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Search of human proteins with 239753890
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239753890 PREDICTED: similar to kelch-like 2, Mayven
(Drosophila) [Homo sapiens]
(211 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239753890 PREDICTED: similar to kelch-like 2, Mayven (Drosoph... 440 e-124
gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens] 307 4e-84
gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens] 305 1e-83
gi|166235129 kelch-like 3 [Homo sapiens] 204 6e-53
gi|239835724 kelch-like 2, Mayven isoform 3 [Homo sapiens] 140 8e-34
gi|38194229 kelch-like 17 [Homo sapiens] 127 5e-30
gi|40807500 kelch-like 20 [Homo sapiens] 124 6e-29
gi|11056006 kelch-like 12 [Homo sapiens] 121 5e-28
gi|55770880 kelch-like 5 isoform 3 [Homo sapiens] 107 1e-23
gi|65289292 kelch-like 5 isoform 1 [Homo sapiens] 107 1e-23
gi|55925604 kelch-like 18 [Homo sapiens] 102 2e-22
gi|17017980 kelch-like 4 isoform 2 [Homo sapiens] 101 5e-22
gi|17017982 kelch-like 4 isoform 1 [Homo sapiens] 101 5e-22
gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens] 100 1e-21
gi|40018614 DRE1 protein [Homo sapiens] 96 2e-20
gi|14780904 kelch-like 1 protein [Homo sapiens] 94 6e-20
gi|5174473 intracisternal A particle-promoted polypeptide isofor... 92 2e-19
gi|223890235 intracisternal A particle-promoted polypeptide isof... 92 2e-19
gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo... 91 5e-19
gi|148664209 kelch-like 10 [Homo sapiens] 90 1e-18
gi|109150407 kelch-like 6 [Homo sapiens] 88 5e-18
gi|34101268 kelch-like 8 [Homo sapiens] 88 6e-18
gi|170784846 kelch-like 7 isoform 1 [Homo sapiens] 86 2e-17
gi|45269145 kelch-like ECH-associated protein 1 [Homo sapiens] 86 2e-17
gi|22027642 kelch-like ECH-associated protein 1 [Homo sapiens] 86 2e-17
gi|55925608 kelch-like 21 [Homo sapiens] 86 2e-17
gi|194097389 kelch-like 38 [Homo sapiens] 84 9e-17
gi|65289632 kelch-like 5 isoform 2 [Homo sapiens] 82 3e-16
gi|128485503 kelch-like 30 [Homo sapiens] 81 6e-16
gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Hom... 81 7e-16
>gi|239753890 PREDICTED: similar to kelch-like 2, Mayven
(Drosophila) [Homo sapiens]
Length = 211
Score = 440 bits (1132), Expect = e-124
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MAVPLVTLLCTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTI 60
MAVPLVTLLCTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTI
Sbjct: 1 MAVPLVTLLCTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTI 60
Query: 61 VAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQ 120
VAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQ
Sbjct: 61 VAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQ 120
Query: 121 VTEENTCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAGKWSRPQLNLGGNCLVFD 180
VTEENTCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAGKWSRPQLNLGGNCLVFD
Sbjct: 121 VTEENTCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAGKWSRPQLNLGGNCLVFD 180
Query: 181 MILQWSLESHVIFLDLGFKNIHLKSYNGHTA 211
MILQWSLESHVIFLDLGFKNIHLKSYNGHTA
Sbjct: 181 MILQWSLESHVIFLDLGFKNIHLKSYNGHTA 211
>gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens]
Length = 597
Score = 307 bits (787), Expect = 4e-84
Identities = 153/180 (85%), Positives = 155/180 (86%), Gaps = 19/180 (10%)
Query: 2 AVPLVTLLCTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIV 61
A P + +CTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIV
Sbjct: 6 ARPQILFVCTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIV 65
Query: 62 AEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQV 121
AEDMEISAHRVVLAACSPYFHAMFTG MSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQV
