Guide to the Human Genome
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Search of human proteins with 239937451

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239937451 adenosylhomocysteinase isoform 2 [Homo sapiens]
         (404 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9951915 adenosylhomocysteinase isoform 1 [Homo sapiens]            823   0.0  
gi|239937451 adenosylhomocysteinase isoform 2 [Homo sapiens]          823   0.0  
gi|21361647 S-adenosylhomocysteine hydrolase-like 1 [Homo sapiens]    429   e-120
gi|195539349 S-adenosylhomocysteine hydrolase-like 2 isoform d [...   426   e-119
gi|195539347 S-adenosylhomocysteine hydrolase-like 2 isoform c [...   426   e-119
gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b [...   426   e-119
gi|24308043 S-adenosylhomocysteine hydrolase-like 2 isoform a [H...   426   e-119
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo...    36   0.054
gi|186928839 retinol dehydrogenase 12 [Homo sapiens]                   32   1.3  
gi|6912396 glyoxylate reductase/hydroxypyruvate reductase [Homo ...    31   1.7  
gi|229576906 F-box and WD repeat domain containing 12 isoform 3 ...    31   2.3  
gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ...    31   2.3  
gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens]              30   3.9  
gi|47157315 Janus kinase 3 [Homo sapiens]                              29   6.6  
gi|13375746 hypothetical protein LOC79624 [Homo sapiens]               29   6.6  

>gi|9951915 adenosylhomocysteinase isoform 1 [Homo sapiens]
          Length = 432

 Score =  823 bits (2127), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
           MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA
Sbjct: 29  MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 88

Query: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
           AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP
Sbjct: 89  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 148

Query: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
           GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD
Sbjct: 149 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 208

Query: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
           VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE
Sbjct: 209 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 268

Query: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
           GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY
Sbjct: 269 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 328

Query: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK 360
           RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK
Sbjct: 329 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK 388

Query: 361 KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
           KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
Sbjct: 389 KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 432


>gi|239937451 adenosylhomocysteinase isoform 2 [Homo sapiens]
          Length = 404

 Score =  823 bits (2127), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
           MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA
Sbjct: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60

Query: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
           AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP
Sbjct: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120

Query: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
           GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD
Sbjct: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180

Query: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
           VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE
Sbjct: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240

Query: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
           GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY
Sbjct: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300

Query: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK 360
           RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK
Sbjct: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK 360

Query: 361 KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
           KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
Sbjct: 361 KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404


>gi|21361647 S-adenosylhomocysteine hydrolase-like 1 [Homo sapiens]
          Length = 530

 Score =  429 bits (1104), Expect = e-120
 Identities = 209/405 (51%), Positives = 289/405 (71%), Gaps = 2/405 (0%)

Query: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
           M  L+ +R+R    KPL GA+I GC H+T +TAVLIETL  LGA+ +WS+CNI+STQ+  
Sbjct: 127 MSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEV 186

Query: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
           AAA+A+AG+ V+AWKGE+++++ WCI++ +       NMILDDGGDLT+ ++ KYP +  
Sbjct: 187 AAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFK 246

Query: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
            IRGI EE+ TGVH LY++   G L VPA+NVNDSVTK KFDNLY CRES++DG+KR TD
Sbjct: 247 KIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTD 306

Query: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
           VM  GK  VV GYG+VGKGC  AL+  GA V ITEIDPI ALQA M+G+ V  ++E  ++
Sbjct: 307 VMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQ 366

Query: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
            ++ +T TG  +++   H ++MK+  IVCN+GH + EIDV  L    +    ++ QVD  
Sbjct: 367 VDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHV 426

Query: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPD-KYPVGVHFLP 359
              +G+R++LLAEGRL+NL C+   P+FV+S + T Q +A IEL+  P+ +Y   V+ LP
Sbjct: 427 IWPDGKRVVLLAEGRLLNLSCST-VPTFVLSITATTQALALIELYNAPEGRYKQDVYLLP 485

Query: 360 KKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
           KK+DE VA  HL   +  LT+LT+ QA+YLG++ +GPFKP++YRY
Sbjct: 486 KKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY 530


>gi|195539349 S-adenosylhomocysteine hydrolase-like 2 isoform d
           [Homo sapiens]
          Length = 508

 Score =  426 bits (1094), Expect = e-119
 Identities = 206/405 (50%), Positives = 291/405 (71%), Gaps = 2/405 (0%)

Query: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
           MP LM +R+R    KPL GA+I GC H+T +TAVL+ETL  LGA+ +W++CNI+ST +  
Sbjct: 105 MPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEV 164

Query: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
           AAA+A++G PV+AWKGE+++++ WCI++ +  +    NMILDDGGDLT+ I+ KYP +  
Sbjct: 165 AAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFK 224

Query: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
            I+GI EE+ TGVH LY++   G L VPA+NVNDSVTK KFDNLY CRES++DG+KR TD
Sbjct: 225 KIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTD 284

