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Search of human proteins with 240255478
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens]
(867 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens] 1828 0.0
gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens] 1823 0.0
gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens] 1823 0.0
gi|189571643 sulfatase 1 [Homo sapiens] 1206 0.0
gi|189571641 sulfatase 1 [Homo sapiens] 1206 0.0
gi|189571638 sulfatase 1 [Homo sapiens] 1206 0.0
gi|189571636 sulfatase 1 [Homo sapiens] 1206 0.0
gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo sa... 313 6e-85
gi|39930577 arylsulfatase K [Homo sapiens] 97 8e-20
gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens] 65 3e-10
gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precurso... 65 4e-10
gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10
gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10
gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10
gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10
gi|109389362 arylsulfatase J [Homo sapiens] 59 2e-08
gi|59797060 arylsulfatase family, member I [Homo sapiens] 58 4e-08
gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens] 56 1e-07
gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens] 55 2e-07
gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens] 54 5e-07
gi|53831991 steryl-sulfatase precursor [Homo sapiens] 54 6e-07
gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo sap... 52 2e-06
gi|31742482 arylsulfatase F precursor [Homo sapiens] 49 2e-05
gi|45430057 Arylsulfatase G [Homo sapiens] 49 2e-05
gi|146229327 arylsulfatase A isoform b [Homo sapiens] 48 3e-05
gi|58743319 arylsulfatase family, member H [Homo sapiens] 47 6e-05
gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens] 44 8e-04
gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens] 43 0.001
gi|157266309 arylsulfatase E precursor [Homo sapiens] 40 0.007
gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa... 32 1.9
>gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens]
Length = 867
Score = 1828 bits (4735), Expect = 0.0
Identities = 867/867 (100%), Positives = 867/867 (100%)
Query: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60
MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS
Sbjct: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60
Query: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120
MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA
Sbjct: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120
Query: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180
QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK
Sbjct: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180
Query: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240
EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP
Sbjct: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240
Query: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300
NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM
Sbjct: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300
Query: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360
LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV
Sbjct: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360
Query: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420
LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL
Sbjct: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420
Query: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480
HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP
Sbjct: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480
Query: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540
MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV
Sbjct: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540
Query: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600
AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT
Sbjct: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600
Query: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660
HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC
Sbjct: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660
Query: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720
DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC
Sbjct: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720
Query: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780
SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE
Sbjct: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780
Query: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLDGGSYEQYR 840
YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLDGGSYEQYR
Sbjct: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLDGGSYEQYR 840
Query: 841 QFQRRKWPEMKRPSSKSLGQLWEGWEG 867
QFQRRKWPEMKRPSSKSLGQLWEGWEG
Sbjct: 841 QFQRRKWPEMKRPSSKSLGQLWEGWEG 867
>gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens]
Length = 870
Score = 1823 bits (4721), Expect = 0.0
Identities = 867/870 (99%), Positives = 867/870 (99%), Gaps = 3/870 (0%)
Query: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60
MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS
Sbjct: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60
Query: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120
MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA
Sbjct: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120
Query: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180
QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK
Sbjct: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180
Query: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240
EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP
Sbjct: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240
Query: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300
NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM
Sbjct: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300
Query: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360
LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV
Sbjct: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360
Query: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420
LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL
Sbjct: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420
Query: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480
HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP
Sbjct: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480
Query: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540
MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV
Sbjct: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540
Query: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600
AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT
Sbjct: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600
Query: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660
HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC
Sbjct: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660
Query: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720
DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC
Sbjct: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720
Query: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780
SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE
Sbjct: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780
Query: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDL---DGGSYE 837
YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDL DGGSYE
Sbjct: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 840
Query: 838 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 867
QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG
Sbjct: 841 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870
>gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens]
Length = 870
Score = 1823 bits (4721), Expect = 0.0
Identities = 867/870 (99%), Positives = 867/870 (99%), Gaps = 3/870 (0%)
Query: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60
MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS
Sbjct: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60
Query: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120
MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA
Sbjct: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120
Query: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180
QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK
Sbjct: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180
Query: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240
EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP
Sbjct: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240
Query: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300
NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM
Sbjct: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300
Query: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360
LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV
Sbjct: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360
Query: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420
LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL
Sbjct: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420
Query: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480
HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP
Sbjct: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480
Query: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540
MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV
Sbjct: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540
Query: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600
AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT
Sbjct: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600
Query: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660
HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC
Sbjct: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660
Query: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720
DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC
Sbjct: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720
Query: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780
SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE
Sbjct: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780
Query: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDL---DGGSYE 837
YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDL DGGSYE
Sbjct: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 840
Query: 838 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 867
QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG
Sbjct: 841 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870
>gi|189571643 sulfatase 1 [Homo sapiens]
Length = 871
Score = 1206 bits (3120), Expect = 0.0
Identities = 577/891 (64%), Positives = 697/891 (78%), Gaps = 54/891 (6%)
Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64
+LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM
Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63
Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124
NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE
Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123
Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184
RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG
Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183
Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244
DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ
Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243
Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304
HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET
Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303
Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364
GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID
Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363
Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424
LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++
Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423
Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484
+ Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L
Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483
Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537
R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R
Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543
Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583
RS+++E +G +Y + L + QPRN+ KRH G P D GG D S
Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603
Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643
G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK
Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658
Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700
NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E
Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718
Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759
+R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC
Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778
Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819
+RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY
Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838
Query: 820 KQCNPRTRNMDL---DGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 867
KQCNPR +N+D+ DGGSY+ +R GQLW+GWEG
Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871
>gi|189571641 sulfatase 1 [Homo sapiens]
Length = 871
Score = 1206 bits (3120), Expect = 0.0
Identities = 577/891 (64%), Positives = 697/891 (78%), Gaps = 54/891 (6%)
Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64
+LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM
Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63
Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124
NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE
Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123
Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184
RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG
Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183
Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244
DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ
Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243
Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304
HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET
Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303
Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364
GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID
Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363
Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424
LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++
Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423
Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484
+ Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L
Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483
Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537
R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R
Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543
Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583
RS+++E +G +Y + L + QPRN+ KRH G P D GG D S
Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603
Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643
G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK
Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658
Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700
NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E
Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718
Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759
+R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC
Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778
Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819
+RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY
Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838
Query: 820 KQCNPRTRNMDL---DGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 867
KQCNPR +N+D+ DGGSY+ +R GQLW+GWEG
Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871
>gi|189571638 sulfatase 1 [Homo sapiens]
Length = 871
Score = 1206 bits (3120), Expect = 0.0
Identities = 577/891 (64%), Positives = 697/891 (78%), Gaps = 54/891 (6%)
Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64
+LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM
Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63
Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124
NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE
Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123
Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184
RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG
Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183
Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244
DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ
Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243
Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304
HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET
Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303
Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364
GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID
Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363
Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424
LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++
Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423
Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484
+ Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L
Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483
Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537
R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R
Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543
Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583
RS+++E +G +Y + L + QPRN+ KRH G P D GG D S
Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603
Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643
G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK
Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658
Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700
NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E
Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718
Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759
+R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC
Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778
Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819
+RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY
Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838
Query: 820 KQCNPRTRNMDL---DGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 867
KQCNPR +N+D+ DGGSY+ +R GQLW+GWEG
Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871
>gi|189571636 sulfatase 1 [Homo sapiens]
Length = 871
Score = 1206 bits (3120), Expect = 0.0
Identities = 577/891 (64%), Positives = 697/891 (78%), Gaps = 54/891 (6%)
Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64
+LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM
Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63
Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124
NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE
Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123
Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184
RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG
Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183
Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244
DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ
Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243
Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304
HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET
Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303
Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364
GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID
Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363
Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424
LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++
Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423
Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484
+ Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L
Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483
Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537
R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R
Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543
Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583
RS+++E +G +Y + L + QPRN+ KRH G P D GG D S
Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603
Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643
G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK
Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658
Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700
NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E
Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718
Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759
+R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC
Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778
Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819
+RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY
Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838
Query: 820 KQCNPRTRNMDL---DGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 867
KQCNPR +N+D+ DGGSY+ +R GQLW+GWEG
Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871
>gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo
sapiens]
Length = 552
Score = 313 bits (801), Expect = 6e-85
Identities = 170/359 (47%), Positives = 218/359 (60%), Gaps = 15/359 (4%)
Query: 43 RPNIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVH 102
RPN++L+LTDDQD LG M + KT+ ++ + G F +A+V + +CCPSR+SILTGKY H
Sbjct: 46 RPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPH 105
Query: 103 NHNTYTNN--ENCSSPSWQAQHESRTFAVYLNST-GYRTAFFGKYLNEYNG------SYV 153
NH+ N NCSS SWQ E TF L S GY+T F GKYLNEY +V
Sbjct: 106 NHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHV 165
Query: 154 PPGWKEWVGLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPH 213
P GW W L KNS++YNYTL NG KHG +YS DYLTD++ N S+ F
Sbjct: 166 PLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNF--- 222
Query: 214 RPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTG-PMKPIH 272
P M+I+ APH P +APQY + F N ++N +KHW++R PM
Sbjct: 223 EPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIH-GTNKHWLIRQAKTPMTNSS 281
Query: 273 MEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHIGQFGLVKGKS 332
++F + RKR QTL+SVDD +E + L TGEL+NTYI YT+D+GYH GQF L K
Sbjct: 282 IQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKR 341
Query: 333 MPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDI-PADMDGKSILKLL 390
YEFDI+VP VRGP ++ + +V NIDL PTILDIAG D+ MDG S+L +L
Sbjct: 342 QLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPIL 400
Score = 67.8 bits (164), Expect = 4e-11
Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 745 PFCACTSANNNTYWCMRTINETHNFLFCEFATG--FLEYFDLNTDPYQLMNAVNTLDRDV 802
P C C A NNTY C+RT++ N +CEF F+E ++L DP Q+ N T+D ++
Sbjct: 440 PDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPEL 499
Query: 803 LNQLHVQLMELRSCKG 818
L +++ +LM L+SC G
Sbjct: 500 LGKMNYRLMMLQSCSG 515
>gi|39930577 arylsulfatase K [Homo sapiens]
Length = 536
Score = 96.7 bits (239), Expect = 8e-20
Identities = 98/382 (25%), Positives = 170/382 (44%), Gaps = 49/382 (12%)
Query: 36 QRDRRNIRPNIILVLTDDQDVEL----GSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPS 91
QR R PN++LV++D D L GS V M+ G F+NA+ +P+CCPS
Sbjct: 24 QRRRAAKAPNVVLVVSDSFDGRLTFHPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPS 83
Query: 92 RSSILTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK--YLNEYN 149
R+++ +G + H ++ NN P++ T+ + GYRT FGK Y + ++
Sbjct: 84 RAAMWSGLFTHLTESW-NNFKGLDPNY------TTWMDVMERHGYRTQKFGKLDYTSGHH 136
Query: 150 --GSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTS 207
+ V ++ LL+ L RN K + +D+ T+ +V++ R
Sbjct: 137 SISNRVEAWTRDVAFLLRQEGRPMVNLIRNRTKVR---VMERDWQN---TDKAVNWLRKE 190