Sbjct: 66 AEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQV 125
Query: 122 TEENT-------------------CEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYA 162
TEEN CEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYA
Sbjct: 126 TEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYA 185
>gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens]
Length = 593
Score = 305 bits (782), Expect = 1e-83
Identities = 153/181 (84%), Positives = 154/181 (85%), Gaps = 19/181 (10%)
Query: 1 MAVPLVTLLCTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTI 60
M P + CTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTI
Sbjct: 1 METPPLPPACTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTI 60
Query: 61 VAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQ 120
VAEDMEISAHRVVLAACSPYFHAMFTG MSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQ
Sbjct: 61 VAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQ 120
Query: 121 VTEENT-------------------CEFLESQLHPVNCLGIRAFADMHACTDLLNKANTY 161
VTEEN CEFLESQLHPVNCLGIRAFADMHACTDLLNKANTY
Sbjct: 121 VTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTY 180
Query: 162 A 162
A
Sbjct: 181 A 181
>gi|166235129 kelch-like 3 [Homo sapiens]
Length = 587
Score = 204 bits (518), Expect = 6e-53
Identities = 106/169 (62%), Positives = 124/169 (73%), Gaps = 20/169 (11%)
Query: 24 DNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHA 83
D+ + +TVNP HM KAFKVMNELRS+ LLCDV IVAED+EI AHRVVLAACSPYF A
Sbjct: 18 DDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCA 77
Query: 84 MFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENT----------------- 126
MFTG MSES+AK++ IK+VDG TL LIDY+YTAEI+VTEEN
Sbjct: 78 MFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQ 137
Query: 127 --CEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAGKWSRPQLNLG 173
C+FL+SQLHP NCLGIRAFAD+H CTDLL +AN YA + P++ LG
Sbjct: 138 NCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYA-EQHFPEVMLG 185
>gi|239835724 kelch-like 2, Mayven isoform 3 [Homo sapiens]
Length = 505
Score = 140 bits (353), Expect = 8e-34
Identities = 73/93 (78%), Positives = 73/93 (78%), Gaps = 19/93 (20%)
Query: 89 MSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEF 129
MSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEEN CEF
Sbjct: 1 MSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEF 60
Query: 130 LESQLHPVNCLGIRAFADMHACTDLLNKANTYA 162
LESQLHPVNCLGIRAFADMHACTDLLNKANTYA
Sbjct: 61 LESQLHPVNCLGIRAFADMHACTDLLNKANTYA 93
>gi|38194229 kelch-like 17 [Homo sapiens]
Length = 642
Score = 127 bits (320), Expect = 5e-30
Identities = 67/143 (46%), Positives = 83/143 (58%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H AF M+ +R + LLCD+ + EI AH+VVLA+CSPYFHAMFT MSESR V
Sbjct: 74 HYHDAFVAMSRMRQRGLLCDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESRQTHV 133
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVN 138
+ ++D L L+ + YTAEI V E N C+FL SQL P N
Sbjct: 134 TLHDIDPQALDQLVQFAYTAEIVVGEGNVQTLLPAASLLQLNGVRDACCKFLLSQLDPSN 193
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
CLGIR FAD H+C+DLL A+ Y
Sbjct: 194 CLGIRGFADAHSCSDLLKAAHRY 216
>gi|40807500 kelch-like 20 [Homo sapiens]
Length = 609
Score = 124 bits (311), Expect = 6e-29
Identities = 64/143 (44%), Positives = 87/143 (60%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H ++ +V+N LR LCDV +V +I AHRV+L+ACSPYF AMFTG ++ESR V
Sbjct: 50 HPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEV 109
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVN 138
I+++D + +LID+ YT++I V E N CEFL+ QL P N
Sbjct: 110 VIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSN 169
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
CLGIRAFAD H+C +LL A+ +
Sbjct: 170 CLGIRAFADTHSCRELLRIADKF 192