Query: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
           +M  GK  VV GYG+VGKGC  AL+  G+ V +TEIDPI ALQA M+G+ +  ++E  ++
Sbjct: 285 MMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQ 344

Query: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
            +I +T TG  +++   H ++MK+  IVCN+GH + EIDV  L    +    ++ QVD  
Sbjct: 345 VDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHV 404

Query: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPD-KYPVGVHFLP 359
              +G+RI+LLAEGRL+NL C+   P+FV+S + T Q +A IEL+  P+ +Y   V+ LP
Sbjct: 405 IWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALALIELYNAPEGRYKQDVYLLP 463

Query: 360 KKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
           KK+DE VA  HL   +  LT+LT++QA+YLG++ +GPFKP++YRY
Sbjct: 464 KKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY 508


>gi|195539347 S-adenosylhomocysteine hydrolase-like 2 isoform c
           [Homo sapiens]
          Length = 509

 Score =  426 bits (1094), Expect = e-119
 Identities = 206/405 (50%), Positives = 291/405 (71%), Gaps = 2/405 (0%)

Query: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
           MP LM +R+R    KPL GA+I GC H+T +TAVL+ETL  LGA+ +W++CNI+ST +  
Sbjct: 106 MPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEV 165

Query: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
           AAA+A++G PV+AWKGE+++++ WCI++ +  +    NMILDDGGDLT+ I+ KYP +  
Sbjct: 166 AAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFK 225

Query: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
            I+GI EE+ TGVH LY++   G L VPA+NVNDSVTK KFDNLY CRES++DG+KR TD
Sbjct: 226 KIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTD 285

Query: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
           +M  GK  VV GYG+VGKGC  AL+  G+ V +TEIDPI ALQA M+G+ +  ++E  ++
Sbjct: 286 MMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQ 345

Query: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
            +I +T TG  +++   H ++MK+  IVCN+GH + EIDV  L    +    ++ QVD  
Sbjct: 346 VDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHV 405

Query: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPD-KYPVGVHFLP 359
              +G+RI+LLAEGRL+NL C+   P+FV+S + T Q +A IEL+  P+ +Y   V+ LP
Sbjct: 406 IWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALALIELYNAPEGRYKQDVYLLP 464

Query: 360 KKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
           KK+DE VA  HL   +  LT+LT++QA+YLG++ +GPFKP++YRY
Sbjct: 465 KKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY 509


>gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b
           [Homo sapiens]
          Length = 610

 Score =  426 bits (1094), Expect = e-119
 Identities = 206/405 (50%), Positives = 291/405 (71%), Gaps = 2/405 (0%)

Query: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
           MP LM +R+R    KPL GA+I GC H+T +TAVL+ETL  LGA+ +W++CNI+ST +  
Sbjct: 207 MPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEV 266

Query: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
           AAA+A++G PV+AWKGE+++++ WCI++ +  +    NMILDDGGDLT+ I+ KYP +  
Sbjct: 267 AAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFK 326

Query: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
            I+GI EE+ TGVH LY++   G L VPA+NVNDSVTK KFDNLY CRES++DG+KR TD
Sbjct: 327 KIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTD 386

Query: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
           +M  GK  VV GYG+VGKGC  AL+  G+ V +TEIDPI ALQA M+G+ +  ++E  ++
Sbjct: 387 MMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQ 446

Query: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
            +I +T TG  +++   H ++MK+  IVCN+GH + EIDV  L    +    ++ QVD  
Sbjct: 447 VDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHV 506

Query: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPD-KYPVGVHFLP 359
              +G+RI+LLAEGRL+NL C+   P+FV+S + T Q +A IEL+  P+ +Y   V+ LP
Sbjct: 507 IWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALALIELYNAPEGRYKQDVYLLP 565

Query: 360 KKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
           KK+DE VA  HL   +  LT+LT++QA+YLG++ +GPFKP++YRY
Sbjct: 566 KKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY 610


>gi|24308043 S-adenosylhomocysteine hydrolase-like 2 isoform a [Homo
           sapiens]
          Length = 611

 Score =  426 bits (1094), Expect = e-119
 Identities = 206/405 (50%), Positives = 291/405 (71%), Gaps = 2/405 (0%)

Query: 1   MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
           MP LM +R+R    KPL GA+I GC H+T +TAVL+ETL  LGA+ +W++CNI+ST +  
Sbjct: 208 MPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEV 267

Query: 61  AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
           AAA+A++G PV+AWKGE+++++ WCI++ +  +    NMILDDGGDLT+ I+ KYP +  
Sbjct: 268 AAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFK 327

Query: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
            I+GI EE+ TGVH LY++   G L VPA+NVNDSVTK KFDNLY CRES++DG+KR TD
Sbjct: 328 KIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTD 387

