Guide to the Human Genome
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Search of human proteins with 118918409

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118918409 transmembrane protein 69 [Homo sapiens]
         (247 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118918409 transmembrane protein 69 [Homo sapiens]                  496   e-141
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom...    30   1.5  
gi|224465202 synaptosomal-associated protein, 47kDa [Homo sapiens]     30   1.9  
gi|205830426 solute carrier family 39 (zinc transporter), member...    29   4.3  
gi|205830424 solute carrier family 39 (zinc transporter), member...    29   4.3  
gi|190360568 solute carrier family 39 (zinc transporter), member...    29   4.3  
gi|21361449 solute carrier family 2 (facilitated glucose transpo...    29   4.3  
gi|224994173 roundabout 1 isoform d [Homo sapiens]                     28   7.4  
gi|224994171 roundabout 1 isoform c [Homo sapiens]                     28   7.4  
gi|19743806 roundabout 1 isoform b [Homo sapiens]                      28   7.4  
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ...    28   7.4  
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ...    28   7.4  
gi|4506569 roundabout 1 isoform a [Homo sapiens]                       28   7.4  
gi|139394599 hypermethylated in cancer 2 [Homo sapiens]                28   7.4  
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]    28   9.6  

>gi|118918409 transmembrane protein 69 [Homo sapiens]
          Length = 247

 Score =  496 bits (1277), Expect = e-141
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 1   MLRFIQKFSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSK 60
           MLRFIQKFSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSK
Sbjct: 1   MLRFIQKFSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSK 60

Query: 61  TQCYHTSPCSFKKQQKQALLARPSSTITYLTDSPKPALCVTLAGLIPFVAPPLVMLMTKT 120
           TQCYHTSPCSFKKQQKQALLARPSSTITYLTDSPKPALCVTLAGLIPFVAPPLVMLMTKT
Sbjct: 61  TQCYHTSPCSFKKQQKQALLARPSSTITYLTDSPKPALCVTLAGLIPFVAPPLVMLMTKT 120

Query: 121 YIPILAFTQMAYGASFLSFLGGIRWGFALPEGSPAKPDYLNLASSAAPLFFSWFAFLISE 180
           YIPILAFTQMAYGASFLSFLGGIRWGFALPEGSPAKPDYLNLASSAAPLFFSWFAFLISE
Sbjct: 121 YIPILAFTQMAYGASFLSFLGGIRWGFALPEGSPAKPDYLNLASSAAPLFFSWFAFLISE 180

Query: 181 RLSEAIVTVIMGMGVAFHLELFLLPHYPNWFKALRIVVTLLATFSFIITLVVKSSFPEKG 240
           RLSEAIVTVIMGMGVAFHLELFLLPHYPNWFKALRIVVTLLATFSFIITLVVKSSFPEKG
Sbjct: 181 RLSEAIVTVIMGMGVAFHLELFLLPHYPNWFKALRIVVTLLATFSFIITLVVKSSFPEKG 240

Query: 241 HKRPGQV 247
           HKRPGQV
Sbjct: 241 HKRPGQV 247


>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
           sapiens]
          Length = 1352

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 44  PCPRPWLSSSFPAYMSKTQCYHTSPCSFKKQQKQALLARPSSTITYLTDSPKPALCVTLA 103
           PCP P  +S      + T+   +S     KQ    L+AR   T T ++  P P     L 
Sbjct: 72  PCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISKPPPP-----LE 126

Query: 104 GLIPFVAPP 112
             +PF+  P
Sbjct: 127 TSLPFLTIP 135


>gi|224465202 synaptosomal-associated protein, 47kDa [Homo
          sapiens]
          Length = 464

 Score = 30.0 bits (66), Expect = 1.9
 Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 5/52 (9%)

Query: 46 PRPWLSSSFPAYMSKTQCYHTSPCSF----KKQQKQALLARPSSTITYLTDS 93
          P PW + +    MS+  C HT PC++    K++     L+  S ++ ++TDS
Sbjct: 35 PGPWRTQT-QEQMSRDVCIHTWPCTYYLEPKRRWVTGQLSLTSLSLRFMTDS 85


>gi|205830426 solute carrier family 39 (zinc transporter), member 14
           isoform c [Homo sapiens]
          Length = 481

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 98  LCVTLAGLIPFVAPPLVMLMTKTYIP--ILAFTQMAYGASFLSFLGGIRWGFALPEGSPA 155
           LCVT+  L   +   +V  M KT+    +L F  +A G  + + L  +     +PE    
Sbjct: 159 LCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQL-----IPEAFGF 213

Query: 156 KPDYLNLASSAAPLFFSWFAFLISERLSEAIV 187
            P      S +A +F  ++ F  +E++ + ++
Sbjct: 214 NPLEDYYVSKSAVVFGGFYLFFFTEKILKILL 245


>gi|205830424 solute carrier family 39 (zinc transporter), member 14
           isoform a [Homo sapiens]
          Length = 492

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 98  LCVTLAGLIPFVAPPLVMLMTKTYIP--ILAFTQMAYGASFLSFLGGIRWGFALPEGSPA 155
           LCVT+  L   +   +V  M KT+    +L F  +A G  + + L  +     +PE    
Sbjct: 159 LCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQL-----IPEAFGF 213

Query: 156 KPDYLNLASSAAPLFFSWFAFLISERLSEAIV 187
            P      S +A +F  ++ F  +E++ + ++
Sbjct: 214 NPLEDYYVSKSAVVFGGFYLFFFTEKILKILL 245