Query: 208 KKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSY------------NYAPN 255
Y P ++ + PH P S P F +++ H + + ++P
Sbjct: 191 AINYT-EPFVIYLGLNLPH-PYPS-PSSGENFGSSTFHTSLYWLEKVSHDAIKIPKWSPL 247
Query: 256 PDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMS--------VDDSMETIYNMLVETGEL 307
+ H + Y+ K FT +K ++ + + D + I L + L
Sbjct: 248 SEMHPVDYYSSYTKNCTGRFT----KKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLL 303
Query: 308 DNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAP 367
T ++Y++DHG + SM YE VP + GP ++AG ++V +D+ P
Sbjct: 304 QKTIVIYSSDHGELAMEHRQFYKMSM-YEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYP 362
Query: 368 TILDIAGLDIPADMDGKSILKL 389
T+LDIAG+ +P ++ G S+L L
Sbjct: 363 TMLDIAGIPLPQNLSGYSLLPL 384
Score = 30.4 bits (67), Expect = 7.4
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 715 QNNDTCSMPGLTCFTHDNQHW--QTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFC 772
QN S+ L+ T N+H P W L F C + N +TY M N +
Sbjct: 374 QNLSGYSLLPLSSETFKNEHKVKNLHPPWILSEFHGC-NVNASTY--MLRTNHWKYIAYS 430
Query: 773 EFATGFLEYFDLNTDPYQLMN 793
+ A+ + FDL++DP +L N
Sbjct: 431 DGASILPQLFDLSSDPDELTN 451
>gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens]
Length = 550
Score = 65.1 bits (157), Expect = 3e-10
Identities = 92/447 (20%), Positives = 161/447 (36%), Gaps = 84/447 (18%)
Query: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAH---FINAFVTTPMCCPSRSSILTGKYV 101
N++L++ DD LG ++Q +H F NAF +C PSR S LTG+
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 102 HNHNTYTNNENCSSPSWQAQHES-RTFAVYLNSTGYRTAFFGKY----LNEYNGSYVPPG 156
Y N W+ + T Y GY T GK ++ + P
Sbjct: 98 DTTRLYDFNSY-----WRVHAGNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYS 152
Query: 157 WKEWVGLLKNSRFYNYTLCRNGVKEKHGS--------DYSKDYLTDLITNDSVSFFRTSK 208
W + ++ N CR E H + D + L D + + + K
Sbjct: 153 WSFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQ-AIQLLEK 211
Query: 209 KMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYA----PNPDKHWI--- 261
P + + + PH P ++ +L+P + + P P W+
Sbjct: 212 MKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIR 271
Query: 262 -------MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVY 314
+ + P PI ++F +++ ++ +D + + + L + ++T I +
Sbjct: 272 QREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAF 331
Query: 315 TADHGYHIGQFG-LVKGKSMPYEFDIRVPFYVRGPN-----------------------V 350
T+DHG+ +G+ G K + + + FYV G +
Sbjct: 332 TSDHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLM 391
Query: 351 EAGCLNPHIVLNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRD 410
E G + +V + L PT+ +AGL +P PV FH++
Sbjct: 392 EPGRQSMDLVELVSLFPTLAGLAGLQVP-------------PRCPVPSFHVE-------- 430
Query: 411 SFLVERGKLLHKRDNDKVDAQEENFLP 437
L GK L K + D +E+ +LP
Sbjct: 431 --LCREGKNLLKHFRFR-DLEEDPYLP 454
>gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precursor
[Homo sapiens]
Length = 522
Score = 64.7 bits (156), Expect = 4e-10
Identities = 97/396 (24%), Positives = 152/396 (38%), Gaps = 87/396 (21%)
Query: 44 PNIILVLTDDQDV-ELG-----SMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILT 97
PNI+L+L DD +LG S + N R E G F N + P+C PSR+++LT
Sbjct: 31 PNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAE--GLLFPNFYSANPLCSPSRAALLT 88
Query: 98 GKYVHNHNTYTNNENCSSPSWQAQ------HESRTFAVYLNSTGYRTAFFGKYLNEYNGS 151
G+ + YT N + + + + L GY + GK+ +
Sbjct: 89 GRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQ 148
Query: 152 YVP--PGWKEWVGLLKNSRFYNY-TLCRNGVK-----EKHGSDYSK---------DYLTD 194
+ P G+ EW G N F Y R + E G Y + LT
Sbjct: 149 FHPLKHGFDEWFGS-PNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQ 207
Query: 195 LITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAP 254
+ +++ F K+ H P + + A H P YA
Sbjct: 208 IYLQEALDFI---KRQARHHPFFLYWAVDATHAPV----------------------YAS 242
Query: 255 NPDKHWIMRYTGPMKPIHMEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIV 313
P F QR R + +DDS+ I +L + DNT++
Sbjct: 243 KP------------------FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVF 284
Query: 314 YTADHGYHI-------GQFG-LVKGKSMPYEFDIRVPFYVRGP-NVEAGCLNPHIVLNID 364
+T+D+G + G G + GK +E +R P P +V AG ++ + +D
Sbjct: 285 FTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMD 344
Query: 365 LAPTILDIAGLDIPAD--MDGKSILKLLDTERPVNR 398
L T L +AGL P+D +DG ++L L R ++R
Sbjct: 345 LFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDR 380
>gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 64.3 bits (155), Expect = 5e-10
Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%)
Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99
PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155
Y SS E T A L + GY T GK+ G+++PP
Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139
Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212
G+ ++G+ + N T G D + L+ N SV + P
Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192
Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272
P L A H L +A + P + Y + H+ +++G
Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235
Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325
F R +LM +D ++ T+ + + G L+ T +++TAD+G G
Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295
Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383
GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG
Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355
Query: 384 KSILKLL 390
+ LL
Sbjct: 356 FDLSPLL 362
>gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 64.3 bits (155), Expect = 5e-10
Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%)
Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99
PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155
Y SS E T A L + GY T GK+ G+++PP
Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139
Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212
G+ ++G+ + N T G D + L+ N SV + P
Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192
Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272
P L A H L +A + P + Y + H+ +++G
Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235
Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325
F R +LM +D ++ T+ + + G L+ T +++TAD+G G
Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295
Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383
GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG
Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355
Query: 384 KSILKLL 390
+ LL
Sbjct: 356 FDLSPLL 362
>gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 64.3 bits (155), Expect = 5e-10
Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%)
Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99
PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155
Y SS E T A L + GY T GK+ G+++PP
Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139
Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212
G+ ++G+ + N T G D + L+ N SV + P
Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192
Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272
P L A H L +A + P + Y + H+ +++G
Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235
Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325
F R +LM +D ++ T+ + + G L+ T +++TAD+G G
Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295
Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383
GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG
Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355
Query: 384 KSILKLL 390
+ LL
Sbjct: 356 FDLSPLL 362
>gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 64.3 bits (155), Expect = 5e-10
Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%)
Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99
PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155
Y SS E T A L + GY T GK+ G+++PP
Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139
Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212
G+ ++G+ + N T G D + L+ N SV + P
Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192
Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272
P L A H L +A + P + Y + H+ +++G
Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235
Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325
F R +LM +D ++ T+ + + G L+ T +++TAD+G G
Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295
Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383
GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG
Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355
Query: 384 KSILKLL 390
+ LL
Sbjct: 356 FDLSPLL 362
>gi|109389362 arylsulfatase J [Homo sapiens]
Length = 599
Score = 58.9 bits (141), Expect = 2e-08
Identities = 86/373 (23%), Positives = 144/373 (38%), Gaps = 73/373 (19%)
Query: 43 RPNIILVLTDDQ---DVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGK 99
+P++I +L DDQ DV ++ T + G N +V P+C PSRS +TGK
Sbjct: 75 QPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQ-PICTPSRSQFITGK 133
Query: 100 Y-VHNHNTYT----NNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY-LNEYNGSYV 153
Y +H ++ NC ++ T L GY T GK+ L Y +
Sbjct: 134 YQIHTGLQHSIIRPTQPNC------LPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECM 187
Query: 154 PP--GWKEWVGLLKNSRFYNYT--------LCRNGVKEKHGSDYSKD---YLTDLITNDS 200
P G+ + G L S Y YT +C + E + + D Y T + T
Sbjct: 188 PTRRGFDTFFGSLLGSGDY-YTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRV 246
Query: 201 VSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHW 260
+ P +P+ + I++ A H P + +Y +H
Sbjct: 247 QQILASHN---PTKPIFLYIAYQAVHSPLQAPGRYF-------EH--------------- 281
Query: 261 IMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGY 320
+ N+ +R+ L +D+++ + L G +N+ I+Y++D+G
Sbjct: 282 -----------YRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGG 330
Query: 321 HIGQFG----LVKGKSMPYEFDIRVPFYVRGPNVE-AGCLNPHIVLNIDLAPTILDIAGL 375
G L K +E IR +V P ++ G + +V D PT++ +A
Sbjct: 331 QPTAGGSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEG 390
Query: 376 DIPAD--MDGKSI 386
I D +DG I
Sbjct: 391 QIDEDIQLDGYDI 403
>gi|59797060 arylsulfatase family, member I [Homo sapiens]
Length = 569
Score = 57.8 bits (138), Expect = 4e-08
Identities = 84/355 (23%), Positives = 139/355 (39%), Gaps = 66/355 (18%)
Query: 44 PNIILVLTDDQ---DVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKY 100
P+II +LTDDQ DV + T + G N ++ P+C PSRS +LTG+Y
Sbjct: 47 PHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQ-PICTPSRSQLLTGRY 105
Query: 101 -VH---NHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK-YLNEYNGSYVPP 155
+H H+ + P Q T L GY T GK +L Y +P
Sbjct: 106 QIHTGLQHSIIRPQQPNCLPLDQV-----TLPQKLQEAGYSTHMVGKWHLGFYRKECLPT 160
Query: 156 --GWKEWVG-LLKNSRFYNYTLCRN----GVKEKHGSD----YSKDYLTDLITNDSVSFF 204
G+ ++G L N +Y Y C G G + S Y T L +
Sbjct: 161 RRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHIL 220
Query: 205 RTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRY 264
+ P RP+ + ++ A H P S +Y + RY
Sbjct: 221 ASHS---PQRPLFLYVAFQAVHTPLQSPREY-------------------------LYRY 252
Query: 265 TGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHG---YH 321
N+ +RK + +D+++ I L G +N+ I++++D+G +
Sbjct: 253 --------RTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFS 304
Query: 322 IGQFGLVKGKSMPY-EFDIRVPFYVRGPNVEAGCLNPHIVLNI-DLAPTILDIAG 374
G ++G+ Y E +R +V P ++ +++I D PT++ +AG
Sbjct: 305 GGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAG 359
>gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens]
Length = 533
Score = 56.2 bits (134), Expect = 1e-07
Identities = 92/429 (21%), Positives = 165/429 (38%), Gaps = 84/429 (19%)
Query: 44 PNIILVLTDD---QDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKY 100
P+++ +L DD DV ++ + GG ++ + T P+C PSRS +LTG+Y
Sbjct: 45 PHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGV-LLDNYYTQPLCTPSRSQLLTGRY 103
Query: 101 VHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK-YLNEYNGSYVPP--GW 157
PS E + L GY T GK +L Y +P G+
Sbjct: 104 QIRTGLQHQIIWPCQPSCVPLDE-KLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGF 162
Query: 158 KEWVGLLKNSRFY------------NYTLC----RNGVKEKHGSDYSKDYLTDLITNDSV 201
+ G L S Y N T C R+G E+ + Y Y T++ T ++
Sbjct: 163 DTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDG--EEVATGYKNMYSTNIFTKRAI 220
Query: 202 SFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWI 261
+ P +P+ + ++ + H P +Y + Y++ + ++H
