Guide to the Human Genome
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Search of human proteins with 24475814

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24475814 polymerase (RNA) III (DNA directed) polypeptide H
(22.9kD) isoform a [Homo sapiens]
         (204 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|65301161 polymerase (RNA) III (DNA directed) polypeptide H (2...   423   e-119
gi|24475814 polymerase (RNA) III (DNA directed) polypeptide H (2...   423   e-119
gi|65301135 polymerase (RNA) III (DNA directed) polypeptide H (2...   345   2e-95
gi|4505947 DNA directed RNA polymerase II polypeptide G [Homo sa...    38   0.007
gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap...    31   0.83 
gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap...    31   0.83 
gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sap...    31   0.83 
gi|4507545 G protein-coupled receptor 137B [Homo sapiens]              31   0.83 
gi|145312265 endoplasmic reticulum to nucleus signalling 2 [Homo...    30   1.4  
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi...    29   2.4  
gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens]     28   5.4  
gi|224589071 BMS1-like, ribosome assembly protein [Homo sapiens]       28   7.1  
gi|210031233 PR domain containing 6 [Homo sapiens]                     28   7.1  
gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens]         28   7.1  
gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens]           28   7.1  
gi|38505161 tudor domain containing 1 [Homo sapiens]                   27   9.2  
gi|31542509 ADP-dependent glucokinase [Homo sapiens]                   27   9.2  
gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]     27   9.2  
gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens]     27   9.2  

>gi|65301161 polymerase (RNA) III (DNA directed) polypeptide H
           (22.9kD) isoform a [Homo sapiens]
          Length = 204

 Score =  423 bits (1088), Expect = e-119
 Identities = 204/204 (100%), Positives = 204/204 (100%)

Query: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60
           MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF
Sbjct: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60

Query: 61  PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF 120
           PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF
Sbjct: 61  PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF 120

Query: 121 DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK 180
           DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK
Sbjct: 121 DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK 180

Query: 181 EAPYTLVGSISEPGLGLLSWWTSN 204
           EAPYTLVGSISEPGLGLLSWWTSN
Sbjct: 181 EAPYTLVGSISEPGLGLLSWWTSN 204


>gi|24475814 polymerase (RNA) III (DNA directed) polypeptide H
           (22.9kD) isoform a [Homo sapiens]
          Length = 204

 Score =  423 bits (1088), Expect = e-119
 Identities = 204/204 (100%), Positives = 204/204 (100%)

Query: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60
           MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF
Sbjct: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60

Query: 61  PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF 120
           PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF
Sbjct: 61  PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF 120

Query: 121 DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK 180
           DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK
Sbjct: 121 DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK 180

Query: 181 EAPYTLVGSISEPGLGLLSWWTSN 204
           EAPYTLVGSISEPGLGLLSWWTSN
Sbjct: 181 EAPYTLVGSISEPGLGLLSWWTSN 204


>gi|65301135 polymerase (RNA) III (DNA directed) polypeptide H
           (22.9kD) isoform b [Homo sapiens]
          Length = 175

 Score =  345 bits (885), Expect = 2e-95
 Identities = 175/204 (85%), Positives = 175/204 (85%), Gaps = 29/204 (14%)

Query: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60
           MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF
Sbjct: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60

Query: 61  PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF 120
           PGDGASHTK                             VSLGFFDDILIPPESLQQPAKF
Sbjct: 61  PGDGASHTK-----------------------------VSLGFFDDILIPPESLQQPAKF 91

Query: 121 DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK 180
           DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK
Sbjct: 92  DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK 151

Query: 181 EAPYTLVGSISEPGLGLLSWWTSN 204
           EAPYTLVGSISEPGLGLLSWWTSN
Sbjct: 152 EAPYTLVGSISEPGLGLLSWWTSN 175


>gi|4505947 DNA directed RNA polymerase II polypeptide G [Homo
           sapiens]
          Length = 172

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 30/153 (19%), Positives = 62/153 (40%), Gaps = 5/153 (3%)

Query: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60
           MF  + +   + + P  F   L +++ ++L  ++        G  I +  I  +    + 
Sbjct: 1   MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQ 60

Query: 61  PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF 120
           PG G     V ++ +VF PF  E++   +   +  G+   +G      I   S+    +F
Sbjct: 61  PGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPM-SCFISRHSIPSEMEF 119