>gi|190360568 solute carrier family 39 (zinc transporter), member 14
           isoform a [Homo sapiens]
          Length = 492

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 98  LCVTLAGLIPFVAPPLVMLMTKTYIP--ILAFTQMAYGASFLSFLGGIRWGFALPEGSPA 155
           LCVT+  L   +   +V  M KT+    +L F  +A G  + + L  +     +PE    
Sbjct: 159 LCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQL-----IPEAFGF 213

Query: 156 KPDYLNLASSAAPLFFSWFAFLISERLSEAIV 187
            P      S +A +F  ++ F  +E++ + ++
Sbjct: 214 NPLEDYYVSKSAVVFGGFYLFFFTEKILKILL 245


>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 3/49 (6%)

Query: 134 ASFLSFLGGIRWGFALPEGSPAKPDYLNLASSAAPL---FFSWFAFLIS 179
           A+F + LG + +GFAL   SPA P     A  A  L     SWF  +++
Sbjct: 29  AAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVT 77


>gi|224994173 roundabout 1 isoform d [Homo sapiens]
          Length = 1551

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 8/89 (8%)

Query: 8    FSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTS 67
            F+QA +   +Y+   GL+ +R  +         + S CPRP    S  + MS      T 
Sbjct: 1303 FAQAVAAAAEYA---GLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTR 1359

Query: 68   PCSFKKQQKQALLARPSSTITYLTDSPKP 96
            P    K Q   L        TY  D P P
Sbjct: 1360 PAKKLKHQPGHLRRE-----TYTDDLPPP 1383


>gi|224994171 roundabout 1 isoform c [Homo sapiens]
          Length = 1606

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 8/89 (8%)

Query: 8    FSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTS 67
            F+QA +   +Y+   GL+ +R  +         + S CPRP    S  + MS      T 
Sbjct: 1358 FAQAVAAAAEYA---GLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTR 1414

Query: 68   PCSFKKQQKQALLARPSSTITYLTDSPKP 96
            P    K Q   L        TY  D P P
Sbjct: 1415 PAKKLKHQPGHLRRE-----TYTDDLPPP 1438


>gi|19743806 roundabout 1 isoform b [Homo sapiens]
          Length = 1612

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 8/89 (8%)

Query: 8    FSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTS 67
            F+QA +   +Y+   GL+ +R  +         + S CPRP    S  + MS      T 
Sbjct: 1364 FAQAVAAAAEYA---GLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTR 1420

Query: 68   PCSFKKQQKQALLARPSSTITYLTDSPKP 96
            P    K Q   L        TY  D P P
Sbjct: 1421 PAKKLKHQPGHLRRE-----TYTDDLPPP 1444


>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
            sapiens]
          Length = 1562

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 8/89 (8%)

Query: 8    FSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTS 67
            F+QA +   +Y+   GL+ +R  +         + S CPRP    S  + MS      T 
Sbjct: 1314 FAQAVAAAAEYA---GLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTR 1370

Query: 68   PCSFKKQQKQALLARPSSTITYLTDSPKP 96
            P    K Q   L        TY  D P P
Sbjct: 1371 PAKKLKHQPGHLRRE-----TYTDDLPPP 1394


>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
            sapiens]
          Length = 1615

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 8/89 (8%)

Query: 8    FSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTS 67
            F+QA +   +Y+   GL+ +R  +         + S CPRP    S  + MS      T 
Sbjct: 1367 FAQAVAAAAEYA---GLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTR 1423

Query: 68   PCSFKKQQKQALLARPSSTITYLTDSPKP 96
            P    K Q   L        TY  D P P
Sbjct: 1424 PAKKLKHQPGHLRRE-----TYTDDLPPP 1447


>gi|4506569 roundabout 1 isoform a [Homo sapiens]
          Length = 1651

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 8/89 (8%)

Query: 8    FSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTS 67
            F+QA +   +Y+   GL+ +R  +         + S CPRP    S  + MS      T 
Sbjct: 1403 FAQAVAAAAEYA---GLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTR 1459

Query: 68   PCSFKKQQKQALLARPSSTITYLTDSPKP 96
            P    K Q   L        TY  D P P
Sbjct: 1460 PAKKLKHQPGHLRRE-----TYTDDLPPP 1483


>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
          Length = 615

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 18/58 (31%), Positives = 25/58 (43%)

Query: 128 TQMAYGASFLSFLGGIRWGFALPEGSPAKPDYLNLASSAAPLFFSWFAFLISERLSEA 185
           T M     F   L  I  G  LP   PA+P++  L ++A+ L     A L   +L  A
Sbjct: 85  TDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLLTAASYLQLPELAALCRRKLKRA 142


>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
          Length = 1597

 Score = 27.7 bits (60), Expect = 9.6
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 8/50 (16%)

Query: 27  SRTDILSLKMSLQQNFS--------PCPRPWLSSSFPAYMSKTQCYHTSP 68
           S T + +LK   Q++ S        P  +PW+S   PA+ +++  Y +SP
Sbjct: 662 SPTALSTLKQDSQESISNLERPSSPPSIQPWVSPHNPAFATESPAYGSSP 711


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.137    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,136,668
Number of Sequences: 37866
Number of extensions: 383767
Number of successful extensions: 1150
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1147
Number of HSP's gapped (non-prelim): 15
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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