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Search of human proteins with 24308069
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308069 zinc finger protein 521 [Homo sapiens]
(1311 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308069 zinc finger protein 521 [Homo sapiens] 2764 0.0
gi|46359075 zinc finger protein 423 [Homo sapiens] 1680 0.0
gi|118600985 zinc finger protein 91 [Homo sapiens] 268 3e-71
gi|6005976 zinc finger protein 208 [Homo sapiens] 260 7e-69
gi|122937213 zinc finger protein 99 [Homo sapiens] 251 4e-66
gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens] 249 9e-66
gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens] 249 9e-66
gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo ... 249 9e-66
gi|210031219 zinc finger protein 845 [Homo sapiens] 239 1e-62
gi|119120877 zinc finger protein 721 [Homo sapiens] 228 3e-59
gi|157167158 zinc finger protein 808 [Homo sapiens] 226 8e-59
gi|154800445 zinc finger protein 62 homolog [Homo sapiens] 226 1e-58
gi|156627573 zinc finger protein 836 [Homo sapiens] 214 4e-55
gi|23308729 zinc finger protein 268 [Homo sapiens] 204 6e-52
gi|40217792 zinc finger protein 585A [Homo sapiens] 203 1e-51
gi|22749331 zinc finger protein 585A [Homo sapiens] 203 1e-51
gi|25014093 zinc finger protein 585B [Homo sapiens] 198 2e-50
gi|68303809 zinc finger protein 43 [Homo sapiens] 197 6e-50
gi|172072608 zinc finger protein 624 [Homo sapiens] 195 3e-49
gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens] 195 3e-49
gi|54291708 zinc finger protein 780B [Homo sapiens] 191 4e-48
gi|156547246 zinc finger protein 160 [Homo sapiens] 191 5e-48
gi|38788302 zinc finger protein 160 [Homo sapiens] 191 5e-48
gi|38788288 zinc finger protein 160 [Homo sapiens] 191 5e-48
gi|138175817 zinc finger protein 236 [Homo sapiens] 187 4e-47
gi|55769537 zinc finger protein 658 [Homo sapiens] 184 5e-46
gi|62243640 zinc finger protein 107 [Homo sapiens] 179 2e-44
gi|7706775 zinc finger protein 107 [Homo sapiens] 179 2e-44
gi|222831664 zinc finger protein 184 [Homo sapiens] 177 8e-44
gi|150378520 zinc finger protein 594 [Homo sapiens] 177 8e-44
>gi|24308069 zinc finger protein 521 [Homo sapiens]
Length = 1311
Score = 2764 bits (7166), Expect = 0.0
Identities = 1311/1311 (100%), Positives = 1311/1311 (100%)
Query: 1 MSRRKQAKPRSLKDPNCKLEDKTEDGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLS 60
MSRRKQAKPRSLKDPNCKLEDKTEDGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLS
Sbjct: 1 MSRRKQAKPRSLKDPNCKLEDKTEDGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLS 60
Query: 61 DITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPC 120
DITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPC
Sbjct: 61 DITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPC 120
Query: 121 QFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECD 180
QFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECD
Sbjct: 121 QFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECD 180
Query: 181 AAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDW 240
AAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDW
Sbjct: 181 AAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDW 240
Query: 241 KMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHM 300
KMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHM
Sbjct: 241 KMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHM 300
Query: 301 EQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPD 360
EQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPD
Sbjct: 301 EQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPD 360
Query: 361 SNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAV 420
SNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAV
Sbjct: 361 SNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAV 420
Query: 421 LQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCN 480
LQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCN
Sbjct: 421 LQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCN 480
Query: 481 FCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLS 540
FCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLS
Sbjct: 481 FCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLS 540
Query: 541 GSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKK 600
GSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKK
Sbjct: 541 GSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKK 600
Query: 601 SRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV 660
SRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV
Sbjct: 601 SRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV 660
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV
Sbjct: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG
Sbjct: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
Query: 781 KVHKCIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTP 840
KVHKCIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTP
Sbjct: 781 KVHKCIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTP 840
Query: 841 NCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETL 900
NCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETL
Sbjct: 841 NCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETL 900
Query: 901 LQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYM 960
LQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYM
Sbjct: 901 LQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYM 960
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGF 1020
CPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGF
Sbjct: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGF 1020
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDL 1080
RCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDL
Sbjct: 1021 RCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDL 1080
Query: 1081 VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRC 1140
VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRC
Sbjct: 1081 VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRC 1140
Query: 1141 SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC 1200
SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC
Sbjct: 1141 SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC 1200
Query: 1201 QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV 1260
QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV
Sbjct: 1201 QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV 1260
Query: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS 1311
CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS
Sbjct: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS 1311
>gi|46359075 zinc finger protein 423 [Homo sapiens]
Length = 1284
Score = 1680 bits (4351), Expect = 0.0
Identities = 822/1309 (62%), Positives = 988/1309 (75%), Gaps = 68/1309 (5%)
Query: 14 DPNC--KLEDKTEDGEALDCKK-RPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQC 70
+P C K ED ++ ++ R ED E++EDE++++CD C Q FESL+D+T+H+ ++C
Sbjct: 31 EPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRC 90
Query: 71 QLTDGVDVEDDPTCSWPASSPSSKDQTSPSH--GEGCDFG--EEEGGPGLPYPCQFCDKS 126
D +DDP SW ASSPSSKD SP+ G+GCD G EEEGG GLPYPCQFCDKS
Sbjct: 91 P----GDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKS 146
Query: 127 FSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRS 186
F RLSYLK HEQ HSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC EC+AAFSRS
Sbjct: 147 FIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRS 206
Query: 187 DHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQ 246
DHLKIHLKTH+S+KP+KC +C+RGF S+SSL HMQ H++NK+ ++ E KD
Sbjct: 207 DHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHL---AKSEKEAKKDDF 263
Query: 247 KCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSG 306
C CE+ F E+L+KH+ HP+ S ++A LQC++C E+FV+E +L+ H+ Q H+
Sbjct: 264 MCDYCEDTFSQTEELEKHVLTRHPQLS---EKADLQCIHCPEVFVDENTLLAHIHQAHAN 320
Query: 307 EKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVD 366
+K + C +C E F +VE +Y H+DSH+QP+S NHS SP V S+SS TPDS+ SV+
Sbjct: 321 QK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVE 379
Query: 367 SSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLK 426
+ ++ + RG+K+ T KV YSC YC+K+ F+SLAVL+IHLK
Sbjct: 380 RGSTPDST--LKPLRGQKKMRDDGQGWT-------KVVYSCPYCSKRDFNSLAVLEIHLK 430
Query: 427 TMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD-PGLIVSAMPAIVYQCNFCSEV 485
T+H DKP+Q+H CQ CL+ +P+LYNLNEH++++H+ P + + A + CN+C E+
Sbjct: 431 TIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISA--FHCNYCPEM 488
Query: 486 VNDLNTLQEHIRCSHGFANPAAKD-SNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRF 544
D+N+LQEHIR SH N D +NAFFC C MGFLT+SSL EHI+Q HC + ++
Sbjct: 489 FADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKL 548
Query: 545 GSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRAL 604
SPV+ P + +EVYSC YCTNSPIF S+LKL KHIKENHKNIPLA H+ K
Sbjct: 549 ESPVV-QPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLA----HSKKSKAEQ 603
Query: 605 SPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKL 664
SP+S +E +S K + A + GEY CNQC K+++ +SFQTHLK HL+ +L K
Sbjct: 604 SPVSS-DVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
Query: 665 TCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRC 724
CPQC ++F +QESLL+H+T+H+M TST+Y+CESCDKQF+SVDDLQKHLLDMHTFV + C
Sbjct: 663 ACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHC 722
Query: 725 TLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHK 784
TLCQEVFDSKVSIQ+HLAVKHSNEKK+YRCT+CNWDFR E DLQ+HVKH+HL N K HK
Sbjct: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
Query: 785 CIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGT 844
CIFCGE+F TEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVF+ T N
Sbjct: 783 CIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTA 842
Query: 845 NGASEQVQK--EEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQ 902
NG K E +LQ +L + E+ NSH+ SE+DVD SEPMYGCDICGAAYTME LLQ
Sbjct: 843 NGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQ 902
Query: 903 NHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCP 962
NH+LRDHNIRPGE +KKAE IKG++KCNVCSRTFFSENGLREH+QTH GP KHYMCP
Sbjct: 903 NHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCP 962
Query: 963 ICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRC 1022
ICGERFPSLLTLTEHKVTHSKSLDTG CRICKMPLQSEEEF+EHCQMHPDLRNSLTGFRC
Sbjct: 963 ICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRC 1022
Query: 1023 VVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK 1082
VVCMQTVTSTLELKIHGTFHMQK GS+ ++ GQ +QKLYKCA CLKEFRSKQDLVK
Sbjct: 1023 VVCMQTVTSTLELKIHGTFHMQKLA-GSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK 1081
Query: 1083 LDINGLPYGLCAGCVNLSKSASPGINVPP-GTNRPGLGQNENLSAIEGKGKVGGLKTRCS 1141
LD+NGLPYGLCAGC+ S + G PP +RP G RC
Sbjct: 1082 LDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAG------------------LRCP 1123
Query: 1142 SCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQ 1201
C+VKFES +L++H+Q HR+L P+++ + K Q SP+PR KKTYQCIKCQ
Sbjct: 1124 ECSVKFESAEDLESHMQVDHRDLTPETSGPR-KGTQTSPVPR--------KKTYQCIKCQ 1174
Query: 1202 MVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVC 1261
M F NE +IQ+HVANHMI+EG+NHECKLC+Q FDSPAKL CHLIEHSFEGMGGTFKCPVC
Sbjct: 1175 MTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVC 1234
Query: 1262 FTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHS 1310
FTVFVQANKLQQHIF+ HGQEDKIYDC+QCPQKFFFQTELQNHTM+QH+
Sbjct: 1235 FTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHA 1283
Score = 172 bits (435), Expect = 2e-42
Identities = 195/806 (24%), Positives = 298/806 (36%), Gaps = 157/806 (19%)
Query: 46 VHSCDSCLQ--VFESLSDITEH-KINQCQL---------TDGVDVEDDPTCSWPASSPSS 93
V+SC C +F S+ +T+H K N + + V D S P S
Sbjct: 562 VYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLS 621
Query: 94 KDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFK--CTYC 151
S S+GE YPC CD FS + H + H + L K C C
Sbjct: 622 ASANSISNGE--------------YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC 667
Query: 152 SRLFKHKRSRDRHIKLH--TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRR 209
F + S +H+ +H T Y C CD FS D L+ HL + Y C +C+
Sbjct: 668 KEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQE 727
Query: 210 GFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECH 269
F S S+ H+ V N+ K +C+ C F DLQ H+ H
Sbjct: 728 VFDSKVSIQVHLAVKHSNE--------------KKMYRCTACNWDFRKEADLQVHVKHSH 773
Query: 270 PECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHM 329
A +C++C E F E L H+ HS KK +C CS++FH + L H+
Sbjct: 774 L----GNPAKAHKCIFCGETFSTEVELQCHIT-THS--KKYNCKFCSKAFHAIILLEKHL 826
Query: 330 -DSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQ 388
+ H ++ + + + V T + D M+ P P S A++
Sbjct: 827 REKHCVFDAATENGTANGVPPMATKKAEPA-------DLQGMLLKNPEAPNSH---EASE 876
Query: 389 QTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQ------------- 435
D + P Y C C ++ +LQ H H +P +
Sbjct: 877 DDVDASEPM-------YGCDICGAA-YTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKG 928
Query: 436 AHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEH 495
+H C C S L EHL Q H PA Y C C E L TL EH
Sbjct: 929 SHKCNVCSRTFFSENGLREHL-QTHRG----------PAKHYMCPICGERFPSLLTLTEH 977
Query: 496 IRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFG-------SPV 548
+ +H +K + C C M ++ EH Q+H DL S G V
Sbjct: 978 -KVTH------SKSLDTGTCRICKMPLQSEEEFIEHC-QMHPDLRNSLTGFRCVVCMQTV 1029
Query: 549 LGTPKEPV-----VEVYSCSYCTNSPIFNSVLKLNK------HIKENHKNIPLALNYIHN 597
T + + ++ + S +SP + KL K + + L +N +
Sbjct: 1030 TSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPY 1089
Query: 598 GKKSRALSPLSPVAIEQTSLKMMQAVGGAPA----RPTGEYICNQCGAKYTSLDSFQTHL 653
G + ++ + Q G AP RP C +C K+ S + ++H+
Sbjct: 1090 GLCAGCMARSANG----------QVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHM 1139
Query: 654 KTHLDTVLPKLT------------------CPQCNKEFPNQESLLKHVTIHFMITSTYYI 695
+ + P+ + C +C F N+ + HV H + +
Sbjct: 1140 QVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHE 1199
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFV----FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKV 751
C+ C++ F S L HL++ H+F F+C +C VF +Q H+ H E K+
Sbjct: 1200 CKLCNQMFDSPAKLLCHLIE-HSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKI 1258
Query: 752 YRCTSCNWDFRNETDLQLHVKHNHLE 777
Y C+ C F +T+LQ H H +
Sbjct: 1259 YDCSQCPQKFFFQTELQNHTMSQHAQ 1284
Score = 118 bits (295), Expect = 4e-26
Identities = 149/676 (22%), Positives = 250/676 (36%), Gaps = 118/676 (17%)
Query: 690 TSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEK 749
T Y C+ CDK F + L++H + F+CT C +F K S H+ + H+ +K
Sbjct: 134 TGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKL-HTGDK 192
Query: 750 KVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKK- 808
K Y C C F L++H+K + + K KC C F + LQ H+ H K
Sbjct: 193 K-YHCHECEAAFSRSDHLKIHLKTH---SSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNK 248
Query: 809 --------------YNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKE 854
+ C +C F LEKH+ +H P + +
Sbjct: 249 EHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRH-------PQLSEKADLQCIHCP 301
Query: 855 EV--ELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYT----METLLQNHQLRD 908
EV + TLL + ++H + + C +C ++ + L +H+ D
Sbjct: 302 EVFVDENTLLAHIHQAH------------ANQKHKCPMCPEQFSSVEGVYCHLDSHRQPD 349
Query: 909 ---HNIRPG---------ESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPV 956
H++ P SA A + +G+ + + + +R+ Q V
Sbjct: 350 SSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTL-KPLRGQKKMRDDGQGWTKVV 408
Query: 957 KHYMCPICGER-FPSLLTLTEH-KVTHS-KSLDTGNCRICKMPLQSEEEFLEHCQM---- 1009
Y CP C +R F SL L H K H+ K + C+IC + + EH +
Sbjct: 409 --YSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKN 466
Query: 1010 --HPDLR-NSLTGFRCVVCMQTVTSTLELKIH-GTFHMQKTGNGSAVQTTGRGQHVQKLY 1065
+P ++ +++ F C C + L+ H H N S +
Sbjct: 467 HAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNA---------F 517
Query: 1066 KCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGI----------NVPPGTNR 1115
C C F ++ L + + C+ V +K SP + + P TN
Sbjct: 518 FCNQCSMGFLTESSLTE----HIQQAHCS--VGSAKLESPVVQPTQSFMEVYSCPYCTNS 571
Query: 1116 PGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKT 1175
P G L+ ++K ++ H + E P S+ ++ +
Sbjct: 572 PIFGSILKLTK-----------------HIKENHKNIPLAHSKKSKAEQSPVSSDVEVSS 614
Query: 1176 PQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFD 1235
P+ + + S S+ + Y C +C + F N Q H+ H+ C C + FD
Sbjct: 615 PKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFD 672
Query: 1236 SPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKF 1295
S L HL H + + C C F + LQ+H+ H +Y CT C + F
Sbjct: 673 SQESLLQHLTVH-YMTTSTHYVCESCDKQFSSVDDLQKHLLDMH--TFVLYHCTLCQEVF 729
Query: 1296 FFQTELQNHTMTQHSS 1311
+ +Q H +HS+
Sbjct: 730 DSKVSIQVHLAVKHSN 745
Score = 50.1 bits (118), Expect = 1e-05
Identities = 64/309 (20%), Positives = 99/309 (32%), Gaps = 71/309 (22%)
Query: 17 CKLEDKTEDGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGV 76
CK+ ++E+ C+ P+ L C C+Q S ++ H Q G
Sbjct: 993 CKMPLQSEEEFIEHCQMHPDLRNSLTG---FRCVVCMQTVTSTLELKIHGTFHMQKLAGS 1049
Query: 77 DVEDDPT---------CSWPASSPSSKDQTSPSHGEGCDFG-----------EEEGGPGL 116
P C+ SK G +G + GG
Sbjct: 1050 SAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMARSANGQVGGLAP 1109
Query: 117 PYP---------CQFCDKSFSRLSYLKHHEQ-SHSDKLP-------------------FK 147
P P C C F L+ H Q H D P ++
Sbjct: 1110 PEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQ 1169
Query: 148 CTYCSRLFKHKRSRDRHIKLHTGDK--KYHCSECDAAFSRSDHLKIHLKTHT---SNKPY 202
C C F+++R H+ H ++ + C C+ F L HL H+ +
Sbjct: 1170 CIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTF 1229
Query: 203 KCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQ 262
KC +C F+ ++ L H+ +D K+ D CSQC + F F +LQ
Sbjct: 1230 KCPVCFTVFVQANKLQQHIFAVHGQED-----------KIYD---CSQCPQKFFFQTELQ 1275
Query: 263 KHIAECHPE 271
H H +
Sbjct: 1276 NHTMSQHAQ 1284
>gi|118600985 zinc finger protein 91 [Homo sapiens]
Length = 1191
Score = 268 bits (684), Expect = 3e-71
Identities = 273/1135 (24%), Positives = 411/1135 (36%), Gaps = 221/1135 (19%)
Query: 49 CDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFG 108
C C + F S +T HK + ED P + T +H C
Sbjct: 212 CKECEKTFHWSSTLTNHK--------EIHTEDKPYKCEECGKAFKQLSTLTTHKIIC--A 261
Query: 109 EEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLH 168
+E+ Y C+ C K+F S L H++ H+ + P+KC C + F H + +H ++H
Sbjct: 262 KEK-----IYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIH 316
Query: 169 TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNK 228
TG+K Y C EC AFSRS L H + HT KPYKC C + F +SS+L H H K
Sbjct: 317 TGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEK 376
Query: 229 DGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHE 288
KC +C++ F L KH + +C C +
Sbjct: 377 ----------------PYKCKECDKAFKRLSTLTKHKI-------IHAGEKLYKCEECGK 413
Query: 289 LFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSL 346
F ++L H + +H+GEK C C ++F+ L H H ++P C
Sbjct: 414 AFNRSSNLTIH-KFIHTGEKPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKEC----- 467
Query: 347 VTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYS 406
+ SST+ +R ++ + P Y
Sbjct: 468 --------------GKAFIWSSTL---------TRHKRIHTGEKP-------------YK 491
Query: 407 CIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPG 466
C C K F + L H K +H E+ + + C + LN+H K +H + P
Sbjct: 492 CEECGK-AFRQSSTLTKH-KIIHTG--EKPYKFEECGKAFRQSLTLNKH-KIIHSREKP- 545
Query: 467 LIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDS 526
Y+C C + +TL H G + C C F S
Sbjct: 546 ----------YKCKECGKAFKQFSTLTTHKIIHAG--------KKLYKCEECGKAFNHSS 587
Query: 527 SLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHK 586
SL H + +H +G + Y C C + +++S L+ +K
Sbjct: 588 SLSTH-KIIH---TGEK---------------SYKCEECGKAFLWSSTLRRHKR------ 622
Query: 587 NIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYT 644
IH G+K ++L + + TGE Y C +CG ++
Sbjct: 623 --------IHTGEKPYKCEECGKAFSHSSALAKHKRI------HTGEKPYKCKECGKAFS 668
Query: 645 SLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFT 704
+ + H TH + K C +C+K F +L KH IH Y CE C K F
Sbjct: 669 NSSTLANHKITHTEEKPYK--CKECDKTFKRLSTLTKHKIIH--AGEKLYKCEECGKAFN 724
Query: 705 SVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNE 764
+L H ++C C + F+ S+ H + H+ EK ++C C F
Sbjct: 725 RSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRI-HTREKP-FKCKECGKAFIWS 782
Query: 765 TDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAII 822
+ L +H + K +KC CG++F L H T H+ K Y CK C KAF
Sbjct: 783 STL---TRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSS 839
Query: 823 LLEKHLREKHCVFETKTPNCGT--NGASEQVQKEEVELQTLLTNSQESHNSHDGS----- 875
L KH K CG N +S + + + + S+E + S
Sbjct: 840 ALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTE 899
Query: 876 EEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVC 935
+ + T E Y C+ CG A++ + L H+ +P YKC C
Sbjct: 900 HKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKP----------------YKCEEC 943
Query: 936 SRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKM 995
+ F + L H H G K Y C CG+ F TLTEHK+ H+ C C
Sbjct: 944 GKAFSQSSTLTTHKIIHTGE-KPYKCEECGKAFRKSSTLTEHKIIHTGE-KPYKCEECGK 1001
Query: 996 PLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFH-------MQKTGN 1048
H +MH + ++C C + + +L H H ++ G
Sbjct: 1002 AFSQSSTLTRHTRMHTGEK----PYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEECGK 1057
Query: 1049 GSAVQTTGRGQ---HV-QKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSK 1101
+T G H +K YKC C K F L +L PY C C K
Sbjct: 1058 AFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGEKPY-KCGECGKAFK 1116
Query: 1102 SASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNH 1156
+S L +++ + G +C C F S L NH
Sbjct: 1117 ESS------------ALTKHKII-------HTGEKPYKCEKCGKAFNQSSILTNH 1152
Score = 250 bits (639), Expect = 5e-66
Identities = 254/1045 (24%), Positives = 377/1045 (36%), Gaps = 218/1045 (20%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F S + +HK + + P S+ T H +
Sbjct: 291 EKPYKCEECGKAFSHSSTLAKHK--------RIHTGEKPYKCEECGKAFSRSSTLAKH-K 341
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C+ C K+FS S L +H+ +H+++ P+KC C + FK + +
Sbjct: 342 RIHTGEK------PYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFKRLSTLTK 395
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H +H G+K Y C EC AF+RS +L IH HT KPYKC C + F SSSL H +
Sbjct: 396 HKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRF 455
Query: 224 HERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQC 283
H R K KC +C + F + L +H H P +C
Sbjct: 456 HTREK----------------PFKCKECGKAFIWSSTLTRH-KRIHTGEKP------YKC 492
Query: 284 VYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSH--MDSHQQPESCNHS 341
C + F + ++L H + +H+GEK C ++F L H + S ++P C
Sbjct: 493 EECGKAFRQSSTLTKH-KIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKEC 551
Query: 342 NSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQA 401
+ S+ T T
Sbjct: 552 GK------AFKQFSTLT-----------------------------------THKIIHAG 570
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
K Y C C K F+ + L H K +H E+++ C+ C + L H K++H
Sbjct: 571 KKLYKCEECGK-AFNHSSSLSTH-KIIHTG--EKSYKCEECGKAFLWSSTLRRH-KRIHT 625
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+C C + + + L +H R G + C C
Sbjct: 626 GEKP-----------YKCEECGKAFSHSSALAKHKRIHTG--------EKPYKCKECGKA 666
Query: 522 FLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
F S+L H + T ++P Y C C + F + L KH
Sbjct: 667 FSNSSTLANH---------------KITHTEEKP----YKCKECDKT--FKRLSTLTKH- 704
Query: 582 KENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQC 639
IH G+K ++L + + + TGE Y C +C
Sbjct: 705 -----------KIIHAGEKLYKCEECGKAFNRSSNLTIHKFI------HTGEKPYKCEEC 747
Query: 640 GAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESC 699
G + S H + H T C +C K F +L +H IH Y CE C
Sbjct: 748 GKAFNWSSSLTKHKRIH--TREKPFKCKECGKAFIWSSTLTRHKRIH--TGEKPYKCEEC 803
Query: 700 DKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNW 759
K F+ L KH ++C C + F ++ H + H+ E K+Y+C C
Sbjct: 804 GKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKII-HAGE-KLYKCEECGK 861
Query: 760 DFRNETDLQLHVKHNHLENQGKVHKC--IFCGESFGTEVELQCHITTHSKKYNCKFCSKA 817
F ++L H + E K +C F S TE + I T K Y C+ C KA
Sbjct: 862 AFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHK---RIHTREKTYKCEECGKA 918
Query: 818 FHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEE 877
F L H R K CG K + TL T+ +
Sbjct: 919 FSQPSHLTTHKRMHTGEKPYKCEECG---------KAFSQSSTLTTH------------K 957
Query: 878 DVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSR 937
+ T E Y C+ CG A+ + L H++ I GE YKC C +
Sbjct: 958 IIHTGEKPYKCEECGKAFRKSSTLTEHKI----IHTGEKP------------YKCEECGK 1001
Query: 938 TFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPL 997
F + L H + H G K Y C CG+ F LT HK+ H+ C C
Sbjct: 1002 AFSQSSTLTRHTRMHTGE-KPYKCEECGKAFNRSSKLTTHKIIHTGE-KPYKCEECGKAF 1059
Query: 998 QSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGR 1057
S H ++H + ++C C + + + L H H TG
Sbjct: 1060 ISSSTLNGHKRIHTREK----PYKCEECGKAFSQSSTLTRHKRLH---TG---------- 1102
Query: 1058 GQHVQKLYKCASCLKEFRSKQDLVK 1082
+K YKC C K F+ L K
Sbjct: 1103 ----EKPYKCGECGKAFKESSALTK 1123
Score = 250 bits (638), Expect = 7e-66
Identities = 240/1015 (23%), Positives = 373/1015 (36%), Gaps = 166/1015 (16%)
Query: 43 DEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHG 102
++ + C+ C + F+ LS +T HKI + E W ++ K +
Sbjct: 234 EDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHT---- 289
Query: 103 EGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRD 162
GE+ PY C+ C K+FS S L H++ H+ + P+KC C + F +
Sbjct: 290 -----GEK------PYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFSRSSTLA 338
Query: 163 RHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQ 222
+H ++HTG+K Y C EC AFS S L H THT KPYKC C + F S+L H
Sbjct: 339 KHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFKRLSTLTKHKI 398
Query: 223 VHERNK--------DGSQSGSRMEDWKMKDT----QKCSQCEEGFDFPEDLQKHIAECHP 270
+H K S + K T KC +C + F++ L KH H
Sbjct: 399 IHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKH-KRFHT 457
Query: 271 ECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMD 330
P +C C + F+ ++L H +++H+GEK C C ++F L H
Sbjct: 458 REKP------FKCKECGKAFIWSSTLTRH-KRIHTGEKPYKCEECGKAFRQSSTLTKHKI 510
Query: 331 SH--QQP---ESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKR 385
H ++P E C + SL +++ ++ + K + +
Sbjct: 511 IHTGEKPYKFEECGKAFRQSL-----------------TLNKHKIIHSREKPYKCKECGK 553
Query: 386 AAQQTPDMTGPSSKQA-KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLE 444
A +Q +T A K Y C C K F+ + L H K +H E+++ C+ C +
Sbjct: 554 AFKQFSTLTTHKIIHAGKKLYKCEECGKA-FNHSSSLSTH-KIIHTG--EKSYKCEECGK 609
Query: 445 VLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFAN 504
L H K++H + P Y+C C + + + L +H R G
Sbjct: 610 AFLWSSTLRRH-KRIHTGEKP-----------YKCEECGKAFSHSSALAKHKRIHTG--- 654
Query: 505 PAAKDSNAFFCPHCYMGFLTDSSLEEH---------IRQVHCDLSGSRFGSPVLGTPKEP 555
+ C C F S+L H + CD + R +
Sbjct: 655 -----EKPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHA 709
Query: 556 VVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQT 615
++Y C C + FN L H +IH G+K +
Sbjct: 710 GEKLYKCEECGKA--FNRSSNLTIH------------KFIHTGEKPYKCEECGKAFNWSS 755
Query: 616 SLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPN 675
SL + + +P + C +CG + + H + H T C +C K F
Sbjct: 756 SLTKHKRIH-TREKP---FKCKECGKAFIWSSTLTRHKRIH--TGEKPYKCEECGKAFSR 809
Query: 676 QESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKV 735
+L KH TIH Y C+ C K F L KH + ++C C + F+
Sbjct: 810 SSTLTKHKTIH--TGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSS 867
Query: 736 SIQLHLAVKHSNEK---------------------------KVYRCTSCNWDFRNETDLQ 768
++ H + H+ EK K Y+C C F + L
Sbjct: 868 NLTTHKII-HTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHL- 925
Query: 769 LHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEK 826
H + K +KC CG++F L H I T K Y C+ C KAF L +
Sbjct: 926 --TTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTE 983
Query: 827 HLREKHCVFETKTPNCGTNGASEQVQKEEVELQT-------LLTNSQESHNSHDGSEEDV 879
H K CG + + T + +S + + +
Sbjct: 984 HKIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKII 1043
Query: 880 DTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRP----------GESAIVKKKAELIKGN 929
T E Y C+ CG A+ + L H+ +P +S+ + + L G
Sbjct: 1044 HTGEKPYKCEECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGE 1103
Query: 930 --YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHS 982
YKC C + F + L +H H G K Y C CG+ F LT HK H+
Sbjct: 1104 KPYKCGECGKAFKESSALTKHKIIHTGE-KPYKCEKCGKAFNQSSILTNHKKIHT 1157
Score = 243 bits (620), Expect = 9e-64
Identities = 280/1191 (23%), Positives = 429/1191 (36%), Gaps = 224/1191 (18%)
Query: 146 FKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCA 205
F+C ++F + +RH HTG K + C +C +F H H + + K KC
Sbjct: 154 FQCGKYLKVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCK 213
Query: 206 ICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHI 265
C + F SS+L H ++H +K KC +C + F L H
Sbjct: 214 ECEKTFHWSSTLTNHKEIHTEDK----------------PYKCEECGKAFKQLSTLTTHK 257
Query: 266 AECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEEL 325
C E +C C + F+ ++L H +++H+GEK C C ++F L
Sbjct: 258 IICAKE-------KIYKCEECGKAFLWSSTLTRH-KRIHTGEKPYKCEECGKAFSHSSTL 309
Query: 326 YSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGR 383
H H ++P C + + S L+ P K G+
Sbjct: 310 AKHKRIHTGEKPYKCEECG------------KAFSRSSTLAKHKRIHTGEKPYKCKECGK 357
Query: 384 KRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCL 443
+ T + + K Y C C+K F L+ L H K +H E+ + C+ C
Sbjct: 358 AFSNSSTLANHKITHTEEK-PYKCKECDK-AFKRLSTLTKH-KIIHAG--EKLYKCEECG 412
Query: 444 EVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFA 503
+ NL H K +H + P Y+C C + N ++L +H R H
Sbjct: 413 KAFNRSSNLTIH-KFIHTGEKP-----------YKCEECGKAFNWSSSLTKHKR-FHTRE 459
Query: 504 NPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFGS-------PVL 549
P F C C F+ S+L H +++H C+ G F ++
Sbjct: 460 KP-------FKCKECGKAFIWSSTLTRH-KRIHTGEKPYKCEECGKAFRQSSTLTKHKII 511
Query: 550 GTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSP 609
T ++P Y C + F L LNKH + + P GK + S L+
Sbjct: 512 HTGEKP----YKFEECGKA--FRQSLTLNKHKIIHSREKPYKCK--ECGKAFKQFSTLTT 563
Query: 610 VAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQC 669
I K+ Y C +CG + S TH H T C +C
Sbjct: 564 HKIIHAGKKL--------------YKCEECGKAFNHSSSLSTHKIIH--TGEKSYKCEEC 607
Query: 670 NKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQE 729
K F +L +H IH Y CE C K F+ L KH ++C C +
Sbjct: 608 GKAFLWSSTLRRHKRIH--TGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGK 665
Query: 730 VFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCG 789
F + ++ H + H+ E+K Y+C C+ F+ + L KH + K++KC CG
Sbjct: 666 AFSNSSTLANH-KITHT-EEKPYKCKECDKTFKRLSTL---TKHKIIHAGEKLYKCEECG 720
Query: 790 ESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGA 847
++F L H I T K Y C+ C KAF+ L KH R K CG
Sbjct: 721 KAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECG---- 776
Query: 848 SEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLR 907
K + TL + + + T E Y C+ CG A++ + L H+
Sbjct: 777 -----KAFIWSSTLTRHKR------------IHTGEKPYKCEECGKAFSRSSTLTKHK-- 817
Query: 908 DHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGER 967
I GE YKC C + F + L +H H G K Y C CG+
Sbjct: 818 --TIHTGEKP------------YKCKECGKAFKHSSALAKHKIIHAGE-KLYKCEECGKA 862
Query: 968 FPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQ 1027
F LT HK+ H+K C EH ++H + ++C C +
Sbjct: 863 FNQSSNLTTHKIIHTKE-KPSKSEECDKAFIWSSTLTEHKRIHTREKT----YKCEECGK 917
Query: 1028 TVTSTLELKIHGTFH----------MQKTGNGSAVQTTGRGQHV-QKLYKCASCLKEFRS 1076
+ L H H K + S+ TT + H +K YKC C K FR
Sbjct: 918 AFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRK 977
Query: 1077 KQDLVK---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV 1133
L + + PY C K+ S + T +
Sbjct: 978 SSTLTEHKIIHTGEKPY----KCEECGKAFSQSSTLTRHT----------------RMHT 1017
Query: 1134 GGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKK 1193
G +C C F S+L H + IH +K
Sbjct: 1018 GEKPYKCEECGKAFNRSSKLTTH-KIIH----------------------------TGEK 1048
Query: 1194 TYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMG 1253
Y+C +C F + + H H ++ ++C+ C + F + L H H+ E
Sbjct: 1049 PYKCEECGKAFISSSTLNGHKRIHTREK--PYKCEECGKAFSQSSTLTRHKRLHTGE--- 1103
Query: 1254 GTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+KC C F +++ L +H G +K Y C +C + F + L NH
Sbjct: 1104 KPYKCGECGKAFKESSALTKHKIIHTG--EKPYKCEKCGKAFNQSSILTNH 1152
Score = 194 bits (492), Expect = 6e-49
Identities = 219/935 (23%), Positives = 348/935 (37%), Gaps = 138/935 (14%)
Query: 407 CIYCNKQLFSSLAVLQIHLKTMH--LDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
C C K + S +++H KT H + E++ C+ C + L H K++H
Sbjct: 181 CFKCKKCVKSFC--IRLH-KTQHKCVYITEKSCKCKECEKTFHWSSTLTNH-KEIHTEDK 236
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEH-IRCSHGFANPAAKDSNAFFCPHCYMGFL 523
P Y+C C + L+TL H I C+ + C C FL
Sbjct: 237 P-----------YKCEECGKAFKQLSTLTTHKIICAK---------EKIYKCEECGKAFL 276
Query: 524 TDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKE 583
S+L H +++H T ++P Y C C + +S L +K I
Sbjct: 277 WSSTLTRH-KRIH--------------TGEKP----YKCEECGKAFSHSSTLAKHKRI-- 315
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGA 641
H G+K ++L + + TGE Y C +CG
Sbjct: 316 ------------HTGEKPYKCEECGKAFSRSSTLAKHKRIH------TGEKPYKCKECGK 357
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDK 701
+++ + H TH + K C +C+K F +L KH IH Y CE C K
Sbjct: 358 AFSNSSTLANHKITHTEEKPYK--CKECDKAFKRLSTLTKHKIIH--AGEKLYKCEECGK 413
Query: 702 QFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDF 761
F +L H ++C C + F+ S+ H H+ EK ++C C F
Sbjct: 414 AFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRF-HTREKP-FKCKECGKAF 471
Query: 762 RNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFH 819
+ L +H + K +KC CG++F L H I T K Y + C KAF
Sbjct: 472 IWSSTL---TRHKRIHTGEKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFR 528
Query: 820 AIILLEKH--LREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQE-----SHNSH 872
+ L KH + + ++ K S + + L +E +H+S
Sbjct: 529 QSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHSSS 588
Query: 873 DGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKC 932
+ + + T E Y C+ CG A+ + L+ H+ I GE YKC
Sbjct: 589 LSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHK----RIHTGEKP------------YKC 632
Query: 933 NVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRI 992
C + F + L +H + H G K Y C CG+ F + TL HK+TH++ C+
Sbjct: 633 EECGKAFSHSSALAKHKRIHTGE-KPYKCKECGKAFSNSSTLANHKITHTEEKPY-KCKE 690
Query: 993 CKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQ-------- 1044
C + +H +H + ++C C + + L IH H
Sbjct: 691 CDKTFKRLSTLTKHKIIHAGEKL----YKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEE 746
Query: 1045 --KTGNGSAVQTTGRGQHV-QKLYKCASCLKEFRSKQDLVK---LDINGLPYGL--CAGC 1096
K N S+ T + H +K +KC C K F L + + PY C
Sbjct: 747 CGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKA 806
Query: 1097 VNLSKSASPGINVPPGTNR---PGLGQNENLSAIEGKGKV---GGLKTRCSSCNVKFESE 1150
+ S + + + G G+ S+ K K+ G +C C F
Sbjct: 807 FSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQS 866
Query: 1151 SELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDI 1210
S L H + IH + P + K S +KTY+C +C F +
Sbjct: 867 SNLTTH-KIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHL 925
Query: 1211 QVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANK 1270
H H ++ ++C+ C + F + L H I H+ E +KC C F +++
Sbjct: 926 TTHKRMHTGEKP--YKCEECGKAFSQSSTLTTHKIIHTGEK---PYKCEECGKAFRKSST 980
Query: 1271 LQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHT 1305
L +H G+ K Y C +C + F + L HT
Sbjct: 981 LTEHKIIHTGE--KPYKCEECGKAFSQSSTLTRHT 1013
Score = 120 bits (301), Expect = 9e-27
Identities = 144/619 (23%), Positives = 214/619 (34%), Gaps = 130/619 (21%)
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCT 755
C+ C K F +H T +C C++ F ++ H + E K Y+C
Sbjct: 184 CKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFHWSSTLTNHKEIH--TEDKPYKCE 241
Query: 756 SCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKF 813
C F+ + L H + + K++KC CG++F L H I T K Y C+
Sbjct: 242 ECGKAFKQLSTL---TTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEE 298
Query: 814 CSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHD 873
C KAF L KH R K CG S +S
Sbjct: 299 CGKAFSHSSTLAKHKRIHTGEKPYKCEECG---------------------KAFSRSSTL 337
Query: 874 GSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCN 933
+ + T E Y C CG A++ + L NH++ +P YKC
Sbjct: 338 AKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKP----------------YKCK 381
Query: 934 VCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRIC 993
C + F + L +H H G K Y C CG+ F LT HK H+ C C
Sbjct: 382 ECDKAFKRLSTLTKHKIIHAGE-KLYKCEECGKAFNRSSNLTIHKFIHTGEKPY-KCEEC 439
Query: 994 KMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQ 1053
+H + H + F+C C + + L H H
Sbjct: 440 GKAFNWSSSLTKHKRFHTREKP----FKCKECGKAFIWSSTLTRHKRIH----------- 484
Query: 1054 TTGRGQHVQKLYKCASCLKEFRSKQDLVKLDI---NGLPYGL--CAGCVNLSKSASPGIN 1108
TG +K YKC C K FR L K I PY C S +
Sbjct: 485 -TG-----EKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLT------ 532
Query: 1109 VPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDS 1168
L +++ + + E K C C F+ S L H + IH
Sbjct: 533 ---------LNKHKIIHSREKPYK-------CKECGKAFKQFSTLTTH-KIIHAG----- 570
Query: 1169 NSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECK 1228
KK Y+C +C F + + H H ++ +++C+
Sbjct: 571 -----------------------KKLYKCEECGKAFNHSSSLSTHKIIHTGEK--SYKCE 605
Query: 1229 LCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDC 1288
C + F + L+ H H+ E +KC C F ++ L +H G+ K Y C
Sbjct: 606 ECGKAFLWSSTLRRHKRIHTGEK---PYKCEECGKAFSHSSALAKHKRIHTGE--KPYKC 660
Query: 1289 TQCPQKFFFQTELQNHTMT 1307
+C + F + L NH +T
Sbjct: 661 KECGKAFSNSSTLANHKIT 679
Score = 94.4 bits (233), Expect = 7e-19
Identities = 120/556 (21%), Positives = 195/556 (35%), Gaps = 101/556 (18%)
Query: 799 QCHITTHSKKYNCKFCSKAFHAIILLEKH--------------LREKHCVFETKTPNCGT 844
QC T SK + C K F+ + +H + C+ KT +
Sbjct: 144 QCLTTAQSKVFQCGKYLKVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCV 203
Query: 845 NGASEQVQKEEVE----LQTLLTNSQESHN-----------------SHDGSEEDVDTSE 883
+ + +E E + LTN +E H S + + + E
Sbjct: 204 YITEKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKE 263
Query: 884 PMYGCDICGAAYTMETLLQNHQLRDHNIRP----------GESAIVKKKAELIKGN--YK 931
+Y C+ CG A+ + L H+ +P S+ + K + G YK
Sbjct: 264 KIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPYK 323
Query: 932 CNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCR 991
C C + F + L +H + H G K Y C CG+ F + TL HK+TH++ C+
Sbjct: 324 CEECGKAFSRSSTLAKHKRIHTGE-KPYKCKECGKAFSNSSTLANHKITHTEE-KPYKCK 381
Query: 992 ICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSA 1051
C + +H +H + ++C C + + L IH H TG
Sbjct: 382 ECDKAFKRLSTLTKHKIIHAGEKL----YKCEECGKAFNRSSNLTIHKFIH---TG---- 430
Query: 1052 VQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPGIN 1108
+K YKC C K F L K P+ C C +S
Sbjct: 431 ----------EKPYKCEECGKAFNWSSSLTKHKRFHTREKPF-KCKECGKAFIWSST--- 476
Query: 1109 VPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDS 1168
L +++ + G +C C F S L H + IH P
Sbjct: 477 ---------LTRHKRI-------HTGEKPYKCEECGKAFRQSSTLTKH-KIIHTGEKPYK 519
Query: 1169 NSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECK 1228
K + S +K Y+C +C F + H H + ++C+
Sbjct: 520 FEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAGKK--LYKCE 577
Query: 1229 LCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDC 1288
C + F+ + L H I H+ E ++KC C F+ ++ L++H G +K Y C
Sbjct: 578 ECGKAFNHSSSLSTHKIIHTGE---KSYKCEECGKAFLWSSTLRRHKRIHTG--EKPYKC 632
Query: 1289 TQCPQKFFFQTELQNH 1304
+C + F + L H
Sbjct: 633 EECGKAFSHSSALAKH 648
Score = 48.5 bits (114), Expect = 4e-05
Identities = 63/306 (20%), Positives = 107/306 (34%), Gaps = 65/306 (21%)
Query: 1004 LEHCQMHPDLRNSLTGFRCVVCMQTVTSTLEL--KIHGTFHMQKTGNGSAVQTTGRGQHV 1061
++ C++H + N L C+ T S + K F+ N ++ TG+
Sbjct: 129 VDECKVHKEGYNKLNQ-----CLTTAQSKVFQCGKYLKVFYKFLNSNRHTIRHTGK---- 179
Query: 1062 QKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQN 1121
K +KC C+K F C+ L K+ + + +
Sbjct: 180 -KCFKCKKCVKSF---------------------CIRLHKTQHKCVYITEKS-------- 209
Query: 1122 ENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPM 1181
+C C F S L NH + IH E P K +
Sbjct: 210 ----------------CKCKECEKTFHWSSTLTNH-KEIHTEDKPYKCEECGKAFKQLST 252
Query: 1182 PRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQ 1241
++K Y+C +C F + H H ++ ++C+ C + F + L
Sbjct: 253 LTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGEKP--YKCEECGKAFSHSSTLA 310
Query: 1242 CHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTEL 1301
H H+ E +KC C F +++ L +H G+ K Y C +C + F + L
Sbjct: 311 KHKRIHTGEK---PYKCEECGKAFSRSSTLAKHKRIHTGE--KPYKCKECGKAFSNSSTL 365
Query: 1302 QNHTMT 1307
NH +T
Sbjct: 366 ANHKIT 371
>gi|6005976 zinc finger protein 208 [Homo sapiens]
Length = 1167
Score = 260 bits (664), Expect = 7e-69
Identities = 254/1020 (24%), Positives = 393/1020 (38%), Gaps = 163/1020 (15%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F + +T+HKI + + P SK T +H +
Sbjct: 254 EKSYKCEECGKAFNQSAILTKHKI--------IHTGEKPNKCEECGKAFSKVSTLTTH-K 304
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C+ C K+FS++S L H+ H+ + P+KC C + F +
Sbjct: 305 AIHAGEK------PYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTK 358
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H +HTG+K Y C EC A+ L H K HT KPYKC C +GF S L H +
Sbjct: 359 HKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVI 418
Query: 224 H---------ERNKDGSQSGSRMEDWKMKDTQ---KCSQCEEGFDFPEDLQKHIAECHPE 271
H E K + S + ME K+ + KC +C +GF + L H + H
Sbjct: 419 HTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYH-KKIHTV 477
Query: 272 CSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDS 331
P +C C + F + L+ H +++H+GEK C C ++F V L +H
Sbjct: 478 EKP------YKCEECGKAFNQSAILIKH-KRIHTGEKPYKCEECGKTFSKVSTLTTHKAI 530
Query: 332 H--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQ 389
H ++P C G T + +T ++ ++ + G K
Sbjct: 531 HAGEKPYKCKEC--------GKTFIKVSTLTTHKAIHA--------------GEK----- 563
Query: 390 TPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSL 449
Y C C K FS ++L H K +H E+ + C+ C +
Sbjct: 564 --------------PYKCKECGKA-FSKFSILTKH-KVIHTG--EKPYKCEECGKAFNWS 605
Query: 450 YNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKD 509
NL EH K++H + P Y+C C + + + L +H + H P
Sbjct: 606 SNLMEH-KRIHTGEKP-----------YKCEECGKSFSTFSVLTKH-KVIHTGEKP---- 648
Query: 510 SNAFFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFGSPVLGTPKEPV---VEV 559
+ C C + S+L H +++H C+ G F + + + +
Sbjct: 649 ---YKCEECGKAYKWSSTLSYH-KKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKP 704
Query: 560 YSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKM 619
Y C C + F+ V L H IH G+K A + S+
Sbjct: 705 YKCEECGKT--FSKVSTLTTH------------KAIHAGEKPYKCKECGK-AFSKFSILT 749
Query: 620 MQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESL 679
V +P Y C +CG Y + H K H T C +C K F L
Sbjct: 750 KHKVIHTGEKP---YKCEECGKAYKWPSTLSYHKKIH--TGEKPYKCEECGKGFSMFSIL 804
Query: 680 LKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQL 739
KH IH Y CE C K F+ + KH F++C C + +++ +
Sbjct: 805 TKHEVIH--TGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTK 862
Query: 740 HLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQ 799
H + H+ EK Y+C C F ++L H K + E +KC C ++F L
Sbjct: 863 HKVI-HTGEKP-YKCEECGKAFNWSSNLMEHKKIHTGETP---YKCEECDKAFSWPSSLT 917
Query: 800 CHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGT--NGASEQVQKEE 855
H TH+ K Y C+ C KAF L +H K CG N +S ++ +
Sbjct: 918 EHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEHKR 977
Query: 856 VELQTLLTNSQESHNSHDG-----SEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHN 910
+ +E S + + T E Y C+ CG AY + L H+
Sbjct: 978 IHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTV 1037
Query: 911 IRPGES----------AIVKKKAELIKGN--YKCNVCSRTFFSENGLREHMQTHLGPVKH 958
+P + +I+ K + G YKC C + + + LR H + H G K
Sbjct: 1038 EKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGE-KP 1096
Query: 959 YMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLT 1018
Y C CG+ F + LT+HKV H+ C C F +H ++H + N T
Sbjct: 1097 YKCEECGKAFSTFSILTKHKVIHTGE-KPYKCEECGKAFSWLSVFSKHKKIHTGVPNPPT 1155
Score = 247 bits (631), Expect = 5e-65
Identities = 248/986 (25%), Positives = 368/986 (37%), Gaps = 165/986 (16%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C+ K+F+ S L +++ +H+ + P++C C + F +H +HTG+K Y C
Sbjct: 201 YKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKSYKCE 260
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
EC AF++S L H HT KP KC C + F S+L H +H K
Sbjct: 261 ECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAIHAGEK--------- 311
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
KC +C + F L H A H P +C C + F + + L
Sbjct: 312 -------PYKCKECGKAFSKVSTLITHKA-IHAGEKP------YKCKECGKAFSKFSILT 357
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
H + +H+GEK C C +++ L H H ++P C G++ S
Sbjct: 358 KH-KVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGK------GFSMFS 410
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLF 415
T + P K + M + Y C C K F
Sbjct: 411 ILTKHEVIHTGEK-------PYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKG-F 462
Query: 416 SSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAI 475
S + L H K ++KP + C+ C + L +H K++H + P
Sbjct: 463 SWSSTLSYHKKIHTVEKP---YKCEECGKAFNQSAILIKH-KRIHTGEKP---------- 508
Query: 476 VYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQV 535
Y+C C + + ++TL H + H P + C C F+ S+L H + +
Sbjct: 509 -YKCEECGKTFSKVSTLTTH-KAIHAGEKP-------YKCKECGKTFIKVSTLTTH-KAI 558
Query: 536 H----------CDLSGSRFG----SPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
H C + S+F V+ T ++P Y C C + ++S L +K I
Sbjct: 559 HAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKP----YKCEECGKAFNWSSNLMEHKRI 614
Query: 582 KENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGA 641
K GK S L+ + T K Y C +CG
Sbjct: 615 HTGEKPYKCE----ECGKSFSTFSVLTKHKVIHTGEK--------------PYKCEECGK 656
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDK 701
Y + H K H TV C +C K F L+KH IH Y CE C K
Sbjct: 657 AYKWSSTLSYHKKIH--TVEKPYKCEECGKAFNRSAILIKHKRIH--TDEKPYKCEECGK 712
Query: 702 QFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDF 761
F+ V L H ++C C + F SK SI V H+ EK Y+C C +
Sbjct: 713 TFSKVSTLTTHKAIHAGEKPYKCKECGKAF-SKFSILTKHKVIHTGEKP-YKCEECGKAY 770
Query: 762 RNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFH 819
+ + L H K + K +KC CG+ F L H I T K Y C+ C KAF
Sbjct: 771 KWPSTLSYHKK---IHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFS 827
Query: 820 AIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDV 879
+ + KH + K CG + ++LT + H
Sbjct: 828 WLSVFSKHKKTHAGEKFYKCEACG----------KAYNTFSILTKHKVIH---------- 867
Query: 880 DTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTF 939
T E Y C+ CG A+ + L H+ I GE+ YKC C + F
Sbjct: 868 -TGEKPYKCEECGKAFNWSSNLMEHK----KIHTGETP------------YKCEECDKAF 910
Query: 940 FSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQS 999
+ L EH TH G K Y C CG+ F LTEHK TH+ + C C
Sbjct: 911 SWPSSLTEHKATHAGE-KPYKCEECGKAFSWPSRLTEHKATHAGE-EPYKCEECGKAFNW 968
Query: 1000 EEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFH-------MQKTGN---- 1048
+EH ++H + ++C C ++ ++ L H H ++ G
Sbjct: 969 SSNLMEHKRIHTGEK----PYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKW 1024
Query: 1049 GSAVQTTGRGQHVQKLYKCASCLKEF 1074
S + + V+K YKC C K F
Sbjct: 1025 SSTLSYHKKIHTVEKPYKCEECGKGF 1050
Score = 243 bits (620), Expect = 9e-64
Identities = 281/1179 (23%), Positives = 411/1179 (34%), Gaps = 284/1179 (24%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C+ C K+FS+ S L H+ H+ + +KC C + F +H +HTG+K C
Sbjct: 228 PYRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNKC 287
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
EC AFS+ L H H KPYKC C + F S+L H +H K
Sbjct: 288 EECGKAFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKP------- 340
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
KC +C + F L KH H P +C C + + ++L
Sbjct: 341 ---------YKCKECGKAFSKFSILTKHKV-IHTGEKP------YKCEECGKAYKWPSTL 384
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSV 354
H +++H+GEK C C + F L H H ++P C
Sbjct: 385 SYH-KKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGK----------- 432
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
+ SNL +K +TP Y C C K
Sbjct: 433 -AFNWSSNLM----------------EHKKIHTGETP-------------YKCEECGKG- 461
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
FS + L H K ++KP + C+ C + L +H K++H + P
Sbjct: 462 FSWSSTLSYHKKIHTVEKPYK---CEECGKAFNQSAILIKH-KRIHTGEKP--------- 508
Query: 475 IVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQ 534
Y+C C + + ++TL H + H P + C C F+ S+L H +
Sbjct: 509 --YKCEECGKTFSKVSTLTTH-KAIHAGEKP-------YKCKECGKTFIKVSTLTTH-KA 557
Query: 535 VH----------CDLSGSRFG----SPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKH 580
+H C + S+F V+ T ++P Y C C + ++S L +K
Sbjct: 558 IHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKP----YKCEECGKAFNWSSNLMEHKR 613
Query: 581 IKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCG 640
I K GK S L+ + T K Y C +CG
Sbjct: 614 IHTGEKPYKCE----ECGKSFSTFSVLTKHKVIHTGEK--------------PYKCEECG 655
Query: 641 AKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCD 700
Y + H K H TV C +C K F L+KH IH Y CE C
Sbjct: 656 KAYKWSSTLSYHKKIH--TVEKPYKCEECGKAFNRSAILIKHKRIH--TDEKPYKCEECG 711
Query: 701 KQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWD 760
K F+ V L H ++C C + F SK SI V H+ EK Y+C C
Sbjct: 712 KTFSKVSTLTTHKAIHAGEKPYKCKECGKAF-SKFSILTKHKVIHTGEKP-YKCEECGKA 769
Query: 761 FRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAF 818
++ + L H K + K +KC CG+ F L H H+ K Y C+ C KAF
Sbjct: 770 YKWPSTLSYHKK---IHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAF 826
Query: 819 HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
+ + KH + K CG + ++LT + H
Sbjct: 827 SWLSVFSKHKKTHAGEKFYKCEACG----------KAYNTFSILTKHKVIH--------- 867
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRT 938
T E Y C+ CG A+ + L H+ I GE+ YKC C +
Sbjct: 868 --TGEKPYKCEECGKAFNWSSNLMEHK----KIHTGETP------------YKCEECDKA 909
Query: 939 FFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQ 998
F + L EH TH G K Y C CG+ F LTEHK TH+ + C C
Sbjct: 910 FSWPSSLTEHKATHAGE-KPYKCEECGKAFSWPSRLTEHKATHAGE-EPYKCEECGKAFN 967
Query: 999 SEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRG 1058
+EH ++H TG
Sbjct: 968 WSSNLMEHKRIH--------------------------------------------TG-- 981
Query: 1059 QHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNR 1115
+K YKC C K F + L K + PY C C K +S
Sbjct: 982 ---EKPYKCEECGKSFSTFSILTKHKVIHTGEKPY-KCEECGKAYKWSST---------- 1027
Query: 1116 PGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKT 1175
L ++ + +E K C C F S L H + IH
Sbjct: 1028 --LSYHKKIHTVEKPYK-------CEECGKGFVMFSILAKH-KVIH-------------- 1063
Query: 1176 PQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFD 1235
+K Y+C +C + ++ H H ++ ++C+ C + F
Sbjct: 1064 --------------TGEKLYKCEECGKAYKWPSTLRYHKKIHTGEK--PYKCEECGKAFS 1107
Query: 1236 SPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1274
+ + L H + H+ E +KC C F + +H
Sbjct: 1108 TFSILTKHKVIHTGE---KPYKCEECGKAFSWLSVFSKH 1143
Score = 240 bits (613), Expect = 6e-63
Identities = 275/1185 (23%), Positives = 430/1185 (36%), Gaps = 202/1185 (17%)
Query: 127 FSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRS 186
F + S H+ H+ K +C R F +H +++T + Y C E AF+ S
Sbjct: 154 FHKCSNSNRHKIRHTGKKHLQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWS 213
Query: 187 DHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQ 246
L + HT KPY+C C + F S L H +H K +
Sbjct: 214 STLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEK----------------SY 257
Query: 247 KCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSG 306
KC +C + F+ L KH H PN +C C + F + ++L H + +H+G
Sbjct: 258 KCEECGKAFNQSAILTKH-KIIHTGEKPN------KCEECGKAFSKVSTLTTH-KAIHAG 309
Query: 307 EKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLS 364
EK C C ++F V L +H H ++P C S S
Sbjct: 310 EKPYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAF---------------SKFS 354
Query: 365 VDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSK--QAKVTYSCIYCNKQLFSSLAVLQ 422
+ + V P A + P K + Y C C K FS ++L
Sbjct: 355 ILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKG-FSMFSILT 413
Query: 423 IHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFC 482
H + +H E+ + C+ C + NL EH K++H + P Y+C C
Sbjct: 414 KH-EVIHTG--EKPYKCEECGKAFNWSSNLMEH-KKIHTGETP-----------YKCEEC 458
Query: 483 SEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGS 542
+ + +TL H + H P + C C F + L +H +++H
Sbjct: 459 GKGFSWSSTLSYHKKI-HTVEKP-------YKCEECGKAFNQSAILIKH-KRIH------ 503
Query: 543 RFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSR 602
T ++P Y C C + F+ V L H IH G+K
Sbjct: 504 --------TGEKP----YKCEECGKT--FSKVSTLTTH------------KAIHAGEKPY 537
Query: 603 ALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLP 662
I+ ++L +A+ A +P Y C +CG ++ H H T
Sbjct: 538 KCKECGKTFIKVSTLTTHKAI-HAGEKP---YKCKECGKAFSKFSILTKHKVIH--TGEK 591
Query: 663 KLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFF 722
C +C K F +L++H IH Y CE C K F++ L KH + +
Sbjct: 592 PYKCEECGKAFNWSSNLMEHKRIH--TGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPY 649
Query: 723 RCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKV 782
+C C + + ++ H + H+ EK Y+C C F L +KH + K
Sbjct: 650 KCEECGKAYKWSSTLSYHKKI-HTVEKP-YKCEECGKAFNRSAIL---IKHKRIHTDEKP 704
Query: 783 HKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTP 840
+KC CG++F L H H+ K Y CK C KAF +L KH K
Sbjct: 705 YKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCE 764
Query: 841 NCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETL 900
CG + + + L+ ++ H T E Y C+ CG ++M ++
Sbjct: 765 ECG----------KAYKWPSTLSYHKKIH-----------TGEKPYKCEECGKGFSMFSI 803
Query: 901 LQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYM 960
L H++ I GE YKC C + F + +H +TH G K Y
Sbjct: 804 LTKHEV----IHTGEKP------------YKCEECGKAFSWLSVFSKHKKTHAGE-KFYK 846
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGF 1020
C CG+ + + LT+HKV H+ C C +EH ++H T +
Sbjct: 847 CEACGKAYNTFSILTKHKVIHTGE-KPYKCEECGKAFNWSSNLMEHKKIH----TGETPY 901
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDL 1080
+C C + + L H H +K YKC C K F L
Sbjct: 902 KCEECDKAFSWPSSLTEHKATHAG-----------------EKPYKCEECGKAFSWPSRL 944
Query: 1081 VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKT-R 1139
+ A+ P G N + + +E K G K +
Sbjct: 945 TE------------------HKATHAGEEPYKCEECGKAFNWSSNLMEHKRIHTGEKPYK 986
Query: 1140 CSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIK 1199
C C F + S L H + IH P K + S +K Y+C +
Sbjct: 987 CEECGKSFSTFSILTKH-KVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEE 1045
Query: 1200 CQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCP 1259
C F + H H ++ ++C+ C + + P+ L+ H H+ E +KC
Sbjct: 1046 CGKGFVMFSILAKHKVIHTGEK--LYKCEECGKAYKWPSTLRYHKKIHTGE---KPYKCE 1100
Query: 1260 VCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C F + L +H G +K Y C +C + F + + H
Sbjct: 1101 ECGKAFSTFSILTKHKVIHTG--EKPYKCEECGKAFSWLSVFSKH 1143
Score = 142 bits (358), Expect = 2e-33
Identities = 170/712 (23%), Positives = 252/712 (35%), Gaps = 112/712 (15%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y C + G + + + H T C +C K F L KH IH S
Sbjct: 201 YKCEEGGKAFNWSSTLTYYKSAH--TGEKPYRCKECGKAFSKFSILTKHKVIHTGEKS-- 256
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y CE C K F L KH + +C C + F ++ H A+ H+ EK Y+
Sbjct: 257 YKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAI-HAGEKP-YK 314
Query: 754 CTSCNWDFRNETDLQLH-------------------------VKHNHLENQGKVHKCIFC 788
C C F + L H KH + K +KC C
Sbjct: 315 CKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEEC 374
Query: 789 GESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGT-- 844
G+++ L H I T K Y C+ C K F +L KH K CG
Sbjct: 375 GKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAF 434
Query: 845 NGASEQVQKEEVELQTLLTNSQE-----SHNSHDGSEEDVDTSEPMYGCDICGAAYTMET 899
N +S ++ +++ +E S +S + + T E Y C+ CG A+
Sbjct: 435 NWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSA 494
Query: 900 LLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHY 959
+L H+ I GE YKC C +TF + L H H G K Y
Sbjct: 495 ILIKHK----RIHTGEKP------------YKCEECGKTFSKVSTLTTHKAIHAGE-KPY 537
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTG 1019
C CG+ F + TLT HK H+ C+ C +H +H +
Sbjct: 538 KCKECGKTFIKVSTLTTHKAIHAGE-KPYKCKECGKAFSKFSILTKHKVIHTGEK----P 592
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQD 1079
++C C + + L H H TG +K YKC C K F +
Sbjct: 593 YKCEECGKAFNWSSNLMEHKRIH---TG--------------EKPYKCEECGKSFSTFSV 635
Query: 1080 LVK---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGL 1136
L K + PY C C K +S L ++ + +E K
Sbjct: 636 LTKHKVIHTGEKPY-KCEECGKAYKWSST------------LSYHKKIHTVEKPYK---- 678
Query: 1137 KTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKT-PQVSPMPRISPSQSDEKKTY 1195
C C F + L H + IH + P KT +VS + + E K Y
Sbjct: 679 ---CEECGKAFNRSAILIKH-KRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGE-KPY 733
Query: 1196 QCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGT 1255
+C +C F + H H ++ ++C+ C + + P+ L H H+ E
Sbjct: 734 KCKECGKAFSKFSILTKHKVIHTGEK--PYKCEECGKAYKWPSTLSYHKKIHTGE---KP 788
Query: 1256 FKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMT 1307
+KC C F + L +H G +K Y C +C + F + + H T
Sbjct: 789 YKCEECGKGFSMFSILTKHEVIHTG--EKPYKCEECGKAFSWLSVFSKHKKT 838
Score = 133 bits (335), Expect = 1e-30
Identities = 125/504 (24%), Positives = 195/504 (38%), Gaps = 92/504 (18%)
Query: 43 DEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHG 102
DE + C+ C + F +S +T HK + + P SK H
Sbjct: 701 DEKPYKCEECGKTFSKVSTLTTHK--------AIHAGEKPYKCKECGKAFSKFSILTKH- 751
Query: 103 EGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRD 162
+ GE+ PY C+ C K++ S L +H++ H+ + P+KC C + F
Sbjct: 752 KVIHTGEK------PYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILT 805
Query: 163 RHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQ 222
+H +HTG+K Y C EC AFS H KTH K YKC C + + + S L H
Sbjct: 806 KHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTKHKV 865
Query: 223 VH---------ERNKDGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKHIA---- 266
+H E K + S + ME K+ + KC +C++ F +P L +H A
Sbjct: 866 IHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATHAG 925
Query: 267 ----ECHPECSP--------NEDRAA------LQCVYCHELFVEETSLMNHMEQVHSGEK 308
+C EC E +A +C C + F ++LM H +++H+GEK
Sbjct: 926 EKPYKCE-ECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEH-KRIHTGEK 983
Query: 309 KNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVD 366
C C +SF T L H H ++P C + S LS
Sbjct: 984 PYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECG------------KAYKWSSTLSYH 1031
Query: 367 SSTMVEAAPPIPKSRGR-----KRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVL 421
P + G+ A+ TG + Y C C K + + L
Sbjct: 1032 KKIHTVEKPYKCEECGKGFVMFSILAKHKVIHTG------EKLYKCEECGK-AYKWPSTL 1084
Query: 422 QIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNF 481
+ H K +KP + C+ C + + L +H K +H + P Y+C
Sbjct: 1085 RYHKKIHTGEKP---YKCEECGKAFSTFSILTKH-KVIHTGEKP-----------YKCEE 1129
Query: 482 CSEVVNDLNTLQEHIRCSHGFANP 505
C + + L+ +H + G NP
Sbjct: 1130 CGKAFSWLSVFSKHKKIHTGVPNP 1153
Score = 101 bits (252), Expect = 4e-21
Identities = 141/613 (23%), Positives = 216/613 (35%), Gaps = 101/613 (16%)
Query: 703 FTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRC----TSCN 758
+T+VD+ + H + T +VF + +SN K+ C
Sbjct: 117 YTNVDECKVHKEGYNKLNQSLTTTQSKVFQRGKYANVFHKCSNSNRHKIRHTGKKHLQCK 176
Query: 759 WDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSK 816
R+ L +H + + +KC G++F L + + H+ K Y CK C K
Sbjct: 177 EYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGK 236
Query: 817 AFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSE 876
AF +L KH K CG + +LT + H
Sbjct: 237 AFSKFSILTKHKVIHTGEKSYKCEECG----------KAFNQSAILTKHKIIH------- 279
Query: 877 EDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCS 936
T E C+ CG A++ + L H+ I GE YKC C
Sbjct: 280 ----TGEKPNKCEECGKAFSKVSTLTTHKA----IHAGEKP------------YKCKECG 319
Query: 937 RTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMP 996
+ F + L H H G K Y C CG+ F LT+HKV H+ C C
Sbjct: 320 KAFSKVSTLITHKAIHAGE-KPYKCKECGKAFSKFSILTKHKVIHTGE-KPYKCEECGKA 377
Query: 997 LQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTG 1056
+ H ++H + ++C C + + L H H TG
Sbjct: 378 YKWPSTLSYHKKIHTGEK----PYKCEECGKGFSMFSILTKHEVIH---TG--------- 421
Query: 1057 RGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGC-VNLSKSASPGINVPPG 1112
+K YKC C K F +L+ K+ PY C C S S++
Sbjct: 422 -----EKPYKCEECGKAFNWSSNLMEHKKIHTGETPY-KCEECGKGFSWSST-------- 467
Query: 1113 TNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQ 1172
L ++ + +E K C C F + L H + IH P
Sbjct: 468 -----LSYHKKIHTVEKPYK-------CEECGKAFNQSAILIKH-KRIHTGEKPYKCEEC 514
Query: 1173 LKT-PQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCS 1231
KT +VS + + E K Y+C +C F + H A H ++ ++CK C
Sbjct: 515 GKTFSKVSTLTTHKAIHAGE-KPYKCKECGKTFIKVSTLTTHKAIHAGEK--PYKCKECG 571
Query: 1232 QTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQC 1291
+ F + L H + H+ E +KC C F ++ L +H G +K Y C +C
Sbjct: 572 KAFSKFSILTKHKVIHTGE---KPYKCEECGKAFNWSSNLMEHKRIHTG--EKPYKCEEC 626
Query: 1292 PQKFFFQTELQNH 1304
+ F + L H
Sbjct: 627 GKSFSTFSVLTKH 639
Score = 69.7 bits (169), Expect = 2e-11
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 34/190 (17%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F + S +T+HK+ E W ++ K +
Sbjct: 982 EKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPY 1041
Query: 104 GCDFGEEEGGPGLP-----------------YPCQFCDKSFSRLSYLKHHEQSHSDKLPF 146
C EE G G Y C+ C K++ S L++H++ H+ + P+
Sbjct: 1042 KC----EECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPY 1097
Query: 147 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFS----RSDHLKIHL--------- 193
KC C + F +H +HTG+K Y C EC AFS S H KIH
Sbjct: 1098 KCEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIHTGVPNPPTHK 1157
Query: 194 KTHTSNKPYK 203
K H K YK
Sbjct: 1158 KIHAGEKLYK 1167
>gi|122937213 zinc finger protein 99 [Homo sapiens]
Length = 1036
Score = 251 bits (640), Expect = 4e-66
Identities = 238/970 (24%), Positives = 360/970 (37%), Gaps = 175/970 (18%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C+ C K+F + S+L H+ H+ + P+KC C + F H + +H +HTG K Y C
Sbjct: 193 PYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKC 252
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
EC AFS+S L+ H HT KPYK C + F + S+L H +H K
Sbjct: 253 EECGKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHTGQK-------- 304
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
KC +C + F + L H H P +C C + F ++L
Sbjct: 305 --------PYKCEECGKAFKWSSKLTVH-KVIHTAEKP------CKCEECGKAFKRFSAL 349
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSV 354
H + +H+G++ C CS++F L H H ++P C
Sbjct: 350 RKH-KIIHTGKQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEECG------------ 396
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
+ S L+V +E P + G K + K Y C C K
Sbjct: 397 KAFKWSSKLTVHKVIHMEEKPCKCEECG-KAFKHFSALRKHKIIHTGKKPYKCEECGK-A 454
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
F++ + L H K +H K + + C+ C + +L H K +H + P
Sbjct: 455 FNNSSTLMKH-KIIHTGK--KPYKCEECGKAFKQSSHLTRH-KAIHTGEKP--------- 501
Query: 475 IVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEH--- 531
Y+C C + N + L++H + H P + C C F S+L +H
Sbjct: 502 --YKCEECGKAFNHFSALRKH-QIIHTGKKP-------YKCEECGKAFSQSSTLRKHEII 551
Query: 532 ---IRQVHCDLSGSRF-------GSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
+ C+ G F V+ T ++P Y C C + FN L KH
Sbjct: 552 HTGEKPYKCEECGKAFKWSSHLTRHKVIHTEEKP----YKCEECGKA--FNHFSALRKH- 604
Query: 582 KENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQC 639
IH GKK + ++L+ + + TGE Y C +C
Sbjct: 605 -----------KIIHTGKKPYKCEECGKAFSQSSTLRKHEII------HTGEKPYKCEEC 647
Query: 640 GAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESC 699
G + H H T C +C K F + +L KH IH Y CE C
Sbjct: 648 GKAFKWSSKLTVHKVIH--TAEKPCKCEECGKAFKHFSALRKHKIIH--TGKKPYKCEEC 703
Query: 700 DKQFTSVDDLQKH---------------LLDMHTFVF-----FRCTLCQEVFDSKVSIQL 739
K F + L+KH L H + ++C C + F++ +++
Sbjct: 704 GKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLRK 763
Query: 740 HLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQ 799
H + KK Y+C C F+ + L +H + K +KC CG++F L+
Sbjct: 764 HKII--YTGKKPYKCEECGKAFKQSSHL---TRHKAVHTGEKPYKCGECGKAFNNSSTLK 818
Query: 800 CH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVE 857
H I T K Y C+ C KAF L KH K + G + + EE E
Sbjct: 819 KHKLIHTREKSYKCEECGKAFSNFSALRKH----------KIIHTG----EKPYKCEECE 864
Query: 858 LQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESA 917
NS S + + T E Y C+ CG + + L H++ I GE
Sbjct: 865 CGKAFNNS-----STLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKI----IHTGEKP 915
Query: 918 IVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEH 977
YKC C + F + L +H H G K Y C G+ F LT+H
Sbjct: 916 ------------YKCEECGKAFKQSSHLTKHKSIHTGE-KPYKCEERGKAFSHFSRLTKH 962
Query: 978 KVTHSKSLDTGNCRICKMPLQSEE-----EFLEHCQMHPDLRNSLTGFRCVVCMQTVTST 1032
++ H+ C C+ P + EE H H + ++C C +
Sbjct: 963 RIIHT-GKKPYKCEECEKPYKCEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHL 1021
Query: 1033 LELKIHGTFH 1042
L H H
Sbjct: 1022 SALTKHKIIH 1031
Score = 207 bits (526), Expect = 7e-53
Identities = 196/801 (24%), Positives = 299/801 (37%), Gaps = 131/801 (16%)
Query: 49 CDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFG 108
C+ C + F+ S + +HKI + G CS S+ S+ + H G
Sbjct: 336 CEECGKAFKRFSALRKHKI----IHTGKQPYKCEECSKAFSNFSALRKHEIIH-----TG 386
Query: 109 EEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLH 168
E+ PY C+ C K+F S L H+ H ++ P KC C + FKH + +H +H
Sbjct: 387 EK------PYKCEECGKAFKWSSKLTVHKVIHMEEKPCKCEECGKAFKHFSALRKHKIIH 440
Query: 169 TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNK 228
TG K Y C EC AF+ S L H HT KPYKC C + F SS L H +H K
Sbjct: 441 TGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEK 500
Query: 229 DGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHE 288
KC +C + F+ L+KH H P +C C +
Sbjct: 501 ----------------PYKCEECGKAFNHFSALRKH-QIIHTGKKP------YKCEECGK 537
Query: 289 LFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSL 346
F + ++L H E +H+GEK C C ++F L H H ++P C
Sbjct: 538 AFSQSSTLRKH-EIIHTGEKPYKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECGK--- 593
Query: 347 VTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYS 406
+ S+ + P K +Q + + Y
