Search of human proteins with 24475816

Search of human proteins with 24475816

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]                   652   0.0  
gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]         348   3e-96
gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]            317   1e-86
gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]     63   3e-10
gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]                  55   6e-08
gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]                 33   0.42 
gi|14589896 megalencephalic leukoencephalopathy with subcortical...    29   4.6  
gi|21237732 megalencephalic leukoencephalopathy with subcortical...    29   4.6  
gi|5902148 uroplakin 1A [Homo sapiens]                                 29   4.6  
gi|46409292 dpy-19-like 3 [Homo sapiens]                               28   7.9  

>gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]
          Length = 308

 Score =  652 bits (1681), Expect = 0.0
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLK 60
           MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLK
Sbjct: 1   MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLK 60

Query: 61  DEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFT 120
           DEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFT
Sbjct: 61  DEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFT 120

Query: 121 SSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN 180
           SSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN
Sbjct: 121 SSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN 180

Query: 181 HPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLF 240
           HPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLF
Sbjct: 181 HPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLF 240

Query: 241 LLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLR 300
           LLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLR
Sbjct: 241 LLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLR 300

Query: 301 MPIIPFLL 308
           MPIIPFLL
Sbjct: 301 MPIIPFLL 308


>gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]
          Length = 363

 Score =  348 bits (894), Expect = 3e-96
 Identities = 158/306 (51%), Positives = 210/306 (68%), Gaps = 1/306 (0%)

Query: 3   HYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLKDE 62
           H+E+EI DA+TR+++C LDKV   +TI ++K  F K  P+WYP+R  L+L+  G  LKD 
Sbjct: 59  HFEIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDY 118

Query: 63  DVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFTSS 122
             +Q +   +  TLY  DLG Q+SW TVFL EY GPL IYLLFY R+P IY  K      
Sbjct: 119 ITIQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPCIYDGKESARRL 178

Query: 123 RHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYINHP 182
           RH VVHLAC CH  HYI+ LLETLFVH+ S G  PL+N+  +C +YWGF +W+AYYINHP
Sbjct: 179 RHPVVHLACFCHCIHYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAYYINHP 238

Query: 183 LYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLL 242
           LYTPP++G +Q+ ++   F+IC+ GN  I++ L      G+     P P  NPFTW+F L
Sbjct: 239 LYTPPSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGNNA-CFPSPNYNPFTWMFFL 297

Query: 243 VSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMP 302
           VSCPNYTYE+GSWI F +MTQ LPV +F+L+   QM++WA+ KH+ YL++F  Y   +  
Sbjct: 298 VSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSA 357

Query: 303 IIPFLL 308
           +IPF+L
Sbjct: 358 MIPFIL 363


>gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]
          Length = 166

 Score =  317 bits (811), Expect = 1e-86
 Identities = 146/147 (99%), Positives = 147/147 (100%)

Query: 162 FKNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPA 221
           F+NCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPA
Sbjct: 20  FQNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPA 79

Query: 222 GSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIW 281
           GSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIW
Sbjct: 80  GSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIW 139

Query: 282 AKGKHRSYLKEFRDYPPLRMPIIPFLL 308
           AKGKHRSYLKEFRDYPPLRMPIIPFLL
Sbjct: 140 AKGKHRSYLKEFRDYPPLRMPIIPFLL 166


>gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]
          Length = 254

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 9/149 (6%)

Query: 161 IFKNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHM--ALRDL 218
           I +   +  G      YY+ +    P  +    ++ +L +F+       +IH    LR L
Sbjct: 112 ILRGTAFCTGNGVLQGYYLIYCAEYPDGWYTD-IRFSLGVFLFILGMGINIHSDYILRQL 170

Query: 219 RPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQM 278
           R  G  + +IP         LF  VS  N+  E+  WIG+A+ T  LP   F+      +
Sbjct: 171 RKPGEISYRIPQGG------LFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFL 224

Query: 279 TIWAKGKHRSYLKEFRDYPPLRMPIIPFL 307
            + A   HR YLK F DYP  R  +IPF+
Sbjct: 225 GLRAFHHHRFYLKMFEDYPKSRKALIPFI 253


>gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]
          Length = 259

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 7/131 (5%)

Query: 178 YINH-PLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPF 236
           Y++H  +Y        +  +   +++   L N      LR+LR  G    KIP       
Sbjct: 134 YLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGG---- 189

Query: 237 TWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDY 296
             LF  V+  NY  E+  W G+A+ +  +  A F+   F  ++  AK  H  YL++F +Y
Sbjct: 190 --LFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEY 247

Query: 297 PPLRMPIIPFL 307
           P  R  IIPFL
Sbjct: 248 PKFRKIIIPFL 258


>gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]
          Length = 318

 Score = 32.7 bits (73), Expect = 0.42
 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 3/114 (2%)

Query: 196 LALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSW 255
           L + +F+      +  H+ L +LR   +    I    + PF   F  VS PNY  E+  +
Sbjct: 205 LGMMMFIWSSAHQYKCHVILGNLRKNKAGV-VIHCNHRIPFGDWFEYVSSPNYLAELMIY 263

Query: 256 IGFAIMTQCLPVALFSLVG--FTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFL 307
           +  A+      +  + +V   F    + A   H+ Y  +F  YP  R   +PFL
Sbjct: 264 VSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFL 317


>gi|14589896 megalencephalic leukoencephalopathy with subcortical
           cysts 1 gene product [Homo sapiens]
          Length = 377

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 237 TWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSY-----LK 291
           T+ ++LV+C  +   + S +     ++CL   L ++   T   ++    + S+     ++
Sbjct: 231 TFFWILVAC--FPSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVE 288

Query: 292 EFRDYPPLRMPIIPFLL 308
            F+DYPP   P    LL
Sbjct: 289 MFKDYPPAIKPSYDVLL 305


>gi|21237732 megalencephalic leukoencephalopathy with subcortical
           cysts 1 gene product [Homo sapiens]
          Length = 377

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 237 TWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSY-----LK 291
           T+ ++LV+C  +   + S +     ++CL   L ++   T   ++    + S+     ++
Sbjct: 231 TFFWILVAC--FPSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVE 288

Query: 292 EFRDYPPLRMPIIPFLL 308
            F+DYPP   P    LL
Sbjct: 289 MFKDYPPAIKPSYDVLL 305


>gi|5902148 uroplakin 1A [Homo sapiens]
          Length = 258

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 13/32 (40%), Positives = 21/32 (65%), Gaps = 1/32 (3%)

Query: 247 NYTYEVGSWIGFAIMTQCLPVALFSLVGFTQM 278
           +YT+ + SW GFAI+   LPV L ++  +T +
Sbjct: 228 SYTWGI-SWFGFAILMWTLPVMLIAMYFYTML 258


>gi|46409292 dpy-19-like 3 [Homo sapiens]
          Length = 716

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 11/107 (10%)

Query: 53  DPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFI 112
           D K +S+K  ++LQ++ +       ++++   I +  + + +Y  P++ Y+   F +  I
Sbjct: 117 DNKTESMKTINLLQRMNI-------YQEVFLSILYRVLPIQKYLEPVYFYIYTLFGLQAI 169

Query: 113 YGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLR 159
           Y      TS   +   L+ +  +F Y+   ++T  V      T+PLR
Sbjct: 170 YVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRV----EFTIPLR 212


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.142    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,487,080
Number of Sequences: 37866
Number of extensions: 538408
Number of successful extensions: 1154
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1146
Number of HSP's gapped (non-prelim): 11
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.