N WG +K +
Sbjct: 642 IECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSDKRTTVTDAK 701
Query: 859 DDTFAAPSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQVD 917
+ FA+ D++LEVV + G+M+M + ++ R+AQC V I + +P+Q+D
Sbjct: 702 ELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRT--SKSLPMQID 759
Query: 918 GEAWVQPPGYIRIVHKNRAQTL 939
GE W+Q P I+I HKN+A L
Sbjct: 760 GEPWMQTPCTIKITHKNQAPML 781
>gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens]
Length = 791
Score = 207 bits (528), Expect = 4e-53
Identities = 122/301 (40%), Positives = 152/301 (50%), Gaps = 28/301 (9%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W +PTYCN C L GV GL C CK+ H+RC R C T +
Sbjct: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGCVKTYSKA- 328
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
G M H W+EGN S KC C K+ + C+WC+ H C+
Sbjct: 329 ------KRSGEVMQHAWVEGNS--SVKCDRCHKSIKCYQSVTARHCVWCRMTFHRKCE-- 378
Query: 282 LLTKCPLGLCKVSVIPPTALNSID-------SDGFWKAS---------CPPSCTSPLLVF 325
L T C G + ++ PT++ I SDG A P T PLLV
Sbjct: 379 LSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVL 438
Query: 326 VNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGW 385
VN KSG QG + LR+F LLNP QVF+L NGGP GL F+ FR+L CGGDG+VGW
Sbjct: 439 VNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGW 498
Query: 386 VLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDR 445
+L ID N K + VLPLGTGNDLAR L WG + + L +IL+ +E++ MLDR
Sbjct: 499 ILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGS-LTKILKDIEQSPLVMLDR 557
Query: 446 W 446
W
Sbjct: 558 W 558
Score = 140 bits (354), Expect = 6e-33
Identities = 80/193 (41%), Positives = 112/193 (58%), Gaps = 21/193 (10%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
+MNNYF IG+DA I+ F+ R++HPEK SR KN +WY GT E T K L +
Sbjct: 578 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 637
Query: 823 LECDGRPIPLPS--LQGIAVLNIPSYAGGTNFWGGTKEDDT----------------FAA 864
LECDG + L + L+GIA+LNIPS GGTN WG K++ F
Sbjct: 638 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 697
Query: 865 PSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQ 923
D++LEVV + G+M+M + ++ R+AQC +V +I ++ +P+QVDGE W+Q
Sbjct: 698 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASV--TIRTNKLLPMQVDGEPWMQ 755
Query: 924 PPGYIRIVHKNRA 936
P I+I HKN+A
Sbjct: 756 PCCTIKITHKNQA 768
>gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 206 bits (523), Expect = 1e-52
Identities = 119/309 (38%), Positives = 165/309 (53%), Gaps = 32/309 (10%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W RP YCN+C ++ G+ GLSC +CK+ H +CA++A C+ +T A
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
KDI G+ H W+ G S +C C K L C+WC +H C ++
Sbjct: 262 RKDI-----GV-QSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQA 314
Query: 282 LLTKCPLGLCKVSVIPPTALN-SIDSDGFWKASC---------------------PPSCT 319
+ +C GL + ++PP+++ S+ + G + + P T
Sbjct: 315 VGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNT 374
Query: 320 SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGG 379
PLLVFVN KSG QG + L +F+ +LNP QVF+L+ GP +GLRLF+ RILVCGG
Sbjct: 375 HPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGG 434
Query: 380 DGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAS 439
DG+VGW+L ID NL + VLPLGTGNDLAR L WG + L +IL+ LE +
Sbjct: 435 DGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQ-NLAKILKDLEMSK 493
Query: 440 TKMLDRWSV 448
+DRWSV
Sbjct: 494 VVHMDRWSV 502
Score = 126 bits (317), Expect = 1e-28
Identities = 75/203 (36%), Positives = 112/203 (55%), Gaps = 28/203 (13%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
++NNYF IG+DA I+ F+ R+++PEK SR KN +WY T E + T K LE+ +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 823 LECDGRPIPLP--SLQGIAVLNIPSYAGGTNFWGGTK--EDDTF---------------- 862
+E G+P+ L SL+GIAVLNIPS GG+N WG T+ D +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 863 -----AAPSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQV 916
P DK LEVV + G+++M + ++ R+A+C +I+ + +P+Q+
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCS--EITFHTTKTLPMQI 697
Query: 917 DGEAWVQPPGYIRIVHKNRAQTL 939
DGE W+Q P I+I HKN+ L
Sbjct: 698 DGEPWMQTPCTIKITHKNQMPML 720
>gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 206 bits (523), Expect = 1e-52
Identities = 119/309 (38%), Positives = 165/309 (53%), Gaps = 32/309 (10%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W RP YCN+C ++ G+ GLSC +CK+ H +CA++A C+ +T A
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
KDI G+ H W+ G S +C C K L C+WC +H C ++
Sbjct: 262 RKDI-----GV-QSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQA 314