>gi|11056006 kelch-like 12 [Homo sapiens]
Length = 568
Score = 121 bits (303), Expect = 5e-28
Identities = 65/146 (44%), Positives = 80/146 (54%), Gaps = 19/146 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H K MN LR N LCDVT+ E + AHR+VLAACS YF AMFT +SE V
Sbjct: 15 HAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYV 74
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVN 138
I+ + T+ +L+D+VYT + VT EN CEFLESQL P N
Sbjct: 75 DIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSN 134
Query: 139 CLGIRAFADMHACTDLLNKANTYAGK 164
CLGIR FA+ H C DL+ A ++ K
Sbjct: 135 CLGIRDFAETHNCVDLMQAAEVFSQK 160
>gi|55770880 kelch-like 5 isoform 3 [Homo sapiens]
Length = 709
Score = 107 bits (266), Expect = 1e-23
Identities = 57/143 (39%), Positives = 79/143 (55%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H ++ FK M LCDV +VA D I AHR+VL++ S YF AMFT + E+R + +
Sbjct: 156 HAEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREARQEEI 215
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEEN-------------------TCEFLESQLHPVN 138
+++ V+ +L LI Y YT +++ E+N C+FL QLHP N
Sbjct: 216 KMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPSN 275
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
CLGIR+FAD CTDL A+ Y
Sbjct: 276 CLGIRSFADAQGCTDLHKVAHNY 298
>gi|65289292 kelch-like 5 isoform 1 [Homo sapiens]
Length = 755
Score = 107 bits (266), Expect = 1e-23
Identities = 57/143 (39%), Positives = 79/143 (55%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H ++ FK M LCDV +VA D I AHR+VL++ S YF AMFT + E+R + +
Sbjct: 202 HAEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREARQEEI 261
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEEN-------------------TCEFLESQLHPVN 138
+++ V+ +L LI Y YT +++ E+N C+FL QLHP N
Sbjct: 262 KMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPSN 321
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
CLGIR+FAD CTDL A+ Y
Sbjct: 322 CLGIRSFADAQGCTDLHKVAHNY 344
>gi|55925604 kelch-like 18 [Homo sapiens]
Length = 574
Score = 102 bits (254), Expect = 2e-22
Identities = 52/140 (37%), Positives = 75/140 (53%), Gaps = 19/140 (13%)
Query: 41 KAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIK 100
+ + VM E+R Q LCDVT+ D + SAHR+VLAA PYFHAMFT M E + + ++
Sbjct: 23 RGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQ 82
Query: 101 EVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVNCLG 141
+D L LI++ Y + + ++N C FL +LHP NCLG
Sbjct: 83 GMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLG 142
Query: 142 IRAFADMHACTDLLNKANTY 161
+R FA+ C L + AN++
Sbjct: 143 VRQFAETMMCAVLYDAANSF 162
>gi|17017980 kelch-like 4 isoform 2 [Homo sapiens]
Length = 720
Score = 101 bits (251), Expect = 5e-22
Identities = 55/143 (38%), Positives = 78/143 (54%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H ++ + M + LCDV ++A + I AHR+VL+A S YF AMFT + E++ + V
Sbjct: 164 HAEQTLRKMENYLKEKQLCDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAKQEEV 223
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEE------------------NTC-EFLESQLHPVN 138
R++ VD L L+ Y YT +Q+ E+ + C FL QLHP N
Sbjct: 224 RMEGVDPNALNSLVQYAYTGVLQLKEDTIESLLAAACLLQLTQVIDVCSNFLIKQLHPSN 283
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
CLGIR+F D CT+LLN A+ Y
Sbjct: 284 CLGIRSFGDAQGCTELLNVAHKY 306
>gi|17017982 kelch-like 4 isoform 1 [Homo sapiens]
Length = 718
Score = 101 bits (251), Expect = 5e-22
Identities = 55/143 (38%), Positives = 78/143 (54%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H ++ + M + LCDV ++A + I AHR+VL+A S YF AMFT + E++ + V
Sbjct: 164 HAEQTLRKMENYLKEKQLCDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAKQEEV 223
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEE------------------NTC-EFLESQLHPVN 138