Sbjct: 594 ---AFNHFSALRKHKIIHTGKK-------PYKCEECGKAFSQSSTLRKHEIIHTGEKPYK 643
Query: 407 CIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPG 466
C C K F + L +H +KP + C+ C + L +H K +H + P
Sbjct: 644 CEECGK-AFKWSSKLTVHKVIHTAEKPCK---CEECGKAFKHFSALRKH-KIIHTGKKP- 697
Query: 467 LIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKD------------SNAFF 514
Y+C C + N+ +TL++H G + ++ +
Sbjct: 698 ----------YKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPYK 747
Query: 515 CPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSV 574
C C F S+L +H ++ T K+P Y C C
Sbjct: 748 CEECGKAFNNSSTLRKH---------------KIIYTGKKP----YKCEEC------GKA 782
Query: 575 LKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEY 634
K + H+ HK +H G+K ++LK + + Y
Sbjct: 783 FKQSSHL-TRHK-------AVHTGEKPYKCGECGKAFNNSSTLKKHKLIHTREK----SY 830
Query: 635 ICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYY 694
C +CG +++ + + H H K +C K F N +L+KH IH Y
Sbjct: 831 KCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIH--TGEKPY 888
Query: 695 ICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRC 754
CE C K F + L KH + ++C C + F + H ++ H+ EK Y+C
Sbjct: 889 KCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSSHLTKHKSI-HTGEKP-YKC 946
Query: 755 TSCNWDFRNETDLQLH------VKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS-- 806
F + + L H K E K +KC CG++F L H T H+
Sbjct: 947 EERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGKAFNQSSHLTQHKTIHTGG 1006
Query: 807 KKYNCKFCSKAFHAIILLEKH 827
K Y C+ C KAF+ + L KH
Sbjct: 1007 KTYKCEECGKAFNHLSALTKH 1027
Score = 188 bits (477), Expect = 3e-47
Identities = 252/1121 (22%), Positives = 390/1121 (34%), Gaps = 245/1121 (21%)
Query: 151 CSRLFKHKRSRDRHIKLH-----TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCA 205
C + + K + + KL+ T K + C++ F + + + HT KPYKC
Sbjct: 138 CESVNEGKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCE 197
Query: 206 ICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHI 265
C + F SS L H +H K KC +C + F+ L+KH
Sbjct: 198 ECGKAFKQSSHLTRHKAIHTGEK----------------PYKCEECGKAFNHFSALRKH- 240
Query: 266 AECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEEL 325
H P +C C + F + ++L H E +H+ EK C ++F + L
Sbjct: 241 QIIHTGKKP------YKCEECGKAFSQSSTLRKH-EIIHTEEKPYKYEECGKAFSNLSAL 293
Query: 326 YSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGR 383
H H Q+P C + S L+V P
Sbjct: 294 RKHEIIHTGQKPYKCEECG------------KAFKWSSKLTVHKVIHTAEKP-------- 333
Query: 384 KRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCL 443
C C K F + L+ H K +H K Q + C+ C
Sbjct: 334 ---------------------CKCEECGK-AFKRFSALRKH-KIIHTGK--QPYKCEECS 368
Query: 444 EVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFA 503
+ + L +H + +H + P Y+C C + + L H + H
Sbjct: 369 KAFSNFSALRKH-EIIHTGEKP-----------YKCEECGKAFKWSSKLTVH-KVIHMEE 415
Query: 504 NPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCS 563
P C C F S+L +H ++ T K+P Y C
Sbjct: 416 KPCK-------CEECGKAFKHFSALRKH---------------KIIHTGKKP----YKCE 449
Query: 564 YCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAV 623
C + FN+ L KH IH GKK + + L +A+
Sbjct: 450 ECGKA--FNNSSTLMKH------------KIIHTGKKPYKCEECGKAFKQSSHLTRHKAI 495
Query: 624 GGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLK 681
TGE Y C +CG + + + H H T C +C K F +L K
Sbjct: 496 ------HTGEKPYKCEECGKAFNHFSALRKHQIIH--TGKKPYKCEECGKAFSQSSTLRK 547
Query: 682 HVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHL 741
H IH Y CE C K F L +H + ++C C + F+ +++ H
Sbjct: 548 HEIIH--TGEKPYKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECGKAFNHFSALRKHK 605
Query: 742 AVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH 801
+ H+ KK Y+C C F + L+ KH + K +KC CG++F +L H
Sbjct: 606 II-HTG-KKPYKCEECGKAFSQSSTLR---KHEIIHTGEKPYKCEECGKAFKWSSKLTVH 660
Query: 802 --ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG-TNGASEQVQKEEVEL 858
I T K C+ C KAF L KH K CG S ++K E+
Sbjct: 661 KVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNNSSTLRKHEI-- 718
Query: 859 QTLLTNSQESHNSHD---GSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGE 915
+ ++S+ + E + T + Y C+ CG A+ + L+ H++ +P
Sbjct: 719 ---IHTGEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLRKHKIIYTGKKP-- 773
Query: 916 SAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLT 975
YKC C + F + L H H G K Y C CG+ F + TL
Sbjct: 774 --------------YKCEECGKAFKQSSHLTRHKAVHTGE-KPYKCGECGKAFNNSSTLK 818
Query: 976 EHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRC--VVCMQTVTSTL 1033
+HK+ H++ + C C + +H +H + ++C C + ++
Sbjct: 819 KHKLIHTRE-KSYKCEECGKAFSNFSALRKHKIIHTGEK----PYKCEECECGKAFNNSS 873
Query: 1034 ELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPY 1090
L H H TG +K YKC C K F + L+K + PY
Sbjct: 874 TLMKHKIIH---TG--------------EKPYKCEECGKGFNNFSTLMKHKIIHTGEKPY 916
Query: 1091 GLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESE 1150
C C K +S T + E E +GK F
Sbjct: 917 -KCEECGKAFKQSS------HLTKHKSIHTGEKPYKCEERGKA-------------FSHF 956
Query: 1151 SELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDE-KKTYQCIKCQMVFYNEWD 1209
S L H + IH P + +E +K Y+C +C F
Sbjct: 957 SRLTKH-RIIHTGK--------------------KPYKCEECEKPYKCEECGKAFNQSSH 995
Query: 1210 IQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFE 1250
+ H H G ++C+ C + F+ + L H I H+ E
Sbjct: 996 LTQHKTIH--TGGKTYKCEECGKAFNHLSALTKHKIIHTGE 1034
Score = 164 bits (415), Expect = 5e-40
Identities = 217/944 (22%), Positives = 345/944 (36%), Gaps = 166/944 (17%)
Query: 426 KTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEV 485
K +H K + + C+ C + +L H K +H + P Y+C C +
Sbjct: 185 KIIHTGK--KPYKCEECGKAFKQSSHLTRH-KAIHTGEKP-----------YKCEECGKA 230
Query: 486 VNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFG 545
N + L++H + H P + C C F S+L +H
Sbjct: 231 FNHFSALRKH-QIIHTGKKP-------YKCEECGKAFSQSSTLRKH-------------- 268
Query: 546 SPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALS 605
++ T ++P Y C + F+++ L KH IH G+K
Sbjct: 269 -EIIHTEEKP----YKYEECGKA--FSNLSALRKH------------EIIHTGQKPYKCE 309
Query: 606 PLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLT 665
A + +S + V +P C +CG + + + H H T
Sbjct: 310 ECGK-AFKWSSKLTVHKVIHTAEKPCK---CEECGKAFKRFSALRKHKIIH--TGKQPYK 363
Query: 666 CPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCT 725
C +C+K F N +L KH IH Y CE C K F L H + +C
Sbjct: 364 CEECSKAFSNFSALRKHEIIH--TGEKPYKCEECGKAFKWSSKLTVHKVIHMEEKPCKCE 421
Query: 726 LCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKC 785
C + F +++ H + H+ KK Y+C C F N + L +KH + K +KC
Sbjct: 422 ECGKAFKHFSALRKHKII-HTG-KKPYKCEECGKAFNNSSTL---MKHKIIHTGKKPYKC 476
Query: 786 IFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG 843
CG++F L H H+ K Y C+ C KAF+ L KH K CG
Sbjct: 477 EECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEECG 536
Query: 844 TN-GASEQVQKEEV------ELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYT 896
S ++K E+ + +SH + + T E Y C+ CG A+
Sbjct: 537 KAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECGKAFN 596
Query: 897 METLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPV 956
+ L+ H++ +P YKC C + F + LR+H H G
Sbjct: 597 HFSALRKHKIIHTGKKP----------------YKCEECGKAFSQSSTLRKHEIIHTGE- 639
Query: 957 KHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNS 1016
K Y C CG+ F LT HKV H+ C C + +H +H +
Sbjct: 640 KPYKCEECGKAFKWSSKLTVHKVIHTAEKPC-KCEECGKAFKHFSALRKHKIIHTGKKP- 697
Query: 1017 LTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGS--AVQTTGRGQHV----QKLYKCASC 1070
++C C + ++ L+ H H TG S + R + +K YKC C
Sbjct: 698 ---YKCEECGKAFNNSSTLRKHEIIH---TGEKSYKCEECALRKHEIIHTGKKPYKCEEC 751
Query: 1071 LKEFRSKQDLVKLDI---NGLPYGLCAGCVNLSKSAS-----PGINVPPGTNRPG-LGQN 1121
K F + L K I PY C C K +S ++ + G G+
Sbjct: 752 GKAFNNSSTLRKHKIIYTGKKPYK-CEECGKAFKQSSHLTRHKAVHTGEKPYKCGECGKA 810
Query: 1122 ENLSAIEGKGKVGGLKTR---CSSCNVKFESESELQNHIQTIHRELVP------------ 1166
N S+ K K+ + + C C F + S L+ H + IH P
Sbjct: 811 FNNSSTLKKHKLIHTREKSYKCEECGKAFSNFSALRKH-KIIHTGEKPYKCEECECGKAF 869
Query: 1167 DSNSTQLKTPQVSPMPRISPSQSDE--------------------KKTYQCIKCQMVFYN 1206
+++ST +K + + P + +E +K Y+C +C F
Sbjct: 870 NNSSTLMKHKIIHTGEK--PYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQ 927
Query: 1207 EWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHS------FEGMGGTFKCPV 1260
+ H + H ++ ++C+ + F ++L H I H+ E +KC
Sbjct: 928 SSHLTKHKSIHTGEKP--YKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEE 985
Query: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C F Q++ L QH G K Y C +C + F + L H
Sbjct: 986 CGKAFNQSSHLTQHKTIHTG--GKTYKCEECGKAFNHLSALTKH 1027
Score = 127 bits (318), Expect = 9e-29
Identities = 115/456 (25%), Positives = 179/456 (39%), Gaps = 92/456 (20%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F+ S +T HK+ + + P C + K ++ +
Sbjct: 639 EKPYKCEECGKAFKWSSKLTVHKV--------IHTAEKP-CKCEECGKAFKHFSALRKHK 689
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYL-KH-------------------HEQSHSDK 143
G++ PY C+ C K+F+ S L KH HE H+ K
Sbjct: 690 IIHTGKK------PYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGK 743
Query: 144 LPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYK 203
P+KC C + F + + +H ++TG K Y C EC AF +S HL H HT KPYK
Sbjct: 744 KPYKCEECGKAFNNSSTLRKHKIIYTGKKPYKCEECGKAFKQSSHLTRHKAVHTGEKPYK 803
Query: 204 CAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQK 263
C C + F +SS+L H +H R K + KC +C + F L+K
Sbjct: 804 CGECGKAFNNSSTLKKHKLIHTREK----------------SYKCEECGKAFSNFSALRK 847
Query: 264 ----HIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESF 319
H E +C E C + F ++LM H + +H+GEK C C + F
Sbjct: 848 HKIIHTGEKPYKCEECE---------CGKAFNNSSTLMKH-KIIHTGEKPYKCEECGKGF 897
Query: 320 HTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPI 377
+ L H H ++P C + S+L+ S P
Sbjct: 898 NNFSTLMKHKIIHTGEKPYKCEECG------------KAFKQSSHLTKHKSIHTGEKPYK 945
Query: 378 PKSRGR-----KRAAQQTPDMTGP---SSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMH 429
+ RG+ R + TG ++ + Y C C K F+ + L H KT+H
Sbjct: 946 CEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGK-AFNQSSHLTQH-KTIH 1003
Query: 430 LDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDP 465
+ + C+ C + L L +H K +H + P
Sbjct: 1004 TG--GKTYKCEECGKAFNHLSALTKH-KIIHTGEKP 1036
Score = 124 bits (312), Expect = 5e-28
Identities = 125/548 (22%), Positives = 197/548 (35%), Gaps = 112/548 (20%)
Query: 43 DEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHG 102
+E + C+ C + F S + +HKI
Sbjct: 582 EEKPYKCEECGKAFNHFSALRKHKI----------------------------------- 606
Query: 103 EGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRD 162
G++ PY C+ C K+FS+ S L+ HE H+ + P+KC C + FK
Sbjct: 607 --IHTGKK------PYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLT 658
Query: 163 RHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQ 222
H +HT +K C EC AF L+ H HT KPYKC C + F +SS+L H
Sbjct: 659 VHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNNSSTLRKHEI 718
Query: 223 VHERNKDGSQSGSRMEDWKM----KDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDR 278
+H K + ++ K KC +C + F+ L+KH +
Sbjct: 719 IHTGEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLRKHKI-------IYTGK 771
Query: 279 AALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESC 338
+C C + F + + L H + VH+GEK C C ++F+ L H H + +S
Sbjct: 772 KPYKCEECGKAFKQSSHLTRH-KAVHTGEKPYKCGECGKAFNNSSTLKKHKLIHTREKS- 829
Query: 339 NHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMV----EAAPPIPKSRGRKRAAQQTPDMT 394
Y SN S + E + K + M
Sbjct: 830 ------------YKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMK 877
Query: 395 GPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNE 454
+ Y C C K F++ + L H K +H E+ + C+ C + +L +
Sbjct: 878 HKIIHTGEKPYKCEECGKG-FNNFSTLMKH-KIIHTG--EKPYKCEECGKAFKQSSHLTK 933
Query: 455 HLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANP--AAKDSNA 512
H K +H + P Y+C + + + L +H R H P +
Sbjct: 934 H-KSIHTGEKP-----------YKCEERGKAFSHFSRLTKH-RIIHTGKKPYKCEECEKP 980
Query: 513 FFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFN 572
+ C C F S L +H + +H +G + Y C C + FN
Sbjct: 981 YKCEECGKAFNQSSHLTQH-KTIH---TGGK---------------TYKCEECGKA--FN 1019
Query: 573 SVLKLNKH 580
+ L KH
Sbjct: 1020 HLSALTKH 1027
Score = 95.9 bits (237), Expect = 2e-19
Identities = 133/590 (22%), Positives = 214/590 (36%), Gaps = 108/590 (18%)
Query: 728 QEVFDS--KVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHL--ENQGKVH 783
Q + DS ++ ++ + H N + C S N +E + + K N QGK+
Sbjct: 110 QSIKDSFQEIILRTYARCGHKNLRLRKDCESVNEGKMHE---EAYNKLNQCWTTTQGKIF 166
Query: 784 KC-----IFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETK 838
+C +F S ++ I T K Y C+ C KAF L +H K
Sbjct: 167 QCNKYVKVFHKYSNSNRYKI---IHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYK 223
Query: 839 TPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTME 898
CG +H S + + T + Y C+ CG A++
Sbjct: 224 CEECG---------------------KAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQS 262
Query: 899 TLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKH 958
+ L+ H++ +P YK C + F + + LR+H H G K
Sbjct: 263 STLRKHEIIHTEEKP----------------YKYEECGKAFSNLSALRKHEIIHTGQ-KP 305
Query: 959 YMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLT 1018
Y C CG+ F LT HKV H+ C C + +H +H +
Sbjct: 306 YKCEECGKAFKWSSKLTVHKVIHTAEKPC-KCEECGKAFKRFSALRKHKIIHTGKQP--- 361
Query: 1019 GFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQ 1078
++C C + ++ L+ H H TG +K YKC C K F+
Sbjct: 362 -YKCEECSKAFSNFSALRKHEIIH------------TG-----EKPYKCEECGKAFKWSS 403
Query: 1079 DLVKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV---GG 1135
L + + C C K+ ++ SA+ K K+ G
Sbjct: 404 KLTVHKVIHMEEKPCK-CEECGKAF------------------KHFSALR-KHKIIHTGK 443
Query: 1136 LKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKT-PQVSPMPRISPSQSDEKKT 1194
+C C F + S L H + IH P K Q S + R + EK
Sbjct: 444 KPYKCEECGKAFNNSSTLMKH-KIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKP- 501
Query: 1195 YQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGG 1254
Y+C +C F + ++ H H + ++C+ C + F + L+ H I H+ E
Sbjct: 502 YKCEECGKAFNHFSALRKHQIIHTGKKP--YKCEECGKAFSQSSTLRKHEIIHTGEK--- 556
Query: 1255 TFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+KC C F ++ L +H E+K Y C +C + F + L+ H
Sbjct: 557 PYKCEECGKAFKWSSHLTRH--KVIHTEEKPYKCEECGKAFNHFSALRKH 604
>gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]
Length = 1119
Score = 249 bits (637), Expect = 9e-66
Identities = 281/1213 (23%), Positives = 440/1213 (36%), Gaps = 212/1213 (17%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+ C C KSF LS L H++ H + +KC + FK + +H +HT DK Y
Sbjct: 47 FKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYK 106
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
+C AF S H + HT P++C C + F SS+L H ++H K
Sbjct: 107 KCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEK--------- 157
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
T KC +C + F + H H P +C C + F ++L
Sbjct: 158 -------TYKCEECGKAFKGSSNFNAH-KVIHTAEKP------YKCEDCGKTFNHFSALR 203
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
H + +H+G+K C ++F L H H ++P C
Sbjct: 204 KH-KIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPYKCEECG------------K 250
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLF 415
+ S L+V P + G K +Q + K Y C C K F
Sbjct: 251 AFKWSSKLTVHKVVHTGEKPYKCEECG-KAFSQFSTLKKHKIIHTGKKPYKCEECGK-AF 308
Query: 416 SSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAI 475
+S + L H K +H E+ + C+ C + +L H K +H + P
Sbjct: 309 NSSSTLMKH-KIIHTG--EKPYKCEECGKAFRQSSHLTRH-KAIHTGEKP---------- 354
Query: 476 VYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQV 535
Y+C C + N + L+ H + H P + C C F S+L H
Sbjct: 355 -YKCEECGKAFNHFSDLRRH-KIIHTGKKP-------YKCEECGKAFSQSSTLRNH---- 401
Query: 536 HCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYI 595
++ T ++P Y C C + ++S L ++K I K
Sbjct: 402 -----------QIIHTGEKP----YKCEECGKAFKWSSKLTVHKVIHTGEKPCKCE---- 442
Query: 596 HNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKT 655
GK + S L + T K+ Y C +CG + + H
Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKL--------------YKCEECGKAFNNSSILAKHKII 488
Query: 656 HLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLD 715
H T C +C K F L +H IH Y CE C K F+ L++H +
Sbjct: 489 H--TGKKPYKCEECGKAFRQSSHLTRHKAIH--TGEKPYKCEECGKAFSHFSALRRHKII 544
Query: 716 MHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNH 775
++C C + F +++ H + H+ EK Y+C C F+ + L + H
Sbjct: 545 HTGKKPYKCEECGKAFSHFSALRRHKII-HTGEKP-YKCEECGKAFKWSSKLTV---HKV 599
Query: 776 LENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHC 833
+ K KC CG+SF L+ H I T K Y C+ C KAF++ L KH
Sbjct: 600 IHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTG 659
Query: 834 VFETKTPNCGT--NGASEQVQKEEVELQTLLTNSQE-----SHNSHDGSEEDVDTSEPMY 886
K CG +S+ + + +E H S + + T + Y
Sbjct: 660 EKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGKKPY 719
Query: 887 GCDICGAAYTMETLLQNHQLRDHNIRPGE------------SAIVKKKAELIKGNYKCNV 934
C+ CG A++ + L+ H++ +P + V K + KC
Sbjct: 720 KCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEE 779
Query: 935 CSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICK 994
C + F + LR+H H G K Y C CG+ F TL +HK+ H+ C C
Sbjct: 780 CGKAFKHFSALRKHKIIHTGK-KPYKCEECGKAFNDSSTLMKHKIIHT-GKKPYKCAECG 837
Query: 995 MPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQT 1054
+ H +H + ++C C + ++ LK H H +
Sbjct: 838 KAFKQSSHLTRHKAIHTGEK----PYKCEECGKDFNNSSTLKKHKLIHTR---------- 883
Query: 1055 TGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPGINVPP 1111
+KLYKC C+K F + L+K + PY C C K +S
Sbjct: 884 -------EKLYKCEECVKAFNNFSALMKHKIIHTGEKPY-KCEECGKAFKWSSK------ 929
Query: 1112 GTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNST 1171
L +++ + G +C C+ F+ S L+ H + IH
Sbjct: 930 ------LTEHKVI-------HTGEKPCKCEECDKAFKHFSALRKH-KVIH---------- 965
Query: 1172 QLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCS 1231
KK YQC +C F N + H H ++ ++C+ C
Sbjct: 966 ------------------TGKKPYQCDECGKAFNNSSTLTKHKIIHTGEK--PYKCEECG 1005
Query: 1232 QTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQC 1291
+ F + L H I HS E +KC C F Q++ L +H G +K Y C +C
Sbjct: 1006 KAFSQSSILTKHKIIHSVE---KPYKCEECGKAFNQSSHLTRHKTIHTG--EKPYKCEEC 1060
Query: 1292 PQKFFFQTELQNH 1304
+ F + L H
Sbjct: 1061 GKAFIQCSYLIRH 1073
Score = 249 bits (635), Expect = 2e-65
Identities = 265/1098 (24%), Positives = 401/1098 (36%), Gaps = 173/1098 (15%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E C+ C + F S++T+HK ++ G C S+ + H
Sbjct: 128 ETPFRCEECGKAFNQSSNLTDHK----RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTA 183
Query: 104 GCDFGEEEGGPGL-----------------PYPCQFCDKSFSRLSYLKHHEQSHSDKLPF 146
+ E+ G PY + C K+FS+ S L+ HE H+ + P+
Sbjct: 184 EKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPY 243
Query: 147 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAI 206
KC C + FK H +HTG+K Y C EC AFS+ LK H HT KPYKC
Sbjct: 244 KCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEE 303
Query: 207 CRRGFLSSSSLHGHMQVHERNKD--------GSQSGSRMEDWKMKDT----QKCSQCEEG 254
C + F SSS+L H +H K + S + K T KC +C +
Sbjct: 304 CGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKA 363
Query: 255 FDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSI 314
F+ DL++H H P +C C + F + ++L NH + +H+GEK C
Sbjct: 364 FNHFSDLRRHKI-IHTGKKP------YKCEECGKAFSQSSTLRNH-QIIHTGEKPYKCEE 415
Query: 315 CSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAA 374
C ++F +L H H + C + S+ + ++
Sbjct: 416 CGKAFKWSSKLTVHKVIHTGEKPCKCEECGK----AFKHFSA--------LRKHKVIHTR 463
Query: 375 PPIPKSRGRKRAAQQTPDMTGPSS-KQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKP 433
+ K +A + + K Y C C K F + L H K +H
Sbjct: 464 EKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKA-FRQSSHLTRH-KAIHTG-- 519
Query: 434 EQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQ 493
E+ + C+ C + L H K +H + P Y+C C + + + L+
Sbjct: 520 EKPYKCEECGKAFSHFSALRRH-KIIHTGKKP-----------YKCEECGKAFSHFSALR 567
Query: 494 EHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFGS 546
H + H P + C C F S L H + +H C+ G F
Sbjct: 568 RH-KIIHTGEKP-------YKCEECGKAFKWSSKLTVH-KVIHTAEKPCKCEECGKSF-K 617
Query: 547 PVLGTPKEPVV----EVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSR 602
K V+ ++Y C C + FNS L KH IH G+K
Sbjct: 618 HFSALRKHKVIHTREKLYKCEECVKA--FNSFSALMKH------------KVIHTGEKPY 663
Query: 603 ALSPLSPVAIEQTSLKMMQAV--GGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV 660
+ L + + + G P + C +CG + + + H H T
Sbjct: 664 KCEECGKAFKWSSKLTVHKVIHTGEKPCK------CEECGKAFKHFSALRKHKVIH--TG 715
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C +C K F SL KH IH Y CE C K F + L H +
Sbjct: 716 KKPYKCEECGKAFSQSSSLRKHEIIHS--GEKPYKCEECGKAFKWLSKLTVHKVIHTAEK 773
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
+C C + F +++ H + H+ KK Y+C C F + + L +KH +
Sbjct: 774 PCKCEECGKAFKHFSALRKHKII-HTG-KKPYKCEECGKAFNDSSTL---MKHKIIHTGK 828
Query: 781 KVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETK 838
K +KC CG++F L H H+ K Y C+ C K F+ L+KH K K
Sbjct: 829 KPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKH---KLIHTREK 885
Query: 839 TPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTME 898
C E+ K L+ + + + T E Y C+ CG A+
Sbjct: 886 LYKC------EECVKAFNNFSALMKH------------KIIHTGEKPYKCEECGKAFKWS 927
Query: 899 TLLQNHQLRDHNIRPGE-----------SAIVKKKA-ELIKGNYKCNVCSRTFFSENGLR 946
+ L H++ +P + SA+ K K K Y+C+ C + F + + L
Sbjct: 928 SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLT 987
Query: 947 EHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEH 1006
+H H G K Y C CG+ F LT+HK+ HS C C H
Sbjct: 988 KHKIIHTGE-KPYKCEECGKAFSQSSILTKHKIIHSVEKPY-KCEECGKAFNQSSHLTRH 1045
Query: 1007 CQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM-QKTGNGSAVQTTGRGQHV---- 1061
+H + ++C C + L H T H +K N V H
Sbjct: 1046 KTIHTGEKP----YKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK 1101
Query: 1062 -----QKLYKCASCLKEF 1074
+K YKC C K F
Sbjct: 1102 TIHTGEKPYKCEECAKAF 1119
Score = 192 bits (489), Expect = 1e-48
Identities = 228/948 (24%), Positives = 338/948 (35%), Gaps = 187/948 (19%)
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
K T+ CI C+K F L+ L H K +H+ + + C+ + S L +H K +H
Sbjct: 44 KKTFKCIKCSKSFF-MLSCLIRH-KRIHI--RQNIYKCEERGKAFKSFSTLTKH-KIIHT 98
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
P Y+ C +T +H R G F C C
Sbjct: 99 EDKP-----------YKYKKCGNAFKFSSTFTKHKRIHTG--------ETPFRCEECGKA 139
Query: 522 FLTDSSLEEHIRQVH-------CDLSGSRF-------GSPVLGTPKEPVVEVYSCSYCTN 567
F S+L +H +++H C+ G F V+ T ++P Y C C
Sbjct: 140 FNQSSNLTDH-KRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP----YKCEDCGK 194
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+ FN L KH IH GKK + ++L+ + +
Sbjct: 195 T--FNHFSALRKH------------KIIHTGKKPYKREECGKAFSQSSTLRKHEII---- 236
Query: 628 ARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTI 685
TGE Y C +CG + H H T C +C K F +L KH I
Sbjct: 237 --HTGEKPYKCEECGKAFKWSSKLTVHKVVH--TGEKPYKCEECGKAFSQFSTLKKHKII 292
Query: 686 HFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKH 745
H Y CE C K F S L KH + ++C C + F + H A+ H
Sbjct: 293 H--TGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAI-H 349
Query: 746 SNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--IT 803
+ EK Y+C C F + +DL+ +H + K +KC CG++F L+ H I
Sbjct: 350 TGEKP-YKCEECGKAFNHFSDLR---RHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIH 405
Query: 804 THSKKYNCKFCSKAF--------HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEE 855
T K Y C+ C KAF H +I H EK C K CG
Sbjct: 406 TGEKPYKCEECGKAFKWSSKLTVHKVI----HTGEKPC----KCEECG------------ 445
Query: 856 VELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGE 915
H S + + T E +Y C+ CG A+ ++L H++ +P
Sbjct: 446 ---------KAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKP-- 494
Query: 916 SAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLT 975
YKC C + F + L H H G K Y C CG+ F L
Sbjct: 495 --------------YKCEECGKAFRQSSHLTRHKAIHTGE-KPYKCEECGKAFSHFSALR 539
Query: 976 EHKVTHSKSLDTGNCRICKMPLQSEE-----EFLEHCQMHPDLRNSLTGFRCVVCMQTVT 1030
HK+ H TG K P + EE + H + ++C C +
Sbjct: 540 RHKIIH-----TG-----KKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFK 589
Query: 1031 STLELKIHGTFH-------MQKTGNGSAVQTTGRGQHV----QKLYKCASCLKEFRSKQD 1079
+ +L +H H ++ G + R V +KLYKC C+K F S
Sbjct: 590 WSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSA 649
Query: 1080 LVK---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGL 1136
L+K + PY C C K +S + G
Sbjct: 650 LMKHKVIHTGEKPY-KCEECGKAFKWSSK-------------------LTVHKVIHTGEK 689
Query: 1137 KTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQ 1196
+C C F+ S L+ H + IH P K S R +K Y+
Sbjct: 690 PCKCEECGKAFKHFSALRKH-KVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYK 748
Query: 1197 CIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTF 1256
C +C F + VH H ++ +C+ C + F + L+ H I H+ + +
Sbjct: 749 CEECGKAFKWLSKLTVHKVIHTAEKPC--KCEECGKAFKHFSALRKHKIIHTGK---KPY 803
Query: 1257 KCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
KC C F ++ L +H G+ K Y C +C + F + L H
Sbjct: 804 KCEECGKAFNDSSTLMKHKIIHTGK--KPYKCAECGKAFKQSSHLTRH 849
Score = 89.4 bits (220), Expect = 2e-17
Identities = 121/573 (21%), Positives = 195/573 (34%), Gaps = 109/573 (19%)
Query: 799 QCHITTHSKKYNCKFCSKAFH-----------------------AIILLEKHLREKHCVF 835
QC T K + C K FH + +L +R K
Sbjct: 11 QCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHI 70
Query: 836 ETKTPNCGTNGAS----------EQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPM 885
C G + + + E+ + + +S + + T E
Sbjct: 71 RQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETP 130
Query: 886 YGCDICGAAYTMETLLQNHQLRDHNIRPGESAI-VKKKAELIKGN--------------- 929
+ C+ CG A+ + L +H+ I GE ++ + KG+
Sbjct: 131 FRCEECGKAFNQSSNLTDHK----RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP 186
Query: 930 YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN 989
YKC C +TF + LR+H H G K Y CG+ F TL +H++ H+
Sbjct: 187 YKCEDCGKTFNHFSALRKHKIIHTGK-KPYKREECGKAFSQSSTLRKHEIIHTGE-KPYK 244
Query: 990 CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNG 1049
C C + + H +H + ++C C + + LK H H K
Sbjct: 245 CEECGKAFKWSSKLTVHKVVHTGEK----PYKCEECGKAFSQFSTLKKHKIIHTGK---- 296
Query: 1050 SAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPG 1106
K YKC C K F S L+K + PY C C + +S
Sbjct: 297 -------------KPYKCEECGKAFNSSSTLMKHKIIHTGEKPY-KCEECGKAFRQSS-- 340
Query: 1107 INVPPGTNRPGLGQNENLSAIEGKGK---------------VGGLKTRCSSCNVKFESES 1151
T + E E GK G +C C F S
Sbjct: 341 ----HLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSS 396
Query: 1152 ELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQ 1211
L+NH Q IH P K + S + +K +C +C F + ++
Sbjct: 397 TLRNH-QIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALR 455
Query: 1212 VHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1271
H H ++ ++C+ C + F++ + L H I H+ + +KC C F Q++ L
Sbjct: 456 KHKVIHTREK--LYKCEECGKAFNNSSILAKHKIIHTGK---KPYKCEECGKAFRQSSHL 510
Query: 1272 QQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+H A +K Y C +C + F + L+ H
Sbjct: 511 TRH--KAIHTGEKPYKCEECGKAFSHFSALRRH 541
>gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]
Length = 1119
Score = 249 bits (637), Expect = 9e-66
Identities = 281/1213 (23%), Positives = 440/1213 (36%), Gaps = 212/1213 (17%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+ C C KSF LS L H++ H + +KC + FK + +H +HT DK Y
Sbjct: 47 FKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYK 106
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
+C AF S H + HT P++C C + F SS+L H ++H K
Sbjct: 107 KCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEK--------- 157
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
T KC +C + F + H H P +C C + F ++L
Sbjct: 158 -------TYKCEECGKAFKGSSNFNAH-KVIHTAEKP------YKCEDCGKTFNHFSALR 203
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
H + +H+G+K C ++F L H H ++P C
Sbjct: 204 KH-KIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPYKCEECG------------K 250
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLF 415
+ S L+V P + G K +Q + K Y C C K F
Sbjct: 251 AFKWSSKLTVHKVVHTGEKPYKCEECG-KAFSQFSTLKKHKIIHTGKKPYKCEECGK-AF 308
Query: 416 SSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAI 475
+S + L H K +H E+ + C+ C + +L H K +H + P
Sbjct: 309 NSSSTLMKH-KIIHTG--EKPYKCEECGKAFRQSSHLTRH-KAIHTGEKP---------- 354
Query: 476 VYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQV 535
Y+C C + N + L+ H + H P + C C F S+L H
Sbjct: 355 -YKCEECGKAFNHFSDLRRH-KIIHTGKKP-------YKCEECGKAFSQSSTLRNH---- 401
Query: 536 HCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYI 595
++ T ++P Y C C + ++S L ++K I K
Sbjct: 402 -----------QIIHTGEKP----YKCEECGKAFKWSSKLTVHKVIHTGEKPCKCE---- 442
Query: 596 HNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKT 655
GK + S L + T K+ Y C +CG + + H
Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKL--------------YKCEECGKAFNNSSILAKHKII 488
Query: 656 HLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLD 715
H T C +C K F L +H IH Y CE C K F+ L++H +
Sbjct: 489 H--TGKKPYKCEECGKAFRQSSHLTRHKAIH--TGEKPYKCEECGKAFSHFSALRRHKII 544
Query: 716 MHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNH 775
++C C + F +++ H + H+ EK Y+C C F+ + L + H
Sbjct: 545 HTGKKPYKCEECGKAFSHFSALRRHKII-HTGEKP-YKCEECGKAFKWSSKLTV---HKV 599
Query: 776 LENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHC 833
+ K KC CG+SF L+ H I T K Y C+ C KAF++ L KH
Sbjct: 600 IHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTG 659
Query: 834 VFETKTPNCGT--NGASEQVQKEEVELQTLLTNSQE-----SHNSHDGSEEDVDTSEPMY 886
K CG +S+ + + +E H S + + T + Y
Sbjct: 660 EKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGKKPY 719
Query: 887 GCDICGAAYTMETLLQNHQLRDHNIRPGE------------SAIVKKKAELIKGNYKCNV 934
C+ CG A++ + L+ H++ +P + V K + KC
Sbjct: 720 KCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEE 779
Query: 935 CSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICK 994
C + F + LR+H H G K Y C CG+ F TL +HK+ H+ C C
Sbjct: 780 CGKAFKHFSALRKHKIIHTGK-KPYKCEECGKAFNDSSTLMKHKIIHT-GKKPYKCAECG 837
Query: 995 MPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQT 1054
+ H +H + ++C C + ++ LK H H +
Sbjct: 838 KAFKQSSHLTRHKAIHTGEK----PYKCEECGKDFNNSSTLKKHKLIHTR---------- 883
Query: 1055 TGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPGINVPP 1111
+KLYKC C+K F + L+K + PY C C K +S
Sbjct: 884 -------EKLYKCEECVKAFNNFSALMKHKIIHTGEKPY-KCEECGKAFKWSSK------ 929
Query: 1112 GTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNST 1171
L +++ + G +C C+ F+ S L+ H + IH
Sbjct: 930 ------LTEHKVI-------HTGEKPCKCEECDKAFKHFSALRKH-KVIH---------- 965
Query: 1172 QLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCS 1231
KK YQC +C F N + H H ++ ++C+ C
Sbjct: 966 ------------------TGKKPYQCDECGKAFNNSSTLTKHKIIHTGEK--PYKCEECG 1005
Query: 1232 QTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQC 1291
+ F + L H I HS E +KC C F Q++ L +H G +K Y C +C
Sbjct: 1006 KAFSQSSILTKHKIIHSVE---KPYKCEECGKAFNQSSHLTRHKTIHTG--EKPYKCEEC 1060
Query: 1292 PQKFFFQTELQNH 1304
+ F + L H
Sbjct: 1061 GKAFIQCSYLIRH 1073
Score = 249 bits (635), Expect = 2e-65
Identities = 265/1098 (24%), Positives = 401/1098 (36%), Gaps = 173/1098 (15%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E C+ C + F S++T+HK ++ G C S+ + H
Sbjct: 128 ETPFRCEECGKAFNQSSNLTDHK----RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTA 183
Query: 104 GCDFGEEEGGPGL-----------------PYPCQFCDKSFSRLSYLKHHEQSHSDKLPF 146
+ E+ G PY + C K+FS+ S L+ HE H+ + P+
Sbjct: 184 EKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPY 243
Query: 147 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAI 206
KC C + FK H +HTG+K Y C EC AFS+ LK H HT KPYKC
Sbjct: 244 KCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEE 303
Query: 207 CRRGFLSSSSLHGHMQVHERNKD--------GSQSGSRMEDWKMKDT----QKCSQCEEG 254
C + F SSS+L H +H K + S + K T KC +C +
Sbjct: 304 CGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKA 363
Query: 255 FDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSI 314
F+ DL++H H P +C C + F + ++L NH + +H+GEK C
Sbjct: 364 FNHFSDLRRHKI-IHTGKKP------YKCEECGKAFSQSSTLRNH-QIIHTGEKPYKCEE 415
Query: 315 CSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAA 374
C ++F +L H H + C + S+ + ++
Sbjct: 416 CGKAFKWSSKLTVHKVIHTGEKPCKCEECGK----AFKHFSA--------LRKHKVIHTR 463
Query: 375 PPIPKSRGRKRAAQQTPDMTGPSS-KQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKP 433
+ K +A + + K Y C C K F + L H K +H
Sbjct: 464 EKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKA-FRQSSHLTRH-KAIHTG-- 519
Query: 434 EQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQ 493
E+ + C+ C + L H K +H + P Y+C C + + + L+
Sbjct: 520 EKPYKCEECGKAFSHFSALRRH-KIIHTGKKP-----------YKCEECGKAFSHFSALR 567
Query: 494 EHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFGS 546
H + H P + C C F S L H + +H C+ G F
Sbjct: 568 RH-KIIHTGEKP-------YKCEECGKAFKWSSKLTVH-KVIHTAEKPCKCEECGKSF-K 617
Query: 547 PVLGTPKEPVV----EVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSR 602
K V+ ++Y C C + FNS L KH IH G+K
Sbjct: 618 HFSALRKHKVIHTREKLYKCEECVKA--FNSFSALMKH------------KVIHTGEKPY 663
Query: 603 ALSPLSPVAIEQTSLKMMQAV--GGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV 660
+ L + + + G P + C +CG + + + H H T
Sbjct: 664 KCEECGKAFKWSSKLTVHKVIHTGEKPCK------CEECGKAFKHFSALRKHKVIH--TG 715
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C +C K F SL KH IH Y CE C K F + L H +
Sbjct: 716 KKPYKCEECGKAFSQSSSLRKHEIIHS--GEKPYKCEECGKAFKWLSKLTVHKVIHTAEK 773
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
+C C + F +++ H + H+ KK Y+C C F + + L +KH +
Sbjct: 774 PCKCEECGKAFKHFSALRKHKII-HTG-KKPYKCEECGKAFNDSSTL---MKHKIIHTGK 828
Query: 781 KVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETK 838
K +KC CG++F L H H+ K Y C+ C K F+ L+KH K K
Sbjct: 829 KPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKH---KLIHTREK 885
Query: 839 TPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTME 898
C E+ K L+ + + + T E Y C+ CG A+
Sbjct: 886 LYKC------EECVKAFNNFSALMKH------------KIIHTGEKPYKCEECGKAFKWS 927
Query: 899 TLLQNHQLRDHNIRPGE-----------SAIVKKKA-ELIKGNYKCNVCSRTFFSENGLR 946
+ L H++ +P + SA+ K K K Y+C+ C + F + + L
Sbjct: 928 SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLT 987
Query: 947 EHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEH 1006
+H H G K Y C CG+ F LT+HK+ HS C C H
Sbjct: 988 KHKIIHTGE-KPYKCEECGKAFSQSSILTKHKIIHSVEKPY-KCEECGKAFNQSSHLTRH 1045
Query: 1007 CQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM-QKTGNGSAVQTTGRGQHV---- 1061
+H + ++C C + L H T H +K N V H
Sbjct: 1046 KTIHTGEKP----YKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK 1101
Query: 1062 -----QKLYKCASCLKEF 1074
+K YKC C K F
Sbjct: 1102 TIHTGEKPYKCEECAKAF 1119
Score = 192 bits (489), Expect = 1e-48
Identities = 228/948 (24%), Positives = 338/948 (35%), Gaps = 187/948 (19%)
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
K T+ CI C+K F L+ L H K +H+ + + C+ + S L +H K +H
Sbjct: 44 KKTFKCIKCSKSFF-MLSCLIRH-KRIHI--RQNIYKCEERGKAFKSFSTLTKH-KIIHT 98
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
P Y+ C +T +H R G F C C
Sbjct: 99 EDKP-----------YKYKKCGNAFKFSSTFTKHKRIHTG--------ETPFRCEECGKA 139
Query: 522 FLTDSSLEEHIRQVH-------CDLSGSRF-------GSPVLGTPKEPVVEVYSCSYCTN 567
F S+L +H +++H C+ G F V+ T ++P Y C C
Sbjct: 140 FNQSSNLTDH-KRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP----YKCEDCGK 194
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+ FN L KH IH GKK + ++L+ + +
Sbjct: 195 T--FNHFSALRKH------------KIIHTGKKPYKREECGKAFSQSSTLRKHEII---- 236
Query: 628 ARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTI 685
TGE Y C +CG + H H T C +C K F +L KH I
Sbjct: 237 --HTGEKPYKCEECGKAFKWSSKLTVHKVVH--TGEKPYKCEECGKAFSQFSTLKKHKII 292
Query: 686 HFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKH 745
H Y CE C K F S L KH + ++C C + F + H A+ H
Sbjct: 293 H--TGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAI-H 349
Query: 746 SNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--IT 803
+ EK Y+C C F + +DL+ +H + K +KC CG++F L+ H I
Sbjct: 350 TGEKP-YKCEECGKAFNHFSDLR---RHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIH 405
Query: 804 THSKKYNCKFCSKAF--------HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEE 855
T K Y C+ C KAF H +I H EK C K CG
Sbjct: 406 TGEKPYKCEECGKAFKWSSKLTVHKVI----HTGEKPC----KCEECG------------ 445
Query: 856 VELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGE 915
H S + + T E +Y C+ CG A+ ++L H++ +P
Sbjct: 446 ---------KAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKP-- 494
Query: 916 SAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLT 975
YKC C + F + L H H G K Y C CG+ F L
Sbjct: 495 --------------YKCEECGKAFRQSSHLTRHKAIHTGE-KPYKCEECGKAFSHFSALR 539
Query: 976 EHKVTHSKSLDTGNCRICKMPLQSEE-----EFLEHCQMHPDLRNSLTGFRCVVCMQTVT 1030
HK+ H TG K P + EE + H + ++C C +
Sbjct: 540 RHKIIH-----TG-----KKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFK 589
Query: 1031 STLELKIHGTFH-------MQKTGNGSAVQTTGRGQHV----QKLYKCASCLKEFRSKQD 1079
+ +L +H H ++ G + R V +KLYKC C+K F S
Sbjct: 590 WSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSA 649
Query: 1080 LVK---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGL 1136
L+K + PY C C K +S + G
Sbjct: 650 LMKHKVIHTGEKPY-KCEECGKAFKWSSK-------------------LTVHKVIHTGEK 689
Query: 1137 KTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQ 1196
+C C F+ S L+ H + IH P K S R +K Y+
Sbjct: 690 PCKCEECGKAFKHFSALRKH-KVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYK 748
Query: 1197 CIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTF 1256
C +C F + VH H ++ +C+ C + F + L+ H I H+ + +
Sbjct: 749 CEECGKAFKWLSKLTVHKVIHTAEKPC--KCEECGKAFKHFSALRKHKIIHTGK---KPY 803
Query: 1257 KCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
KC C F ++ L +H G+ K Y C +C + F + L H
Sbjct: 804 KCEECGKAFNDSSTLMKHKIIHTGK--KPYKCAECGKAFKQSSHLTRH 849
Score = 89.4 bits (220), Expect = 2e-17
Identities = 121/573 (21%), Positives = 195/573 (34%), Gaps = 109/573 (19%)
Query: 799 QCHITTHSKKYNCKFCSKAFH-----------------------AIILLEKHLREKHCVF 835
QC T K + C K FH + +L +R K
Sbjct: 11 QCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHI 70
Query: 836 ETKTPNCGTNGAS----------EQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPM 885
C G + + + E+ + + +S + + T E
Sbjct: 71 RQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETP 130
Query: 886 YGCDICGAAYTMETLLQNHQLRDHNIRPGESAI-VKKKAELIKGN--------------- 929
+ C+ CG A+ + L +H+ I GE ++ + KG+
Sbjct: 131 FRCEECGKAFNQSSNLTDHK----RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP 186
Query: 930 YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN 989
YKC C +TF + LR+H H G K Y CG+ F TL +H++ H+
Sbjct: 187 YKCEDCGKTFNHFSALRKHKIIHTGK-KPYKREECGKAFSQSSTLRKHEIIHTGE-KPYK 244
Query: 990 CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNG 1049
C C + + H +H + ++C C + + LK H H K
Sbjct: 245 CEECGKAFKWSSKLTVHKVVHTGEK----PYKCEECGKAFSQFSTLKKHKIIHTGK---- 296
Query: 1050 SAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPG 1106
K YKC C K F S L+K + PY C C + +S
Sbjct: 297 -------------KPYKCEECGKAFNSSSTLMKHKIIHTGEKPY-KCEECGKAFRQSS-- 340
Query: 1107 INVPPGTNRPGLGQNENLSAIEGKGK---------------VGGLKTRCSSCNVKFESES 1151
T + E E GK G +C C F S
Sbjct: 341 ----HLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSS 396
Query: 1152 ELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQ 1211
L+NH Q IH P K + S + +K +C +C F + ++
Sbjct: 397 TLRNH-QIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALR 455
Query: 1212 VHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1271
H H ++ ++C+ C + F++ + L H I H+ + +KC C F Q++ L
Sbjct: 456 KHKVIHTREK--LYKCEECGKAFNNSSILAKHKIIHTGK---KPYKCEECGKAFRQSSHL 510
Query: 1272 QQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+H A +K Y C +C + F + L+ H
Sbjct: 511 TRH--KAIHTGEKPYKCEECGKAFSHFSALRRH 541
>gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo
sapiens]
Length = 1119
Score = 249 bits (637), Expect = 9e-66
Identities = 281/1213 (23%), Positives = 440/1213 (36%), Gaps = 212/1213 (17%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+ C C KSF LS L H++ H + +KC + FK + +H +HT DK Y
Sbjct: 47 FKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYK 106
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
+C AF S H + HT P++C C + F SS+L H ++H K
Sbjct: 107 KCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEK--------- 157
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
T KC +C + F + H H P +C C + F ++L
Sbjct: 158 -------TYKCEECGKAFKGSSNFNAH-KVIHTAEKP------YKCEDCGKTFNHFSALR 203
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
H + +H+G+K C ++F L H H ++P C
Sbjct: 204 KH-KIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPYKCEECG------------K 250
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLF 415
+ S L+V P + G K +Q + K Y C C K F
Sbjct: 251 AFKWSSKLTVHKVVHTGEKPYKCEECG-KAFSQFSTLKKHKIIHTGKKPYKCEECGK-AF 308
Query: 416 SSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAI 475
+S + L H K +H E+ + C+ C + +L H K +H + P
Sbjct: 309 NSSSTLMKH-KIIHTG--EKPYKCEECGKAFRQSSHLTRH-KAIHTGEKP---------- 354
Query: 476 VYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQV 535
Y+C C + N + L+ H + H P + C C F S+L H
Sbjct: 355 -YKCEECGKAFNHFSDLRRH-KIIHTGKKP-------YKCEECGKAFSQSSTLRNH---- 401
Query: 536 HCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYI 595
++ T ++P Y C C + ++S L ++K I K
Sbjct: 402 -----------QIIHTGEKP----YKCEECGKAFKWSSKLTVHKVIHTGEKPCKCE---- 442
Query: 596 HNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKT 655
GK + S L + T K+ Y C +CG + + H
Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKL--------------YKCEECGKAFNNSSILAKHKII 488
Query: 656 HLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLD 715
H T C +C K F L +H IH Y CE C K F+ L++H +
Sbjct: 489 H--TGKKPYKCEECGKAFRQSSHLTRHKAIH--TGEKPYKCEECGKAFSHFSALRRHKII 544
Query: 716 MHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNH 775
++C C + F +++ H + H+ EK Y+C C F+ + L + H
Sbjct: 545 HTGKKPYKCEECGKAFSHFSALRRHKII-HTGEKP-YKCEECGKAFKWSSKLTV---HKV 599
Query: 776 LENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHC 833
+ K KC CG+SF L+ H I T K Y C+ C KAF++ L KH
Sbjct: 600 IHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTG 659
Query: 834 VFETKTPNCGT--NGASEQVQKEEVELQTLLTNSQE-----SHNSHDGSEEDVDTSEPMY 886
K CG +S+ + + +E H S + + T + Y
Sbjct: 660 EKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGKKPY 719
Query: 887 GCDICGAAYTMETLLQNHQLRDHNIRPGE------------SAIVKKKAELIKGNYKCNV 934
C+ CG A++ + L+ H++ +P + V K + KC
Sbjct: 720 KCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEE 779
Query: 935 CSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICK 994
C + F + LR+H H G K Y C CG+ F TL +HK+ H+ C C
Sbjct: 780 CGKAFKHFSALRKHKIIHTGK-KPYKCEECGKAFNDSSTLMKHKIIHT-GKKPYKCAECG 837
Query: 995 MPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQT 1054
+ H +H + ++C C + ++ LK H H +
Sbjct: 838 KAFKQSSHLTRHKAIHTGEK----PYKCEECGKDFNNSSTLKKHKLIHTR---------- 883
Query: 1055 TGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPGINVPP 1111
+KLYKC C+K F + L+K + PY C C K +S
Sbjct: 884 -------EKLYKCEECVKAFNNFSALMKHKIIHTGEKPY-KCEECGKAFKWSSK------ 929
Query: 1112 GTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNST 1171
L +++ + G +C C+ F+ S L+ H + IH
Sbjct: 930 ------LTEHKVI-------HTGEKPCKCEECDKAFKHFSALRKH-KVIH---------- 965
Query: 1172 QLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCS 1231
KK YQC +C F N + H H ++ ++C+ C
Sbjct: 966 ------------------TGKKPYQCDECGKAFNNSSTLTKHKIIHTGEK--PYKCEECG 1005
Query: 1232 QTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQC 1291
+ F + L H I HS E +KC C F Q++ L +H G +K Y C +C
Sbjct: 1006 KAFSQSSILTKHKIIHSVE---KPYKCEECGKAFNQSSHLTRHKTIHTG--EKPYKCEEC 1060
Query: 1292 PQKFFFQTELQNH 1304
+ F + L H
Sbjct: 1061 GKAFIQCSYLIRH 1073
Score = 249 bits (635), Expect = 2e-65
Identities = 265/1098 (24%), Positives = 401/1098 (36%), Gaps = 173/1098 (15%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E C+ C + F S++T+HK ++ G C S+ + H
Sbjct: 128 ETPFRCEECGKAFNQSSNLTDHK----RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTA 183
Query: 104 GCDFGEEEGGPGL-----------------PYPCQFCDKSFSRLSYLKHHEQSHSDKLPF 146
+ E+ G PY + C K+FS+ S L+ HE H+ + P+
Sbjct: 184 EKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPY 243
Query: 147 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAI 206
KC C + FK H +HTG+K Y C EC AFS+ LK H HT KPYKC
Sbjct: 244 KCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEE 303
Query: 207 CRRGFLSSSSLHGHMQVHERNKD--------GSQSGSRMEDWKMKDT----QKCSQCEEG 254
C + F SSS+L H +H K + S + K T KC +C +
Sbjct: 304 CGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKA 363
Query: 255 FDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSI 314
F+ DL++H H P +C C + F + ++L NH + +H+GEK C
Sbjct: 364 FNHFSDLRRHKI-IHTGKKP------YKCEECGKAFSQSSTLRNH-QIIHTGEKPYKCEE 415
Query: 315 CSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAA 374
C ++F +L H H + C + S+ + ++
Sbjct: 416 CGKAFKWSSKLTVHKVIHTGEKPCKCEECGK----AFKHFSA--------LRKHKVIHTR 463
Query: 375 PPIPKSRGRKRAAQQTPDMTGPSS-KQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKP 433
+ K +A + + K Y C C K F + L H K +H
Sbjct: 464 EKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKA-FRQSSHLTRH-KAIHTG-- 519
Query: 434 EQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQ 493
E+ + C+ C + L H K +H + P Y+C C + + + L+
Sbjct: 520 EKPYKCEECGKAFSHFSALRRH-KIIHTGKKP-----------YKCEECGKAFSHFSALR 567
Query: 494 EHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFGS 546
H + H P + C C F S L H + +H C+ G F
Sbjct: 568 RH-KIIHTGEKP-------YKCEECGKAFKWSSKLTVH-KVIHTAEKPCKCEECGKSF-K 617
Query: 547 PVLGTPKEPVV----EVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSR 602
K V+ ++Y C C + FNS L KH IH G+K
Sbjct: 618 HFSALRKHKVIHTREKLYKCEECVKA--FNSFSALMKH------------KVIHTGEKPY 663
Query: 603 ALSPLSPVAIEQTSLKMMQAV--GGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV 660
+ L + + + G P + C +CG + + + H H T
Sbjct: 664 KCEECGKAFKWSSKLTVHKVIHTGEKPCK------CEECGKAFKHFSALRKHKVIH--TG 715
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C +C K F SL KH IH Y CE C K F + L H +
Sbjct: 716 KKPYKCEECGKAFSQSSSLRKHEIIHS--GEKPYKCEECGKAFKWLSKLTVHKVIHTAEK 773
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
+C C + F +++ H + H+ KK Y+C C F + + L +KH +
Sbjct: 774 PCKCEECGKAFKHFSALRKHKII-HTG-KKPYKCEECGKAFNDSSTL---MKHKIIHTGK 828
Query: 781 KVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETK 838
K +KC CG++F L H H+ K Y C+ C K F+ L+KH K K
Sbjct: 829 KPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKH---KLIHTREK 885
Query: 839 TPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTME 898
C E+ K L+ + + + T E Y C+ CG A+
Sbjct: 886 LYKC------EECVKAFNNFSALMKH------------KIIHTGEKPYKCEECGKAFKWS 927
Query: 899 TLLQNHQLRDHNIRPGE-----------SAIVKKKA-ELIKGNYKCNVCSRTFFSENGLR 946
+ L H++ +P + SA+ K K K Y+C+ C + F + + L
Sbjct: 928 SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLT 987
Query: 947 EHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEH 1006
+H H G K Y C CG+ F LT+HK+ HS C C H
Sbjct: 988 KHKIIHTGE-KPYKCEECGKAFSQSSILTKHKIIHSVEKPY-KCEECGKAFNQSSHLTRH 1045
Query: 1007 CQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM-QKTGNGSAVQTTGRGQHV---- 1061
+H + ++C C + L H T H +K N V H
Sbjct: 1046 KTIHTGEKP----YKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK 1101
Query: 1062 -----QKLYKCASCLKEF 1074
+K YKC C K F
Sbjct: 1102 TIHTGEKPYKCEECAKAF 1119
Score = 192 bits (489), Expect = 1e-48
Identities = 228/948 (24%), Positives = 338/948 (35%), Gaps = 187/948 (19%)
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
K T+ CI C+K F L+ L H K +H+ + + C+ + S L +H K +H
Sbjct: 44 KKTFKCIKCSKSFF-MLSCLIRH-KRIHI--RQNIYKCEERGKAFKSFSTLTKH-KIIHT 98
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
P Y+ C +T +H R G F C C
Sbjct: 99 EDKP-----------YKYKKCGNAFKFSSTFTKHKRIHTG--------ETPFRCEECGKA 139
Query: 522 FLTDSSLEEHIRQVH-------CDLSGSRF-------GSPVLGTPKEPVVEVYSCSYCTN 567
F S+L +H +++H C+ G F V+ T ++P Y C C
Sbjct: 140 FNQSSNLTDH-KRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP----YKCEDCGK 194
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+ FN L KH IH GKK + ++L+ + +
Sbjct: 195 T--FNHFSALRKH------------KIIHTGKKPYKREECGKAFSQSSTLRKHEII---- 236
Query: 628 ARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTI 685
TGE Y C +CG + H H T C +C K F +L KH I
Sbjct: 237 --HTGEKPYKCEECGKAFKWSSKLTVHKVVH--TGEKPYKCEECGKAFSQFSTLKKHKII 292
Query: 686 HFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKH 745
H Y CE C K F S L KH + ++C C + F + H A+ H
Sbjct: 293 H--TGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAI-H 349
Query: 746 SNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--IT 803
+ EK Y+C C F + +DL+ +H + K +KC CG++F L+ H I
Sbjct: 350 TGEKP-YKCEECGKAFNHFSDLR---RHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIH 405
Query: 804 THSKKYNCKFCSKAF--------HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEE 855
T K Y C+ C KAF H +I H EK C K CG
Sbjct: 406 TGEKPYKCEECGKAFKWSSKLTVHKVI----HTGEKPC----KCEECG------------ 445
Query: 856 VELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGE 915
H S + + T E +Y C+ CG A+ ++L H++ +P
Sbjct: 446 ---------KAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKP-- 494
Query: 916 SAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLT 975
YKC C + F + L H H G K Y C CG+ F L
Sbjct: 495 --------------YKCEECGKAFRQSSHLTRHKAIHTGE-KPYKCEECGKAFSHFSALR 539
Query: 976 EHKVTHSKSLDTGNCRICKMPLQSEE-----EFLEHCQMHPDLRNSLTGFRCVVCMQTVT 1030
HK+ H TG K P + EE + H + ++C C +
Sbjct: 540 RHKIIH-----TG-----KKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFK 589
Query: 1031 STLELKIHGTFH-------MQKTGNGSAVQTTGRGQHV----QKLYKCASCLKEFRSKQD 1079
+ +L +H H ++ G + R V +KLYKC C+K F S
Sbjct: 590 WSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSA 649
Query: 1080 LVK---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGL 1136
L+K + PY C C K +S + G
Sbjct: 650 LMKHKVIHTGEKPY-KCEECGKAFKWSSK-------------------LTVHKVIHTGEK 689
Query: 1137 KTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQ 1196
+C C F+ S L+ H + IH P K S R +K Y+
Sbjct: 690 PCKCEECGKAFKHFSALRKH-KVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYK 748
Query: 1197 CIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTF 1256
C +C F + VH H ++ +C+ C + F + L+ H I H+ + +
Sbjct: 749 CEECGKAFKWLSKLTVHKVIHTAEKPC--KCEECGKAFKHFSALRKHKIIHTGK---KPY 803
Query: 1257 KCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
KC C F ++ L +H G+ K Y C +C + F + L H
Sbjct: 804 KCEECGKAFNDSSTLMKHKIIHTGK--KPYKCAECGKAFKQSSHLTRH 849
Score = 89.4 bits (220), Expect = 2e-17
Identities = 121/573 (21%), Positives = 195/573 (34%), Gaps = 109/573 (19%)
Query: 799 QCHITTHSKKYNCKFCSKAFH-----------------------AIILLEKHLREKHCVF 835
QC T K + C K FH + +L +R K
Sbjct: 11 QCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHI 70
Query: 836 ETKTPNCGTNGAS----------EQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPM 885
C G + + + E+ + + +S + + T E
Sbjct: 71 RQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETP 130
Query: 886 YGCDICGAAYTMETLLQNHQLRDHNIRPGESAI-VKKKAELIKGN--------------- 929
+ C+ CG A+ + L +H+ I GE ++ + KG+
Sbjct: 131 FRCEECGKAFNQSSNLTDHK----RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP 186
Query: 930 YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN 989
YKC C +TF + LR+H H G K Y CG+ F TL +H++ H+
Sbjct: 187 YKCEDCGKTFNHFSALRKHKIIHTGK-KPYKREECGKAFSQSSTLRKHEIIHTGE-KPYK 244
Query: 990 CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNG 1049
C C + + H +H + ++C C + + LK H H K
Sbjct: 245 CEECGKAFKWSSKLTVHKVVHTGEK----PYKCEECGKAFSQFSTLKKHKIIHTGK---- 296
Query: 1050 SAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAGCVNLSKSASPG 1106
K YKC C K F S L+K + PY C C + +S
Sbjct: 297 -------------KPYKCEECGKAFNSSSTLMKHKIIHTGEKPY-KCEECGKAFRQSS-- 340
Query: 1107 INVPPGTNRPGLGQNENLSAIEGKGK---------------VGGLKTRCSSCNVKFESES 1151
T + E E GK G +C C F S
Sbjct: 341 ----HLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSS 396
Query: 1152 ELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQ 1211
L+NH Q IH P K + S + +K +C +C F + ++
Sbjct: 397 TLRNH-QIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALR 455
Query: 1212 VHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1271
H H ++ ++C+ C + F++ + L H I H+ + +KC C F Q++ L
Sbjct: 456 KHKVIHTREK--LYKCEECGKAFNNSSILAKHKIIHTGK---KPYKCEECGKAFRQSSHL 510
Query: 1272 QQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+H A +K Y C +C + F + L+ H
Sbjct: 511 TRH--KAIHTGEKPYKCEECGKAFSHFSALRRH 541
>gi|210031219 zinc finger protein 845 [Homo sapiens]
Length = 970
Score = 239 bits (610), Expect = 1e-62
Identities = 223/888 (25%), Positives = 335/888 (37%), Gaps = 187/888 (21%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C C K F++ YL H + H+ K P+KC C + F + + H +LHTG+K Y CS
Sbjct: 243 YKCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCS 302
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
EC FSR+ L IH HT K YKC C + F +S L H ++H K
Sbjct: 303 ECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRLHTGEK--------- 353
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
KC +C++ F F +L++H + H P +C C F ++SL
Sbjct: 354 -------PYKCEECDKAFSFKSNLERH-RKIHTGEKP------YKCNECSRTFSRKSSLT 399
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
H ++H+GEK C+ C ++F + L H H ++P C +
Sbjct: 400 RH-RRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKCEECD------------E 446
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLF 415
+ + SNL R R+ + P Y C C K F
Sbjct: 447 AFSFKSNL----------------ERHRRIHTGEKP-------------YKCNDCGK-TF 476
Query: 416 SSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAI 475
S + L H + L E+ + C+ C E NL H + +H +
Sbjct: 477 SQTSSLVYHRR---LHTGEKPYKCEECDEAFSFKSNLERH-RIIHTGEK----------- 521
Query: 476 VYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQV 535
+Y+CN C + + ++L H R G + C C F S+L H + +
Sbjct: 522 LYKCNECGKTFSRKSSLTRHCRLHTG--------EKPYQCNECGKAFRGQSALIYH-QAI 572
Query: 536 HCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALN-- 593
H + ++Y C+ C +F++ + H + +++ N
Sbjct: 573 H------------------GIGKLYKCNDC--HQVFSNATTIANHWRIHNEERSYKCNRC 612
Query: 594 --------YI------HNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICN 637
Y+ H+G+K +++L+ + + TGE Y CN
Sbjct: 613 GKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRI------HTGEKPYRCN 666
Query: 638 QCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICE 697
+CG ++ H + H T C +C K F +L+ H IH Y C
Sbjct: 667 ECGKTFSRKSYLTCHRRLH--TGEKPYKCNECGKTFGRNSALIIHKAIH--TGEKPYKCN 722
Query: 698 SCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTS 756
C K F+ L H L +HT ++C C +VF K S++ H + H+ EK Y+C
Sbjct: 723 ECGKAFSQKSSLTCH-LRLHTGEKPYKCEECDKVFSRKSSLEKHRRI-HTGEKP-YKCKV 779
Query: 757 CNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFC 814
C+ F ++ L +H + K +KC CG++F L H HS K Y C C
Sbjct: 780 CDKAFGRDSHL---AQHTRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNEC 836
Query: 815 SKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDG 874
K F LE H K CG ++ N H H
Sbjct: 837 GKTFRHNSALEIHKAIHTGEKPYKCSECG-------------KVFNRKANLSRHHRLH-- 881
Query: 875 SEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNV 934
T E Y C+ CG + + L H H I GE YKCN
Sbjct: 882 ------TGEKPYKCNKCGKVFNQQAHLACH----HRIHTGEKP------------YKCNE 919
Query: 935 CSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHS 982
C +TF + L H H G K Y C CG+ F L H H+
Sbjct: 920 CGKTFRHNSVLVIHKTIHTGE-KPYKCNECGKVFNRKAKLARHHRIHT 966
Score = 233 bits (593), Expect = 1e-60
Identities = 207/803 (25%), Positives = 307/803 (38%), Gaps = 166/803 (20%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C C K+FS+ SYL +H + H+ + P+KC C + F K + +RH K+HTG+K Y C+
Sbjct: 327 YKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCN 386
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
EC FSR L H + HT KPYKC C + F SSL H ++H K
Sbjct: 387 ECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEK--------- 437
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
KC +C+E F F +L++H H P +C C + F + +SL+
Sbjct: 438 -------PYKCEECDEAFSFKSNLERH-RRIHTGEKP------YKCNDCGKTFSQTSSLV 483
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
H ++H+GEK C C E+F L H H ++ CN ++ S
Sbjct: 484 YH-RRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKT------FSRKS 536
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLF 415
S T L P + K Q+ + + Y C C+ Q+F
Sbjct: 537 SLTRHCRLHTGEK-------PYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCH-QVF 588
Query: 416 SSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAI 475
S+ + H + + E+++ C C + L H + H + P
Sbjct: 589 SNATTIANHWR---IHNEERSYKCNRCGKFFRHRSYLAVHWR-THSGEKP---------- 634
Query: 476 VYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQV 535
Y+C C E + + LQ H R G + C C F S L H R
Sbjct: 635 -YKCEECDEAFSFKSNLQRHRRIHTG--------EKPYRCNECGKTFSRKSYLTCHRR-- 683
Query: 536 HCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYI 595
L T ++P Y C+ C + NS L ++K I
Sbjct: 684 -------------LHTGEKP----YKCNECGKTFGRNSALIIHK--------------AI 712
Query: 596 HNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKT 655
H G+K Y CN+CG ++ S HL+
Sbjct: 713 HTGEK--------------------------------PYKCNECGKAFSQKSSLTCHLRL 740
Query: 656 HLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLD 715
H T C +C+K F + SL KH IH Y C+ CDK F L +H
Sbjct: 741 H--TGEKPYKCEECDKVFSRKSSLEKHRRIH--TGEKPYKCKVCDKAFGRDSHLAQHTRI 796
Query: 716 MHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNH 775
++C C + F ++ +H A+ HS EK Y+C C FR+ + L++ H
Sbjct: 797 HTGEKPYKCNECGKNFRHNSALVIHKAI-HSGEKP-YKCNECGKTFRHNSALEI---HKA 851
Query: 776 LENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHC 833
+ K +KC CG+ F + L H H+ K Y C C K F+ + HL H
Sbjct: 852 IHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQ----QAHLACHHR 907
Query: 834 VFETKTP-NCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICG 892
+ + P C G + + HNS + + T E Y C+ CG
Sbjct: 908 IHTGEKPYKCNECGKTFR------------------HNSVLVIHKTIHTGEKPYKCNECG 949
Query: 893 AAYTMETLLQNHQLRDHNIRPGE 915
+ + L H H I G+
Sbjct: 950 KVFNRKAKLARH----HRIHTGK 968
Score = 230 bits (586), Expect = 8e-60
Identities = 226/961 (23%), Positives = 349/961 (36%), Gaps = 199/961 (20%)
Query: 126 SFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSR 185
+F S L ++ H + F+C + F + +H +H G K+Y C C F++
Sbjct: 195 NFLNSSLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQ 254
Query: 186 SDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDT 245
+L H + HT KPYKC C + F +L H ++H K
Sbjct: 255 KRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKH---------------- 298
Query: 246 QKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHS 305
KCS+C + F L H A + + +C C + F +TS + + ++H+
Sbjct: 299 YKCSECGKTFSRNSALVIHKA-------IHTGEKSYKCNECGKTF-SQTSYLVYHRRLHT 350
Query: 306 GEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNL 363
GEK C C ++F L H H ++P CN + ++ SS T
Sbjct: 351 GEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRT------FSRKSSLT----- 399
Query: 364 SVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQI 423
R R+ + P Y C C K FS ++ L
Sbjct: 400 -----------------RHRRLHTGEKP-------------YKCNDCGK-TFSQMSSLVY 428
Query: 424 HLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCS 483
H + L E+ + C+ C E NL H +++H + P Y+CN C
Sbjct: 429 HRR---LHTGEKPYKCEECDEAFSFKSNLERH-RRIHTGEKP-----------YKCNDCG 473
Query: 484 EVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSR 543
+ + ++L H R G + C C F S+LE H R +H +G +
Sbjct: 474 KTFSQTSSLVYHRRLHTG--------EKPYKCEECDEAFSFKSNLERH-RIIH---TGEK 521
Query: 544 FGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRA 603
+Y C+ C + F+ L +H + +H G+K
Sbjct: 522 ---------------LYKCNECGKT--FSRKSSLTRHCR------------LHTGEKPYQ 552
Query: 604 LSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPK 663
+ Q++L QA+ G Y CN C +++ + H + H + K
Sbjct: 553 CNECGKAFRGQSALIYHQAIHGIGKL----YKCNDCHQVFSNATTIANHWRIHNEERSYK 608
Query: 664 LTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFR 723
C +C K F ++ L H H Y CE CD+ F+ +LQ+H +R
Sbjct: 609 --CNRCGKFFRHRSYLAVHWRTH--SGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYR 664
Query: 724 CTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVH 783
C C + F K + H + H+ EK Y+C C F + L + H + K +
Sbjct: 665 CNECGKTFSRKSYLTCHRRL-HTGEKP-YKCNECGKTFGRNSAL---IIHKAIHTGEKPY 719
Query: 784 KCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPN 841
KC CG++F + L CH+ H+ K Y C+ C K F LEKH R
Sbjct: 720 KCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRR------------ 767
Query: 842 CGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLL 901
+ E + + + +SH + T E Y C+ CG
Sbjct: 768 ---------IHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECG--------- 809
Query: 902 QNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMC 961
N R + ++ K + YKCN C +TF + L H H G K Y C
Sbjct: 810 -------KNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGE-KPYKC 861
Query: 962 PICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFR 1021
CG+ F L+ H H+ C C + H H + ++
Sbjct: 862 SECGKVFNRKANLSRHHRLHTGE-KPYKCNKCGKVFNQQ----AHLACHHRIHTGEKPYK 916
Query: 1022 CVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV 1081
C C +T L IH T H TG +K YKC C K F K L
Sbjct: 917 CNECGKTFRHNSVLVIHKTIH---TG--------------EKPYKCNECGKVFNRKAKLA 959
Query: 1082 K 1082
+
Sbjct: 960 R 960
Score = 219 bits (559), Expect = 1e-56
Identities = 212/848 (25%), Positives = 317/848 (37%), Gaps = 160/848 (18%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS+ L H + H+ + +KC+ C + F + H +HTG+K Y C
Sbjct: 270 PYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKC 329
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+EC FS++ +L H + HT KPYKC C + F S+L H ++H K
Sbjct: 330 NECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEK-------- 381
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
KC++C F L +H H P +C C + F + +SL
Sbjct: 382 --------PYKCNECSRTFSRKSSLTRH-RRLHTGEKP------YKCNDCGKTFSQMSSL 426
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSV 354
+ H ++H+GEK C C E+F L H H ++P CN ++
Sbjct: 427 VYH-RRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKT------FSQT 479
Query: 355 SSTTPDSNLSVDSSTM----VEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYC 410
SS L + A + R R TG + Y C C
Sbjct: 480 SSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIH-----TG------EKLYKCNEC 528
Query: 411 NKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVS 470
K FS + L H + +KP Q C C + L H + +H
Sbjct: 529 GK-TFSRKSSLTRHCRLHTGEKPYQ---CNECGKAFRGQSALIYH-QAIHGI-------- 575
Query: 471 AMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEE 530
+Y+CN C +V ++ T+ H R + + ++ C C F S L
Sbjct: 576 ---GKLYKCNDCHQVFSNATTIANHWRIHN--------EERSYKCNRCGKFFRHRSYLAV 624
Query: 531 HIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPL 590
H R H SG + Y C C + F S L+ ++
Sbjct: 625 HWR-TH---SGEK---------------PYKCEECDEAFSFKSNLQRHRR---------- 655
Query: 591 ALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDS 648
IH G+K + ++ L + + TGE Y CN+CG + +
Sbjct: 656 ----IHTGEKPYRCNECGKTFSRKSYLTCHRRL------HTGEKPYKCNECGKTFGRNSA 705
Query: 649 FQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDD 708
H H T C +C K F + SL H+ +H Y CE CDK F+
Sbjct: 706 LIIHKAIH--TGEKPYKCNECGKAFSQKSSLTCHLRLH--TGEKPYKCEECDKVFSRKSS 761
Query: 709 LQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQ 768
L+KH ++C +C + F + H + H+ EK Y+C C +FR+ + L
Sbjct: 762 LEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRI-HTGEKP-YKCNECGKNFRHNSAL- 818
Query: 769 LHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEK 826
V H + + K +KC CG++F L+ H I T K Y C C K F+ L +
Sbjct: 819 --VIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSR 876
Query: 827 HLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMY 886
H R K CG + N Q +H + T E Y
Sbjct: 877 HHRLHTGEKPYKCNKCGK-----------------VFNQQ----AHLACHHRIHTGEKPY 915
Query: 887 GCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLR 946
C+ CG + ++L H+ I GE YKCN C + F + L
Sbjct: 916 KCNECGKTFRHNSVLVIHK----TIHTGEKP------------YKCNECGKVFNRKAKLA 959
Query: 947 EHMQTHLG 954
H + H G
Sbjct: 960 RHHRIHTG 967
Score = 192 bits (489), Expect = 1e-48
Identities = 178/711 (25%), Positives = 277/711 (38%), Gaps = 138/711 (19%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C+ CDK+FS S L+ H + H+ + P+KC CSR F K S RH +LHTG+K Y C
Sbjct: 354 PYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKC 413
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERN 227
++C FS+ L H + HT KPYKC C F S+L H ++H +
Sbjct: 414 NDCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCG 473
Query: 228 KDGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKH--------IAECHPECSPNE 276
K SQ+ S + ++ + KC +C+E F F +L++H + +C+ EC
Sbjct: 474 KTFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCN-ECGKTF 532
Query: 277 DRAA--------------LQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTV 322
R + QC C + F +++L+ H + +H K C+ C + F
Sbjct: 533 SRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYH-QAIHGIGKLYKCNDCHQVFSNA 591
Query: 323 EELYSHMDSHQQPES--CNHSNS----PSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPP 376
+ +H H + S CN S + V + + S P D + ++
Sbjct: 592 TTIANHWRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKS--- 648
Query: 377 IPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQA 436
R R+ + P Y C C K FS + L H + L E+
Sbjct: 649 -NLQRHRRIHTGEKP-------------YRCNECGK-TFSRKSYLTCHRR---LHTGEKP 690
Query: 437 HICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHI 496
+ C C + L H K +H + P Y+CN C + + ++L H+
Sbjct: 691 YKCNECGKTFGRNSALIIH-KAIHTGEKP-----------YKCNECGKAFSQKSSLTCHL 738
Query: 497 RCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPV 556
R G + C C F SSLE+H R++H T ++P
Sbjct: 739 RLHTG--------EKPYKCEECDKVFSRKSSLEKH-RRIH--------------TGEKP- 774
Query: 557 VEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTS 616
Y C C + F L +H + IH G+K + ++
Sbjct: 775 ---YKCKVCDKA--FGRDSHLAQHTR------------IHTGEKPYKCNECGKNFRHNSA 817
Query: 617 LKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQ 676
L + +A+ Y CN+CG + + + H H T C +C K F +
Sbjct: 818 LVIHKAIHSGEK----PYKCNECGKTFRHNSALEIHKAIH--TGEKPYKCSECGKVFNRK 871
Query: 677 ESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF----FRCTLCQEVFD 732
+L +H +H Y C C K F Q HL H ++C C + F
Sbjct: 872 ANLSRHHRLH--TGEKPYKCNKCGKVFNQ----QAHLACHHRIHTGEKPYKCNECGKTFR 925
Query: 733 SKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVH 783
+ +H + H+ EK Y+C C F + L H H + GK H
Sbjct: 926 HNSVLVIHKTI-HTGEKP-YKCNECGKVFNRKAKLARH----HRIHTGKKH 970
Score = 169 bits (429), Expect = 1e-41