Query: 282 LLTKCPLGLCKVSVIPPTALN-SIDSDGFWKASC---------------------PPSCT 319
+ +C GL + ++PP+++ S+ + G + + P T
Sbjct: 315 VGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNT 374
Query: 320 SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGG 379
PLLVFVN KSG QG + L +F+ +LNP QVF+L+ GP +GLRLF+ RILVCGG
Sbjct: 375 HPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGG 434
Query: 380 DGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAS 439
DG+VGW+L ID NL + VLPLGTGNDLAR L WG + L +IL+ LE +
Sbjct: 435 DGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQ-NLAKILKDLEMSK 493
Query: 440 TKMLDRWSV 448
+DRWSV
Sbjct: 494 VVHMDRWSV 502
Score = 126 bits (317), Expect = 1e-28
Identities = 75/203 (36%), Positives = 112/203 (55%), Gaps = 28/203 (13%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
++NNYF IG+DA I+ F+ R+++PEK SR KN +WY T E + T K LE+ +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 823 LECDGRPIPLP--SLQGIAVLNIPSYAGGTNFWGGTK--EDDTF---------------- 862
+E G+P+ L SL+GIAVLNIPS GG+N WG T+ D +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 863 -----AAPSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQV 916
P DK LEVV + G+++M + ++ R+A+C +I+ + +P+Q+
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCS--EITFHTTKTLPMQI 697
Query: 917 DGEAWVQPPGYIRIVHKNRAQTL 939
DGE W+Q P I+I HKN+ L
Sbjct: 698 DGEPWMQTPCTIKITHKNQMPML 720
>gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 206 bits (523), Expect = 1e-52
Identities = 119/309 (38%), Positives = 165/309 (53%), Gaps = 32/309 (10%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W RP YCN+C ++ G+ GLSC +CK+ H +CA++A C+ +T A
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
KDI G+ H W+ G S +C C K L C+WC +H C ++
Sbjct: 262 RKDI-----GV-QSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQA 314
Query: 282 LLTKCPLGLCKVSVIPPTALN-SIDSDGFWKASC---------------------PPSCT 319
+ +C GL + ++PP+++ S+ + G + + P T
Sbjct: 315 VGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNT 374
Query: 320 SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGG 379
PLLVFVN KSG QG + L +F+ +LNP QVF+L+ GP +GLRLF+ RILVCGG
Sbjct: 375 HPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGG 434
Query: 380 DGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAS 439
DG+VGW+L ID NL + VLPLGTGNDLAR L WG + L +IL+ LE +
Sbjct: 435 DGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQ-NLAKILKDLEMSK 493
Query: 440 TKMLDRWSV 448
+DRWSV
Sbjct: 494 VVHMDRWSV 502
Score = 126 bits (317), Expect = 1e-28
Identities = 75/203 (36%), Positives = 112/203 (55%), Gaps = 28/203 (13%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
++NNYF IG+DA I+ F+ R+++PEK SR KN +WY T E + T K LE+ +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 823 LECDGRPIPLP--SLQGIAVLNIPSYAGGTNFWGGTK--EDDTF---------------- 862
+E G+P+ L SL+GIAVLNIPS GG+N WG T+ D +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 863 -----AAPSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQV 916
P DK LEVV + G+++M + ++ R+A+C +I+ + +P+Q+
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCS--EITFHTTKTLPMQI 697
Query: 917 DGEAWVQPPGYIRIVHKNRAQTL 939
DGE W+Q P I+I HKN+ L
Sbjct: 698 DGEPWMQTPCTIKITHKNQMPML 720
>gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 206 bits (523), Expect = 1e-52
Identities = 119/309 (38%), Positives = 165/309 (53%), Gaps = 32/309 (10%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W RP YCN+C ++ G+ GLSC +CK+ H +CA++A C+ +T A
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
KDI G+ H W+ G S +C C K L C+WC +H C ++
Sbjct: 262 RKDI-----GV-QSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQA 314
Query: 282 LLTKCPLGLCKVSVIPPTALN-SIDSDGFWKASC---------------------PPSCT 319
+ +C GL + ++PP+++ S+ + G + + P T
Sbjct: 315 VGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNT 374
Query: 320 SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGG 379
PLLVFVN KSG QG + L +F+ +LNP QVF+L+ GP +GLRLF+ RILVCGG
Sbjct: 375 HPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGG 434
Query: 380 DGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAS 439
DG+VGW+L ID NL + VLPLGTGNDLAR L WG + L +IL+ LE +
Sbjct: 435 DGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQ-NLAKILKDLEMSK 493
Query: 440 TKMLDRWSV 448
+DRWSV
Sbjct: 494 VVHMDRWSV 502
Score = 126 bits (317), Expect = 1e-28
Identities = 75/203 (36%), Positives = 112/203 (55%), Gaps = 28/203 (13%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