R++ VD L L+ Y YT +Q+ E+ + C FL QLHP N
Sbjct: 224 RMEGVDPNALNSLVQYAYTGVLQLKEDTIESLLAAACLLQLTQVIDVCSNFLIKQLHPSN 283
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
CLGIR+F D CT+LLN A+ Y
Sbjct: 284 CLGIRSFGDAQGCTELLNVAHKY 306
>gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens]
Length = 571
Score = 100 bits (248), Expect = 1e-21
Identities = 51/143 (35%), Positives = 77/143 (53%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H ++ + +N LR + LCD+ + D++I AH+VVLA+ SPYF AMFTG +SE V
Sbjct: 17 HSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASVSPYFKAMFTGNLSEKENSEV 76
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVN 138
+ +D L+ +++Y YT + ++++ C FLESQL P N
Sbjct: 77 EFQCIDETALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVLKECCAFLESQLDPGN 136
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
C+GI FA+ + C DL A Y
Sbjct: 137 CIGISRFAETYGCRDLYLAATKY 159
>gi|40018614 DRE1 protein [Homo sapiens]
Length = 600
Score = 95.9 bits (237), Expect = 2e-20
Identities = 52/144 (36%), Positives = 67/144 (46%), Gaps = 19/144 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H + ++ NE R L DV I E E HR VL+ACS YF AMF ESR V
Sbjct: 48 HAENILQIFNEFRDSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLV 107
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVN 138
I + + + YVYT ++++T EN +FLE QL P N
Sbjct: 108 EINGILAEAMECFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCN 167
Query: 139 CLGIRAFADMHACTDLLNKANTYA 162
CLGI+ FAD H+ L K +A
Sbjct: 168 CLGIQRFADTHSLKTLFTKCKNFA 191
>gi|14780904 kelch-like 1 protein [Homo sapiens]
Length = 748
Score = 94.4 bits (233), Expect = 6e-20
Identities = 49/143 (34%), Positives = 77/143 (53%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H ++ F+ M Q LCDV ++ + +I AHR+VL++ S YF AMFT + E++ + +
Sbjct: 194 HAEQTFRKMESYLKQQQLCDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAKQEEI 253
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTE-------------------ENTCEFLESQLHPVN 138
+++ +D L L+ + YT +++ E E C FL LHP N
Sbjct: 254 KMEGIDPNALWDLVQFAYTGCLELKEDTIENLLAAACLLQLPQVVEVCCHFLMKLLHPSN 313
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
CLGIRAFAD C +L+ A++Y
Sbjct: 314 CLGIRAFADAQGCIELMKVAHSY 336
>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
[Homo sapiens]
Length = 584
Score = 92.4 bits (228), Expect = 2e-19
Identities = 49/143 (34%), Positives = 73/143 (51%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H + +N++R+ CDV + AHR+VLAA SPYF A+FTGGM ES V
Sbjct: 19 HAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVV 78
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVN 138
I ++ ++L+D++YT + + N CEFL+ Q+ P+N
Sbjct: 79 PILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQIDPLN 138
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
C+GI F++ AC DLL + Y
Sbjct: 139 CIGIFQFSEQIACHDLLEFSENY 161
>gi|223890235 intracisternal A particle-promoted polypeptide isoform
2 [Homo sapiens]
Length = 582
Score = 92.4 bits (228), Expect = 2e-19
Identities = 49/143 (34%), Positives = 73/143 (51%), Gaps = 19/143 (13%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRV 97
H + +N++R+ CDV + AHR+VLAA SPYF A+FTGGM ES V
Sbjct: 19 HAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVV 78
Query: 98 RIKEVDGWTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVN 138
I ++ ++L+D++YT + + N CEFL+ Q+ P+N
Sbjct: 79 PILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQIDPLN 138
Query: 139 CLGIRAFADMHACTDLLNKANTY 161
C+GI F++ AC DLL + Y
Sbjct: 139 CIGIFQFSEQIACHDLLEFSENY 161
>gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo
sapiens]
Length = 589
Score = 91.3 bits (225), Expect = 5e-19
Identities = 50/129 (38%), Positives = 65/129 (50%), Gaps = 20/129 (15%)