Identities = 195/856 (22%), Positives = 307/856 (35%), Gaps = 165/856 (19%)
Query: 477 YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSL-------- 528
Y+C+ C +V N L H RC G + C C F + +L
Sbjct: 243 YKCDVCGKVFNQKRYLACHRRCHTG--------KKPYKCNDCGKTFSQELTLTCHHRLHT 294
Query: 529 -EEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKN 587
E+H + C + SR + V+ + Y C+ C + S L ++ +
Sbjct: 295 GEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRL------ 348
Query: 588 IPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTS 645
H G+K +++L+ + + TGE Y CN+C ++
Sbjct: 349 --------HTGEKPYKCEECDKAFSFKSNLERHRKIH------TGEKPYKCNECSRTFSR 394
Query: 646 LDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTS 705
S H + H T C C K F SL+ H +H Y CE CD+ F+
Sbjct: 395 KSSLTRHRRLH--TGEKPYKCNDCGKTFSQMSSLVYHRRLH--TGEKPYKCEECDEAFSF 450
Query: 706 VDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNET 765
+L++H ++C C + F S+ H + H+ EK Y+C C+ F ++
Sbjct: 451 KSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRL-HTGEKP-YKCEECDEAFSFKS 508
Query: 766 DLQLHVKHNHLENQGKVHKCIFCGESFGTEVEL--QCHITTHSKKYNCKFCSKAFHAIIL 823
+L+ +H + K++KC CG++F + L C + T K Y C C KAF
Sbjct: 509 NLE---RHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSA 565
Query: 824 LEKH-----------LREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSH 872
L H + H VF T T ++ EE + H S+
Sbjct: 566 LIYHQAIHGIGKLYKCNDCHQVFSNAT----TIANHWRIHNEERSYKCNRCGKFFRHRSY 621
Query: 873 DGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKC 932
+ E Y C+ C A++ ++ LQ H+ I GE Y+C
Sbjct: 622 LAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHR----RIHTGEKP------------YRC 665
Query: 933 NVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRI 992
N C +TF ++ L H + H G K Y C CG+ F L HK H+ C
Sbjct: 666 NECGKTFSRKSYLTCHRRLHTGE-KPYKCNECGKTFGRNSALIIHKAIHTGEKPY-KCNE 723
Query: 993 CKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAV 1052
C + H ++H + ++C C + + L+ H H
Sbjct: 724 CGKAFSQKSSLTCHLRLHTGEKP----YKCEECDKVFSRKSSLEKHRRIH---------- 769
Query: 1053 QTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINV 1109
TG +K YKC C K F L ++ PY C C
Sbjct: 770 --TG-----EKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYK-CNEC------------- 808
Query: 1110 PPGTNRPGLGQNENLSAIEGKGKVGGLKT-RCSSCNVKFESESELQNHIQTIHRELVPDS 1168
G N + + K G K +C+ C F S L+ H + IH
Sbjct: 809 -------GKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIH-KAIHTG----- 855
Query: 1169 NSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECK 1228
+K Y+C +C VF + ++ H H ++ ++C
Sbjct: 856 -----------------------EKPYKCSECGKVFNRKANLSRHHRLHTGEKP--YKCN 890
Query: 1229 LCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDC 1288
C + F+ A L CH H+ E +KC C F + L H G +K Y C
Sbjct: 891 KCGKVFNQQAHLACHHRIHTGE---KPYKCNECGKTFRHNSVLVIHKTIHTG--EKPYKC 945
Query: 1289 TQCPQKFFFQTELQNH 1304
+C + F + +L H
Sbjct: 946 NECGKVFNRKAKLARH 961
Score = 168 bits (426), Expect = 3e-41
Identities = 208/891 (23%), Positives = 327/891 (36%), Gaps = 193/891 (21%)
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHIC--QYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K +F+ L H + KP + + C + E+ + ++ ++ ++
Sbjct: 243 YKCDVCGK-VFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKC 301
Query: 463 QDPGLIVSAMPAIV-----------YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSN 511
+ G S A+V Y+CN C + + + L H R G
Sbjct: 302 SECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRLHTG--------EK 353
Query: 512 AFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIF 571
+ C C F S+LE H R++H T ++P Y C+ C+ + F
Sbjct: 354 PYKCEECDKAFSFKSNLERH-RKIH--------------TGEKP----YKCNECSRT--F 392
Query: 572 NSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPT 631
+ L +H + +H G+K + + +SL + + T
Sbjct: 393 SRKSSLTRHRR------------LHTGEKPYKCNDCGKTFSQMSSLVYHRRLH------T 434
Query: 632 GE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMI 689
GE Y C +C ++ + + H + H T C C K F SL+ H +H
Sbjct: 435 GEKPYKCEECDEAFSFKSNLERHRRIH--TGEKPYKCNDCGKTFSQTSSLVYHRRLH--T 490
Query: 690 TSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEK 749
Y CE CD+ F+ +L++H + ++C C + F K S+ H + H+ EK
Sbjct: 491 GEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRL-HTGEK 549
Query: 750 KVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--K 807
Y+C C FR ++ L + H + GK++KC C + F + H H+ +
Sbjct: 550 P-YQCNECGKAFRGQSAL---IYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRIHNEER 605
Query: 808 KYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQE 867
Y C C K F L H R T+ + + EE + ++ +
Sbjct: 606 SYKCNRCGKFFRHRSYLAVHWR--------------THSGEKPYKCEECDEAFSFKSNLQ 651
Query: 868 SHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIK 927
H + T E Y C+ CG ++ ++ L H+ + GE
Sbjct: 652 RHRR-------IHTGEKPYRCNECGKTFSRKSYLTCHR----RLHTGEKP---------- 690
Query: 928 GNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDT 987
YKCN C +TF + L H H G K Y C CG+ F +LT H H+
Sbjct: 691 --YKCNECGKTFGRNSALIIHKAIHTGE-KPYKCNECGKAFSQKSSLTCHLRLHTGE-KP 746
Query: 988 GNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTG 1047
C C + +H ++H + ++C VC + L H H TG
Sbjct: 747 YKCEECDKVFSRKSSLEKHRRIHTGEK----PYKCKVCDKAFGRDSHLAQHTRIH---TG 799
Query: 1048 NGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGI 1107
+K YKC C K FR LV + K+ G
Sbjct: 800 --------------EKPYKCNECGKNFRHNSALV-----------------IHKAIHSG- 827
Query: 1108 NVPPGTNRPGLGQNENLSAIEGKGKV--GGLKTRCSSCNVKFESESELQNHIQTIHRELV 1165
P N G N SA+E + G +CS C F ++ L H HR
Sbjct: 828 EKPYKCNECGKTFRHN-SALEIHKAIHTGEKPYKCSECGKVFNRKANLSRH----HR--- 879
Query: 1166 PDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVA-NHMIDEGLN 1224
L T + K Y+C KC VF + Q H+A +H I G
Sbjct: 880 -------LHTGE---------------KPYKCNKCGKVF----NQQAHLACHHRIHTGEK 913
Query: 1225 -HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1274
++C C +TF + L H H+ E +KC C VF + KL +H
Sbjct: 914 PYKCNECGKTFRHNSVLVIHKTIHTGE---KPYKCNECGKVFNRKAKLARH 961
Score = 157 bits (398), Expect = 5e-38
Identities = 161/662 (24%), Positives = 249/662 (37%), Gaps = 151/662 (22%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F S++ H+ ++ G C S SS H
Sbjct: 436 EKPYKCEECDEAFSFKSNLERHR----RIHTGEKPYKCNDCGKTFSQTSSLVYHRRLHT- 490
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C+ CD++FS S L+ H H+ + +KC C + F K S R
Sbjct: 491 ----GEK------PYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTR 540
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H +LHTG+K Y C+EC AF L H H K YKC C + F +++++ H ++
Sbjct: 541 HCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRI 600
Query: 224 H--ERNKDGSQSGSRME-------DWKMKDTQ---KCSQCEEGFDFPEDLQKHIAECHPE 271
H ER+ ++ G W+ + KC +C+E F F +LQ+H H
Sbjct: 601 HNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRH-RRIHTG 659
Query: 272 CSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDS 331
P +C C + F ++ L H ++H+GEK C+ C ++F L H
Sbjct: 660 EKP------YRCNECGKTFSRKSYLTCH-RRLHTGEKPYKCNECGKTFGRNSALIIHKAI 712
Query: 332 H--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQ 389
H ++P CN ++ SS T L G K
Sbjct: 713 HTGEKPYKCNECGK------AFSQKSSLTCHLRLHT----------------GEK----- 745
Query: 390 TPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSL 449
Y C C+K +FS + L+ H + +KP + +C
Sbjct: 746 --------------PYKCEECDK-VFSRKSSLEKHRRIHTGEKPYKCKVCD-------KA 783
Query: 450 YNLNEHLKQ---VHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPA 506
+ + HL Q +H + P Y+CN C + + L H + H P
Sbjct: 784 FGRDSHLAQHTRIHTGEKP-----------YKCNECGKNFRHNSALVIH-KAIHSGEKP- 830
Query: 507 AKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCT 566
+ C C F +S+LE H + +H T ++P Y CS C
Sbjct: 831 ------YKCNECGKTFRHNSALEIH-KAIH--------------TGEKP----YKCSEC- 864
Query: 567 NSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGA 626
+FN L++H + +H G+K + V +Q L +
Sbjct: 865 -GKVFNRKANLSRH------------HRLHTGEKPYKCNKCGKVFNQQAHLACHHRI--- 908
Query: 627 PARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVT 684
TGE Y CN+CG + H H T C +C K F + L +H
Sbjct: 909 ---HTGEKPYKCNECGKTFRHNSVLVIHKTIH--TGEKPYKCNECGKVFNRKAKLARHHR 963
Query: 685 IH 686
IH
Sbjct: 964 IH 965
Score = 155 bits (392), Expect = 2e-37
Identities = 161/684 (23%), Positives = 246/684 (35%), Gaps = 120/684 (17%)
Query: 636 CNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYI 695
CN+ G + + H HL K C C K F + L H H Y
Sbjct: 217 CNESGKAFNYSSVLRKHQIIHLGAKQYK--CDVCGKVFNQKRYLACHRRCH--TGKKPYK 272
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFV-FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRC 754
C C K F+ L H +HT ++C+ C + F ++ +H A+ H+ EK Y+C
Sbjct: 273 CNDCGKTFSQELTLTCHHR-LHTGEKHYKCSECGKTFSRNSALVIHKAI-HTGEKS-YKC 329
Query: 755 TSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCK 812
C F + L V H L K +KC C ++F + L+ H I T K Y C
Sbjct: 330 NECGKTFSQTSYL---VYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCN 386
Query: 813 FCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSH 872
CS+ F L +H R K +CG K ++ +L+ + +
Sbjct: 387 ECSRTFSRKSSLTRHRRLHTGEKPYKCNDCG---------KTFSQMSSLVYHRR------ 431
Query: 873 DGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKC 932
+ T E Y C+ C A++ ++ L+ H+ I GE YKC
Sbjct: 432 ------LHTGEKPYKCEECDEAFSFKSNLERHR----RIHTGEKP------------YKC 469
Query: 933 NVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRI 992
N C +TF + L H + H G K Y C C E F L H++ H+ C
Sbjct: 470 NDCGKTFSQTSSLVYHRRLHTGE-KPYKCEECDEAFSFKSNLERHRIIHTGE-KLYKCNE 527
Query: 993 CKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFH---------- 1042
C + HC++H + ++C C + L H H
Sbjct: 528 CGKTFSRKSSLTRHCRLHTGEKP----YQCNECGKAFRGQSALIYHQAIHGIGKLYKCND 583
Query: 1043 -MQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSK 1101
Q N + + R + ++ YKC C K FR + L
Sbjct: 584 CHQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYL--------------------- 622
Query: 1102 SASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIH 1161
A+ + G +C C+ F +S LQ H + IH
Sbjct: 623 ------------------------AVHWRTHSGEKPYKCEECDEAFSFKSNLQRH-RRIH 657
Query: 1162 RELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDE 1221
P + KT +K Y+C +C F + +H A H ++
Sbjct: 658 TGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEK 717
Query: 1222 GLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQ 1281
++C C + F + L CHL H+ E +KC C VF + + L++H G
Sbjct: 718 P--YKCNECGKAFSQKSSLTCHLRLHTGE---KPYKCEECDKVFSRKSSLEKHRRIHTG- 771
Query: 1282 EDKIYDCTQCPQKFFFQTELQNHT 1305
+K Y C C + F + L HT
Sbjct: 772 -EKPYKCKVCDKAFGRDSHLAQHT 794
Score = 109 bits (273), Expect = 2e-23
Identities = 78/281 (27%), Positives = 118/281 (41%), Gaps = 44/281 (15%)
Query: 28 ALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWP 87
+L C R GE+ + C+ C +VF S + +H+ ++ G C
Sbjct: 733 SLTCHLRLHTGEK-----PYKCEECDKVFSRKSSLEKHR----RIHTGEKPYKCKVCDKA 783
Query: 88 ASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFK 147
S Q + H GE+ PY C C K+F S L H+ HS + P+K
Sbjct: 784 FGRDSHLAQHTRIHT-----GEK------PYKCNECGKNFRHNSALVIHKAIHSGEKPYK 832
Query: 148 CTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAIC 207
C C + F+H + + H +HTG+K Y CSEC F+R +L H + HT KPYKC C
Sbjct: 833 CNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKC 892
Query: 208 RRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAE 267
+ F + L H ++H K KC++C + F L H
Sbjct: 893 GKVFNQQAHLACHHRIHTGEK----------------PYKCNECGKTFRHNSVLVIH-KT 935
Query: 268 CHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEK 308
H P +C C ++F + L H ++H+G+K
Sbjct: 936 IHTGEKP------YKCNECGKVFNRKAKLARH-HRIHTGKK 969
Score = 87.4 bits (215), Expect = 8e-17
Identities = 91/388 (23%), Positives = 148/388 (38%), Gaps = 54/388 (13%)
Query: 920 KKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKV 979
K++ + + +++CN + F + LR+H HLG K Y C +CG+ F L H+
Sbjct: 205 KQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLG-AKQYKCDVCGKVFNQKRYLACHRR 263
Query: 980 THSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHG 1039
H+ C C E H ++H ++ ++C C +T + L IH
Sbjct: 264 CHT-GKKPYKCNDCGKTFSQELTLTCHHRLHTGEKH----YKCSECGKTFSRNSALVIHK 318
Query: 1040 TFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGC 1096
H TG +K YKC C K F LV +L PY C
Sbjct: 319 AIH---TG--------------EKSYKCNECGKTFSQTSYLVYHRRLHTGEKPY----KC 357
Query: 1097 VNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNH 1156
K+ S N+ K G +C+ C+ F +S L H
Sbjct: 358 EECDKAFSFKSNLER----------------HRKIHTGEKPYKCNECSRTFSRKSSLTRH 401
Query: 1157 IQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVAN 1216
+ E N Q+S + + E K Y+C +C F + +++ H
Sbjct: 402 RRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGE-KPYKCEECDEAFSFKSNLERHRRI 460
Query: 1217 HMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIF 1276
H ++ ++C C +TF + L H H+ E +KC C F + L++H
Sbjct: 461 HTGEK--PYKCNDCGKTFSQTSSLVYHRRLHTGE---KPYKCEECDEAFSFKSNLERHRI 515
Query: 1277 SAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
G +K+Y C +C + F ++ L H
Sbjct: 516 IHTG--EKLYKCNECGKTFSRKSSLTRH 541
>gi|119120877 zinc finger protein 721 [Homo sapiens]
Length = 923
Score = 228 bits (581), Expect = 3e-59
Identities = 220/923 (23%), Positives = 340/923 (36%), Gaps = 173/923 (18%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+ C C KSF + S L H+ H+ + P+ C + F ++H K+HTG+K Y C
Sbjct: 109 FKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCE 168
Query: 178 ECDAAFSRSDHLKIH----------------------------LKTHTSNKPYKCAICRR 209
EC AF+RS +L H K HT +KPYKC C +
Sbjct: 169 ECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGK 228
Query: 210 GFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECH 269
F+ SS L+ H ++H K KC +C + KH H
Sbjct: 229 AFMHSSHLNKHEKIHTGEK----------------PYKCKECGKVISSSSSFAKH-KRIH 271
Query: 270 PECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHM 329
P +C+ C + F T+L H ++H+GEK +C +C ++F LY H
Sbjct: 272 TGEKP------FKCLECGKAFNISTTLTKH-RRIHTGEKPYTCEVCGKAFRQSANLYVHR 324
Query: 330 DSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAA 387
H ++P +C G T S + + + K+ GR A
Sbjct: 325 RIHTGEKPYTCGE--------CGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTAL 376
Query: 388 QQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLP 447
Q + + Y C C K F+S L H + +KP + C+
Sbjct: 377 NQHKKI-----HTGEKPYKCEECGK-AFNSSTNLTAHKRIHTREKP---YTCEDRGRAFG 427
Query: 448 SLYNLNEHLKQVHEAQDPGLIVSAMPAIV-----------------YQCNFCSEVVNDLN 490
NLNE+ K++H P A + Y+C C +V+ +
Sbjct: 428 LSTNLNEY-KKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSS 486
Query: 491 TLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLG 550
+ +H R G F C C F + ++L +H R++H
Sbjct: 487 SFAKHKRIHTG--------EKPFECLECGKAFTSSTTLTKH-RRIH-------------- 523
Query: 551 TPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPV 610
T ++P Y+C C + +++L +++ IH G+K
Sbjct: 524 TGEKP----YTCEVCGKAFRQSAILYVHRR--------------IHTGEKPYTCEECGKT 565
Query: 611 AIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQ 668
+ +L + + + TGE Y C +CG + H K H L K C +
Sbjct: 566 FRQSANLYVHRRI------HTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYK--CEE 617
Query: 669 CNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQ 728
C K+F L + I+ Y CE C K F DL +H + ++C C
Sbjct: 618 CGKDFVWYTDLNQQKKIY--TGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECG 675
Query: 729 EVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFC 788
+ F +++ H + H+ EK Y+C C F +L H + + K +KC
Sbjct: 676 KAFGWSIALNQHKKI-HTGEKP-YKCEECGKAFSRSRNL---TTHRRVHTREKPYKCEDR 730
Query: 789 GESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG--- 843
G SFG L + I T K Y CK C K F L +H + K CG
Sbjct: 731 GRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVI 790
Query: 844 TNGAS----EQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMET 899
T+ +S +++ E + L + ++ + T E Y C+ CG A+
Sbjct: 791 TSSSSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSA 850
Query: 900 LLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHY 959
+L H+ I GE Y C C +TF L H + H G K Y
Sbjct: 851 ILYVHR----RIHTGEKP------------YTCGECGKTFRQSANLYAHKKIHTGE-KPY 893
Query: 960 MCPICGERFPSLLTLTEHKVTHS 982
C CG+ F L HK H+
Sbjct: 894 TCGDCGKTFRQSANLYAHKKIHT 916
Score = 222 bits (565), Expect = 2e-57
Identities = 227/953 (23%), Positives = 349/953 (36%), Gaps = 193/953 (20%)
Query: 49 CDSCLQVFESLSDITEHKINQCQLTDGVDVEDDP-TCSWPASSPSSKD---QTSPSHGEG 104
C+ C + F+ SD+T+HK G+ + P TC KD T + +
Sbjct: 111 CNECGKSFQKFSDLTQHK--------GIHAGEKPYTCE-----ERGKDFGWYTDLNQHKK 157
Query: 105 CDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRH 164
GE+ PY C+ C K+F+R + L H++ H+ + + R F + + +
Sbjct: 158 IHTGEK------PYKCEECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEY 211
Query: 165 IKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH 224
K+HTGDK Y C EC AF S HL H K HT KPYKC C + SSSS H ++H
Sbjct: 212 KKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVISSSSSFAKHKRIH 271
Query: 225 ERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
K KC +C + F+ L KH H P C
Sbjct: 272 TGEKPF----------------KCLECGKAFNISTTLTKH-RRIHTGEKP------YTCE 308
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN 342
C + F + +L H ++H+GEK +C C ++F LY H H ++P C
Sbjct: 309 VCGKAFRQSANLYVH-RRIHTGEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYKCEDCG 367
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
K+ GR A Q + +
Sbjct: 368 ------------------------------------KAFGRYTALNQHKKI-----HTGE 386
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K F+S L H + +KP + C+ NLNE+ K++H
Sbjct: 387 KPYKCEECGKA-FNSSTNLTAHKRIHTREKP---YTCEDRGRAFGLSTNLNEY-KKIHTG 441
Query: 463 QDPGLIVSAMPAIV-----------------YQCNFCSEVVNDLNTLQEHIRCSHGFANP 505
P A + Y+C C +V+ ++ +H R G
Sbjct: 442 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTG---- 497
Query: 506 AAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYC 565
F C C F + ++L +H R++H T ++P Y+C C
Sbjct: 498 ----EKPFECLECGKAFTSSTTLTKH-RRIH--------------TGEKP----YTCEVC 534
Query: 566 TNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGG 625
+ +++L +++ I H G+K + +L + + +
Sbjct: 535 GKAFRQSAILYVHRRI--------------HTGEKPYTCEECGKTFRQSANLYVHRRIH- 579
Query: 626 APARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHV 683
TGE Y C +CG + H K H L K C +C K+F L +
Sbjct: 580 -----TGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYK--CEECGKDFVWYTDLNQQK 632
Query: 684 TIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAV 743
I+ Y CE C K F DL +H + ++C C + F +++ H +
Sbjct: 633 KIY--TGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKKI 690
Query: 744 KHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH-- 801
H+ EK Y+C C F +L H + + K +KC G SFG L +
Sbjct: 691 -HTGEKP-YKCEECGKAFSRSRNL---TTHRRVHTREKPYKCEDRGRSFGWSTNLNEYKK 745
Query: 802 ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG---TNGAS----EQVQKE 854
I T K Y CK C K F L +H + K CG T+ +S +++
Sbjct: 746 IHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSSSSFAKHKRIHTG 805
Query: 855 EVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHN---- 910
E + L + ++ + T E Y C+ CG A+ +L H+ R H
Sbjct: 806 EKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAILYVHR-RIHTGEKP 864
Query: 911 ---------IRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLG 954
R + KK + Y C C +TF L H + H G
Sbjct: 865 YTCGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKIHTG 917
Score = 156 bits (394), Expect = 1e-37
Identities = 197/834 (23%), Positives = 288/834 (34%), Gaps = 147/834 (17%)
Query: 513 FFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFG-------SPVLGTPKEPVVE 558
F C C F S L +H + +H C+ G FG + T ++P
Sbjct: 109 FKCNECGKSFQKFSDLTQH-KGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHTGEKP--- 164
Query: 559 VYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLK 618
Y C C + FN L H + IHN +K+ T+L
Sbjct: 165 -YKCEECGKA--FNRSTNLTAHKR------------IHNREKAYTGEDRDRAFGWSTNLN 209
Query: 619 MMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQ 676
+ + TG+ Y C +CG + H K H T C +C K +
Sbjct: 210 EYKKIH------TGDKPYKCKECGKAFMHSSHLNKHEKIH--TGEKPYKCKECGKVISSS 261
Query: 677 ESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVS 736
S KH IH + C C K F L KH + C +C + F +
Sbjct: 262 SSFAKHKRIH--TGEKPFKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFRQSAN 319
Query: 737 IQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEV 796
+ +H + H+ EK Y C C FR +L +H + K +KC CG++FG
Sbjct: 320 LYVHRRI-HTGEKP-YTCGECGKTFRQSANLYVH---RRIHTGEKPYKCEDCGKAFGRYT 374
Query: 797 ELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKE 854
L H I T K Y C+ C KAF++ L H K K C G +
Sbjct: 375 ALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAH---KRIHTREKPYTCEDRGRAFG---- 427
Query: 855 EVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPG 914
L TN E H G + Y C CG A+ L H+
Sbjct: 428 ------LSTNLNEYKKIHTGDKP--------YKCKECGKAFIHSLHLNKHE--------- 464
Query: 915 ESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTL 974
K K YKC C + S + +H + H G K + C CG+ F S TL
Sbjct: 465 -------KIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGE-KPFECLECGKAFTSSTTL 516
Query: 975 TEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLE 1034
T+H+ H+ C +C + H ++H + + C C +T +
Sbjct: 517 TKHRRIHTGEKPY-TCEVCGKAFRQSAILYVHRRIHTGEKP----YTCEECGKTFRQSAN 571
Query: 1035 LKIHGTFHM-------QKTGNGSAVQTTGRGQHV-----QKLYKCASCLKEFRSKQDL-- 1080
L +H H ++ G + T QH +KLYKC C K+F DL
Sbjct: 572 LYVHRRIHTGEKPYKCEECGKAFG-RYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLNQ 630
Query: 1081 -VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKT- 1138
K+ PY C K+ +P ++ T + E E GK G
Sbjct: 631 QKKIYTGEKPYK----CEECGKAFAPSTDLNQHTK---ILTGEQSYKCEECGKAFGWSIA 683
Query: 1139 --------------RCSSCNVKFESESELQNHIQTIHREL---VPDSNSTQLKTPQVSPM 1181
+C C F L H + RE D + + ++
Sbjct: 684 LNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNEY 743
Query: 1182 PRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQ 1241
+I K Y+C +C VF + H H + ++CK C + S +
Sbjct: 744 KKIHTGD----KLYKCKECGKVFKQSSHLNRHEKIHTGKKP--YKCKECGKVITSSSSFA 797
Query: 1242 CHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKF 1295
H H+ E FKC C F + L +H G +K Y C +C + F
Sbjct: 798 KHKRIHTGE---KPFKCLECGKAFTSSTTLTKHRRIHTG--EKPYTCEECGKAF 846
Score = 137 bits (345), Expect = 7e-32
Identities = 201/905 (22%), Positives = 314/905 (34%), Gaps = 158/905 (17%)
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
+ C C K F + L H K +H E+ + C+ + +LN+H K++H +
Sbjct: 109 FKCNECGKS-FQKFSDLTQH-KGIHAG--EKPYTCEERGKDFGWYTDLNQH-KKIHTGEK 163
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLT 524
P Y+C C + N L H R + +D + F G+ T
Sbjct: 164 P-----------YKCEECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAF------GWST 206
Query: 525 DSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKEN 584
+ L E+ +++H T +P Y C C + + +S LNKH K
Sbjct: 207 N--LNEY-KKIH--------------TGDKP----YKCKECGKAFMHSS--HLNKHEK-- 241
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAK 642
IH G+K V +S + + TGE + C +CG
Sbjct: 242 ----------IHTGEKPYKCKECGKVISSSSSFAKHKRIH------TGEKPFKCLECGKA 285
Query: 643 YTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQ 702
+ + H + H T TC C K F +L H IH Y C C K
Sbjct: 286 FNISTTLTKHRRIH--TGEKPYTCEVCGKAFRQSANLYVHRRIH--TGEKPYTCGECGKT 341
Query: 703 FTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFR 762
F +L H ++C C + F ++ H + H+ EK Y+C C F
Sbjct: 342 FRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKI-HTGEKP-YKCEECGKAFN 399
Query: 763 NETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHA 820
+ T+L H + + K + C G +FG L + I T K Y CK C KAF
Sbjct: 400 SSTNL---TAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIH 456
Query: 821 IILLEKHLREKHCVFETKTPNCG---TNGAS----EQVQKEEVELQTLLTNSQESHNSHD 873
+ L KH + K CG T+ +S +++ E + L + ++
Sbjct: 457 SLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTTL 516
Query: 874 GSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHN-------------IRPGESAIVK 920
+ T E Y C++CG A+ +L H+ R H R + V
Sbjct: 517 TKHRRIHTGEKPYTCEVCGKAFRQSAILYVHR-RIHTGEKPYTCEECGKTFRQSANLYVH 575
Query: 921 KKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHK-- 978
++ + YKC C + F L +H + H G K Y C CG+ F L + K
Sbjct: 576 RRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGE-KLYKCEECGKDFVWYTDLNQQKKI 634
Query: 979 VTHSKSLDTGNCRICKMP----------LQSEEEF-LEHC----------QMHPDLRNSL 1017
T K C P L E+ + E C H +
Sbjct: 635 YTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKKIHTGE 694
Query: 1018 TGFRCVVCMQTVTSTLELKIHGTFHMQKT-----------GNGSAVQTTGRGQHVQKLYK 1066
++C C + + + L H H ++ G + + + KLYK
Sbjct: 695 KPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYK 754
Query: 1067 CASCLKEFRSKQDL---VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNEN 1123
C C K F+ L K+ PY C C + S+S
Sbjct: 755 CKECGKVFKQSSHLNRHEKIHTGKKPY-KCKECGKVITSSSS------------------ 795
Query: 1124 LSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPR 1183
A + G +C C F S + L H + IH P + K + S +
Sbjct: 796 -FAKHKRIHTGEKPFKCLECGKAFTSSTTLTKH-RRIHTGEKPYTCEECGKAFRQSAILY 853
Query: 1184 ISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCH 1243
+ +K Y C +C F ++ H H ++ + C C +TF A L H
Sbjct: 854 VHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEK--PYTCGDCGKTFRQSANLYAH 911
Query: 1244 LIEHS 1248
H+
Sbjct: 912 KKIHT 916
Score = 126 bits (316), Expect = 2e-28
Identities = 162/675 (24%), Positives = 230/675 (34%), Gaps = 103/675 (15%)
Query: 638 QCGAKYTSLDSFQTHLKTHLDTVLPK-LTCPQCNKEFPNQESLLKHVTIHFMITSTYYIC 696
QC A+ F K K C +C K F L +H IH Y C
Sbjct: 82 QCNARVKVFSKFANSNKDKTRHTGEKHFKCNECGKSFQKFSDLTQHKGIH--AGEKPYTC 139
Query: 697 ESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCT 755
E K F DL +H +HT ++C C + F+ ++ H + N +K Y
Sbjct: 140 EERGKDFGWYTDLNQHK-KIHTGEKPYKCEECGKAFNRSTNLTAHKRIH--NREKAYTGE 196
Query: 756 SCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKF 813
+ F T+L + K + K +KC CG++F L H I T K Y CK
Sbjct: 197 DRDRAFGWSTNLNEYKK---IHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKE 253
Query: 814 CSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHD 873
C K + KH R K CG + + T LT + H
Sbjct: 254 CGKVISSSSSFAKHKRIHTGEKPFKCLECG----------KAFNISTTLTKHRRIH---- 299
Query: 874 GSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCN 933
T E Y C++CG A+ L H+ I GE Y C
Sbjct: 300 -------TGEKPYTCEVCGKAFRQSANLYVHR----RIHTGEKP------------YTCG 336
Query: 934 VCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRIC 993
C +TF L H + H G K Y C CG+ F L +HK H+ C C
Sbjct: 337 ECGKTFRQSANLYVHRRIHTGE-KPYKCEDCGKAFGRYTALNQHKKIHTGEKPY-KCEEC 394
Query: 994 KMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQ 1053
S H ++H + + C + + L + H TG+
Sbjct: 395 GKAFNSSTNLTAHKRIHTREKP----YTCEDRGRAFGLSTNLNEYKKIH---TGD----- 442
Query: 1054 TTGRGQHVQKLYKCASCLKEFRSKQDL---VKLDINGLPYGLCAGCVNLSKSASPGINVP 1110
K YKC C K F L K+ PY C C + S+S
Sbjct: 443 ---------KPYKCKECGKAFIHSLHLNKHEKIHTGKKPYK-CKQCGKVITSSSS----- 487
Query: 1111 PGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNS 1170
A + G C C F S + L H + IH P +
Sbjct: 488 --------------FAKHKRIHTGEKPFECLECGKAFTSSTTLTKH-RRIHTGEKPYTCE 532
Query: 1171 TQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLC 1230
K + S + + +K Y C +C F ++ VH H ++ ++C+ C
Sbjct: 533 VCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKP--YKCEEC 590
Query: 1231 SQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQ 1290
+ F L H H+ E + +KC C FV L Q G+ K Y C +
Sbjct: 591 GKAFGRYTDLNQHKKIHTGEKL---YKCEECGKDFVWYTDLNQQKKIYTGE--KPYKCEE 645
Query: 1291 CPQKFFFQTELQNHT 1305
C + F T+L HT
Sbjct: 646 CGKAFAPSTDLNQHT 660
Score = 96.7 bits (239), Expect = 1e-19
Identities = 53/185 (28%), Positives = 87/185 (47%), Gaps = 15/185 (8%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
+ ++ C C +VF+ S + H+ ++ G C +S SS + H
Sbjct: 750 DKLYKCKECGKVFKQSSHLNRHE----KIHTGKKPYKCKECGKVITSSSSFAKHKRIHT- 804
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ P+ C C K+F+ + L H + H+ + P+ C C + F+
Sbjct: 805 ----GEK------PFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAILYV 854
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H ++HTG+K Y C EC F +S +L H K HT KPY C C + F S++L+ H ++
Sbjct: 855 HRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKI 914
Query: 224 HERNK 228
H +K
Sbjct: 915 HTGDK 919
>gi|157167158 zinc finger protein 808 [Homo sapiens]
Length = 903
Score = 226 bits (577), Expect = 8e-59
Identities = 213/870 (24%), Positives = 319/870 (36%), Gaps = 209/870 (24%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+PC K+F+ S L+ H+ H +KC C +LF HK+ H + HTG+K Y C
Sbjct: 231 FPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCK 290
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
EC +FS L H + HT KPYKC C + F +S+L H +H K
Sbjct: 291 ECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAIHTGEK--------- 341
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
KC++C + F+ L +H H P +C C + F + L
Sbjct: 342 -------PYKCNECGKAFNQQSHLSRH-QRLHTGVKP------YKCKICEKAFACHSYLA 387
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
NH ++HSGEK C+ C ++F+ L H H ++P C +
Sbjct: 388 NH-TRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKCEECD------------- 433
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLF 415
+ ST+ KR TG + KV + CN QL
Sbjct: 434 ------KVFSQKSTL----------ERHKRI------HTGEKPYKCKVCDTAFTCNSQL- 470
Query: 416 SSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAI 475
+ + E+ + C C + +L H +++H + P
Sbjct: 471 ---------ARHRRIHTGEKTYKCNECRKTFSRRSSLLCH-RRLHSGEKP---------- 510
Query: 476 VYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQV 535
Y+CN C +L H R H ++ C C F+ +S L H R
Sbjct: 511 -YKCNQCGNTFRHRASLVYHRRL-HTL-------EKSYKCTVCNKVFMRNSVLAVHTR-- 559
Query: 536 HCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYI 595
+ T K+P Y C+ C + FN L++H + +
Sbjct: 560 -------------IHTAKKP----YKCNECGKA--FNQQSHLSRHRR------------L 588
Query: 596 HNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHL 653
H G+K V ++++L+ + + TGE Y C C +T H
Sbjct: 589 HTGEKPYKCEACDKVFGQKSALESHKRI------HTGEKPYRCQVCDTAFTWNSQLARHT 642
Query: 654 KTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHL 713
+ H K C +C K F + SL+ H +H S Y C+ CDK F + KH
Sbjct: 643 RIHTGEKTYK--CNECGKTFSYKSSLVWHRRLHGGEKS--YKCKVCDKAFVCRSYVAKHT 698
Query: 714 LDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKH 773
++C C + F ++ S+ H + HS EK Y+C+ C+ F + L + H
Sbjct: 699 RIHSGMKPYKCNECSKTFSNRSSLVCHRRI-HSGEKP-YKCSECSKTFSQKATL---LCH 753
Query: 774 NHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREK 831
L + K +KC CG +F L H H+ K Y C C KAF L +H+R
Sbjct: 754 RRLHSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIR-- 811
Query: 832 HCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDIC 891
+ T+E Y C+ C
Sbjct: 812 -----------------------------------------------IHTAEKPYKCNEC 824
Query: 892 GAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQT 951
G A+ Q+H R H I GE YKC C + F ++ L+ H
Sbjct: 825 GKAFNE----QSHLSRHHRIHTGEKP------------YKCEACDKVFSRKSHLKRHRII 868
Query: 952 HLGPVKHYMCPICGERFPSLLTLTEHKVTH 981
H G K Y C CG+ F TL H+ H
Sbjct: 869 HTGE-KPYKCNECGKAFSDRSTLIHHQAIH 897
Score = 213 bits (541), Expect = 1e-54
Identities = 180/724 (24%), Positives = 290/724 (40%), Gaps = 129/724 (17%)
Query: 105 CDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRH 164
C GE+ PY C+ C KSFS S L H + H+ P+KC C ++F+ + H
Sbjct: 280 CHTGEK------PYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIH 333
Query: 165 IKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH 224
+HTG+K Y C+EC AF++ HL H + HT KPYKC IC + F S L H ++H
Sbjct: 334 KAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIH 393
Query: 225 ERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
K T KC++C + F+ L +H H P +C
Sbjct: 394 SGEK----------------TYKCNECGKAFNHQSSLARHHI-LHTGEKP------YKCE 430
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNH-- 340
C ++F ++++L H +++H+GEK C +C +F +L H H ++ CN
Sbjct: 431 ECDKVFSQKSTLERH-KRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECR 489
Query: 341 ---SNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPS 397
S SL+ + + S + +T A + R
Sbjct: 490 KTFSRRSSLLC--HRRLHSGEKPYKCNQCGNTFRHRASLVYHRR---------------- 531
Query: 398 SKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLK 457
+ +Y C CNK +F +VL +H + KP + C C + +L+ H +
Sbjct: 532 LHTLEKSYKCTVCNK-VFMRNSVLAVHTRIHTAKKP---YKCNECGKAFNQQSHLSRH-R 586
Query: 458 QVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPH 517
++H + P Y+C C +V + L+ H R G + C
Sbjct: 587 RLHTGEKP-----------YKCEACDKVFGQKSALESHKRIHTG--------EKPYRCQV 627
Query: 518 CYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKL 577
C F +S L H R +H +G + Y C+ C + + S L
Sbjct: 628 CDTAFTWNSQLARHTR-IH---TGEK---------------TYKCNECGKTFSYKSSLVW 668
Query: 578 NKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICN 637
++ +H G+KS + ++ + + +P Y CN
Sbjct: 669 HRR--------------LHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSG-MKP---YKCN 710
Query: 638 QCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICE 697
+C +++ S H + H K C +C+K F + +LL H +H Y C
Sbjct: 711 ECSKTFSNRSSLVCHRRIHSGEKPYK--CSECSKTFSQKATLLCHRRLH--SGEKPYKCN 766
Query: 698 SCDKQFTSVDDLQKHLLDMHT-FVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTS 756
C F L H +HT ++CT+C + F + H+ + H+ EK Y+C
Sbjct: 767 DCGNTFRHWSSLVYH-RRLHTGEKSYKCTVCDKAFVRNSYLARHIRI-HTAEKP-YKCNE 823
Query: 757 CNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFC 814
C F ++ L +H+ + K +KC C + F + L+ H I T K Y C C
Sbjct: 824 CGKAFNEQSHLS---RHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNEC 880
Query: 815 SKAF 818
KAF
Sbjct: 881 GKAF 884
Score = 191 bits (484), Expect = 5e-48
Identities = 165/667 (24%), Positives = 261/667 (39%), Gaps = 137/667 (20%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C+ C+K+F+ SYL +H + HS + +KC C + F H+ S RH LHTG+K Y C
Sbjct: 370 PYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKC 429
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
ECD FS+ L+ H + HT KPYKC +C F +S L H ++H K
Sbjct: 430 EECDKVFSQKSTLERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEK-------- 481
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
T KC++C + F L CH E +C C F SL
Sbjct: 482 --------TYKCNECRKTFSRRSSLL-----CHRRLHSGE--KPYKCNQCGNTFRHRASL 526
Query: 297 MNHMEQVHSGEKKNSCSICSESF--HTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSV 354
+ H ++H+ EK C++C++ F ++V +++ + + ++P CN
Sbjct: 527 VYH-RRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECG------------ 573
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
+ S+L SR R+ + P Y C C+K +
Sbjct: 574 KAFNQQSHL----------------SRHRRLHTGEKP-------------YKCEACDK-V 603
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
F + L+ H K +H E+ + CQ C L H + +H +
Sbjct: 604 FGQKSALESH-KRIHTG--EKPYRCQVCDTAFTWNSQLARHTR-IHTGEK---------- 649
Query: 475 IVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQ 534
Y+CN C + + ++L H R G ++ C C F+ S + +H R
Sbjct: 650 -TYKCNECGKTFSYKSSLVWHRRLHGG--------EKSYKCKVCDKAFVCRSYVAKHTR- 699
Query: 535 VHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNY 594
+H SG ++ Y C+ C+ + S L ++
Sbjct: 700 IH---SG---------------MKPYKCNECSKTFSNRSSLVCHRR-------------- 727
Query: 595 IHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLK 654
IH+G+K S S ++ +L + + Y CN CG + S H +
Sbjct: 728 IHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEK----PYKCNDCGNTFRHWSSLVYHRR 783
Query: 655 THLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLL 714
H T C C+K F L +H+ IH Y C C K F L +H
Sbjct: 784 LH--TGEKSYKCTVCDKAFVRNSYLARHIRIH--TAEKPYKCNECGKAFNEQSHLSRHHR 839
Query: 715 DMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHN 774
++C C +VF K ++ H + H+ EK Y+C C F + + L + H
Sbjct: 840 IHTGEKPYKCEACDKVFSRKSHLKRHRII-HTGEKP-YKCNECGKAFSDRSTL---IHHQ 894
Query: 775 HLENQGK 781
+ GK
Sbjct: 895 AIHGIGK 901
Score = 165 bits (418), Expect = 2e-40
Identities = 187/804 (23%), Positives = 279/804 (34%), Gaps = 175/804 (21%)
Query: 477 YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH 536
Y+C+ C ++ N L H RC G + C C F SSL H R
Sbjct: 259 YKCDVCGKLFNHKQYLACHRRCHTG--------EKPYKCKECGKSFSYKSSLTCHHR--- 307
Query: 537 CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIH 596
L T +P Y C+ C NS L ++K I H
Sbjct: 308 ------------LHTGVKP----YKCNECGKVFRQNSALVIHKAI--------------H 337
Query: 597 NGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTH 656
G+K + +Q+ L Q + +P Y C C + H + H
Sbjct: 338 TGEKPYKCNECGKAFNQQSHLSRHQRLHTG-VKP---YKCKICEKAFACHSYLANHTRIH 393
Query: 657 LDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDM 716
K C +C K F +Q SL +H +H Y CE CDK F+ L++H
Sbjct: 394 SGEKTYK--CNECGKAFNHQSSLARHHILH--TGEKPYKCEECDKVFSQKSTLERHKRIH 449
Query: 717 HTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHL 776
++C +C F + H + H+ EK Y+C C F + L + H L
Sbjct: 450 TGEKPYKCKVCDTAFTCNSQLARHRRI-HTGEK-TYKCNECRKTFSRRSSL---LCHRRL 504
Query: 777 ENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCV 834
+ K +KC CG +F L H H+ K Y C C+K F +L H R
Sbjct: 505 HSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAK 564
Query: 835 FETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAA 894
K CG +Q+SH S + T E Y C+ C
Sbjct: 565 KPYKCNECGK------------------AFNQQSHLSR---HRRLHTGEKPYKCEACDKV 603
Query: 895 YTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLG 954
+ ++ L++H+ I GE Y+C VC F + L H + H G
Sbjct: 604 FGQKSALESHK----RIHTGEKP------------YRCQVCDTAFTWNSQLARHTRIHTG 647
Query: 955 PVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLR 1014
K Y C CG+ F +L H+ H + C++C +H ++H ++
Sbjct: 648 E-KTYKCNECGKTFSYKSSLVWHRRLHGGE-KSYKCKVCDKAFVCRSYVAKHTRIHSGMK 705
Query: 1015 NSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEF 1074
++C C +T ++ L H H +K YKC+ C K F
Sbjct: 706 P----YKCNECSKTFSNRSSLVCHRRIHSG-----------------EKPYKCSECSKTF 744
Query: 1075 RSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKG 1131
K L+ +L PY C C N + S L + L
Sbjct: 745 SQKATLLCHRRLHSGEKPY-KCNDCGNTFRHWS------------SLVYHRRL------- 784
Query: 1132 KVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDE 1191
G +C+ C+ F S L HI+ IH
Sbjct: 785 HTGEKSYKCTVCDKAFVRNSYLARHIR-IH----------------------------TA 815
Query: 1192 KKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFE 1250
+K Y+C +C F + + H H I G ++C+ C + F + L+ H I H+ E
Sbjct: 816 EKPYKCNECGKAFNEQSHLSRH---HRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGE 872
Query: 1251 GMGGTFKCPVCFTVFVQANKLQQH 1274
+KC C F + L H
Sbjct: 873 ---KPYKCNECGKAFSDRSTLIHH 893
Score = 158 bits (400), Expect = 3e-38
Identities = 177/708 (25%), Positives = 257/708 (36%), Gaps = 142/708 (20%)
Query: 636 CNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYI 695
CN+ G + + H HL K C C K F +++ L H H Y
Sbjct: 233 CNESGKAFNCSSLLRKHQIPHLGDKQYK--CDVCGKLFNHKQYLACHRRCH--TGEKPYK 288
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRC 754
C+ C K F+ L H +HT V ++C C +VF ++ +H A+ H+ EK Y+C
Sbjct: 289 CKECGKSFSYKSSLTCHHR-LHTGVKPYKCNECGKVFRQNSALVIHKAI-HTGEKP-YKC 345
Query: 755 TSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCK 812
C F ++ L +H L K +KC C ++F L H HS K Y C
Sbjct: 346 NECGKAFNQQSHLS---RHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCN 402
Query: 813 FCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSH 872
C KAF+ L +H H + + P E+ K + TL E H
Sbjct: 403 ECGKAFNHQSSLARH----HILHTGEKPY-----KCEECDKVFSQKSTL-----ERHKR- 447
Query: 873 DGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKC 932
+ T E Y C +C A+T + L H+ I GE YKC
Sbjct: 448 ------IHTGEKPYKCKVCDTAFTCNSQLARHR----RIHTGEKT------------YKC 485
Query: 933 NVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRI 992
N C +TF + L H + H G K Y C CG F +L H+ H+ + C +
Sbjct: 486 NECRKTFSRRSSLLCHRRLHSGE-KPYKCNQCGNTFRHRASLVYHRRLHTLE-KSYKCTV 543
Query: 993 CKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAV 1052
C H ++H + ++C C + L H H
Sbjct: 544 CNKVFMRNSVLAVHTRIH----TAKKPYKCNECGKAFNQQSHLSRHRRLH---------- 589
Query: 1053 QTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYG--LCAGCVNLSKSASPGI 1107
TG +K YKC +C K F K L ++ PY +C + +
Sbjct: 590 --TG-----EKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHT 642
Query: 1108 NVPPGT-----NRPGLGQNENLSAIEGKGKVGGLKT-RCSSCNVKFESESELQNHIQTIH 1161
+ G N G + S + + GG K+ +C C+ F S + H + IH
Sbjct: 643 RIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTR-IH 701
Query: 1162 RELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDE 1221
+ P Y+C +C F N + H H ++
Sbjct: 702 SGMKP----------------------------YKCNECSKTFSNRSSLVCHRRIHSGEK 733
Query: 1222 GLNHECKLCSQTFDSPAKLQCHLIEHSFE------GMGGTF------------------- 1256
++C CS+TF A L CH HS E G TF
Sbjct: 734 P--YKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSY 791
Query: 1257 KCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
KC VC FV+ + L +HI H E K Y C +C + F Q+ L H
Sbjct: 792 KCTVCDKAFVRNSYLARHI-RIHTAE-KPYKCNECGKAFNEQSHLSRH 837
Score = 152 bits (384), Expect = 2e-36
Identities = 168/701 (23%), Positives = 243/701 (34%), Gaps = 120/701 (17%)
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C C K FS + L H + KP + C C +V L H K +H +
Sbjct: 287 YKCKECGKS-FSYKSSLTCHHRLHTGVKPYK---CNECGKVFRQNSALVIH-KAIHTGEK 341
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLT 524
P Y+CN C + N + L H R G K F H Y+
Sbjct: 342 P-----------YKCNECGKAFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLA--N 388
Query: 525 DSSLEEHIRQVHCDLSGSRFGSP-------VLGTPKEPVVEVYSCSYCTNSPIFNSVLKL 577
+ + + C+ G F +L T ++P Y C C S L+
Sbjct: 389 HTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKP----YKCEECDKVFSQKSTLER 444
Query: 578 NKHIKENHK-------------NIPLALN-YIHNGKKSRALSPLSPVAIEQTSLKMMQAV 623
+K I K N LA + IH G+K+ + ++SL + +
Sbjct: 445 HKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRL 504
Query: 624 GGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHV 683
Y CNQCG + S H + H T+ C CNK F L H
Sbjct: 505 HSGEK----PYKCNQCGNTFRHRASLVYHRRLH--TLEKSYKCTVCNKVFMRNSVLAVHT 558
Query: 684 TIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLA 742
IH Y C C K F L +H +HT ++C C +VF K +++ H
Sbjct: 559 RIH--TAKKPYKCNECGKAFNQQSHLSRH-RRLHTGEKPYKCEACDKVFGQKSALESHKR 615
Query: 743 VKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHI 802
+ H+ EK YRC C+ F + L +H + K +KC CG++F + L H
Sbjct: 616 I-HTGEKP-YRCQVCDTAFTWNSQL---ARHTRIHTGEKTYKCNECGKTFSYKSSLVWHR 670
Query: 803 TTH--SKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQT 860
H K Y CK C KAF + KH R + K C
Sbjct: 671 RLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNEC------------------ 712
Query: 861 LLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVK 920
+ S+ S + + E Y C C ++ + L H+ +P
Sbjct: 713 ---SKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKP------- 762
Query: 921 KKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVT 980
YKCN C TF + L H + H G K Y C +C + F L H
Sbjct: 763 ---------YKCNDCGNTFRHWSSLVYHRRLHTGE-KSYKCTVCDKAFVRNSYLARHIRI 812
Query: 981 HSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGT 1040
H+ C C + H ++H + ++C C + + LK H
Sbjct: 813 HTAE-KPYKCNECGKAFNEQSHLSRHHRIHTGEK----PYKCEACDKVFSRKSHLKRHRI 867
Query: 1041 FHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV 1081
H TG +K YKC C K F + L+
Sbjct: 868 IH---TG--------------EKPYKCNECGKAFSDRSTLI 891
Score = 150 bits (378), Expect = 1e-35
Identities = 144/620 (23%), Positives = 235/620 (37%), Gaps = 125/620 (20%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F S + H I L G C S S+ ++ H
Sbjct: 396 EKTYKCNECGKAFNHQSSLARHHI----LHTGEKPYKCEECDKVFSQKSTLERHKRIH-- 449
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C+ CD +F+ S L H + H+ + +KC C + F + S
Sbjct: 450 ---TGEK------PYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLC 500
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H +LH+G+K Y C++C F L H + HT K YKC +C + F+ +S L H ++
Sbjct: 501 HRRLHSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRI 560
Query: 224 HERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQC 283
H K KC++C + F+ L +H H P +C
Sbjct: 561 HTAKK----------------PYKCNECGKAFNQQSHLSRH-RRLHTGEKP------YKC 597
Query: 284 VYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPES-----C 338
C ++F ++++L +H +++H+GEK C +C +F +L H H ++ C
Sbjct: 598 EACDKVFGQKSALESH-KRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNEC 656
Query: 339 NHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSS 398
+ S V + + V V R A+ T +G
Sbjct: 657 GKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFV----------CRSYVAKHTRIHSGMK- 705
Query: 399 KQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQ 458
Y C C+K FS+ + L H + +KP + C C + L H ++
Sbjct: 706 -----PYKCNECSK-TFSNRSSLVCHRRIHSGEKP---YKCSECSKTFSQKATLLCH-RR 755
Query: 459 VHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHC 518
+H + P Y+CN C ++L H R G ++ C C
Sbjct: 756 LHSGEKP-----------YKCNDCGNTFRHWSSLVYHRRLHTG--------EKSYKCTVC 796
Query: 519 YMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLN 578
F+ +S L HIR + T ++P Y C+ C + FN
Sbjct: 797 DKAFVRNSYLARHIR---------------IHTAEKP----YKCNECGKA--FNE----Q 831
Query: 579 KHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YIC 636
H+ +H+ IH G+K V ++ LK + + TGE Y C
Sbjct: 832 SHLSRHHR--------IHTGEKPYKCEACDKVFSRKSHLKRHRII------HTGEKPYKC 877
Query: 637 NQCGAKYTSLDSFQTHLKTH 656
N+CG ++ + H H
Sbjct: 878 NECGKAFSDRSTLIHHQAIH 897
Score = 125 bits (315), Expect = 2e-28
Identities = 135/565 (23%), Positives = 210/565 (37%), Gaps = 125/565 (22%)
Query: 745 HSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITT 804
H EK + C F + L+ H + HL + K +KC CG+ F + L CH
Sbjct: 225 HMREKS-FPCNESGKAFNCSSLLRKH-QIPHLGD--KQYKCDVCGKLFNHKQYLACHRRC 280
Query: 805 HS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLL 862
H+ K Y CK C K+F L H R V K CG +V ++
Sbjct: 281 HTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECG------KVFRQ-------- 326
Query: 863 TNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKK 922
NS + + T E Y C+ CG A+ ++ L HQ ++P
Sbjct: 327 -------NSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKP--------- 370
Query: 923 AELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHS 982
YKC +C + F + L H + H G K Y C CG+ F +L H + H+
Sbjct: 371 -------YKCKICEKAFACHSYLANHTRIHSGE-KTYKCNECGKAFNHQSSLARHHILHT 422
Query: 983 KSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFH 1042
C C + H ++H + ++C VC T +L H H
Sbjct: 423 GE-KPYKCEECDKVFSQKSTLERHKRIHTGEK----PYKCKVCDTAFTCNSQLARHRRIH 477
Query: 1043 MQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNL 1099
TG +K YKC C K F + L+ +L PY C C N
Sbjct: 478 ---TG--------------EKTYKCNECRKTFSRRSSLLCHRRLHSGEKPY-KCNQCGNT 519
Query: 1100 SKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQT 1159
+ +R L + L +E K C+ CN F ++N +
Sbjct: 520 FR------------HRASLVYHRRLHTLEKSYK-------CTVCNKVF-----MRNSVLA 555
Query: 1160 IHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMI 1219
+H T++ T KK Y+C +C F + + H H
Sbjct: 556 VH---------TRIHT---------------AKKPYKCNECGKAFNQQSHLSRHRRLHTG 591
Query: 1220 DEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAH 1279
++ ++C+ C + F + L+ H H+ E ++C VC T F ++L +H
Sbjct: 592 EK--PYKCEACDKVFGQKSALESHKRIHTGE---KPYRCQVCDTAFTWNSQLARHTRIHT 646
Query: 1280 GQEDKIYDCTQCPQKFFFQTELQNH 1304
G +K Y C +C + F +++ L H
Sbjct: 647 G--EKTYKCNECGKTFSYKSSLVWH 669
>gi|154800445 zinc finger protein 62 homolog [Homo sapiens]
Length = 840
Score = 226 bits (576), Expect = 1e-58
Identities = 222/878 (25%), Positives = 333/878 (37%), Gaps = 166/878 (18%)
Query: 131 SYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLK 190
SY +++++ K KC C + FK+ +H +HTG+K+Y C +C F S L+
Sbjct: 66 SYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLR 125
Query: 191 IHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH--ERNKDGSQSGSRMEDWKMKDTQK- 247
+H + HT KPYKC C + ++S SSL H H E+N + G + D K
Sbjct: 126 VHKRIHTGEKPYKCEECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKR 185
Query: 248 ---------CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMN 298
C +C + F L+ H H P E C C + F + L
Sbjct: 186 IHTGEKPYECGECGKAFRNSSGLRVH-KRIHTGEKPYE------CDICGKTFSNSSGLRV 238
Query: 299 HMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSS 356
H +++H+GEK C C ++F T L +H H +P C+ + Y+S
Sbjct: 239 H-KRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEK----SFNYSS--- 290
Query: 357 TTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFS 416
L + + P K + + + Y C C K FS
Sbjct: 291 ------LLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKA-FS 343
Query: 417 SLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIV 476
+ L +H K++H K +AH C+ C + L +H + +H + P
Sbjct: 344 YSSGLAVH-KSIHPGK--KAHECKECGKSFSYNSLLLQH-RTIHTGERP----------- 388
Query: 477 YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH 536
Y C+ C + + L+ H R G + C C +++ SSL+ H
Sbjct: 389 YVCDVCGKTFRNNAGLKVHRRLHTG--------EKPYKCDVCGKAYISRSSLKNH----- 435
Query: 537 CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIH 596
G G + Y CSYC S ++S L E HK I H
Sbjct: 436 ---KGIHLGE-----------KPYKCSYCEKSFNYSSAL-------EQHKRI-------H 467
Query: 597 NGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLK 654
+K + LK+ + + TGE Y C +CG Y SL S H
Sbjct: 468 TREKPFGCDECGKAFRNNSGLKVHKRIH------TGERPYKCEECGKAYISLSSLINHKS 521
Query: 655 THLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLL 714
H C +C K F +L H +H + Y C+ C+K F L +H
Sbjct: 522 VHPGE--KPFKCDECEKAFITYRTLTNHKKVH--LGEKPYKCDVCEKSFNYTSLLSQHRR 577
Query: 715 DMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHN 774
+ C C++VF + S+++H + H+ E+ Y C C + + + L H K
Sbjct: 578 VHTREKPYECDRCEKVFRNNSSLKVHKRI-HTGERP-YECDVCGKAYISHSSLINH-KST 634
Query: 775 HLENQGKV-HKCIFCGESFGTEVELQCHITTH--SKKYNCKFCSKAFHAIILLEKHLR-- 829
H GK H C CG++F + L H H K + C C K+F LL +H R
Sbjct: 635 H---PGKTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIH 691
Query: 830 --EKHCVFETKTPNCGT---NGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEP 884
EK V + CG N + V K + T E
Sbjct: 692 TGEKPYVCD----RCGKAFRNSSGLTVHKR------------------------IHTGEK 723
Query: 885 MYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENG 944
Y CD CG AY + L NH+ +P Y C C ++F +
Sbjct: 724 PYECDECGKAYISHSSLINHKSVHQGKQP----------------YNCE-CGKSFNYRSV 766
Query: 945 LREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHS 982
L +H + H G K Y C CG+ F LT+HK TH+
Sbjct: 767 LDQHKRIHTGK-KPYRCNECGKAFNIRSNLTKHKRTHT 803
Score = 216 bits (549), Expect = 1e-55
Identities = 210/817 (25%), Positives = 323/817 (39%), Gaps = 129/817 (15%)
Query: 46 VHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGC 105
+H CD C + F+ S + +HKI + G + C S SS H
Sbjct: 80 LHKCDECGKSFKYNSRLVQHKI----MHTGEKRYECDDCGGTFRSSSSLRVHKRIHT--- 132
Query: 106 DFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHI 165
GE+ PY C+ C K++ S L +H+ +HS + KC C + F + D+H
Sbjct: 133 --GEK------PYKCEECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHK 184
Query: 166 KLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH- 224
++HTG+K Y C EC AF S L++H + HT KPY+C IC + F +SS L H ++H
Sbjct: 185 RIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHT 244
Query: 225 -ERNKDGSQSGSRMEDWKM----------KDTQKCSQCEEGFDFPEDLQKHIAECHPECS 273
E+ + + G + KC +CE+ F++ L +H H
Sbjct: 245 GEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQH-KVIHTGEK 303
Query: 274 PNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH- 332
P E C C + F + L+ H +++H+GEK C +C ++F L H H
Sbjct: 304 PYE------CDECGKAFRNSSGLIVH-KRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHP 356
Query: 333 ----QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQ 388
+ + C S S + + + + ++ + V T A R
Sbjct: 357 GKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKP 416
Query: 389 QTPDMTG------PSSKQAK------VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQA 436
D+ G S K K Y C YC K F+ + L+ H + +KP
Sbjct: 417 YKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKS-FNYSSALEQHKRIHTREKP--- 472
Query: 437 HICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHI 496
C C + + L H K++H + P Y+C C + L++L
Sbjct: 473 FGCDECGKAFRNNSGLKVH-KRIHTGERP-----------YKCEECGKAYISLSSL---- 516
Query: 497 RCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPV 556
+H +P K F C C F+T +L H ++VH LG
Sbjct: 517 -INHKSVHPGEK---PFKCDECEKAFITYRTLTNH-KKVH------------LGE----- 554
Query: 557 VEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTS 616
+ Y C C S FN L++H + +H +K V +S
Sbjct: 555 -KPYKCDVCEKS--FNYTSLLSQHRR------------VHTREKPYECDRCEKVFRNNSS 599
Query: 617 LKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFP 674
LK+ + + TGE Y C+ CG Y S S H TH TC +C K F
Sbjct: 600 LKVHKRI------HTGERPYECDVCGKAYISHSSLINHKSTHPGKT--PHTCDECGKAFF 651
Query: 675 NQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSK 734
+ +L+ H +H + + C C K F+ L +H + C C + F +
Sbjct: 652 SSRTLISHKRVH--LGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDRCGKAFRNS 709
Query: 735 VSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGT 794
+ +H + H+ EK Y C C + + + L + H + +QGK CG+SF
Sbjct: 710 SGLTVHKRI-HTGEKP-YECDECGKAYISHSSL---INHKSV-HQGKQPYNCECGKSFNY 763
Query: 795 EVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLR 829
L H I T K Y C C KAF+ L KH R
Sbjct: 764 RSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKR 800
Score = 181 bits (459), Expect = 4e-45
Identities = 188/800 (23%), Positives = 298/800 (37%), Gaps = 165/800 (20%)
Query: 14 DPNCKLEDKTED---GEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQC 70
+ NCK ++ + LD KR GE+ + C C + F + S + HK
Sbjct: 162 EKNCKCDECGKSFNYSSVLDQHKRIHTGEK-----PYECGECGKAFRNSSGLRVHK---- 212
Query: 71 QLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRL 130
++ G + C S+ S H GE+ PY C C K+F
Sbjct: 213 RIHTGEKPYECDICGKTFSNSSGLRVHKRIHT-----GEK------PYECDECGKAFITC 261
Query: 131 SYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLK 190
L +H+ H P+KC C + F + +H +HTG+K Y C EC AF S L
Sbjct: 262 RTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLI 321
Query: 191 IHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQ 250
+H + HT KPYKC +C + F SS L H +H K +C +
Sbjct: 322 VHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKK----------------AHECKE 365
Query: 251 CEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKN 310
C + F + L +H H P C C + F L H ++H+GEK
Sbjct: 366 CGKSFSYNSLLLQH-RTIHTGERP------YVCDVCGKTFRNNAGLKVH-RRLHTGEKPY 417
Query: 311 SCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSS 368
C +C +++ + L +H H ++P C++ S + S
Sbjct: 418 KCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEK--------------------SFNYS 457
Query: 369 TMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTM 428
+ +E + ++ ++ P + C C K F + + L++H K +
Sbjct: 458 SALE--------QHKRIHTREKP-------------FGCDECGK-AFRNNSGLKVH-KRI 494
Query: 429 HLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVND 488
H E+ + C+ C + SL +L H K VH + P ++C+ C +
Sbjct: 495 HTG--ERPYKCEECGKAYISLSSLINH-KSVHPGEKP-----------FKCDECEKAFIT 540
Query: 489 LNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPV 548
TL H + G + C C F S L +H R+VH
Sbjct: 541 YRTLTNHKKVHLG--------EKPYKCDVCEKSFNYTSLLSQH-RRVH------------ 579
Query: 549 LGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLS 608
T ++P Y C C NS LK++K IH G++
Sbjct: 580 --TREKP----YECDRCEKVFRNNSSLKVHKR--------------IHTGERPYECDVCG 619
Query: 609 PVAIEQTSLKMMQAV--GGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTC 666
I +SL ++ G P + C++CG + S + +H + HL C
Sbjct: 620 KAYISHSSLINHKSTHPGKTP------HTCDECGKAFFSSRTLISHKRVHLGE--KPFKC 671
Query: 667 PQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTL 726
+C K F L +H IH Y+C+ C K F + L H + C
Sbjct: 672 VECGKSFSYSSLLSQHKRIH--TGEKPYVCDRCGKAFRNSSGLTVHKRIHTGEKPYECDE 729
Query: 727 CQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCI 786
C + + S S+ H +V K+ Y C C F + L +H + K ++C
Sbjct: 730 CGKAYISHSSLINHKSVHQG--KQPYNC-ECGKSFNYRSVLD---QHKRIHTGKKPYRCN 783
Query: 787 FCGESFGTEVELQCHITTHS 806
CG++F L H TH+
Sbjct: 784 ECGKAFNIRSNLTKHKRTHT 803
Score = 156 bits (395), Expect = 1e-37
Identities = 176/740 (23%), Positives = 270/740 (36%), Gaps = 115/740 (15%)
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYT 644
H+ +P+ GK+ ++ S +++Q + + + + C++CG +
Sbjct: 43 HQTMPIGQRGSEQGKRVENINGTSYPSLQQKTNAVKKL-----------HKCDECGKSFK 91
Query: 645 SLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFT 704
H H T + C C F + SL H IH Y CE C K +
Sbjct: 92 YNSRLVQHKIMH--TGEKRYECDDCGGTFRSSSSLRVHKRIH--TGEKPYKCEECGKAYM 147
Query: 705 SVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNE 764
S L H +C C + F+ + H + H+ EK Y C C FRN
Sbjct: 148 SYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRI-HTGEKP-YECGECGKAFRNS 205
Query: 765 TDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAII 822
+ L++H + + K ++C CG++F L+ H I T K Y C C KAF I
Sbjct: 206 SGLRVHKR---IHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAF---I 259
Query: 823 LLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTS 882
L K F K C ++ +K +LL + H T
Sbjct: 260 TCRTLLNHKSIHFGDKPYKC------DECEKS-FNYSSLLIQHKVIH-----------TG 301
Query: 883 EPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSE 942
E Y CD CG A+ R IV K+ + YKC+VC + F
Sbjct: 302 EKPYECDECGKAF----------------RNSSGLIVHKRIHTGEKPYKCDVCGKAFSYS 345
Query: 943 NGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN----CRICKMPLQ 998
+GL H H G K + C CG+ F L +H+ H TG C +C +
Sbjct: 346 SGLAVHKSIHPGK-KAHECKECGKSFSYNSLLLQHRTIH-----TGERPYVCDVCGKTFR 399
Query: 999 SEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRG 1058
+ H ++H + ++C VC + S LK H H+
Sbjct: 400 NNAGLKVHRRLHTGEK----PYKCDVCGKAYISRSSLKNHKGIHLG-------------- 441
Query: 1059 QHVQKLYKCASCLKEFRSKQDL---VKLDINGLPYGLCAGCVNLSKSASPGINV------ 1109
+K YKC+ C K F L ++ P+G C C ++ S G+ V
Sbjct: 442 ---EKPYKCSYCEKSFNYSSALEQHKRIHTREKPFG-CDECGKAFRNNS-GLKVHKRIHT 496
Query: 1110 ---PPGTNRPGLGQNENLSAIEGKGKVGGLKT-RCSSCNVKFESESELQNHIQTIHRELV 1165
P G S I K G K +C C F + L NH + +H
Sbjct: 497 GERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLTNH-KKVHLGEK 555
Query: 1166 PDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNH 1225
P K+ + + +K Y+C +C+ VF N ++VH H + +
Sbjct: 556 PYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIHTGER--PY 613
Query: 1226 ECKLCSQTFDSPAKLQCHLIEHSFEGMGGT-FKCPVCFTVFVQANKLQQHIFSAHGQEDK 1284
EC +C + + S + LI H G T C C F + L H G +K
Sbjct: 614 ECDVCGKAYISHSS----LINHKSTHPGKTPHTCDECGKAFFSSRTLISHKRVHLG--EK 667
Query: 1285 IYDCTQCPQKFFFQTELQNH 1304
+ C +C + F + + L H
Sbjct: 668 PFKCVECGKSFSYSSLLSQH 687
Score = 155 bits (392), Expect = 2e-37
Identities = 199/884 (22%), Positives = 308/884 (34%), Gaps = 173/884 (19%)
Query: 447 PSLYNLNEHLKQVHEAQDPGLIVSAMPAIV-----------YQCNFCSEVVNDLNTLQEH 495
PSL +K++H+ + G +V Y+C+ C ++L+ H
Sbjct: 68 PSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVH 127
Query: 496 IRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEP 555
R G + C C +++ SSL H + H +
Sbjct: 128 KRIHTG--------EKPYKCEECGKAYMSYSSLINH-KSTHSGEKNCK------------ 166
Query: 556 VVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQT 615
C C S ++SVL + HK I H G+K +
Sbjct: 167 ------CDECGKSFNYSSVL-------DQHKRI-------HTGEKPYECGECGKAFRNSS 206
Query: 616 SLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEF 673
L++ + + TGE Y C+ CG +++ + H + H T C +C K F
Sbjct: 207 GLRVHKRIH------TGEKPYECDICGKTFSNSSGLRVHKRIH--TGEKPYECDECGKAF 258
Query: 674 PNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDS 733
+LL H +IHF Y C+ C+K F L +H + + C C + F +
Sbjct: 259 ITCRTLLNHKSIHF--GDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRN 316
Query: 734 KVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFG 793
+ +H + H+ EK Y+C C F + L +H + K H+C CG+SF
Sbjct: 317 SSGLIVHKRI-HTGEKP-YKCDVCGKAFSYSSGLAVH---KSIHPGKKAHECKECGKSFS 371
Query: 794 TEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQV 851
L H T H+ + Y C C K F L+ H R K CG S
Sbjct: 372 YNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRSS 431
Query: 852 QKEEV-----ELQTLLTNSQESHNSHDGSEED--VDTSEPMYGCDICGAAYTMETLLQNH 904
K E + ++S N E+ + T E +GCD CG A+ + L+ H
Sbjct: 432 LKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVH 491
Query: 905 QLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPIC 964
+ RP YKC C + + S + L H H G K + C C
Sbjct: 492 KRIHTGERP----------------YKCEECGKAYISLSSLINHKSVHPGE-KPFKCDEC 534
Query: 965 GERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVV 1024
+ F + TLT HK H C +C+ +H ++H + + C
Sbjct: 535 EKAFITYRTLTNHKKVHLGEKPY-KCDVCEKSFNYTSLLSQHRRVHTREKP----YECDR 589
Query: 1025 CMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLD 1084
C + + LK+H H TG ++ Y+C C K + S L+
Sbjct: 590 CEKVFRNNSSLKVHKRIH------------TG-----ERPYECDVCGKAYISHSSLIN-- 630
Query: 1085 INGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKG-KVGGLKTRCSSC 1143
KS PG P + G + + I K +G +C C
Sbjct: 631 ---------------HKSTHPG-KTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVEC 674
Query: 1144 NVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMV 1203
F S L H + IH +K Y C +C
Sbjct: 675 GKSFSYSSLLSQH-KRIHTG----------------------------EKPYVCDRCGKA 705
Query: 1204 FYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFT 1263
F N + VH H ++ +EC C + + S + L H H + + C C
Sbjct: 706 FRNSSGLTVHKRIHTGEKP--YECDECGKAYISHSSLINHKSVHQGKQ---PYNCE-CGK 759
Query: 1264 VFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMT 1307
F + L QH G+ K Y C +C + F ++ L H T
Sbjct: 760 SFNYRSVLDQHKRIHTGK--KPYRCNECGKAFNIRSNLTKHKRT 801
Score = 71.2 bits (173), Expect = 6e-12
Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K++ S L +H+ H K P+ C C + F ++ D+H ++HTG K Y C
Sbjct: 724 PYECDECGKAYISHSSLINHKSVHQGKQPYNCE-CGKSFNYRSVLDQHKRIHTGKKPYRC 782
Query: 177 SECDAAFSRSDHLKIHLKTHTSNK 200
+EC AF+ +L H +THT +
Sbjct: 783 NECGKAFNIRSNLTKHKRTHTGEE 806
>gi|156627573 zinc finger protein 836 [Homo sapiens]
Length = 936
Score = 214 bits (545), Expect = 4e-55
Identities = 196/747 (26%), Positives = 296/747 (39%), Gaps = 120/747 (16%)
Query: 115 GLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 174
G PY C C K F + S L +H +SH+ + P+KC C + F + H ++HTG+K Y
Sbjct: 271 GKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEKPY 330
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSG 234
C+EC F + L H HT KPY+C IC + F +S+L H ++H K
Sbjct: 331 KCNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNLVNHQRIHTGEK------ 384
Query: 235 SRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEET 294
KC+ C + F +L H H P +C C + F +
Sbjct: 385 ----------PYKCNICGKSFSQSSNLATH-QTVHSGNKP------YKCDECGKTFKRSS 427
Query: 295 SLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN---SPSLVTV 349
SL H + +H+GEK +C +C + F +L H SH ++P CN S + V
Sbjct: 428 SLTTH-QIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLV 486
Query: 350 GYTSVSSTTPDSNLSVDSSTMVEAA----PPIPKSRGRKRAAQQTPDMTGPSS------- 398
G+ + + + + I +R ++ + + +S
Sbjct: 487 GHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLR 546
Query: 399 -KQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLK 457
+ Y C C K +F+ L IH + +KP Q C C V + L HL+
Sbjct: 547 IHTGEQPYKCNVCGK-VFNYSGNLSIHKRIHTGEKPFQ---CNECGTVFRNYSCLARHLR 602
Query: 458 QVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPH 517
+H Q P Y+CN C +V ND L H R G F C
Sbjct: 603 -IHTGQKP-----------YKCNVCGKVFNDSGNLSNHKRIHTG--------EKPFQCNE 642
Query: 518 CYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKL 577
C F S L H R++H T ++P Y C+ C + + L
Sbjct: 643 CGKVFSYYSCLARH-RKIH--------------TGEKP----YKCNDCGKA--YTQRSSL 681
Query: 578 NKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YI 635
KH+ IH G+K + I+ + L PTGE +
Sbjct: 682 TKHL------------IIHTGEKPYNCNEFGGAFIQSSKLARYH------RNPTGEKPHK 723
Query: 636 CNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYI 695
C+ CG ++ + H + H + K C +C + F + +L +H IH Y
Sbjct: 724 CSHCGRTFSHITGLTYHQRRHTGEMPYK--CIECGQVFNSTSNLARHRRIH--TGEKPYK 779
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRC 754
C C K F L +H +HT + C C + F + SI ++ H+ +K Y+C
Sbjct: 780 CNECGKVFRHQSTLARH-RSIHTGEKPYVCNECGKAFRVR-SILVNHQKMHTGDKP-YKC 836
Query: 755 TSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCK 812
C F + L H +++ E K +KCI CG++FG L H HS K Y C
Sbjct: 837 NECGKAFIERSKLVYHQRNHTGE---KPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCN 893
Query: 813 FCSKAFHAIILLEKHLREKHCVFETKT 839
C K+F + L KH + KH KT
Sbjct: 894 ECGKSFISRSGLTKH-QTKHTAESLKT 919
Score = 208 bits (529), Expect = 3e-53
Identities = 212/894 (23%), Positives = 325/894 (36%), Gaps = 184/894 (20%)
Query: 124 DKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAF 183
+ F +LS E++H + P+ C C + F+ S H +HT +K Y C+EC AF
Sbjct: 196 ENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAF 255
Query: 184 SRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMK 243
R L IH HT KPY+C +C + F +S L H + H K
Sbjct: 256 HRGSLLTIHQIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKP-------------- 301
Query: 244 DTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQV 303
KC++C + F +L H H P +C C + F + + L H + +
Sbjct: 302 --YKCNECGKSFSQSYNLAIH-QRIHTGEKP------YKCNECGKTFKQGSCLTTH-QII 351
Query: 304 HSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDS 361
H+GEK C IC + F L +H H ++P CN S + S
Sbjct: 352 HTGEKPYQCDICGKVFRQNSNLVNHQRIHTGEKPYKCNICGK------------SFSQSS 399
Query: 362 NLSVDSSTMVEAAPPIPKSRGR--KRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLA 419
NL+ + P G+ KR++ T T + Y+C C+K +FS +
Sbjct: 400 NLATHQTVHSGNKPYKCDECGKTFKRSSSLT---THQIIHTGEKPYTCDVCDK-VFSQRS 455
Query: 420 VLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQC 479
L H ++ +KP + C C +V +L H +++H + P Y+C
Sbjct: 456 QLARHQRSHTGEKPYK---CNECGKVFSQTSHLVGH-RRIHTGEKP-----------YKC 500
Query: 480 NFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDL 539
+ C + + L H + H + C C F +S L H+R
Sbjct: 501 DKCGKAFKQGSLLTRH-KIIH-------TREKRYQCGECGKVFSENSCLVRHLR------ 546
Query: 540 SGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGK 599
+ T ++P Y C+ C +FN L+ H + IH G+
Sbjct: 547 ---------IHTGEQP----YKCNVC--GKVFNYSGNLSIHKR------------IHTGE 579
Query: 600 KSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDT 659
K + CN+CG + + HL+ H T
Sbjct: 580 KP--------------------------------FQCNECGTVFRNYSCLARHLRIH--T 605
Query: 660 VLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTF 719
C C K F + +L H IH + C C K F+ L +H +HT
Sbjct: 606 GQKPYKCNVCGKVFNDSGNLSNHKRIH--TGEKPFQCNECGKVFSYYSCLARHR-KIHTG 662
Query: 720 VF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLEN 778
++C C + + + S+ HL + H+ EK Y C F + L +++
Sbjct: 663 EKPYKCNDCGKAYTQRSSLTKHLII-HTGEKP-YNCNEFGGAFIQSSKL---ARYHRNPT 717
Query: 779 QGKVHKCIFCGESFGTEVELQCHITTHSKK--YNCKFCSKAFHAIILLEKHLREKHCVFE 836
K HKC CG +F L H H+ + Y C C + F++ L +H R
Sbjct: 718 GEKPHKCSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKP 777
Query: 837 TKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYT 896
K CG H S + T E Y C+ CG A+
Sbjct: 778 YKCNECG---------------------KVFRHQSTLARHRSIHTGEKPYVCNECGKAFR 816