++NNYF IG+DA I+ F+ R+++PEK SR KN +WY T E + T K LE+ +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 823 LECDGRPIPLP--SLQGIAVLNIPSYAGGTNFWGGTK--EDDTF---------------- 862
+E G+P+ L SL+GIAVLNIPS GG+N WG T+ D +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 863 -----AAPSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQV 916
P DK LEVV + G+++M + ++ R+A+C +I+ + +P+Q+
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCS--EITFHTTKTLPMQI 697
Query: 917 DGEAWVQPPGYIRIVHKNRAQTL 939
DGE W+Q P I+I HKN+ L
Sbjct: 698 DGEPWMQTPCTIKITHKNQMPML 720
>gi|4503313 diacylglycerol kinase epsilon [Homo sapiens]
Length = 567
Score = 189 bits (481), Expect = 1e-47
Identities = 132/396 (33%), Positives = 191/396 (48%), Gaps = 41/396 (10%)
Query: 164 HNWYACS-HARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNN--CKWTTLAS 220
H W ++PTYC VC + + G C+ C + + C +A CK L +
Sbjct: 60 HGWRDTDLFSQPTYCCVCAQHIL----QGAFCDCCGLRVDEGCLRKADKRFQCKEIMLKN 115
Query: 221 IGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKE 280
K + AMPH W+ GN+P+ + C VC + CG +L D+RC+WC+ VH C +
Sbjct: 116 DTKVLD------AMPHHWIRGNVPLCSYCMVCKQQCGCQPKLCDYRCIWCQKTVHDECMK 169
Query: 281 SLL--TKCPLGLCKVSVIPPTALNSID-------SDGFWKASCPPSCTSPLLVFVNSKSG 331
+ L KC G K +IPP+ L SI+ +D AS +PL++ NS+SG
Sbjct: 170 NSLKNEKCDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASKLGKQWTPLIILANSRSG 229
Query: 332 DNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRL--FQKFDTFRILVCGGDGSVGWVLSE 389
N G L F+ LLNP QVFD+ P L+L + + R+LVCGGDG+VGWVL
Sbjct: 230 TNMGEGLLGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCGGDGTVGWVLDA 289
Query: 390 IDSLNLHKQ----CQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDR 445
+D + + Q Q+ VLPLGTGNDL+ LGWG+ + + Q+L + A LDR
Sbjct: 290 VDDMKIKGQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDR 349
Query: 446 WSVMA-----YEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVV 500
W V Y + P++ T+ FS + L + AH K S S +
Sbjct: 350 WKVQVTNKGYYNLRKPKE---FTMNNYFSVGPDALMALNFH----AHREK-APSLFSSRI 401
Query: 501 ISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMA 536
++ A L KD + + K K E + E +A
Sbjct: 402 LNKAVYLFYGTKDCLVQECKDLNKKVELELDGERVA 437
Score = 133 bits (335), Expect = 9e-31
Identities = 84/221 (38%), Positives = 117/221 (52%), Gaps = 10/221 (4%)
Query: 727 GMSGSLPGGSVISRLL----INADPFNSEPETLEYYT----EKCVMNNYFGIGLDAKISL 778
G +G +P V+ ++ I D + + YY ++ MNNYF +G DA ++L
Sbjct: 325 GYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFTMNNYFSVGPDALMAL 384
Query: 779 DFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGI 838
+F+ R++ P SR N Y GTK+ L + K+L +KV LE DG + LPSL+GI
Sbjct: 385 NFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKVELELDGERVALPSLEGI 444
Query: 839 AVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQ 898
VLNI + GG W G D+T+ DD +LEVV V+GS A +V RI Q
Sbjct: 445 IVLNIGYWGGGCRLWEG-MGDETYPLARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQ 503
Query: 899 CRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTL 939
TV++ IL +P+QVDGE W Q P + I HK A L
Sbjct: 504 AHTVRL-ILKCSMMPMQVDGEPWAQGPCTVTITHKTHAMML 543
>gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens]
Length = 766
Score = 164 bits (414), Expect = 6e-40
Identities = 106/301 (35%), Positives = 134/301 (44%), Gaps = 53/301 (17%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W +PTYCN C L GV GL C CK+ H+RC R C T +
Sbjct: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGCVKTYSKA- 328
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
G M H W+EGN S KC C K+ + C+WC+ H C+
Sbjct: 329 ------KRSGEVMQHAWVEGNS--SVKCDRCHKSIKCYQSVTARHCVWCRMTFHRKCE-- 378
Query: 282 LLTKCPLGLCKVSVIPPTALNSID-------SDGFWKAS---------CPPSCTSPLLVF 325
L T C G + ++ PT++ I SDG A P T PLLV
Sbjct: 379 LSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVL 438
Query: 326 VNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGW 385
VN KSG QG + L F+ FR+L CGGDG+VGW
Sbjct: 439 VNPKSGGRQGER-------------------------LNFFRDTPDFRVLACGGDGTVGW 473
Query: 386 VLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDR 445
+L ID N K + VLPLGTGNDLAR L WG + + L +IL+ +E++ MLDR
Sbjct: 474 ILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGS-LTKILKDIEQSPLVMLDR 532
Query: 446 W 446
W
Sbjct: 533 W 533
Score = 140 bits (354), Expect = 6e-33
Identities = 80/193 (41%), Positives = 112/193 (58%), Gaps = 21/193 (10%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
+MNNYF IG+DA I+ F+ R++HPEK SR KN +WY GT E T K L +
Sbjct: 553 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 612
Query: 823 LECDGRPIPLPS--LQGIAVLNIPSYAGGTNFWGGTKEDDT----------------FAA 864
LECDG + L + L+GIA+LNIPS GGTN WG K++ F
