Guide to the Human Genome
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Search of human proteins with 25188179

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25188179 voltage-dependent anion channel 3 isoform b [Homo
sapiens]
         (283 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25188179 voltage-dependent anion channel 3 isoform b [Homo sa...   582   e-166
gi|208879465 voltage-dependent anion channel 3 isoform a [Homo s...   577   e-165
gi|42476281 voltage-dependent anion channel 2 [Homo sapiens]          446   e-126
gi|113412878 PREDICTED: similar to voltage-dependent anion chann...   441   e-124
gi|169164151 PREDICTED: similar to voltage-dependent anion chann...   439   e-123
gi|169163967 PREDICTED: similar to voltage-dependent anion chann...   437   e-123
gi|4507879 voltage-dependent anion channel 1 [Homo sapiens]           409   e-114
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa...    29   5.3  
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa...    29   5.3  
gi|62234461 Notchless gene homolog isoform a [Homo sapiens]            29   5.3  
gi|110611231 chloride channel accessory 1 precursor [Homo sapiens]     28   9.1  

>gi|25188179 voltage-dependent anion channel 3 isoform b [Homo
           sapiens]
          Length = 283

 Score =  582 bits (1499), Expect = e-166
 Identities = 283/283 (100%), Positives = 283/283 (100%)

Query: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60
           MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET
Sbjct: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60

Query: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120
           KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR
Sbjct: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120

Query: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180
           DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL
Sbjct: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180

Query: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240
           HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA
Sbjct: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240

Query: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283
           SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA
Sbjct: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283


>gi|208879465 voltage-dependent anion channel 3 isoform a [Homo
           sapiens]
          Length = 284

 Score =  577 bits (1487), Expect = e-165
 Identities = 283/284 (99%), Positives = 283/284 (99%), Gaps = 1/284 (0%)

Query: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGV-EFSTSGHAYTDTGKASGNLE 59
           MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGV EFSTSGHAYTDTGKASGNLE
Sbjct: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVMEFSTSGHAYTDTGKASGNLE 60

Query: 60  TKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYK 119
           TKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYK
Sbjct: 61  TKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYK 120

Query: 120 RDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQ 179
           RDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQ
Sbjct: 121 RDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQ 180

Query: 180 LHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNN 239
           LHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNN
Sbjct: 181 LHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNN 240

Query: 240 ASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283
           ASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA
Sbjct: 241 ASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 284


>gi|42476281 voltage-dependent anion channel 2 [Homo sapiens]
          Length = 294

 Score =  446 bits (1148), Expect = e-126
 Identities = 208/283 (73%), Positives = 250/283 (88%)

Query: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60
           MC  P+Y DLGKAA+D+FNKG+GFG+VK+D+KTKSCSGVEFSTSG + TDTGK +G LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120
           KYK C YGLTFT+KWNTDNTLGTEI+ E+++ +GLKLT DT F PNTGKKSGK+K+SYKR
Sbjct: 72  KYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKR 131

Query: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180
           +C ++G +VD DF+GP I+G AV  +EGWLAGYQM+FD+AKSKL++NNFA+GY+  DFQL
Sbjct: 132 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 191

Query: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240
           HT+VNDGTEFGGSIYQKV E ++TS+NLAWT+G+N TRFGIAAKY LD   S+SAKVNN+
Sbjct: 192 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNS 251

Query: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283
           SLIG+GYTQTLRPGVKLTLSAL+DGK+ +AGGHKVGL  ELEA
Sbjct: 252 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 294


>gi|113412878 PREDICTED: similar to voltage-dependent anion channel
           2 [Homo sapiens]
          Length = 293

 Score =  441 bits (1135), Expect = e-124
 Identities = 208/283 (73%), Positives = 249/283 (87%), Gaps = 1/283 (0%)

Query: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60
           MC  P+Y DLGKAA+D+FNKG+GFG+VK+D+KTKSCSGVEFSTSG + TDTGK +G LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120
           KYK C YGLTFT+KWNTDNTLGTEI+ E+++ +GLKLT DT F PNTGKKSGK+K SYKR
Sbjct: 72  KYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIK-SYKR 130

Query: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180
           +C ++G +VD DF+GP I+G AV  +EGWLAGYQM+FD+AKSKL++NNFA+GY+  DFQL
Sbjct: 131 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 190

Query: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240
           HT+VNDGTEFGGSIYQKV E ++TS+NLAWT+G+N TRFGIAAKY LD   S+SAKVNN+
Sbjct: 191 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNS 250

Query: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283
           SLIG+GYTQTLRPGVKLTLSAL+DGK+ +AGGHKVGL  ELEA
Sbjct: 251 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 293


>gi|169164151 PREDICTED: similar to voltage-dependent anion channel
           2 [Homo sapiens]
          Length = 293

 Score =  439 bits (1129), Expect = e-123
 Identities = 207/283 (73%), Positives = 248/283 (87%), Gaps = 1/283 (0%)