Query: 897 METLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPV 956
+ ++L NHQ +P YKCN C + F + L H + H G
Sbjct: 817 VRSILVNHQKMHTGDKP----------------YKCNECGKAFIERSKLVYHQRNHTGE- 859
Query: 957 KHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMH 1010
K Y C CG+ F L +H++ HS C C S +H H
Sbjct: 860 KPYKCIECGKAFGRFSCLNKHQMIHSGE-KPYKCNECGKSFISRSGLTKHQTKH 912
Score = 169 bits (427), Expect = 2e-41
Identities = 171/718 (23%), Positives = 257/718 (35%), Gaps = 170/718 (23%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + CD C +VF S++ H +
Sbjct: 355 EKPYQCDICGKVFRQNSNLVNH-------------------------------------Q 377
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C C KSFS+ S L H+ HS P+KC C + FK S
Sbjct: 378 RIHTGEK------PYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTT 431
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H +HTG+K Y C CD FS+ L H ++HT KPYKC C + F +S L GH ++
Sbjct: 432 HQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRI 491
Query: 224 HERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQC 283
H K KC +C + F Q + H E R QC
Sbjct: 492 HTGEK----------------PYKCDKCGKAFK-----QGSLLTRHKIIHTREKR--YQC 528
Query: 284 VYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHS 341
C ++F E + L+ H+ ++H+GE+ C++C + F+ L H H ++P CN
Sbjct: 529 GECGKVFSENSCLVRHL-RIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNEC 587
Query: 342 NSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQA 401
+ V Y+ + A+ TG +
Sbjct: 588 GT---VFRNYSCL--------------------------------ARHLRIHTGQKPYKC 612
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
V C K +F+ L H + +KP Q C C +V S Y+ +++H
Sbjct: 613 NV------CGK-VFNDSGNLSNHKRIHTGEKPFQ---CNECGKVF-SYYSCLARHRKIHT 661
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+CN C + ++L +H+ G + C
Sbjct: 662 GEKP-----------YKCNDCGKAYTQRSSLTKHLIIHTG--------EKPYNCNEFGGA 702
Query: 522 FLTDSSLEEHIRQ---------VHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFN 572
F+ S L + R HC + S + Y C C +FN
Sbjct: 703 FIQSSKLARYHRNPTGEKPHKCSHCGRTFSHITGLTYHQRRHTGEMPYKCIEC--GQVFN 760
Query: 573 SVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTG 632
S L +H + IH G+K + V Q++L +++ TG
Sbjct: 761 STSNLARHRR------------IHTGEKPYKCNECGKVFRHQSTLARHRSI------HTG 802
Query: 633 E--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMIT 690
E Y+CN+CG + H K H T C +C K F + L+ H H
Sbjct: 803 EKPYVCNECGKAFRVRSILVNHQKMH--TGDKPYKCNECGKAFIERSKLVYHQRNH--TG 858
Query: 691 STYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNE 748
Y C C K F L KH + ++C C + F S+ + H KH+ E
Sbjct: 859 EKPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECGKSFISRSGLTKH-QTKHTAE 915
Score = 154 bits (389), Expect = 5e-37
Identities = 190/826 (23%), Positives = 285/826 (34%), Gaps = 155/826 (18%)
Query: 293 ETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSP----SL 346
+ SL +E+ H EK C C ++F L +H H ++P CN SL
Sbjct: 201 QLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSL 260
Query: 347 VTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYS 406
+T+ + P K Q + + S + Y
Sbjct: 261 LTI-----------------HQIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYK 303
Query: 407 CIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPG 466
C C K FS L IH + +KP + C C + L H + +H + P
Sbjct: 304 CNECGKS-FSQSYNLAIHQRIHTGEKPYK---CNECGKTFKQGSCLTTH-QIIHTGEKP- 357
Query: 467 LIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDS 526
YQC+ C +V + L H R G + C C F S
Sbjct: 358 ----------YQCDICGKVFRQNSNLVNHQRIHTG--------EKPYKCNICGKSFSQSS 399
Query: 527 SLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHK 586
+L H + VH SG++ Y C C + F L H
Sbjct: 400 NLATH-QTVH---SGNK---------------PYKCDECGKT--FKRSSSLTTH------ 432
Query: 587 NIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYT 644
IH G+K V +++ L Q TGE Y CN+CG ++
Sbjct: 433 ------QIIHTGEKPYTCDVCDKVFSQRSQLARHQR------SHTGEKPYKCNECGKVFS 480
Query: 645 SLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFT 704
H + H T C +C K F L +H IH Y C C K F+
Sbjct: 481 QTSHLVGHRRIH--TGEKPYKCDKCGKAFKQGSLLTRHKIIH--TREKRYQCGECGKVFS 536
Query: 705 SVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNE 764
L +HL ++C +C +VF+ ++ +H + H+ EK ++C C FRN
Sbjct: 537 ENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRI-HTGEKP-FQCNECGTVFRNY 594
Query: 765 TDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAII 822
+ L H++ + K +KC CG+ F L H I T K + C C K F
Sbjct: 595 SCLARHLR---IHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYS 651
Query: 823 LLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTS 882
L +H + K +CG Q+ + ++ ++ +N ++ + +S
Sbjct: 652 CLARHRKIHTGEKPYKCNDCG----KAYTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSS 707
Query: 883 -----------EPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYK 931
E + C CG ++ T L HQ R P YK
Sbjct: 708 KLARYHRNPTGEKPHKCSHCGRTFSHITGLTYHQRRHTGEMP----------------YK 751
Query: 932 CNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN-- 989
C C + F S + L H + H G K Y C CG+ F TL H+ H TG
Sbjct: 752 CIECGQVFNSTSNLARHRRIHTGE-KPYKCNECGKVFRHQSTLARHRSIH-----TGEKP 805
Query: 990 --CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKT- 1046
C C + + H +MH + ++C C + +L H H +
Sbjct: 806 YVCNECGKAFRVRSILVNHQKMHTGDKP----YKCNECGKAFIERSKLVYHQRNHTGEKP 861
Query: 1047 ----------GNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK 1082
G S + +K YKC C K F S+ L K
Sbjct: 862 YKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECGKSFISRSGLTK 907
Score = 152 bits (385), Expect = 2e-36
Identities = 169/703 (24%), Positives = 248/703 (35%), Gaps = 87/703 (12%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y C CG + H ++H T C +C K F +L H IH
Sbjct: 274 YQCGVCGKIFRQNSDLVNHRRSH--TGEKPYKCNECGKSFSQSYNLAIHQRIH--TGEKP 329
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y C C K F L H + ++C +C +VF ++ H + H+ EK Y+
Sbjct: 330 YKCNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNLVNHQRI-HTGEKP-YK 387
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNC 811
C C F ++L H + + K +KC CG++F L H I T K Y C
Sbjct: 388 CNICGKSFSQSSNL---ATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPYTC 444
Query: 812 KFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNS 871
C K F L +H R K CG S S
Sbjct: 445 DVCDKVFSQRSQLARHQRSHTGEKPYKCNECG---------------------KVFSQTS 483
Query: 872 HDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQL---RDHNIRPGESAIVKKKAELIKG 928
H + T E Y CD CG A+ +LL H++ R+ + GE V + +
Sbjct: 484 HLVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVR 543
Query: 929 N---------YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKV 979
+ YKCNVC + F L H + H G K + C CG F + L H
Sbjct: 544 HLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGE-KPFQCNECGTVFRNYSCLARHLR 602
Query: 980 THSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHG 1039
H+ C +C H ++H + F+C C + + L H
Sbjct: 603 IHTGQKPY-KCNVCGKVFNDSGNLSNHKRIHTGEKP----FQCNECGKVFSYYSCLARHR 657
Query: 1040 TFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCA-G 1095
H TG +K YKC C K + + L K + PY G
Sbjct: 658 KIH------------TG-----EKPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFG 700
Query: 1096 CVNLSKSASPGINVPPGTNRPGLGQN--ENLSAIEG-----KGKVGGLKTRCSSCNVKFE 1148
+ S + P +P + S I G + G + +C C F
Sbjct: 701 GAFIQSSKLARYHRNPTGEKPHKCSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFN 760
Query: 1149 SESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEW 1208
S S L H + E N S + R + EK Y C +C F
Sbjct: 761 STSNLARHRRIHTGEKPYKCNECGKVFRHQSTLARHRSIHTGEKP-YVCNECGKAFRVRS 819
Query: 1209 DIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQA 1268
+ H H D+ ++C C + F +KL H H+ E +KC C F +
Sbjct: 820 ILVNHQKMHTGDKP--YKCNECGKAFIERSKLVYHQRNHTGEK---PYKCIECGKAFGRF 874
Query: 1269 NKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS 1311
+ L +H G+ K Y C +C + F ++ L H T+H++
Sbjct: 875 SCLNKHQMIHSGE--KPYKCNECGKSFISRSGLTKH-QTKHTA 914
Score = 142 bits (357), Expect = 3e-33
Identities = 181/787 (22%), Positives = 270/787 (34%), Gaps = 164/787 (20%)
Query: 584 NHKNIPLALNYIHNGKKSR-ALSPLSPVAIEQ----------TSLKMMQAVGGAPARPTG 632
N+K +P+ NGK+ + + + IE T L+ Q G
Sbjct: 108 NYKEVPMTYKNNLNGKRGQHSQEDVENKCIENQLTLSFQSRLTELQKFQTEGKI------ 161
Query: 633 EYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITST 692
Y CNQ + + L + L +LP + +K++ N+ +++ + T
Sbjct: 162 -YECNQSEKTVNN-----SSLVSPLQRILPSVQT-NISKKYENE---FLQLSLPTQLEKT 211
Query: 693 Y-----YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSN 747
+ Y+C+ C K F L H + T ++C C + F + +H V
Sbjct: 212 HIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVH--T 269
Query: 748 EKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTH 805
K Y+C C FR +DL V H K +KC CG+SF L H I T
Sbjct: 270 RGKPYQCGVCGKIFRQNSDL---VNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTG 326
Query: 806 SKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNS 865
K Y C C K F K +C LT
Sbjct: 327 EKPYKCNECGKTF-------------------KQGSC-------------------LTTH 348
Query: 866 QESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAEL 925
Q H T E Y CDICG + + L NHQ I GE
Sbjct: 349 QIIH-----------TGEKPYQCDICGKVFRQNSNLVNHQ----RIHTGEKP-------- 385
Query: 926 IKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSL 985
YKCN+C ++F + L H H G K Y C CG+ F +LT H++ H+
Sbjct: 386 ----YKCNICGKSFSQSSNLATHQTVHSGN-KPYKCDECGKTFKRSSSLTTHQIIHTGE- 439
Query: 986 DTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFH--- 1042
C +C + H + H + ++C C + + T L H H
Sbjct: 440 KPYTCDVCDKVFSQRSQLARHQRSHTGEK----PYKCNECGKVFSQTSHLVGHRRIHTGE 495
Query: 1043 ----MQKTGNG---SAVQTTGRGQHV-QKLYKCASCLKEFRSKQDLV---KLDINGLPY- 1090
K G ++ T + H +K Y+C C K F LV ++ PY
Sbjct: 496 KPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYK 555
Query: 1091 -GLCAGCVNLSKSASPGINVPPG-----TNRPG-LGQNENLSAIEGKGKVGGLKTRCSSC 1143
+C N S + S + G N G + +N + A + G +C+ C
Sbjct: 556 CNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTGQKPYKCNVC 615
Query: 1144 NVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMV 1203
F L NH + E N S + R + E K Y+C C
Sbjct: 616 GKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARHRKIHTGE-KPYKCNDCGKA 674
Query: 1204 FYNEWDIQVHVANHMIDEGLN--------------------------HECKLCSQTFDSP 1237
+ + H+ H ++ N H+C C +TF
Sbjct: 675 YTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCSHCGRTFSHI 734
Query: 1238 AKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFF 1297
L H H+ E +KC C VF + L +H G +K Y C +C + F
Sbjct: 735 TGLTYHQRRHTGE---MPYKCIECGQVFNSTSNLARHRRIHTG--EKPYKCNECGKVFRH 789
Query: 1298 QTELQNH 1304
Q+ L H
Sbjct: 790 QSTLARH 796
Score = 141 bits (356), Expect = 4e-33
Identities = 191/859 (22%), Positives = 303/859 (35%), Gaps = 144/859 (16%)
Query: 449 LYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLN--TLQEHIRCSHGFANPA 506
+Y N+ K V+ + + +P++ Q N + N+ +L + +H P
Sbjct: 161 IYECNQSEKTVNNSSLVSPLQRILPSV--QTNISKKYENEFLQLSLPTQLEKTHIREKP- 217
Query: 507 AKDSNAFFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFGSPVLGTPKEPVV-- 557
+ C C F SSL H + VH C+ G F L T + V
Sbjct: 218 ------YMCKGCGKAFRVSSSLINH-QMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTR 270
Query: 558 -EVYSCSYC-----TNSPIFN--------SVLKLNKHIKENHKNIPLALNY-IHNGKKSR 602
+ Y C C NS + N K N+ K ++ LA++ IH G+K
Sbjct: 271 GKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEKPY 330
Query: 603 ALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTV 660
+ + + L Q + TGE Y C+ CG + + H + H T
Sbjct: 331 KCNECGKTFKQGSCLTTHQIIH------TGEKPYQCDICGKVFRQNSNLVNHQRIH--TG 382
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C C K F +L H T+H + Y C+ C K F L H +
Sbjct: 383 EKPYKCNICGKSFSQSSNLATHQTVHS--GNKPYKCDECGKTFKRSSSLTTHQIIHTGEK 440
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
+ C +C +VF + + H H+ EK Y+C C F + L V H +
Sbjct: 441 PYTCDVCDKVFSQRSQLARHQR-SHTGEKP-YKCNECGKVFSQTSHL---VGHRRIHTGE 495
Query: 781 KVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETK 838
K +KC CG++F L H I T K+Y C C K F L +HLR
Sbjct: 496 KPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLR--------- 546
Query: 839 TPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTME 898
+ E + + +++ + + + T E + C+ CG +
Sbjct: 547 ------------IHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNY 594
Query: 899 TLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKH 958
+ L H LR H G+ YKCNVC + F L H + H G K
Sbjct: 595 SCLARH-LRIHT---GQKP------------YKCNVCGKVFNDSGNLSNHKRIHTGE-KP 637
Query: 959 YMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLT 1018
+ C CG+ F L H+ H+ C C +H +H T
Sbjct: 638 FQCNECGKVFSYYSCLARHRKIHTGEKPY-KCNDCGKAYTQRSSLTKHLIIH-------T 689
Query: 1019 GFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQ 1078
G + C + + ++ +H TG +K +KC+ C + F
Sbjct: 690 GEKPYNCNEFGGAFIQSSKLARYHRNPTG--------------EKPHKCSHCGRTFSHIT 735
Query: 1079 DLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGG 1135
L + +PY C C + S S L ++ + G
Sbjct: 736 GLTYHQRRHTGEMPYK-CIECGQVFNSTS------------NLARHRRIHT-------GE 775
Query: 1136 LKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTY 1195
+C+ C F +S L H ++IH P + K +V + K Y
Sbjct: 776 KPYKCNECGKVFRHQSTLARH-RSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPY 834
Query: 1196 QCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGT 1255
+C +C F + H NH ++ ++C C + F + L H + HS E
Sbjct: 835 KCNECGKAFIERSKLVYHQRNHTGEK--PYKCIECGKAFGRFSCLNKHQMIHSGE---KP 889
Query: 1256 FKCPVCFTVFVQANKLQQH 1274
+KC C F+ + L +H
Sbjct: 890 YKCNECGKSFISRSGLTKH 908
>gi|23308729 zinc finger protein 268 [Homo sapiens]
Length = 947
Score = 204 bits (518), Expect = 6e-52
Identities = 208/841 (24%), Positives = 307/841 (36%), Gaps = 176/841 (20%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
P+ C C+K+FS SYL H+Q+H+++ P+ C C + F K H ++HTG+K + C
Sbjct: 275 PFGCSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKDFSSKSYLIVHQRIHTGEKLHEC 334
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
SEC FS L IH + HT PY+C C + F L H + H K
Sbjct: 335 SECRKTFSFHSQLVIHQRIHTGENPYECCECGKVFSRKDQLVSHQKTHSGQK-------- 386
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
C++C + F L H H P E C C + F +++L
Sbjct: 387 --------PYVCNECGKAFGLKSQLIIH-ERIHTGEKPYE------CNECQKAFNTKSNL 431
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQ--QPESCNHSNSPSLVTVGYTSV 354
M H ++ H+GEK CS C ++F +L H H +P C G++
Sbjct: 432 MVH-QRTHTGEKPYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGCIQCGK------GFSL- 483
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
S L V + P + G K ++ + + + + C C K
Sbjct: 484 -----KSQLIVHQRSHTGMKPYVCNECG-KAFRSKSYLIIHTRTHTGEKLHECNNCGK-A 536
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
FS + L IH + E + C C + Y L H ++ H + P
Sbjct: 537 FSFKSQLIIH---QRIHTGENPYECHECGKAFSRKYQLISH-QRTHAGEKP--------- 583
Query: 475 IVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQ 534
Y+C C + + L H R G F C C F T S+L H R
Sbjct: 584 --YECTDCGKAFGLKSQLIIHQRTHTG--------EKPFECSECQKAFNTKSNLIVHQR- 632
Query: 535 VHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNY 594
T ++P YSC+ C + F S L ++K
Sbjct: 633 --------------THTGEKP----YSCNECGKAFTFKSQLIVHKG-------------- 660
Query: 595 IHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLK 654
+H G K S + + SLK V Y C++CG + S H++
Sbjct: 661 VHTGVKPYGCSQCA----KTFSLKSQLIVHQRSHTGVKPYGCSECGKAFRSKSYLIIHMR 716
Query: 655 THLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLL 714
TH T C +C K F L+ H IH Y C C K F D L H
Sbjct: 717 TH--TGEKPHECRECGKSFSFNSQLIVHQRIH--TGENPYECSECGKAFNRKDQLISHQR 772
Query: 715 DMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHN 774
+ C+ C + F SK + +H+ HS EK Y C C F ++ L +H + +
Sbjct: 773 THAGEKPYGCSECGKAFSSKSYLIIHMRT-HSGEKP-YECNECGKAFIWKSLLIVHERTH 830
Query: 775 HLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKH 832
N +KC C +SF ++ L H + T K Y C C KAF +R
Sbjct: 831 AGVNP---YKCSQCEKSFSGKLRLLVHQRMHTREKPYECSECGKAF---------IRNSQ 878
Query: 833 CVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICG 892
+ +T H G E YGC+ CG
Sbjct: 879 LIVHQRT--------------------------------HSG--------EKPYGCNECG 898
Query: 893 AAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTH 952
++ +++L HQ R H GE KC C + F ++ L H +TH
Sbjct: 899 KTFSQKSILSAHQ-RTHT---GEKPC------------KCTECGKAFCWKSQLIMHQRTH 942
Query: 953 L 953
+
Sbjct: 943 V 943
Score = 153 bits (387), Expect = 9e-37
Identities = 167/682 (24%), Positives = 257/682 (37%), Gaps = 133/682 (19%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E +H C C + F S + H+ ++ G E+ C S KDQ SH
Sbjct: 329 EKLHECSECRKTFSFHSQLVIHQ----RIHTG---ENPYECCECGKVFSRKDQLV-SH-- 378
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
++ PY C C K+F S L HE+ H+ + P++C C + F K +
Sbjct: 379 -----QKTHSGQKPYVCNECGKAFGLKSQLIIHERIHTGEKPYECNECQKAFNTKSNLMV 433
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H + HTG+K Y CS+C AF+ L +H HT KPY C C +GF SL + V
Sbjct: 434 HQRTHTGEKPYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGCIQCGKGF----SLKSQLIV 489
Query: 224 HERNKDGSQ--------SGSRMEDWKMKDTQ--------KCSQCEEGFDFPEDLQKHIA- 266
H+R+ G + R + + + T+ +C+ C + F F L H
Sbjct: 490 HQRSHTGMKPYVCNECGKAFRSKSYLIIHTRTHTGEKLHECNNCGKAFSFKSQLIIHQRI 549
Query: 267 -------ECHPECSPNEDRA--------------ALQCVYCHELFVEETSLMNHMEQVHS 305
ECH EC R +C C + F ++ L+ H ++ H+
Sbjct: 550 HTGENPYECH-ECGKAFSRKYQLISHQRTHAGEKPYECTDCGKAFGLKSQLIIH-QRTHT 607
Query: 306 GEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNL 363
GEK CS C ++F+T L H +H ++P SCN + T S L
Sbjct: 608 GEKPFECSECQKAFNTKSNLIVHQRTHTGEKPYSCNECGK------------AFTFKSQL 655
Query: 364 SVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQI 423
V P S+ K + ++ + S Y C C K F S + L I
Sbjct: 656 IVHKGVHT-GVKPYGCSQCAKTFSLKSQLIVHQRSHTGVKPYGCSECGKA-FRSKSYLII 713
Query: 424 HLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCS 483
H++T +KP H C+ C + L H +++H ++P Y+C+ C
Sbjct: 714 HMRTHTGEKP---HECRECGKSFSFNSQLIVH-QRIHTGENP-----------YECSECG 758
Query: 484 EVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQ------VHC 537
+ N + L H R G + C C F + S L H+R C
Sbjct: 759 KAFNRKDQLISHQRTHAG--------EKPYGCSECGKAFSSKSYLIIHMRTHSGEKPYEC 810
Query: 538 DLSGSRFGSPVLGTPKEPV---VEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIP----- 589
+ G F L E V Y CS C S F+ L+L H + + + P
Sbjct: 811 NECGKAFIWKSLLIVHERTHAGVNPYKCSQCEKS--FSGKLRLLVHQRMHTREKPYECSE 868
Query: 590 -----------LALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAV--GGAPARPTGEYIC 636
+ H+G+K + +++ L Q G P + C
Sbjct: 869 CGKAFIRNSQLIVHQRTHSGEKPYGCNECGKTFSQKSILSAHQRTHTGEKPCK------C 922
Query: 637 NQCGAKYTSLDSFQTHLKTHLD 658
+CG + H +TH+D
Sbjct: 923 TECGKAFCWKSQLIMHQRTHVD 944
Score = 150 bits (378), Expect = 1e-35
Identities = 167/706 (23%), Positives = 266/706 (37%), Gaps = 100/706 (14%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y CN+CG ++S H + H L + C +C K F L+ H IH
Sbjct: 304 YGCNECGKDFSSKSYLIVHQRIHTGEKLHE--CSECRKTFSFHSQLVIHQRIH--TGENP 359
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y C C K F+ D L H + C C + F K + +H + H+ EK Y
Sbjct: 360 YECCECGKVFSRKDQLVSHQKTHSGQKPYVCNECGKAFGLKSQLIIHERI-HTGEKP-YE 417
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNC 811
C C F +++L +H + + E K + C CG++F + +L H H+ K Y C
Sbjct: 418 CNECQKAFNTKSNLMVHQRTHTGE---KPYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGC 474
Query: 812 KFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNS 871
C K F L H R + CG S K + + T ++ H
Sbjct: 475 IQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKAFRS----KSYLIIHTRTHTGEKLHEC 530
Query: 872 HDGSE-----------EDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGE----- 915
++ + + + T E Y C CG A++ + L +HQ +P E
Sbjct: 531 NNCGKAFSFKSQLIIHQRIHTGENPYECHECGKAFSRKYQLISHQRTHAGEKPYECTDCG 590
Query: 916 -------SAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERF 968
I+ ++ + ++C+ C + F +++ L H +TH G K Y C CG+ F
Sbjct: 591 KAFGLKSQLIIHQRTHTGEKPFECSECQKAFNTKSNLIVHQRTHTGE-KPYSCNECGKAF 649
Query: 969 PSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQT 1028
L HK H+ G C C + + + H + H ++ + C C +
Sbjct: 650 TFKSQLIVHKGVHTGVKPYG-CSQCAKTFSLKSQLIVHQRSHTGVK----PYGCSECGKA 704
Query: 1029 VTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDI 1085
S L IH H TG +K ++C C K F L+ ++
Sbjct: 705 FRSKSYLIIHMRTH---TG--------------EKPHECRECGKSFSFNSQLIVHQRIHT 747
Query: 1086 NGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKT-RCSSCN 1144
PY C+ C G N I + G K CS C
Sbjct: 748 GENPYE-CSEC--------------------GKAFNRKDQLISHQRTHAGEKPYGCSECG 786
Query: 1145 VKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVF 1204
F S+S L H++T E + N K + + Y+C +C+ F
Sbjct: 787 KAFSSKSYLIIHMRTHSGEKPYECNECG-KAFIWKSLLIVHERTHAGVNPYKCSQCEKSF 845
Query: 1205 YNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTV 1264
+ + VH H ++ +EC C + F ++L H HS E G +C F+
Sbjct: 846 SGKLRLLVHQRMHTREK--PYECSECGKAFIRNSQLIVHQRTHSGEKPYGCNECGKTFS- 902
Query: 1265 FVQANKLQQHIFSAHGQE---DKIYDCTQCPQKFFFQTELQNHTMT 1307
Q+ I SAH + +K CT+C + F ++++L H T
Sbjct: 903 -------QKSILSAHQRTHTGEKPCKCTECGKAFCWKSQLIMHQRT 941
Score = 135 bits (341), Expect = 2e-31
Identities = 169/737 (22%), Positives = 263/737 (35%), Gaps = 117/737 (15%)
Query: 301 EQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTT 358
+Q++ GEK CS C ++F + L H +H ++P CN ++S S
Sbjct: 267 QQMYMGEKPFGCSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKD------FSSKSYLI 320
Query: 359 PDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSL 418
+ S RK + + + + Y C C K +FS
Sbjct: 321 VHQRIHTGEKLH-------ECSECRKTFSFHSQLVIHQRIHTGENPYECCECGK-VFSRK 372
Query: 419 AVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQ 478
L H KT KP ++C C + L H +++H + P Y+
Sbjct: 373 DQLVSHQKTHSGQKP---YVCNECGKAFGLKSQLIIH-ERIHTGEKP-----------YE 417
Query: 479 CNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFF--------------------CPHC 518
CN C + N + L H R G D F C C
Sbjct: 418 CNECQKAFNTKSNLMVHQRTHTGEKPYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGCIQC 477
Query: 519 YMGFLTDSSLEEHIRQ------VHCDLSGSRFGSP---VLGTPKEPVVEVYSCSYCTNSP 569
GF S L H R C+ G F S ++ T +++ C+ C +
Sbjct: 478 GKGFSLKSQLIVHQRSHTGMKPYVCNECGKAFRSKSYLIIHTRTHTGEKLHECNNCGKAF 537
Query: 570 IFNSVLKLNK--HIKEN------------HKNIPLALNYIHNGKKSRALSPLSPVAIEQT 615
F S L +++ H EN K ++ H G+K + ++
Sbjct: 538 SFKSQLIIHQRIHTGENPYECHECGKAFSRKYQLISHQRTHAGEKPYECTDCGKAFGLKS 597
Query: 616 SLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEF 673
L + Q TGE + C++C + + + H +TH T +C +C K F
Sbjct: 598 QLIIHQRTH------TGEKPFECSECQKAFNTKSNLIVHQRTH--TGEKPYSCNECGKAF 649
Query: 674 PNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDS 733
+ L+ H +H + Y C C K F+ L H + C+ C + F S
Sbjct: 650 TFKSQLIVHKGVHTGVKP--YGCSQCAKTFSLKSQLIVHQRSHTGVKPYGCSECGKAFRS 707
Query: 734 KVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFG 793
K + +H+ H+ EK + C C F + L +H + + EN ++C CG++F
Sbjct: 708 KSYLIIHMRT-HTGEKP-HECRECGKSFSFNSQLIVHQRIHTGENP---YECSECGKAFN 762
Query: 794 TEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTN--GASE 849
+ +L H TH+ K Y C C KAF + L H+R + CG S
Sbjct: 763 RKDQLISHQRTHAGEKPYGCSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKAFIWKSL 822
Query: 850 QVQKEEVELQTLLTNSQESHNSHDGS-----EEDVDTSEPMYGCDICGAAYTMETLLQNH 904
+ E + S G + + T E Y C CG A+ + L H
Sbjct: 823 LIVHERTHAGVNPYKCSQCEKSFSGKLRLLVHQRMHTREKPYECSECGKAFIRNSQLIVH 882
Query: 905 QLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPIC 964
Q +P Y CN C +TF ++ L H +TH G K C C
Sbjct: 883 QRTHSGEKP----------------YGCNECGKTFSQKSILSAHQRTHTGE-KPCKCTEC 925
Query: 965 GERFPSLLTLTEHKVTH 981
G+ F L H+ TH
Sbjct: 926 GKAFCWKSQLIMHQRTH 942
Score = 117 bits (292), Expect = 9e-26
Identities = 138/611 (22%), Positives = 232/611 (37%), Gaps = 110/611 (18%)
Query: 722 FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGK 781
F C+ C++ F SK + +H H+ EK Y C C DF +++ L + H + K
Sbjct: 276 FGCSCCEKAFSSKSYLLVHQQT-HAEEKP-YGCNECGKDFSSKSYL---IVHQRIHTGEK 330
Query: 782 VHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKT 839
+H+C C ++F +L H I T Y C C K F
Sbjct: 331 LHECSECRKTFSFHSQLVIHQRIHTGENPYECCECGKVFS-------------------- 370
Query: 840 PNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMET 899
+K++ L + Q++H+ + Y C+ CG A+ +++
Sbjct: 371 ------------RKDQ------LVSHQKTHSG-----------QKPYVCNECGKAFGLKS 401
Query: 900 LLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHY 959
L H+ I GE Y+CN C + F +++ L H +TH G K Y
Sbjct: 402 QLIIHE----RIHTGEKP------------YECNECQKAFNTKSNLMVHQRTHTGE-KPY 444
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTG 1019
+C CG+ F L H+ H+ G C C + + + H + H ++
Sbjct: 445 VCSDCGKAFTFKSQLIVHQGIHTGVKPYG-CIQCGKGFSLKSQLIVHQRSHTGMK----P 499
Query: 1020 FRCVVCMQTVTSTLELKIHGTFH----MQKTGN-GSAVQTTGRGQHVQKL------YKCA 1068
+ C C + S L IH H + + N G A + Q++ Y+C
Sbjct: 500 YVCNECGKAFRSKSYLIIHTRTHTGEKLHECNNCGKAFSFKSQLIIHQRIHTGENPYECH 559
Query: 1069 SCLKEFRSKQDLV---KLDINGLPYGLCAGCVN-LSKSASPGINVPPGTNRPGLGQNENL 1124
C K F K L+ + PY C C + I+ T +E
Sbjct: 560 ECGKAFSRKYQLISHQRTHAGEKPYE-CTDCGKAFGLKSQLIIHQRTHTGEKPFECSECQ 618
Query: 1125 SAIEGKGKV--------GGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTP 1176
A K + G C+ C F +S+L H + +H + P S KT
Sbjct: 619 KAFNTKSNLIVHQRTHTGEKPYSCNECGKAFTFKSQLIVH-KGVHTGVKPYGCSQCAKTF 677
Query: 1177 QVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDS 1236
+ + K Y C +C F ++ + +H+ H ++ HEC+ C ++F
Sbjct: 678 SLKSQLIVHQRSHTGVKPYGCSECGKAFRSKSYLIIHMRTHTGEK--PHECRECGKSFSF 735
Query: 1237 PAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFF 1296
++L H H+ E ++C C F + ++L H + G +K Y C++C + F
Sbjct: 736 NSQLIVHQRIHTGE---NPYECSECGKAFNRKDQLISHQRTHAG--EKPYGCSECGKAFS 790
Query: 1297 FQTELQNHTMT 1307
++ L H T
Sbjct: 791 SKSYLIIHMRT 801
Score = 90.5 bits (223), Expect = 9e-18
Identities = 41/112 (36%), Positives = 59/112 (52%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C+KSFS L H++ H+ + P++C+ C + F H + H+G+K Y C
Sbjct: 835 PYKCSQCEKSFSGKLRLLVHQRMHTREKPYECSECGKAFIRNSQLIVHQRTHSGEKPYGC 894
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNK 228
+EC FS+ L H +THT KP KC C + F S L H + H +K
Sbjct: 895 NECGKTFSQKSILSAHQRTHTGEKPCKCTECGKAFCWKSQLIMHQRTHVDDK 946
>gi|40217792 zinc finger protein 585A [Homo sapiens]
Length = 714
Score = 203 bits (516), Expect = 1e-51
Identities = 179/740 (24%), Positives = 282/740 (38%), Gaps = 135/740 (18%)
Query: 123 CDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAA 182
C K S ++ + + ++C ++F K H+K+ G+K Y C EC A
Sbjct: 52 CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111
Query: 183 FSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKM 242
F + IH KTH KP+KC C + F SSL H ++H K
Sbjct: 112 FVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEK-------------- 157
Query: 243 KDTQKCSQCEEGFDFPEDL----QKHIAECHPECSP-----------------NEDRAAL 281
+CSQC +GF + DL + H E H EC+ + +
Sbjct: 158 --LYECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSY 215
Query: 282 QCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQ--QPESCN 339
C+ C + F+++T L+ H ++H+GEK CS C +SF + +L H H +P C
Sbjct: 216 ICIECGQAFIQKTHLIAH-RRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICT 274
Query: 340 H-----SNSPSLVTVGYTSVSSTTPDSNLS------------VDSSTMVEAAPPIPKSRG 382
SN+ +LVT + V S S + + + P S
Sbjct: 275 EYGKVFSNNSNLVT--HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDC 332
Query: 383 RKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYC 442
K Q++ + +Y C+ C ++ + + E+ H C +C
Sbjct: 333 GKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQI----IHTGEKPHKCGHC 388
Query: 443 LEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGF 502
++ S L+ H K++H + P Y CN C + + + L H + G
Sbjct: 389 GKLFTSKSQLHVH-KRIHTGEKP-----------YMCNKCGKAFTNRSNLITHQKTHTG- 435
Query: 503 ANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSC 562
++ C C F S L H R + T ++P Y C
Sbjct: 436 -------EKSYICSKCGKAFTQRSDLITHQR---------------IHTGEKP----YEC 469
Query: 563 SYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQA 622
+ C + F LN H K IH G++ +++ L + Q
Sbjct: 470 NTCGKA--FTQKSHLNIHQK------------IHTGERQYECHECGKAFNQKSILIVHQK 515
Query: 623 VGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLL 680
+ TGE Y+C +CG + +F TH + H T C C K F ++ LL
Sbjct: 516 I------HTGEKPYVCTECGRAFIRKSNFITHQRIH--TGEKPYECSDCGKSFTSKSQLL 567
Query: 681 KHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLH 740
H +H Y+C C K F+ +L KH + C+ C + F K + H
Sbjct: 568 VHQPVH--TGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH 625
Query: 741 LAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQC 800
+ H+ EK Y C+ C F ++ LQ+ H + K + C CG++F L
Sbjct: 626 HRI-HTGEKP-YECSDCGKSFTKKSQLQV---HQRIHTGEKPYVCAECGKAFTDRSNLNK 680
Query: 801 HITTHS--KKYNCKFCSKAF 818
H TTH+ K Y C C K F
Sbjct: 681 HQTTHTGDKPYKCGICGKGF 700
Score = 183 bits (464), Expect = 1e-45
Identities = 162/639 (25%), Positives = 248/639 (38%), Gaps = 104/639 (16%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C C K FS S L HE+ H+ + +CT C + F K + H K+HTG++ Y C
Sbjct: 159 YECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICI 218
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHER---------NK 228
EC AF + HL H + HT KPY+C+ C + F+S S L H +VH R K
Sbjct: 219 ECGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGK 278
Query: 229 DGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVY 285
S + + + K++ +K C++C + F + +L H H P E C
Sbjct: 279 VFSNNSNLVTHKKVQSREKSSICTECGKAFTYRSELIIH-QRIHTGEKPYE------CSD 331
Query: 286 CHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNS 343
C + F ++++L H +++H+GEK C C +F L +H H ++P C H
Sbjct: 332 CGKAFTQKSALTVH-QRIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCG- 389
Query: 344 PSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKV 403
T S L V P + G K ++ +T + +
Sbjct: 390 -----------KLFTSKSQLHVHKRIHTGEKPYMCNKCG-KAFTNRSNLITHQKTHTGEK 437
Query: 404 TYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQ 463
+Y C C K F+ + L H + +KP + C C + +LN H K +H +
Sbjct: 438 SYICSKCGK-AFTQRSDLITHQRIHTGEKPYE---CNTCGKAFTQKSHLNIHQK-IHTGE 492
Query: 464 DPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFL 523
Y+C+ C + N + L H + G + C C F+
Sbjct: 493 RQ-----------YECHECGKAFNQKSILIVHQKIHTG--------EKPYVCTECGRAFI 533
Query: 524 TDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKE 583
S+ H R + T ++P Y CS C S F S +L H
Sbjct: 534 RKSNFITHQR---------------IHTGEKP----YECSDCGKS--FTSKSQLLVH--- 569
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGA 641
+H G+K + +++L Q TGE YIC++CG
Sbjct: 570 ---------QPVHTGEKPYVCAECGKAFSGRSNLSKHQKT------HTGEKPYICSECGK 614
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDK 701
+ TH + H T C C K F + L H IH Y+C C K
Sbjct: 615 TFRQKSELITHHRIH--TGEKPYECSDCGKSFTKKSQLQVHQRIH--TGEKPYVCAECGK 670
Query: 702 QFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLH 740
FT +L KH ++C +C + F K +H
Sbjct: 671 AFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVH 709
Score = 169 bits (428), Expect = 2e-41
Identities = 184/747 (24%), Positives = 284/747 (38%), Gaps = 120/747 (16%)
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKM-MQAVGGAPARPTGEYICNQCGAK 642
++K + ++ G+K+ + + +++ LK+ ++ + G Y+C +CG
Sbjct: 57 SYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKL-----YVCIECGKA 111
Query: 643 YTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQ 702
+ F H KTH+ C +C K F SL +H IH Y C C K
Sbjct: 112 FVQKPEFIIHQKTHMRE--KPFKCNECGKSFFQVSSLFRHQRIH--TGEKLYECSQCGKG 167
Query: 703 FTSVDDLQKHLLDMHTFV-FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDF 761
F+ DL H +HT CT C + F K ++++H + H+ E+ Y C C F
Sbjct: 168 FSYNSDLSIH-EKIHTGERHHECTDCGKAFTQKSTLKMHQKI-HTGERS-YICIECGQAF 224
Query: 762 RNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFH 819
+T L + H + K ++C CG+SF ++ +LQ H H+ K Y C K F
Sbjct: 225 IQKTHL---IAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFS 281
Query: 820 AIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDV 879
L H K K+ C G + + E + + +
Sbjct: 282 NNSNLVTH---KKVQSREKSSICTECGKAFTYRSELI------------------IHQRI 320
Query: 880 DTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIV--------KKKAELI----- 926
T E Y C CG A+T ++ L HQ I GE + + +KA LI
Sbjct: 321 HTGEKPYECSDCGKAFTQKSALTVHQ----RIHTGEKSYICMKCGLAFIQKAHLIAHQII 376
Query: 927 ---KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSK 983
+ +KC C + F S++ L H + H G K YMC CG+ F + L H+ TH+
Sbjct: 377 HTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGE-KPYMCNKCGKAFTNRSNLITHQKTHTG 435
Query: 984 SLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM 1043
+ C C + + H ++H + + C C + T L IH H
Sbjct: 436 E-KSYICSKCGKAFTQRSDLITHQRIHTGEK----PYECNTCGKAFTQKSHLNIHQKIH- 489
Query: 1044 QKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLS 1100
TG Q Y+C C K F K L+ K+ PY +C C
Sbjct: 490 -----------TGERQ-----YECHECGKAFNQKSILIVHQKIHTGEKPY-VCTECGRAF 532
Query: 1101 KSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTI 1160
S I + G CS C F S+S+L H Q +
Sbjct: 533 IRKSNFIT-------------------HQRIHTGEKPYECSDCGKSFTSKSQLLVH-QPV 572
Query: 1161 HRELVPDSNSTQLKTPQVSPMPRISPSQSDE--KKTYQCIKCQMVFYNEWDIQVHVANHM 1218
H P + K S +S Q +K Y C +C F + ++ H H
Sbjct: 573 HTGEKPYVCAECGKA--FSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH---HR 627
Query: 1219 IDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFS 1277
I G +EC C ++F ++LQ H H+ E + C C F + L +H +
Sbjct: 628 IHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGE---KPYVCAECGKAFTDRSNLNKHQTT 684
Query: 1278 AHGQEDKIYDCTQCPQKFFFQTELQNH 1304
G DK Y C C + F ++ H
Sbjct: 685 HTG--DKPYKCGICGKGFVQKSVFSVH 709
Score = 161 bits (408), Expect = 3e-39
Identities = 173/716 (24%), Positives = 276/716 (38%), Gaps = 148/716 (20%)
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C K +F+ + L++HLK + E+ ++C C + H K H +
Sbjct: 75 YECAKFEK-IFTQKSQLKVHLKVL---AGEKLYVCIECGKAFVQKPEFIIHQK-THMREK 129
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLT 524
P ++CN C + +++L H R G + C C GF
Sbjct: 130 P-----------FKCNECGKSFFQVSSLFRHQRIHTG--------EKLYECSQCGKGFSY 170
Query: 525 DSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKEN 584
+S L H ++H +G R + C+ C + S LK+++ I
Sbjct: 171 NSDLSIH-EKIH---TGERH---------------HECTDCGKAFTQKSTLKMHQKI--- 208
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAK 642
H G++S I++T L + + TGE Y C+ CG
Sbjct: 209 -----------HTGERSYICIECGQAFIQKTHLIAHRRIH------TGEKPYECSNCGKS 251
Query: 643 YTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQ 702
+ S Q H + H T + C + K F N +L+ H + S+ IC C K
Sbjct: 252 FISKSQLQVHQRVH--TRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSS--ICTECGKA 307
Query: 703 FTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFR 762
FT +L H + C+ C + F K ++ +H + H+ EK Y C C F
Sbjct: 308 FTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRI-HTGEKS-YICMKCGLAFI 365
Query: 763 NETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF-- 818
+ L + H + K HKC CG+ F ++ +L H I T K Y C C KAF
Sbjct: 366 QKAHL---IAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTN 422
Query: 819 --HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQE--------- 867
+ I + H EK + C G + + + + Q + T +
Sbjct: 423 RSNLITHQKTHTGEKSYI-------CSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKA 475
Query: 868 -SHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKK---KA 923
+ SH + + T E Y C CG A+ +++L HQ I GE V +A
Sbjct: 476 FTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQ----KIHTGEKPYVCTECGRA 531
Query: 924 ELIKGN-------------YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPS 970
+ K N Y+C+ C ++F S++ L H H G K Y+C CG+ F
Sbjct: 532 FIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGE-KPYVCAECGKAFSG 590
Query: 971 LLTLTEHKVTHSKSLDTGN----CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCM 1026
L++H+ TH TG C C + + E + H ++H + + C C
Sbjct: 591 RSNLSKHQKTH-----TGEKPYICSECGKTFRQKSELITHHRIHTGEKP----YECSDCG 641
Query: 1027 QTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK 1082
++ T +L++H H TG +K Y CA C K F + +L K
Sbjct: 642 KSFTKKSQLQVHQRIH------------TG-----EKPYVCAECGKAFTDRSNLNK 680
Score = 160 bits (404), Expect = 1e-38
Identities = 194/842 (23%), Positives = 301/842 (35%), Gaps = 199/842 (23%)
Query: 170 GDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKD 229
G+K + ++C S K + K Y+CA + F S L H++V K
Sbjct: 43 GEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEK- 101
Query: 230 GSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHEL 289
C +C + F +QK H + E +C C +
Sbjct: 102 ---------------LYVCIECGKAF-----VQKPEFIIHQKTHMREK--PFKCNECGKS 139
Query: 290 FVEETSLMNHMEQVHSGEKKNSCSICSESFH-----TVEELYSHMDSHQQPESCNHSNSP 344
F + +SL H +++H+GEK CS C + F ++ E + H + C
Sbjct: 140 FFQVSSLFRH-QRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCG----- 193
Query: 345 SLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVT 404
+ T S L + I G+ Q+T + +
Sbjct: 194 ----------KAFTQKSTLKMHQKIHTGERSYICIECGQA-FIQKTHLIAHRRIHTGEKP 242
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C C K F S + LQ+H + KP +IC +V + NL H K+V +
Sbjct: 243 YECSNCGKS-FISKSQLQVHQRVHTRVKP---YICTEYGKVFSNNSNLVTH-KKVQSREK 297
Query: 465 PGLIVSAMPAIVY-----------------QCNFCSEVVNDLNTLQEHIRCSHGFANPAA 507
+ A Y +C+ C + + L H R G
Sbjct: 298 SSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTG------ 351
Query: 508 KDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTN 567
++ C C + F+ + L H ++ T ++P + C +C
Sbjct: 352 --EKSYICMKCGLAFIQKAHLIAH---------------QIIHTGEKP----HKCGHC-- 388
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+F S +L+ H + IH G+K
Sbjct: 389 GKLFTSKSQLHVHKR------------IHTGEKP-------------------------- 410
Query: 628 ARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
Y+CN+CG +T+ + TH KTH T C +C K F + L+ H IH
Sbjct: 411 ------YMCNKCGKAFTNRSNLITHQKTH--TGEKSYICSKCGKAFTQRSDLITHQRIH- 461
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-----FRCTLCQEVFDSKVSIQLHLA 742
Y C +C K FT QK L++H + + C C + F+ K + +H
Sbjct: 462 -TGEKPYECNTCGKAFT-----QKSHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQK 515
Query: 743 VKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHI 802
+ H+ EK Y CT C F +++ + H + K ++C CG+SF ++ +L H
Sbjct: 516 I-HTGEKP-YVCTECGRAFIRKSNF---ITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQ 570
Query: 803 TTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQT 860
H+ K Y C C KAF L KH + CG QK E
Sbjct: 571 PVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFR----QKSE----- 621
Query: 861 LLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVK 920
L+T+ H H G E Y C CG ++T ++ LQ HQ I GE
Sbjct: 622 LITH----HRIHTG--------EKPYECSDCGKSFTKKSQLQVHQ----RIHTGEKP--- 662
Query: 921 KKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVT 980
Y C C + F + L +H TH G K Y C ICG+ F + H+ +
Sbjct: 663 ---------YVCAECGKAFTDRSNLNKHQTTHTGD-KPYKCGICGKGFVQKSVFSVHQSS 712
Query: 981 HS 982
H+
Sbjct: 713 HA 714
Score = 141 bits (356), Expect = 4e-33
Identities = 99/370 (26%), Positives = 158/370 (42%), Gaps = 55/370 (14%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
P+ C C K F+ S L H++ H+ + P+ C C + F ++ + H K HTG+K Y C
Sbjct: 382 PHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYIC 441
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
S+C AF++ L H + HT KPY+C C + F S L+ H ++H +G R
Sbjct: 442 SKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQKIH--------TGER 493
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+C +C + F+ QK I H + E C C F+ +++
Sbjct: 494 Q--------YECHECGKAFN-----QKSILIVHQKIHTGE--KPYVCTECGRAFIRKSNF 538
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSV 354
+ H +++H+GEK CS C +SF + +L H H ++P C
Sbjct: 539 ITH-QRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECG------------ 585
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
+ + SNLS T P I G K Q++ +T + Y C C K
Sbjct: 586 KAFSGRSNLSKHQKTHTGEKPYICSECG-KTFRQKSELITHHRIHTGEKPYECSDCGKS- 643
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
F+ + LQ+H + +KP ++C C + NLN+H + H P
Sbjct: 644 FTKKSQLQVHQRIHTGEKP---YVCAECGKAFTDRSNLNKH-QTTHTGDKP--------- 690
Query: 475 IVYQCNFCSE 484
Y+C C +
Sbjct: 691 --YKCGICGK 698
Score = 134 bits (337), Expect = 6e-31
Identities = 133/574 (23%), Positives = 219/574 (38%), Gaps = 106/574 (18%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C KSF S L+ H++ H+ P+ CT ++F + + H K+ + +K C
Sbjct: 242 PYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSIC 301
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+EC AF+ L IH + HT KPY+C+ C + F S+L H ++H K
Sbjct: 302 TECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEK-------- 353
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+ C +C F +QK H E +C +C +LF ++ L
Sbjct: 354 --------SYICMKCGLAF-----IQKAHLIAHQIIHTGE--KPHKCGHCGKLFTSKSQL 398
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPES--CNHSNSPSLVTVGYTSV 354
H +++H+GEK C+ C ++F L +H +H +S C+
Sbjct: 399 HVH-KRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCG------------ 445
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
+ T S+L + + P + K Q++ + Y C C K
Sbjct: 446 KAFTQRSDL-ITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQKIHTGERQYECHECGK-A 503
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
F+ ++L +H K +KP ++C C N H +++H + P
Sbjct: 504 FNQKSILIVHQKIHTGEKP---YVCTECGRAFIRKSNFITH-QRIHTGEKP--------- 550
Query: 475 IVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQ 534
Y+C+ C + + L H P + C C F S+L +H ++
Sbjct: 551 --YECSDCGKSFTSKSQLLVH--------QPVHTGEKPYVCAECGKAFSGRSNLSKH-QK 599
Query: 535 VHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNY 594
H T ++P Y CS C + F +L H +
Sbjct: 600 TH--------------TGEKP----YICSECGKT--FRQKSELITH------------HR 627
Query: 595 IHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTH 652
IH G+K S +++ L++ Q + TGE Y+C +CG +T + H
Sbjct: 628 IHTGEKPYECSDCGKSFTKKSQLQVHQRI------HTGEKPYVCAECGKAFTDRSNLNKH 681
Query: 653 LKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIH 686
TH T C C K F + H + H
Sbjct: 682 QTTH--TGDKPYKCGICGKGFVQKSVFSVHQSSH 713
Score = 124 bits (310), Expect = 8e-28
Identities = 83/301 (27%), Positives = 125/301 (41%), Gaps = 35/301 (11%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C C + F SD+ H+ ++ G + TC + S + H
Sbjct: 436 EKSYICSKCGKAFTQRSDLITHQ----RIHTGEKPYECNTCGKAFTQKSHLNIHQKIHT- 490
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE + Y C C K+F++ S L H++ H+ + P+ CT C R F K +
Sbjct: 491 ----GERQ------YECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFIT 540
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H ++HTG+K Y CS+C +F+ L +H HT KPY CA C + F S+L H +
Sbjct: 541 HQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKT 600
Query: 224 H---------ERNKDGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPE 271
H E K Q + ++ +K CS C + F LQ H H
Sbjct: 601 HTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVH-QRIHTG 659
Query: 272 CSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDS 331
P C C + F + ++L H + H+G+K C IC + F H S
Sbjct: 660 EKP------YVCAECGKAFTDRSNLNKH-QTTHTGDKPYKCGICGKGFVQKSVFSVHQSS 712
Query: 332 H 332
H
Sbjct: 713 H 713
>gi|22749331 zinc finger protein 585A [Homo sapiens]
Length = 714
Score = 203 bits (516), Expect = 1e-51
Identities = 179/740 (24%), Positives = 282/740 (38%), Gaps = 135/740 (18%)
Query: 123 CDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAA 182
C K S ++ + + ++C ++F K H+K+ G+K Y C EC A
Sbjct: 52 CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111
Query: 183 FSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKM 242
F + IH KTH KP+KC C + F SSL H ++H K
Sbjct: 112 FVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEK-------------- 157
Query: 243 KDTQKCSQCEEGFDFPEDL----QKHIAECHPECSP-----------------NEDRAAL 281
+CSQC +GF + DL + H E H EC+ + +
Sbjct: 158 --LYECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSY 215
Query: 282 QCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQ--QPESCN 339
C+ C + F+++T L+ H ++H+GEK CS C +SF + +L H H +P C
Sbjct: 216 ICIECGQAFIQKTHLIAH-RRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICT 274
Query: 340 H-----SNSPSLVTVGYTSVSSTTPDSNLS------------VDSSTMVEAAPPIPKSRG 382
SN+ +LVT + V S S + + + P S
Sbjct: 275 EYGKVFSNNSNLVT--HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDC 332
Query: 383 RKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYC 442
K Q++ + +Y C+ C ++ + + E+ H C +C
Sbjct: 333 GKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQI----IHTGEKPHKCGHC 388
Query: 443 LEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGF 502
++ S L+ H K++H + P Y CN C + + + L H + G
Sbjct: 389 GKLFTSKSQLHVH-KRIHTGEKP-----------YMCNKCGKAFTNRSNLITHQKTHTG- 435
Query: 503 ANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSC 562
++ C C F S L H R + T ++P Y C
Sbjct: 436 -------EKSYICSKCGKAFTQRSDLITHQR---------------IHTGEKP----YEC 469
Query: 563 SYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQA 622
+ C + F LN H K IH G++ +++ L + Q
Sbjct: 470 NTCGKA--FTQKSHLNIHQK------------IHTGERQYECHECGKAFNQKSILIVHQK 515
Query: 623 VGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLL 680
+ TGE Y+C +CG + +F TH + H T C C K F ++ LL
Sbjct: 516 I------HTGEKPYVCTECGRAFIRKSNFITHQRIH--TGEKPYECSDCGKSFTSKSQLL 567
Query: 681 KHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLH 740
H +H Y+C C K F+ +L KH + C+ C + F K + H
Sbjct: 568 VHQPVH--TGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH 625
Query: 741 LAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQC 800
+ H+ EK Y C+ C F ++ LQ+ H + K + C CG++F L
Sbjct: 626 HRI-HTGEKP-YECSDCGKSFTKKSQLQV---HQRIHTGEKPYVCAECGKAFTDRSNLNK 680
Query: 801 HITTHS--KKYNCKFCSKAF 818
H TTH+ K Y C C K F
Sbjct: 681 HQTTHTGDKPYKCGICGKGF 700
Score = 183 bits (464), Expect = 1e-45
Identities = 162/639 (25%), Positives = 248/639 (38%), Gaps = 104/639 (16%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C C K FS S L HE+ H+ + +CT C + F K + H K+HTG++ Y C
Sbjct: 159 YECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICI 218
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHER---------NK 228
EC AF + HL H + HT KPY+C+ C + F+S S L H +VH R K
Sbjct: 219 ECGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGK 278
Query: 229 DGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVY 285
S + + + K++ +K C++C + F + +L H H P E C
Sbjct: 279 VFSNNSNLVTHKKVQSREKSSICTECGKAFTYRSELIIH-QRIHTGEKPYE------CSD 331
Query: 286 CHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNS 343
C + F ++++L H +++H+GEK C C +F L +H H ++P C H
Sbjct: 332 CGKAFTQKSALTVH-QRIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCG- 389
Query: 344 PSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKV 403
T S L V P + G K ++ +T + +
Sbjct: 390 -----------KLFTSKSQLHVHKRIHTGEKPYMCNKCG-KAFTNRSNLITHQKTHTGEK 437
Query: 404 TYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQ 463
+Y C C K F+ + L H + +KP + C C + +LN H K +H +
Sbjct: 438 SYICSKCGK-AFTQRSDLITHQRIHTGEKPYE---CNTCGKAFTQKSHLNIHQK-IHTGE 492
Query: 464 DPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFL 523
Y+C+ C + N + L H + G + C C F+
Sbjct: 493 RQ-----------YECHECGKAFNQKSILIVHQKIHTG--------EKPYVCTECGRAFI 533
Query: 524 TDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKE 583
S+ H R + T ++P Y CS C S F S +L H
Sbjct: 534 RKSNFITHQR---------------IHTGEKP----YECSDCGKS--FTSKSQLLVH--- 569
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGA 641
+H G+K + +++L Q TGE YIC++CG
Sbjct: 570 ---------QPVHTGEKPYVCAECGKAFSGRSNLSKHQKT------HTGEKPYICSECGK 614
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDK 701
+ TH + H T C C K F + L H IH Y+C C K
Sbjct: 615 TFRQKSELITHHRIH--TGEKPYECSDCGKSFTKKSQLQVHQRIH--TGEKPYVCAECGK 670
Query: 702 QFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLH 740
FT +L KH ++C +C + F K +H
Sbjct: 671 AFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVH 709
Score = 169 bits (428), Expect = 2e-41
Identities = 184/747 (24%), Positives = 284/747 (38%), Gaps = 120/747 (16%)
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKM-MQAVGGAPARPTGEYICNQCGAK 642
++K + ++ G+K+ + + +++ LK+ ++ + G Y+C +CG
Sbjct: 57 SYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKL-----YVCIECGKA 111
Query: 643 YTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQ 702
+ F H KTH+ C +C K F SL +H IH Y C C K
Sbjct: 112 FVQKPEFIIHQKTHMRE--KPFKCNECGKSFFQVSSLFRHQRIH--TGEKLYECSQCGKG 167
Query: 703 FTSVDDLQKHLLDMHTFV-FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDF 761
F+ DL H +HT CT C + F K ++++H + H+ E+ Y C C F
Sbjct: 168 FSYNSDLSIH-EKIHTGERHHECTDCGKAFTQKSTLKMHQKI-HTGERS-YICIECGQAF 224
Query: 762 RNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFH 819
+T L + H + K ++C CG+SF ++ +LQ H H+ K Y C K F
Sbjct: 225 IQKTHL---IAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFS 281
Query: 820 AIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDV 879
L H K K+ C G + + E + + +
Sbjct: 282 NNSNLVTH---KKVQSREKSSICTECGKAFTYRSELI------------------IHQRI 320
Query: 880 DTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIV--------KKKAELI----- 926
T E Y C CG A+T ++ L HQ I GE + + +KA LI
Sbjct: 321 HTGEKPYECSDCGKAFTQKSALTVHQ----RIHTGEKSYICMKCGLAFIQKAHLIAHQII 376
Query: 927 ---KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSK 983
+ +KC C + F S++ L H + H G K YMC CG+ F + L H+ TH+
Sbjct: 377 HTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGE-KPYMCNKCGKAFTNRSNLITHQKTHTG 435
Query: 984 SLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM 1043
+ C C + + H ++H + + C C + T L IH H
Sbjct: 436 E-KSYICSKCGKAFTQRSDLITHQRIHTGEK----PYECNTCGKAFTQKSHLNIHQKIH- 489
Query: 1044 QKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLS 1100
TG Q Y+C C K F K L+ K+ PY +C C
Sbjct: 490 -----------TGERQ-----YECHECGKAFNQKSILIVHQKIHTGEKPY-VCTECGRAF 532
Query: 1101 KSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTI 1160
S I + G CS C F S+S+L H Q +
Sbjct: 533 IRKSNFIT-------------------HQRIHTGEKPYECSDCGKSFTSKSQLLVH-QPV 572
Query: 1161 HRELVPDSNSTQLKTPQVSPMPRISPSQSDE--KKTYQCIKCQMVFYNEWDIQVHVANHM 1218
H P + K S +S Q +K Y C +C F + ++ H H
Sbjct: 573 HTGEKPYVCAECGKA--FSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH---HR 627
Query: 1219 IDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFS 1277
I G +EC C ++F ++LQ H H+ E + C C F + L +H +
Sbjct: 628 IHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGE---KPYVCAECGKAFTDRSNLNKHQTT 684
Query: 1278 AHGQEDKIYDCTQCPQKFFFQTELQNH 1304
G DK Y C C + F ++ H
Sbjct: 685 HTG--DKPYKCGICGKGFVQKSVFSVH 709
Score = 161 bits (408), Expect = 3e-39
Identities = 173/716 (24%), Positives = 276/716 (38%), Gaps = 148/716 (20%)
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C K +F+ + L++HLK + E+ ++C C + H K H +
Sbjct: 75 YECAKFEK-IFTQKSQLKVHLKVL---AGEKLYVCIECGKAFVQKPEFIIHQK-THMREK 129
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLT 524
P ++CN C + +++L H R G + C C GF
Sbjct: 130 P-----------FKCNECGKSFFQVSSLFRHQRIHTG--------EKLYECSQCGKGFSY 170
Query: 525 DSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKEN 584
+S L H ++H +G R + C+ C + S LK+++ I
Sbjct: 171 NSDLSIH-EKIH---TGERH---------------HECTDCGKAFTQKSTLKMHQKI--- 208
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAK 642
H G++S I++T L + + TGE Y C+ CG
Sbjct: 209 -----------HTGERSYICIECGQAFIQKTHLIAHRRIH------TGEKPYECSNCGKS 251
Query: 643 YTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQ 702
+ S Q H + H T + C + K F N +L+ H + S+ IC C K
Sbjct: 252 FISKSQLQVHQRVH--TRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSS--ICTECGKA 307
Query: 703 FTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFR 762
FT +L H + C+ C + F K ++ +H + H+ EK Y C C F
Sbjct: 308 FTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRI-HTGEKS-YICMKCGLAFI 365
Query: 763 NETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF-- 818
+ L + H + K HKC CG+ F ++ +L H I T K Y C C KAF
Sbjct: 366 QKAHL---IAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTN 422
Query: 819 --HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQE--------- 867
+ I + H EK + C G + + + + Q + T +
Sbjct: 423 RSNLITHQKTHTGEKSYI-------CSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKA 475
Query: 868 -SHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKK---KA 923
+ SH + + T E Y C CG A+ +++L HQ I GE V +A
Sbjct: 476 FTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQ----KIHTGEKPYVCTECGRA 531
Query: 924 ELIKGN-------------YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPS 970
+ K N Y+C+ C ++F S++ L H H G K Y+C CG+ F
Sbjct: 532 FIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGE-KPYVCAECGKAFSG 590
Query: 971 LLTLTEHKVTHSKSLDTGN----CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCM 1026
L++H+ TH TG C C + + E + H ++H + + C C
Sbjct: 591 RSNLSKHQKTH-----TGEKPYICSECGKTFRQKSELITHHRIHTGEKP----YECSDCG 641
Query: 1027 QTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK 1082
++ T +L++H H TG +K Y CA C K F + +L K
Sbjct: 642 KSFTKKSQLQVHQRIH------------TG-----EKPYVCAECGKAFTDRSNLNK 680
Score = 160 bits (404), Expect = 1e-38
Identities = 194/842 (23%), Positives = 301/842 (35%), Gaps = 199/842 (23%)
Query: 170 GDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKD 229
G+K + ++C S K + K Y+CA + F S L H++V K
Sbjct: 43 GEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEK- 101
Query: 230 GSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHEL 289
C +C + F +QK H + E +C C +
Sbjct: 102 ---------------LYVCIECGKAF-----VQKPEFIIHQKTHMREK--PFKCNECGKS 139
Query: 290 FVEETSLMNHMEQVHSGEKKNSCSICSESFH-----TVEELYSHMDSHQQPESCNHSNSP 344
F + +SL H +++H+GEK CS C + F ++ E + H + C
Sbjct: 140 FFQVSSLFRH-QRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCG----- 193
Query: 345 SLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVT 404
+ T S L + I G+ Q+T + +
Sbjct: 194 ----------KAFTQKSTLKMHQKIHTGERSYICIECGQA-FIQKTHLIAHRRIHTGEKP 242
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C C K F S + LQ+H + KP +IC +V + NL H K+V +
Sbjct: 243 YECSNCGKS-FISKSQLQVHQRVHTRVKP---YICTEYGKVFSNNSNLVTH-KKVQSREK 297
Query: 465 PGLIVSAMPAIVY-----------------QCNFCSEVVNDLNTLQEHIRCSHGFANPAA 507
+ A Y +C+ C + + L H R G
Sbjct: 298 SSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTG------ 351
Query: 508 KDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTN 567
++ C C + F+ + L H ++ T ++P + C +C
Sbjct: 352 --EKSYICMKCGLAFIQKAHLIAH---------------QIIHTGEKP----HKCGHC-- 388
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+F S +L+ H + IH G+K
Sbjct: 389 GKLFTSKSQLHVHKR------------IHTGEKP-------------------------- 410
Query: 628 ARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
Y+CN+CG +T+ + TH KTH T C +C K F + L+ H IH
Sbjct: 411 ------YMCNKCGKAFTNRSNLITHQKTH--TGEKSYICSKCGKAFTQRSDLITHQRIH- 461
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-----FRCTLCQEVFDSKVSIQLHLA 742
Y C +C K FT QK L++H + + C C + F+ K + +H
Sbjct: 462 -TGEKPYECNTCGKAFT-----QKSHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQK 515
Query: 743 VKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHI 802
+ H+ EK Y CT C F +++ + H + K ++C CG+SF ++ +L H
Sbjct: 516 I-HTGEKP-YVCTECGRAFIRKSNF---ITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQ 570
Query: 803 TTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQT 860
H+ K Y C C KAF L KH + CG QK E
Sbjct: 571 PVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFR----QKSE----- 621
Query: 861 LLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVK 920
L+T+ H H G E Y C CG ++T ++ LQ HQ I GE
Sbjct: 622 LITH----HRIHTG--------EKPYECSDCGKSFTKKSQLQVHQ----RIHTGEKP--- 662
Query: 921 KKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVT 980
Y C C + F + L +H TH G K Y C ICG+ F + H+ +
Sbjct: 663 ---------YVCAECGKAFTDRSNLNKHQTTHTGD-KPYKCGICGKGFVQKSVFSVHQSS 712
Query: 981 HS 982
H+
Sbjct: 713 HA 714
Score = 141 bits (356), Expect = 4e-33
Identities = 99/370 (26%), Positives = 158/370 (42%), Gaps = 55/370 (14%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
P+ C C K F+ S L H++ H+ + P+ C C + F ++ + H K HTG+K Y C
Sbjct: 382 PHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYIC 441
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
S+C AF++ L H + HT KPY+C C + F S L+ H ++H +G R
Sbjct: 442 SKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQKIH--------TGER 493
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+C +C + F+ QK I H + E C C F+ +++
Sbjct: 494 Q--------YECHECGKAFN-----QKSILIVHQKIHTGE--KPYVCTECGRAFIRKSNF 538
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSV 354
+ H +++H+GEK CS C +SF + +L H H ++P C
Sbjct: 539 ITH-QRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECG------------ 585
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
+ + SNLS T P I G K Q++ +T + Y C C K
Sbjct: 586 KAFSGRSNLSKHQKTHTGEKPYICSECG-KTFRQKSELITHHRIHTGEKPYECSDCGKS- 643
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
F+ + LQ+H + +KP ++C C + NLN+H + H P
Sbjct: 644 FTKKSQLQVHQRIHTGEKP---YVCAECGKAFTDRSNLNKH-QTTHTGDKP--------- 690
Query: 475 IVYQCNFCSE 484
Y+C C +
Sbjct: 691 --YKCGICGK 698
Score = 134 bits (337), Expect = 6e-31
Identities = 133/574 (23%), Positives = 219/574 (38%), Gaps = 106/574 (18%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C KSF S L+ H++ H+ P+ CT ++F + + H K+ + +K C
Sbjct: 242 PYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSIC 301
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+EC AF+ L IH + HT KPY+C+ C + F S+L H ++H K
Sbjct: 302 TECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEK-------- 353
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+ C +C F +QK H E +C +C +LF ++ L
Sbjct: 354 --------SYICMKCGLAF-----IQKAHLIAHQIIHTGE--KPHKCGHCGKLFTSKSQL 398
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPES--CNHSNSPSLVTVGYTSV 354
H +++H+GEK C+ C ++F L +H +H +S C+
Sbjct: 399 HVH-KRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCG------------ 445
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
+ T S+L + + P + K Q++ + Y C C K
Sbjct: 446 KAFTQRSDL-ITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQKIHTGERQYECHECGK-A 503
Query: 415 FSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPA 474
F+ ++L +H K +KP ++C C N H +++H + P
Sbjct: 504 FNQKSILIVHQKIHTGEKP---YVCTECGRAFIRKSNFITH-QRIHTGEKP--------- 550
Query: 475 IVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQ 534
Y+C+ C + + L H P + C C F S+L +H ++
Sbjct: 551 --YECSDCGKSFTSKSQLLVH--------QPVHTGEKPYVCAECGKAFSGRSNLSKH-QK 599
Query: 535 VHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNY 594
H T ++P Y CS C + F +L H +
Sbjct: 600 TH--------------TGEKP----YICSECGKT--FRQKSELITH------------HR 627
Query: 595 IHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTH 652
IH G+K S +++ L++ Q + TGE Y+C +CG +T + H
Sbjct: 628 IHTGEKPYECSDCGKSFTKKSQLQVHQRI------HTGEKPYVCAECGKAFTDRSNLNKH 681
Query: 653 LKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIH 686
TH T C C K F + H + H
Sbjct: 682 QTTH--TGDKPYKCGICGKGFVQKSVFSVHQSSH 713
Score = 124 bits (310), Expect = 8e-28
Identities = 83/301 (27%), Positives = 125/301 (41%), Gaps = 35/301 (11%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C C + F SD+ H+ ++ G + TC + S + H
Sbjct: 436 EKSYICSKCGKAFTQRSDLITHQ----RIHTGEKPYECNTCGKAFTQKSHLNIHQKIHT- 490
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE + Y C C K+F++ S L H++ H+ + P+ CT C R F K +
Sbjct: 491 ----GERQ------YECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFIT 540
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H ++HTG+K Y CS+C +F+ L +H HT KPY CA C + F S+L H +
Sbjct: 541 HQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKT 600
Query: 224 H---------ERNKDGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPE 271
H E K Q + ++ +K CS C + F LQ H H
Sbjct: 601 HTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVH-QRIHTG 659
Query: 272 CSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDS 331
P C C + F + ++L H + H+G+K C IC + F H S
Sbjct: 660 EKP------YVCAECGKAFTDRSNLNKH-QTTHTGDKPYKCGICGKGFVQKSVFSVHQSS 712
Query: 332 H 332
H
Sbjct: 713 H 713
>gi|25014093 zinc finger protein 585B [Homo sapiens]
Length = 769
Score = 198 bits (504), Expect = 2e-50
Identities = 171/709 (24%), Positives = 272/709 (38%), Gaps = 145/709 (20%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
P C C KSF ++S L H + H+ + ++C+ C + F + H K+HTG++ + C
Sbjct: 185 PPKCNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKIHTGERHHEC 244
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
++C AF++ LKIH K HT + Y C C + F+ + L H ++H K
Sbjct: 245 TDCGKAFTQKSTLKIHQKIHTGERSYICIECGQAFIQKTQLIAHRRIHSGEK-------- 296
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+C+ C + F LQ H H P C ++F ++L
Sbjct: 297 --------PYECNNCGKSFISKSQLQVH-QRVHTRVKP------YICTEYGKVFSNNSNL 341
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSV 354
+ H E++ S EK + C+ C ++F EL H H ++P C+ +T
Sbjct: 342 ITH-EKIQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGR------AFTQK 394
Query: 355 SSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQL 414
S+ T + TG S Y C+ C
Sbjct: 395 SALTVHQRIH-----------------------------TGEKS------YICMKCGLAF 419
Query: 415 FSSLAVLQIHLKTMH-LDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMP 473
+ + HL T + E+ + C +C ++ S L+ H K++H + P
Sbjct: 420 -----IRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVH-KRIHTGEKP-------- 465
Query: 474 AIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIR 533
Y CN C + + + L H + G ++ C C F S L H R
Sbjct: 466 ---YVCNKCGKAFTNRSNLITHQKTHTG--------EKSYICSKCGKAFTQRSDLITHQR 514
Query: 534 QVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALN 593
+ T ++P Y C+ C + F LN H K
Sbjct: 515 ---------------IHTGEKP----YECNTCGKA--FTQKSNLNIHQK----------- 542
Query: 594 YIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQT 651
IH G++ +++ L + Q + TGE Y+C +CG + +F T
Sbjct: 543 -IHTGERQYECHECGKAFNQKSILIVHQKI------HTGEKPYVCTECGRAFIRKSNFIT 595
Query: 652 HLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQK 711
H + H T C C K F ++ LL H +H Y+C C K F+ +L K
Sbjct: 596 HQRIH--TGEKPYECSDCGKSFTSKSQLLVHQPVH--TGEKPYVCAECGKAFSGRSNLSK 651
Query: 712 HLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHV 771
H + C+ C + F K + H + H+ EK Y C+ C F ++ LQ+
Sbjct: 652 HQKTHTGEKPYICSECGKTFRQKSELITHHRI-HTGEKP-YECSDCGKSFTKKSQLQV-- 707
Query: 772 KHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAF 818
H + K + C CG++F L H TTH+ K Y C C K F
Sbjct: 708 -HQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTHTGDKPYKCGICGKGF 755
Score = 193 bits (490), Expect = 1e-48
Identities = 197/836 (23%), Positives = 312/836 (37%), Gaps = 181/836 (21%)
Query: 153 RLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFL 212
++ +K + + K+++G+K Y C+E +F+ K+HLK T K Y C C R F+
Sbjct: 109 KIIGYKPASSQDQKIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLYVCIECGRAFV 168
Query: 213 SSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPEC 272
H + H R K KC++C + F L +H
Sbjct: 169 QKPEFITHQKTHMREKP----------------PKCNECGKSFFQVSSLFRHHRI----- 207
Query: 273 SPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH 332
+ +C C + F + L H E++H+GE+ + C+ C ++F L H H
Sbjct: 208 --HTGEKLYECSECGKGFPYNSDLSIH-EKIHTGERHHECTDCGKAFTQKSTLKIHQKIH 264
Query: 333 QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKS---RGRKRAAQQ 389
S + G + T ++ + S KS + + + Q+
Sbjct: 265 ------TGERSYICIECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQVHQR 318
Query: 390 TPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSL 449
P Y C K +FS+ + L H K + E++ IC C +
Sbjct: 319 VHTRVKP--------YICTEYGK-VFSNNSNLITHEK---IQSREKSSICTECGKAFTYR 366
Query: 450 YNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKD 509
L H +++H + P Y+C+ C + L H R G
Sbjct: 367 SELIIH-QRIHTGEKP-----------YECSDCGRAFTQKSALTVHQRIHTG-------- 406
Query: 510 SNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSP 569
++ C C + F+ + L H ++ T ++P Y C +C
Sbjct: 407 EKSYICMKCGLAFIRKAHLITH---------------QIIHTGEKP----YKCGHC--GK 445
Query: 570 IFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPAR 629
+F S +L+ H + IH G+K
Sbjct: 446 LFTSKSQLHVHKR------------IHTGEKP---------------------------- 465
Query: 630 PTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMI 689
Y+CN+CG +T+ + TH KTH T C +C K F + L+ H IH
Sbjct: 466 ----YVCNKCGKAFTNRSNLITHQKTH--TGEKSYICSKCGKAFTQRSDLITHQRIH--T 517
Query: 690 TSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNE 748
Y C +C K FT +L H +HT + C C + F+ K + +H + H+ E
Sbjct: 518 GEKPYECNTCGKAFTQKSNLNIHQ-KIHTGERQYECHECGKAFNQKSILIVHQKI-HTGE 575
Query: 749 KKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS-- 806
K Y CT C F +++ + H + K ++C CG+SF ++ +L H H+
Sbjct: 576 KP-YVCTECGRAFIRKSNF---ITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGE 631
Query: 807 KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQ 866
K Y C C KAF L KH + CG QK E L+T+
Sbjct: 632 KPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFR----QKSE-----LITH-- 680
Query: 867 ESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELI 926
H H G E Y C CG ++T ++ LQ HQ I GE
Sbjct: 681 --HRIHTG--------EKPYECSDCGKSFTKKSQLQVHQ----RIHTGEKP--------- 717
Query: 927 KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHS 982
Y C C + F + + L +H TH G K Y C ICG+ F + H+ +H+
Sbjct: 718 ---YVCAECGKAFSNRSNLNKHQTTHTGD-KPYKCGICGKGFVQKSVFSVHQSSHA 769
Score = 175 bits (443), Expect = 3e-43
Identities = 159/639 (24%), Positives = 245/639 (38%), Gaps = 104/639 (16%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C C K F S L HE+ H+ + +CT C + F K + H K+HTG++ Y C
Sbjct: 214 YECSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERSYICI 273
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHER---------NK 228
EC AF + L H + H+ KPY+C C + F+S S L H +VH R K
Sbjct: 274 ECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHTRVKPYICTEYGK 333
Query: 229 DGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVY 285
S + + + K++ +K C++C + F + +L H H P E C
Sbjct: 334 VFSNNSNLITHEKIQSREKSSICTECGKAFTYRSELIIH-QRIHTGEKPYE------CSD 386
Query: 286 CHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNS 343
C F ++++L H +++H+GEK C C +F L +H H ++P C H
Sbjct: 387 CGRAFTQKSALTVH-QRIHTGEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCG- 444
Query: 344 PSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKV 403
T S L V P + G K ++ +T + +
Sbjct: 445 -----------KLFTSKSQLHVHKRIHTGEKPYVCNKCG-KAFTNRSNLITHQKTHTGEK 492
Query: 404 TYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQ 463
+Y C C K F+ + L H + +KP + C C + NLN H K +H +
Sbjct: 493 SYICSKCGK-AFTQRSDLITHQRIHTGEKPYE---CNTCGKAFTQKSNLNIHQK-IHTGE 547
Query: 464 DPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFL 523
Y+C+ C + N + L H + G + C C F+
Sbjct: 548 RQ-----------YECHECGKAFNQKSILIVHQKIHTG--------EKPYVCTECGRAFI 588
Query: 524 TDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKE 583