Sbjct: 613 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 672
Query: 865 PSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQ 923
D++LEVV + G+M+M + ++ R+AQC +V +I ++ +P+QVDGE W+Q
Sbjct: 673 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASV--TIRTNKLLPMQVDGEPWMQ 730
Query: 924 PPGYIRIVHKNRA 936
P I+I HKN+A
Sbjct: 731 PCCTIKITHKNQA 743
>gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens]
Length = 752
Score = 154 bits (388), Expect = 6e-37
Identities = 108/301 (35%), Positives = 137/301 (45%), Gaps = 67/301 (22%)
Query: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
G H W +PTYCN C L GV GL C CK+T
Sbjct: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTY----------------CKYT----- 308
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
+ + + N+P C KT R ++ H C+
Sbjct: 309 ------------VHERCVSRNIPG------CVKTYSKAKRSGEF---------HRKCE-- 339
Query: 282 LLTKCPLGLCKVSVIPPTALNSID-------SDGFWKAS---------CPPSCTSPLLVF 325
L T C G + ++ PT++ I SDG A P T PLLV
Sbjct: 340 LSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVL 399
Query: 326 VNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGW 385
VN KSG QG + LR+F LLNP QVF+L NGGP GL F+ FR+L CGGDG+VGW
Sbjct: 400 VNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGW 459
Query: 386 VLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDR 445
+L ID N K + VLPLGTGNDLAR L WG + + L +IL+ +E++ MLDR
Sbjct: 460 ILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGS-LTKILKDIEQSPLVMLDR 518
Query: 446 W 446
W
Sbjct: 519 W 519
Score = 140 bits (354), Expect = 6e-33
Identities = 80/193 (41%), Positives = 112/193 (58%), Gaps = 21/193 (10%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
+MNNYF IG+DA I+ F+ R++HPEK SR KN +WY GT E T K L +
Sbjct: 539 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 598
Query: 823 LECDGRPIPLPS--LQGIAVLNIPSYAGGTNFWGGTKEDDT----------------FAA 864
LECDG + L + L+GIA+LNIPS GGTN WG K++ F
Sbjct: 599 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 658
Query: 865 PSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQ 923
D++LEVV + G+M+M + ++ R+AQC +V +I ++ +P+QVDGE W+Q
Sbjct: 659 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASV--TIRTNKLLPMQVDGEPWMQ 716
Query: 924 PPGYIRIVHKNRA 936
P I+I HKN+A
Sbjct: 717 PCCTIKITHKNQA 729
>gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]
Length = 929
Score = 151 bits (381), Expect = 4e-36
Identities = 108/337 (32%), Positives = 145/337 (43%), Gaps = 56/337 (16%)
Query: 162 GMHNWYACS------HARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATN---N 212
G H W+ + + YC V R V+ C CK H C +
Sbjct: 96 GEHIWFETNVSGDFCYVGEQYC-VARMLQKSVSRR--KCAACKIVVHTPCIEQLEKINFR 152
Query: 213 CKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWR-----C 267
CK + S +++ E + H W+ KC C K C
Sbjct: 153 CKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISC 208
Query: 268 LWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL-------NSIDS---------- 306
WCK H+ +L + C LG+ VIPPT + N++ +
Sbjct: 209 SWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFK 268
Query: 307 ---------DGFWKA----SCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFD 353
+G W+ P PLLVFVN KSG NQG K ++ F LNP QVFD
Sbjct: 269 RKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFD 328
Query: 354 LMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLA 413
L GGP L +++K RIL CGGDG+VGW+LS +D L L + +LPLGTGNDLA
Sbjct: 329 LSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLA 388
Query: 414 RVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 450
R L WG D+ + +IL +E + LDRW + A
Sbjct: 389 RTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 424
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/278 (27%), Positives = 126/278 (45%), Gaps = 23/278 (8%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 447 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 506
Query: 823 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 877
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 507 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 565
Query: 878 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 937
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 566 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 620
Query: 938 TLTRDRAFESTLKSWEDKQ------KCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVL 991
T+ + S D+Q + ++ R S+H + Q+ + G +
Sbjct: 621 TMVQKAKRRSAAPLHSDQQPVPEQLRIQVSR---VSMHDYEALHYDKEQLKEASVPLGTV 677
Query: 992 I---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 1026
+ S E+ ++H + Q+ A S + ++ K