Query: 121 DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVV 153
           D       ++   E    D+ +   +EIR ++V
Sbjct: 120 DPNSNPPCYKTMDE----DIVIQQDDEIRLKIV 148


>gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo
           sapiens]
          Length = 1826

 Score = 30.8 bits (68), Expect = 0.83
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 7/78 (8%)

Query: 106 DILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDE----SFVDTS 161
           DI+   +  + P K +EA  +   E +  E   D+  D G   R+   D     SFVD +
Sbjct: 381 DIIAKSQGSRDPPKVEEAHYITTHEIQLSEVEQDMDFDVGLASRWDFEDNNVIYSFVDYA 440

Query: 162 PTGPSS---ADATTSSEE 176
             G S     D T+ +EE
Sbjct: 441 SFGGSDETPGDITSLTEE 458


>gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo
           sapiens]
          Length = 1826

 Score = 30.8 bits (68), Expect = 0.83
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 7/78 (8%)

Query: 106 DILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDE----SFVDTS 161
           DI+   +  + P K +EA  +   E +  E   D+  D G   R+   D     SFVD +
Sbjct: 381 DIIAKSQGSRDPPKVEEAHYITTHEIQLSEVEQDMDFDVGLASRWDFEDNNVIYSFVDYA 440

Query: 162 PTGPSS---ADATTSSEE 176
             G S     D T+ +EE
Sbjct: 441 SFGGSDETPGDITSLTEE 458


>gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo
           sapiens]
          Length = 1826

 Score = 30.8 bits (68), Expect = 0.83
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 7/78 (8%)

Query: 106 DILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDE----SFVDTS 161
           DI+   +  + P K +EA  +   E +  E   D+  D G   R+   D     SFVD +
Sbjct: 381 DIIAKSQGSRDPPKVEEAHYITTHEIQLSEVEQDMDFDVGLASRWDFEDNNVIYSFVDYA 440

Query: 162 PTGPSS---ADATTSSEE 176
             G S     D T+ +EE
Sbjct: 441 SFGGSDETPGDITSLTEE 458


>gi|4507545 G protein-coupled receptor 137B [Homo sapiens]
          Length = 399

 Score = 30.8 bits (68), Expect = 0.83
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 1   MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF 60
           +F+LV +   V +    +ERK+  S+   +N  L   V+  V L ICL+ I+K+  A ++
Sbjct: 168 VFLLVNLTCAVLVKTGNWERKVIVSVRVAINDTLF--VLCAVSLSICLYKISKMSLANIY 225


>gi|145312265 endoplasmic reticulum to nucleus signalling 2 [Homo
           sapiens]
          Length = 974

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 5/56 (8%)

Query: 97  VHVSLGFFDDILIPPESLQQPAKFDE-----AEQVWVWEYETEEGAHDLYMDTGEE 147
           VH +LG       PPE+ Q PA F E      E++W  E   EE   D Y+  G +
Sbjct: 424 VHPTLGSGTAETRPPENTQAPAFFLELLSLSREKLWDSELHPEEKTPDSYLGLGPQ 479


>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
           sapiens]
          Length = 1205

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 91  GCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVW-----EYETEEGAHDLYMDTG 145
           G  PE   +   ++  I  PPE L    ++D  E+   W     E    +G   +  DT 
Sbjct: 125 GIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVSADTF 184

Query: 146 EEIRFRVVDESFVDTSPTG 164
           E +  R+  ES++++  +G
Sbjct: 185 ELLVDRLEKESYLESRSSG 203


>gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens]
          Length = 412

 Score = 28.1 bits (61), Expect = 5.4
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 6/76 (7%)

Query: 6   EMVDTVRIPPWQFERKLNDSIAEEL--NKKLANKVVY--NVGLCICLFDITKLEDAY-VF 60
           E     R P W  +R L    A+EL    +   KVV   ++G  +C+ D   +  A+ + 
Sbjct: 337 EQYMNTRCPAW-CDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIM 395

Query: 61  PGDGASHTKVHFRCVV 76
           PG G  H  VH  CVV
Sbjct: 396 PGAGKPHAHVHKCCVV 411


>gi|224589071 BMS1-like, ribosome assembly protein [Homo sapiens]
          Length = 1282

 Score = 27.7 bits (60), Expect = 7.1
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 6/84 (7%)