S+ H R + T ++P Y CS C S F S +L H
Sbjct: 589 RKSNFITHQR---------------IHTGEKP----YECSDCGKS--FTSKSQLLVH--- 624
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGA 641
+H G+K + +++L Q TGE YIC++CG
Sbjct: 625 ---------QPVHTGEKPYVCAECGKAFSGRSNLSKHQKT------HTGEKPYICSECGK 669
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDK 701
+ TH + H T C C K F + L H IH Y+C C K
Sbjct: 670 TFRQKSELITHHRIH--TGEKPYECSDCGKSFTKKSQLQVHQRIH--TGEKPYVCAECGK 725
Query: 702 QFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLH 740
F++ +L KH ++C +C + F K +H
Sbjct: 726 AFSNRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVH 764
Score = 174 bits (442), Expect = 4e-43
Identities = 178/702 (25%), Positives = 262/702 (37%), Gaps = 138/702 (19%)
Query: 630 PTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
PTGE Y+C +CG + F TH KTH+ PK C +C K F SL +H IH
Sbjct: 152 PTGEKLYVCIECGRAFVQKPEFITHQKTHMREKPPK--CNECGKSFFQVSSLFRHHRIH- 208
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFV-FFRCTLCQEVFDSKVSIQLHLAVKHS 746
Y C C K F DL H +HT CT C + F K ++++H + H+
Sbjct: 209 -TGEKLYECSECGKGFPYNSDLSIHE-KIHTGERHHECTDCGKAFTQKSTLKIHQKI-HT 265
Query: 747 NEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS 806
E+ Y C C F +T L + H + + K ++C CG+SF ++ +LQ H H+
Sbjct: 266 GERS-YICIECGQAFIQKTQL---IAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHT 321
Query: 807 --KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTN 864
K Y C K F L H E++Q E
Sbjct: 322 RVKPYICTEYGKVFSNNSNLITH---------------------EKIQSREKSSICTECG 360
Query: 865 SQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVK---- 920
++ S + + T E Y C CG A+T ++ L HQ I GE + +
Sbjct: 361 KAFTYRSELIIHQRIHTGEKPYECSDCGRAFTQKSALTVHQ----RIHTGEKSYICMKCG 416
Query: 921 ----KKAELIKGN--------YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERF 968
+KA LI YKC C + F S++ L H + H G K Y+C CG+ F
Sbjct: 417 LAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGE-KPYVCNKCGKAF 475
Query: 969 PSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQT 1028
+ L H+ TH+ + C C + + H ++H + + C C +
Sbjct: 476 TNRSNLITHQKTHTGE-KSYICSKCGKAFTQRSDLITHQRIHTGEKP----YECNTCGKA 530
Query: 1029 VTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDI 1085
T L IH H TG Q Y+C C K F K L+ K+
Sbjct: 531 FTQKSNLNIHQKIH------------TGERQ-----YECHECGKAFNQKSILIVHQKIHT 573
Query: 1086 NGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNV 1145
PY +C C S I + G CS C
Sbjct: 574 GEKPY-VCTECGRAFIRKSNFIT-------------------HQRIHTGEKPYECSDCGK 613
Query: 1146 KFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFY 1205
F S+S+L H Q +H +K Y C +C F
Sbjct: 614 SFTSKSQLLVH-QPVHTG----------------------------EKPYVCAECGKAFS 644
Query: 1206 NEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVF 1265
++ H H ++ + C C +TF ++L H H+ E ++C C F
Sbjct: 645 GRSNLSKHQKTHTGEKP--YICSECGKTFRQKSELITHHRIHTGEK---PYECSDCGKSF 699
Query: 1266 VQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMT 1307
+ ++LQ H G+ K Y C +C + F ++ L H T
Sbjct: 700 TKKSQLQVHQRIHTGE--KPYVCAECGKAFSNRSNLNKHQTT 739
Score = 160 bits (404), Expect = 1e-38
Identities = 172/702 (24%), Positives = 265/702 (37%), Gaps = 98/702 (13%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y C + G +T F+ HLK L C +C + F + + H H
Sbjct: 130 YECAEFGKSFTWKSQFKVHLKVPTGEKL--YVCIECGRAFVQKPEFITHQKTHMREKPPK 187
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
C C K F V L +H + C+ C + F + +H + H+ E+ +
Sbjct: 188 --CNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKI-HTGERH-HE 243
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNC 811
CT C F ++ L++H K + + + CI CG++F + +L H HS K Y C
Sbjct: 244 CTDCGKAFTQKSTLKIHQK---IHTGERSYICIECGQAFIQKTQLIAHRRIHSGEKPYEC 300
Query: 812 KFCSKAFHAIILLEKHLREKHCV---FETKTPNCGTNGAS----EQVQKEEVELQTLLTN 864
C K+F + L+ H R V T+ +N ++ E++Q E
Sbjct: 301 NNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLITHEKIQSREKSSICTECG 360
Query: 865 SQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIV----- 919
++ S + + T E Y C CG A+T ++ L HQ I GE + +
Sbjct: 361 KAFTYRSELIIHQRIHTGEKPYECSDCGRAFTQKSALTVHQ----RIHTGEKSYICMKCG 416
Query: 920 ---KKKAELI--------KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERF 968
+KA LI + YKC C + F S++ L H + H G K Y+C CG+ F
Sbjct: 417 LAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGE-KPYVCNKCGKAF 475
Query: 969 PSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQT 1028
+ L H+ TH+ + C C + + H ++H + + C C +
Sbjct: 476 TNRSNLITHQKTHTGE-KSYICSKCGKAFTQRSDLITHQRIHTGEK----PYECNTCGKA 530
Query: 1029 VTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDI 1085
T L IH H TG Q Y+C C K F K L+ K+
Sbjct: 531 FTQKSNLNIHQKIH------------TGERQ-----YECHECGKAFNQKSILIVHQKIHT 573
Query: 1086 NGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNV 1145
PY +C C S I + G CS C
Sbjct: 574 GEKPY-VCTECGRAFIRKSNFIT-------------------HQRIHTGEKPYECSDCGK 613
Query: 1146 KFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDE--KKTYQCIKCQMV 1203
F S+S+L H Q +H P + K S +S Q +K Y C +C
Sbjct: 614 SFTSKSQLLVH-QPVHTGEKPYVCAECGKA--FSGRSNLSKHQKTHTGEKPYICSECGKT 670
Query: 1204 FYNEWDIQVHVANHMIDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCF 1262
F + ++ H H I G +EC C ++F ++LQ H H+ E + C C
Sbjct: 671 FRQKSELITH---HRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGE---KPYVCAECG 724
Query: 1263 TVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
F + L +H + G DK Y C C + F ++ H
Sbjct: 725 KAFSNRSNLNKHQTTHTG--DKPYKCGICGKGFVQKSVFSVH 764
Score = 152 bits (383), Expect = 3e-36
Identities = 168/715 (23%), Positives = 269/715 (37%), Gaps = 144/715 (20%)
Query: 404 TYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQ 463
+Y C K F+ + ++HLK + E+ ++C C H K +
Sbjct: 129 SYECAEFGKS-FTWKSQFKVHLK---VPTGEKLYVCIECGRAFVQKPEFITHQKTHMREK 184
Query: 464 DPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFL 523
P +CN C + +++L H R G + C C GF
Sbjct: 185 PP------------KCNECGKSFFQVSSLFRHHRIHTG--------EKLYECSECGKGFP 224
Query: 524 TDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKE 583
+S L H ++H +G R + C+ C + S LK+++ I
Sbjct: 225 YNSDLSIH-EKIH---TGERH---------------HECTDCGKAFTQKSTLKIHQKI-- 263
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKY 643
H G++S I++T L + + Y CN CG +
Sbjct: 264 ------------HTGERSYICIECGQAFIQKTQLIAHRRIHSGEK----PYECNNCGKSF 307
Query: 644 TSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQF 703
S Q H + H T + C + K F N +L+ H I S+ IC C K F
Sbjct: 308 ISKSQLQVHQRVH--TRVKPYICTEYGKVFSNNSNLITHEKIQSREKSS--ICTECGKAF 363
Query: 704 TSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRN 763
T +L H + C+ C F K ++ +H + H+ EK Y C C F
Sbjct: 364 TYRSELIIHQRIHTGEKPYECSDCGRAFTQKSALTVHQRI-HTGEKS-YICMKCGLAFIR 421
Query: 764 ETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF--- 818
+ L + H + K +KC CG+ F ++ +L H I T K Y C C KAF
Sbjct: 422 KAHL---ITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNR 478
Query: 819 -HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQE---------- 867
+ I + H EK + C G + + + + Q + T +
Sbjct: 479 SNLITHQKTHTGEKSYI-------CSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAF 531
Query: 868 SHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKK---KAE 924
+ S+ + + T E Y C CG A+ +++L HQ I GE V +A
Sbjct: 532 TQKSNLNIHQKIHTGERQYECHECGKAFNQKSILIVHQ----KIHTGEKPYVCTECGRAF 587
Query: 925 LIKGN-------------YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSL 971
+ K N Y+C+ C ++F S++ L H H G K Y+C CG+ F
Sbjct: 588 IRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGE-KPYVCAECGKAFSGR 646
Query: 972 LTLTEHKVTHSKSLDTGN----CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQ 1027
L++H+ TH TG C C + + E + H ++H + + C C +
Sbjct: 647 SNLSKHQKTH-----TGEKPYICSECGKTFRQKSELITHHRIHTGEKP----YECSDCGK 697
Query: 1028 TVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK 1082
+ T +L++H H TG +K Y CA C K F ++ +L K
Sbjct: 698 SFTKKSQLQVHQRIH------------TG-----EKPYVCAECGKAFSNRSNLNK 735
Score = 138 bits (347), Expect = 4e-32
Identities = 171/747 (22%), Positives = 277/747 (37%), Gaps = 127/747 (17%)
Query: 282 QCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCN 339
+C + F ++ H++ V +GEK C C +F E +H +H ++P CN
Sbjct: 131 ECAEFGKSFTWKSQFKVHLK-VPTGEKLYVCIECGRAFVQKPEFITHQKTHMREKPPKCN 189
Query: 340 HSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSK 399
+ VSS + + E S K +
Sbjct: 190 ECGK------SFFQVSSLFRHHRIHTGEK-LYEC------SECGKGFPYNSDLSIHEKIH 236
Query: 400 QAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQV 459
+ + C C K F+ + L+IH K + E+++IC C + L H +++
Sbjct: 237 TGERHHECTDCGKA-FTQKSTLKIHQK---IHTGERSYICIECGQAFIQKTQLIAH-RRI 291
Query: 460 HEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCY 519
H + P Y+CN C + + LQ H R H P + C
Sbjct: 292 HSGEKP-----------YECNNCGKSFISKSQLQVHQRV-HTRVKP-------YICTEYG 332
Query: 520 MGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNK 579
F +S+L H + SR S + C+ C + + S L +++
Sbjct: 333 KVFSNNSNLITH------EKIQSREKSSI-------------CTECGKAFTYRSELIIHQ 373
Query: 580 HIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICN 637
I H G+K S ++++L + Q + TGE YIC
Sbjct: 374 RI--------------HTGEKPYECSDCGRAFTQKSALTVHQRIH------TGEKSYICM 413
Query: 638 QCGAKYTSLDSFQTHLKTH--LDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYI 695
+CG + + HL TH + T C C K F ++ L H IH Y+
Sbjct: 414 KCGLAFIR----KAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIH--TGEKPYV 467
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCT 755
C C K FT+ +L H + C+ C + F + + H + H+ EK Y C
Sbjct: 468 CNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRI-HTGEKP-YECN 525
Query: 756 SCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKF 813
+C F +++L +H K + E Q ++C CG++F + L H I T K Y C
Sbjct: 526 TCGKAFTQKSNLNIHQKIHTGERQ---YECHECGKAFNQKSILIVHQKIHTGEKPYVCTE 582
Query: 814 CSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQE------ 867
C +AF I + + K C G S + + + Q + T +
Sbjct: 583 CGRAF---IRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAEC 639
Query: 868 ----SHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKA 923
S S+ + T E Y C CG + ++ L H H I GE
Sbjct: 640 GKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH----HRIHTGEKP------ 689
Query: 924 ELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSK 983
Y+C+ C ++F ++ L+ H + H G K Y+C CG+ F + L +H+ TH+
Sbjct: 690 ------YECSDCGKSFTKKSQLQVHQRIHTGE-KPYVCAECGKAFSNRSNLNKHQTTHTG 742
Query: 984 SLDTGNCRICKMPLQSEEEFLEHCQMH 1010
C IC + F H H
Sbjct: 743 D-KPYKCGICGKGFVQKSVFSVHQSSH 768
Score = 123 bits (308), Expect = 1e-27
Identities = 83/301 (27%), Positives = 125/301 (41%), Gaps = 35/301 (11%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C C + F SD+ H+ ++ G + TC + S+ + H
Sbjct: 491 EKSYICSKCGKAFTQRSDLITHQ----RIHTGEKPYECNTCGKAFTQKSNLNIHQKIHT- 545
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE + Y C C K+F++ S L H++ H+ + P+ CT C R F K +
Sbjct: 546 ----GERQ------YECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFIT 595
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H ++HTG+K Y CS+C +F+ L +H HT KPY CA C + F S+L H +
Sbjct: 596 HQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKT 655
Query: 224 H---------ERNKDGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPE 271
H E K Q + ++ +K CS C + F LQ H H
Sbjct: 656 HTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVH-QRIHTG 714
Query: 272 CSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDS 331
P C C + F ++L H + H+G+K C IC + F H S
Sbjct: 715 EKP------YVCAECGKAFSNRSNLNKH-QTTHTGDKPYKCGICGKGFVQKSVFSVHQSS 767
Query: 332 H 332
H
Sbjct: 768 H 768
Score = 112 bits (279), Expect = 3e-24
Identities = 137/591 (23%), Positives = 216/591 (36%), Gaps = 128/591 (21%)
Query: 749 KKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTH--S 806
+K Y C F ++ ++H+K + K++ CI CG +F + E H TH
Sbjct: 127 EKSYECAEFGKSFTWKSQFKVHLK---VPTGEKLYVCIECGRAFVQKPEFITHQKTHMRE 183
Query: 807 KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQ 866
K C C K+F + L +H R + CG
Sbjct: 184 KPPKCNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKG--------------------- 222
Query: 867 ESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIV------- 919
+NS E + T E + C CG A+T ++ L+ HQ I GE + +
Sbjct: 223 FPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQ----KIHTGERSYICIECGQA 278
Query: 920 -KKKAELI--------KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPS 970
+K +LI + Y+CN C ++F S++ L+ H + H VK Y+C G+ F +
Sbjct: 279 FIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHT-RVKPYICTEYGKVFSN 337
Query: 971 LLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVT 1030
L H+ S+ + C C E + H ++H + + C C + T
Sbjct: 338 NSNLITHEKIQSRE-KSSICTECGKAFTYRSELIIHQRIHTGEK----PYECSDCGRAFT 392
Query: 1031 STLELKIHGTFHMQKTGNGSAV-QTTG----RGQHV---------QKLYKCASCLKEFRS 1076
L +H H TG S + G R H+ +K YKC C K F S
Sbjct: 393 QKSALTVHQRIH---TGEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTS 449
Query: 1077 KQDL---VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV 1133
K L ++ PY +C C TNR L ++ K
Sbjct: 450 KSQLHVHKRIHTGEKPY-VCNKCGKAF------------TNRSNLITHQ-------KTHT 489
Query: 1134 GGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKK 1193
G CS C F S+L H Q IH +K
Sbjct: 490 GEKSYICSKCGKAFTQRSDLITH-QRIH----------------------------TGEK 520
Query: 1194 TYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMG 1253
Y+C C F + ++ +H H + +EC C + F+ + L H H+ E
Sbjct: 521 PYECNTCGKAFTQKSNLNIHQKIHTGER--QYECHECGKAFNQKSILIVHQKIHTGE--- 575
Query: 1254 GTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+ C C F++ + H G +K Y+C+ C + F +++L H
Sbjct: 576 KPYVCTECGRAFIRKSNFITHQRIHTG--EKPYECSDCGKSFTSKSQLLVH 624
>gi|68303809 zinc finger protein 43 [Homo sapiens]
Length = 809
Score = 197 bits (501), Expect = 6e-50
Identities = 180/720 (25%), Positives = 279/720 (38%), Gaps = 123/720 (17%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+ C+ C KSF L +L H+ H+ KC C + F +H +++TG+K Y C
Sbjct: 174 FKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCE 233
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
EC F+ S L H K +T K YKC C + F SS L H + K
Sbjct: 234 ECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEK--------- 284
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
KC +C + F+ +L +H + HP P +C C + F ++L
Sbjct: 285 -------FYKCKECAKAFNQSSNLTEH-KKIHPGEKP------YKCEECGKAFNWPSTLT 330
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPE-----SCNHSNSPSLVTVGYT 352
H +++H+GEK +C C ++F+ L +H H + C + S S
Sbjct: 331 KH-KRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRS------- 382
Query: 353 SVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPS-SKQAKVTYSCIYCN 411
SNL+ E P + G +A + + +T + + Y C C
Sbjct: 383 --------SNLTKHKKIHTEKKPYKCEECG--KAFKWSSKLTEHKLTHTGEKPYKCEECG 432
Query: 412 KQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSA 471
K F+ + L H + +KP + C+ C + NL H K++H A+ P
Sbjct: 433 K-AFNWPSTLTKHNRIHTGEKP---YKCEVCGKAFNQFSNLTTH-KRIHTAEKP------ 481
Query: 472 MPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEH 531
Y+C C + + + L +H + + + C C F S L EH
Sbjct: 482 -----YKCEECGKAFSRSSNLTKHKKIH--------IEKKPYKCEECGKAFKWSSKLTEH 528
Query: 532 IRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLA 591
+ T ++P Y C C + FN L KH +
Sbjct: 529 ---------------KITHTGEKP----YKCEECGKA--FNHFSILTKHKR--------- 558
Query: 592 LNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSF 649
IH G+K + ++L + + TGE Y C +CG +T +
Sbjct: 559 ---IHTGEKPYKCEECGKAFTQSSNLTTHKKI------HTGEKFYKCEECGKAFTQSSNL 609
Query: 650 QTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDL 709
TH K H T C +C K F +L KH IH Y CE C K F L
Sbjct: 610 TTHKKIH--TGGKPYKCEECGKAFNQFSTLTKHKIIH--TEEKPYKCEECGKAFKWSSTL 665
Query: 710 QKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQL 769
KH + ++C C + F ++ H + H+ EK Y+C C F ++L
Sbjct: 666 TKHKIIHTGEKPYKCEECGKAFKLSSTLSTHKII-HTGEKP-YKCEKCGKAFNRSSNL-- 721
Query: 770 HVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKK--YNCKFCSKAFHAIILLEKH 827
++H + + +KC CG++F L H H+K+ Y CK C KAF+ L H
Sbjct: 722 -IEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTH 780
Score = 167 bits (424), Expect = 5e-41
Identities = 167/704 (23%), Positives = 251/704 (35%), Gaps = 161/704 (22%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C+ C K F+ S L H+++++ +KC C + F H + TG+K Y C
Sbjct: 229 PYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKC 288
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH--ERNKDGSQSG 234
EC AF++S +L H K H KPYKC C + F S+L H ++H E+ + G
Sbjct: 289 KECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECG 348
Query: 235 SRMEDWKMKDTQ----------KCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
+ T KC++C E F +L KH + H E P +C
Sbjct: 349 KAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKH-KKIHTEKKP------YKCE 401
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN 342
C + F + L H + H+GEK C C ++F+ L H H ++P C
Sbjct: 402 ECGKAFKWSSKLTEH-KLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKC---- 456
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
+ + S+ T + A+
Sbjct: 457 --EVCGKAFNQFSNLTTHKRIHT-----------------------------------AE 479
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K FS + L H K +H++K + + C+ C + L EH K H
Sbjct: 480 KPYKCEECGK-AFSRSSNLTKH-KKIHIEK--KPYKCEECGKAFKWSSKLTEH-KITHTG 534
Query: 463 QDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGF 522
+ P Y+C C + N + L +H R G + C C F
Sbjct: 535 EKP-----------YKCEECGKAFNHFSILTKHKRIHTG--------EKPYKCEECGKAF 575
Query: 523 LTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIK 582
S+L H +++H +G +F Y C C + F L H K
Sbjct: 576 TQSSNLTTH-KKIH---TGEKF---------------YKCEECGKA--FTQSSNLTTHKK 614
Query: 583 ENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAK 642
IH G K Y C +CG
Sbjct: 615 ------------IHTGGK--------------------------------PYKCEECGKA 630
Query: 643 YTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQ 702
+ + H H + K C +C K F +L KH IH Y CE C K
Sbjct: 631 FNQFSTLTKHKIIHTEEKPYK--CEECGKAFKWSSTLTKHKIIH--TGEKPYKCEECGKA 686
Query: 703 FTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFR 762
F L H + ++C C + F+ ++ H + H+ E+ Y+C C F
Sbjct: 687 FKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKI-HTGEQP-YKCEECGKAFN 744
Query: 763 NETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS 806
+ L H K H + Q +KC CG++F L H H+
Sbjct: 745 YSSHLNTH-KRIHTKEQ--PYKCKECGKAFNQYSNLTTHNKIHT 785
Score = 166 bits (421), Expect = 1e-40
Identities = 190/851 (22%), Positives = 291/851 (34%), Gaps = 216/851 (25%)
Query: 169 TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNK 228
T K + +C AF + + H +HT K +KC C + F L H +H R
Sbjct: 141 TQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTR-- 198
Query: 229 DGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHE 288
+ KC +C + F+ P + KH
Sbjct: 199 --------------VNFCKCEKCGKAFNCPSIITKH------------------------ 220
Query: 289 LFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQP-----ESCNHS-N 342
+++++GEK +C C + F+ L +H ++ + E C + N
Sbjct: 221 ------------KRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFN 268
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSS-KQA 401
S++T + ++ K + +A Q+ ++T
Sbjct: 269 KSSILT------------------THKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPG 310
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
+ Y C C K F+ + L H + +KP + C+ C + NL H K++H
Sbjct: 311 EKPYKCEECGKA-FNWPSTLTKHKRIHTGEKP---YTCEECGKAFNQFSNLTTH-KRIHT 365
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
A+ Y+C C E + + L +H + + + C C
Sbjct: 366 AEK-----------FYKCTECGEAFSRSSNLTKHKKIH--------TEKKPYKCEECGKA 406
Query: 522 FLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
F S L EH + T ++P Y C C + FN L KH
Sbjct: 407 FKWSSKLTEH---------------KLTHTGEKP----YKCEECGKA--FNWPSTLTKH- 444
Query: 582 KENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGA 641
N IH G+K Y C CG
Sbjct: 445 -----------NRIHTGEKP--------------------------------YKCEVCGK 461
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDK 701
+ + TH + H T C +C K F +L KH IH I Y CE C K
Sbjct: 462 AFNQFSNLTTHKRIH--TAEKPYKCEECGKAFSRSSNLTKHKKIH--IEKKPYKCEECGK 517
Query: 702 QFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDF 761
F L +H + ++C C + F+ + H + H+ EK Y+C C F
Sbjct: 518 AFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKRI-HTGEKP-YKCEECGKAF 575
Query: 762 RNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFH 819
++L H K + K +KC CG++F L H I T K Y C+ C KAF+
Sbjct: 576 TQSSNLTTHKK---IHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFN 632
Query: 820 AIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDV 879
L KH K E K C G + + + LT + H
Sbjct: 633 QFSTLTKH---KIIHTEEKPYKCEECGKA-------FKWSSTLTKHKIIH---------- 672
Query: 880 DTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTF 939
T E Y C+ CG A+ + + L H++ I GE YKC C + F
Sbjct: 673 -TGEKPYKCEECGKAFKLSSTLSTHKI----IHTGEKP------------YKCEKCGKAF 715
Query: 940 FSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQS 999
+ L EH + H G + Y C CG+ F L HK H+K C+ C
Sbjct: 716 NRSSNLIEHKKIHTGE-QPYKCEECGKAFNYSSHLNTHKRIHTKE-QPYKCKECGKAFNQ 773
Query: 1000 EEEFLEHCQMH 1010
H ++H
Sbjct: 774 YSNLTTHNKIH 784
Score = 163 bits (412), Expect = 1e-39
Identities = 157/674 (23%), Positives = 246/674 (36%), Gaps = 157/674 (23%)
Query: 46 VHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGC 105
++ C+ C + F S +T HKI + G C+ + S+ + H
Sbjct: 257 LYKCEECGKAFNKSSILTTHKI----IRTGEKFYKCKECAKAFNQSSNLTEHKKIHP--- 309
Query: 106 DFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHI 165
GE+ PY C+ C K+F+ S L H++ H+ + P+ C C + F + H
Sbjct: 310 --GEK------PYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHK 361
Query: 166 KLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHE 225
++HT +K Y C+EC AFSRS +L H K HT KPYKC C + F SS L H H
Sbjct: 362 RIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHT 421
Query: 226 RNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVY 285
K KC +C + F++P L KH
Sbjct: 422 GEK----------------PYKCEECGKAFNWPSTLTKH--------------------- 444
Query: 286 CHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNS 343
++H+GEK C +C ++F+ L +H H ++P C
Sbjct: 445 ---------------NRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECG- 488
Query: 344 PSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPS-SKQAK 402
+ + SNL+ +E P + G +A + + +T + +
Sbjct: 489 -----------KAFSRSSNLTKHKKIHIEKKPYKCEECG--KAFKWSSKLTEHKITHTGE 535
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K F+ ++L H K +H E+ + C+ C + NL H K++H
Sbjct: 536 KPYKCEECGK-AFNHFSILTKH-KRIHTG--EKPYKCEECGKAFTQSSNLTTH-KKIHTG 590
Query: 463 QDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGF 522
+ Y+C C + + L H + G + C C F
Sbjct: 591 EK-----------FYKCEECGKAFTQSSNLTTHKKIHTG--------GKPYKCEECGKAF 631
Query: 523 LTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIK 582
S+L +H ++ T ++P Y C C + ++S L +K
Sbjct: 632 NQFSTLTKH---------------KIIHTEEKP----YKCEECGKAFKWSSTLTKHK--- 669
Query: 583 ENHKNIPLALNYIHNGKKSRALSPLSPVAIEQ--TSLKMMQAVGGAPARPTGE--YICNQ 638
IH G+K P E+ + K+ + TGE Y C +
Sbjct: 670 -----------IIHTGEK--------PYKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEK 710
Query: 639 CGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICES 698
CG + + H K H T C +C K F L H IH Y C+
Sbjct: 711 CGKAFNRSSNLIEHKKIH--TGEQPYKCEECGKAFNYSSHLNTHKRIH--TKEQPYKCKE 766
Query: 699 CDKQFTSVDDLQKH 712
C K F +L H
Sbjct: 767 CGKAFNQYSNLTTH 780
Score = 160 bits (405), Expect = 7e-39
Identities = 186/781 (23%), Positives = 272/781 (34%), Gaps = 144/781 (18%)
Query: 453 NEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANP-----AA 507
N HLK+ H++ D + QC ++ + + + ++ H F+N +
Sbjct: 111 NVHLKKDHKSVDECKVHRGGYNGFNQCLPATQ--SKIFLFDKCVKAFHKFSNSNRHKISH 168
Query: 508 KDSNAFFCPHCYMGFLTDSSLEEH------IRQVHCDLSGSRFGSPVLGTPKEPV---VE 558
+ F C C F L +H + C+ G F P + T + + +
Sbjct: 169 TEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEK 228
Query: 559 VYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLK 618
Y+C C +FN +L H K+N+ L GK S L+ I +T K
Sbjct: 229 PYTCEEC--GKVFNWSSRLTTH-KKNYTRYKL-YKCEECGKAFNKSSILTTHKIIRTGEK 284
Query: 619 MMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQES 678
Y C +C + + H K H K C +C K F +
Sbjct: 285 F--------------YKCKECAKAFNQSSNLTEHKKIHPGEKPYK--CEECGKAFNWPST 328
Query: 679 LLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQ 738
L KH IH Y CE C K F +L H F++CT C E F ++
Sbjct: 329 LTKHKRIH--TGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLT 386
Query: 739 LHLAVKHSNEKKVYRCTSCNWDFRNETDLQLH-------------------------VKH 773
H + EKK Y+C C F+ + L H KH
Sbjct: 387 KHKKIH--TEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKH 444
Query: 774 NHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREK 831
N + K +KC CG++F L H I T K Y C+ C KAF L KH K
Sbjct: 445 NRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKH---K 501
Query: 832 HCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQE----------SHNSHDGSEEDVDT 881
E K C G + + + E + T + +H S + + T
Sbjct: 502 KIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIHT 561
Query: 882 SEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFS 941
E Y C+ CG A+T + L H+ I GE YKC C + F
Sbjct: 562 GEKPYKCEECGKAFTQSSNLTTHK----KIHTGEKF------------YKCEECGKAFTQ 605
Query: 942 ENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEE 1001
+ L H + H G K Y C CG+ F TLT+HK+ H++ C C +
Sbjct: 606 SSNLTTHKKIHTGG-KPYKCEECGKAFNQFSTLTKHKIIHTEE-KPYKCEECGKAFKWSS 663
Query: 1002 EFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHV 1061
+H +H + ++C C + + L H H TG
Sbjct: 664 TLTKHKIIHTGEK----PYKCEECGKAFKLSSTLSTHKIIH---TG-------------- 702
Query: 1062 QKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGL 1118
+K YKC C K F +L+ K+ PY C C +S L
Sbjct: 703 EKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPY-KCEECGKAFNYSS------------HL 749
Query: 1119 GQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNH--IQTIHRELVPDSNSTQLKTP 1176
++ + E K C C F S L H I T + P+ + L TP
Sbjct: 750 NTHKRIHTKEQPYK-------CKECGKAFNQYSNLTTHNKIHTGEKLYKPEDVTVILTTP 802
Query: 1177 Q 1177
Q
Sbjct: 803 Q 803
Score = 158 bits (400), Expect = 3e-38
Identities = 169/749 (22%), Positives = 266/749 (35%), Gaps = 129/749 (17%)
Query: 578 NKHIKENHKNIPLALNYI--HNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE-- 633
N H+K++HK++ + +NG + S + + +K +
Sbjct: 111 NVHLKKDHKSVDECKVHRGGYNGFNQCLPATQSKIFLFDKCVKAFHKFSNSNRHKISHTE 170
Query: 634 ---YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMIT 690
+ C +CG + L H H K C +C K F + KH I+
Sbjct: 171 KKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCK--CEKCGKAFNCPSIITKHKRIN--TG 226
Query: 691 STYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKK 750
Y CE C K F L H + + ++C C + F+ + H ++ +K
Sbjct: 227 EKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTG--EK 284
Query: 751 VYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKK 808
Y+C C F ++L H K + E K +KC CG++F L H I T K
Sbjct: 285 FYKCKECAKAFNQSSNLTEHKKIHPGE---KPYKCEECGKAFNWPSTLTKHKRIHTGEKP 341
Query: 809 YNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQES 868
Y C+ C KAF+ L H R K CG E + LT ++
Sbjct: 342 YTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECG----------EAFSRSSNLTKHKKI 391
Query: 869 HNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKG 928
H T + Y C+ CG A+ + L H+L +P
Sbjct: 392 H-----------TEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKP--------------- 425
Query: 929 NYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTG 988
YKC C + F + L +H + H G K Y C +CG+ F LT HK H+
Sbjct: 426 -YKCEECGKAFNWPSTLTKHNRIHTGE-KPYKCEVCGKAFNQFSNLTTHKRIHTAEKPY- 482
Query: 989 NCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQ---- 1044
C C +H ++H + + ++C C + + +L H H
Sbjct: 483 KCEECGKAFSRSSNLTKHKKIHIEKKP----YKCEECGKAFKWSSKLTEHKITHTGEKPY 538
Query: 1045 ------KTGNGSAVQTTGRGQHV-QKLYKCASCLKEFRSKQDLV--KLDINGLPYGLCAG 1095
K N ++ T + H +K YKC C K F +L K G + C
Sbjct: 539 KCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEE 598
Query: 1096 CVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQN 1155
C Q+ NL+ + K GG +C C F S L
Sbjct: 599 CGK------------------AFTQSSNLTTHK-KIHTGGKPYKCEECGKAFNQFSTLTK 639
Query: 1156 HIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVA 1215
H + IH E +K Y+C +C F + H
Sbjct: 640 H-KIIHTE----------------------------EKPYKCEECGKAFKWSSTLTKHKI 670
Query: 1216 NHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHI 1275
H ++ ++C+ C + F + L H I H+ E +KC C F +++ L +H
Sbjct: 671 IHTGEKP--YKCEECGKAFKLSSTLSTHKIIHTGE---KPYKCEKCGKAFNRSSNLIEHK 725
Query: 1276 FSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
G++ Y C +C + F + + L H
Sbjct: 726 KIHTGEQP--YKCEECGKAFNYSSHLNTH 752
Score = 153 bits (386), Expect = 1e-36
Identities = 148/587 (25%), Positives = 219/587 (37%), Gaps = 111/587 (18%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C C + F S++TEHK ++ G C + PS+ + H
Sbjct: 283 EKFYKCKECAKAFNQSSNLTEHK----KIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTG 338
Query: 104 GCDFGEEEGGPGLP-----------------YPCQFCDKSFSRLSYLKHHEQSHSDKLPF 146
+ EE G Y C C ++FSR S L H++ H++K P+
Sbjct: 339 EKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPY 398
Query: 147 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAI 206
KC C + FK H HTG+K Y C EC AF+ L H + HT KPYKC +
Sbjct: 399 KCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEV 458
Query: 207 CRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIA 266
C + F S+L H ++H K KC +C + F +L KH
Sbjct: 459 CGKAFNQFSNLTTHKRIHTAEK----------------PYKCEECGKAFSRSSNLTKH-K 501
Query: 267 ECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELY 326
+ H E P +C C + F + L H + H+GEK C C ++F+ L
Sbjct: 502 KIHIEKKP------YKCEECGKAFKWSSKLTEH-KITHTGEKPYKCEECGKAFNHFSILT 554
Query: 327 SHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRK 384
H H ++P C + T SNL+ + K
Sbjct: 555 KHKRIHTGEKPYKCEECG------------KAFTQSSNLTTHKK--IHTGEKFYKCEECG 600
Query: 385 RAAQQTPDMTGPSS-KQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCL 443
+A Q+ ++T Y C C K F+ + L H K +H + E+ + C+ C
Sbjct: 601 KAFTQSSNLTTHKKIHTGGKPYKCEECGK-AFNQFSTLTKH-KIIHTE--EKPYKCEECG 656
Query: 444 EVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFA 503
+ L +H K +H + P Y+C C + +TL H + H
Sbjct: 657 KAFKWSSTLTKH-KIIHTGEKP-----------YKCEECGKAFKLSSTLSTH-KIIHTGE 703
Query: 504 NPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH-------CDLSGSRFG-SPVLGTPK-- 553
P + C C F S+L EH +++H C+ G F S L T K
Sbjct: 704 KP-------YKCEKCGKAFNRSSNLIEH-KKIHTGEQPYKCEECGKAFNYSSHLNTHKRI 755
Query: 554 EPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKK 600
+ Y C C + FN L H N IH G+K
Sbjct: 756 HTKEQPYKCKECGKA--FNQYSNLTTH------------NKIHTGEK 788
Score = 85.5 bits (210), Expect = 3e-16
Identities = 47/161 (29%), Positives = 77/161 (47%), Gaps = 15/161 (9%)
Query: 43 DEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHG 102
+E + C+ C + F+ S +T+HKI + + P T +H
Sbjct: 646 EEKPYKCEECGKAFKWSSTLTKHKI--------IHTGEKPYKCEECGKAFKLSSTLSTH- 696
Query: 103 EGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRD 162
+ GE+ PY C+ C K+F+R S L H++ H+ + P+KC C + F + +
Sbjct: 697 KIIHTGEK------PYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLN 750
Query: 163 RHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYK 203
H ++HT ++ Y C EC AF++ +L H K HT K YK
Sbjct: 751 THKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLYK 791
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/320 (22%), Positives = 115/320 (35%), Gaps = 41/320 (12%)
Query: 989 NCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLEL--KIHGTFHMQKT 1046
NC + L+ + + ++ C++H R GF C+ S + L K FH
Sbjct: 106 NCEHKNVHLKKDHKSVDECKVH---RGGYNGFN--QCLPATQSKIFLFDKCVKAFHKFSN 160
Query: 1047 GNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPG 1106
N + T + KL+KC C K F L + I C C K+
Sbjct: 161 SNRHKISHTEK-----KLFKCKECGKSFCMLPHLAQHKIIHTRVNFCK-CEKCGKA---- 210
Query: 1107 INVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVP 1166
N P ++ + G C C F S L H + R +
Sbjct: 211 FNCP------------SIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLY 258
Query: 1167 DSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHE 1226
+ S + ++ EK Y+C +C F ++ H H ++ ++
Sbjct: 259 KCEECGKAFNKSSILTTHKIIRTGEK-FYKCKECAKAFNQSSNLTEHKKIHPGEKP--YK 315
Query: 1227 CKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH--IFSAHGQEDK 1284
C+ C + F+ P+ L H H+ E + C C F Q + L H I +A +K
Sbjct: 316 CEECGKAFNWPSTLTKHKRIHTGEK---PYTCEECGKAFNQFSNLTTHKRIHTA----EK 368
Query: 1285 IYDCTQCPQKFFFQTELQNH 1304
Y CT+C + F + L H
Sbjct: 369 FYKCTECGEAFSRSSNLTKH 388
>gi|172072608 zinc finger protein 624 [Homo sapiens]
Length = 865
Score = 195 bits (495), Expect = 3e-49
Identities = 169/717 (23%), Positives = 272/717 (37%), Gaps = 137/717 (19%)
Query: 108 GEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKL 167
G++ PY C C+K+F S L H+++H+ + P++C C + F +H K+
Sbjct: 266 GKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQHKKI 325
Query: 168 HTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERN 227
HTG+K Y C+EC AF S L +H + HT KPY+C +C + F + L+ H ++
Sbjct: 326 HTGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCARLNQHQRIQTGE 385
Query: 228 K------------DGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPN 275
K D S+ E + KC C + F L H + H E P
Sbjct: 386 KPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVH-QKTHTEEKP- 443
Query: 276 EDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--Q 333
QC C + F + T++ N +++H+GEK C+ C +++ + L H+ +H +
Sbjct: 444 -----YQCNECGKSF-KNTTIFNVHQRIHTGEKPFRCNECGKAYRSNSSLIVHIRTHTGE 497
Query: 334 QPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDM 393
+P CN + +++ T + P + K +
Sbjct: 498 KPYECNECGK------AFNRIANFTEHQRIHTGEK-------PYKCNECGKAFINYSCLT 544
Query: 394 TGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLN 453
+ Y C C K S +++ IH + +KP ++C C E +L
Sbjct: 545 VHHRMHTGEKPYKCTECGKAFMRSSSLI-IHQRIHTEEKP---YLCNECGESFRIKSHLT 600
Query: 454 EHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAF 513
H +++H + P Y+C C + L+EH + G +
Sbjct: 601 VH-QRIHTGEKP-----------YKCTDCERAFTKMVNLKEHQKIHTGV--------KPY 640
Query: 514 FCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNS 573
C C F T S L H R T ++P Y C+ C + F +
Sbjct: 641 KCYDCGKSFRTKSYLIVHQR---------------THTGEKP----YKCNECEKA--FTN 679
Query: 574 VLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE 633
+L H + H G+K
Sbjct: 680 TSQLTVHQRR------------HTGEK--------------------------------P 695
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITS-- 691
Y CN+CG +TS F TH +TH T C C K F S + HVT H I S
Sbjct: 696 YKCNECGKVFTSNSGFNTHQRTH--TGEKPFKCNDCGKAF----SQMVHVTEHQKIHSGE 749
Query: 692 TYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKV 751
Y C+ C K F L H + C C + + + LH + H+ E+
Sbjct: 750 KPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQLTLHQRI-HTGERP- 807
Query: 752 YRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKK 808
Y+C C FR +D +H++ + K +KC CG++F + L H H ++
Sbjct: 808 YKCEECGKAFRTNSDFTVHLR---MHTGEKPYKCNECGKAFRSSSSLTVHQRIHQRE 861
Score = 176 bits (445), Expect = 2e-43
Identities = 177/721 (24%), Positives = 274/721 (38%), Gaps = 133/721 (18%)
Query: 377 IPKSRGRKRAAQQTPDMT-GPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQ 435
I K +A +QT ++T G S + Y C C K ++Q H +T +KP +
Sbjct: 247 ICKEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQ-HQRTHTKEKPYE 305
Query: 436 AHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEH 495
C C + L++H K++H + P Y+CN C + ++L H
Sbjct: 306 ---CNECGKTFSQPSYLSQH-KKIHTGEKP-----------YKCNECGKAFIASSSLMVH 350
Query: 496 IRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEP 555
R H P + C C F + L +H R + T ++P
Sbjct: 351 QRI-HTKEKP-------YQCNVCGKSFSQCARLNQHQR---------------IQTGEKP 387
Query: 556 VVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQT 615
Y CS C + F+ KL +H + HNG+K ++
Sbjct: 388 ----YKCSECGKA--FSDKSKLARHQET------------HNGEKPYKCDDCGKAFRNKS 429
Query: 616 SLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPN 675
L + Q +P Y CN+CG + + F H + H T C +C K + +
Sbjct: 430 YLSVHQKTH-TEEKP---YQCNECGKSFKNTTIFNVHQRIH--TGEKPFRCNECGKAYRS 483
Query: 676 QESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKV 735
SL+ H+ H Y C C K F + + +H ++C C + F +
Sbjct: 484 NSSLIVHIRTH--TGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYS 541
Query: 736 SIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTE 795
+ +H + H+ EK Y+CT C F + L + H + + K + C CGESF +
Sbjct: 542 CLTVHHRM-HTGEKP-YKCTECGKAFMRSSSL---IIHQRIHTEEKPYLCNECGESFRIK 596
Query: 796 VELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQK 853
L H I T K Y C C +AF ++ L++H + V K +CG
Sbjct: 597 SHLTVHQRIHTGEKPYKCTDCERAFTKMVNLKEHQKIHTGVKPYKCYDCG---------- 646
Query: 854 EEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRP 913
+ ++ L Q +H T E Y C+ C A+T + L HQ R +P
Sbjct: 647 KSFRTKSYLIVHQRTH-----------TGEKPYKCNECEKAFTNTSQLTVHQRRHTGEKP 695
Query: 914 GESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLT 973
YKCN C + F S +G H +TH G K + C CG+ F ++
Sbjct: 696 ----------------YKCNECGKVFTSNSGFNTHQRTHTGE-KPFKCNDCGKAFSQMVH 738
Query: 974 LTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTL 1033
+TEH+ HS C +C + H + H + + C C + +
Sbjct: 739 VTEHQKIHSGE-KPYKCDVCGKAFRRGSYLTVHWRTHTGEK----PYTCKECGKGCITLS 793
Query: 1034 ELKIHGTFHMQKTGN--------GSAVQTTG------RGQHVQKLYKCASCLKEFRSKQD 1079
+L +H H TG G A +T R +K YKC C K FRS
Sbjct: 794 QLTLHQRIH---TGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSS 850
Query: 1080 L 1080
L
Sbjct: 851 L 851
Score = 145 bits (367), Expect = 2e-34
Identities = 172/733 (23%), Positives = 263/733 (35%), Gaps = 122/733 (16%)
Query: 529 EEHIRQVHC-DLSGSRF----GSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKE 583
+ H+ ++ C ++ GS+ LG + Y CS C + + S+L +H +
Sbjct: 240 DTHLGKIICKEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLI--QHQRT 297
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKY 643
+ K P N GK S LS T K Y CN+CG +
Sbjct: 298 HTKEKPYECNEC--GKTFSQPSYLSQHKKIHTGEK--------------PYKCNECGKAF 341
Query: 644 TSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQF 703
+ S H + H T C C K F L +H I Y C C K F
Sbjct: 342 IASSSLMVHQRIH--TKEKPYQCNVCGKSFSQCARLNQHQRIQ--TGEKPYKCSECGKAF 397
Query: 704 TSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRN 763
+ L +H + ++C C + F +K + +H K E+K Y+C C F+N
Sbjct: 398 SDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVHQ--KTHTEEKPYQCNECGKSFKN 455
Query: 764 ETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAI 821
T +H + + K +C CG+++ + L HI TH+ K Y C C KAF+ I
Sbjct: 456 TTIFNVHQR---IHTGEKPFRCNECGKAYRSNSSLIVHIRTHTGEKPYECNECGKAFNRI 512
Query: 822 ILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDT 881
+H R K CG K + L + H H G
Sbjct: 513 ANFTEHQRIHTGEKPYKCNECG---------KAFINYSCLTVH----HRMHTG------- 552
Query: 882 SEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFS 941
E Y C CG A+ + L HQ +P Y CN C +F
Sbjct: 553 -EKPYKCTECGKAFMRSSSLIIHQRIHTEEKP----------------YLCNECGESFRI 595
Query: 942 ENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEE 1001
++ L H + H G K Y C C F ++ L EH+ H+ + C C +++
Sbjct: 596 KSHLTVHQRIHTGE-KPYKCTDCERAFTKMVNLKEHQKIHT-GVKPYKCYDCGKSFRTKS 653
Query: 1002 EFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHV 1061
+ H + H + ++C C + T+T +L +H H TG
Sbjct: 654 YLIVHQRTHTGEKP----YKCNECEKAFTNTSQLTVHQRRH------------TG----- 692
Query: 1062 QKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQN 1121
+K YKC C K F S N + G P N G +
Sbjct: 693 EKPYKCNECGKVFTSNSGF-----------------NTHQRTHTG-EKPFKCNDCGKAFS 734
Query: 1122 ENLSAIEGKGKVGGLKT-RCSSCNVKFESESELQNHIQTIHRE---LVPDSNSTQLKTPQ 1177
+ + E + G K +C C F S L H +T E + + Q
Sbjct: 735 QMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQ 794
Query: 1178 VSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSP 1237
++ RI + + Y+C +C F D VH+ H ++ ++C C + F S
Sbjct: 795 LTLHQRIHTGE----RPYKCEECGKAFRTNSDFTVHLRMHTGEK--PYKCNECGKAFRSS 848
Query: 1238 AKLQCHLIEHSFE 1250
+ L H H E
Sbjct: 849 SSLTVHQRIHQRE 861
Score = 143 bits (360), Expect = 1e-33
Identities = 126/529 (23%), Positives = 211/529 (39%), Gaps = 81/529 (15%)
Query: 23 TEDGEALDCKKRPEDGEELED-EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDD 81
+E G+A K + +E + E + CD C + F + S ++ H+ + E
Sbjct: 391 SECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVHQKTHTE-------EKP 443
Query: 82 PTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHS 141
C+ S K+ T + + GE+ P+ C C K++ S L H ++H+
Sbjct: 444 YQCN--ECGKSFKNTTIFNVHQRIHTGEK------PFRCNECGKAYRSNSSLIVHIRTHT 495
Query: 142 DKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKP 201
+ P++C C + F + H ++HTG+K Y C+EC AF L +H + HT KP
Sbjct: 496 GEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHRMHTGEKP 555
Query: 202 YKCAICRRGFLSSSSLHGHMQVHERNKD--GSQSGSRMEDWKMKD-------------TQ 246
YKC C + F+ SSSL H ++H K ++ G E +++K
Sbjct: 556 YKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECG---ESFRIKSHLTVHQRIHTGEKPY 612
Query: 247 KCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSG 306
KC+ CE F +L++H + H P +C C + F ++ L+ H ++ H+G
Sbjct: 613 KCTDCERAFTKMVNLKEH-QKIHTGVKP------YKCYDCGKSFRTKSYLIVH-QRTHTG 664
Query: 307 EKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLS 364
EK C+ C ++F +L H H ++P CN G+ + T
Sbjct: 665 EKPYKCNECEKAFTNTSQLTVHQRRHTGEKPYKCNECGKVFTSNSGFNTHQRTHTGEK-- 722
Query: 365 VDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIH 424
P + K +Q + Y C C K F + L +H
Sbjct: 723 -----------PFKCNDCGKAFSQMVHVTEHQKIHSGEKPYKCDVCGK-AFRRGSYLTVH 770
Query: 425 LKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSE 484
+T +KP + C+ C + +L L H +++H + P Y+C C +
Sbjct: 771 WRTHTGEKP---YTCKECGKGCITLSQLTLH-QRIHTGERP-----------YKCEECGK 815
Query: 485 VVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIR 533
+ H+R G + C C F + SSL H R
Sbjct: 816 AFRTNSDFTVHLRMHTG--------EKPYKCNECGKAFRSSSSLTVHQR 856
Score = 135 bits (341), Expect = 2e-31
Identities = 166/704 (23%), Positives = 258/704 (36%), Gaps = 141/704 (20%)
Query: 275 NEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH-- 332
N +C C + F + L+ H ++ H+ EK C+ C ++F L H H
Sbjct: 270 NNKEKPYKCSTCEKAFHYRSLLIQH-QRTHTKEKPYECNECGKTFSQPSYLSQHKKIHTG 328
Query: 333 QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRK-----RAA 387
++P CN + + S+L V + P G+ R
Sbjct: 329 EKPYKCNECGKAFIAS------------SSLMVHQRIHTKEKPYQCNVCGKSFSQCARLN 376
Query: 388 QQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLP 447
Q TG Y C C K FS + L H +T + +KP + C C +
Sbjct: 377 QHQRIQTGEKP------YKCSECGKA-FSDKSKLARHQETHNGEKPYK---CDDCGKAFR 426
Query: 448 SLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAA 507
+ L+ H K H + P YQCN C + + H R G
Sbjct: 427 NKSYLSVHQK-THTEEKP-----------YQCNECGKSFKNTTIFNVHQRIHTG------ 468
Query: 508 KDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTN 567
F C C + ++SSL HIR T ++P Y C+ C
Sbjct: 469 --EKPFRCNECGKAYRSNSSLIVHIRT---------------HTGEKP----YECNECGK 507
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+ FN + +H + IH G+K + I + L + +
Sbjct: 508 A--FNRIANFTEHQR------------IHTGEKPYKCNECGKAFINYSCLTVHHRMH--- 550
Query: 628 ARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTI 685
TGE Y C +CG + S H + H + P L C +C + F + L H I
Sbjct: 551 ---TGEKPYKCTECGKAFMRSSSLIIHQRIHTEEK-PYL-CNECGESFRIKSHLTVHQRI 605
Query: 686 HFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVK 744
H Y C C++ FT + +L++H +HT V ++C C + F +K + +H
Sbjct: 606 H--TGEKPYKCTDCERAFTKMVNLKEHQ-KIHTGVKPYKCYDCGKSFRTKSYLIVHQRT- 661
Query: 745 HSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITT 804
H+ EK Y+C C F N + L +H + + E K +KC CG+ F + H T
Sbjct: 662 HTGEKP-YKCNECEKAFTNTSQLTVHQRRHTGE---KPYKCNECGKVFTSNSGFNTHQRT 717
Query: 805 HS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG--------------TNGAS 848
H+ K + C C KAF ++ + +H + K CG T+
Sbjct: 718 HTGEKPFKCNDCGKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGE 777
Query: 849 EQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRD 908
+ +E + + H + + T E Y C+ CG A+ + H LR
Sbjct: 778 KPYTCKECGKGCITLSQLTLH-------QRIHTGERPYKCEECGKAFRTNSDFTVH-LRM 829
Query: 909 HNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTH 952
H GE YKCN C + F S + L H + H
Sbjct: 830 HT---GEKP------------YKCNECGKAFRSSSSLTVHQRIH 858
Score = 133 bits (334), Expect = 1e-30
Identities = 160/716 (22%), Positives = 255/716 (35%), Gaps = 138/716 (19%)
Query: 601 SRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV 660
S+ + PL Q + + P T E + ++C T ++F +L DT
Sbjct: 187 SQRIIPLKKTPTSQRGFRFESILIPEPGIATEE-LHSRC---QTQEENFTENLNLITDTH 242
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY----YICESCDKQFTSVDDLQKHLLDM 716
L K+ C KE +++ + + S Y C +C+K F L +H
Sbjct: 243 LGKIIC----KEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTH 298
Query: 717 HTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHL 776
+ C C + F + H + H+ EK Y+C C F + L +H + +
Sbjct: 299 TKEKPYECNECGKTFSQPSYLSQHKKI-HTGEKP-YKCNECGKAFIASSSLMVHQR---I 353
Query: 777 ENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCV 834
+ K ++C CG+SF L H I T K Y C C KAF L +H +
Sbjct: 354 HTKEKPYQCNVCGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGE 413
Query: 835 FETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAA 894
K +CG + ++ L+ Q++H T E Y C+ CG +
Sbjct: 414 KPYKCDDCG----------KAFRNKSYLSVHQKTH-----------TEEKPYQCNECGKS 452
Query: 895 YTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLG 954
+ T+ HQ I GE ++CN C + + S + L H++TH G
Sbjct: 453 FKNTTIFNVHQ----RIHTGEKP------------FRCNECGKAYRSNSSLIVHIRTHTG 496
Query: 955 PVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLR 1014
K Y C CG+ F + TEH+ H+ C C + H +MH +
Sbjct: 497 E-KPYECNECGKAFNRIANFTEHQRIHTGEKPY-KCNECGKAFINYSCLTVHHRMHTGEK 554
Query: 1015 NSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEF 1074
++C C + + L IH H + +K Y C C + F
Sbjct: 555 P----YKCTECGKAFMRSSSLIIHQRIHTE-----------------EKPYLCNECGESF 593
Query: 1075 RSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKG 1131
R K L ++ PY C + ++ + +N+ K
Sbjct: 594 RIKSHLTVHQRIHTGEKPYK----CTDCERAFTKMVNLKE----------------HQKI 633
Query: 1132 KVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDE 1191
G +C C F ++S L H +T E
Sbjct: 634 HTGVKPYKCYDCGKSFRTKSYLIVHQRTHTGE---------------------------- 665
Query: 1192 KKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEG 1251
K Y+C +C+ F N + VH H ++ ++C C + F S + H H+ E
Sbjct: 666 -KPYKCNECEKAFTNTSQLTVHQRRHTGEK--PYKCNECGKVFTSNSGFNTHQRTHTGE- 721
Query: 1252 MGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMT 1307
FKC C F Q + +H G +K Y C C + F + L H T
Sbjct: 722 --KPFKCNDCGKAFSQMVHVTEHQKIHSG--EKPYKCDVCGKAFRRGSYLTVHWRT 773
Score = 52.4 bits (124), Expect = 3e-06
Identities = 39/168 (23%), Positives = 67/168 (39%), Gaps = 7/168 (4%)
Query: 1141 SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC 1200
S C + E+ +E N I H + K + + + ++++K Y+C C
Sbjct: 222 SRCQTQEENFTENLNLITDTHLGKIICKEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTC 281
Query: 1201 QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV 1260
+ F+ + H H ++ +EC C +TF P+ L H H+ E +KC
Sbjct: 282 EKAFHYRSLLIQHQRTHTKEKP--YECNECGKTFSQPSYLSQHKKIHTGE---KPYKCNE 336
Query: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQ 1308
C F+ ++ L H ++K Y C C + F L H Q
Sbjct: 337 CGKAFIASSSLMVH--QRIHTKEKPYQCNVCGKSFSQCARLNQHQRIQ 382
>gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens]
Length = 1029
Score = 195 bits (495), Expect = 3e-49
Identities = 188/770 (24%), Positives = 299/770 (38%), Gaps = 136/770 (17%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C C K F+++S+L +H + H+ + P KC C + F + S H++ H+G+K Y C+
Sbjct: 370 YKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKPYKCN 429
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERNK 228
EC AFS+S +L H + HT KPYKC C +GF S L H++ H E K
Sbjct: 430 ECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGLIIHLRRHSGERPYKCNECGK 489
Query: 229 DGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVY 285
SQ+ ++ ++ ++ KC++C++ F + L H H P +C
Sbjct: 490 VFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILH-QRIHSGEKP------YKCDE 542
Query: 286 CHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPS 345
C + F + T L++H +++HS E C C + F + L H H + +
Sbjct: 543 CGKTFAQTTYLIDH-QRLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKK--------- 592
Query: 346 LVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTY 405
T G + +D M P + K Q + Y
Sbjct: 593 --TFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKPY 650
Query: 406 SCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDP 465
C C K +F L +H E + C+ C +V S NL +H +++H + P
Sbjct: 651 ECNECGK-VFILKKSLILH---QRFHTGENLYECKDCGKVFGSNRNLIDH-ERLHNGEKP 705
Query: 466 GLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTD 525
Y+C C + + H + A+ C C F +
Sbjct: 706 -----------YECRECGKTFIMSKSFMVHQKLH--------TQEKAYKCEDCGKAFSYN 746
Query: 526 SSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENH 585
SSL H R++H T ++P + CS C + F+S L +H +
Sbjct: 747 SSLLVH-RRIH--------------TGEKP----FECSECGRA--FSSNRNLIEHKR--- 782
Query: 586 KNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTS 645
IH+G+K Y C++CG +
Sbjct: 783 ---------IHSGEK--------------------------------PYECDECGKCFIL 801
Query: 646 LDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTS 705
S H + H T C C K F + +L+ H IH Y C C K FT
Sbjct: 802 KKSLIGHQRIH--TREKSYKCNDCGKVFSYRSNLIAHQRIH--TGEKPYACSECGKGFTY 857
Query: 706 VDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNET 765
+L +H + C +C++V S ++ +H + H+ EK Y+C C DF
Sbjct: 858 NRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRI-HTGEKP-YKCNECGKDFSQNK 915
Query: 766 DLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF----H 819
+L V H + K ++C C +SF ++ L H I T K Y C CSK F +
Sbjct: 916 NL---VVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKN 972
Query: 820 AIILLEKHLREKHCVFETKTPNCG-TNGASEQVQKEEVELQTLLTNSQES 868
+ + H EK C + T+ Q + +E + L N+ ES
Sbjct: 973 LTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQKIHTIEEFSWLQNTNES 1022
Score = 166 bits (420), Expect = 1e-40
Identities = 169/750 (22%), Positives = 287/750 (38%), Gaps = 117/750 (15%)
Query: 42 EDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSH 101
E + + CD C + F +S H IN ++ G C SS +H
Sbjct: 365 EGKKFYKCDMCCKHFNKIS----HLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNH 420
Query: 102 GEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSR 161
GE+ PY C C K+FS+ +YL +H++ H+ + P+KC C + F
Sbjct: 421 S-----GEK------PYKCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGL 469
Query: 162 DRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHM 221
H++ H+G++ Y C+EC FS++ +L H + H +PYKC C++ F+ SL H
Sbjct: 470 IIHLRRHSGERPYKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQ 529
Query: 222 QVH---------ERNKDGSQSGSRMEDWKMKDTQ---KCSQCEEGFDFPEDLQKHIAECH 269
++H E K +Q+ ++ ++ + KC +C + F + L H H
Sbjct: 530 RIHSGEKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLLH-QRVH 588
Query: 270 PECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHM 329
E + C C ++F +++ ++H +++HS EK C+ C ++F L+ H
Sbjct: 589 TE------KKTFGCKKCGKIFSSKSNFIDH-KRMHSREKPYKCTECGKAFTQSAYLFDHQ 641
Query: 330 DSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAA 387
H ++P CN ++ NL K G R
Sbjct: 642 RLHNGEKPYECNECGKVFILKKSLILHQRFHTGENL--------YECKDCGKVFGSNRNL 693
Query: 388 QQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLP 447
+ + Y C C K S + + +H K L E+A+ C+ C +
Sbjct: 694 -----IDHERLHNGEKPYECRECGKTFIMSKSFM-VHQK---LHTQEKAYKCEDCGKAFS 744
Query: 448 SLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAA 507
+L H +++H + P ++C+ C + L EH R G
Sbjct: 745 YNSSLLVH-RRIHTGEKP-----------FECSECGRAFSSNRNLIEHKRIHSG------ 786
Query: 508 KDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTN 567
+ C C F+ SL H +++H + Y C+ C
Sbjct: 787 --EKPYECDECGKCFILKKSLIGH-QRIHTR------------------EKSYKCNDCGK 825
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+ S L +A IH G+K A S +L Q +
Sbjct: 826 VFSYRSNL--------------IAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGE 871
Query: 628 ARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
Y C+ C TS + H + H T C +C K+F ++L+ H +H
Sbjct: 872 K----TYECHVCRKVLTSSRNLMVHQRIH--TGEKPYKCNECGKDFSQNKNLVVHQRMH- 924
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSN 747
Y C+ C K FTS +L H + C C +VF + ++ +H + H++
Sbjct: 925 -TGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNLTVHQKI-HTD 982
Query: 748 EKKVYRCTSCNWDFRNETDLQLHVKHNHLE 777
EK C +F ++L L K + +E
Sbjct: 983 EKPC-ECDVSEKEFSQTSNLHLQQKIHTIE 1011
Score = 156 bits (395), Expect = 1e-37
Identities = 189/817 (23%), Positives = 276/817 (33%), Gaps = 177/817 (21%)
Query: 170 GDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKD 229
G K Y C C F++ HL H + HT KP+KC C +GF+ SSL H++ H K
Sbjct: 366 GKKFYKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKP 425
Query: 230 GSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHEL 289
KC++C + F L H H P +C C +
Sbjct: 426 ----------------YKCNECGKAFSQSAYLLNH-QRIHTGEKP------YKCKECGKG 462
Query: 290 FVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLV 347
F + L+ H+ + HSGE+ C+ C + F L H H ++P CN ++
Sbjct: 463 FYRHSGLIIHLRR-HSGERPYKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFIL 521
Query: 348 TVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSC 407
+ + P K AQ T + A+ Y C
Sbjct: 522 KKSL-------------ILHQRIHSGEKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKC 568
Query: 408 IYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGL 467
C K S ++L +H + +H +K + C+ C ++ S N +H K++H + P
Sbjct: 569 KECGKVFIRSKSLL-LHQR-VHTEK--KTFGCKKCGKIFSSKSNFIDH-KRMHSREKP-- 621
Query: 468 IVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSS 527
Y+C C + L +H R +G + C C F+ S
Sbjct: 622 ---------YKCTECGKAFTQSAYLFDHQRLHNG--------EKPYECNECGKVFILKKS 664
Query: 528 LEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKN 587
L H RF + +Y C C +F S L H +
Sbjct: 665 LILH----------QRFHTGE---------NLYECKDC--GKVFGSNRNLIDHER----- 698
Query: 588 IPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLD 647
+HNG+K Y C +CG +
Sbjct: 699 -------LHNGEKP--------------------------------YECRECGKTFIMSK 719
Query: 648 SFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVD 707
SF H K H K C C K F SLL H IH + C C + F+S
Sbjct: 720 SFMVHQKLHTQEKAYK--CEDCGKAFSYNSSLLVHRRIH--TGEKPFECSECGRAFSSNR 775
Query: 708 DLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDL 767
+L +H + C C + F K S+ H + H+ EK Y+C C F ++L
Sbjct: 776 NLIEHKRIHSGEKPYECDECGKCFILKKSLIGHQRI-HTREKS-YKCNDCGKVFSYRSNL 833
Query: 768 QLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLE 825
+ H + K + C CG+ F L H HS K Y C C K + L
Sbjct: 834 ---IAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLM 890
Query: 826 KHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPM 885
H R K CG + S N + + + T E
Sbjct: 891 VHQRIHTGEKPYKCNECGKDF---------------------SQNKNLVVHQRMHTGEKP 929
Query: 886 YGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGL 945
Y CD C ++T + L HQ I GE Y CN CS+ F L
Sbjct: 930 YECDKCRKSFTSKRNLVGHQ----RIHTGEKP------------YGCNDCSKVFRQRKNL 973
Query: 946 REHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHS 982
H + H K C + + F L + H+
Sbjct: 974 TVHQKIHTDE-KPCECDVSEKEFSQTSNLHLQQKIHT 1009
Score = 154 bits (390), Expect = 4e-37
Identities = 168/705 (23%), Positives = 257/705 (36%), Gaps = 120/705 (17%)
Query: 400 QAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQV 459
+ K Y C C K F+ ++ L H + +KP H C+ C + +L HL+
Sbjct: 365 EGKKFYKCDMCCKH-FNKISHLINHRRIHTGEKP---HKCKECGKGFIQRSSLLMHLRN- 419
Query: 460 HEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCY 519
H + P Y+CN C + + L H R G + C C
Sbjct: 420 HSGEKP-----------YKCNECGKAFSQSAYLLNHQRIHTG--------EKPYKCKECG 460
Query: 520 MGFLTDSSLEEHIRQ------VHCDLSGSRFGSPVLGTPKEPV---VEVYSCSYCTNSPI 570
GF S L H+R+ C+ G F + + E Y C+ C + I
Sbjct: 461 KGFYRHSGLIIHLRRHSGERPYKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFI 520
Query: 571 FNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARP 630
L L++ I H+G+K + T L Q + A
Sbjct: 521 LKKSLILHQRI--------------HSGEKPYKCDECGKTFAQTTYLIDHQRLHSAE--- 563
Query: 631 TGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMIT 690
Y C +CG + S H + H T C +C K F ++ + + H +H
Sbjct: 564 -NPYKCKECGKVFIRSKSLLLHQRVH--TEKKTFGCKKCGKIFSSKSNFIDHKRMHSR-- 618
Query: 691 STYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKK 750
Y C C K FT L H + + C C +VF K S+ LH H+ E
Sbjct: 619 EKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKSLILHQRF-HTGEN- 676
Query: 751 VYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKK 808
+Y C C F + +L + H L N K ++C CG++F H + T K
Sbjct: 677 LYECKDCGKVFGSNRNL---IDHERLHNGEKPYECRECGKTFIMSKSFMVHQKLHTQEKA 733
Query: 809 YNCKFCSKAF--HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQ 866
Y C+ C KAF ++ +L+ + + FE CG +S + N
Sbjct: 734 YKCEDCGKAFSYNSSLLVHRRIHTGEKPFECS--ECGRAFSSNR-------------NLI 778
Query: 867 ESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELI 926
E H G E Y CD CG + ++ L HQ +
Sbjct: 779 EHKRIHSG--------EKPYECDECGKCFILKKSLIGHQ----------------RIHTR 814
Query: 927 KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLD 986
+ +YKCN C + F + L H + H G K Y C CG+ F L EH+ HS
Sbjct: 815 EKSYKCNDCGKVFSYRSNLIAHQRIHTGE-KPYACSECGKGFTYNRNLIEHQRIHSGE-K 872
Query: 987 TGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM--- 1043
T C +C+ L S + H ++H + ++C C + + L +H H
Sbjct: 873 TYECHVCRKVLTSSRNLMVHQRIHTGEKP----YKCNECGKDFSQNKNLVVHQRMHTGEK 928
Query: 1044 -------QKTGNGSAVQTTGRGQHV-QKLYKCASCLKEFRSKQDL 1080
+K+ + H +K Y C C K FR +++L
Sbjct: 929 PYECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNL 973
Score = 145 bits (365), Expect = 3e-34
Identities = 181/771 (23%), Positives = 272/771 (35%), Gaps = 155/771 (20%)
Query: 541 GSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKK 600
GS ++GT + + Y C C FN + L H + IH G+K
Sbjct: 354 GSAISESLIGTEGK---KFYKCDMCCKH--FNKISHLINHRR------------IHTGEK 396
Query: 601 SRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTV 660
I+++SL +M + +P Y CN+CG ++ H + H T
Sbjct: 397 PHKCKECGKGFIQRSSL-LMHLRNHSGEKP---YKCNECGKAFSQSAYLLNHQRIH--TG 450
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C +C K F L+ H+ H Y C C K F+ L H
Sbjct: 451 EKPYKCKECGKGFYRHSGLIIHLRRHS--GERPYKCNECGKVFSQNAYLIDHQRLHKGEE 508
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
++C CQ+ F K S+ LH + HS EK Y+C C F T L + H L +
Sbjct: 509 PYKCNKCQKAFILKKSLILHQRI-HSGEKP-YKCDECGKTFAQTTYL---IDHQRLHSAE 563
Query: 781 KVHKCIFCGESFGTEVELQCHITTHSKK--YNCKFCSKAFHAIILLEKHLREKHCVFETK 838
+KC CG+ F L H H++K + CK C K F
Sbjct: 564 NPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIF-------------------- 603
Query: 839 TPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTME 898
S S+ + + + E Y C CG A+T
Sbjct: 604 -----------------------------SSKSNFIDHKRMHSREKPYKCTECGKAFTQS 634
Query: 899 TLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKH 958
L +HQ R HN GE Y+CN C + F + L H + H G
Sbjct: 635 AYLFDHQ-RLHN---GEKP------------YECNECGKVFILKKSLILHQRFHTGE-NL 677
Query: 959 YMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLT 1018
Y C CG+ F S L +H+ H+ CR C + F+ H ++H +
Sbjct: 678 YECKDCGKVFGSNRNLIDHERLHNGEKPY-ECRECGKTFIMSKSFMVHQKLHTQEK---- 732
Query: 1019 GFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQ 1078
++C C + + L +H H TG +K ++C+ C + F S +
Sbjct: 733 AYKCEDCGKAFSYNSSLLVHRRIH------------TG-----EKPFECSECGRAFSSNR 775
Query: 1079 DLV---KLDINGLPYGL--CAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV 1133
+L+ ++ PY C C L KS L ++ + E K
Sbjct: 776 NLIEHKRIHSGEKPYECDECGKCFILKKS---------------LIGHQRIHTREKSYK- 819
Query: 1134 GGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKK 1193
C+ C F S L H Q IH P + S K + +K
Sbjct: 820 ------CNDCGKVFSYRSNLIAH-QRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEK 872
Query: 1194 TYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMG 1253
TY+C C+ V + ++ VH H ++ ++C C + F L H H+ E
Sbjct: 873 TYECHVCRKVLTSSRNLMVHQRIHTGEK--PYKCNECGKDFSQNKNLVVHQRMHTGE--- 927
Query: 1254 GTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
++C C F L H G +K Y C C + F + L H
Sbjct: 928 KPYECDKCRKSFTSKRNLVGHQRIHTG--EKPYGCNDCSKVFRQRKNLTVH 976
Score = 135 bits (341), Expect = 2e-31
Identities = 157/678 (23%), Positives = 247/678 (36%), Gaps = 142/678 (20%)
Query: 477 YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH 536
Y+C+ C + N ++ L H R G C C GF+ SSL H+R
Sbjct: 370 YKCDMCCKHFNKISHLINHRRIHTG--------EKPHKCKECGKGFIQRSSLLMHLR--- 418
Query: 537 CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIH 596
+ SG + Y C+ C + F+ L H + IH
Sbjct: 419 -NHSGEK---------------PYKCNECGKA--FSQSAYLLNHQR------------IH 448
Query: 597 NGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLK 654
G+K + L + R +GE Y CN+CG ++ H +
Sbjct: 449 TGEKPYKCKECGKGFYRHSGLIIHLR------RHSGERPYKCNECGKVFSQNAYLIDHQR 502
Query: 655 THLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLL 714
H K C +C K F ++SL+ H IH Y C+ C K F L H
Sbjct: 503 LHKGEEPYK--CNKCQKAFILKKSLILHQRIHS--GEKPYKCDECGKTFAQTTYLIDHQR 558
Query: 715 DMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHN 774
++C C +VF S+ LH V EKK + C C F ++++ + H
Sbjct: 559 LHSAENPYKCKECGKVFIRSKSLLLHQRVH--TEKKTFGCKKCGKIFSSKSNF---IDHK 613
Query: 775 HLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAF--HAIILLEKHLRE 830
+ ++ K +KC CG++F L H H+ K Y C C K F ++L +
Sbjct: 614 RMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKSLILHQRFHT 673
Query: 831 KHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSE-----------EDV 879
++E K +CG S + + L N ++ + + + + +
Sbjct: 674 GENLYECK--DCGKVFGSNRNLIDHERLH----NGEKPYECRECGKTFIMSKSFMVHQKL 727
Query: 880 DTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTF 939
T E Y C+ CG A++ + L H+ I GE ++C+ C R F
Sbjct: 728 HTQEKAYKCEDCGKAFSYNSSLLVHR----RIHTGEKP------------FECSECGRAF 771
Query: 940 FSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKS--------------- 984
S L EH + H G K Y C CG+ F +L H+ H++
Sbjct: 772 SSNRNLIEHKRIHSGE-KPYECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVFSYR 830
Query: 985 --------LDTGN----CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTST 1032
+ TG C C +EH ++H + + C VC + +TS+
Sbjct: 831 SNLIAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKT----YECHVCRKVLTSS 886
Query: 1033 LELKIHGTFHM-----------QKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV 1081
L +H H + + R +K Y+C C K F SK++LV
Sbjct: 887 RNLMVHQRIHTGEKPYKCNECGKDFSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLV 946
Query: 1082 ---KLDINGLPYGLCAGC 1096
++ PYG C C
Sbjct: 947 GHQRIHTGEKPYG-CNDC 963
Score = 100 bits (250), Expect = 7e-21
Identities = 130/557 (23%), Positives = 198/557 (35%), Gaps = 87/557 (15%)
Query: 777 ENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFE 836
E QG+ K + +FG+ + T K Y C C K F+ I L H R
Sbjct: 338 EKQGQKWKELGDSLTFGSAISESLIGTEGKKFYKCDMCCKHFNKISHLINHRRIHTGEKP 397
Query: 837 TKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYT 896
K CG K ++ +LL + + +H G E Y C+ CG A++
Sbjct: 398 HKCKECG---------KGFIQRSSLLMHLR----NHSG--------EKPYKCNECGKAFS 436
Query: 897 METLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPV 956
L NHQ I GE YKC C + F+ +GL H++ H G
Sbjct: 437 QSAYLLNHQ----RIHTGEKP------------YKCKECGKGFYRHSGLIIHLRRHSGE- 479
Query: 957 KHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNS 1016
+ Y C CG+ F L +H+ H K + C C+ ++ + H ++H +
Sbjct: 480 RPYKCNECGKVFSQNAYLIDHQRLH-KGEEPYKCNKCQKAFILKKSLILHQRIH----SG 534
Query: 1017 LTGFRCVVCMQTVTSTLELKIHGTFHMQKTG-----------NGSAVQTTGRGQHVQKLY 1065
++C C +T T L H H + ++ R +K +
Sbjct: 535 EKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTF 594
Query: 1066 KCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNE 1122
C C K F SK + + ++ PY C K+ + + + L E
Sbjct: 595 GCKKCGKIFSSKSNFIDHKRMHSREKPY----KCTECGKAFTQSAYL---FDHQRLHNGE 647
Query: 1123 NLSAIEGKGKVGGLKT---------------RCSSCNVKFESESELQNHIQTIHRELVPD 1167
GKV LK C C F S L +H + +H P
Sbjct: 648 KPYECNECGKVFILKKSLILHQRFHTGENLYECKDCGKVFGSNRNLIDH-ERLHNGEKPY 706
Query: 1168 SNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHEC 1227
KT +S + ++K Y+C C F + VH H ++ EC
Sbjct: 707 ECRECGKTFIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPF--EC 764
Query: 1228 KLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYD 1287
C + F S L H HS E ++C C F+ L H H +E K Y
Sbjct: 765 SECGRAFSSNRNLIEHKRIHSGE---KPYECDECGKCFILKKSLIGH-QRIHTRE-KSYK 819
Query: 1288 CTQCPQKFFFQTELQNH 1304
C C + F +++ L H
Sbjct: 820 CNDCGKVFSYRSNLIAH 836
Score = 98.6 bits (244), Expect = 3e-20
Identities = 57/209 (27%), Positives = 101/209 (48%), Gaps = 24/209 (11%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K F+ L H++ HS + ++C C ++ R+ H ++HTG+K Y C
Sbjct: 845 PYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRIHTGEKPYKC 904
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+EC FS++ +L +H + HT KPY+C CR+ F S +L GH ++H K
Sbjct: 905 NECGKDFSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEK-------- 956
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
C+ C + F ++L H + H + P E C + F +TS
Sbjct: 957 --------PYGCNDCSKVFRQRKNLTVH-QKIHTDEKPCE------CDVSEKEF-SQTSN 1000
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEEL 325
++ +++H+ E+ + +ES ++++
Sbjct: 1001 LHLQQKIHTIEEFSWLQNTNESKIEIQKI 1029
>gi|54291708 zinc finger protein 780B [Homo sapiens]
Length = 833
Score = 191 bits (485), Expect = 4e-48
Identities = 186/741 (25%), Positives = 277/741 (37%), Gaps = 135/741 (18%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C+ C K FS S L H+ H+ + P+KC C + F+ RH K HTG+K + C
Sbjct: 164 PYECKECGKYFSCGSNLIQHQSIHTGEKPYKCKECGKAFQLHIQLTRHQKFHTGEKTFEC 223
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERN 227
EC AF+ L H HT K ++C C + F SS+L H +H E
Sbjct: 224 KECGKAFNLPTQLNRHKNIHTVKKLFECKECGKSFNRSSNLTQHQSIHAGVKPYQCKECG 283
Query: 228 KDGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
K ++ + ++ K+ +K C +CE F + L +H C + +C
Sbjct: 284 KAFNRGSNLIQHQKIHSNEKPFVCRECEMAFRYHYQLIEH-------CRIHTGEKPFECK 336
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN 342
C + F T L+ H +++H GEK C C ++F + +L H + H ++P C
Sbjct: 337 ECRKAFTLLTKLVRH-QKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKECG 395
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
S SNL S + P
Sbjct: 396 ------------KSFNRSSNLIQHQSIHADVKP--------------------------- 416
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K F+ A L H K +KP +C+ C Y L +H Q+H
Sbjct: 417 --YECKECGKG-FNRGANLIQHQKIHSNEKP---FVCRECEMAFRYHYQLIQHC-QIHTG 469
Query: 463 QDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGF 522