Sbjct: 678 VVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 715
>gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens]
Length = 895
Score = 151 bits (381), Expect = 4e-36
Identities = 108/337 (32%), Positives = 145/337 (43%), Gaps = 56/337 (16%)
Query: 162 GMHNWYACS------HARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATN---N 212
G H W+ + + YC V R V+ C CK H C +
Sbjct: 62 GEHIWFETNVSGDFCYVGEQYC-VARMLQKSVSRR--KCAACKIVVHTPCIEQLEKINFR 118
Query: 213 CKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWR-----C 267
CK + S +++ E + H W+ KC C K C
Sbjct: 119 CKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISC 174
Query: 268 LWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL-------NSIDS---------- 306
WCK H+ +L + C LG+ VIPPT + N++ +
Sbjct: 175 SWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFK 234
Query: 307 ---------DGFWKA----SCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFD 353
+G W+ P PLLVFVN KSG NQG K ++ F LNP QVFD
Sbjct: 235 RKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFD 294
Query: 354 LMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLA 413
L GGP L +++K RIL CGGDG+VGW+LS +D L L + +LPLGTGNDLA
Sbjct: 295 LSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLA 354
Query: 414 RVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 450
R L WG D+ + +IL +E + LDRW + A
Sbjct: 355 RTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 390
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/278 (27%), Positives = 126/278 (45%), Gaps = 23/278 (8%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 413 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 472
Query: 823 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 877
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 473 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 531
Query: 878 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 937
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 532 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 586
Query: 938 TLTRDRAFESTLKSWEDKQ------KCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVL 991
T+ + S D+Q + ++ R S+H + Q+ + G +
Sbjct: 587 TMVQKAKRRSAAPLHSDQQPVPEQLRIQVSR---VSMHDYEALHYDKEQLKEASVPLGTV 643
Query: 992 I---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 1026
+ S E+ ++H + Q+ A S + ++ K
Sbjct: 644 VVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 681
>gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]
Length = 1117
Score = 150 bits (379), Expect = 7e-36
Identities = 100/299 (33%), Positives = 133/299 (44%), Gaps = 47/299 (15%)
Query: 194 CEVCKFKAHKRCAVRATN---NCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCT 250
C CK H C + CK + S +++ E + H W+ KC
Sbjct: 319 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCR 374
Query: 251 VCDKTCGSVLRLQDWR-----CLWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL 301
C K C WCK H+ +L + C LG+ VIPPT +
Sbjct: 375 HCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI 434
Query: 302 -------NSIDS-------------------DGFWKA----SCPPSCTSPLLVFVNSKSG 331
N++ + +G W+ P PLLVFVN KSG
Sbjct: 435 LRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSG 494
Query: 332 DNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEID 391
NQG K ++ F LNP QVFDL GGP L +++K RIL CGGDG+VGW+LS +D
Sbjct: 495 GNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLD 554
Query: 392 SLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 450
L L + +LPLGTGNDLAR L WG D+ + +IL +E + LDRW + A
Sbjct: 555 QLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 612
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/278 (27%), Positives = 126/278 (45%), Gaps = 23/278 (8%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
Query: 823 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 877
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 695 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 753
Query: 878 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 937
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 754 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 808
Query: 938 TLTRDRAFESTLKSWEDKQ------KCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVL 991
T+ + S D+Q + ++ R S+H + Q+ + G +
Sbjct: 809 TMVQKAKRRSAAPLHSDQQPVPEQLRIQVSR---VSMHDYEALHYDKEQLKEASVPLGTV 865
Query: 992 I---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 1026
+ S E+ ++H + Q+ A S + ++ K
Sbjct: 866 VVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 903
>gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens]