Query: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60
           MC  P+Y DLGKAA+D+FNKG+GFG+VK+D+KTKSCSGVEFSTSG + TDTGK +G LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120
           KYK C YGLT T+KWNTDNTLGTEI+ E+++ +GLKLT DT F PNTGKKSGK+K SYKR
Sbjct: 72  KYKWCEYGLTITEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIK-SYKR 130

Query: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180
           +C ++G +VD DF+GP I+G AV  +EGWLAGYQM+FD+AKSKL++NNFA+GY+  DFQL
Sbjct: 131 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 190

Query: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240
           HT+VNDGTEFGGSIYQKV E ++TS+NLAWT+G+N TRFGIAAKY LD   S+SAKVNN+
Sbjct: 191 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNS 250

Query: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283
           SLIG+GYTQTLRPGVKLTLSAL+DGK+ +AGGHKVGL  ELEA
Sbjct: 251 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 293


>gi|169163967 PREDICTED: similar to voltage-dependent anion channel
           2 [Homo sapiens]
          Length = 293

 Score =  437 bits (1123), Expect = e-123
 Identities = 206/283 (72%), Positives = 247/283 (87%), Gaps = 1/283 (0%)

Query: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60
           MC  P+Y DLGKAA+D+FNKG+GFG+VK+D+KTKSCSGVEFSTSG + TDTGK +G LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120
           KYK C YGLT T+KWNTDNTLGTEI+ E+++ +GLKLT DT F PNTGKKSGK+K SYKR
Sbjct: 72  KYKWCEYGLTITEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIK-SYKR 130

Query: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180
           +C ++G +VD DF+GP I+G AV  +EGWLAGYQM+FD+AKSKL++NNFA+GY+  DFQL
Sbjct: 131 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 190

Query: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240
           HT+VNDGTEFGGSIYQKV E ++TS+NLAWT+G+N TRFGIAAKY  D   S+SAKVNN+
Sbjct: 191 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQSDPTASISAKVNNS 250

Query: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283
           SLIG+GYTQTLRPGVKLTLSAL+DGK+ +AGGHKVGL  ELEA
Sbjct: 251 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 293


>gi|4507879 voltage-dependent anion channel 1 [Homo sapiens]
          Length = 283

 Score =  409 bits (1050), Expect = e-114
 Identities = 191/283 (67%), Positives = 242/283 (85%)

Query: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60
           M   PTY DLGK+A+DVF KGYGFG++K+DLKTKS +G+EF++SG A T+T K +G+LET
Sbjct: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60

Query: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120
           KY+   YGLTFT+KWNTDNTLGTEI+ E++LA GLKLT D+ F PNTGKK+ K+K  YKR
Sbjct: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120

Query: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180
           +  ++G ++D D +GP+I G  VL +EGWLAGYQM+F+TAKS+++Q+NFA+GYK  +FQL
Sbjct: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180

Query: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240
           HT+VNDGTEFGGSIYQKVN+K+ET++NLAWTAG++NTRFGIAAKY +D     SAKVNN+
Sbjct: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240

Query: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283
           SLIGLGYTQTL+PG+KLTLSAL+DGKN +AGGHK+GLG E +A
Sbjct: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283


>gi|46049092 nebulin-related anchoring protein isoform C [Homo
           sapiens]
          Length = 1695

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 86  SWENKLAEGLKLTLDTI-FVPNTGKKSGKLKASYKRD 121
           SWEN+ A+G +L LD++ F+    K+    +  YK D
Sbjct: 754 SWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKED 790


>gi|46049105 nebulin-related anchoring protein isoform S [Homo
           sapiens]
          Length = 1730

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 86  SWENKLAEGLKLTLDTI-FVPNTGKKSGKLKASYKRD 121
           SWEN+ A+G +L LD++ F+    K+    +  YK D
Sbjct: 789 SWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKED 825


>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
          Length = 485

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 10/96 (10%)

Query: 33  TKSCSGVEFSTSGHAYTDTGK--ASGNLETKYKVCNYGLT---FTQKWNTDNTLGTEISW 87
           T S  G   +    A++ TGK  ASG+ +T  +  +       FT K +    L   ISW
Sbjct: 107 TSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS--ISW 164

Query: 88  E---NKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120
                KLA G K     ++ P+TGK+ G+  A + +
Sbjct: 165 SPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSK 200


>gi|110611231 chloride channel accessory 1 precursor [Homo sapiens]
          Length = 914

 Score = 28.1 bits (61), Expect = 9.1
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 9/47 (19%)

Query: 206 INLAWTAGSNNTRFGIAAKYMLDCRTSL---------SAKVNNASLI 243
           INL WTA  ++   G A KY++   TS+         S +VN  +LI
Sbjct: 769 INLTWTAPGDDYDHGTAHKYIIRISTSILDLRDKFNESLQVNTTALI 815


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,070,391
Number of Sequences: 37866
Number of extensions: 384627
Number of successful extensions: 649
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 628
Number of HSP's gapped (non-prelim): 13
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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