P ++C C + + L L H G F C C F
Sbjct: 470 GKP-----------FECKECGKAFSLLTQLARHKNIHTG--------EKPFECKDCGKAF 510
Query: 523 LTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIK 582
S+L +H + +H T ++P Y C C + F L+L++H K
Sbjct: 511 NRGSNLVQH-QSIH--------------TGEKP----YECKECGKA--FRLHLQLSQHEK 549
Query: 583 ENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPA------------RP 630
+ P GK R S L+ T K + A
Sbjct: 550 THTGEKPFECK--ECGKFFRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKFH 607
Query: 631 TGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFM 688
TGE + C +CG ++ H H T C +C K F +L++H +IH
Sbjct: 608 TGEKPFECKECGKAFSLHTQLNHHKNIH--TGEKPFKCKECGKSFNRVSNLVQHQSIHAG 665
Query: 689 ITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNE 748
+ Y C+ C K F+ V +L +H + F C C++ F + H + H+ E
Sbjct: 666 VKP--YECKECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQLTEHYRI-HTGE 722
Query: 749 KKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESF--GTEVELQCHITTHS 806
K + C C F T L +H + K KC CG++F G+ + I T
Sbjct: 723 KP-FECKECGKAFGLLTQL---AQHQIIHTGEKPFKCKECGKAFNRGSNLVQPQSIHTGE 778
Query: 807 KKYNCKFCSKAFHAIILLEKH 827
K Y CK C KAF + L H
Sbjct: 779 KPYECKECGKAFRLHLQLSLH 799
Score = 139 bits (349), Expect = 2e-32
Identities = 163/701 (23%), Positives = 255/701 (36%), Gaps = 96/701 (13%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y C +CG ++ + H H T C +C K F L +H H
Sbjct: 165 YECKECGKYFSCGSNLIQHQSIH--TGEKPYKCKECGKAFQLHIQLTRHQKFH--TGEKT 220
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFV-FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVY 752
+ C+ C K F L +H ++HT F C C + F+ ++ H ++ H+ K Y
Sbjct: 221 FECKECGKAFNLPTQLNRHK-NIHTVKKLFECKECGKSFNRSSNLTQHQSI-HAGVKP-Y 277
Query: 753 RCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVEL--QCHITTHSKKYN 810
+C C F ++L ++H + + K C C +F +L C I T K +
Sbjct: 278 QCKECGKAFNRGSNL---IQHQKIHSNEKPFVCRECEMAFRYHYQLIEHCRIHTGEKPFE 334
Query: 811 CKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHN 870
CK C KAF LL K +R + K C G + L N H
Sbjct: 335 CKECRKAF---TLLTKLVRHQKIHMGEKPFECRECGKAFS-----------LLNQLNRH- 379
Query: 871 SHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRP------------GESAI 918
+++ T E + C CG ++ + L HQ +++P G + I
Sbjct: 380 ------KNIHTGEKPFECKECGKSFNRSSNLIQHQSIHADVKPYECKECGKGFNRGANLI 433
Query: 919 VKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHK 978
+K + + C C F L +H Q H G K + C CG+ F L L HK
Sbjct: 434 QHQKIHSNEKPFVCRECEMAFRYHYQLIQHCQIHTGG-KPFECKECGKAFSLLTQLARHK 492
Query: 979 VTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
H+ C+ C ++H +H + + C C + L+L H
Sbjct: 493 NIHTGEKPF-ECKDCGKAFNRGSNLVQHQSIHTGEKP----YECKECGKAFRLHLQLSQH 547
Query: 1039 GTFHMQKTG-----------NGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLD 1084
H + GS + +K ++C C K FR L+ K
Sbjct: 548 EKTHTGEKPFECKECGKFFRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKFH 607
Query: 1085 INGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCN 1144
P+ C K+ S L ++N+ G +C C
Sbjct: 608 TGEKPFE----CKECGKAFSLHTQ---------LNHHKNIHT-------GEKPFKCKECG 647
Query: 1145 VKFESESELQNHIQTIHRELVP-DSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMV 1203
F S L H Q+IH + P + +VS + + + S K + C +C+
Sbjct: 648 KSFNRVSNLVQH-QSIHAGVKPYECKECGKGFSRVSNLIQHQKTHSSAKP-FVCKECRKT 705
Query: 1204 FYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFT 1263
F + + H H ++ ECK C + F +L H I H+ E FKC C
Sbjct: 706 FRYHYQLTEHYRIHTGEKPF--ECKECGKAFGLLTQLAQHQIIHTGE---KPFKCKECGK 760
Query: 1264 VFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
F + + L Q S H E K Y+C +C + F +L H
Sbjct: 761 AFNRGSNLVQP-QSIHTGE-KPYECKECGKAFRLHLQLSLH 799
Score = 137 bits (345), Expect = 7e-32
Identities = 175/798 (21%), Positives = 274/798 (34%), Gaps = 171/798 (21%)
Query: 196 HTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGF 255
H ++KPY+C C + F S+L H +H K KC +C + F
Sbjct: 159 HNTHKPYECKECGKYFSCGSNLIQHQSIHTGEKP----------------YKCKECGKAF 202
Query: 256 DFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSIC 315
L +H ++ H+GEK C C
Sbjct: 203 QLHIQLTRH------------------------------------QKFHTGEKTFECKEC 226
Query: 316 SESFHTVEELYSHMDSHQQPE--SCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEA 373
++F+ +L H + H + C S SNL+ S
Sbjct: 227 GKAFNLPTQLNRHKNIHTVKKLFECKECGK------------SFNRSSNLTQHQSIHAGV 274
Query: 374 APPIPKSRGR--KRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLD 431
P K G+ R + S+++ V C + + + +IH +
Sbjct: 275 KPYQCKECGKAFNRGSNLIQHQKIHSNEKPFVCRECEMAFRYHYQLIEHCRIHTG----E 330
Query: 432 KPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNT 491
KP + C+ C + L L H K +H + P ++C C + + LN
Sbjct: 331 KPFE---CKECRKAFTLLTKLVRHQK-IHMGEKP-----------FECRECGKAFSLLNQ 375
Query: 492 LQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGT 551
L H G F C C F S+L +H + +H D
Sbjct: 376 LNRHKNIHTG--------EKPFECKECGKSFNRSSNLIQH-QSIHAD------------- 413
Query: 552 PKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVA 611
V+ Y C C FN L +H K IH+ +K P
Sbjct: 414 -----VKPYECKECGKG--FNRGANLIQHQK------------IHSNEK-----PFVCRE 449
Query: 612 IEQTSLKMMQAVGGAPARPTGE-YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCN 670
E Q + G+ + C +CG ++ L H H T C C
Sbjct: 450 CEMAFRYHYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIH--TGEKPFECKDCG 507
Query: 671 KEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEV 730
K F +L++H +IH Y C+ C K F L +H F C C +
Sbjct: 508 KAFNRGSNLVQHQSIH--TGEKPYECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKF 565
Query: 731 FDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLH-VKHNHLENQGKVHKCIFCG 789
F ++ H ++ H+ KK + C C FR L +H ++H K +C CG
Sbjct: 566 FRRGSNLNQHRSI-HTG-KKPFECKECGKAFR----LHMHLIRHQKFHTGEKPFECKECG 619
Query: 790 ESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCV--FETKTPNCGTN 845
++F +L H H+ K + CK C K+F+ + L +H V +E K G +
Sbjct: 620 KAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYECKECGKGFS 679
Query: 846 GASEQVQKEEVELQT---LLTNSQESHNSHDGSEED--VDTSEPMYGCDICGAAYTMETL 900
S +Q ++ + +++ H E + T E + C CG A+ + T
Sbjct: 680 RVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQLTEHYRIHTGEKPFECKECGKAFGLLTQ 739
Query: 901 LQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYM 960
L HQ+ I GE +KC C + F + L + H G K Y
Sbjct: 740 LAQHQI----IHTGEKP------------FKCKECGKAFNRGSNLVQPQSIHTGE-KPYE 782
Query: 961 CPICGERFPSLLTLTEHK 978
C CG+ F L L+ H+
Sbjct: 783 CKECGKAFRLHLQLSLHQ 800
Score = 134 bits (338), Expect = 4e-31
Identities = 163/687 (23%), Positives = 245/687 (35%), Gaps = 102/687 (14%)
Query: 637 NQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYIC 696
NQ Y + ++ TH +T P C +C K F +L++H +IH Y C
Sbjct: 140 NQKIISYEEMPAY-THASPIHNTHKP-YECKECGKYFSCGSNLIQHQSIH--TGEKPYKC 195
Query: 697 ESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTS 756
+ C K F L +H F C C + F+ + H + KK++ C
Sbjct: 196 KECGKAFQLHIQLTRHQKFHTGEKTFECKECGKAFNLPTQLNRHKNIH--TVKKLFECKE 253
Query: 757 CNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFC 814
C F ++L +H + K ++C CG++F L H HS K + C+ C
Sbjct: 254 CGKSFNRSSNL---TQHQSIHAGVKPYQCKECGKAFNRGSNLIQHQKIHSNEKPFVCREC 310
Query: 815 SKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDG 874
AF L +H R G KE + TLLT H G
Sbjct: 311 EMAFRYHYQLIEHCRIH-------------TGEKPFECKECRKAFTLLTKLVRHQKIHMG 357
Query: 875 SEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNV 934
E + C CG A+++ L H+ NI GE ++C
Sbjct: 358 --------EKPFECRECGKAFSLLNQLNRHK----NIHTGEKP------------FECKE 393
Query: 935 CSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICK 994
C ++F + L +H H VK Y C CG+ F L +H+ HS CR C+
Sbjct: 394 CGKSFNRSSNLIQHQSIH-ADVKPYECKECGKGFNRGANLIQHQKIHSNEKPFV-CRECE 451
Query: 995 MPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQT 1054
M + + ++HCQ+H + F C C + + +L H H
Sbjct: 452 MAFRYHYQLIQHCQIHTGGKP----FECKECGKAFSLLTQLARHKNIH------------ 495
Query: 1055 TGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGL--CAGCVNLSKSASPGINV 1109
TG +K ++C C K F +LV+ + PY C L S
Sbjct: 496 TG-----EKPFECKDCGKAFNRGSNLVQHQSIHTGEKPYECKECGKAFRLHLQLSQHEKT 550
Query: 1110 PPGTN-----------RPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQ 1158
G R G N++ S GK C C F L H Q
Sbjct: 551 HTGEKPFECKECGKFFRRGSNLNQHRSIHTGKKPF-----ECKECGKAFRLHMHLIRH-Q 604
Query: 1159 TIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHM 1218
H P K + + +K ++C +C F ++ H + H
Sbjct: 605 KFHTGEKPFECKECGKAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHA 664
Query: 1219 IDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFS 1277
G+ +ECK C + F + L H HS F C C F +L +H +
Sbjct: 665 ---GVKPYECKECGKGFSRVSNLIQHQKTHS---SAKPFVCKECRKTFRYHYQLTEH-YR 717
Query: 1278 AHGQEDKIYDCTQCPQKFFFQTELQNH 1304
H E K ++C +C + F T+L H
Sbjct: 718 IHTGE-KPFECKECGKAFGLLTQLAQH 743
Score = 125 bits (314), Expect = 3e-28
Identities = 71/226 (31%), Positives = 103/226 (45%), Gaps = 26/226 (11%)
Query: 115 GLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 174
G P+ C+ C K+FS L+ L H+ H+ + PF+C C + F + +H +HTG+K Y
Sbjct: 470 GKPFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCGKAFNRGSNLVQHQSIHTGEKPY 529
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSG 234
C EC AF L H KTHT KP++C C + F S+L+ H +H K
Sbjct: 530 ECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKFFRRGSNLNQHRSIHTGKK------ 583
Query: 235 SRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEET 294
+C +C + F L +H + H P +C C + F T
Sbjct: 584 ----------PFECKECGKAFRLHMHLIRH-QKFHTGEKP------FECKECGKAFSLHT 626
Query: 295 SLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQ--QPESC 338
L NH + +H+GEK C C +SF+ V L H H +P C
Sbjct: 627 QL-NHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYEC 671
Score = 122 bits (307), Expect = 2e-27
Identities = 151/687 (21%), Positives = 239/687 (34%), Gaps = 129/687 (18%)
Query: 455 HLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFF 514
H +H P Y+C C + + + L +H G +
Sbjct: 154 HASPIHNTHKP-----------YECKECGKYFSCGSNLIQHQSIHTG--------EKPYK 194
Query: 515 CPHCYMGFLTDSSLEEHIR------QVHCDLSGSRFGSPV-LGTPKE--PVVEVYSCSYC 565
C C F L H + C G F P L K V +++ C C
Sbjct: 195 CKECGKAFQLHIQLTRHQKFHTGEKTFECKECGKAFNLPTQLNRHKNIHTVKKLFECKEC 254
Query: 566 TNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGG 625
S FN L +H IH G K ++L Q +
Sbjct: 255 GKS--FNRSSNLTQH------------QSIHAGVKPYQCKECGKAFNRGSNLIQHQKIH- 299
Query: 626 APARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTI 685
+ +P ++C +C + H + H T C +C K F L++H I
Sbjct: 300 SNEKP---FVCRECEMAFRYHYQLIEHCRIH--TGEKPFECKECRKAFTLLTKLVRHQKI 354
Query: 686 HFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVK 744
H + + C C K F+ ++ L +H ++HT F C C + F+ ++ H ++
Sbjct: 355 H--MGEKPFECRECGKAFSLLNQLNRHK-NIHTGEKPFECKECGKSFNRSSNLIQHQSI- 410
Query: 745 HSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVEL--QCHI 802
H++ K Y C C F +L ++H + + K C C +F +L C I
Sbjct: 411 HADVKP-YECKECGKGFNRGANL---IQHQKIHSNEKPFVCRECEMAFRYHYQLIQHCQI 466
Query: 803 TTHSKKYNCKFCSKAFHAIILLEKH--LREKHCVFETKTPNCGTNGASEQVQKEEV---- 856
T K + CK C KAF + L +H + FE K N S VQ + +
Sbjct: 467 HTGGKPFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCGKAFNRGSNLVQHQSIHTGE 526
Query: 857 ------------ELQTLLTNSQESH-----------------NSHDGSEEDVDTSEPMYG 887
L L+ +++H S+ + T + +
Sbjct: 527 KPYECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKFFRRGSNLNQHRSIHTGKKPFE 586
Query: 888 CDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELI------------KGNYKCNVC 935
C CG A+ + L HQ +P E K L + +KC C
Sbjct: 587 CKECGKAFRLHMHLIRHQKFHTGEKPFECKECGKAFSLHTQLNHHKNIHTGEKPFKCKEC 646
Query: 936 SRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKM 995
++F + L +H H G VK Y C CG+ F + L +H+ THS S C+ C+
Sbjct: 647 GKSFNRVSNLVQHQSIHAG-VKPYECKECGKGFSRVSNLIQHQKTHS-SAKPFVCKECRK 704
Query: 996 PLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTT 1055
+ + EH ++H + F C C + +L H H TG
Sbjct: 705 TFRYHYQLTEHYRIHTGEK----PFECKECGKAFGLLTQLAQHQIIH---TG-------- 749
Query: 1056 GRGQHVQKLYKCASCLKEFRSKQDLVK 1082
+K +KC C K F +LV+
Sbjct: 750 ------EKPFKCKECGKAFNRGSNLVQ 770
Score = 109 bits (273), Expect = 2e-23
Identities = 66/231 (28%), Positives = 102/231 (44%), Gaps = 26/231 (11%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
P+ C+ C K+FS + L HH+ H+ + PFKC C + F + +H +H G K Y C
Sbjct: 612 PFECKECGKAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYEC 671
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
EC FSR +L H KTH+S KP+ C CR+ F L H ++H K
Sbjct: 672 KECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQLTEHYRIHTGEK-------- 723
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+C +C + F L +H H P +C C + F ++L
Sbjct: 724 --------PFECKECGKAFGLLTQLAQH-QIIHTGEKP------FKCKECGKAFNRGSNL 768
Query: 297 MNHMEQVHSGEKKNSCSICSESF--HTVEELYSHMDSHQQPESCNHSNSPS 345
+ + +H+GEK C C ++F H L+ + + P + + PS
Sbjct: 769 V-QPQSIHTGEKPYECKECGKAFRLHLQLSLHQKLVQVRNPLNVRNVGQPS 818
Score = 37.4 bits (85), Expect = 0.095
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 6/107 (5%)
Query: 1198 IKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFK 1257
I +++ Y E H A+ + + +ECK C + F + L H H+ E +K
Sbjct: 139 INQKIISYEEMPAYTH-ASPIHNTHKPYECKECGKYFSCGSNLIQHQSIHTGE---KPYK 194
Query: 1258 CPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C C F +L +H G +K ++C +C + F T+L H
Sbjct: 195 CKECGKAFQLHIQLTRHQKFHTG--EKTFECKECGKAFNLPTQLNRH 239
>gi|156547246 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 191 bits (484), Expect = 5e-48
Identities = 171/670 (25%), Positives = 258/670 (38%), Gaps = 130/670 (19%)
Query: 115 GLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 174
G PY C C K+F++ S L H + HS + P+KC+ C + F + + H +HTG+K Y
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPY 313
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------E 225
C EC F + +L H + HT KPYKC C + F S+L H +H E
Sbjct: 314 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNE 373
Query: 226 RNKDGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQ 282
K +Q+ + W++ + KC++C + F L H H P +
Sbjct: 374 CGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIH-QTIHTGEKP------YK 426
Query: 283 CVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNH 340
C C ++F + L H +VH+GEK C+ C ++F L +H H +P CN
Sbjct: 427 CNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNE 485
Query: 341 SNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQ 400
+ T +S L+ + + P + K + ++ T +
Sbjct: 486 CS------------KVFTQNSQLA-NHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHS 532
Query: 401 AKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVH 460
+ Y CI C K F+ + L+ H +KP + C C +V L H + VH
Sbjct: 533 GEKPYKCIECGKS-FTQKSHLRSHRGIHSGEKP---YKCNECGKVFAQTSQLARHWR-VH 587
Query: 461 EAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYM 520
+ P Y+CN C +D ++L H G + C C
Sbjct: 588 TGEKP-----------YKCNDCGRAFSDRSSLTFHQAIHTG--------EKPYKCHECGK 628
Query: 521 GFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKH 580
F +S L H R++H T ++P Y C+ C + +S L +K
Sbjct: 629 VFRHNSYLATH-RRIH--------------TGEKP----YKCNECGKAFSMHSNLTTHK- 668
Query: 581 IKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCG 640
IH G+K Y CNQCG
Sbjct: 669 -------------VIHTGEK--------------------------------PYKCNQCG 683
Query: 641 AKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCD 700
+T H +TH T C +C K F + SL H IH Y C C
Sbjct: 684 KVFTQNSHLANHQRTH--TGEKPYRCNECGKAFSVRSSLTTHQAIH--TGKKPYKCNECG 739
Query: 701 KQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWD 760
K FT L H +RCT C + F + S+ H+A+ H+ EK+ Y+C C
Sbjct: 740 KVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAI-HTGEKR-YKCNECGKV 797
Query: 761 FRNETDLQLH 770
FR ++L H
Sbjct: 798 FRQSSNLASH 807
Score = 188 bits (477), Expect = 3e-47
Identities = 180/711 (25%), Positives = 266/711 (37%), Gaps = 149/711 (20%)
Query: 128 SRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSD 187
+ S L +++S P+KC C + F + H ++H+G+K Y CSEC F+
Sbjct: 239 NHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRS 298
Query: 188 HLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQK 247
+L IH HT KPYKC C + F +S L H ++H K K
Sbjct: 299 NLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEK----------------PYK 342
Query: 248 CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGE 307
C++C + F +L H H P +C C +LF + + L++H ++H+GE
Sbjct: 343 CNECGKAFRGHSNLTTH-QLIHTGEKP------FKCNECGKLFTQNSHLISHW-RIHTGE 394
Query: 308 KKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSV 365
K C+ C ++F L H H ++P CN Y S
Sbjct: 395 KPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGK----VFRYNSY----------- 439
Query: 366 DSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNK--QLFSSLAVLQ- 422
GR R TG + Y C C K + S+LA Q
Sbjct: 440 ---------------LGRHRRVH-----TG------EKPYKCNECGKAFSMHSNLATHQV 473
Query: 423 IHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFC 482
IH T KP + C C +V L H +++H + P Y+CN C
Sbjct: 474 IHTGT----KPFK---CNECSKVFTQNSQLANH-RRIHTGEKP-----------YKCNEC 514
Query: 483 SEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGS 542
+ + ++L H + H P + C C F S L H R +H SG
Sbjct: 515 GKAFSVRSSLTTH-QAIHSGEKP-------YKCIECGKSFTQKSHLRSH-RGIH---SGE 562
Query: 543 RFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSR 602
+ Y C+ C +F +L +H + +H G+K
Sbjct: 563 K---------------PYKCNEC--GKVFAQTSQLARHWR------------VHTGEKPY 593
Query: 603 ALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTV 660
+ +++SL QA+ TGE Y C++CG + TH + H T
Sbjct: 594 KCNDCGRAFSDRSSLTFHQAI------HTGEKPYKCHECGKVFRHNSYLATHRRIH--TG 645
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C +C K F +L H IH Y C C K FT L H
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHKVIH--TGEKPYKCNQCGKVFTQNSHLANHQRTHTGEK 703
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
+RC C + F + S+ H A+ H+ KK Y+C C F L H +
Sbjct: 704 PYRCNECGKAFSVRSSLTTHQAI-HTG-KKPYKCNECGKVFTQNAHL---ANHRRIHTGE 758
Query: 781 KVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLR 829
K ++C CG++F L H+ H+ K+Y C C K F L H R
Sbjct: 759 KPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHR 809
Score = 157 bits (398), Expect = 5e-38
Identities = 154/645 (23%), Positives = 231/645 (35%), Gaps = 173/645 (26%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F S++T H++ + + P +++ SH
Sbjct: 338 EKPYKCNECGKAFRGHSNLTTHQL--------IHTGEKPFKCNECGKLFTQNSHLISHWR 389
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C C K+FS S L H+ H+ + P+KC C ++F++ R
Sbjct: 390 -IHTGEK------PYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGR 442
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H ++HTG+K Y C+EC AFS +L H HT KP+KC C + F +S L H ++
Sbjct: 443 HRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRI 502
Query: 224 HERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQC 283
H K KC++C + F L H A H P +C
Sbjct: 503 HTGEK----------------PYKCNECGKAFSVRSSLTTHQA-IHSGEKP------YKC 539
Query: 284 VYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHS 341
+ C + F +++ L +H +HSGEK C+ C + F +L H H ++P CN
Sbjct: 540 IECGKSFTQKSHLRSH-RGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDC 598
Query: 342 NSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQA 401
++ SS T + G K
Sbjct: 599 GR------AFSDRSSLTFHQAIHT----------------GEK----------------- 619
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
Y C C K +F + L H + +KP + C C + NL H K +H
Sbjct: 620 --PYKCHECGK-VFRHNSYLATHRRIHTGEKP---YKCNECGKAFSMHSNLTTH-KVIHT 672
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+CN C +V + L H R G + C C
Sbjct: 673 GEKP-----------YKCNQCGKVFTQNSHLANHQRTHTG--------EKPYRCNECGKA 713
Query: 522 FLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
F SSL H + +H T K+P Y C+ C V N H+
Sbjct: 714 FSVRSSLTTH-QAIH--------------TGKKP----YKCNEC------GKVFTQNAHL 748
Query: 582 KENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGA 641
NH+ IH G+K Y C +CG
Sbjct: 749 -ANHRR-------IHTGEK--------------------------------PYRCTECGK 768
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIH 686
+ S TH+ H T + C +C K F +L H +H
Sbjct: 769 AFRVRSSLTTHMAIH--TGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 155 bits (393), Expect = 2e-37
Identities = 157/631 (24%), Positives = 226/631 (35%), Gaps = 110/631 (17%)
Query: 477 YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH 536
Y+CN C + + L H R G + C C F S+L H
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSG--------EKPYKCSECGKTFTVRSNLTIH----- 303
Query: 537 CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIK-------------- 582
V+ T ++P Y C C NS L ++ I
Sbjct: 304 ----------QVIHTGEKP----YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA 349
Query: 583 -ENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQC 639
H N+ IH G+K + + + + L + TGE Y CN+C
Sbjct: 350 FRGHSNL-TTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRI------HTGEKPYKCNEC 402
Query: 640 GAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESC 699
G ++ S H H T C +C K F L +H +H Y C C
Sbjct: 403 GKAFSVRSSLAIHQTIH--TGEKPYKCNECGKVFRYNSYLGRHRRVH--TGEKPYKCNEC 458
Query: 700 DKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCN 758
K F+ +L H + +HT F+C C +VF + H + H+ EK Y+C C
Sbjct: 459 GKAFSMHSNLATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRI-HTGEKP-YKCNECG 515
Query: 759 WDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSK 816
F + L H + + K +KCI CG+SF + L+ H HS K Y C C K
Sbjct: 516 KAFSVRSSL---TTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGK 572
Query: 817 AFHAIILLEKHLREKHCVFETKTPNCGTNGAS-------EQVQKEEVELQTLLTNSQESH 869
F L +H R K +CG + + + E + H
Sbjct: 573 VFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRH 632
Query: 870 NSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGN 929
NS+ + + T E Y C+ CG A++M + L H++ I GE
Sbjct: 633 NSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKV----IHTGEKP------------ 676
Query: 930 YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN 989
YKCN C + F + L H +TH G K Y C CG+ F +LT H+ H+
Sbjct: 677 YKCNQCGKVFTQNSHLANHQRTHTGE-KPYRCNECGKAFSVRSSLTTHQAIHT-GKKPYK 734
Query: 990 CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNG 1049
C C H ++H + +RC C + L H H TG
Sbjct: 735 CNECGKVFTQNAHLANHRRIHTGEK----PYRCTECGKAFRVRSSLTTHMAIH---TG-- 785
Query: 1050 SAVQTTGRGQHVQKLYKCASCLKEFRSKQDL 1080
+K YKC C K FR +L
Sbjct: 786 ------------EKRYKCNECGKVFRQSSNL 804
Score = 147 bits (370), Expect = 9e-35
Identities = 162/661 (24%), Positives = 229/661 (34%), Gaps = 130/661 (19%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y CN+CG +T + +H + H K C +C K F + +L H IH
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSGEKPYK--CSECGKTFTVRSNLTIHQVIH--TGEKP 312
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y C C K F L H ++C C + F ++ H + H+ EK ++
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLI-HTGEKP-FK 370
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNC 811
C C F + L + H + K +KC CG++F L H T H+ K Y C
Sbjct: 371 CNECGKLFTQNSHL---ISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKC 427
Query: 812 KFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNS 871
C K F L +H R K CG S +S
Sbjct: 428 NECGKVFRYNSYLGRHRRVHTGEKPYKCNECG---------------------KAFSMHS 466
Query: 872 HDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYK 931
+ + + + T + C+ C +T + L NH+ I GE YK
Sbjct: 467 NLATHQVIHTGTKPFKCNECSKVFTQNSQLANHR----RIHTGEKP------------YK 510
Query: 932 CNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCR 991
CN C + F + L H H G K Y C CG+ F L H+ HS C
Sbjct: 511 CNECGKAFSVRSSLTTHQAIHSGE-KPYKCIECGKSFTQKSHLRSHRGIHSGE-KPYKCN 568
Query: 992 ICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSA 1051
C + H ++H + ++C C + + L H H TG
Sbjct: 569 ECGKVFAQTSQLARHWRVHTGEK----PYKCNDCGRAFSDRSSLTFHQAIH---TG---- 617
Query: 1052 VQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGIN 1108
+K YKC C K FR L ++ PY C K+ S N
Sbjct: 618 ----------EKPYKCHECGKVFRHNSYLATHRRIHTGEKPY----KCNECGKAFSMHSN 663
Query: 1109 V-----------PPGTNRPG--LGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQN 1155
+ P N+ G QN +L A + G RC+ C F S L
Sbjct: 664 LTTHKVIHTGEKPYKCNQCGKVFTQNSHL-ANHQRTHTGEKPYRCNECGKAFSVRSSLTT 722
Query: 1156 HIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVA 1215
H Q IH KK Y+C +C VF H+A
Sbjct: 723 H-QAIH----------------------------TGKKPYKCNECGKVFTQ----NAHLA 749
Query: 1216 NH-MIDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQ 1273
NH I G + C C + F + L H+ H+ E +KC C VF Q++ L
Sbjct: 750 NHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGE---KRYKCNECGKVFRQSSNLAS 806
Query: 1274 H 1274
H
Sbjct: 807 H 807
Score = 145 bits (367), Expect = 2e-34
Identities = 154/644 (23%), Positives = 221/644 (34%), Gaps = 128/644 (19%)
Query: 666 CPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCT 725
C +C K F +L H IH Y C C K FT +L H + ++C
Sbjct: 259 CNECGKAFTQNSNLTSHRRIHS--GEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCH 316
Query: 726 LCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKC 785
C +VF + H + H+ EK Y+C C FR ++L H + K KC
Sbjct: 317 ECGKVFRHNSYLATHRRI-HTGEKP-YKCNECGKAFRGHSNL---TTHQLIHTGEKPFKC 371
Query: 786 IFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG 843
CG+ F L H I T K Y C C KAF L H K CG
Sbjct: 372 NECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG 431
Query: 844 TNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQN 903
+NS+ G V T E Y C+ CG A++M + L
Sbjct: 432 ---------------------KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLAT 470
Query: 904 HQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPI 963
HQ+ +P +KCN CS+ F + L H + H G K Y C
Sbjct: 471 HQVIHTGTKP----------------FKCNECSKVFTQNSQLANHRRIHTGE-KPYKCNE 513
Query: 964 CGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCV 1023
CG+ F +LT H+ HS C C + H + H + + ++C
Sbjct: 514 CGKAFSVRSSLTTHQAIHSGEKPY-KCIECGKSFTQKS----HLRSHRGIHSGEKPYKCN 568
Query: 1024 VCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV-- 1081
C + T +L H H TG +K YKC C + F + L
Sbjct: 569 ECGKVFAQTSQLARHWRVH------------TG-----EKPYKCNDCGRAFSDRSSLTFH 611
Query: 1082 -KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRC 1140
+ PY C C + + + + A + G +C
Sbjct: 612 QAIHTGEKPYK-CHECGKVFR-------------------HNSYLATHRRIHTGEKPYKC 651
Query: 1141 SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC 1200
+ C F S L H + IH +K Y+C +C
Sbjct: 652 NECGKAFSMHSNLTTH-KVIHTG----------------------------EKPYKCNQC 682
Query: 1201 QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV 1260
VF + H H ++ + C C + F + L H H+ + +KC
Sbjct: 683 GKVFTQNSHLANHQRTHTGEKP--YRCNECGKAFSVRSSLTTHQAIHTGKK---PYKCNE 737
Query: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C VF Q L H G+ K Y CT+C + F ++ L H
Sbjct: 738 CGKVFTQNAHLANHRRIHTGE--KPYRCTECGKAFRVRSSLTTH 779
Score = 139 bits (351), Expect = 1e-32
Identities = 168/732 (22%), Positives = 247/732 (33%), Gaps = 164/732 (22%)
Query: 287 HELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSP 344
HEL SL+ + +S K C+ C ++F L SH H ++P C+
Sbjct: 236 HEL--NHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGK- 292
Query: 345 SLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVT 404
+ T SNL++ P
Sbjct: 293 -----------TFTVRSNLTIHQVIHTGEKP----------------------------- 312
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C C K +F + L H + +KP + C C + NL H + +H +
Sbjct: 313 YKCHECGK-VFRHNSYLATHRRIHTGEKPYK---CNECGKAFRGHSNLTTH-QLIHTGEK 367
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLT 524
P ++CN C ++ + L H R G + C C F
Sbjct: 368 P-----------FKCNECGKLFTQNSHLISHWRIHTG--------EKPYKCNECGKAFSV 408
Query: 525 DSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKEN 584
SSL H + +H T ++P Y C+ C V + N ++ +
Sbjct: 409 RSSLAIH-QTIH--------------TGEKP----YKCNEC------GKVFRYNSYLGRH 443
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYT 644
+ +H G+K + ++L Q + T + CN+C +T
Sbjct: 444 RR--------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTG----TKPFKCNECSKVFT 491
Query: 645 SLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFT 704
H + H T C +C K F + SL H IH Y C C K FT
Sbjct: 492 QNSQLANHRRIH--TGEKPYKCNECGKAFSVRSSLTTHQAIH--SGEKPYKCIECGKSFT 547
Query: 705 SVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNE 764
L+ H ++C C +VF + H V H+ EK Y+C C F +
Sbjct: 548 QKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRV-HTGEKP-YKCNDCGRAFSDR 605
Query: 765 TDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF--HA 820
+ L H + K +KC CG+ F L H I T K Y C C KAF H+
Sbjct: 606 SSLTF---HQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHS 662
Query: 821 IILLEK--HLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
+ K H EK K CG + NSH + +
Sbjct: 663 NLTTHKVIHTGEK----PYKCNQCG---------------------KVFTQNSHLANHQR 697
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRT 938
T E Y C+ CG A+++ + L HQ +P YKCN C +
Sbjct: 698 THTGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKP----------------YKCNECGKV 741
Query: 939 FFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQ 998
F L H + H G K Y C CG+ F +LT H H+ C C +
Sbjct: 742 FTQNAHLANHRRIHTGE-KPYRCTECGKAFRVRSSLTTHMAIHTGE-KRYKCNECGKVFR 799
Query: 999 SEEEFLEHCQMH 1010
H +MH
Sbjct: 800 QSSNLASHHRMH 811
Score = 137 bits (344), Expect = 9e-32
Identities = 108/399 (27%), Positives = 158/399 (39%), Gaps = 51/399 (12%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS S L H+ H+ PFKC CS++F H ++HTG+K Y C
Sbjct: 452 PYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKC 511
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERN 227
+EC AFS L H H+ KPYKC C + F S L H +H E
Sbjct: 512 NECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECG 571
Query: 228 KDGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
K +Q+ W++ +K C+ C F L H A H P +C
Sbjct: 572 KVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQA-IHTGEKP------YKCH 624
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN 342
C ++F + L H ++H+GEK C+ C ++F L +H H ++P CN
Sbjct: 625 ECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCG 683
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
T +S+L+ T P G+ + + + T + K
Sbjct: 684 KVF------------TQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT-THQAIHTGK 730
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K +F+ A L H + +KP + C V SL H+ +H
Sbjct: 731 KPYKCNECGK-VFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSL---TTHMA-IHTG 785
Query: 463 QDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHG 501
+ Y+CN C +V + L H R G
Sbjct: 786 EKR-----------YKCNECGKVFRQSSNLASHHRMHTG 813
Score = 109 bits (272), Expect = 2e-23
Identities = 60/192 (31%), Positives = 90/192 (46%), Gaps = 24/192 (12%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS S L H+ H+ + P+KC C ++F H + HTG+K Y C
Sbjct: 648 PYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRC 707
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+EC AFS L H HT KPYKC C + F ++ L H ++H K
Sbjct: 708 NECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEK-------- 759
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+C++C + F L H+A E R +C C ++F + ++L
Sbjct: 760 --------PYRCTECGKAFRVRSSLTTHMA-----IHTGEKR--YKCNECGKVFRQSSNL 804
Query: 297 MNHMEQVHSGEK 308
+H ++H+GEK
Sbjct: 805 ASH-HRMHTGEK 815
Score = 105 bits (263), Expect = 2e-22
Identities = 130/541 (24%), Positives = 185/541 (34%), Gaps = 109/541 (20%)
Query: 780 GKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAF--------HAIILLEKHLR 829
GK +KC CG++F L H HS K Y C C K F H +I H
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVI----HTG 309
Query: 830 EKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCD 889
EK K CG HNS+ + + T E Y C+
Sbjct: 310 EK----PYKCHECG---------------------KVFRHNSYLATHRRIHTGEKPYKCN 344
Query: 890 ICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHM 949
CG A+ + L HQL I GE +KCN C + F + L H
Sbjct: 345 ECGKAFRGHSNLTTHQL----IHTGEKP------------FKCNECGKLFTQNSHLISHW 388
Query: 950 QTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQM 1009
+ H G K Y C CG+ F +L H+ H+ C C + H ++
Sbjct: 389 RIHTGE-KPYKCNECGKAFSVRSSLAIHQTIHTGEKPY-KCNECGKVFRYNSYLGRHRRV 446
Query: 1010 HPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCAS 1069
H + ++C C + + L H H TG K +KC
Sbjct: 447 HTGEKP----YKCNECGKAFSMHSNLATHQVIH---TGT--------------KPFKCNE 485
Query: 1070 CLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSA 1126
C K F L ++ PY C K+ S R L ++ + +
Sbjct: 486 CSKVFTQNSQLANHRRIHTGEKPYK----CNECGKAFSV---------RSSLTTHQAIHS 532
Query: 1127 IEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISP 1186
G +C C F +S L++H E N Q S + R
Sbjct: 533 -------GEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWR 585
Query: 1187 SQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIE 1246
+ EK Y+C C F + + H A H ++ ++C C + F + L H
Sbjct: 586 VHTGEKP-YKCNDCGRAFSDRSSLTFHQAIHTGEKP--YKCHECGKVFRHNSYLATHRRI 642
Query: 1247 HSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTM 1306
H+ E +KC C F + L H G+ K Y C QC + F + L NH
Sbjct: 643 HTGEK---PYKCNECGKAFSMHSNLTTHKVIHTGE--KPYKCNQCGKVFTQNSHLANHQR 697
Query: 1307 T 1307
T
Sbjct: 698 T 698
Score = 91.3 bits (225), Expect = 6e-18
Identities = 116/513 (22%), Positives = 192/513 (37%), Gaps = 69/513 (13%)
Query: 825 EKHLREKHCVFETKTPN------CGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
+K++ + C + T N G +Q + ++E + + S +SH +
Sbjct: 135 QKNVHDFECQWRDDTGNYKGVLMAQKEGKRDQRDRRDIENKLMNNQLGVSFHSHLPELQL 194
Query: 879 VDTSEPMYGCDIC------GAAYT----METLLQNHQLRD-HNIRPGESAIVKKKAELIK 927
MY C+ G++ + + + +Q H+ + H + ++KA
Sbjct: 195 FQGEGKMYECNQVEKSTNNGSSVSPLQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCG 254
Query: 928 GNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDT 987
YKCN C + F + L H + H G K Y C CG+ F LT H+V H+
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGE-KPYKCSECGKTFTVRSNLTIHQVIHTGE-KP 312
Query: 988 GNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTG 1047
C C + H ++H + ++C C + L H H TG
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEK----PYKCNECGKAFRGHSNLTTHQLIH---TG 365
Query: 1048 NGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVN-LSKSA 1103
+K +KC C K F L+ ++ PY C C S +
Sbjct: 366 --------------EKPFKCNECGKLFTQNSHLISHWRIHTGEKPY-KCNECGKAFSVRS 410
Query: 1104 SPGINVPPGTNRPGLGQNE-----NLSAIEGKGK---VGGLKTRCSSCNVKFESESELQN 1155
S I+ T NE ++ G+ + G +C+ C F S L
Sbjct: 411 SLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLAT 470
Query: 1156 HIQTIHRELVP----DSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQ 1211
H Q IH P + + + Q++ RI + K Y+C +C F +
Sbjct: 471 H-QVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGE----KPYKCNECGKAFSVRSSLT 525
Query: 1212 VHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1271
H A H ++ ++C C ++F + L+ H HS E +KC C VF Q ++L
Sbjct: 526 THQAIHSGEK--PYKCIECGKSFTQKSHLRSHRGIHSGE---KPYKCNECGKVFAQTSQL 580
Query: 1272 QQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+H + H E K Y C C + F ++ L H
Sbjct: 581 ARH-WRVHTGE-KPYKCNDCGRAFSDRSSLTFH 611
Score = 88.2 bits (217), Expect = 5e-17
Identities = 34/87 (39%), Positives = 55/87 (63%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K F++ ++L +H + H+ + P++CT C + F+ + S H+ +HTG+K+Y C
Sbjct: 732 PYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKC 791
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYK 203
+EC F +S +L H + HT KPYK
Sbjct: 792 NECGKVFRQSSNLASHHRMHTGEKPYK 818
>gi|38788302 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 191 bits (484), Expect = 5e-48
Identities = 171/670 (25%), Positives = 258/670 (38%), Gaps = 130/670 (19%)
Query: 115 GLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 174
G PY C C K+F++ S L H + HS + P+KC+ C + F + + H +HTG+K Y
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPY 313
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------E 225
C EC F + +L H + HT KPYKC C + F S+L H +H E
Sbjct: 314 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNE 373
Query: 226 RNKDGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQ 282
K +Q+ + W++ + KC++C + F L H H P +
Sbjct: 374 CGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIH-QTIHTGEKP------YK 426
Query: 283 CVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNH 340
C C ++F + L H +VH+GEK C+ C ++F L +H H +P CN
Sbjct: 427 CNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNE 485
Query: 341 SNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQ 400
+ T +S L+ + + P + K + ++ T +
Sbjct: 486 CS------------KVFTQNSQLA-NHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHS 532
Query: 401 AKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVH 460
+ Y CI C K F+ + L+ H +KP + C C +V L H + VH
Sbjct: 533 GEKPYKCIECGKS-FTQKSHLRSHRGIHSGEKP---YKCNECGKVFAQTSQLARHWR-VH 587
Query: 461 EAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYM 520
+ P Y+CN C +D ++L H G + C C
Sbjct: 588 TGEKP-----------YKCNDCGRAFSDRSSLTFHQAIHTG--------EKPYKCHECGK 628
Query: 521 GFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKH 580
F +S L H R++H T ++P Y C+ C + +S L +K
Sbjct: 629 VFRHNSYLATH-RRIH--------------TGEKP----YKCNECGKAFSMHSNLTTHK- 668
Query: 581 IKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCG 640
IH G+K Y CNQCG
Sbjct: 669 -------------VIHTGEK--------------------------------PYKCNQCG 683
Query: 641 AKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCD 700
+T H +TH T C +C K F + SL H IH Y C C
Sbjct: 684 KVFTQNSHLANHQRTH--TGEKPYRCNECGKAFSVRSSLTTHQAIH--TGKKPYKCNECG 739
Query: 701 KQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWD 760
K FT L H +RCT C + F + S+ H+A+ H+ EK+ Y+C C
Sbjct: 740 KVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAI-HTGEKR-YKCNECGKV 797
Query: 761 FRNETDLQLH 770
FR ++L H
Sbjct: 798 FRQSSNLASH 807
Score = 188 bits (477), Expect = 3e-47
Identities = 180/711 (25%), Positives = 266/711 (37%), Gaps = 149/711 (20%)
Query: 128 SRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSD 187
+ S L +++S P+KC C + F + H ++H+G+K Y CSEC F+
Sbjct: 239 NHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRS 298
Query: 188 HLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQK 247
+L IH HT KPYKC C + F +S L H ++H K K
Sbjct: 299 NLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEK----------------PYK 342
Query: 248 CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGE 307
C++C + F +L H H P +C C +LF + + L++H ++H+GE
Sbjct: 343 CNECGKAFRGHSNLTTH-QLIHTGEKP------FKCNECGKLFTQNSHLISHW-RIHTGE 394
Query: 308 KKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSV 365
K C+ C ++F L H H ++P CN Y S
Sbjct: 395 KPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGK----VFRYNSY----------- 439
Query: 366 DSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNK--QLFSSLAVLQ- 422
GR R TG + Y C C K + S+LA Q
Sbjct: 440 ---------------LGRHRRVH-----TG------EKPYKCNECGKAFSMHSNLATHQV 473
Query: 423 IHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFC 482
IH T KP + C C +V L H +++H + P Y+CN C
Sbjct: 474 IHTGT----KPFK---CNECSKVFTQNSQLANH-RRIHTGEKP-----------YKCNEC 514
Query: 483 SEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGS 542
+ + ++L H + H P + C C F S L H R +H SG
Sbjct: 515 GKAFSVRSSLTTH-QAIHSGEKP-------YKCIECGKSFTQKSHLRSH-RGIH---SGE 562
Query: 543 RFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSR 602
+ Y C+ C +F +L +H + +H G+K
Sbjct: 563 K---------------PYKCNEC--GKVFAQTSQLARHWR------------VHTGEKPY 593
Query: 603 ALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTV 660
+ +++SL QA+ TGE Y C++CG + TH + H T
Sbjct: 594 KCNDCGRAFSDRSSLTFHQAI------HTGEKPYKCHECGKVFRHNSYLATHRRIH--TG 645
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C +C K F +L H IH Y C C K FT L H
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHKVIH--TGEKPYKCNQCGKVFTQNSHLANHQRTHTGEK 703
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
+RC C + F + S+ H A+ H+ KK Y+C C F L H +
Sbjct: 704 PYRCNECGKAFSVRSSLTTHQAI-HTG-KKPYKCNECGKVFTQNAHL---ANHRRIHTGE 758
Query: 781 KVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLR 829
K ++C CG++F L H+ H+ K+Y C C K F L H R
Sbjct: 759 KPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHR 809
Score = 157 bits (398), Expect = 5e-38
Identities = 154/645 (23%), Positives = 231/645 (35%), Gaps = 173/645 (26%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F S++T H++ + + P +++ SH
Sbjct: 338 EKPYKCNECGKAFRGHSNLTTHQL--------IHTGEKPFKCNECGKLFTQNSHLISHWR 389
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C C K+FS S L H+ H+ + P+KC C ++F++ R
Sbjct: 390 -IHTGEK------PYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGR 442
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H ++HTG+K Y C+EC AFS +L H HT KP+KC C + F +S L H ++
Sbjct: 443 HRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRI 502
Query: 224 HERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQC 283
H K KC++C + F L H A H P +C
Sbjct: 503 HTGEK----------------PYKCNECGKAFSVRSSLTTHQA-IHSGEKP------YKC 539
Query: 284 VYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHS 341
+ C + F +++ L +H +HSGEK C+ C + F +L H H ++P CN
Sbjct: 540 IECGKSFTQKSHLRSH-RGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDC 598
Query: 342 NSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQA 401
++ SS T + G K
Sbjct: 599 GR------AFSDRSSLTFHQAIHT----------------GEK----------------- 619
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
Y C C K +F + L H + +KP + C C + NL H K +H
Sbjct: 620 --PYKCHECGK-VFRHNSYLATHRRIHTGEKP---YKCNECGKAFSMHSNLTTH-KVIHT 672
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+CN C +V + L H R G + C C
Sbjct: 673 GEKP-----------YKCNQCGKVFTQNSHLANHQRTHTG--------EKPYRCNECGKA 713
Query: 522 FLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
F SSL H + +H T K+P Y C+ C V N H+
Sbjct: 714 FSVRSSLTTH-QAIH--------------TGKKP----YKCNEC------GKVFTQNAHL 748
Query: 582 KENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGA 641
NH+ IH G+K Y C +CG
Sbjct: 749 -ANHRR-------IHTGEK--------------------------------PYRCTECGK 768
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIH 686
+ S TH+ H T + C +C K F +L H +H
Sbjct: 769 AFRVRSSLTTHMAIH--TGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 155 bits (393), Expect = 2e-37
Identities = 157/631 (24%), Positives = 226/631 (35%), Gaps = 110/631 (17%)
Query: 477 YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH 536
Y+CN C + + L H R G + C C F S+L H
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSG--------EKPYKCSECGKTFTVRSNLTIH----- 303
Query: 537 CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIK-------------- 582
V+ T ++P Y C C NS L ++ I
Sbjct: 304 ----------QVIHTGEKP----YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA 349
Query: 583 -ENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQC 639
H N+ IH G+K + + + + L + TGE Y CN+C
Sbjct: 350 FRGHSNL-TTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRI------HTGEKPYKCNEC 402
Query: 640 GAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESC 699
G ++ S H H T C +C K F L +H +H Y C C
Sbjct: 403 GKAFSVRSSLAIHQTIH--TGEKPYKCNECGKVFRYNSYLGRHRRVH--TGEKPYKCNEC 458
Query: 700 DKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCN 758
K F+ +L H + +HT F+C C +VF + H + H+ EK Y+C C
Sbjct: 459 GKAFSMHSNLATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRI-HTGEKP-YKCNECG 515
Query: 759 WDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSK 816
F + L H + + K +KCI CG+SF + L+ H HS K Y C C K
Sbjct: 516 KAFSVRSSL---TTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGK 572
Query: 817 AFHAIILLEKHLREKHCVFETKTPNCGTNGAS-------EQVQKEEVELQTLLTNSQESH 869
F L +H R K +CG + + + E + H
Sbjct: 573 VFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRH 632
Query: 870 NSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGN 929
NS+ + + T E Y C+ CG A++M + L H++ I GE
Sbjct: 633 NSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKV----IHTGEKP------------ 676
Query: 930 YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN 989
YKCN C + F + L H +TH G K Y C CG+ F +LT H+ H+
Sbjct: 677 YKCNQCGKVFTQNSHLANHQRTHTGE-KPYRCNECGKAFSVRSSLTTHQAIHT-GKKPYK 734
Query: 990 CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNG 1049
C C H ++H + +RC C + L H H TG
Sbjct: 735 CNECGKVFTQNAHLANHRRIHTGEK----PYRCTECGKAFRVRSSLTTHMAIH---TG-- 785
Query: 1050 SAVQTTGRGQHVQKLYKCASCLKEFRSKQDL 1080
+K YKC C K FR +L
Sbjct: 786 ------------EKRYKCNECGKVFRQSSNL 804
Score = 147 bits (370), Expect = 9e-35
Identities = 162/661 (24%), Positives = 229/661 (34%), Gaps = 130/661 (19%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y CN+CG +T + +H + H K C +C K F + +L H IH
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSGEKPYK--CSECGKTFTVRSNLTIHQVIH--TGEKP 312
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y C C K F L H ++C C + F ++ H + H+ EK ++
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLI-HTGEKP-FK 370
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNC 811
C C F + L + H + K +KC CG++F L H T H+ K Y C
Sbjct: 371 CNECGKLFTQNSHL---ISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKC 427
Query: 812 KFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNS 871
C K F L +H R K CG S +S
Sbjct: 428 NECGKVFRYNSYLGRHRRVHTGEKPYKCNECG---------------------KAFSMHS 466
Query: 872 HDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYK 931
+ + + + T + C+ C +T + L NH+ I GE YK
Sbjct: 467 NLATHQVIHTGTKPFKCNECSKVFTQNSQLANHR----RIHTGEKP------------YK 510
Query: 932 CNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCR 991
CN C + F + L H H G K Y C CG+ F L H+ HS C
Sbjct: 511 CNECGKAFSVRSSLTTHQAIHSGE-KPYKCIECGKSFTQKSHLRSHRGIHSGE-KPYKCN 568
Query: 992 ICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSA 1051
C + H ++H + ++C C + + L H H TG
Sbjct: 569 ECGKVFAQTSQLARHWRVHTGEK----PYKCNDCGRAFSDRSSLTFHQAIH---TG---- 617
Query: 1052 VQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGIN 1108
+K YKC C K FR L ++ PY C K+ S N
Sbjct: 618 ----------EKPYKCHECGKVFRHNSYLATHRRIHTGEKPY----KCNECGKAFSMHSN 663
Query: 1109 V-----------PPGTNRPG--LGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQN 1155
+ P N+ G QN +L A + G RC+ C F S L
Sbjct: 664 LTTHKVIHTGEKPYKCNQCGKVFTQNSHL-ANHQRTHTGEKPYRCNECGKAFSVRSSLTT 722
Query: 1156 HIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVA 1215
H Q IH KK Y+C +C VF H+A
Sbjct: 723 H-QAIH----------------------------TGKKPYKCNECGKVFTQ----NAHLA 749
Query: 1216 NH-MIDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQ 1273
NH I G + C C + F + L H+ H+ E +KC C VF Q++ L
Sbjct: 750 NHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGE---KRYKCNECGKVFRQSSNLAS 806
Query: 1274 H 1274
H
Sbjct: 807 H 807
Score = 145 bits (367), Expect = 2e-34
Identities = 154/644 (23%), Positives = 221/644 (34%), Gaps = 128/644 (19%)
Query: 666 CPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCT 725
C +C K F +L H IH Y C C K FT +L H + ++C
Sbjct: 259 CNECGKAFTQNSNLTSHRRIHS--GEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCH 316
Query: 726 LCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKC 785
C +VF + H + H+ EK Y+C C FR ++L H + K KC
Sbjct: 317 ECGKVFRHNSYLATHRRI-HTGEKP-YKCNECGKAFRGHSNL---TTHQLIHTGEKPFKC 371
Query: 786 IFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG 843
CG+ F L H I T K Y C C KAF L H K CG
Sbjct: 372 NECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG 431
Query: 844 TNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQN 903
+NS+ G V T E Y C+ CG A++M + L
Sbjct: 432 ---------------------KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLAT 470
Query: 904 HQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPI 963
HQ+ +P +KCN CS+ F + L H + H G K Y C
Sbjct: 471 HQVIHTGTKP----------------FKCNECSKVFTQNSQLANHRRIHTGE-KPYKCNE 513
Query: 964 CGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCV 1023
CG+ F +LT H+ HS C C + H + H + + ++C
Sbjct: 514 CGKAFSVRSSLTTHQAIHSGEKPY-KCIECGKSFTQKS----HLRSHRGIHSGEKPYKCN 568
Query: 1024 VCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV-- 1081
C + T +L H H TG +K YKC C + F + L
Sbjct: 569 ECGKVFAQTSQLARHWRVH------------TG-----EKPYKCNDCGRAFSDRSSLTFH 611
Query: 1082 -KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRC 1140
+ PY C C + + + + A + G +C
Sbjct: 612 QAIHTGEKPYK-CHECGKVFR-------------------HNSYLATHRRIHTGEKPYKC 651
Query: 1141 SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC 1200
+ C F S L H + IH +K Y+C +C
Sbjct: 652 NECGKAFSMHSNLTTH-KVIHTG----------------------------EKPYKCNQC 682
Query: 1201 QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV 1260
VF + H H ++ + C C + F + L H H+ + +KC
Sbjct: 683 GKVFTQNSHLANHQRTHTGEKP--YRCNECGKAFSVRSSLTTHQAIHTGKK---PYKCNE 737
Query: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C VF Q L H G+ K Y CT+C + F ++ L H
Sbjct: 738 CGKVFTQNAHLANHRRIHTGE--KPYRCTECGKAFRVRSSLTTH 779
Score = 139 bits (351), Expect = 1e-32
Identities = 168/732 (22%), Positives = 247/732 (33%), Gaps = 164/732 (22%)
Query: 287 HELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSP 344
HEL SL+ + +S K C+ C ++F L SH H ++P C+
Sbjct: 236 HEL--NHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGK- 292
Query: 345 SLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVT 404
+ T SNL++ P
Sbjct: 293 -----------TFTVRSNLTIHQVIHTGEKP----------------------------- 312
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C C K +F + L H + +KP + C C + NL H + +H +
Sbjct: 313 YKCHECGK-VFRHNSYLATHRRIHTGEKPYK---CNECGKAFRGHSNLTTH-QLIHTGEK 367
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLT 524
P ++CN C ++ + L H R G + C C F
Sbjct: 368 P-----------FKCNECGKLFTQNSHLISHWRIHTG--------EKPYKCNECGKAFSV 408
Query: 525 DSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKEN 584
SSL H + +H T ++P Y C+ C V + N ++ +
Sbjct: 409 RSSLAIH-QTIH--------------TGEKP----YKCNEC------GKVFRYNSYLGRH 443
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYT 644
+ +H G+K + ++L Q + T + CN+C +T
Sbjct: 444 RR--------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTG----TKPFKCNECSKVFT 491
Query: 645 SLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFT 704
H + H T C +C K F + SL H IH Y C C K FT
Sbjct: 492 QNSQLANHRRIH--TGEKPYKCNECGKAFSVRSSLTTHQAIH--SGEKPYKCIECGKSFT 547
Query: 705 SVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNE 764
L+ H ++C C +VF + H V H+ EK Y+C C F +
Sbjct: 548 QKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRV-HTGEKP-YKCNDCGRAFSDR 605
Query: 765 TDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF--HA 820
+ L H + K +KC CG+ F L H I T K Y C C KAF H+
Sbjct: 606 SSLTF---HQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHS 662
Query: 821 IILLEK--HLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
+ K H EK K CG + NSH + +
Sbjct: 663 NLTTHKVIHTGEK----PYKCNQCG---------------------KVFTQNSHLANHQR 697
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRT 938
T E Y C+ CG A+++ + L HQ +P YKCN C +
Sbjct: 698 THTGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKP----------------YKCNECGKV 741
Query: 939 FFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQ 998
F L H + H G K Y C CG+ F +LT H H+ C C +
Sbjct: 742 FTQNAHLANHRRIHTGE-KPYRCTECGKAFRVRSSLTTHMAIHTGE-KRYKCNECGKVFR 799
Query: 999 SEEEFLEHCQMH 1010
H +MH
Sbjct: 800 QSSNLASHHRMH 811
Score = 137 bits (344), Expect = 9e-32
Identities = 108/399 (27%), Positives = 158/399 (39%), Gaps = 51/399 (12%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS S L H+ H+ PFKC CS++F H ++HTG+K Y C
Sbjct: 452 PYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKC 511
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERN 227
+EC AFS L H H+ KPYKC C + F S L H +H E
Sbjct: 512 NECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECG 571
Query: 228 KDGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
K +Q+ W++ +K C+ C F L H A H P +C
Sbjct: 572 KVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQA-IHTGEKP------YKCH 624
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN 342
C ++F + L H ++H+GEK C+ C ++F L +H H ++P CN
Sbjct: 625 ECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCG 683
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
T +S+L+ T P G+ + + + T + K
Sbjct: 684 KVF------------TQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT-THQAIHTGK 730
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K +F+ A L H + +KP + C V SL H+ +H
Sbjct: 731 KPYKCNECGK-VFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSL---TTHMA-IHTG 785
Query: 463 QDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHG 501
+ Y+CN C +V + L H R G
Sbjct: 786 EKR-----------YKCNECGKVFRQSSNLASHHRMHTG 813
Score = 109 bits (272), Expect = 2e-23
Identities = 60/192 (31%), Positives = 90/192 (46%), Gaps = 24/192 (12%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS S L H+ H+ + P+KC C ++F H + HTG+K Y C
Sbjct: 648 PYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRC 707
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+EC AFS L H HT KPYKC C + F ++ L H ++H K
Sbjct: 708 NECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEK-------- 759
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+C++C + F L H+A E R +C C ++F + ++L
Sbjct: 760 --------PYRCTECGKAFRVRSSLTTHMA-----IHTGEKR--YKCNECGKVFRQSSNL 804
Query: 297 MNHMEQVHSGEK 308
+H ++H+GEK
Sbjct: 805 ASH-HRMHTGEK 815
Score = 105 bits (263), Expect = 2e-22
Identities = 130/541 (24%), Positives = 185/541 (34%), Gaps = 109/541 (20%)
Query: 780 GKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAF--------HAIILLEKHLR 829
GK +KC CG++F L H HS K Y C C K F H +I H
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVI----HTG 309
Query: 830 EKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCD 889
EK K CG HNS+ + + T E Y C+
Sbjct: 310 EK----PYKCHECG---------------------KVFRHNSYLATHRRIHTGEKPYKCN 344
Query: 890 ICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHM 949
CG A+ + L HQL I GE +KCN C + F + L H
Sbjct: 345 ECGKAFRGHSNLTTHQL----IHTGEKP------------FKCNECGKLFTQNSHLISHW 388
Query: 950 QTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQM 1009
+ H G K Y C CG+ F +L H+ H+ C C + H ++
Sbjct: 389 RIHTGE-KPYKCNECGKAFSVRSSLAIHQTIHTGEKPY-KCNECGKVFRYNSYLGRHRRV 446
Query: 1010 HPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCAS 1069
H + ++C C + + L H H TG K +KC
Sbjct: 447 HTGEKP----YKCNECGKAFSMHSNLATHQVIH---TGT--------------KPFKCNE 485
Query: 1070 CLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSA 1126
C K F L ++ PY C K+ S R L ++ + +
Sbjct: 486 CSKVFTQNSQLANHRRIHTGEKPYK----CNECGKAFSV---------RSSLTTHQAIHS 532
Query: 1127 IEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISP 1186
G +C C F +S L++H E N Q S + R
Sbjct: 533 -------GEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWR 585
Query: 1187 SQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIE 1246
+ EK Y+C C F + + H A H ++ ++C C + F + L H
Sbjct: 586 VHTGEKP-YKCNDCGRAFSDRSSLTFHQAIHTGEKP--YKCHECGKVFRHNSYLATHRRI 642
Query: 1247 HSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTM 1306
H+ E +KC C F + L H G+ K Y C QC + F + L NH
Sbjct: 643 HTGEK---PYKCNECGKAFSMHSNLTTHKVIHTGE--KPYKCNQCGKVFTQNSHLANHQR 697
Query: 1307 T 1307
T
Sbjct: 698 T 698
Score = 91.3 bits (225), Expect = 6e-18
Identities = 116/513 (22%), Positives = 192/513 (37%), Gaps = 69/513 (13%)
Query: 825 EKHLREKHCVFETKTPN------CGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
+K++ + C + T N G +Q + ++E + + S +SH +
Sbjct: 135 QKNVHDFECQWRDDTGNYKGVLMAQKEGKRDQRDRRDIENKLMNNQLGVSFHSHLPELQL 194
Query: 879 VDTSEPMYGCDIC------GAAYT----METLLQNHQLRD-HNIRPGESAIVKKKAELIK 927
MY C+ G++ + + + +Q H+ + H + ++KA
Sbjct: 195 FQGEGKMYECNQVEKSTNNGSSVSPLQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCG 254
Query: 928 GNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDT 987
YKCN C + F + L H + H G K Y C CG+ F LT H+V H+
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGE-KPYKCSECGKTFTVRSNLTIHQVIHTGE-KP 312
Query: 988 GNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTG 1047
C C + H ++H + ++C C + L H H TG
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEK----PYKCNECGKAFRGHSNLTTHQLIH---TG 365
Query: 1048 NGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVN-LSKSA 1103
+K +KC C K F L+ ++ PY C C S +
Sbjct: 366 --------------EKPFKCNECGKLFTQNSHLISHWRIHTGEKPY-KCNECGKAFSVRS 410
Query: 1104 SPGINVPPGTNRPGLGQNE-----NLSAIEGKGK---VGGLKTRCSSCNVKFESESELQN 1155
S I+ T NE ++ G+ + G +C+ C F S L
Sbjct: 411 SLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLAT 470
Query: 1156 HIQTIHRELVP----DSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQ 1211
H Q IH P + + + Q++ RI + K Y+C +C F +
Sbjct: 471 H-QVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGE----KPYKCNECGKAFSVRSSLT 525
Query: 1212 VHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1271
H A H ++ ++C C ++F + L+ H HS E +KC C VF Q ++L
Sbjct: 526 THQAIHSGEK--PYKCIECGKSFTQKSHLRSHRGIHSGE---KPYKCNECGKVFAQTSQL 580
Query: 1272 QQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+H + H E K Y C C + F ++ L H
Sbjct: 581 ARH-WRVHTGE-KPYKCNDCGRAFSDRSSLTFH 611
Score = 88.2 bits (217), Expect = 5e-17
Identities = 34/87 (39%), Positives = 55/87 (63%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K F++ ++L +H + H+ + P++CT C + F+ + S H+ +HTG+K+Y C
Sbjct: 732 PYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKC 791
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYK 203
+EC F +S +L H + HT KPYK
Sbjct: 792 NECGKVFRQSSNLASHHRMHTGEKPYK 818
>gi|38788288 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 191 bits (484), Expect = 5e-48
Identities = 171/670 (25%), Positives = 258/670 (38%), Gaps = 130/670 (19%)
Query: 115 GLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 174
G PY C C K+F++ S L H + HS + P+KC+ C + F + + H +HTG+K Y
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPY 313
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------E 225
C EC F + +L H + HT KPYKC C + F S+L H +H E
Sbjct: 314 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNE 373
Query: 226 RNKDGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQ 282
K +Q+ + W++ + KC++C + F L H H P +
Sbjct: 374 CGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIH-QTIHTGEKP------YK 426
Query: 283 CVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNH 340
C C ++F + L H +VH+GEK C+ C ++F L +H H +P CN
Sbjct: 427 CNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNE 485
Query: 341 SNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQ 400
+ T +S L+ + + P + K + ++ T +
Sbjct: 486 CS------------KVFTQNSQLA-NHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHS 532
Query: 401 AKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVH 460
+ Y CI C K F+ + L+ H +KP + C C +V L H + VH
Sbjct: 533 GEKPYKCIECGKS-FTQKSHLRSHRGIHSGEKP---YKCNECGKVFAQTSQLARHWR-VH 587
Query: 461 EAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYM 520
+ P Y+CN C +D ++L H G + C C
Sbjct: 588 TGEKP-----------YKCNDCGRAFSDRSSLTFHQAIHTG--------EKPYKCHECGK 628
Query: 521 GFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKH 580
F +S L H R++H T ++P Y C+ C + +S L +K
Sbjct: 629 VFRHNSYLATH-RRIH--------------TGEKP----YKCNECGKAFSMHSNLTTHK- 668
Query: 581 IKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCG 640
IH G+K Y CNQCG
Sbjct: 669 -------------VIHTGEK--------------------------------PYKCNQCG 683
Query: 641 AKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCD 700
+T H +TH T C +C K F + SL H IH Y C C
Sbjct: 684 KVFTQNSHLANHQRTH--TGEKPYRCNECGKAFSVRSSLTTHQAIH--TGKKPYKCNECG 739
Query: 701 KQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWD 760
K FT L H +RCT C + F + S+ H+A+ H+ EK+ Y+C C
Sbjct: 740 KVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAI-HTGEKR-YKCNECGKV 797
Query: 761 FRNETDLQLH 770
FR ++L H
Sbjct: 798 FRQSSNLASH 807
Score = 188 bits (477), Expect = 3e-47
Identities = 180/711 (25%), Positives = 266/711 (37%), Gaps = 149/711 (20%)
Query: 128 SRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSD 187
+ S L +++S P+KC C + F + H ++H+G+K Y CSEC F+
Sbjct: 239 NHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRS 298
Query: 188 HLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQK 247
+L IH HT KPYKC C + F +S L H ++H K K
Sbjct: 299 NLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEK----------------PYK 342
Query: 248 CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGE 307
C++C + F +L H H P +C C +LF + + L++H ++H+GE
Sbjct: 343 CNECGKAFRGHSNLTTH-QLIHTGEKP------FKCNECGKLFTQNSHLISHW-RIHTGE 394
Query: 308 KKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSV 365
K C+ C ++F L H H ++P CN Y S
Sbjct: 395 KPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGK----VFRYNSY----------- 439
Query: 366 DSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNK--QLFSSLAVLQ- 422
GR R TG + Y C C K + S+LA Q
Sbjct: 440 ---------------LGRHRRVH-----TG------EKPYKCNECGKAFSMHSNLATHQV 473
Query: 423 IHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFC 482
IH T KP + C C +V L H +++H + P Y+CN C
Sbjct: 474 IHTGT----KPFK---CNECSKVFTQNSQLANH-RRIHTGEKP-----------YKCNEC 514
Query: 483 SEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGS 542
+ + ++L H + H P + C C F S L H R +H SG
Sbjct: 515 GKAFSVRSSLTTH-QAIHSGEKP-------YKCIECGKSFTQKSHLRSH-RGIH---SGE 562
Query: 543 RFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSR 602
+ Y C+ C +F +L +H + +H G+K
Sbjct: 563 K---------------PYKCNEC--GKVFAQTSQLARHWR------------VHTGEKPY 593
Query: 603 ALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTV 660
+ +++SL QA+ TGE Y C++CG + TH + H T
Sbjct: 594 KCNDCGRAFSDRSSLTFHQAI------HTGEKPYKCHECGKVFRHNSYLATHRRIH--TG 645
Query: 661 LPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFV 720
C +C K F +L H IH Y C C K FT L H
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHKVIH--TGEKPYKCNQCGKVFTQNSHLANHQRTHTGEK 703
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
+RC C + F + S+ H A+ H+ KK Y+C C F L H +
Sbjct: 704 PYRCNECGKAFSVRSSLTTHQAI-HTG-KKPYKCNECGKVFTQNAHL---ANHRRIHTGE 758
Query: 781 KVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLR 829
K ++C CG++F L H+ H+ K+Y C C K F L H R
Sbjct: 759 KPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHR 809
Score = 157 bits (398), Expect = 5e-38
Identities = 154/645 (23%), Positives = 231/645 (35%), Gaps = 173/645 (26%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E + C+ C + F S++T H++ + + P +++ SH
Sbjct: 338 EKPYKCNECGKAFRGHSNLTTHQL--------IHTGEKPFKCNECGKLFTQNSHLISHWR 389
Query: 104 GCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDR 163
GE+ PY C C K+FS S L H+ H+ + P+KC C ++F++ R
Sbjct: 390 -IHTGEK------PYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGR 442
Query: 164 HIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQV 223
H ++HTG+K Y C+EC AFS +L H HT KP+KC C + F +S L H ++
Sbjct: 443 HRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRI 502
Query: 224 HERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQC 283
H K KC++C + F L H A H P +C
Sbjct: 503 HTGEK----------------PYKCNECGKAFSVRSSLTTHQA-IHSGEKP------YKC 539
Query: 284 VYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHS 341
+ C + F +++ L +H +HSGEK C+ C + F +L H H ++P CN
Sbjct: 540 IECGKSFTQKSHLRSH-RGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDC 598
Query: 342 NSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQA 401
++ SS T + G K
Sbjct: 599 GR------AFSDRSSLTFHQAIHT----------------GEK----------------- 619
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
Y C C K +F + L H + +KP + C C + NL H K +H
Sbjct: 620 --PYKCHECGK-VFRHNSYLATHRRIHTGEKP---YKCNECGKAFSMHSNLTTH-KVIHT 672
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+CN C +V + L H R G + C C
Sbjct: 673 GEKP-----------YKCNQCGKVFTQNSHLANHQRTHTG--------EKPYRCNECGKA 713
Query: 522 FLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
F SSL H + +H T K+P Y C+ C V N H+
Sbjct: 714 FSVRSSLTTH-QAIH--------------TGKKP----YKCNEC------GKVFTQNAHL 748
Query: 582 KENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGA 641
NH+ IH G+K Y C +CG
Sbjct: 749 -ANHRR-------IHTGEK--------------------------------PYRCTECGK 768
Query: 642 KYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIH 686
+ S TH+ H T + C +C K F +L H +H
Sbjct: 769 AFRVRSSLTTHMAIH--TGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 155 bits (393), Expect = 2e-37
Identities = 157/631 (24%), Positives = 226/631 (35%), Gaps = 110/631 (17%)
Query: 477 YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH 536
Y+CN C + + L H R G + C C F S+L H
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSG--------EKPYKCSECGKTFTVRSNLTIH----- 303
Query: 537 CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIK-------------- 582
V+ T ++P Y C C NS L ++ I
Sbjct: 304 ----------QVIHTGEKP----YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA 349
Query: 583 -ENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQC 639
H N+ IH G+K + + + + L + TGE Y CN+C
Sbjct: 350 FRGHSNL-TTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRI------HTGEKPYKCNEC 402
Query: 640 GAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESC 699
G ++ S H H T C +C K F L +H +H Y C C
Sbjct: 403 GKAFSVRSSLAIHQTIH--TGEKPYKCNECGKVFRYNSYLGRHRRVH--TGEKPYKCNEC 458
Query: 700 DKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCN 758
K F+ +L H + +HT F+C C +VF + H + H+ EK Y+C C
Sbjct: 459 GKAFSMHSNLATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRI-HTGEKP-YKCNECG 515
Query: 759 WDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSK 816
F + L H + + K +KCI CG+SF + L+ H HS K Y C C K
Sbjct: 516 KAFSVRSSL---TTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGK 572
Query: 817 AFHAIILLEKHLREKHCVFETKTPNCGTNGAS-------EQVQKEEVELQTLLTNSQESH 869
F L +H R K +CG + + + E + H
Sbjct: 573 VFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRH 632
Query: 870 NSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGN 929
NS+ + + T E Y C+ CG A++M + L H++ I GE
Sbjct: 633 NSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKV----IHTGEKP------------ 676
Query: 930 YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGN 989
YKCN C + F + L H +TH G K Y C CG+ F +LT H+ H+
Sbjct: 677 YKCNQCGKVFTQNSHLANHQRTHTGE-KPYRCNECGKAFSVRSSLTTHQAIHT-GKKPYK 734
Query: 990 CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNG 1049
C C H ++H + +RC C + L H H TG
Sbjct: 735 CNECGKVFTQNAHLANHRRIHTGEK----PYRCTECGKAFRVRSSLTTHMAIH---TG-- 785
Query: 1050 SAVQTTGRGQHVQKLYKCASCLKEFRSKQDL 1080
+K YKC C K FR +L
Sbjct: 786 ------------EKRYKCNECGKVFRQSSNL 804
Score = 147 bits (370), Expect = 9e-35
Identities = 162/661 (24%), Positives = 229/661 (34%), Gaps = 130/661 (19%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y CN+CG +T + +H + H K C +C K F + +L H IH
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSGEKPYK--CSECGKTFTVRSNLTIHQVIH--TGEKP 312
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y C C K F L H ++C C + F ++ H + H+ EK ++