Length = 945
Score = 150 bits (379), Expect = 7e-36
Identities = 100/299 (33%), Positives = 133/299 (44%), Gaps = 47/299 (15%)
Query: 194 CEVCKFKAHKRCAVRATN---NCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCT 250
C CK H C + CK + S +++ E + H W+ KC
Sbjct: 147 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCR 202
Query: 251 VCDKTCGSVLRLQDWR-----CLWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL 301
C K C WCK H+ +L + C LG+ VIPPT +
Sbjct: 203 HCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI 262
Query: 302 -------NSIDS-------------------DGFWKA----SCPPSCTSPLLVFVNSKSG 331
N++ + +G W+ P PLLVFVN KSG
Sbjct: 263 LRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSG 322
Query: 332 DNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEID 391
NQG K ++ F LNP QVFDL GGP L +++K RIL CGGDG+VGW+LS +D
Sbjct: 323 GNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLD 382
Query: 392 SLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 450
L L + +LPLGTGNDLAR L WG D+ + +IL +E + LDRW + A
Sbjct: 383 QLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 440
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/278 (27%), Positives = 126/278 (45%), Gaps = 23/278 (8%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 463 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 522
Query: 823 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 877
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 523 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 581
Query: 878 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 937
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 582 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 636
Query: 938 TLTRDRAFESTLKSWEDKQ------KCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVL 991
T+ + S D+Q + ++ R S+H + Q+ + G +
Sbjct: 637 TMVQKAKRRSAAPLHSDQQPVPEQLRIQVSR---VSMHDYEALHYDKEQLKEASVPLGTV 693
Query: 992 I---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 1026
+ S E+ ++H + Q+ A S + ++ K
Sbjct: 694 VVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 731
>gi|4758156 diacylglycerol kinase, iota [Homo sapiens]
Length = 1065
Score = 142 bits (358), Expect = 2e-33
Identities = 101/299 (33%), Positives = 127/299 (42%), Gaps = 50/299 (16%)
Query: 194 CEVCKFKAHKRCAVRATN---NCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCT 250
C VCK H C + CK T + E+ + H W+ KC
Sbjct: 210 CAVCKIVVHTACIEQLEKINFRCKPTFREGGSRSPRENF----VRHHWVHRRRQ-EGKCK 264
Query: 251 VCDKTCGSVLRLQDWR-----CLWCKAMVHTSCKESLL----TKCPLGLCKVSVIPPTAL 301
C K C WCK H +L C LG ++PPT +
Sbjct: 265 QCGKGFQQKFSFHSKEIVAISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPPTWI 324
Query: 302 -------NSIDSDG-------------------------FWKASCPPSCTSPLLVFVNSK 329
NS+ + F PLLVFVN K
Sbjct: 325 IKVKKPQNSLKASNRKKKRTSFKRKASKRGMEQENKGRPFVIKPISSPLMKPLLVFVNPK 384
Query: 330 SGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSE 389
SG NQG K L+ F LNP QVFDL GP L L++K RIL CGGDG+VGW+LS
Sbjct: 385 SGGNQGTKVLQMFMWYLNPRQVFDLSQEGPKDALELYRKVPNLRILACGGDGTVGWILSI 444
Query: 390 IDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSV 448
+D L L Q +GVLPLGTGNDLAR L WG D+ + +IL ++E + LDRW++
Sbjct: 445 LDELQLSPQPPVGVLPLGTGNDLARTLNWGGGYTDE-PVSKILCQVEDGTVVQLDRWNL 502
Score = 103 bits (257), Expect = 1e-21
Identities = 63/188 (33%), Positives = 98/188 (52%), Gaps = 14/188 (7%)
Query: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L R+ ++L + V
Sbjct: 526 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVK 585
Query: 823 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 877
+ CDG + P +Q I LNIP Y GT WG + F DD +EV+
Sbjct: 586 VVCDGTDL-TPKIQELKFQCIVFLNIPRYCAGTMPWGNPGDHHDFEPQRHDDGYIEVI-- 642
Query: 878 FGSMQMAVSRVIRLQHH--RIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNR 935
MA +++ H R+ QCR ++ +L + +P+QVDGE P IRI +N+
Sbjct: 643 --GFTMASLAALQVGGHGERLHQCR--EVMLLTYKSIPMQVDGEPCRLAPAMIRISLRNQ 698
Query: 936 AQTLTRDR 943
A + + +
Sbjct: 699 ANMVQKSK 706
>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
Length = 942
Score = 132 bits (332), Expect = 2e-30
Identities = 78/180 (43%), Positives = 102/180 (56%), Gaps = 13/180 (7%)
Query: 315 PPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRI 374
P SC PLLVFVN KSG +G L F++LLNP QVFDL NGGP GL LF + FR+
Sbjct: 584 PDSC--PLLVFVNPKSGGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRV 641
Query: 375 LVCGGDGSVGWVLSEIDSLNLHKQC---QLGVLPLGTGNDLARVLGWGSACDDDTQLPQI 431
LVCGGDG+VGWVL ++ C + +LPLGTGNDL RVL WG+ + +
Sbjct: 642 LVCGGDGTVGWVLGALEETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPF-SV 700