Query: 123 AEQVWVWEYETEEG----AHDLYMDTGEEIRFRVVDESFVDTSPT-GPSS-ADATTSSEE 176
           AE+V+  E E+EE     A +   +  E IR ++   S V +    GP +  D T+  E 
Sbjct: 584 AEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIEN 643

Query: 177 LPKKEAPYTLVGSISEPGLGLLSW 200
           L K+E  Y    + S+   G L W
Sbjct: 644 LLKEEEDYKEENNDSKETSGALKW 667


>gi|210031233 PR domain containing 6 [Homo sapiens]
          Length = 595

 Score = 27.7 bits (60), Expect = 7.1
 Identities = 14/46 (30%), Positives = 24/46 (52%), Gaps = 3/46 (6%)

Query: 101 LGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGE 146
           +G F  +L+PPE +Q  A  +      +WE   ++G    ++D GE
Sbjct: 274 IGPFQGVLLPPEKVQAGAVRNTQH---LWEIYDQDGTLQHFIDGGE 316


>gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens]
          Length = 446

 Score = 27.7 bits (60), Expect = 7.1
 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 6/54 (11%)

Query: 44 LCICLFDITKLEDAYVF-PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEG 96
          + +C F +  L + Y   P D +S   V+F  +     L++IL  + K C+P G
Sbjct: 32 ITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAI-----LEQILSHRFKACAPAG 80


>gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens]
          Length = 405

 Score = 27.7 bits (60), Expect = 7.1
 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 6/54 (11%)

Query: 44 LCICLFDITKLEDAYVF-PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEG 96
          + +C F +  L + Y   P D +S   V+F  +     L++IL  + K C+P G
Sbjct: 32 ITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAI-----LEQILSHRFKACAPAG 80


>gi|38505161 tudor domain containing 1 [Homo sapiens]
          Length = 1189

 Score = 27.3 bits (59), Expect = 9.2
 Identities = 20/63 (31%), Positives = 24/63 (38%), Gaps = 22/63 (34%)

Query: 22  LNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGA------------SHTK 69
           LN S+AE   +KL N     +G   C F          F GDG+             H K
Sbjct: 745 LNKSLAEHCQQKLPNGFKAEIGQPCCAF----------FAGDGSWYRALVKEILPNGHVK 794

Query: 70  VHF 72
           VHF
Sbjct: 795 VHF 797


>gi|31542509 ADP-dependent glucokinase [Homo sapiens]
          Length = 496

 Score = 27.3 bits (59), Expect = 9.2
 Identities = 12/33 (36%), Positives = 19/33 (57%)

Query: 88  KIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF 120
           K+  C P G  +     D++ +PPESLQ+  +F
Sbjct: 174 KVLLCGPVGPKLHELLDDNVFVPPESLQEVDEF 206


>gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]
          Length = 902

 Score = 27.3 bits (59), Expect = 9.2
 Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 30/120 (25%)

Query: 66  SHTKVHFRCVVFHPFLDEILIGKI-----------KGCSPEGVHV-SLGFF--------- 104
           S +KVHF      P+  ++LIGK            KG    G+H+ S+G +         
Sbjct: 526 SCSKVHFHL----PYRWQMLIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSC 581

Query: 105 DDI----LIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDT 160
           D      L  P S+ +PA      + W+W ++ E G    Y +  ++ +   VD S++++
Sbjct: 582 DSFPIRRLSTPSSVTKPANSVFTTK-WIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLES 640


>gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens]
          Length = 699

 Score = 27.3 bits (59), Expect = 9.2
 Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 30/120 (25%)

Query: 66  SHTKVHFRCVVFHPFLDEILIGKI-----------KGCSPEGVHV-SLGFF--------- 104
           S +KVHF      P+  ++LIGK            KG    G+H+ S+G +         
Sbjct: 526 SCSKVHFHL----PYRWQMLIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSC 581

Query: 105 DDI----LIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDT 160
           D      L  P S+ +PA      + W+W ++ E G    Y +  ++ +   VD S++++
Sbjct: 582 DSFPIRRLSTPSSVTKPANSVFTTK-WIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLES 640


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,615,967
Number of Sequences: 37866
Number of extensions: 391162
Number of successful extensions: 1002
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 996
Number of HSP's gapped (non-prelim): 20
length of query: 204
length of database: 18,247,518
effective HSP length: 97
effective length of query: 107
effective length of database: 14,574,516
effective search space: 1559473212
effective search space used: 1559473212
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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