Sbjct: 221 ALITNHP---PEKPLFLYLALQSVHEPLQVPEEYLK-----------PYDFIQDKNRH-- 264
Query: 262 MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321
Y G + +LM D+++ + L +G +NT +++ D+G
Sbjct: 265 -HYAG-----------------MVSLM--DEAVGNVTAALKSSGLWNNTVFIFSTDNG-- 302
Query: 322 IGQFGLVKGKSMP--------YEFDIRVPFYVRGPNV-EAGCLNPHIVLNIDLAPTILDI 372
GQ L G + P +E +R +V P + + G N ++ D PT++ +
Sbjct: 303 -GQ-TLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL 360
Query: 373 A--GLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRDNDKVDA 430
A + +DG + K + P R L + D V+ N A
Sbjct: 361 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNI----DPNFVDSSPCPR---NSMAPA 413
Query: 431 QEENFLPKY 439
++++ LP+Y
Sbjct: 414 KDDSSLPEY 422
>gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens]
Length = 413
Score = 55.5 bits (132), Expect = 2e-07
Identities = 85/391 (21%), Positives = 151/391 (38%), Gaps = 77/391 (19%)
Query: 44 PNIILVLTDD---QDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKY 100
P+++ +L DD DV ++ + GG ++ + T P+C PSRS +LTG+Y
Sbjct: 45 PHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGV-LLDNYYTQPLCTPSRSQLLTGRY 103
Query: 101 VHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK-YLNEYNGSYVPP--GW 157
PS E + L GY T GK +L Y +P G+
Sbjct: 104 QIRTGLQHQIIWPCQPSCVPLDE-KLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGF 162
Query: 158 KEWVGLLKNSRFY------------NYTLC----RNGVKEKHGSDYSKDYLTDLITNDSV 201
+ G L S Y N T C R+G E+ + Y Y T++ T ++
Sbjct: 163 DTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDG--EEVATGYKNMYSTNIFTKRAI 220
Query: 202 SFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWI 261
+ P +P+ + ++ + H P +Y + Y++ + ++H
Sbjct: 221 ALITNHP---PEKPLFLYLALQSVHEPLQVPEEYLK-----------PYDFIQDKNRH-- 264
Query: 262 MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321
Y G + +LM D+++ + L +G +NT +++ D+G
Sbjct: 265 -HYAG-----------------MVSLM--DEAVGNVTAALKSSGLWNNTVFIFSTDNG-- 302
Query: 322 IGQFGLVKGKSMP--------YEFDIRVPFYVRGPNV-EAGCLNPHIVLNIDLAPTILDI 372
GQ L G + P +E +R +V P + + G N ++ D PT++ +
Sbjct: 303 -GQ-TLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL 360
Query: 373 A--GLDIPADMDGKSILKLLDTERPVNRFHL 401
A + +DG + K + P R L
Sbjct: 361 ARGHTNGTKPLDGFDVWKTISEGSPSPRIEL 391
>gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens]
Length = 343
Score = 54.3 bits (129), Expect = 5e-07
Identities = 62/306 (20%), Positives = 113/306 (36%), Gaps = 36/306 (11%)
Query: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAH---FINAFVTTPMCCPSRSSILTGKYV 101
N++L++ DD LG ++Q +H F NAF +C PSR S LTG+
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 102 HNHNTYTNNENCSSPSWQAQHES-RTFAVYLNSTGYRTAFFGKY----LNEYNGSYVPPG 156
Y N W+ + T Y GY T GK ++ + P
Sbjct: 98 DTTRLYDFNSY-----WRVHAGNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYS 152
Query: 157 WKEWVGLLKNSRFYNYTLCRNGVKEKHGS--------DYSKDYLTDLITNDSVSFFRTSK 208
W + ++ N CR E H + D + L D + + + K
Sbjct: 153 WSFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQ-AIQLLEK 211
Query: 209 KMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYA----PNPDKHWI--- 261
P + + + PH P ++ +L+P + + P P W+
Sbjct: 212 MKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIR 271
Query: 262 -------MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVY 314
+ + P PI ++F +++ ++ +D + + + L + ++T I +
Sbjct: 272 QREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAF 331
Query: 315 TADHGY 320
T+DHG+
Sbjct: 332 TSDHGF 337
>gi|53831991 steryl-sulfatase precursor [Homo sapiens]
Length = 583
Score = 53.9 bits (128), Expect = 6e-07
Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 15/117 (12%)
Query: 290 VDDSMETIYNMLVETGELDNTYIVYTADHGYHI-----------GQFGLVK-GKSMPYEF 337
+D S+ I N+L E ++T I +T+D G H+ G G+ K GK+ +E
Sbjct: 315 MDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEG 374
Query: 338 DIRVPFYVRGPNV-EAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLLD 391
IRVP +R P V +AG N+D+ PT+ +AG +P D +DG+ ++ LL+
Sbjct: 375 GIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLE 431
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Query: 43 RPNIILVLTDDQDVE----LGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTG 98
RPNIILV+ DD + G+ + + GG +P+C PSR++ +TG
Sbjct: 26 RPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTG 85
Query: 99 KYVHNHN----TYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144
+Y + T ++ S + TFA L GY TA GK+
Sbjct: 86 RYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKW 135
>gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo
sapiens]
Length = 502
Score = 52.0 bits (123), Expect = 2e-06
Identities = 82/368 (22%), Positives = 139/368 (37%), Gaps = 55/368 (14%)
Query: 45 NIILVLTDDQDVELGSMQ---VMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYV 101
N +L+L DD E G+ + + + F NAF + C PSR+S+LTG
Sbjct: 24 NALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQ 83
Query: 102 HNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWV 161
H + Y +++ + + + R+ + L+ G RT GK +V P E V
Sbjct: 84 HQNGMYGLHQDVH--HFNSFDKVRSLPLLLSQAGVRTGIIGK-------KHVGP---ETV 131
Query: 162 GLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVIS 221
+ YT NG + G + ++ L R + RP + ++
Sbjct: 132 YPFD----FAYTE-ENGSVLQVGRNITRIKL----------LVRKFLQTQDDRPFFLYVA 176
Query: 222 HAAPHGPEDSAPQYSRL---FPNASQHI--TPSYNYAPNPDKHWIMRYTGPMKPIHMEFT 276
PH S PQY F N + P + ++ Y P P
Sbjct: 177 FHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPA----A 232
Query: 277 NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYE 336
+ T+ +D + + L + G L++T +++T+D+G G++ Y
Sbjct: 233 RADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNG-----IPFPSGRTNLYW 287
Query: 337 FDIRVPFYVRGPN--VEAGCLNPHIVLNIDLAPTILDIAGLDIPA---------DMDGKS 385
P V P G ++ V +DL PTILD + P+ + G+S
Sbjct: 288 PGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRS 347
Query: 386 ILKLLDTE 393
+L L+ E
Sbjct: 348 LLPALEAE 355
>gi|31742482 arylsulfatase F precursor [Homo sapiens]
Length = 590
Score = 49.3 bits (116), Expect = 2e-05
Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 15/116 (12%)
Query: 290 VDDSMETIYNMLVETGELDNTYIVYTADHGYHI----------GQFGLVK-GKSM-PYEF 337