Query: 432 LEKLERASTKMLDRWSVM--AYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLS 489
L ++ A ++DRW+++ A+EA S+ T D VQ + + A LS
Sbjct: 701 LLSVDEADAVLMDRWTILLDAHEA-----GSAENDTADAEPPKIVQMSNYCGIGIDAELS 755
Score = 119 bits (297), Expect = 2e-26
Identities = 69/183 (37%), Positives = 109/183 (59%), Gaps = 6/183 (3%)
Query: 749 NSEPETLEYYTEKCV-MNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTK 807
++E +T + K V M+NY GIG+DA++SLDF+ R+E P K SR N Y +G +
Sbjct: 726 SAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVRVGLQ 785
Query: 808 ELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSF 867
++ H ++L +++ L+ + + + LPS++G+ +NIPS+ G + W G+ D F P
Sbjct: 786 KISHS--RSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLW-GSDSDTRFEKPRM 842
Query: 868 DDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGY 927
DD +LEVV V G + M + RIAQ ++++L + PVQVDGE WVQ PG+
Sbjct: 843 DDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLL--KATPVQVDGEPWVQAPGH 900
Query: 928 IRI 930
+ I
Sbjct: 901 MII 903
Score = 87.4 bits (215), Expect = 7e-17
Identities = 49/136 (36%), Positives = 65/136 (47%), Gaps = 11/136 (8%)
Query: 176 YCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMP 235
+C VCR+ L H CEVC+ H C A ++C+ +D +D D
Sbjct: 134 FCAVCRKVLEAPALH---CEVCELHLHPDCVPFACSDCR-----QCHQDGHQDHD--THH 183
Query: 236 HQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSV 295
H W EGNLP A+C VC KTCGS L RC WC H+ C +L +C G + V
Sbjct: 184 HHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLRSLV 243
Query: 296 IPPTALNSIDSDGFWK 311
+PP + + GF K
Sbjct: 244 LPPACVRLLPG-GFSK 258
Score = 44.7 bits (104), Expect = 5e-04
Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 15/123 (12%)
Query: 164 HNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGK 223
H++ + +PT+C++C + + G+ G C+VC F +H++C C S+
Sbjct: 61 HSFRKVTLTKPTFCHLCSDFIWGLA--GFLCDVCNFMSHEKCLKHVRIPC-----TSVAP 113
Query: 224 DIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLL 283
++ + + H + L C VC K VL C C+ +H C
Sbjct: 114 SLVR----VPVAHCFGPRGLHKRKFCAVCRK----VLEAPALHCEVCELHLHPDCVPFAC 165
Query: 284 TKC 286
+ C
Sbjct: 166 SDC 168
Score = 35.4 bits (80), Expect = 0.33
Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 158 DHFSGMHNWYACSHARPTYCNVCREAL-SGVTSHGLSCEVCKFKAHKRCAVRATNNCKWT 216
DH + H+W + C VCR+ S G+ CE C +AH C+ C +
Sbjct: 178 DHDTHHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFG 237
Query: 217 TLASI 221
L S+
Sbjct: 238 RLRSL 242
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 68.2 bits (165), Expect = 5e-11
Identities = 33/65 (50%), Positives = 45/65 (69%)
Query: 1141 PVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILC 1200
PVHLW +VA WLE L+L E+K+ F ++I GS L +L++ DL DLGVT+VGH I
Sbjct: 1782 PVHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIER 1841
Query: 1201 GIKEL 1205
+K+L
Sbjct: 1842 ALKQL 1846
>gi|28557781 protein kinase C, eta [Homo sapiens]
Length = 683
Score = 66.2 bits (160), Expect = 2e-10
Identities = 39/125 (31%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Query: 164 HNWYACSHARPTYCNVCREALSGV-TSHGLSCEVCKFKAHKRCAVRATNNCK-WTTLASI 221
H + A +PTYC+ CRE + GV G C+VC HKRC C + +
Sbjct: 172 HKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKV 231
Query: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
I E GI +PH++ N V C C ++R Q +C CK VH C+ +
Sbjct: 232 DSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMR-QGLQCKICKMNVHIRCQAN 290
Query: 282 LLTKC 286
+ C
Sbjct: 291 VAPNC 295
Score = 45.8 bits (107), Expect = 2e-04
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 156 SMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
++ H +HN+ PT+C+ C L G+ GL C++CK H RC NC
Sbjct: 243 NIPHKFSIHNYKV-----PTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNC 295
>gi|47157325 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 64.3 bits (155), Expect = 7e-10
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 159 HFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTL 218
H+ H + A +PT+C+VC++ + G+ G C C HK+C + C T
Sbjct: 154 HYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAA 213
Query: 219 ASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSV---LRLQDWRCLWCKAMVH 275
S ++ I MPH++ N T CD CGS+ L Q +C C VH
Sbjct: 214 NSRDTIFQKERFNIDMPHRFKVHNY---MSPTFCDH-CGSLLWGLVKQGLKCEDCGMNVH 269
Query: 276 TSCKESLLTKC 286
C+E + C
Sbjct: 270 HKCREKVANLC 280
>gi|31377782 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 64.3 bits (155), Expect = 7e-10
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 159 HFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTL 218