Query: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
           +M  GK  VV GYG+VGKGC  AL+  G+ V +TEIDPI ALQA M+G+ +  ++E  ++
Sbjct: 388 MMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQ 447

Query: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
            +I +T TG  +++   H ++MK+  IVCN+GH + EIDV  L    +    ++ QVD  
Sbjct: 448 VDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHV 507

Query: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPD-KYPVGVHFLP 359
              +G+RI+LLAEGRL+NL C+   P+FV+S + T Q +A IEL+  P+ +Y   V+ LP
Sbjct: 508 IWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALALIELYNAPEGRYKQDVYLLP 566

Query: 360 KKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
           KK+DE VA  HL   +  LT+LT++QA+YLG++ +GPFKP++YRY
Sbjct: 567 KKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY 611


>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
           sapiens]
          Length = 270

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 11/99 (11%)

Query: 178 ATDVMIAGKVAVVAGYG-DVGKGCAQALRGFGARVIITEIDPI--NALQAAMEGYEVTTM 234
           AT    AGKV VV G G  +G G  +A    GARV+I + D     AL+  + G  V  +
Sbjct: 2   ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFIL 60

Query: 235 DEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGH 273
            +  QE ++    +  I     R F ++  D +V N GH
Sbjct: 61  CDVTQEDDVKTLVSETI-----RRFGRL--DCVVNNAGH 92


>gi|186928839 retinol dehydrogenase 12 [Homo sapiens]
          Length = 316

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 168 RESLIDGIKRATDVMIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAM 226
           R+    G+ R T+V + GKV V+ G    +GK  A+ L   GARV I   D +    AA 
Sbjct: 23  RKFFAGGVCR-TNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAAS 81

Query: 227 E 227
           E
Sbjct: 82  E 82


>gi|6912396 glyoxylate reductase/hydroxypyruvate reductase [Homo
           sapiens]
          Length = 328

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 190 VAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVT-- 246
           + G G +G+  A+ L+ FG  R + T   P     A  +   V+T + A Q   I V   
Sbjct: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACS 217

Query: 247 -TTGCIDIILGRHFEQMKDDAIVCNIGHFDV 276
            T     +     F++MK+ A+  NI   DV
Sbjct: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDV 248


>gi|229576906 F-box and WD repeat domain containing 12 isoform 3
           [Homo sapiens]
          Length = 445

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 20/77 (25%)

Query: 53  IFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIH 112
           +++ QD  A A+     P Y            C+E  L  KDGP  M+ D  GD+     
Sbjct: 153 VWNCQDRDALAVLPMPQPCY------------CMEAYLT-KDGPFLMVGDAAGDI----- 194

Query: 113 TKYPQLLPGIRGISEET 129
             Y   LPG+R +S+ T
Sbjct: 195 --YTFTLPGLRDVSKVT 209


>gi|229576873 F-box and WD repeat domain containing 12 isoform 1
           [Homo sapiens]
          Length = 464

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 20/77 (25%)

Query: 53  IFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIH 112
           +++ QD  A A+     P Y            C+E  L  KDGP  M+ D  GD+     
Sbjct: 172 VWNCQDRDALAVLPMPQPCY------------CMEAYLT-KDGPFLMVGDAAGDI----- 213

Query: 113 TKYPQLLPGIRGISEET 129
             Y   LPG+R +S+ T
Sbjct: 214 --YTFTLPGLRDVSKVT 228


>gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens]
          Length = 244

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 5/60 (8%)

Query: 180 DVMIAGKVAVVAGYGD-VGKGCAQALRGFGARVII---TEIDPINALQAAMEGYEVTTMD 235
           ++ +AG+  +V G G  +G+G  QAL   GARV+    T+ D +++L     G E   +D
Sbjct: 2   ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD-LDSLVRECPGIEPVCVD 60


>gi|47157315 Janus kinase 3 [Homo sapiens]
          Length = 1124

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 19/66 (28%), Positives = 37/66 (56%), Gaps = 5/66 (7%)

Query: 123 RGISEETTTGVH--NLYKMMANGILKVPAINV--NDSVTKSKFDNLY-GCRESLIDGIKR 177
           RG S  T++ V   + Y++      K+PA ++  ++++    F  +Y GCR  ++DG  R
Sbjct: 490 RGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEAR 549

Query: 178 ATDVMI 183
            T+V++
Sbjct: 550 KTEVLL 555


>gi|13375746 hypothetical protein LOC79624 [Homo sapiens]
          Length = 441

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 13/37 (35%), Positives = 22/37 (59%)

Query: 136 LYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLI 172
           +Y+ +   I++ P I+  D   +SK  N YG +ES+I
Sbjct: 120 MYRRIHEAIIQSPPIDYFDVFKESKEQNFYGSQESII 156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,435,668
Number of Sequences: 37866
Number of extensions: 589589
Number of successful extensions: 1145
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1127
Number of HSP's gapped (non-prelim): 15
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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