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLI-HTGEKP-FK 370
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNC 811
C C F + L + H + K +KC CG++F L H T H+ K Y C
Sbjct: 371 CNECGKLFTQNSHL---ISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKC 427
Query: 812 KFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNS 871
C K F L +H R K CG S +S
Sbjct: 428 NECGKVFRYNSYLGRHRRVHTGEKPYKCNECG---------------------KAFSMHS 466
Query: 872 HDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYK 931
+ + + + T + C+ C +T + L NH+ I GE YK
Sbjct: 467 NLATHQVIHTGTKPFKCNECSKVFTQNSQLANHR----RIHTGEKP------------YK 510
Query: 932 CNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCR 991
CN C + F + L H H G K Y C CG+ F L H+ HS C
Sbjct: 511 CNECGKAFSVRSSLTTHQAIHSGE-KPYKCIECGKSFTQKSHLRSHRGIHSGE-KPYKCN 568
Query: 992 ICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSA 1051
C + H ++H + ++C C + + L H H TG
Sbjct: 569 ECGKVFAQTSQLARHWRVHTGEK----PYKCNDCGRAFSDRSSLTFHQAIH---TG---- 617
Query: 1052 VQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGIN 1108
+K YKC C K FR L ++ PY C K+ S N
Sbjct: 618 ----------EKPYKCHECGKVFRHNSYLATHRRIHTGEKPY----KCNECGKAFSMHSN 663
Query: 1109 V-----------PPGTNRPG--LGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQN 1155
+ P N+ G QN +L A + G RC+ C F S L
Sbjct: 664 LTTHKVIHTGEKPYKCNQCGKVFTQNSHL-ANHQRTHTGEKPYRCNECGKAFSVRSSLTT 722
Query: 1156 HIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVA 1215
H Q IH KK Y+C +C VF H+A
Sbjct: 723 H-QAIH----------------------------TGKKPYKCNECGKVFTQ----NAHLA 749
Query: 1216 NH-MIDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQ 1273
NH I G + C C + F + L H+ H+ E +KC C VF Q++ L
Sbjct: 750 NHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGE---KRYKCNECGKVFRQSSNLAS 806
Query: 1274 H 1274
H
Sbjct: 807 H 807
Score = 145 bits (367), Expect = 2e-34
Identities = 154/644 (23%), Positives = 221/644 (34%), Gaps = 128/644 (19%)
Query: 666 CPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCT 725
C +C K F +L H IH Y C C K FT +L H + ++C
Sbjct: 259 CNECGKAFTQNSNLTSHRRIHS--GEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCH 316
Query: 726 LCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKC 785
C +VF + H + H+ EK Y+C C FR ++L H + K KC
Sbjct: 317 ECGKVFRHNSYLATHRRI-HTGEKP-YKCNECGKAFRGHSNL---TTHQLIHTGEKPFKC 371
Query: 786 IFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG 843
CG+ F L H I T K Y C C KAF L H K CG
Sbjct: 372 NECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG 431
Query: 844 TNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQN 903
+NS+ G V T E Y C+ CG A++M + L
Sbjct: 432 ---------------------KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLAT 470
Query: 904 HQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPI 963
HQ+ +P +KCN CS+ F + L H + H G K Y C
Sbjct: 471 HQVIHTGTKP----------------FKCNECSKVFTQNSQLANHRRIHTGE-KPYKCNE 513
Query: 964 CGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCV 1023
CG+ F +LT H+ HS C C + H + H + + ++C
Sbjct: 514 CGKAFSVRSSLTTHQAIHSGEKPY-KCIECGKSFTQKS----HLRSHRGIHSGEKPYKCN 568
Query: 1024 VCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV-- 1081
C + T +L H H TG +K YKC C + F + L
Sbjct: 569 ECGKVFAQTSQLARHWRVH------------TG-----EKPYKCNDCGRAFSDRSSLTFH 611
Query: 1082 -KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRC 1140
+ PY C C + + + + A + G +C
Sbjct: 612 QAIHTGEKPYK-CHECGKVFR-------------------HNSYLATHRRIHTGEKPYKC 651
Query: 1141 SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC 1200
+ C F S L H + IH +K Y+C +C
Sbjct: 652 NECGKAFSMHSNLTTH-KVIHTG----------------------------EKPYKCNQC 682
Query: 1201 QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV 1260
VF + H H ++ + C C + F + L H H+ + +KC
Sbjct: 683 GKVFTQNSHLANHQRTHTGEKP--YRCNECGKAFSVRSSLTTHQAIHTGKK---PYKCNE 737
Query: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C VF Q L H G+ K Y CT+C + F ++ L H
Sbjct: 738 CGKVFTQNAHLANHRRIHTGE--KPYRCTECGKAFRVRSSLTTH 779
Score = 139 bits (351), Expect = 1e-32
Identities = 168/732 (22%), Positives = 247/732 (33%), Gaps = 164/732 (22%)
Query: 287 HELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSP 344
HEL SL+ + +S K C+ C ++F L SH H ++P C+
Sbjct: 236 HEL--NHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGK- 292
Query: 345 SLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVT 404
+ T SNL++ P
Sbjct: 293 -----------TFTVRSNLTIHQVIHTGEKP----------------------------- 312
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C C K +F + L H + +KP + C C + NL H + +H +
Sbjct: 313 YKCHECGK-VFRHNSYLATHRRIHTGEKPYK---CNECGKAFRGHSNLTTH-QLIHTGEK 367
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLT 524
P ++CN C ++ + L H R G + C C F
Sbjct: 368 P-----------FKCNECGKLFTQNSHLISHWRIHTG--------EKPYKCNECGKAFSV 408
Query: 525 DSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKEN 584
SSL H + +H T ++P Y C+ C V + N ++ +
Sbjct: 409 RSSLAIH-QTIH--------------TGEKP----YKCNEC------GKVFRYNSYLGRH 443
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYT 644
+ +H G+K + ++L Q + T + CN+C +T
Sbjct: 444 RR--------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTG----TKPFKCNECSKVFT 491
Query: 645 SLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFT 704
H + H T C +C K F + SL H IH Y C C K FT
Sbjct: 492 QNSQLANHRRIH--TGEKPYKCNECGKAFSVRSSLTTHQAIH--SGEKPYKCIECGKSFT 547
Query: 705 SVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNE 764
L+ H ++C C +VF + H V H+ EK Y+C C F +
Sbjct: 548 QKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRV-HTGEKP-YKCNDCGRAFSDR 605
Query: 765 TDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF--HA 820
+ L H + K +KC CG+ F L H I T K Y C C KAF H+
Sbjct: 606 SSLTF---HQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHS 662
Query: 821 IILLEK--HLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
+ K H EK K CG + NSH + +
Sbjct: 663 NLTTHKVIHTGEK----PYKCNQCG---------------------KVFTQNSHLANHQR 697
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRT 938
T E Y C+ CG A+++ + L HQ +P YKCN C +
Sbjct: 698 THTGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKP----------------YKCNECGKV 741
Query: 939 FFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQ 998
F L H + H G K Y C CG+ F +LT H H+ C C +
Sbjct: 742 FTQNAHLANHRRIHTGE-KPYRCTECGKAFRVRSSLTTHMAIHTGE-KRYKCNECGKVFR 799
Query: 999 SEEEFLEHCQMH 1010
H +MH
Sbjct: 800 QSSNLASHHRMH 811
Score = 137 bits (344), Expect = 9e-32
Identities = 108/399 (27%), Positives = 158/399 (39%), Gaps = 51/399 (12%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS S L H+ H+ PFKC CS++F H ++HTG+K Y C
Sbjct: 452 PYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKC 511
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERN 227
+EC AFS L H H+ KPYKC C + F S L H +H E
Sbjct: 512 NECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECG 571
Query: 228 KDGSQSGSRMEDWKMKDTQK---CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
K +Q+ W++ +K C+ C F L H A H P +C
Sbjct: 572 KVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQA-IHTGEKP------YKCH 624
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN 342
C ++F + L H ++H+GEK C+ C ++F L +H H ++P CN
Sbjct: 625 ECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCG 683
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
T +S+L+ T P G+ + + + T + K
Sbjct: 684 KVF------------TQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT-THQAIHTGK 730
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K +F+ A L H + +KP + C V SL H+ +H
Sbjct: 731 KPYKCNECGK-VFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSL---TTHMA-IHTG 785
Query: 463 QDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHG 501
+ Y+CN C +V + L H R G
Sbjct: 786 EKR-----------YKCNECGKVFRQSSNLASHHRMHTG 813
Score = 109 bits (272), Expect = 2e-23
Identities = 60/192 (31%), Positives = 90/192 (46%), Gaps = 24/192 (12%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS S L H+ H+ + P+KC C ++F H + HTG+K Y C
Sbjct: 648 PYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRC 707
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+EC AFS L H HT KPYKC C + F ++ L H ++H K
Sbjct: 708 NECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEK-------- 759
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+C++C + F L H+A E R +C C ++F + ++L
Sbjct: 760 --------PYRCTECGKAFRVRSSLTTHMA-----IHTGEKR--YKCNECGKVFRQSSNL 804
Query: 297 MNHMEQVHSGEK 308
+H ++H+GEK
Sbjct: 805 ASH-HRMHTGEK 815
Score = 105 bits (263), Expect = 2e-22
Identities = 130/541 (24%), Positives = 185/541 (34%), Gaps = 109/541 (20%)
Query: 780 GKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAF--------HAIILLEKHLR 829
GK +KC CG++F L H HS K Y C C K F H +I H
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVI----HTG 309
Query: 830 EKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCD 889
EK K CG HNS+ + + T E Y C+
Sbjct: 310 EK----PYKCHECG---------------------KVFRHNSYLATHRRIHTGEKPYKCN 344
Query: 890 ICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHM 949
CG A+ + L HQL I GE +KCN C + F + L H
Sbjct: 345 ECGKAFRGHSNLTTHQL----IHTGEKP------------FKCNECGKLFTQNSHLISHW 388
Query: 950 QTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQM 1009
+ H G K Y C CG+ F +L H+ H+ C C + H ++
Sbjct: 389 RIHTGE-KPYKCNECGKAFSVRSSLAIHQTIHTGEKPY-KCNECGKVFRYNSYLGRHRRV 446
Query: 1010 HPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCAS 1069
H + ++C C + + L H H TG K +KC
Sbjct: 447 HTGEKP----YKCNECGKAFSMHSNLATHQVIH---TGT--------------KPFKCNE 485
Query: 1070 CLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSA 1126
C K F L ++ PY C K+ S R L ++ + +
Sbjct: 486 CSKVFTQNSQLANHRRIHTGEKPYK----CNECGKAFSV---------RSSLTTHQAIHS 532
Query: 1127 IEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISP 1186
G +C C F +S L++H E N Q S + R
Sbjct: 533 -------GEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWR 585
Query: 1187 SQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIE 1246
+ EK Y+C C F + + H A H ++ ++C C + F + L H
Sbjct: 586 VHTGEKP-YKCNDCGRAFSDRSSLTFHQAIHTGEKP--YKCHECGKVFRHNSYLATHRRI 642
Query: 1247 HSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTM 1306
H+ E +KC C F + L H G+ K Y C QC + F + L NH
Sbjct: 643 HTGEK---PYKCNECGKAFSMHSNLTTHKVIHTGE--KPYKCNQCGKVFTQNSHLANHQR 697
Query: 1307 T 1307
T
Sbjct: 698 T 698
Score = 91.3 bits (225), Expect = 6e-18
Identities = 116/513 (22%), Positives = 192/513 (37%), Gaps = 69/513 (13%)
Query: 825 EKHLREKHCVFETKTPN------CGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
+K++ + C + T N G +Q + ++E + + S +SH +
Sbjct: 135 QKNVHDFECQWRDDTGNYKGVLMAQKEGKRDQRDRRDIENKLMNNQLGVSFHSHLPELQL 194
Query: 879 VDTSEPMYGCDIC------GAAYT----METLLQNHQLRD-HNIRPGESAIVKKKAELIK 927
MY C+ G++ + + + +Q H+ + H + ++KA
Sbjct: 195 FQGEGKMYECNQVEKSTNNGSSVSPLQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCG 254
Query: 928 GNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDT 987
YKCN C + F + L H + H G K Y C CG+ F LT H+V H+
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGE-KPYKCSECGKTFTVRSNLTIHQVIHTGE-KP 312
Query: 988 GNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTG 1047
C C + H ++H + ++C C + L H H TG
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEK----PYKCNECGKAFRGHSNLTTHQLIH---TG 365
Query: 1048 NGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVN-LSKSA 1103
+K +KC C K F L+ ++ PY C C S +
Sbjct: 366 --------------EKPFKCNECGKLFTQNSHLISHWRIHTGEKPY-KCNECGKAFSVRS 410
Query: 1104 SPGINVPPGTNRPGLGQNE-----NLSAIEGKGK---VGGLKTRCSSCNVKFESESELQN 1155
S I+ T NE ++ G+ + G +C+ C F S L
Sbjct: 411 SLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLAT 470
Query: 1156 HIQTIHRELVP----DSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQ 1211
H Q IH P + + + Q++ RI + K Y+C +C F +
Sbjct: 471 H-QVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGE----KPYKCNECGKAFSVRSSLT 525
Query: 1212 VHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1271
H A H ++ ++C C ++F + L+ H HS E +KC C VF Q ++L
Sbjct: 526 THQAIHSGEK--PYKCIECGKSFTQKSHLRSHRGIHSGE---KPYKCNECGKVFAQTSQL 580
Query: 1272 QQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
+H + H E K Y C C + F ++ L H
Sbjct: 581 ARH-WRVHTGE-KPYKCNDCGRAFSDRSSLTFH 611
Score = 88.2 bits (217), Expect = 5e-17
Identities = 34/87 (39%), Positives = 55/87 (63%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K F++ ++L +H + H+ + P++CT C + F+ + S H+ +HTG+K+Y C
Sbjct: 732 PYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKC 791
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYK 203
+EC F +S +L H + HT KPYK
Sbjct: 792 NECGKVFRQSSNLASHHRMHTGEKPYK 818
>gi|138175817 zinc finger protein 236 [Homo sapiens]
Length = 1845
Score = 187 bits (476), Expect = 4e-47
Identities = 275/1331 (20%), Positives = 473/1331 (35%), Gaps = 228/1331 (17%)
Query: 47 HSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTC-------SWPASSPS-----SK 94
H CD C Q F ++T HK +DPTC S AS + K
Sbjct: 66 HRCDQCPQTFNVEFNLTLHKCTHS--------GEDPTCPVCNKKFSRVASLKAHIMLHEK 117
Query: 95 DQTSPSHGEGCDF------------GEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSH-- 140
++ G +F +E + C+ C K F S LK H ++H
Sbjct: 118 EENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYK 177
Query: 141 --------------SDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRS 186
+ C +C + F+ RHI++HTG++ + CSEC AF++
Sbjct: 178 IRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK 237
Query: 187 DHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQ-VHERNKDGSQSGSRMEDWKMKDT 245
L+ H+ HT KP+ CA C F +L H+Q VH K+G T
Sbjct: 238 GALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNG-------------PT 284
Query: 246 QKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHS 305
C++C F L HI++ H N + + L Q S
Sbjct: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
Query: 306 GEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPS---LVTVGYTS--VSSTTPD 360
+ S S+ + EL S P S P +TVG + +
Sbjct: 345 ASSQPSSQAVSDVIQQLLEL-----SEPAPVESGQSPQPGQQLSITVGINQDILQQALEN 399
Query: 361 SNLSVDSSTMVEAAPPIPKSRGRKRAAQ-QTPDMTGPSSKQAKVTYSCIYCNKQLFSSLA 419
S L S++ AA P + A Q PD++ S++Q T + ++ L
Sbjct: 400 SGL----SSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLD 455
Query: 420 VLQ---IHLKTMHL------DKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDP----- 465
+ I K+ L + + H+C YC + +L H++ +H + P
Sbjct: 456 KKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIR-IHTHEKPFKCPQ 514
Query: 466 ----GLIVSAMPAIV--------YQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAF 513
+ S + A + ++C +C + + +L+ HIR G F
Sbjct: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGV--------RPF 566
Query: 514 FCPHCYMGFLTDSSLEEHIRQ--VHCDLSGSRF----GSPVLGTPKEPVVEVYSCSYCTN 567
CPHC F T + HI H +L R +G PV ++
Sbjct: 567 ACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDI-----PLQ 621
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
PI + L L + I +N +Y +N + A P + K
Sbjct: 622 EPILITDLGLIQPIPKNQ----FFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIR 677
Query: 628 ARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTI 685
+ TGE + C+QCG + S + H++TH T L C CN F SL +H+ I
Sbjct: 678 SH-TGEKPFKCSQCGRGFVSAGVLKAHIRTH--TGLKSFKCLICNGAFTTGGSLRRHMGI 734
Query: 686 HFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKH 745
H + Y+C C K F + + +KH+ R L Q++ +H
Sbjct: 735 HNDLRP--YMCPYCQKTFKTSLNCKKHMKT------HRYELAQQL------------QQH 774
Query: 746 SNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTH 805
+ T + T +Q+ ++ + L +V + ++E Q + T
Sbjct: 775 QQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEV---VAANPEAMLDLEPQHVVGTE 831
Query: 806 SKKYNCKFCSKAFHA----IILLEKHLREKHCVFETKTPN-------------CGTNGAS 848
+ + A + + LR FE ++P T+
Sbjct: 832 EAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYH 891
Query: 849 EQVQ---KEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQ 905
+Q Q ++++ + L + S + H S +S+ M L+Q
Sbjct: 892 QQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGM---------NVTTRLIQESS 942
Query: 906 LRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICG 965
+ +++ S ++ + + +Y+C+ C++ F + L++H+++H G K Y C +CG
Sbjct: 943 QEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGE-KPYKCKLCG 1001
Query: 966 ERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVC 1025
F S L H+ TH+ + +C +C + H H S+ ++C C
Sbjct: 1002 RGFVSSGVLKSHEKTHT-GVKAFSCSVCNASFTTNGSLTRHMATH----MSMKPYKCPFC 1056
Query: 1026 MQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDI 1085
+ +T+ K H H SA T G + + S R + V
Sbjct: 1057 EEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFT 1116
Query: 1086 NGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQ-NENLSAIEGKGKVGGLKTRCSSCN 1144
L S + S + V + + + + + ++ + K C+ C
Sbjct: 1117 EEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC---CTYCP 1173
Query: 1145 VKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVF 1204
F+ S+L H++ IH +K Y+C +C F
Sbjct: 1174 KSFKKPSDLVRHVR-IH----------------------------TGEKPYKCDECGKSF 1204
Query: 1205 YNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTV 1264
+ + HV H + + C +CS F + L+ H+ H+ FKCP C
Sbjct: 1205 TVKSTLDCHVKTHTGQKLFS--CHVCSNAFSTKGSLKVHMRLHT---GAKPFKCPHCELR 1259
Query: 1265 FVQANKLQQHI 1275
F + + + H+
Sbjct: 1260 FRTSGRRKTHM 1270
Score = 159 bits (403), Expect = 1e-38
Identities = 149/709 (21%), Positives = 263/709 (37%), Gaps = 100/709 (14%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C +C +++ + +LK H +SH+ + PFKC+ C R F HI+ HTG K + C
Sbjct: 656 PYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERN 227
C+ AF+ L+ H+ H +PY C C++ F +S + HM+ H +
Sbjct: 716 LICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQ 775
Query: 228 KDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCH 287
+ S S ++ M+ + + E + P+ + + +PE A L H
Sbjct: 776 QAASIDDSTVDQQSMQASTQMQVEIESDELPQTAE--VVAANPE-------AMLDLEPQH 826
Query: 288 ELFVEETSLMNHM-EQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSL 346
+ EE L + +Q ++ + + L H+D ++ S P+
Sbjct: 827 VVGTEEAGLGQQLADQPLEADEDGFVA-------PQDPLRGHVDQFEEQSPAQQSFEPAG 879
Query: 347 VTVGYTSVSS-----TTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQA 401
+ G+T + P DSST+ +S+ + Q + PSS
Sbjct: 880 LPQGFTVTDTYHQQPQFPPVQQLQDSSTL--------ESQALSTSFHQQSLLQAPSSDGM 931
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
VT I + Q L + D+ +++ C YC + +L +H++ H
Sbjct: 932 NVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRS-HT 990
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+C C L+ H + G AF C C
Sbjct: 991 GEKP-----------YKCKLCGRGFVSSGVLKSHEKTHTGV--------KAFSCSVCNAS 1031
Query: 522 FLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHI 581
F T+ SL H+ H + + Y C +C F + + KH+
Sbjct: 1032 FTTNGSLTRHM-ATHMSM------------------KPYKCPFCEEG--FRTTVHCKKHM 1070
Query: 582 KENHKNIPLALNYI---------------HNGKKSRALSPLSPVAIEQTSLKMMQAVGGA 626
K H+ +P A++ H+ + + S + + + +
Sbjct: 1071 K-RHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQ 1129
Query: 627 PARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIH 686
+ E + Q A+ + + D C C K F L++HV IH
Sbjct: 1130 ESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIH 1189
Query: 687 FMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHS 746
Y C+ C K FT L H+ F C +C F +K S+++H+ + H+
Sbjct: 1190 --TGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRL-HT 1246
Query: 747 NEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTE 795
K ++C C FR + H++ ++ + K K + S G +
Sbjct: 1247 GAKP-FKCPHCELRFRTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQ 1294
Score = 147 bits (372), Expect = 5e-35
Identities = 252/1202 (20%), Positives = 427/1202 (35%), Gaps = 227/1202 (18%)
Query: 174 YHCSECDAAFSRSDHLKIHLKTHTSN-KPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQ 232
+ C C +F + + H++ H N KP++C C + F +L H H
Sbjct: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTH-------- 88
Query: 233 SGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVE 292
SG + C C + F L+ HI +E L C C + F
Sbjct: 89 SG---------EDPTCPVCNKKFSRVASLKAHIML-------HEKEENLICSECGDEFTL 132
Query: 293 ETSLMNHME---QVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTV 349
++ L HME Q +G ++++C C + F T EL HM +H
Sbjct: 133 QSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH----------------- 175
Query: 350 GYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIY 409
Y S+T N ++D S + P K+ ++ +Q T + + ++ + C
Sbjct: 176 -YKIRVSSTRSYNRNIDRSGFTYSCPHCGKTF--QKPSQLTRHIRIHTGERP---FKCSE 229
Query: 410 CNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIV 469
C K F+ LQ H+ +KP H C +C NL H+++VH G
Sbjct: 230 CGKA-FNQKGALQTHMIKHTGEKP---HACAFCPAAFSQKGNLQSHVQRVHSEVKNGP-- 283
Query: 470 SAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLE 529
Y C CS V L +L HI H MG +S+
Sbjct: 284 ------TYNCTECSCVFKSLGSLNTHISKMH-------------------MGGPQNSTSS 318
Query: 530 EHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIP 589
V L+ + F + L ++ + S S + P +V + + + E + P
Sbjct: 319 TETAHV---LTATLFQTLPL---QQTEAQATSAS---SQPSSQAVSDVIQQLLELSEPAP 369
Query: 590 LALNYIHNGKKSRALSPLS-PVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDS 648
+ +G+ + LS V I Q L+ G + P + + C AK TS
Sbjct: 370 -----VESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAK-TSAPH 423
Query: 649 FQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY-------------YI 695
Q + + T + KE + E L K S + ++
Sbjct: 424 AQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHV 483
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRC 754
C C K+F DL +H+ +HT F+C C F K ++ H +K K ++C
Sbjct: 484 CPYCAKEFRKPSDLVRHIR-IHTHEKPFKCPQCFRAFAVKSTLTAH--IKTHTGIKAFKC 540
Query: 755 TSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCKFC 814
C F L++H++ L + C C + F T + HI +H K
Sbjct: 541 QYCMKSFSTSGSLKVHIR---LHTGVRPFACPHCDKKFRTSGHRKTHIASHFK------- 590
Query: 815 SKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDG 874
H + +H R+ V KT N Q +L + +
Sbjct: 591 ----HTELRKMRHQRKPAKVRVGKT-NIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYF 645
Query: 875 SEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGE--------------SAIVK 920
+ V+ ++ Y C C AY L+ H +R H GE + ++K
Sbjct: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQH-IRSHT---GEKPFKCSQCGRGFVSAGVLK 701
Query: 921 KKAELIKG--NYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHK 978
G ++KC +C+ F + LR HM H ++ YMCP C + F + L +H
Sbjct: 702 AHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH-NDLRPYMCPYCQKTFKTSLNCKKHM 760
Query: 979 VT-----------HSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQ 1027
T H ++ + + + +Q+ QM ++ + V
Sbjct: 761 KTHRYELAQQLQQHQQAASIDDSTVDQQSMQAST------QMQVEIESDELPQTAEVVAA 814
Query: 1028 TVTSTLELKIHGTFHMQKTGNGS---------------AVQTTGRGQHVQKLYKCASCLK 1072
+ L+L+ ++ G G A Q RG HV + + + +
Sbjct: 815 NPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRG-HVDQFEEQSPAQQ 873
Query: 1073 EFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGK 1132
F GLP G + P + Q ++ S +E +
Sbjct: 874 SFEPA---------GLPQGFTVTDTYHQQPQFPPVQ-----------QLQDSSTLESQ-- 911
Query: 1133 VGGLKTRCSSCNVKFESESELQ---NHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQS 1189
+ + F +S LQ + + L+ +S+ +L Q + ++
Sbjct: 912 ---------ALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDL-QAQGSQFLEDNED 961
Query: 1190 DEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSF 1249
+++Y+C C F ++ HV +H ++ ++CKLC + F S L+ H E +
Sbjct: 962 QSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKP--YKCKLCGRGFVSSGVLKSH--EKTH 1017
Query: 1250 EGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQH 1309
G+ F C VC F L +H+ A K Y C C + F + H M +H
Sbjct: 1018 TGV-KAFSCSVCNASFTTNGSLTRHM--ATHMSMKPYKCPFCEEGFRTTVHCKKH-MKRH 1073
Query: 1310 SS 1311
+
Sbjct: 1074 QT 1075
Score = 133 bits (335), Expect = 1e-30
Identities = 179/871 (20%), Positives = 318/871 (36%), Gaps = 210/871 (24%)
Query: 147 KCTYCSRLFKHKRSRDRHIKLHT-GDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCA 205
KC C F + RH++ H DK + C +C F+ +L +H TH+ P C
Sbjct: 38 KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCP 96
Query: 206 ICRRGFLSSSSLHGHMQVHERNKD------------GSQSGSRMEDWKMK----DTQKCS 249
+C + F +SL H+ +HE+ ++ SQ ME+ + + C
Sbjct: 97 VCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACK 156
Query: 250 QCEEGFDFPEDLQKHIAECHP-------ECSPNEDRAAL--QCVYCHELFVEETSLMNHM 300
C++ F+ +L++H+ + + N DR+ C +C + F + + L H+
Sbjct: 157 ACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHI 216
Query: 301 EQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTT 358
++H+GE+ CS C ++F+ L +HM H ++P +C
Sbjct: 217 -RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHAC-------------------- 255
Query: 359 PDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSL 418
P +G ++ Q S + TY+C C+ +F SL
Sbjct: 256 -------------AFCPAAFSQKGNLQSHVQRVH----SEVKNGPTYNCTECS-CVFKSL 297
Query: 419 AVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQ 478
L H+ MH+ P+ + VL + L+Q EAQ S+ P+
Sbjct: 298 GSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQT-EAQ--ATSASSQPS---- 350
Query: 479 CNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCD 538
S+ V+D+ +Q+ + S PA +S P + + + I Q +
Sbjct: 351 ----SQAVSDV--IQQLLELS----EPAPVESGQSPQPGQQLSITV--GINQDILQQALE 398
Query: 539 LSGSRFGSPVLGTPKEPVVEVYSCSYCTN---SPIFNSVLKLNKHIKENHKNIPLALNYI 595
SG P P + S + N S + N +E + P L+
Sbjct: 399 NSGLS-SIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDK- 456
Query: 596 HNGKKSRALSPLSPVAI-EQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLK 654
K + SP P +I E+ ++ ++C C ++ H++
Sbjct: 457 KEKKMIKKKSPFLPGSIREENGVRW--------------HVCPYCAKEFRKPSDLVRHIR 502
Query: 655 THLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLL 714
H T CPQC + F + +L H+ H I + + C+ C K F++ L+ H +
Sbjct: 503 IH--THEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA--FKCQYCMKSFSTSGSLKVH-I 557
Query: 715 DMHTFVF-FRCTLCQEVFDSKVSIQLHLA----------VKHSNEKKVYRCTSCNWDFRN 763
+HT V F C C + F + + H+A ++H + R N +
Sbjct: 558 RLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPD 617
Query: 764 --------ETDL------------QLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHIT 803
TDL Q + +N + + +KC +C ++ L+ HI
Sbjct: 618 IPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIR 677
Query: 804 THS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTL 861
+H+ K + C C + F + +L+ H+R
Sbjct: 678 SHTGEKPFKCSQCGRGFVSAGVLKAHIR-------------------------------- 705
Query: 862 LTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKK 921
+H G + + C IC A+T L+ H +++RP
Sbjct: 706 ---------THTGLKS--------FKCLICNGAFTTGGSLRRHMGIHNDLRP-------- 740
Query: 922 KAELIKGNYKCNVCSRTFFSENGLREHMQTH 952
Y C C +TF + ++HM+TH
Sbjct: 741 --------YMCPYCQKTFKTSLNCKKHMKTH 763
Score = 129 bits (323), Expect = 2e-29
Identities = 196/924 (21%), Positives = 306/924 (33%), Gaps = 219/924 (23%)
Query: 204 CAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQK 263
C C + F S L H+++H K KC QC F L
Sbjct: 484 CPYCAKEFRKPSDLVRHIRIHTHEKPF----------------KCPQCFRAFAVKSTLTA 527
Query: 264 HIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVE 323
HI + A +C YC + F SL H+ ++H+G + +C C + F T
Sbjct: 528 HI-------KTHTGIKAFKCQYCMKSFSTSGSLKVHI-RLHTGVRPFACPHCDKKFRTSG 579
Query: 324 ELYSHMDSH---QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSS-TMVEAAPPIPK 379
+H+ SH + H P+ V VG T++ PD L T + PIPK
Sbjct: 580 HRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIP--VPDIPLQEPILITDLGLIQPIPK 637
Query: 380 SRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHIC 439
+ Q F S + +++ ++ + C
Sbjct: 638 N--------------------------------QFFQS------YFNNNFVNEADRPYKC 659
Query: 440 QYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCS 499
YC +L +H++ H + P ++C+ C L+ HIR
Sbjct: 660 FYCHRAYKKSCHLKQHIRS-HTGEKP-----------FKCSQCGRGFVSAGVLKAHIRTH 707
Query: 500 HGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEV 559
G +F C C F T SL H+ +H DL
Sbjct: 708 TGL--------KSFKCLICNGAFTTGGSLRRHMG-IHNDL------------------RP 740
Query: 560 YSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNG---------KKSRALSPLSPV 610
Y C YC + F + L KH+K + + L ++S S V
Sbjct: 741 YMCPYCQKT--FKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQV 798
Query: 611 AIEQTSLKMM----------------QAVGGAPARPTGEYICNQ-CGAKYTSLDSFQTHL 653
IE L Q V G G+ + +Q A + Q L
Sbjct: 799 EIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPL 858
Query: 654 KTHLDTVLPKLTCPQCNKEFPNQESLLKH-VTIHFMITSTYYI------------CESCD 700
+ H+D Q ++ P Q+S + F +T TY+ + +
Sbjct: 859 RGHVD---------QFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLE 909
Query: 701 KQFTSVDDLQKHLLDMHTFVFFRCT--LCQEVFDSKVSIQLH----LAVKHSNEKKVYRC 754
Q S Q+ LL + T L QE ++ +Q L ++ YRC
Sbjct: 910 SQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRC 969
Query: 755 TSCNWDFRNETDLQLHVK-------------------------HNHLENQGKVHKCIFCG 789
CN F+ + L+ HV+ H K C C
Sbjct: 970 DYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCN 1029
Query: 790 ESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGA 847
SF T L H+ TH K Y C FC + F + +KH++ V + T G
Sbjct: 1030 ASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGG 1089
Query: 848 SEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDIC------GAAYTMETLL 901
+++EE N+ S +V T + A + + L+
Sbjct: 1090 DICMEEEE---------EHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV 1140
Query: 902 QNHQLRDHNIRPGESAIVKKKAEL---IKGNYKCNVCSRTFFSENGLREHMQTHLGPVKH 958
Q+ +D S + K+AEL K C C ++F + L H++ H G K
Sbjct: 1141 QSAAEKDR-----ISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGE-KP 1194
Query: 959 YMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLT 1018
Y C CG+ F TL H TH+ +C +C ++ H ++H +
Sbjct: 1195 YKCDECGKSFTVKSTLDCHVKTHT-GQKLFSCHVCSNAFSTKGSLKVHMRLHTGAK---- 1249
Query: 1019 GFRCVVCMQTVTSTLELKIHGTFH 1042
F+C C ++ K H FH
Sbjct: 1250 PFKCPHCELRFRTSGRRKTHMQFH 1273
Score = 108 bits (270), Expect = 3e-23
Identities = 143/601 (23%), Positives = 216/601 (35%), Gaps = 97/601 (16%)
Query: 721 FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQG 780
F +C +C F + Q H+ H K +RC C F E +L LH K H G
Sbjct: 36 FHKCEICLLSFPKESQFQRHMR-DHERNDKPHRCDQCPQTFNVEFNLTLH-KCTH---SG 90
Query: 781 KVHKCIFCGESFGTEVELQCHITTHSKKYN--CKFCSKAFHAIILLEKHLREKHCVFETK 838
+ C C + F L+ HI H K+ N C C F L H+ E +
Sbjct: 91 EDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEH------R 144
Query: 839 TPNCGTNGASEQVQKEEVELQTLLTNSQESH-----NSHDGSEEDVDTSEPMYGCDICGA 893
GT + + K+E E + L ++H +S ++D S Y C CG
Sbjct: 145 QELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGK 204
Query: 894 AYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHL 953
+ + L H +R H GE +KC+ C + F + L+ HM H
Sbjct: 205 TFQKPSQLTRH-IRIHT---GERP------------FKCSECGKAFNQKGALQTHMIKHT 248
Query: 954 GPVKHYMCPICGERFPSLLTLTEH-KVTHS--KSLDTGNCRICKMPLQSEEEFLEH-CQM 1009
G K + C C F L H + HS K+ T NC C +S H +M
Sbjct: 249 GE-KPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKM 307
Query: 1010 HPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCAS 1069
H + T + T T L + T Q T S + +Q+L + +
Sbjct: 308 HMGGPQNSTSSTETAHVLTATLFQTLPLQQT-EAQATSASSQPSSQAVSDVIQQLLELSE 366
Query: 1070 CLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPG--INVPPGTNRPGLGQ---NENL 1124
V +S PG +++ G N+ L Q N L
Sbjct: 367 ------------------------PAPVESGQSPQPGQQLSITVGINQDILQQALENSGL 402
Query: 1125 SAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRI 1184
S+I SC+ K + + ++ E +++ Q K +
Sbjct: 403 SSIPAAAHPN------DSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQE------- 449
Query: 1185 SPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLN-HECKLCSQTFDSPAKLQCH 1243
SP + D KK + IK + F + + G+ H C C++ F P+ L H
Sbjct: 450 SPEKLD-KKEKKMIKKKSPFL--------PGSIREENGVRWHVCPYCAKEFRKPSDLVRH 500
Query: 1244 LIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQN 1303
+ H+ E FKCP CF F + L HI + G K + C C + F L+
Sbjct: 501 IRIHTHE---KPFKCPQCFRAFAVKSTLTAHIKTHTG--IKAFKCQYCMKSFSTSGSLKV 555
Query: 1304 H 1304
H
Sbjct: 556 H 556
Score = 106 bits (265), Expect = 1e-22
Identities = 86/336 (25%), Positives = 134/336 (39%), Gaps = 42/336 (12%)
Query: 35 PEDGEELEDEAVHSCDSCLQVFES--LSDI--TEHKINQCQLTDGVDVEDDPTCSW---- 86
P+ G++L + D Q E+ LS I H + C +P S
Sbjct: 376 PQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNE 435
Query: 87 ---PASSPSSKDQTSPSHGEGCDFGEEE----GGPGLP-----------YPCQFCDKSFS 128
P + K+Q SP E D E++ P LP + C +C K F
Sbjct: 436 QTDPTDAEQEKEQESP---EKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFR 492
Query: 129 RLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDH 188
+ S L H + H+ + PFKC C R F K + HIK HTG K + C C +FS S
Sbjct: 493 KPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGS 552
Query: 189 LKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKD---- 244
LK+H++ HT +P+ C C + F +S H+ H ++ + + + + K++
Sbjct: 553 LKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTN 612
Query: 245 --------TQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSL 296
+ + G P + NE +C YCH + + L
Sbjct: 613 IPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHL 672
Query: 297 MNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH 332
H+ H+GEK CS C F + L +H+ +H
Sbjct: 673 KQHIRS-HTGEKPFKCSQCGRGFVSAGVLKAHIRTH 707
Score = 99.4 bits (246), Expect = 2e-20
Identities = 43/111 (38%), Positives = 66/111 (59%), Gaps = 8/111 (7%)
Query: 120 CQFCDKSFSRLSYLKHHEQSH------SDKLP--FKCTYCSRLFKHKRSRDRHIKLHTGD 171
C C K+F R ++LK H Q+H S + P FKC C + F +RH ++HTG+
Sbjct: 1688 CPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGE 1747
Query: 172 KKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQ 222
+ +HC+ C+ AF++ L++H+K HT +PYKCA C GF S++ HM+
Sbjct: 1748 RPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
Score = 98.6 bits (244), Expect = 3e-20
Identities = 49/135 (36%), Positives = 69/135 (51%), Gaps = 3/135 (2%)
Query: 90 SPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCT 149
S + KD+ S + + +E P C +C KSF + S L H + H+ + P+KC
Sbjct: 1142 SAAEKDRISELRDKQAELQDE---PKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
Query: 150 YCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRR 209
C + F K + D H+K HTG K + C C AFS LK+H++ HT KP+KC C
Sbjct: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
Query: 210 GFLSSSSLHGHMQVH 224
F +S HMQ H
Sbjct: 1259 RFRTSGRRKTHMQFH 1273
Score = 80.5 bits (197), Expect = 1e-14
Identities = 51/205 (24%), Positives = 84/205 (40%), Gaps = 30/205 (14%)
Query: 108 GEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQS-HSDKLPFKCTYCSRLFKHKRSRDRHIK 166
G + G + C CD++FS + L HH + H + C C + FK H++
Sbjct: 1647 GNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQ 1706
Query: 167 LHTGD--------KKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLH 218
H + + C C+ AF++ L+ H + HT +P+ C +C + F S+L
Sbjct: 1707 THQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQ 1766
Query: 219 GHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDR 278
HM+ H +G R KC+ C GF +++ H+ H ++
Sbjct: 1767 VHMKKH--------TGER--------PYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQES 1810
Query: 279 AALQCVYCHELFVEETSLMNHMEQV 303
A E EE S H+E+V
Sbjct: 1811 AGHP-----EQDGEELSRTLHLEEV 1830
Score = 77.4 bits (189), Expect = 8e-14
Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 7/158 (4%)
Query: 38 GEELEDEA-VHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQ 96
G + E E H C C + F S + + H ++ + P C + +
Sbjct: 1647 GNQPEKEGRAHQCLECDRAFSSAAVLMHHSK---EVHGRERIHGCPVCRKAFKRATHLKE 1703
Query: 97 TSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFK 156
+H G ++ P + + C C+K+F++ S L+ H + H+ + PF CT C + F
Sbjct: 1704 HMQTHQAGPSLSSQK--PRV-FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
Query: 157 HKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLK 194
K + H+K HTG++ Y C+ C F++ ++K+H+K
Sbjct: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
Score = 69.7 bits (169), Expect = 2e-11
Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 14/189 (7%)
Query: 622 AVGGAPARPTGEYICNQCGAKYTSLDSFQTHLK-THLDTVLPKLTCPQCNKEFPNQESLL 680
A G P + + C +C ++S H K H + CP C K F L
Sbjct: 1645 APGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHG--CPVCRKAFKRATHLK 1702
Query: 681 KHVTIHFMITST------YYICESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDS 733
+H+ H S + C++C+K F L++H +HT F CTLC++ F+
Sbjct: 1703 EHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSR-IHTGERPFHCTLCEKAFNQ 1761
Query: 734 KVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFG 793
K ++Q+H+ KH+ E+ Y+C C F +++++LH+K H G + + E G
Sbjct: 1762 KSALQVHMK-KHTGERP-YKCAYCVMGFTQKSNMKLHMKRAH-SYAGALQESAGHPEQDG 1818
Query: 794 TEVELQCHI 802
E+ H+
Sbjct: 1819 EELSRTLHL 1827
Score = 63.5 bits (153), Expect = 1e-09
Identities = 77/370 (20%), Positives = 125/370 (33%), Gaps = 76/370 (20%)
Query: 876 EEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVC 935
E++ D S Y CD C + + L+ H +R H GE YKC +C
Sbjct: 957 EDNEDQSRRSYRCDYCNKGFKKSSHLKQH-VRSHT---GEKP------------YKCKLC 1000
Query: 936 SRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKM 995
R F S L+ H +TH G VK + C +C F + +LT H TH S+ C C+
Sbjct: 1001 GRGFVSSGVLKSHEKTHTG-VKAFSCSVCNASFTTNGSLTRHMATHM-SMKPYKCPFCEE 1058
Query: 996 PLQSEEEFLEHCQMHPDL-------------------------RNSLTGFRCVVCMQTVT 1030
++ +H + H + RN+ R V T
Sbjct: 1059 GFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE 1118
Query: 1031 STLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYK--------------CASCLKEFRS 1076
T +L VQ+ + +L C C K F+
Sbjct: 1119 ETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKK 1178
Query: 1077 KQDL---VKLDINGLPYGL--CAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKG 1131
DL V++ PY C + + + G N + +G
Sbjct: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
Query: 1132 KV------GGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNS-----TQLKTPQVSP 1180
KV G +C C ++F + + H+Q ++ PD T+ + + P
Sbjct: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYK---PDPKKARKPMTRSSSEGLQP 1295
Query: 1181 MPRISPSQSD 1190
+ ++ S +D
Sbjct: 1296 VNLLNSSSTD 1305
Score = 61.6 bits (148), Expect = 5e-09
Identities = 45/191 (23%), Positives = 74/191 (38%), Gaps = 35/191 (18%)
Query: 270 PECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHM 329
P P ++ A QC+ C F LM+H ++VH E+ + C +C ++F L HM
Sbjct: 1646 PGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHM 1705
Query: 330 DSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQ 389
+HQ PSL S+ D+ A P + R ++
Sbjct: 1706 QTHQA--------GPSL---------SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGER 1748
Query: 390 TPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSL 449
+ C C K F+ + LQ+H+K ++P + C YC+
Sbjct: 1749 P--------------FHCTLCEKA-FNQKSALQVHMKKHTGERP---YKCAYCVMGFTQK 1790
Query: 450 YNLNEHLKQVH 460
N+ H+K+ H
Sbjct: 1791 SNMKLHMKRAH 1801
Score = 58.5 bits (140), Expect = 4e-08
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 12/146 (8%)
Query: 696 CESCDKQFTSVDDLQKHLLDMHTFVFFR-CTLCQEVFDSKVSIQLHLAVKH------SNE 748
C CD+ F+S L H ++H C +C++ F ++ H+ S +
Sbjct: 1659 CLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQK 1718
Query: 749 KKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS-- 806
+V++C +C F + L+ +H+ + + C C ++F + LQ H+ H+
Sbjct: 1719 PRVFKCDTCEKAFAKPSQLE---RHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE 1775
Query: 807 KKYNCKFCSKAFHAIILLEKHLREKH 832
+ Y C +C F ++ H++ H
Sbjct: 1776 RPYKCAYCVMGFTQKSNMKLHMKRAH 1801
Score = 54.7 bits (130), Expect = 6e-07
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 17/170 (10%)
Query: 1135 GLKTRCSSCNVKFESESELQNHIQTIH-RELVPD--------SNSTQLKTPQVSPMPRIS 1185
G +C C+ F S + L +H + +H RE + +T LK + +
Sbjct: 1654 GRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH--QAG 1711
Query: 1186 PSQSDEK-KTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHL 1244
PS S +K + ++C C+ F ++ H H + + C LC + F+ + LQ H+
Sbjct: 1712 PSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFH--CTLCEKAFNQKSALQVHM 1769
Query: 1245 IEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQK 1294
+H+ E +KC C F Q + ++ H+ AH + + P++
Sbjct: 1770 KKHTGE---RPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQ 1816
Score = 52.0 bits (123), Expect = 4e-06
Identities = 42/178 (23%), Positives = 66/178 (37%), Gaps = 34/178 (19%)
Query: 910 NIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFP 969
N+ PG + +A ++C C R F S L H + G + + CP+C + F
Sbjct: 1643 NLAPGNQPEKEGRA------HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFK 1696
Query: 970 SLLTLTEHKVTH-------SKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRC 1022
L EH TH S+ C C+ + H ++H R F C
Sbjct: 1697 RATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGER----PFHC 1752
Query: 1023 VVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDL 1080
+C + L++H H TG ++ YKCA C+ F K ++
Sbjct: 1753 TLCEKAFNQKSALQVHMKKH---TG--------------ERPYKCAYCVMGFTQKSNM 1793
Score = 50.8 bits (120), Expect = 8e-06
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Query: 723 RCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHL-----E 777
+C C F S + H H E+ ++ C C F+ T L+ H++ +
Sbjct: 1658 QCLECDRAFSSAAVLMHHSKEVHGRER-IHGCPVCRKAFKRATHLKEHMQTHQAGPSLSS 1716
Query: 778 NQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLRE 830
+ +V KC C ++F +L+ H H+ + ++C C KAF+ L+ H+++
Sbjct: 1717 QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKK 1771
Score = 47.8 bits (112), Expect = 7e-05
Identities = 40/164 (24%), Positives = 58/164 (35%), Gaps = 22/164 (13%)
Query: 431 DKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLN 490
+K +AH C C S L H K+VH + ++ C C +
Sbjct: 1651 EKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRER-----------IHGCPVCRKAFKRAT 1699
Query: 491 TLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHI------RQVHCDLSGSRF 544
L+EH++ + +++ F C C F S LE H R HC L F
Sbjct: 1700 HLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAF 1759
Query: 545 GSP---VLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENH 585
+ K Y C+YC S +KL H+K H
Sbjct: 1760 NQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKL--HMKRAH 1801
Score = 47.8 bits (112), Expect = 7e-05
Identities = 38/158 (24%), Positives = 58/158 (36%), Gaps = 27/158 (17%)
Query: 888 CDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLRE 947
C C A++ +L +H H E I G C VC + F L+E
Sbjct: 1659 CLECDRAFSSAAVLMHHSKEVHG------------RERIHG---CPVCRKAFKRATHLKE 1703
Query: 948 HMQTH-LGPV------KHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSE 1000
HMQTH GP + + C C + F L H H+ +C +C+ +
Sbjct: 1704 HMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF-HCTLCEKAFNQK 1762
Query: 1001 EEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
H + H R ++C C+ T +K+H
Sbjct: 1763 SALQVHMKKHTGERP----YKCAYCVMGFTQKSNMKLH 1796
Score = 45.8 bits (107), Expect = 3e-04
Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 10/130 (7%)
Query: 877 EDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCS 936
++V E ++GC +C A+ T L+ H ++ H P S+ +K + +KC+ C
Sbjct: 1677 KEVHGRERIHGCPVCRKAFKRATHLKEH-MQTHQAGPSLSS---QKPRV----FKCDTCE 1728
Query: 937 RTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMP 996
+ F + L H + H G + + C +C + F L H H+ C C M
Sbjct: 1729 KAFAKPSQLERHSRIHTGE-RPFHCTLCEKAFNQKSALQVHMKKHTGERPY-KCAYCVMG 1786
Query: 997 LQSEEEFLEH 1006
+ H
Sbjct: 1787 FTQKSNMKLH 1796
Score = 42.0 bits (97), Expect = 0.004
Identities = 38/178 (21%), Positives = 68/178 (38%), Gaps = 32/178 (17%)
Query: 807 KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQ 866
+ + C C +AF + +L H +E H + C V ++ + T L
Sbjct: 1655 RAHQCLECDRAFSSAAVLMHHSKEVH--GRERIHGC-------PVCRKAFKRATHLKEHM 1705
Query: 867 ESHNSHDGSEEDVDTSEP-MYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAEL 925
++H + + + +P ++ CD C A+ + L+ H RP
Sbjct: 1706 QTHQ----AGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP------------ 1749
Query: 926 IKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEH-KVTHS 982
+ C +C + F ++ L+ HM+ H G + Y C C F + H K HS
Sbjct: 1750 ----FHCTLCEKAFNQKSALQVHMKKHTGE-RPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
>gi|55769537 zinc finger protein 658 [Homo sapiens]
Length = 1059
Score = 184 bits (467), Expect = 5e-46
Identities = 206/881 (23%), Positives = 315/881 (35%), Gaps = 158/881 (17%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C +FSR S L +++ + F+ C F + H K GDK +
Sbjct: 297 YECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEHN 356
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPY---KCAICRRGFLSSSSLHGHMQVHERNKDGSQSG 234
EC A + H + HT +K Y + CR+ F + L H + H K
Sbjct: 357 ECTDALYQKLDFTAHQRIHTEDKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEK------ 410
Query: 235 SRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNE--DRAALQCVYCHELFVE 292
T + +C + F + HP P +C C + F +
Sbjct: 411 ----------TYQYEECAKSF---------CSSSHPIQHPGTYVGFKLYECNECGKAFCQ 451
Query: 293 ETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYT 352
++L H+ ++H+ EK + C S+ + L H + + E C S G T
Sbjct: 452 NSNLSKHL-RIHTKEKPCDNNGCGRSYKS--PLIGHQKTDAEMELCGGSE------YGKT 502
Query: 353 SVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNK 412
S + +E K+ RA Q+ P Y C+ C K
Sbjct: 503 SHLKGHQRILMGEKPYECIECGKTFSKT-SHLRAHQRIHTGEKP--------YECVECEK 553
Query: 413 QLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAM 472
FS L +H + +KP + C C + L H +++H + P
Sbjct: 554 T-FSHKTHLSVHQRVHTGEKPYE---CNDCGKSFTYNSALRAH-QRIHTGEKP------- 601
Query: 473 PAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHI 532
Y+C+ C + + L+ H R G + C C F S L+ H
Sbjct: 602 ----YECSDCEKTFAHNSALRAHHRIHTG--------EKPYECNECGRSFAHISVLKAHQ 649
Query: 533 RQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLAL 592
R + T ++P Y C+ C S +NS L+ ++ I
Sbjct: 650 R---------------IHTGEKP----YECNECGRSFTYNSALRAHQRI----------- 679
Query: 593 NYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQ 650
H G+K S ++LK+ Q + TGE Y CN+C + + +
Sbjct: 680 ---HTGRKPYECSDCEKTFAHNSALKIHQRIH------TGEKPYECNECEKTFAHNSALR 730
Query: 651 THLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQ 710
H H L + C +C K F + L H IH Y C C K F+ Q
Sbjct: 731 AHQNIHTGEKLYE--CSECGKTFFQKTRLSTHRRIH--TGEKPYECSKCGKTFS-----Q 781
Query: 711 KHLLDMHTFVF-----FRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNET 765
K L H + + C +C + F K ++ +H + H+ EK Y C C F T
Sbjct: 782 KSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRI-HTGEKP-YECNQCGKTFSQRT 839
Query: 766 DLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIIL 823
L H + K ++C CG++F L+ H I T K Y C C K F
Sbjct: 840 HL---CAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSH 896
Query: 824 LEKHLREKHCVFETKTPNCGTN-------GASEQVQKEEVELQTLLTNSQESHNSHDGSE 876
L HLR + + CG A ++V E + + +HNS
Sbjct: 897 LRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVH 956
Query: 877 EDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCS 936
+ + T E Y C+ CG ++ ++ L HQ I GE Y+CN C
Sbjct: 957 QRIHTGEKSYECNDCGKTFSQKSHLSAHQ----RIHTGEKP------------YECNECG 1000
Query: 937 RTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEH 977
+ F + LR H + H G K Y C CG+ F L H
Sbjct: 1001 KAFAQNSTLRVHQRIHTGE-KPYECDECGKTFVRKAALRVH 1040
Score = 180 bits (457), Expect = 7e-45
Identities = 163/703 (23%), Positives = 274/703 (38%), Gaps = 125/703 (17%)
Query: 46 VHSCDSCLQVFESLSDITEH-----KINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPS 100
++ C+ C + F S++++H K C D+ C SP Q + +
Sbjct: 439 LYECNECGKAFCQNSNLSKHLRIHTKEKPC---------DNNGCGRSYKSPLIGHQKTDA 489
Query: 101 HGEGC---DFGEEEGGPG--------LPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCT 149
E C ++G+ G PY C C K+FS+ S+L+ H++ H+ + P++C
Sbjct: 490 EMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECV 549
Query: 150 YCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRR 209
C + F HK H ++HTG+K Y C++C +F+ + L+ H + HT KPY+C+ C +
Sbjct: 550 ECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEK 609
Query: 210 GFLSSSSLHGHMQVH--ERNKDGSQSGSRMEDWKM----------KDTQKCSQCEEGFDF 257
F +S+L H ++H E+ + ++ G + + +C++C F +
Sbjct: 610 TFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTY 669
Query: 258 PEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSE 317
L+ H H P E C C + F ++L H +++H+GEK C+ C +
Sbjct: 670 NSALRAH-QRIHTGRKPYE------CSDCEKTFAHNSALKIH-QRIHTGEKPYECNECEK 721
Query: 318 SFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPI 377
+F L +H + H + S G T T ++ + + P
Sbjct: 722 TFAHNSALRAHQNIHTGEKLYECSE------CGKTFFQKTRLSTHRRIHT-----GEKPY 770
Query: 378 PKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAH 437
S+ K +Q++ + Y C C K F A L +H + +KP +
Sbjct: 771 ECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGK-TFVYKAALIVHQRIHTGEKPYE-- 827
Query: 438 ICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIR 497
C C + +L H +++H + P Y+CN C + D + L+ H R
Sbjct: 828 -CNQCGKTFSQRTHLCAH-QRIHTGEKP-----------YECNECGKTFADNSALRAHHR 874
Query: 498 CSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVV 557
G + C C F S L H+R +R G
Sbjct: 875 IHTG--------EKPYECNDCGKTFSKTSHLRAHLR--------TRSGE----------- 907
Query: 558 EVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSL 617
+ Y CS C + + K+ A +H G+K + ++L
Sbjct: 908 KPYECSECGKT--------------FSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTL 953
Query: 618 KMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPN 675
++ Q + TGE Y CN CG ++ H + H T C +C K F
Sbjct: 954 RVHQRI------HTGEKSYECNDCGKTFSQKSHLSAHQRIH--TGEKPYECNECGKAFAQ 1005
Query: 676 QESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHT 718
+L H IH Y C+ C K F L+ H MHT
Sbjct: 1006 NSTLRVHQRIH--TGEKPYECDECGKTFVRKAALRVHHTRMHT 1046
Score = 167 bits (422), Expect = 8e-41
Identities = 185/811 (22%), Positives = 292/811 (36%), Gaps = 178/811 (21%)
Query: 123 CDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAA 182
C KSF R ++L H++ HS + ++ C++ F +H + G K Y C+EC A
Sbjct: 389 CRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKA 448
Query: 183 FSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNK--DGSQSGSRMEDW 240
F ++ +L HL+ HT KP C R + S L GH + + GS+ G
Sbjct: 449 FCQNSNLSKHLRIHTKEKPCDNNGCGRSY--KSPLIGHQKTDAEMELCGGSEYGKTSH-- 504
Query: 241 KMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHM 300
+K Q+ E+ ++ C+ C + F + + L H
Sbjct: 505 -LKGHQRILMGEKPYE--------------------------CIECGKTFSKTSHLRAH- 536
Query: 301 EQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTT 358
+++H+GEK C C ++F L H H ++P CN +T S+
Sbjct: 537 QRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGK------SFTYNSALR 590
Query: 359 PDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSL 418
+ P S K A + + Y C C + F+ +
Sbjct: 591 AHQRIHTGEK-------PYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRS-FAHI 642
Query: 419 AVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQ 478
+VL+ H + +KP + C C L H +++H + P Y+
Sbjct: 643 SVLKAHQRIHTGEKPYE---CNECGRSFTYNSALRAH-QRIHTGRKP-----------YE 687
Query: 479 CNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH-- 536
C+ C + + L+ H R G + C C F +S+L H + +H
Sbjct: 688 CSDCEKTFAHNSALKIHQRIHTG--------EKPYECNECEKTFAHNSALRAH-QNIHTG 738
Query: 537 -----CDLSGSRFGSPV-------LGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKEN 584
C G F + T ++P Y CS C + F+ L+ H +
Sbjct: 739 EKLYECSECGKTFFQKTRLSTHRRIHTGEKP----YECSKCGKT--FSQKSYLSGHER-- 790
Query: 585 HKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAK 642
IH G+K + + + +L + Q + TGE Y CNQCG
Sbjct: 791 ----------IHTGEKPYECNVCGKTFVYKAALIVHQRIH------TGEKPYECNQCGKT 834
Query: 643 YTSLDSFQTHLKTH--LDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCD 700
++ +THL H + T C +C K F + +L H IH Y C C
Sbjct: 835 FSQ----RTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIH--TGEKPYECNDCG 888
Query: 701 KQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWD 760
K F+ L+ HL + C+ C + F K + H V H+ EK Y C C
Sbjct: 889 KTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRV-HTGEKP-YECNVCGKP 946
Query: 761 FRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAF 818
F + + L++H + + K ++C CG++F + L H I T K Y C C KAF
Sbjct: 947 FAHNSTLRVHQR---IHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAF 1003
Query: 819 HAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEED 878
L H R
Sbjct: 1004 AQNSTLRVHQR------------------------------------------------- 1014
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDH 909
+ T E Y CD CG + + L+ H R H
Sbjct: 1015 IHTGEKPYECDECGKTFVRKAALRVHHTRMH 1045
Score = 142 bits (358), Expect = 2e-33
Identities = 160/702 (22%), Positives = 257/702 (36%), Gaps = 120/702 (17%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQ--CNKEFPNQESLLKHVTIHFMITS 691
Y CN+CG + + HL+ H + C C + + + L+ H
Sbjct: 440 YECNECGKAFCQNSNLSKHLRIHTK----EKPCDNNGCGRSY--KSPLIGH-------QK 486
Query: 692 TYYICESCD-KQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKK 750
T E C ++ L+ H + + C C + F ++ H + H+ EK
Sbjct: 487 TDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRI-HTGEKP 545
Query: 751 VYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKK 808
Y C C F ++T L +H + + E K ++C CG+SF L+ H I T K
Sbjct: 546 -YECVECEKTFSHKTHLSVHQRVHTGE---KPYECNDCGKSFTYNSALRAHQRIHTGEKP 601
Query: 809 YNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQES 868
Y C C K F L H R + CG + A V K
Sbjct: 602 YECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLK--------------- 646
Query: 869 HNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKK------- 921
+ + + T E Y C+ CG ++T + L+ HQ +P E + +K
Sbjct: 647 ------AHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSA 700
Query: 922 -----KAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTE 976
+ + Y+CN C +TF + LR H H G K Y C CG+ F L+
Sbjct: 701 LKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGE-KLYECSECGKTFFQKTRLST 759
Query: 977 HKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELK 1036
H+ H+ C C + H ++H + + C VC +T L
Sbjct: 760 HRRIHTGEKPY-ECSKCGKTFSQKSYLSGHERIHTGEKP----YECNVCGKTFVYKAALI 814
Query: 1037 IHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLC 1093
+H H TG +K Y+C C K F + L ++ PY
Sbjct: 815 VHQRIH------------TG-----EKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYE-- 855
Query: 1094 AGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV--GGLKTRCSSCNVKFESES 1151
C K+ + SA+ ++ G C+ C F S
Sbjct: 856 --CNECGKTFADN------------------SALRAHHRIHTGEKPYECNDCGKTFSKTS 895
Query: 1152 ELQNHIQTIHREL---VPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEW 1208
L+ H++T E + T + VS R+ + K Y+C C F +
Sbjct: 896 HLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGE----KPYECNVCGKPFAHNS 951
Query: 1209 DIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQA 1268
++VH H ++ ++EC C +TF + L H H+ E ++C C F Q
Sbjct: 952 TLRVHQRIHTGEK--SYECNDCGKTFSQKSHLSAHQRIHTGE---KPYECNECGKAFAQN 1006
Query: 1269 NKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHS 1310
+ L+ H G +K Y+C +C + F + L+ H H+
Sbjct: 1007 STLRVHQRIHTG--EKPYECDECGKTFVRKAALRVHHTRMHT 1046
Score = 134 bits (337), Expect = 6e-31
Identities = 166/718 (23%), Positives = 253/718 (35%), Gaps = 139/718 (19%)
Query: 637 NQC-GAKYTSLDSFQTHLKTHL-DTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYY 694
N+C A Y LD F H + H D +C K F + L++H H + Y
Sbjct: 356 NECTDALYQKLD-FTAHQRIHTEDKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQY 414
Query: 695 ICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRC 754
E C K F S +H F + C C + F ++ HL + H+ EK
Sbjct: 415 --EECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRI-HTKEKPCDN- 470
Query: 755 TSCNWDFRN------ETDLQLHV-------KHNHLENQGKV------HKCIFCGESFGTE 795
C +++ +TD ++ + K +HL+ ++ ++CI CG++F
Sbjct: 471 NGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKT 530
Query: 796 VELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQK 853
L+ H I T K Y C C K F
Sbjct: 531 SHLRAHQRIHTGEKPYECVECEKTF----------------------------------- 555
Query: 854 EEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRP 913
SH +H + V T E Y C+ CG ++T + L+ HQ I
Sbjct: 556 --------------SHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQ----RIHT 597
Query: 914 GESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLT 973
GE Y+C+ C +TF + LR H + H G K Y C CG F +
Sbjct: 598 GEKP------------YECSDCEKTFAHNSALRAHHRIHTGE-KPYECNECGRSFAHISV 644
Query: 974 LTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTL 1033
L H+ H+ C C H ++H + + C C +T
Sbjct: 645 LKAHQRIHTGE-KPYECNECGRSFTYNSALRAHQRIHTGRK----PYECSDCEKTFAHNS 699
Query: 1034 ELKIHGTFH----------MQKT-GNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV- 1081
LKIH H +KT + SA++ +KLY+C+ C K F K L
Sbjct: 700 ALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLST 759
Query: 1082 --KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV------ 1133
++ PY C+ C S G R G+ + GK V
Sbjct: 760 HRRIHTGEKPYE-CSKCGKTFSQKS----YLSGHERIHTGEKPYECNVCGKTFVYKAALI 814
Query: 1134 -------GGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISP 1186
G C+ C F + L H Q IH P + KT + R
Sbjct: 815 VHQRIHTGEKPYECNQCGKTFSQRTHLCAH-QRIHTGEKPYECNECGKTFADNSALRAHH 873
Query: 1187 SQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIE 1246
+K Y+C C F ++ H+ ++ +EC C +TF + + H
Sbjct: 874 RIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEK--PYECSECGKTFSEKSYVSAHQRV 931
Query: 1247 HSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
H+ E ++C VC F + L+ H G +K Y+C C + F ++ L H
Sbjct: 932 HTGE---KPYECNVCGKPFAHNSTLRVHQRIHTG--EKSYECNDCGKTFSQKSHLSAH 984
Score = 121 bits (303), Expect = 5e-27
Identities = 66/238 (27%), Positives = 112/238 (47%), Gaps = 23/238 (9%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+FS+ ++L H++ H+ + P++C C + F + H ++HTG+K Y C
Sbjct: 825 PYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYEC 884
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKD------- 229
++C FS++ HL+ HL+T + KPY+C+ C + F S + H +VH K
Sbjct: 885 NDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCG 944
Query: 230 -----GSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
S + + +C+ C + F L H H P E C
Sbjct: 945 KPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAH-QRIHTGEKPYE------CN 997
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSH---MDSHQQPESCN 339
C + F + ++L H +++H+GEK C C ++F L H M + ++ +CN
Sbjct: 998 ECGKAFAQNSTLRVH-QRIHTGEKPYECDECGKTFVRKAALRVHHTRMHTREKTLACN 1054
Score = 99.4 bits (246), Expect = 2e-20
Identities = 59/205 (28%), Positives = 94/205 (45%), Gaps = 21/205 (10%)
Query: 25 DGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTC 84
D AL R GE+ + C+ C + F S + H + E C
Sbjct: 865 DNSALRAHHRIHTGEK-----PYECNDCGKTFSKTSHLRAHLRTRSG-------EKPYEC 912
Query: 85 SWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKL 144
S + S K S + GE+ PY C C K F+ S L+ H++ H+ +
Sbjct: 913 SECGKTFSEKSYVSAH--QRVHTGEK------PYECNVCGKPFAHNSTLRVHQRIHTGEK 964
Query: 145 PFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKC 204
++C C + F K H ++HTG+K Y C+EC AF+++ L++H + HT KPY+C
Sbjct: 965 SYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRIHTGEKPYEC 1024
Query: 205 AICRRGFLSSSSLH-GHMQVHERNK 228
C + F+ ++L H ++H R K
Sbjct: 1025 DECGKTFVRKAALRVHHTRMHTREK 1049
>gi|62243640 zinc finger protein 107 [Homo sapiens]
Length = 783
Score = 179 bits (453), Expect = 2e-44
Identities = 181/737 (24%), Positives = 282/737 (38%), Gaps = 101/737 (13%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+ C+ C KSF LS L H + H+ +KC C + F + +H ++HTG+K Y C
Sbjct: 104 FKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCE 163
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERNK 228
EC AF++S L H HT KP KC C + F +S L H +H E K
Sbjct: 164 ECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGK 223
Query: 229 DGSQSGSRMEDWKMKDT----QKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
SQS S + K+ T KC +C + F+ +L H H P +C
Sbjct: 224 VFSQS-SHLTTQKILHTGENLYKCKECGKAFNLFSNLTNH-KRIHAGEKP------YKCK 275
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMD--SHQQPESCNHSN 342
C F +S +N E++H+G K N C C ++F+ +L +H ++P C
Sbjct: 276 ECGRAF-NISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECG 334
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSS-KQA 401
+ S+ T ++ K + +A Q+ ++T A
Sbjct: 335 KV------FNQFSTLT--------RHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTA 380
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
+ +Y C C K F+ + L H K +KP + C+ C + L H K++H
Sbjct: 381 EKSYKCEECGK-AFNQHSNLINHRKIYSGEKP---YKCEECGKAFNRSSTLTRH-KKIHT 435
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+C C + + L EH + G + C C
Sbjct: 436 GEKP-----------YKCEECDRAFSQSSNLTEHKKIHTG--------EKPYKCEECGKA 476
Query: 522 FLTDSSLEEHIRQVH-------CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSV 574
F S+L +H +++H C+ G F T + V + C F
Sbjct: 477 FNRFSTLTKH-KRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEE---FGKA 532
Query: 575 LKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE- 633
K + H + HK IH G+K V + ++L + + TGE
Sbjct: 533 FKQSSH-RTIHK-------IIHTGEKPYKCEEHGKVFNQSSNLTTQKII------HTGEN 578
Query: 634 -YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITST 692
Y + G + + H + K C +C K + +L H IH
Sbjct: 579 LYKFEEHGKAFNLFSNITNHKIIYTGEKPHK--CEECGKAYNRFSNLTIHKRIH--TGEK 634
Query: 693 YYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVY 752
Y C C K F L +H + ++C C + F+ ++ H + H+ EK Y
Sbjct: 635 PYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKI-HTGEKP-Y 692
Query: 753 RCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYN 810
+C C F ++L H K + K +KC CG+SF L H I T K Y
Sbjct: 693 KCEECGKAFNQSSNLTTHKK---IHTSEKPYKCEECGKSFNQFSSLNIHKIIHTGEKPYK 749
Query: 811 CKFCSKAFHAIILLEKH 827
C +AF+ L H
Sbjct: 750 CGDYGRAFNLSSNLTTH 766
Score = 171 bits (432), Expect = 6e-42
Identities = 186/789 (23%), Positives = 284/789 (35%), Gaps = 138/789 (17%)
Query: 49 CDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFG 108
C C + F LS +T+H+ ++ E +W ++ K + G
Sbjct: 106 CKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHT---------G 156
Query: 109 EEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLH 168
E+ PY C+ C K+F++ S L H+ H+++ P KC C + FK H +H
Sbjct: 157 EK------PYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIH 210
Query: 169 TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNK 228
TG+K Y EC FS+S HL HT YKC C + F S+L H ++H K
Sbjct: 211 TGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEK 270
Query: 229 DGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHE 288
KC +C F+ +L K + H N +C C +
Sbjct: 271 ----------------PYKCKECGRAFNISSNLNKQ-EKIHTGGKLN------KCEECDK 307
Query: 289 LFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSL 346
F L H +++ EK C C + F+ L H H ++P C
Sbjct: 308 AFNRSLKLTAH-KKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECG---- 362
Query: 347 VTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSS-KQAKVTY 405
+ SNL+ + A K +A Q ++ + Y
Sbjct: 363 --------KAFNQSSNLT--EHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPY 412
Query: 406 SCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDP 465
C C K F+ + L H K +KP + C+ C NL EH K++H + P
Sbjct: 413 KCEECGK-AFNRSSTLTRHKKIHTGEKP---YKCEECDRAFSQSSNLTEH-KKIHTGEKP 467
Query: 466 GLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTD 525
Y+C C + N +TL +H R G + C C F
Sbjct: 468 -----------YKCEECGKAFNRFSTLTKHKRIHTG--------EKPYKCEECGKAFNQS 508
Query: 526 SSLEEHIRQVH-------CDLSGSRFGS-------PVLGTPKEPVVEVYSCSYCTNSPIF 571
L H + VH C+ G F ++ T ++P Y C + +F
Sbjct: 509 YQLTRH-KIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKP----YKCE--EHGKVF 561
Query: 572 NSVLKLNK----HIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
N L H EN + +GK S ++ I T K
Sbjct: 562 NQSSNLTTQKIIHTGEN------LYKFEEHGKAFNLFSNITNHKIIYTGEK--------- 606
Query: 628 ARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
+ C +CG Y + H + H T C +C K F +L +H IH
Sbjct: 607 -----PHKCEECGKAYNRFSNLTIHKRIH--TGEKPYQCAECGKAFNCSSTLNRHKIIH- 658
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHS 746
Y C+ C K F L H +HT ++C C + F+ ++ H + H+
Sbjct: 659 -TGEKPYKCKECGKAFNLSSTLTAH-KKIHTGEKPYKCEECGKAFNQSSNLTTHKKI-HT 715
Query: 747 NEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITT 804
+EK Y+C C F + L + H + K +KC G +F L H I T
Sbjct: 716 SEKP-YKCEECGKSFNQFSSLNI---HKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHT 771
Query: 805 HSKKYNCKF 813
K Y C++
Sbjct: 772 GEKPYKCEY 780
Score = 150 bits (380), Expect = 6e-36
Identities = 196/912 (21%), Positives = 310/912 (33%), Gaps = 204/912 (22%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSD-KLPFKCTYCSRLFKHKRSRD--RHIKLHTGDKKY 174
+P Q SF +++ ++ + + + +L C + HK + T K +
Sbjct: 17 WPEQNIKDSFQKVTLRRYGKCEYENLQLRKGCKHVDECTGHKGGHNTVNQCLTATPSKIF 76
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSG 234
C++ F + + + + HT NK +KC C + F S L H ++H R
Sbjct: 77 QCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTR-------- 128
Query: 235 SRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEET 294
++ KC +C + F++ L KH H P +C C + F + +
Sbjct: 129 --------VNSYKCEECGKAFNWFSTLTKH-KRIHTGEKP------YKCEECGKAFNQSS 173
Query: 295 SLMNHMEQVHSGEKKNSCSICSESF------------HTVEELYSHMDSHQQPESCNHSN 342
L H + +H+ EK N C C ++F HT E+ Y + + + +H
Sbjct: 174 QLTRH-KIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLT 232
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
+ ++ G ++ S+ + + + + +++ +KQ K
Sbjct: 233 TQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEK 292
Query: 403 V-----TYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLK 457
+ C C+K SL L H K + +KP + C+ C +V L H K
Sbjct: 293 IHTGGKLNKCEECDKAFNRSLK-LTAHKKILMEEKP---YKCEECGKVFNQFSTLTRH-K 347
Query: 458 QVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPH 517
+H + P Y+C C + N + L EH + ++ C
Sbjct: 348 IIHTGEKP-----------YKCKECGKAFNQSSNLTEHKKIHTA--------EKSYKCEE 388
Query: 518 CYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKL 577
C F S+L H R+++ SG + Y C C + FN L
Sbjct: 389 CGKAFNQHSNLINH-RKIY---SGEK---------------PYKCEECGKA--FNRSSTL 427
Query: 578 NKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICN 637
+H K IH G+K Y C
Sbjct: 428 TRHKK------------IHTGEK--------------------------------PYKCE 443
Query: 638 QCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICE 697
+C ++ + H K H T C +C K F +L KH IH Y CE
Sbjct: 444 ECDRAFSQSSNLTEHKKIH--TGEKPYKCEECGKAFNRFSTLTKHKRIH--TGEKPYKCE 499
Query: 698 SCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSC 757
C K F L +H + +C + F +H + H+ EK Y+C
Sbjct: 500 ECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKII-HTGEKP-YKCEEH 557
Query: 758 NWDFRNETDLQ----LHVKHN--HLENQGKV-------------------HKCIFCGESF 792
F ++L +H N E GK HKC CG+++
Sbjct: 558 GKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAY 617
Query: 793 GTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQ 850
L H I T K Y C C KAF+ L +H K CG
Sbjct: 618 NRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECG------- 670