H+ H + A +PT+C+VC++ + G+ G C C HK+C + C T
Sbjct: 154 HYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAA 213
Query: 219 ASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSV---LRLQDWRCLWCKAMVH 275
S ++ I MPH++ N T CD CGS+ L Q +C C VH
Sbjct: 214 NSRDTIFQKERFNIDMPHRFKVHNY---MSPTFCDH-CGSLLWGLVKQGLKCEDCGMNVH 269
Query: 276 TSCKESLLTKC 286
C+E + C
Sbjct: 270 HKCREKVANLC 280
>gi|4885563 protein kinase C, epsilon [Homo sapiens]
Length = 737
Score = 62.8 bits (151), Expect = 2e-09
Identities = 43/148 (29%), Positives = 60/148 (40%), Gaps = 9/148 (6%)
Query: 164 HNWYACSHARPTYCNVCREALSGVT-SHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIG 222
H + A +PTYC+ CR+ + GV G C+VC HKRC C
Sbjct: 170 HKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQETP 229
Query: 223 KDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESL 282
+ + MPH++ N V C C +LR Q +C CK VH C+ ++
Sbjct: 230 DQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLR-QGLQCKVCKMNVHRRCETNV 288
Query: 283 LTKCPL---GLCKV----SVIPPTALNS 303
C + G+ KV V P NS
Sbjct: 289 APNCGVDARGIAKVLADLGVTPDKITNS 316
Score = 51.6 bits (122), Expect = 4e-06
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 139 AALKTVQNREHFEPTQYS--MDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEV 196
A LK + + ++S M H G+HN+ PT+C+ C L G+ GL C+V
Sbjct: 221 AGLKKQETPDQVGSQRFSVNMPHKFGIHNYKV-----PTFCDHCGSLLWGLLRQGLQCKV 275
Query: 197 CKFKAHKRCAVRATNNC 213
CK H+RC NC
Sbjct: 276 CKMNVHRRCETNVAPNC 292
>gi|120659787 protein kinase D2 isoform B [Homo sapiens]
Length = 721
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/50 (46%), Positives = 30/50 (60%)
Query: 164 HNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
H + S+ RPT C C++ L G+ GL C+ CKF HKRCA R N+C
Sbjct: 108 HTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDC 157
Score = 35.0 bits (79), Expect = 0.43
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 184 LSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
L G+ GL C+ C HKRCA NNC
Sbjct: 2 LFGLVRQGLKCDGCGLNYHKRCAFSIPNNC 31
>gi|120659785 protein kinase D2 isoform A [Homo sapiens]
Length = 878
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/50 (46%), Positives = 30/50 (60%)
Query: 164 HNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
H + S+ RPT C C++ L G+ GL C+ CKF HKRCA R N+C
Sbjct: 265 HTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDC 314
Score = 47.4 bits (111), Expect = 8e-05
Identities = 19/44 (43%), Positives = 24/44 (54%)
Query: 170 SHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
S+ P +C+ C E L G+ GL C+ C HKRCA NNC
Sbjct: 145 SYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNC 188
>gi|120659782 protein kinase D2 isoform A [Homo sapiens]
Length = 878
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/50 (46%), Positives = 30/50 (60%)
Query: 164 HNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
H + S+ RPT C C++ L G+ GL C+ CKF HKRCA R N+C
Sbjct: 265 HTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDC 314
Score = 47.4 bits (111), Expect = 8e-05
Identities = 19/44 (43%), Positives = 24/44 (54%)
Query: 170 SHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
S+ P +C+ C E L G+ GL C+ C HKRCA NNC
Sbjct: 145 SYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNC 188
>gi|19923468 protein kinase D2 isoform A [Homo sapiens]
Length = 878
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/50 (46%), Positives = 30/50 (60%)
Query: 164 HNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
H + S+ RPT C C++ L G+ GL C+ CKF HKRCA R N+C
Sbjct: 265 HTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDC 314
Score = 47.4 bits (111), Expect = 8e-05
Identities = 19/44 (43%), Positives = 24/44 (54%)
Query: 170 SHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNC 213
S+ P +C+ C E L G+ GL C+ C HKRCA NNC
Sbjct: 145 SYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNC 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,095,493
Number of Sequences: 37866
Number of extensions: 2635784
Number of successful extensions: 39069
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 496
Number of HSP's successfully gapped in prelim test: 306
Number of HSP's that attempted gapping in prelim test: 26277
Number of HSP's gapped (non-prelim): 8958
length of query: 1214
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1100
effective length of database: 13,930,794
effective search space: 15323873400
effective search space used: 15323873400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.