+D + I + + + G +NT + +T+DHG H+ G G+ K GK M +E
Sbjct: 318 MDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEG 377
Query: 338 DIRVPFYVRGP-NVEAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL 390
IRVP VR P V AG L +D+ PT+ ++G +P D +DG+ ++ LL
Sbjct: 378 GIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTVASVSGGSLPQDRVIDGRDLMPLL 433
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 14/113 (12%)
Query: 43 RPNIILVLTDDQDV-ELGSMQVMNKTRRI-----MEQGGAHFINAFVTTPMCCPSRSSIL 96
+PNI+L++ DD + +LG N T R + + G +C PSRS+ L
Sbjct: 29 KPNIVLIMVDDLGIGDLGCYG--NDTMRTPHIDRLAREGVRLTQHISAASLCSPSRSAFL 86
Query: 97 TGKYVHNHNTYTNN-----ENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144
TG+Y ++ +N + P+ +E+ T A L GY T GK+
Sbjct: 87 TGRYPIRSGMVSSGNRRVIQNLAVPAGLPLNET-TLAALLKKQGYSTGLIGKW 138
>gi|45430057 Arylsulfatase G [Homo sapiens]
Length = 525
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 40 RNIRPNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSI 95
R +PN +++L DD +LG+ K +++ G F++ C PSR+S+
Sbjct: 32 RGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASL 91
Query: 96 LTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVP 154
LTG+ + N T N +S +E+ T A L GY T GK+ ++GSY P
Sbjct: 92 LTGR-LGLRNGVTRNFAVTSVGGLPLNET-TLAEVLQQAGYVTGIIGKWHLGHHGSYHP 148
>gi|146229327 arylsulfatase A isoform b [Homo sapiens]
Length = 423
Score = 48.1 bits (113), Expect = 3e-05
Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 8/113 (7%)
Query: 286 TLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQFGLVK-GKSMPYEFD 338
+LM +D ++ T+ + + G L+ T +++TAD+G G GL++ GK YE
Sbjct: 166 SLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGG 225
Query: 339 IRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDGKSILKLL 390
+R P P A + + ++DL PT+ +AG +P +DG + LL
Sbjct: 226 VREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLL 278
>gi|58743319 arylsulfatase family, member H [Homo sapiens]
Length = 562
Score = 47.4 bits (111), Expect = 6e-05
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 9/114 (7%)
Query: 40 RNIRPNIILVLTDDQDVE----LGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSI 95
RN RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
Query: 96 LTGKY-VHNHNTYTNNENCS----SPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144
LTG+Y + + N N + S TFA L GYRT GK+
Sbjct: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
>gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens]
Length = 593
Score = 43.5 bits (101), Expect = 8e-04
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 15/109 (13%)
Query: 297 IYNMLVETGELDNTYIVYTADHGYHI----------GQFGLVK-GKSM-PYEFDIRVPFY 344
+ N + + G ++T+ +T+DHG H+ G G+ K GK M +E IRVP
Sbjct: 336 VLNAIEDNGLKNSTFTYFTSDHGGHLEARDGHSQLGGWNGIYKGGKGMGGWEGGIRVPGI 395
Query: 345 VRGPNV-EAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL 390
P V AG + +D+ PT++ + G ++P D +DG S++ LL
Sbjct: 396 FHWPGVLPAGRVIGEPTSLMDVFPTVVQLVGGEVPQDRVIDGHSLVPLL 444
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 14/113 (12%)
Query: 43 RPNIILVLTDDQDV-ELGSMQVMNKTRRI-----MEQGGAHFINAFVTTPMCCPSRSSIL 96
+PNI+L++ DD +LG N T R + + G P+C PSR++ L
Sbjct: 40 KPNILLIMADDLGTGDLGCYG--NNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFL 97
Query: 97 TGKYVHNHNTYTNNENCSSPSWQA-----QHESRTFAVYLNSTGYRTAFFGKY 144
TG++ +N + W A TFA L GY T GK+
Sbjct: 98 TGRHSFRSGMDASN-GYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKW 149
>gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens]
Length = 382
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 14/113 (12%)
Query: 43 RPNIILVLTDDQDV-ELGSMQVMNKTRRI-----MEQGGAHFINAFVTTPMCCPSRSSIL 96
+PNI+L++ DD +LG N T R + + G P+C PSR++ L
Sbjct: 40 KPNILLIMADDLGTGDLGCYG--NNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFL 97
Query: 97 TGKYVHNHNTYTNNENCSSPSWQA-----QHESRTFAVYLNSTGYRTAFFGKY 144
TG++ +N + W A TFA L GY T GK+
Sbjct: 98 TGRHSFRSGMDASN-GYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKW 149
>gi|157266309 arylsulfatase E precursor [Homo sapiens]
Length = 589
Score = 40.4 bits (93), Expect = 0.007
Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 15/109 (13%)
Query: 297 IYNMLVETGELDNTYIVYTADHGYHI----------GQFGLVKG-KSMP-YEFDIRVPFY 344
I + L G ++T I +T+DHG + G G+ KG K M +E IRVP
Sbjct: 333 ILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEGGIRVPGI 392
Query: 345 VRGPNV-EAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL 390
R P V AG + +D+ PT++ +AG ++P D +DG+ +L LL
Sbjct: 393 FRWPGVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQDRVIDGQDLLPLL 441
Score = 38.9 bits (89), Expect = 0.021
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 12/112 (10%)
Query: 43 RPNIILVLTDDQDV-ELG-----SMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSIL 96
RPNI+L++ DD + ++G +M+ N R + + G +C PSR++ L
Sbjct: 37 RPNILLLMADDLGIGDIGCYGNNTMRTPNIDR--LAEDGVKLTQHISAASLCTPSRAAFL 94
Query: 97 TGKYVHNHNTYTNNE----NCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144
TG+Y ++ + S TFA L GY T GK+
Sbjct: 95 TGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATGLIGKW 146
>gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo
sapiens]
Length = 685
Score = 32.3 bits (72), Expect = 1.9
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 631 IDHEIETLQNKIKNLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHRGSSLHPFRKGLQ 690
I+ E E + K++RE+ G+ +KK +E D + K + K SL R G+Q
Sbjct: 605 IEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSL---RLGMQ 661
Query: 691 EKDKVWLLREQKRKKKLRKLLKR 713
E + E++ +++ K LKR
Sbjct: 662 EDLEEMRREEEEMQRRRAKKLKR 684
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,348,968
Number of Sequences: 37866
Number of extensions: 1741466
Number of successful extensions: 4615
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 4505
Number of HSP's gapped (non-prelim): 68
length of query: 867
length of database: 18,247,518
effective HSP length: 111
effective length of query: 756
effective length of database: 14,044,392
effective search space: 10617560352
effective search space used: 10617560352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.