Query: 851 VQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHN 910
+ L + LT ++ H T E Y C+ CG A+ + L H
Sbjct: 671 ---KAFNLSSTLTAHKKIH-----------TGEKPYKCEECGKAFNQSSNLTTH------ 710
Query: 911 IRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPS 970
KK + YKC C ++F + L H H G K Y C G F
Sbjct: 711 ----------KKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHTGE-KPYKCGDYGRAFNL 759
Query: 971 LLTLTEHKVTHS 982
LT HK H+
Sbjct: 760 SSNLTTHKKIHT 771
Score = 138 bits (347), Expect = 4e-32
Identities = 132/573 (23%), Positives = 217/573 (37%), Gaps = 111/573 (19%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E ++ C C + F S++T HK ++ G C + S+ ++ H
Sbjct: 241 ENLYKCKECGKAFNLFSNLTNHK----RIHAGEKPYKCKECGRAFNISSNLNKQEKIHTG 296
Query: 104 G----CDFGEEEGGPGL-------------PYPCQFCDKSFSRLSYLKHHEQSHSDKLPF 146
G C+ ++ L PY C+ C K F++ S L H+ H+ + P+
Sbjct: 297 GKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPY 356
Query: 147 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAI 206
KC C + F + H K+HT +K Y C EC AF++ +L H K ++ KPYKC
Sbjct: 357 KCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEE 416
Query: 207 CRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIA 266
C + F SS+L H ++H K KC +C+ F +L +H
Sbjct: 417 CGKAFNRSSTLTRHKKIHTGEK----------------PYKCEECDRAFSQSSNLTEH-K 459
Query: 267 ECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESF------- 319
+ H P +C C + F ++L H +++H+GEK C C ++F
Sbjct: 460 KIHTGEKP------YKCEECGKAFNRFSTLTKH-KRIHTGEKPYKCEECGKAFNQSYQLT 512
Query: 320 -----HTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSST------TPDSNLSVDSS 368
HT E+L + + + +H ++ G SNL+ +
Sbjct: 513 RHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLT--TQ 570
Query: 369 TMVEAAPPIPKSRGRKRAAQQTPDMTGPS-SKQAKVTYSCIYCNKQLFSSLAVLQIHLKT 427
++ + K +A ++T + + C C K ++ + L IH +
Sbjct: 571 KIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGK-AYNRFSNLTIHKRI 629
Query: 428 MHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVN 487
+KP Q C C + LN H K +H + P Y+C C + N
Sbjct: 630 HTGEKPYQ---CAECGKAFNCSSTLNRH-KIIHTGEKP-----------YKCKECGKAFN 674
Query: 488 DLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSP 547
+TL H + G + C C F S+L H +++H
Sbjct: 675 LSSTLTAHKKIHTG--------EKPYKCEECGKAFNQSSNLTTH-KKIH----------- 714
Query: 548 VLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKH 580
T ++P Y C C S FN LN H
Sbjct: 715 ---TSEKP----YKCEECGKS--FNQFSSLNIH 738
Score = 134 bits (338), Expect = 4e-31
Identities = 178/847 (21%), Positives = 293/847 (34%), Gaps = 189/847 (22%)
Query: 469 VSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSL 528
++A P+ ++QCN +V + + + R G + F C C F S L
Sbjct: 68 LTATPSKIFQCNKYVKVFDKFSNSNRYKRRHTG--------NKHFKCKECSKSFCVLSQL 119
Query: 529 EEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNI 588
+H R++H ++ Y C C + FN L KH +
Sbjct: 120 TQH-RRIHTRVNS------------------YKCEECGKA--FNWFSTLTKHKR------ 152
Query: 589 PLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDS 648
IH G+K Y C +CG +
Sbjct: 153 ------IHTGEKP--------------------------------YKCEECGKAFNQSSQ 174
Query: 649 FQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDD 708
H H + K C +C K F L H IH Y E C K F+
Sbjct: 175 LTRHKIIHTEEKPNK--CEECGKAFKQASHLTIHKIIH--TGEKPYKYEECGKVFSQSSH 230
Query: 709 LQKHLLDMHTFV-FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDL 767
L + +HT ++C C + F+ ++ H + H+ EK Y+C C F ++L
Sbjct: 231 LTTQKI-LHTGENLYKCKECGKAFNLFSNLTNHKRI-HAGEKP-YKCKECGRAFNISSNL 287
Query: 768 QLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLE 825
K + GK++KC C ++F ++L H I K Y C+ C K F+ L
Sbjct: 288 N---KQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLT 344
Query: 826 KHLREKHCVFETKTPNCGT--NGASEQVQKEEVELQTLLTNSQE---SHNSHDG--SEED 878
+H K CG N +S + +++ +E + N H +
Sbjct: 345 RHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRK 404
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRP------------GESAIVKKKAELI 926
+ + E Y C+ CG A+ + L H+ +P + KK
Sbjct: 405 IYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTG 464
Query: 927 KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKS-- 984
+ YKC C + F + L +H + H G K Y C CG+ F LT HK+ H+K
Sbjct: 465 EKPYKCEECGKAFNRFSTLTKHKRIHTGE-KPYKCEECGKAFNQSYQLTRHKIVHTKEKL 523
Query: 985 ----------LDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLE 1034
+ + I K+ E+ + C+ H + N + + T + +
Sbjct: 524 NKCEEFGKAFKQSSHRTIHKIIHTGEKPY--KCEEHGKVFNQSSNLTTQKIIHTGENLYK 581
Query: 1035 LKIHG-TFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPY 1090
+ HG F++ + TG +K +KC C K + +L ++ PY
Sbjct: 582 FEEHGKAFNLFSNITNHKIIYTG-----EKPHKCEECGKAYNRFSNLTIHKRIHTGEKPY 636
Query: 1091 GLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV---GGLKTRCSSCNVKF 1147
CA C G+ N S+ + K+ G +C C F
Sbjct: 637 -QCAEC----------------------GKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 673
Query: 1148 ESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNE 1207
S L H + IH +K Y+C +C F
Sbjct: 674 NLSSTLTAH-KKIH----------------------------TGEKPYKCEECGKAFNQS 704
Query: 1208 WDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQ 1267
++ H H ++ ++C+ C ++F+ + L H I H+ E +KC F
Sbjct: 705 SNLTTHKKIHTSEK--PYKCEECGKSFNQFSSLNIHKIIHTGE---KPYKCGDYGRAFNL 759
Query: 1268 ANKLQQH 1274
++ L H
Sbjct: 760 SSNLTTH 766
Score = 111 bits (277), Expect = 5e-24
Identities = 149/690 (21%), Positives = 241/690 (34%), Gaps = 118/690 (17%)
Query: 628 ARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
A P+ + CN+ + + + + H T C +C+K F L +H IH
Sbjct: 70 ATPSKIFQCNKYVKVFDKFSNSNRYKRRH--TGNKHFKCKECSKSFCVLSQLTQHRRIHT 127
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSN 747
+ S Y CE C K F L KH ++C C + F+ + H +
Sbjct: 128 RVNS--YKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIH--T 183
Query: 748 EKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSK 807
E+K +C C F+ + L +H + K +K CG+ F L H+
Sbjct: 184 EEKPNKCEECGKAFKQASHLTIH---KIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTG 240
Query: 808 K--YNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGT--NGASEQVQKEEVELQTLLT 863
+ Y CK C KAF+ L H R K CG N +S ++E++ L
Sbjct: 241 ENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLN 300
Query: 864 NSQESHNSHDGS-----EEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAI 918
+E + + S + + E Y C+ CG + + L H++ I GE
Sbjct: 301 KCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKI----IHTGEKP- 355
Query: 919 VKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHK 978
YKC C + F + L EH + H K Y C CG+ F L H+
Sbjct: 356 -----------YKCKECGKAFNQSSNLTEHKKIHTAE-KSYKCEECGKAFNQHSNLINHR 403
Query: 979 VTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
+S C C H ++H + ++C C + + + L H
Sbjct: 404 KIYSGEKPY-KCEECGKAFNRSSTLTRHKKIHTGEKP----YKCEECDRAFSQSSNLTEH 458
Query: 1039 GTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAG 1095
H TG +K YKC C K F L K + PY C
Sbjct: 459 KKIH------------TG-----EKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYK-CEE 500
Query: 1096 CVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQN 1155
C G+ N S + K+ K + + C +F + +
Sbjct: 501 C----------------------GKAFNQSYQLTRHKIVHTKEKLNKCE-EFGKAFKQSS 537
Query: 1156 HIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVA 1215
H +TIH+ + +K Y+C + VF ++
Sbjct: 538 H-RTIHKII------------------------HTGEKPYKCEEHGKVFNQSSNL---TT 569
Query: 1216 NHMIDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1274
+I G N ++ + + F+ + + H I ++ E KC C + + + L H
Sbjct: 570 QKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEK---PHKCEECGKAYNRFSNLTIH 626
Query: 1275 IFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
G+ K Y C +C + F + L H
Sbjct: 627 KRIHTGE--KPYQCAECGKAFNCSSTLNRH 654
Score = 105 bits (263), Expect = 2e-22
Identities = 78/316 (24%), Positives = 127/316 (40%), Gaps = 41/316 (12%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKI-------NQCQLTDGVDVEDDPTCSWPASSPSSKDQ 96
E + C+ C + F +T HKI N+C+ + K
Sbjct: 493 EKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPY 552
Query: 97 TSPSHGEGCDFGEE-------EGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCT 149
HG+ + G L Y + K+F+ S + +H+ ++ + P KC
Sbjct: 553 KCEEHGKVFNQSSNLTTQKIIHTGENL-YKFEEHGKAFNLFSNITNHKIIYTGEKPHKCE 611
Query: 150 YCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRR 209
C + + + H ++HTG+K Y C+EC AF+ S L H HT KPYKC C +
Sbjct: 612 ECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGK 671
Query: 210 GFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECH 269
F SS+L H ++H K KC +C + F+ +L H + H
Sbjct: 672 AFNLSSTLTAHKKIHTGEKP----------------YKCEECGKAFNQSSNLTTH-KKIH 714
Query: 270 PECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHM 329
P +C C + F + +SL H + +H+GEK C +F+ L +H
Sbjct: 715 TSEKP------YKCEECGKSFNQFSSLNIH-KIIHTGEKPYKCGDYGRAFNLSSNLTTHK 767
Query: 330 DSH--QQPESCNHSNS 343
H ++P C + +
Sbjct: 768 KIHTGEKPYKCEYGKT 783
>gi|7706775 zinc finger protein 107 [Homo sapiens]
Length = 783
Score = 179 bits (453), Expect = 2e-44
Identities = 181/737 (24%), Positives = 282/737 (38%), Gaps = 101/737 (13%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
+ C+ C KSF LS L H + H+ +KC C + F + +H ++HTG+K Y C
Sbjct: 104 FKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCE 163
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERNK 228
EC AF++S L H HT KP KC C + F +S L H +H E K
Sbjct: 164 ECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGK 223
Query: 229 DGSQSGSRMEDWKMKDT----QKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
SQS S + K+ T KC +C + F+ +L H H P +C
Sbjct: 224 VFSQS-SHLTTQKILHTGENLYKCKECGKAFNLFSNLTNH-KRIHAGEKP------YKCK 275
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMD--SHQQPESCNHSN 342
C F +S +N E++H+G K N C C ++F+ +L +H ++P C
Sbjct: 276 ECGRAF-NISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECG 334
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSS-KQA 401
+ S+ T ++ K + +A Q+ ++T A
Sbjct: 335 KV------FNQFSTLT--------RHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTA 380
Query: 402 KVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHE 461
+ +Y C C K F+ + L H K +KP + C+ C + L H K++H
Sbjct: 381 EKSYKCEECGK-AFNQHSNLINHRKIYSGEKP---YKCEECGKAFNRSSTLTRH-KKIHT 435
Query: 462 AQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMG 521
+ P Y+C C + + L EH + G + C C
Sbjct: 436 GEKP-----------YKCEECDRAFSQSSNLTEHKKIHTG--------EKPYKCEECGKA 476
Query: 522 FLTDSSLEEHIRQVH-------CDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSV 574
F S+L +H +++H C+ G F T + V + C F
Sbjct: 477 FNRFSTLTKH-KRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEE---FGKA 532
Query: 575 LKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE- 633
K + H + HK IH G+K V + ++L + + TGE
Sbjct: 533 FKQSSH-RTIHK-------IIHTGEKPYKCEEHGKVFNQSSNLTTQKII------HTGEN 578
Query: 634 -YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITST 692
Y + G + + H + K C +C K + +L H IH
Sbjct: 579 LYKFEEHGKAFNLFSNITNHKIIYTGEKPHK--CEECGKAYNRFSNLTIHKRIH--TGEK 634
Query: 693 YYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVY 752
Y C C K F L +H + ++C C + F+ ++ H + H+ EK Y
Sbjct: 635 PYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKI-HTGEKP-Y 692
Query: 753 RCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYN 810
+C C F ++L H K + K +KC CG+SF L H I T K Y
Sbjct: 693 KCEECGKAFNQSSNLTTHKK---IHTSEKPYKCEECGKSFNQFSSLNIHKIIHTGEKPYK 749
Query: 811 CKFCSKAFHAIILLEKH 827
C +AF+ L H
Sbjct: 750 CGDYGRAFNLSSNLTTH 766
Score = 171 bits (432), Expect = 6e-42
Identities = 186/789 (23%), Positives = 284/789 (35%), Gaps = 138/789 (17%)
Query: 49 CDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFG 108
C C + F LS +T+H+ ++ E +W ++ K + G
Sbjct: 106 CKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHT---------G 156
Query: 109 EEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLH 168
E+ PY C+ C K+F++ S L H+ H+++ P KC C + FK H +H
Sbjct: 157 EK------PYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIH 210
Query: 169 TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNK 228
TG+K Y EC FS+S HL HT YKC C + F S+L H ++H K
Sbjct: 211 TGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEK 270
Query: 229 DGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHE 288
KC +C F+ +L K + H N +C C +
Sbjct: 271 ----------------PYKCKECGRAFNISSNLNKQ-EKIHTGGKLN------KCEECDK 307
Query: 289 LFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSL 346
F L H +++ EK C C + F+ L H H ++P C
Sbjct: 308 AFNRSLKLTAH-KKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECG---- 362
Query: 347 VTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSS-KQAKVTY 405
+ SNL+ + A K +A Q ++ + Y
Sbjct: 363 --------KAFNQSSNLT--EHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPY 412
Query: 406 SCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDP 465
C C K F+ + L H K +KP + C+ C NL EH K++H + P
Sbjct: 413 KCEECGK-AFNRSSTLTRHKKIHTGEKP---YKCEECDRAFSQSSNLTEH-KKIHTGEKP 467
Query: 466 GLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTD 525
Y+C C + N +TL +H R G + C C F
Sbjct: 468 -----------YKCEECGKAFNRFSTLTKHKRIHTG--------EKPYKCEECGKAFNQS 508
Query: 526 SSLEEHIRQVH-------CDLSGSRFGS-------PVLGTPKEPVVEVYSCSYCTNSPIF 571
L H + VH C+ G F ++ T ++P Y C + +F
Sbjct: 509 YQLTRH-KIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKP----YKCE--EHGKVF 561
Query: 572 NSVLKLNK----HIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
N L H EN + +GK S ++ I T K
Sbjct: 562 NQSSNLTTQKIIHTGEN------LYKFEEHGKAFNLFSNITNHKIIYTGEK--------- 606
Query: 628 ARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
+ C +CG Y + H + H T C +C K F +L +H IH
Sbjct: 607 -----PHKCEECGKAYNRFSNLTIHKRIH--TGEKPYQCAECGKAFNCSSTLNRHKIIH- 658
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFVF-FRCTLCQEVFDSKVSIQLHLAVKHS 746
Y C+ C K F L H +HT ++C C + F+ ++ H + H+
Sbjct: 659 -TGEKPYKCKECGKAFNLSSTLTAH-KKIHTGEKPYKCEECGKAFNQSSNLTTHKKI-HT 715
Query: 747 NEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITT 804
+EK Y+C C F + L + H + K +KC G +F L H I T
Sbjct: 716 SEKP-YKCEECGKSFNQFSSLNI---HKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHT 771
Query: 805 HSKKYNCKF 813
K Y C++
Sbjct: 772 GEKPYKCEY 780
Score = 150 bits (380), Expect = 6e-36
Identities = 196/912 (21%), Positives = 310/912 (33%), Gaps = 204/912 (22%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSD-KLPFKCTYCSRLFKHKRSRD--RHIKLHTGDKKY 174
+P Q SF +++ ++ + + + +L C + HK + T K +
Sbjct: 17 WPEQNIKDSFQKVTLRRYGKCEYENLQLRKGCKHVDECTGHKGGHNTVNQCLTATPSKIF 76
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSG 234
C++ F + + + + HT NK +KC C + F S L H ++H R
Sbjct: 77 QCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTR-------- 128
Query: 235 SRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEET 294
++ KC +C + F++ L KH H P +C C + F + +
Sbjct: 129 --------VNSYKCEECGKAFNWFSTLTKH-KRIHTGEKP------YKCEECGKAFNQSS 173
Query: 295 SLMNHMEQVHSGEKKNSCSICSESF------------HTVEELYSHMDSHQQPESCNHSN 342
L H + +H+ EK N C C ++F HT E+ Y + + + +H
Sbjct: 174 QLTRH-KIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLT 232
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
+ ++ G ++ S+ + + + + +++ +KQ K
Sbjct: 233 TQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEK 292
Query: 403 V-----TYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLK 457
+ C C+K SL L H K + +KP + C+ C +V L H K
Sbjct: 293 IHTGGKLNKCEECDKAFNRSLK-LTAHKKILMEEKP---YKCEECGKVFNQFSTLTRH-K 347
Query: 458 QVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPH 517
+H + P Y+C C + N + L EH + ++ C
Sbjct: 348 IIHTGEKP-----------YKCKECGKAFNQSSNLTEHKKIHTA--------EKSYKCEE 388
Query: 518 CYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKL 577
C F S+L H R+++ SG + Y C C + FN L
Sbjct: 389 CGKAFNQHSNLINH-RKIY---SGEK---------------PYKCEECGKA--FNRSSTL 427
Query: 578 NKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICN 637
+H K IH G+K Y C
Sbjct: 428 TRHKK------------IHTGEK--------------------------------PYKCE 443
Query: 638 QCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICE 697
+C ++ + H K H T C +C K F +L KH IH Y CE
Sbjct: 444 ECDRAFSQSSNLTEHKKIH--TGEKPYKCEECGKAFNRFSTLTKHKRIH--TGEKPYKCE 499
Query: 698 SCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSC 757
C K F L +H + +C + F +H + H+ EK Y+C
Sbjct: 500 ECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKII-HTGEKP-YKCEEH 557
Query: 758 NWDFRNETDLQ----LHVKHN--HLENQGKV-------------------HKCIFCGESF 792
F ++L +H N E GK HKC CG+++
Sbjct: 558 GKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAY 617
Query: 793 GTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQ 850
L H I T K Y C C KAF+ L +H K CG
Sbjct: 618 NRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECG------- 670
Query: 851 VQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHN 910
+ L + LT ++ H T E Y C+ CG A+ + L H
Sbjct: 671 ---KAFNLSSTLTAHKKIH-----------TGEKPYKCEECGKAFNQSSNLTTH------ 710
Query: 911 IRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPS 970
KK + YKC C ++F + L H H G K Y C G F
Sbjct: 711 ----------KKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHTGE-KPYKCGDYGRAFNL 759
Query: 971 LLTLTEHKVTHS 982
LT HK H+
Sbjct: 760 SSNLTTHKKIHT 771
Score = 138 bits (347), Expect = 4e-32
Identities = 132/573 (23%), Positives = 217/573 (37%), Gaps = 111/573 (19%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGE 103
E ++ C C + F S++T HK ++ G C + S+ ++ H
Sbjct: 241 ENLYKCKECGKAFNLFSNLTNHK----RIHAGEKPYKCKECGRAFNISSNLNKQEKIHTG 296
Query: 104 G----CDFGEEEGGPGL-------------PYPCQFCDKSFSRLSYLKHHEQSHSDKLPF 146
G C+ ++ L PY C+ C K F++ S L H+ H+ + P+
Sbjct: 297 GKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPY 356
Query: 147 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAI 206
KC C + F + H K+HT +K Y C EC AF++ +L H K ++ KPYKC
Sbjct: 357 KCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEE 416
Query: 207 CRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIA 266
C + F SS+L H ++H K KC +C+ F +L +H
Sbjct: 417 CGKAFNRSSTLTRHKKIHTGEK----------------PYKCEECDRAFSQSSNLTEH-K 459
Query: 267 ECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESF------- 319
+ H P +C C + F ++L H +++H+GEK C C ++F
Sbjct: 460 KIHTGEKP------YKCEECGKAFNRFSTLTKH-KRIHTGEKPYKCEECGKAFNQSYQLT 512
Query: 320 -----HTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSST------TPDSNLSVDSS 368
HT E+L + + + +H ++ G SNL+ +
Sbjct: 513 RHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLT--TQ 570
Query: 369 TMVEAAPPIPKSRGRKRAAQQTPDMTGPS-SKQAKVTYSCIYCNKQLFSSLAVLQIHLKT 427
++ + K +A ++T + + C C K ++ + L IH +
Sbjct: 571 KIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGK-AYNRFSNLTIHKRI 629
Query: 428 MHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVN 487
+KP Q C C + LN H K +H + P Y+C C + N
Sbjct: 630 HTGEKPYQ---CAECGKAFNCSSTLNRH-KIIHTGEKP-----------YKCKECGKAFN 674
Query: 488 DLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSP 547
+TL H + G + C C F S+L H +++H
Sbjct: 675 LSSTLTAHKKIHTG--------EKPYKCEECGKAFNQSSNLTTH-KKIH----------- 714
Query: 548 VLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKH 580
T ++P Y C C S FN LN H
Sbjct: 715 ---TSEKP----YKCEECGKS--FNQFSSLNIH 738
Score = 134 bits (338), Expect = 4e-31
Identities = 178/847 (21%), Positives = 293/847 (34%), Gaps = 189/847 (22%)
Query: 469 VSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSL 528
++A P+ ++QCN +V + + + R G + F C C F S L
Sbjct: 68 LTATPSKIFQCNKYVKVFDKFSNSNRYKRRHTG--------NKHFKCKECSKSFCVLSQL 119
Query: 529 EEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNI 588
+H R++H ++ Y C C + FN L KH +
Sbjct: 120 TQH-RRIHTRVNS------------------YKCEECGKA--FNWFSTLTKHKR------ 152
Query: 589 PLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDS 648
IH G+K Y C +CG +
Sbjct: 153 ------IHTGEKP--------------------------------YKCEECGKAFNQSSQ 174
Query: 649 FQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDD 708
H H + K C +C K F L H IH Y E C K F+
Sbjct: 175 LTRHKIIHTEEKPNK--CEECGKAFKQASHLTIHKIIH--TGEKPYKYEECGKVFSQSSH 230
Query: 709 LQKHLLDMHTFV-FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDL 767
L + +HT ++C C + F+ ++ H + H+ EK Y+C C F ++L
Sbjct: 231 LTTQKI-LHTGENLYKCKECGKAFNLFSNLTNHKRI-HAGEKP-YKCKECGRAFNISSNL 287
Query: 768 QLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLE 825
K + GK++KC C ++F ++L H I K Y C+ C K F+ L
Sbjct: 288 N---KQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLT 344
Query: 826 KHLREKHCVFETKTPNCGT--NGASEQVQKEEVELQTLLTNSQE---SHNSHDG--SEED 878
+H K CG N +S + +++ +E + N H +
Sbjct: 345 RHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRK 404
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRP------------GESAIVKKKAELI 926
+ + E Y C+ CG A+ + L H+ +P + KK
Sbjct: 405 IYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTG 464
Query: 927 KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKS-- 984
+ YKC C + F + L +H + H G K Y C CG+ F LT HK+ H+K
Sbjct: 465 EKPYKCEECGKAFNRFSTLTKHKRIHTGE-KPYKCEECGKAFNQSYQLTRHKIVHTKEKL 523
Query: 985 ----------LDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLE 1034
+ + I K+ E+ + C+ H + N + + T + +
Sbjct: 524 NKCEEFGKAFKQSSHRTIHKIIHTGEKPY--KCEEHGKVFNQSSNLTTQKIIHTGENLYK 581
Query: 1035 LKIHG-TFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPY 1090
+ HG F++ + TG +K +KC C K + +L ++ PY
Sbjct: 582 FEEHGKAFNLFSNITNHKIIYTG-----EKPHKCEECGKAYNRFSNLTIHKRIHTGEKPY 636
Query: 1091 GLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKV---GGLKTRCSSCNVKF 1147
CA C G+ N S+ + K+ G +C C F
Sbjct: 637 -QCAEC----------------------GKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 673
Query: 1148 ESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNE 1207
S L H + IH +K Y+C +C F
Sbjct: 674 NLSSTLTAH-KKIH----------------------------TGEKPYKCEECGKAFNQS 704
Query: 1208 WDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQ 1267
++ H H ++ ++C+ C ++F+ + L H I H+ E +KC F
Sbjct: 705 SNLTTHKKIHTSEK--PYKCEECGKSFNQFSSLNIHKIIHTGE---KPYKCGDYGRAFNL 759
Query: 1268 ANKLQQH 1274
++ L H
Sbjct: 760 SSNLTTH 766
Score = 111 bits (277), Expect = 5e-24
Identities = 149/690 (21%), Positives = 241/690 (34%), Gaps = 118/690 (17%)
Query: 628 ARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHF 687
A P+ + CN+ + + + + H T C +C+K F L +H IH
Sbjct: 70 ATPSKIFQCNKYVKVFDKFSNSNRYKRRH--TGNKHFKCKECSKSFCVLSQLTQHRRIHT 127
Query: 688 MITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSN 747
+ S Y CE C K F L KH ++C C + F+ + H +
Sbjct: 128 RVNS--YKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIH--T 183
Query: 748 EKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSK 807
E+K +C C F+ + L +H + K +K CG+ F L H+
Sbjct: 184 EEKPNKCEECGKAFKQASHLTIH---KIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTG 240
Query: 808 K--YNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGT--NGASEQVQKEEVELQTLLT 863
+ Y CK C KAF+ L H R K CG N +S ++E++ L
Sbjct: 241 ENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLN 300
Query: 864 NSQESHNSHDGS-----EEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAI 918
+E + + S + + E Y C+ CG + + L H++ I GE
Sbjct: 301 KCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKI----IHTGEKP- 355
Query: 919 VKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHK 978
YKC C + F + L EH + H K Y C CG+ F L H+
Sbjct: 356 -----------YKCKECGKAFNQSSNLTEHKKIHTAE-KSYKCEECGKAFNQHSNLINHR 403
Query: 979 VTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
+S C C H ++H + ++C C + + + L H
Sbjct: 404 KIYSGEKPY-KCEECGKAFNRSSTLTRHKKIHTGEKP----YKCEECDRAFSQSSNLTEH 458
Query: 1039 GTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK---LDINGLPYGLCAG 1095
H TG +K YKC C K F L K + PY C
Sbjct: 459 KKIH------------TG-----EKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYK-CEE 500
Query: 1096 CVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQN 1155
C G+ N S + K+ K + + C +F + +
Sbjct: 501 C----------------------GKAFNQSYQLTRHKIVHTKEKLNKCE-EFGKAFKQSS 537
Query: 1156 HIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVA 1215
H +TIH+ + +K Y+C + VF ++
Sbjct: 538 H-RTIHKII------------------------HTGEKPYKCEEHGKVFNQSSNL---TT 569
Query: 1216 NHMIDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1274
+I G N ++ + + F+ + + H I ++ E KC C + + + L H
Sbjct: 570 QKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEK---PHKCEECGKAYNRFSNLTIH 626
Query: 1275 IFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
G+ K Y C +C + F + L H
Sbjct: 627 KRIHTGE--KPYQCAECGKAFNCSSTLNRH 654
Score = 105 bits (263), Expect = 2e-22
Identities = 78/316 (24%), Positives = 127/316 (40%), Gaps = 41/316 (12%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKI-------NQCQLTDGVDVEDDPTCSWPASSPSSKDQ 96
E + C+ C + F +T HKI N+C+ + K
Sbjct: 493 EKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPY 552
Query: 97 TSPSHGEGCDFGEE-------EGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCT 149
HG+ + G L Y + K+F+ S + +H+ ++ + P KC
Sbjct: 553 KCEEHGKVFNQSSNLTTQKIIHTGENL-YKFEEHGKAFNLFSNITNHKIIYTGEKPHKCE 611
Query: 150 YCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRR 209
C + + + H ++HTG+K Y C+EC AF+ S L H HT KPYKC C +
Sbjct: 612 ECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGK 671
Query: 210 GFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECH 269
F SS+L H ++H K KC +C + F+ +L H + H
Sbjct: 672 AFNLSSTLTAHKKIHTGEKP----------------YKCEECGKAFNQSSNLTTH-KKIH 714
Query: 270 PECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHM 329
P +C C + F + +SL H + +H+GEK C +F+ L +H
Sbjct: 715 TSEKP------YKCEECGKSFNQFSSLNIH-KIIHTGEKPYKCGDYGRAFNLSSNLTTHK 767
Query: 330 DSH--QQPESCNHSNS 343
H ++P C + +
Sbjct: 768 KIHTGEKPYKCEYGKT 783
>gi|222831664 zinc finger protein 184 [Homo sapiens]
Length = 751
Score = 177 bits (448), Expect = 8e-44
Identities = 158/662 (23%), Positives = 235/662 (35%), Gaps = 152/662 (22%)
Query: 120 CQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSEC 179
C C K+FS S L H+++H+ + P+KC C + F + H ++HTGDK Y C +C
Sbjct: 224 CNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQC 283
Query: 180 DAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMED 239
F L H + HT KPYKC C + F + L H ++H K
Sbjct: 284 GKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEK----------- 332
Query: 240 WKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNH 299
C++C + F +H + H P +C C + F T L H
Sbjct: 333 -----PYTCNECGKAFSQRGHFMEH-QKIHTGEKP------FKCDECDKTFTRSTHLTQH 380
Query: 300 MEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSST 357
+++H+GEK C+ C ++F+ H H ++P CN +
Sbjct: 381 -QKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECG------------KAF 427
Query: 358 TPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSS 417
+ SNL+ T P Y C C K FS
Sbjct: 428 SQHSNLTQHQKTHTGEKP-----------------------------YDCAECGKS-FSY 457
Query: 418 LAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVY 477
+ L HLK +KP + C C + +L +H +++H + P +
Sbjct: 458 WSSLAQHLKIHTGEKP---YKCNECGKAFSYCSSLTQH-RRIHTREKP-----------F 502
Query: 478 QCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIR---- 533
+C+ C + + L+ L +H A+ C C F+ SSL +H R
Sbjct: 503 ECSECGKAFSYLSNLNQH--------QKTHTQEKAYECKECGKAFIRSSSLAKHERIHTG 554
Query: 534 --QVHCDLSGSRF--GSPVLGTPKEPVVE-VYSCSYCTNSPIFNSVLKLNKHIKENHKNI 588
C G F GS ++ K E Y C+ C + FN + L +H +
Sbjct: 555 EKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRA--FNQNIHLTQHKR------ 606
Query: 589 PLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDS 648
IH G K Y C +CG + S
Sbjct: 607 ------IHTGAK--------------------------------PYECAECGKAFRHCSS 628
Query: 649 FQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDD 708
H KTH T C +C K F L +H IH Y C CDK F+
Sbjct: 629 LAQHQKTH--TEEKPYQCNKCEKTFSQSSHLTQHQRIH--TGEKPYKCNECDKAFSRSTH 684
Query: 709 LQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQ 768
L +H + C C++ F + H + HS EK + C C FR + L
Sbjct: 685 LTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRI-HSGEKP-FGCNDCGKSFRYRSALN 742
Query: 769 LH 770
H
Sbjct: 743 KH 744
Score = 164 bits (414), Expect = 7e-40
Identities = 149/610 (24%), Positives = 228/610 (37%), Gaps = 128/610 (20%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C+K+FSR L +H++ H+ P+KC C + F S +H ++HTG+K Y C
Sbjct: 249 PYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKC 308
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH---------ERN 227
EC AFS+ HL H + HT KPY C C + F H ++H E +
Sbjct: 309 DECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECD 368
Query: 228 KDGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCV 284
K ++S + K+ + T KC++C + F+ P +H H P E C
Sbjct: 369 KTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRH-HMIHTGEKPYE------CN 421
Query: 285 YCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSN 342
C + F + ++L H ++ H+GEK C+ C +SF L H+ H ++P CN
Sbjct: 422 ECGKAFSQHSNLTQH-QKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECG 480
Query: 343 SPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAK 402
++ SS T + P S K + + + +
Sbjct: 481 K------AFSYCSSLTQHRRIHTREK-------PFECSECGKAFSYLSNLNQHQKTHTQE 527
Query: 403 VTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEA 462
Y C C K S ++ + H + +KP Q H C SL +H +++H
Sbjct: 528 KAYECKECGKAFIRSSSLAK-HERIHTGEKPYQCHECGKTFSYGSSLI---QH-RKIHTG 582
Query: 463 QDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGF 522
+ P Y+CN C N L +H R G + + C C F
Sbjct: 583 ERP-----------YKCNECGRAFNQNIHLTQHKRIHTG--------AKPYECAECGKAF 623
Query: 523 LTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIK 582
SSL +H ++ H T ++P Y C+ C + F+ L +H +
Sbjct: 624 RHCSSLAQH-QKTH--------------TEEKP----YQCNKCEKT--FSQSSHLTQHQR 662
Query: 583 ENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAK 642
IH G+K Y CN+C
Sbjct: 663 ------------IHTGEK--------------------------------PYKCNECDKA 678
Query: 643 YTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQ 702
++ H TH T C +C K F L++H IH + C C K
Sbjct: 679 FSRSTHLTEHQNTH--TGEKPYNCNECRKTFSQSTYLIQHQRIH--SGEKPFGCNDCGKS 734
Query: 703 FTSVDDLQKH 712
F L KH
Sbjct: 735 FRYRSALNKH 744
Score = 159 bits (401), Expect = 2e-38
Identities = 162/678 (23%), Positives = 248/678 (36%), Gaps = 143/678 (21%)
Query: 158 KRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSL 217
KRS ++ +K C+EC AFS L H +THT KPYKC C + F S +L
Sbjct: 206 KRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENL 265
Query: 218 HGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNED 277
H ++H +K KC QC +GF L +H H P
Sbjct: 266 INHQRIHTGDK----------------PYKCDQCGKGFIEGPSLTQH-QRIHTGEKP--- 305
Query: 278 RAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQP 335
+C C + F + T L+ H +++H+GEK +C+ C ++F H H ++P
Sbjct: 306 ---YKCDECGKAFSQRTHLVQH-QRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKP 361
Query: 336 ESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTG 395
C+ + T ST Q TG
Sbjct: 362 FKCDECDK--------TFTRST---------------------------HLTQHQKIHTG 386
Query: 396 PSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEH 455
+ TY C C K ++ H+ + E+ + C C + NL +H
Sbjct: 387 ------EKTYKCNECGKAFNGPSTFIRHHM----IHTGEKPYECNECGKAFSQHSNLTQH 436
Query: 456 LKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFC 515
K H + P Y C C + + ++L +H++ G + C
Sbjct: 437 QK-THTGEKP-----------YDCAECGKSFSYWSSLAQHLKIHTG--------EKPYKC 476
Query: 516 PHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVL 575
C F SSL +H R++H T ++P + CS C + F+ +
Sbjct: 477 NECGKAFSYCSSLTQH-RRIH--------------TREKP----FECSECGKA--FSYLS 515
Query: 576 KLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE-- 633
LN+H K H +K+ I +SL + + TGE
Sbjct: 516 NLNQHQK------------THTQEKAYECKECGKAFIRSSSLAKHERI------HTGEKP 557
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y C++CG ++ S H K H T C +C + F L +H IH +
Sbjct: 558 YQCHECGKTFSYGSSLIQHRKIH--TGERPYKCNECGRAFNQNIHLTQHKRIH--TGAKP 613
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y C C K F L +H ++C C++ F + H + H+ EK Y+
Sbjct: 614 YECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRI-HTGEKP-YK 671
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNC 811
C C+ F T L +H + K + C C ++F L H HS K + C
Sbjct: 672 CNECDKAFSRSTHL---TEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGC 728
Query: 812 KFCSKAFHAIILLEKHLR 829
C K+F L KH R
Sbjct: 729 NDCGKSFRYRSALNKHQR 746
Score = 157 bits (396), Expect = 8e-38
Identities = 132/523 (25%), Positives = 211/523 (40%), Gaps = 79/523 (15%)
Query: 25 DGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTC 84
+G +L +R GE+ + CD C + F + + +H+ ++ G E TC
Sbjct: 289 EGPSLTQHQRIHTGEK-----PYKCDECGKAFSQRTHLVQHQ----RIHTG---EKPYTC 336
Query: 85 SWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKL 144
+ + S + + GE+ P+ C CDK+F+R ++L H++ H+ +
Sbjct: 337 NECGKAFSQRGHFMEH--QKIHTGEK------PFKCDECDKTFTRSTHLTQHQKIHTGEK 388
Query: 145 PFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKC 204
+KC C + F + RH +HTG+K Y C+EC AFS+ +L H KTHT KPY C
Sbjct: 389 TYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDC 448
Query: 205 AICRRGFLSSSSLHGHMQVH---------ERNKDGSQSGSRMEDWKMKDTQK---CSQCE 252
A C + F SSL H+++H E K S S + ++ +K CS+C
Sbjct: 449 AECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECG 508
Query: 253 EGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSC 312
+ F + +L +H + H + A +C C + F+ +SL H E++H+GEK C
Sbjct: 509 KAFSYLSNLNQH-QKTHTQ------EKAYECKECGKAFIRSSSLAKH-ERIHTGEKPYQC 560
Query: 313 SICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTM 370
C ++F L H H ++P CN + T +
Sbjct: 561 HECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLT-------------QHKRI 607
Query: 371 VEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHL 430
A P + K + + + Y C C K FS + L H +
Sbjct: 608 HTGAKPYECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEK-TFSQSSHLTQHQRIHTG 666
Query: 431 DKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLN 490
+KP + C C + +L EH + H + P Y CN C + +
Sbjct: 667 EKP---YKCNECDKAFSRSTHLTEH-QNTHTGEKP-----------YNCNECRKTFSQST 711
Query: 491 TLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIR 533
L +H R G F C C F S+L +H R
Sbjct: 712 YLIQHQRIHSG--------EKPFGCNDCGKSFRYRSALNKHQR 746
Score = 145 bits (366), Expect = 2e-34
Identities = 159/643 (24%), Positives = 239/643 (37%), Gaps = 105/643 (16%)
Query: 364 SVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQI 423
SV+ S+ + P P+ KR+ +Q + P K+ C C K FS + L
Sbjct: 186 SVNVSSNLVTQEPSPEETSTKRSIKQN---SNPVKKEKSC--KCNECGKA-FSYCSALIR 239
Query: 424 HLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCS 483
H +T +KP + C C + NL H +++H P Y+C+ C
Sbjct: 240 HQRTHTGEKPYK---CNECEKAFSRSENLINH-QRIHTGDKP-----------YKCDQCG 284
Query: 484 EVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVH------- 536
+ + +L +H R G + C C F + L +H R +H
Sbjct: 285 KGFIEGPSLTQHQRIHTG--------EKPYKCDECGKAFSQRTHLVQHQR-IHTGEKPYT 335
Query: 537 CDLSGSRFGS-------PVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIP 589
C+ G F + T ++P + C C + F L +H K
Sbjct: 336 CNECGKAFSQRGHFMEHQKIHTGEKP----FKCDECDKT--FTRSTHLTQHQK------- 382
Query: 590 LALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLD 647
IH G+K+ + ++ + TGE Y CN+CG ++
Sbjct: 383 -----IHTGEKTYKCNECGKAFNGPSTFIRHHMIH------TGEKPYECNECGKAFSQHS 431
Query: 648 SFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVD 707
+ H KTH T C +C K F SL +H+ IH Y C C K F+
Sbjct: 432 NLTQHQKTH--TGEKPYDCAECGKSFSYWSSLAQHLKIH--TGEKPYKCNECGKAFSYCS 487
Query: 708 DLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDL 767
L +H F C+ C + F ++ H K ++K Y C C F + L
Sbjct: 488 SLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQ--KTHTQEKAYECKECGKAFIRSSSL 545
Query: 768 QLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLE 825
KH + K ++C CG++F L H I T + Y C C +AF+ I L
Sbjct: 546 ---AKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLT 602
Query: 826 KHLREKHCVFETKTPNCGTN----GASEQVQKEEVELQTLLTNSQE---SHNSHDGSEED 878
+H R + CG + Q QK E + N E S +SH +
Sbjct: 603 QHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQR 662
Query: 879 VDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRT 938
+ T E Y C+ C A++ T L HQ N GE Y CN C +T
Sbjct: 663 IHTGEKPYKCNECDKAFSRSTHLTEHQ----NTHTGEKP------------YNCNECRKT 706
Query: 939 FFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTH 981
F L +H + H G K + C CG+ F L +H+ H
Sbjct: 707 FSQSTYLIQHQRIHSGE-KPFGCNDCGKSFRYRSALNKHQRLH 748
Score = 138 bits (348), Expect = 3e-32
Identities = 164/708 (23%), Positives = 243/708 (34%), Gaps = 132/708 (18%)
Query: 577 LNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAI-----EQTSLKMMQAVGGAPARPT 631
L K IK K IP N + ++++ S + E+TS K P +
Sbjct: 160 LPKEIKVTEKTIPSWEKGPVNNEFGKSVNVSSNLVTQEPSPEETSTKRSIKQNSNPVKKE 219
Query: 632 GEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITS 691
CN+CG ++ + H +TH T C +C K F E+L+ H IH
Sbjct: 220 KSCKCNECGKAFSYCSALIRHQRTH--TGEKPYKCNECEKAFSRSENLINHQRIH--TGD 275
Query: 692 TYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKV 751
Y C+ C K F L +H ++C C + F + + H + H+ EK
Sbjct: 276 KPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRI-HTGEKP- 333
Query: 752 YRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCH--ITTHSKKY 809
Y C C F ++H + K KC C ++F L H I T K Y
Sbjct: 334 YTCNECGKAFSQRGHF---MEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTY 390
Query: 810 NCKFCSKAFHAIILLEKHLREKHCVFETKTP-NCGTNGASEQVQKEEVELQTLLTNSQES 868
C C KAF+ +H H + + P C G + + LT Q++
Sbjct: 391 KCNECGKAFNGPSTFIRH----HMIHTGEKPYECNECG-------KAFSQHSNLTQHQKT 439
Query: 869 HNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKG 928
H T E Y C CG +++ + L H I GE
Sbjct: 440 H-----------TGEKPYDCAECGKSFSYWSSLAQHL----KIHTGEKP----------- 473
Query: 929 NYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTG 988
YKCN C + F + L +H + H K + C CG+ F L L +H+ TH++
Sbjct: 474 -YKCNECGKAFSYCSSLTQHRRIHTRE-KPFECSECGKAFSYLSNLNQHQKTHTQE-KAY 530
Query: 989 NCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGN 1048
C+ C +H ++H + ++C C +T + L H H TG
Sbjct: 531 ECKECGKAFIRSSSLAKHERIHTGEK----PYQCHECGKTFSYGSSLIQHRKIH---TG- 582
Query: 1049 GSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASP 1105
++ YKC C + F L ++ PY CA C + S
Sbjct: 583 -------------ERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYE-CAECGKAFRHCS- 627
Query: 1106 GINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELV 1165
L Q++ E +C+ C F S L H Q IH
Sbjct: 628 -----------SLAQHQKTHTEE-------KPYQCNKCEKTFSQSSHLTQH-QRIH---- 664
Query: 1166 PDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNH 1225
+K Y+C +C F + H H ++ N
Sbjct: 665 ------------------------TGEKPYKCNECDKAFSRSTHLTEHQNTHTGEKPYN- 699
Query: 1226 ECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQ 1273
C C +TF L H HS E G C F NK Q+
Sbjct: 700 -CNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQR 746
Score = 135 bits (341), Expect = 2e-31
Identities = 87/305 (28%), Positives = 137/305 (44%), Gaps = 43/305 (14%)
Query: 44 EAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDP----TCSWPASSPSSKDQTSP 99
E + C+ C + F S +T+H+ + + P C S S+ +Q
Sbjct: 471 EKPYKCNECGKAFSYCSSLTQHR--------RIHTREKPFECSECGKAFSYLSNLNQHQK 522
Query: 100 SHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKR 159
+H + Y C+ C K+F R S L HE+ H+ + P++C C + F +
Sbjct: 523 THTQE-----------KAYECKECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGS 571
Query: 160 SRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHG 219
S +H K+HTG++ Y C+EC AF+++ HL H + HT KPY+CA C + F SSL
Sbjct: 572 SLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQ 631
Query: 220 HMQVHER---------NKDGSQSGSRMEDWKM---KDTQKCSQCEEGFDFPEDLQKHIAE 267
H + H K SQS + ++ + KC++C++ F L +H
Sbjct: 632 HQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEH-QN 690
Query: 268 CHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYS 327
H P C C + F + T L+ H +++HSGEK C+ C +SF L
Sbjct: 691 THTGEKP------YNCNECRKTFSQSTYLIQH-QRIHSGEKPFGCNDCGKSFRYRSALNK 743
Query: 328 HMDSH 332
H H
Sbjct: 744 HQRLH 748
Score = 124 bits (311), Expect = 6e-28
Identities = 146/644 (22%), Positives = 215/644 (33%), Gaps = 156/644 (24%)
Query: 666 CPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCT 725
C +C K F +L++H H Y C C+K F+ ++L H ++C
Sbjct: 224 CNECGKAFSYCSALIRHQRTH--TGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCD 281
Query: 726 LCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKC 785
C + F S+ H + H+ EK Y+C C F T L V+H + K + C
Sbjct: 282 QCGKGFIEGPSLTQHQRI-HTGEKP-YKCDECGKAFSQRTHL---VQHQRIHTGEKPYTC 336
Query: 786 IFCGESFGTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG 843
CG++F H I T K + C C K F R H
Sbjct: 337 NECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKTF---------TRSTH----------- 376
Query: 844 TNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQN 903
LT Q+ H T E Y C+ CG A+ +
Sbjct: 377 ------------------LTQHQKIH-----------TGEKTYKCNECGKAFNGPSTF-- 405
Query: 904 HQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPI 963
+R H I GE Y+CN C + F + L +H +TH G K Y C
Sbjct: 406 --IRHHMIHTGEKP------------YECNECGKAFSQHSNLTQHQKTHTGE-KPYDCAE 450
Query: 964 CGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCV 1023
CG+ F +L +H H+ C C +H ++H + F C
Sbjct: 451 CGKSFSYWSSLAQHLKIHTGEKPY-KCNECGKAFSYCSSLTQHRRIHTREKP----FECS 505
Query: 1024 VCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK- 1082
C + + L H H Q +K Y+C C K F L K
Sbjct: 506 ECGKAFSYLSNLNQHQKTHTQ-----------------EKAYECKECGKAFIRSSSLAKH 548
Query: 1083 --LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRC 1140
+ PY C K+ S G + L Q+ + G +C
Sbjct: 549 ERIHTGEKPYQ----CHECGKTFSYGSS---------LIQHRKIHT-------GERPYKC 588
Query: 1141 SSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKC 1200
+ C F L H + IH P Y+C +C
Sbjct: 589 NECGRAFNQNIHLTQH-KRIHTGAKP----------------------------YECAEC 619
Query: 1201 QMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPV 1260
F + + H H E ++C C +TF + L H H+ E +KC
Sbjct: 620 GKAFRHCSSLAQHQKTHT--EEKPYQCNKCEKTFSQSSHLTQHQRIHTGEK---PYKCNE 674
Query: 1261 CFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C F ++ L +H + G+ K Y+C +C + F T L H
Sbjct: 675 CDKAFSRSTHLTEHQNTHTGE--KPYNCNECRKTFSQSTYLIQH 716
Score = 116 bits (290), Expect = 2e-25
Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 17/154 (11%)
Query: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 176
PY C C K+F S L H+++H+++ P++C C + F +H ++HTG+K Y C
Sbjct: 613 PYECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKC 672
Query: 177 SECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSR 236
+ECD AFSRS HL H THT KPY C CR+ F S+ L H ++H K
Sbjct: 673 NECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFG----- 727
Query: 237 MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHP 270
C+ C + F + L KH HP
Sbjct: 728 -----------CNDCGKSFRYRSALNKH-QRLHP 749
Score = 107 bits (267), Expect = 7e-23
Identities = 145/579 (25%), Positives = 198/579 (34%), Gaps = 124/579 (21%)
Query: 764 ETDLQLHVKHN-HLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHA 820
ET + +K N + + K KC CG++F L H TH+ K Y C C KAF
Sbjct: 202 ETSTKRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSR 261
Query: 821 IILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVD 880
L H R K CG K +E +L T Q H
Sbjct: 262 SENLINHQRIHTGDKPYKCDQCG---------KGFIEGPSL-TQHQRIH----------- 300
Query: 881 TSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFF 940
T E Y CD CG A++ T L HQ I GE Y CN C + F
Sbjct: 301 TGEKPYKCDECGKAFSQRTHLVQHQ----RIHTGEKP------------YTCNECGKAFS 344
Query: 941 SENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSE 1000
EH + H G K + C C + F LT+H+ H+ T C C
Sbjct: 345 QRGHFMEHQKIHTGE-KPFKCDECDKTFTRSTHLTQHQKIHTGE-KTYKCNECGKAFNGP 402
Query: 1001 EEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQH 1060
F+ H +H + + C C + + L H QKT G
Sbjct: 403 STFIRHHMIHTGEKP----YECNECGKAFSQHSNLTQH-----QKTHTG----------- 442
Query: 1061 VQKLYKCASCLKEFRSKQDL---VKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPG 1117
+K Y CA C K F L +K+ PY C C S
Sbjct: 443 -EKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYK-CNECGKAFSYCS------------S 488
Query: 1118 LGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELV---PDSNSTQLK 1174
L Q+ + E + CS C F S L H +T +E + ++
Sbjct: 489 LTQHRRIHTREKPFE-------CSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIR 541
Query: 1175 TPQVSPMPRISPSQSDEKKTYQCIKCQMVF-YNEWDIQ---------------------- 1211
+ ++ RI + K YQC +C F Y IQ
Sbjct: 542 SSSLAKHERIHTGE----KPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQ 597
Query: 1212 -VHVANHM-IDEGLN-HECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQA 1268
+H+ H I G +EC C + F + L H H+ E ++C C F Q+
Sbjct: 598 NIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHTEEK---PYQCNKCEKTFSQS 654
Query: 1269 NKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMT 1307
+ L QH G+ K Y C +C + F T L H T
Sbjct: 655 SHLTQHQRIHTGE--KPYKCNECDKAFSRSTHLTEHQNT 691
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/140 (25%), Positives = 64/140 (45%), Gaps = 15/140 (10%)
Query: 31 CKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASS 90
C + + +E + C+ C + F S +T+H+ ++ G C S
Sbjct: 626 CSSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQ----RIHTGEKPYKCNECDKAFSR 681
Query: 91 PSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTY 150
+ + +H GE+ PY C C K+FS+ +YL H++ HS + PF C
Sbjct: 682 STHLTEHQNTHT-----GEK------PYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCND 730
Query: 151 CSRLFKHKRSRDRHIKLHTG 170
C + F+++ + ++H +LH G
Sbjct: 731 CGKSFRYRSALNKHQRLHPG 750
>gi|150378520 zinc finger protein 594 [Homo sapiens]
Length = 807
Score = 177 bits (448), Expect = 8e-44
Identities = 173/751 (23%), Positives = 275/751 (36%), Gaps = 139/751 (18%)
Query: 118 YPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCS 177
Y C+ C+K+F+R S L H++ H+ P+ C C + + H ++HTG K Y C
Sbjct: 127 YECKECEKTFNRSSNLIIHQRIHTGNKPYVCNECGKDSNQSSNLIIHQRIHTGKKPYICH 186
Query: 178 ECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRM 237
EC F++S +L H + H+ PY+C C + F SS+L H ++H R K
Sbjct: 187 ECGKDFNQSSNLVRHKQIHSGGNPYECKECGKAFKGSSNLVLHQRIHSRGK--------- 237
Query: 238 EDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLM 297
C++C + F DL H H P E C C ++F + + L+
Sbjct: 238 -------PYLCNKCGKAFSQSTDLIIH-HRIHTGEKPYE------CYDCGQMFSQSSHLV 283
Query: 298 NHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCNHSNSPSLVTVGYTSVS 355
H +++H+GEK C+ C ++F L H H ++P C+ +
Sbjct: 284 PH-QRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRTAFLKHQ 342
Query: 356 STTPDSNLSVDSSTMVEAAPPIPKSRGRK-----------RAAQQTPDMTGPS-SKQAKV 403
+ T + + R + R Q T D+ + +
Sbjct: 343 RLHAGEKIEECEKTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHTGEK 402
Query: 404 TYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQ 463
Y C C K S +L+ H + E+ +C C + +L H +VH +
Sbjct: 403 PYECKECGKTFNQSSDLLRHH----RIHSGEKPCVCSKCGKSFRGSSDLIRH-HRVHTGE 457
Query: 464 DPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFL 523
P Y+C+ C + + + L H + G + C C F
Sbjct: 458 KP-----------YECSECGKAFSQRSHLVTHQKIHTG--------EKPYQCTECGKAFR 498
Query: 524 TDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKE 583
S L +H R++H SG + Y C C I+ +
Sbjct: 499 RRSLLIQH-RRIH---SGEK---------------PYECKECGKLFIWRTAF-------- 531
Query: 584 NHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKY 643
L +H G+K S + L+ Q + + Y CNQCG +
Sbjct: 532 ------LKHQSLHTGEKLECEKTFS----QDEELRGEQKI----HQEAKAYWCNQCGRAF 577
Query: 644 TSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQF 703
H TH T C +C K F LL+H IH Y+C C K F
Sbjct: 578 QGSSDLIRHQVTH--TREKPYECKECGKTFNQSSDLLRHHRIH--SGEKPYVCNKCGKSF 633
Query: 704 TSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRN 763
DL KH + C+ C + F + + H + H+ EK Y+C+ C FR
Sbjct: 634 RGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATHQKI-HTGEKP-YQCSECGNAFRR 691
Query: 764 ETDLQLHVKHNHLENQGKVHKCIFCG-------------------------ESFGTEVEL 798
+ L ++H L + K ++C CG ++F + EL
Sbjct: 692 RS---LLIQHRRLHSGEKPYECKECGKLFMWHTAFLKHQRLHAGEKLEECEKTFSKDEEL 748
Query: 799 QCHITTHSKK--YNCKFCSKAFHAIILLEKH 827
+ TH +K Y C CS+ F L +H
Sbjct: 749 RKEQRTHQEKKVYWCNQCSRTFQGSSDLIRH 779
Score = 165 bits (417), Expect = 3e-40
Identities = 168/705 (23%), Positives = 261/705 (37%), Gaps = 143/705 (20%)
Query: 115 GLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 174
G PY C+ C K+F S L H++ HS P+ C C + F H ++HTG+K Y
Sbjct: 208 GNPYECKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPY 267
Query: 175 HCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVH------ERNK 228
C +C FS+S HL H + HT KP KC C + F S L H ++H E ++
Sbjct: 268 ECYDCGQMFSQSSHLVPHQRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHR 327
Query: 229 DGSQSGSR---MEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVY 285
G R ++ ++ +K +CE+ F E+L++ E +++ A C
Sbjct: 328 CGKTFSGRTAFLKHQRLHAGEKIEECEKTFSKDEELRE-------EQRIHQEEKAYWCNQ 380
Query: 286 CHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPS 345
C F + L+ H + H+GEK C C ++F+ +L H H + C S
Sbjct: 381 CGRNFQGTSDLIRH-QVTHTGEKPYECKECGKTFNQSSDLLRHHRIHSGEKPCVCSKCGK 439
Query: 346 LVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTY 405
RG + TG + Y
Sbjct: 440 ---------------------------------SFRGSSDLIRHHRVHTG------EKPY 460
Query: 406 SCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDP 465
C C K FS + L H K +KP Q C C + L +H +++H + P
Sbjct: 461 ECSECGK-AFSQRSHLVTHQKIHTGEKPYQ---CTECGKAFRRRSLLIQH-RRIHSGEKP 515
Query: 466 GLIVSAMPAIVYQCNFCSEVV---------NDLNTLQEHIRCSHGFANPAA--------K 508
Y+C C ++ L+T E + C F+ +
Sbjct: 516 -----------YECKECGKLFIWRTAFLKHQSLHT-GEKLECEKTFSQDEELRGEQKIHQ 563
Query: 509 DSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNS 568
++ A++C C F S L H V T ++P Y C C +
Sbjct: 564 EAKAYWCNQCGRAFQGSSDLIRH---------------QVTHTREKP----YECKECGKT 604
Query: 569 PIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPA 628
FN L +H + + P N GK R S L I+ +
Sbjct: 605 --FNQSSDLLRHHRIHSGEKPYVCNKC--GKSFRGSSDL----IKHHRIH---------- 646
Query: 629 RPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIH 686
TGE Y C++CG ++ TH K H T C +C F + L++H +H
Sbjct: 647 --TGEKPYECSECGKAFSQRSHLATHQKIH--TGEKPYQCSECGNAFRRRSLLIQHRRLH 702
Query: 687 FMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHS 746
Y C+ C K F KH + C++ F +L +
Sbjct: 703 --SGEKPYECKECGKLFMWHTAFLKH---QRLHAGEKLEECEKTFSK--DEELRKEQRTH 755
Query: 747 NEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGES 791
EKKVY C C+ F+ +DL ++H + K ++C CG++
Sbjct: 756 QEKKVYWCNQCSRTFQGSSDL---IRHQVTHTREKPYECKECGKT 797
Score = 155 bits (392), Expect = 2e-37
Identities = 193/849 (22%), Positives = 289/849 (34%), Gaps = 187/849 (22%)
Query: 167 LHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHER 226
L G+ + F + L H K H NK Y+C C + F SS+L H ++H
Sbjct: 92 LSAGESSHRYEVSGQNFKQKSGLTEHQKIHNINKTYECKECEKTFNRSSNLIIHQRIHTG 151
Query: 227 NKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYC 286
NK C++C + + +L H H P C C
Sbjct: 152 NKP----------------YVCNECGKDSNQSSNLIIH-QRIHTGKKP------YICHEC 188
Query: 287 HELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQ--PESCNHSNSP 344
+ F + ++L+ H +Q+HSG C C ++F L H H + P CN
Sbjct: 189 GKDFNQSSNLVRH-KQIHSGGNPYECKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCG-- 245
Query: 345 SLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVT 404
K +Q T + +
Sbjct: 246 ---------------------------------------KAFSQSTDLIIHHRIHTGEKP 266
Query: 405 YSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD 464
Y C C Q+FS + L H + +KP + C C + +L EH +++H +
Sbjct: 267 YECYDCG-QMFSQSSHLVPHQRIHTGEKPLK---CNECEKAFRQHSHLTEH-QRLHSGEK 321
Query: 465 PGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIR---------CSHGFANPAA-------- 507
P Y+C+ C + + +H R C F+
Sbjct: 322 P-----------YECHRCGKTFSGRTAFLKHQRLHAGEKIEECEKTFSKDEELREEQRIH 370
Query: 508 KDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTN 567
++ A++C C F S L H V T ++P Y C C
Sbjct: 371 QEEKAYWCNQCGRNFQGTSDLIRH---------------QVTHTGEKP----YECKECGK 411
Query: 568 SPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAP 627
+ FN L +H + IH+G+K S + L V
Sbjct: 412 T--FNQSSDLLRHHR------------IHSGEKPCVCSKCGKSFRGSSDLIRHHRVH--- 454
Query: 628 ARPTGE--YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTI 685
TGE Y C++CG ++ TH K H T C +C K F + L++H I
Sbjct: 455 ---TGEKPYECSECGKAFSQRSHLVTHQKIH--TGEKPYQCTECGKAFRRRSLLIQHRRI 509
Query: 686 HFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKH 745
H Y C+ C K F KH +HT C ++ F +L K
Sbjct: 510 HS--GEKPYECKECGKLFIWRTAFLKHQ-SLHTGEKLEC---EKTFSQDE--ELRGEQKI 561
Query: 746 SNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTH 805
E K Y C C F+ +DL ++H + K ++C CG++F +L H H
Sbjct: 562 HQEAKAYWCNQCGRAFQGSSDL---IRHQVTHTREKPYECKECGKTFNQSSDLLRHHRIH 618
Query: 806 S--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLT 863
S K Y C C K+F L KH R + CG
Sbjct: 619 SGEKPYVCNKCGKSFRGSSDLIKHHRIHTGEKPYECSECG-------------------- 658
Query: 864 NSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKK-- 921
S SH + + + T E Y C CG A+ +LL H+ +P E K
Sbjct: 659 -KAFSQRSHLATHQKIHTGEKPYQCSECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLF 717
Query: 922 -------KAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTL 974
K + + K C +TF + LR+ +TH K Y C C F L
Sbjct: 718 MWHTAFLKHQRLHAGEKLEECEKTFSKDEELRKEQRTH-QEKKVYWCNQCSRTFQGSSDL 776
Query: 975 TEHKVTHSK 983
H+VTH++
Sbjct: 777 IRHQVTHTR 785
Score = 142 bits (359), Expect = 2e-33
Identities = 170/713 (23%), Positives = 252/713 (35%), Gaps = 124/713 (17%)
Query: 634 YICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTY 693
Y+CN+CG + H + H T C +C K+F +L++H IH
Sbjct: 155 YVCNECGKDSNQSSNLIIHQRIH--TGKKPYICHECGKDFNQSSNLVRHKQIHS--GGNP 210
Query: 694 YICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYR 753
Y C+ C K F +L H + C C + F + +H + H+ EK Y
Sbjct: 211 YECKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIHHRI-HTGEKP-YE 268
Query: 754 CTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNC 811
C C F + L V H + K KC C ++F L H HS K Y C
Sbjct: 269 CYDCGQMFSQSSHL---VPHQRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYEC 325
Query: 812 KFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVEL---QTLLTNSQES 868
C K F KH R H K C + ++ +EE + + +Q
Sbjct: 326 HRCGKTFSGRTAFLKHQR-LHA--GEKIEECEKTFSKDEELREEQRIHQEEKAYWCNQCG 382
Query: 869 HNSHDGSE----EDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKK-- 922
N S+ + T E Y C CG + + L LR H I GE V K
Sbjct: 383 RNFQGTSDLIRHQVTHTGEKPYECKECGKTFNQSSDL----LRHHRIHSGEKPCVCSKCG 438
Query: 923 ------AELIKGN--------YKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERF 968
++LI+ + Y+C+ C + F + L H + H G K Y C CG+ F
Sbjct: 439 KSFRGSSDLIRHHRVHTGEKPYECSECGKAFSQRSHLVTHQKIHTGE-KPYQCTECGKAF 497
Query: 969 PSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQT 1028
L +H+ HS C+ C FL+H +H TG + + C +T
Sbjct: 498 RRRSLLIQHRRIHSGEKPY-ECKECGKLFIWRTAFLKHQSLH-------TGEK-LECEKT 548
Query: 1029 VTSTLELKIHGTFHMQ----------KTGNGSAVQTTGRGQHV-QKLYKCASCLKEFRSK 1077
+ EL+ H + + GS+ + H +K Y+C C K F
Sbjct: 549 FSQDEELRGEQKIHQEAKAYWCNQCGRAFQGSSDLIRHQVTHTREKPYECKECGKTFNQS 608
Query: 1078 QDLVK---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVG 1134
DL++ + PY +C C + +S I + G
Sbjct: 609 SDLLRHHRIHSGEKPY-VCNKCGKSFRGSSDLIK-------------------HHRIHTG 648
Query: 1135 GLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKT 1194
CS C F S L H Q IH +K
Sbjct: 649 EKPYECSECGKAFSQRSHLATH-QKIHTG----------------------------EKP 679
Query: 1195 YQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGG 1254
YQC +C F + H H ++ +ECK C + F H H+ E
Sbjct: 680 YQCSECGNAFRRRSLLIQHRRLHSGEKP--YECKECGKLFMWHTAFLKHQRLHAGE---- 733
Query: 1255 TFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMT 1307
K C F + +L++ QE K+Y C QC + F ++L H +T
Sbjct: 734 --KLEECEKTFSKDEELRKE--QRTHQEKKVYWCNQCSRTFQGSSDLIRHQVT 782
Score = 139 bits (349), Expect = 2e-32
Identities = 191/837 (22%), Positives = 289/837 (34%), Gaps = 161/837 (19%)
Query: 413 QLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAM 472
Q F + L H K +++K + C+ C + NL H +++H P
Sbjct: 106 QNFKQKSGLTEHQKIHNINKTYE---CKECEKTFNRSSNLIIH-QRIHTGNKP------- 154
Query: 473 PAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHI 532
Y CN C + N + L H R G + C C F S+L H
Sbjct: 155 ----YVCNECGKDSNQSSNLIIHQRIHTG--------KKPYICHECGKDFNQSSNLVRH- 201
Query: 533 RQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLAL 592
+Q+H SG G+P Y C C + +S L L++ I K
Sbjct: 202 KQIH---SG---GNP------------YECKECGKAFKGSSNLVLHQRIHSRGKP----- 238
Query: 593 NYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGE--YICNQCGAKYTSLDSFQ 650
Y+ N K +A S + + I TGE Y C CG ++
Sbjct: 239 -YLCN-KCGKAFSQSTDLIIHHRI-------------HTGEKPYECYDCGQMFSQSSHLV 283
Query: 651 THLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQ 710
H + H T L C +C K F L +H +H Y C C K F+
Sbjct: 284 PHQRIH--TGEKPLKCNECEKAFRQHSHLTEHQRLHS--GEKPYECHRCGKTFSGRTAFL 339
Query: 711 KHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLH 770
KH + C++ F ++ + E+K Y C C +F+ +DL
Sbjct: 340 KH---QRLHAGEKIEECEKTFSKDEELREEQRIHQ--EEKAYWCNQCGRNFQGTSDL--- 391
Query: 771 VKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHL 828
++H K ++C CG++F +L H HS K C C K+F L +H
Sbjct: 392 IRHQVTHTGEKPYECKECGKTFNQSSDLLRHHRIHSGEKPCVCSKCGKSFRGSSDLIRHH 451
Query: 829 REKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGC 888
R + CG S SH + + + T E Y C
Sbjct: 452 RVHTGEKPYECSECG---------------------KAFSQRSHLVTHQKIHTGEKPYQC 490
Query: 889 DICGAAYTMETLLQNHQLRDHNIRPGESAIVKK---------KAELIKGNYKCNVCSRTF 939
CG A+ +LL H+ +P E K K + + K C +TF
Sbjct: 491 TECGKAFRRRSLLIQHRRIHSGEKPYECKECGKLFIWRTAFLKHQSLHTGEKLE-CEKTF 549
Query: 940 FSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQS 999
+ LR + H K Y C CG F L H+VTH++ C+ C
Sbjct: 550 SQDEELRGEQKIHQ-EAKAYWCNQCGRAFQGSSDLIRHQVTHTREKPY-ECKECGKTFNQ 607
Query: 1000 EEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQ 1059
+ L H ++H + + C C ++ + +L H H TG
Sbjct: 608 SSDLLRHHRIHSGEKP----YVCNKCGKSFRGSSDLIKHHRIH------------TG--- 648
Query: 1060 HVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRP 1116
+K Y+C+ C K F + L K+ PY C+ C N + R
Sbjct: 649 --EKPYECSECGKAFSQRSHLATHQKIHTGEKPYQ-CSECGNAFR------------RRS 693
Query: 1117 GLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTP 1176
L Q+ L + G C C F + H + E + + T K
Sbjct: 694 LLIQHRRLHS-------GEKPYECKECGKLFMWHTAFLKHQRLHAGEKLEECEKTFSKDE 746
Query: 1177 QVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQT 1233
++ R EKK Y C +C F D+ H H ++ +ECK C +T
Sbjct: 747 ELRKEQRTH----QEKKVYWCNQCSRTFQGSSDLIRHQVTHTREK--PYECKECGKT 797
Score = 133 bits (335), Expect = 1e-30
Identities = 157/646 (24%), Positives = 241/646 (37%), Gaps = 93/646 (14%)
Query: 671 KEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEV 730
+ F + L +H IH I TY C+ C+K F +L H + C C +
Sbjct: 106 QNFKQKSGLTEHQKIH-NINKTYE-CKECEKTFNRSSNLIIHQRIHTGNKPYVCNECGK- 162
Query: 731 FDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGE 790
DS S L + + KK Y C C DF ++L V+H + + G ++C CG+
Sbjct: 163 -DSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNL---VRHKQIHSGGNPYECKECGK 218
Query: 791 SFGTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGT--NG 846
+F L H HS K Y C C KAF L H R + +CG +
Sbjct: 219 AFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYECYDCGQMFSQ 278
Query: 847 ASEQVQKEEVEL--QTLLTNSQES---HNSHDGSEEDVDTSEPMYGCDICGAAYTMETLL 901
+S V + + + L N E +SH + + + E Y C CG ++ T
Sbjct: 279 SSHLVPHQRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRTAF 338
Query: 902 QNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMC 961
HQ + GE K C +TF + LRE + H K Y C
Sbjct: 339 LKHQ----RLHAGE---------------KIEECEKTFSKDEELREEQRIHQEE-KAYWC 378
Query: 962 PICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFR 1021
CG F L H+VTH+ C+ C + L H ++H + +
Sbjct: 379 NQCGRNFQGTSDLIRHQVTHTGEKPY-ECKECGKTFNQSSDLLRHHRIHSGEKPCV---- 433
Query: 1022 CVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV 1081
C C ++ + +L H H TG +K Y+C+ C K F + LV
Sbjct: 434 CSKCGKSFRGSSDLIRHHRVH------------TG-----EKPYECSECGKAFSQRSHLV 476
Query: 1082 ---KLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKT 1138
K+ PY C C + R L Q+ + + G
Sbjct: 477 THQKIHTGEKPYQ-CTECGKAFR------------RRSLLIQHRRIHS-------GEKPY 516
Query: 1139 RCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCI 1198
C C F + H Q++H + T + ++ +I E K Y C
Sbjct: 517 ECKECGKLFIWRTAFLKH-QSLHTGEKLECEKTFSQDEELRGEQKIH----QEAKAYWCN 571
Query: 1199 KCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKC 1258
+C F D+ H H ++ +ECK C +TF+ + L H HS E + C
Sbjct: 572 QCGRAFQGSSDLIRHQVTHTREKP--YECKECGKTFNQSSDLLRHHRIHSGE---KPYVC 626
Query: 1259 PVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
C F ++ L +H G +K Y+C++C + F ++ L H
Sbjct: 627 NKCGKSFRGSSDLIKHHRIHTG--EKPYECSECGKAFSQRSHLATH 670
Score = 132 bits (331), Expect = 3e-30
Identities = 95/355 (26%), Positives = 144/355 (40%), Gaps = 96/355 (27%)
Query: 30 DCKKRPEDGEEL-EDEAVHS------CDSCLQVFESLSDITEHKINQCQLTDGVDVEDDP 82
+C+K EEL E++ +H C+ C + F+ SD+ H++
Sbjct: 352 ECEKTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHT------------ 399
Query: 83 TCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSD 142
GE+ PY C+ C K+F++ S L H + HS
Sbjct: 400 -------------------------GEK------PYECKECGKTFNQSSDLLRHHRIHSG 428
Query: 143 KLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPY 202
+ P C+ C + F+ RH ++HTG+K Y CSEC AFS+ HL H K HT KPY
Sbjct: 429 EKPCVCSKCGKSFRGSSDLIRHHRVHTGEKPYECSECGKAFSQRSHLVTHQKIHTGEKPY 488
Query: 203 KCAICRRGFLSSSSLHGHMQVHERNK--------------------DGSQSGSRME---- 238
+C C + F S L H ++H K +G ++E
Sbjct: 489 QCTECGKAFRRRSLLIQHRRIHSGEKPYECKECGKLFIWRTAFLKHQSLHTGEKLECEKT 548
Query: 239 ---DWKMKDTQK---------CSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYC 286
D +++ QK C+QC F DL +H H P E C C
Sbjct: 549 FSQDEELRGEQKIHQEAKAYWCNQCGRAFQGSSDLIRH-QVTHTREKPYE------CKEC 601
Query: 287 HELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSH--QQPESCN 339
+ F + + L+ H ++HSGEK C+ C +SF +L H H ++P C+
Sbjct: 602 GKTFNQSSDLLRH-HRIHSGEKPYVCNKCGKSFRGSSDLIKHHRIHTGEKPYECS 655
Score = 124 bits (311), Expect = 6e-28
Identities = 79/309 (25%), Positives = 132/309 (42%), Gaps = 67/309 (21%)
Query: 26 GEALDCKKRPEDGEELE-DEAVHS------CDSCLQVFESLSDITEHKINQCQLTDGVDV 78
GE L+C+K EEL ++ +H C+ C + F+ SD+ H++ +
Sbjct: 540 GEKLECEKTFSQDEELRGEQKIHQEAKAYWCNQCGRAFQGSSDLIRHQVTHTR------- 592
Query: 79 EDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQ 138
PY C+ C K+F++ S L H +
Sbjct: 593 ------------------------------------EKPYECKECGKTFNQSSDLLRHHR 616
Query: 139 SHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTS 198
HS + P+ C C + F+ +H ++HTG+K Y CSEC AFS+ HL H K HT
Sbjct: 617 IHSGEKPYVCNKCGKSFRGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATHQKIHTG 676
Query: 199 NKPYKCAICRRGFLSSSSLHGHMQVH--ERNKDGSQSG-------SRMEDWKMKDTQKCS 249
KPY+C+ C F S L H ++H E+ + + G + ++ ++ +K
Sbjct: 677 EKPYQCSECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLFMWHTAFLKHQRLHAGEKLE 736
Query: 250 QCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKK 309
+CE+ F E+L+K E ++++ C C F + L+ H + H+ EK
Sbjct: 737 ECEKTFSKDEELRK-------EQRTHQEKKVYWCNQCSRTFQGSSDLIRH-QVTHTREKP 788
Query: 310 NSCSICSES 318
C C ++
Sbjct: 789 YECKECGKT 797
Score = 80.9 bits (198), Expect = 8e-15
Identities = 103/455 (22%), Positives = 161/455 (35%), Gaps = 78/455 (17%)
Query: 869 HNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKG 928
H ++G E+ + E + ++ G + ++ L HQ + HNI
Sbjct: 83 HGCNEG-EKILSAGESSHRYEVSGQNFKQKSGLTEHQ-KIHNINK--------------- 125
Query: 929 NYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTG 988
Y+C C +TF + L H + H G K Y+C CG+ L H+ H TG
Sbjct: 126 TYECKECEKTFNRSSNLIIHQRIHTGN-KPYVCNECGKDSNQSSNLIIHQRIH-----TG 179
Query: 989 N----CRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQ 1044
C C + H Q+H + + C C + + L +H H
Sbjct: 180 KKPYICHECGKDFNQSSNLVRHKQIH----SGGNPYECKECGKAFKGSSNLVLHQRIH-- 233
Query: 1045 KTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLV---KLDINGLPYGLCAGCVNLSK 1101
RG K Y C C K F DL+ ++ PY C + +
Sbjct: 234 -----------SRG----KPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYE----CYDCGQ 274
Query: 1102 SASPGINVPPG----TNRPGLGQNENLSAIEGKGKV--------GGLKTRCSSCNVKFES 1149
S ++ P T L NE A + G C C F
Sbjct: 275 MFSQSSHLVPHQRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSG 334
Query: 1150 ESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWD 1209
+ H + E + + T K ++ RI E+K Y C +C F D
Sbjct: 335 RTAFLKHQRLHAGEKIEECEKTFSKDEELREEQRIH----QEEKAYWCNQCGRNFQGTSD 390
Query: 1210 IQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQAN 1269
+ H H ++ +ECK C +TF+ + L H HS E C C F ++
Sbjct: 391 LIRHQVTHTGEKP--YECKECGKTFNQSSDLLRHHRIHSGE---KPCVCSKCGKSFRGSS 445
Query: 1270 KLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNH 1304
L +H G +K Y+C++C + F ++ L H
Sbjct: 446 DLIRHHRVHTG--EKPYECSECGKAFSQRSHLVTH 478
Score = 60.5 bits (145), Expect = 1e-08
Identities = 80/352 (22%), Positives = 126/352 (35%), Gaps = 64/352 (18%)
Query: 963 ICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRC 1022
+ G+ F LTEH+ H+ + T C+ C+ + H ++H + + C
Sbjct: 103 VSGQNFKQKSGLTEHQKIHNIN-KTYECKECEKTFNRSSNLIIHQRIHTGNKP----YVC 157
Query: 1023 VVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK 1082
C + + L IH H K K Y C C K+F +LV+
Sbjct: 158 NECGKDSNQSSNLIIHQRIHTGK-----------------KPYICHECGKDFNQSSNLVR 200
Query: 1083 ---LDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTR 1139
+ G PY C C K +S + L Q I +GK
Sbjct: 201 HKQIHSGGNPYE-CKECGKAFKGSSNLV----------LHQR-----IHSRGK----PYL 240
Query: 1140 CSSCNVKFESESELQNHIQTIHRELVP----DSNSTQLKTPQVSPMPRISPSQSDEKKTY 1195
C+ C F ++L H IH P D ++ + P RI + K
Sbjct: 241 CNKCGKAFSQSTDLIIH-HRIHTGEKPYECYDCGQMFSQSSHLVPHQRIHTGE----KPL 295
Query: 1196 QCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGT 1255
+C +C+ F + H H ++ +EC C +TF H H+ E
Sbjct: 296 KCNECEKAFRQHSHLTEHQRLHSGEKP--YECHRCGKTFSGRTAFLKHQRLHAGE----- 348
Query: 1256 FKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMT 1307
K C F + +L++ QE+K Y C QC + F ++L H +T
Sbjct: 349 -KIEECEKTFSKDEELREE--QRIHQEEKAYWCNQCGRNFQGTSDLIRHQVT 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.131 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,229,244
Number of Sequences: 37866
Number of extensions: 3076628
Number of successful extensions: 110443
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1051
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 9239
Number of HSP's gapped (non-prelim): 21733
length of query: 1311
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1197
effective length of database: 13,930,794
effective search space: 16675160418
effective search space used: 16675160418
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.