Query: 46 MNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRI-KEVDG 104
+N LR Q L DV + A + HR VLAACS YF AMF+GG+ ES+ V +
Sbjct: 36 LNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHP 95
Query: 105 WTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVNCLGIRAF 145
L +L+DY Y++ + + EEN EFLE LHP NCLG+
Sbjct: 96 EVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLL 155
Query: 146 ADMHACTDL 154
+D H CT L
Sbjct: 156 SDAHQCTKL 164
>gi|148664209 kelch-like 10 [Homo sapiens]
Length = 608
Score = 90.1 bits (222), Expect = 1e-18
Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 30/164 (18%)
Query: 19 LDSKDDNTEKHCPVTVNPWHMKK-----AFKVMNELRSQNLLCDVTIVAEDMEISAHRVV 73
++S +T H P HM++ A ++ NELR + LCDV I E SAH+ +
Sbjct: 3 MESAAASTRFHQP------HMERKMSAMACEIFNELRLEGKLCDVVIKVNGFEFSAHKNI 56
Query: 74 LAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENT------- 126
L +CS YF A+FT G + + K I + ++++I+Y YT + +T +N
Sbjct: 57 LCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAA 116
Query: 127 ------------CEFLESQLHPVNCLGIRAFADMHACTDLLNKA 158
CEFL+S+L NC+GI F D + C +L KA
Sbjct: 117 DQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKA 160
>gi|109150407 kelch-like 6 [Homo sapiens]
Length = 621
Score = 88.2 bits (217), Expect = 5e-18
Identities = 49/135 (36%), Positives = 67/135 (49%), Gaps = 19/135 (14%)
Query: 46 MNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGW 105
+ LR +N L DV + + E S HRVVLAA S YF AMF + E KR+ IK VD
Sbjct: 62 LETLRMENALTDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRIIIKGVDAE 121
Query: 106 TLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVNCLGIRAFA 146
T+ L+DY YT++ +T++N FL L+P NC+GI A
Sbjct: 122 TMHTLLDYTYTSKALITKQNVQRVLEAANLFQFLRMVDACASFLTEALNPENCVGILRLA 181
Query: 147 DMHACTDLLNKANTY 161
D H+ L + +Y
Sbjct: 182 DTHSLDSLKKQVQSY 196
>gi|34101268 kelch-like 8 [Homo sapiens]
Length = 620
Score = 87.8 bits (216), Expect = 6e-18
Identities = 44/127 (34%), Positives = 69/127 (54%), Gaps = 19/127 (14%)
Query: 55 LCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYV 114
LCDVT+ IS H++VLA PYF AMF M+E++ + I++ DG + L+ +V
Sbjct: 66 LCDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFV 125
Query: 115 YTAEIQVTEENT-------------------CEFLESQLHPVNCLGIRAFADMHACTDLL 155
Y++ + +T +N CE+++ HP NCL +RAFA+ H DL+
Sbjct: 126 YSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRIDLM 185
Query: 156 NKANTYA 162
+ A+ YA
Sbjct: 186 DMADQYA 192
>gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]
Length = 586
Score = 86.3 bits (212), Expect = 2e-17
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 19/136 (13%)
Query: 45 VMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDG 104
VMN +R Q LCDV ++ ++ +I AHRVVLAA S +F+ MFT M ES++ V +K+ +
Sbjct: 33 VMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEP 92
Query: 105 WTLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVNCLGIRAF 145
+ L+++ YTA I V N +FL+ Q+ NCLGI
Sbjct: 93 DIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVL 152
Query: 146 ADMHACTDLLNKANTY 161
A+ C +L A+ +
Sbjct: 153 AECLDCPELKATADDF 168
>gi|45269145 kelch-like ECH-associated protein 1 [Homo sapiens]
Length = 624
Score = 85.9 bits (211), Expect = 2e-17
Identities = 54/148 (36%), Positives = 74/148 (50%), Gaps = 24/148 (16%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIV-----AEDMEISAHRVVLAACSPYFHAMFTGGMSES 92
H K+AF +MNELR LCDVT+ A + AH+VVLA+ SP F AMFT G+ E
Sbjct: 59 HTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQ 118
Query: 93 RAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEE------------------NTC-EFLESQ 133
+ V I+ + + LI++ YTA I + E+ C +FL Q
Sbjct: 119 GMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQ 178
Query: 134 LHPVNCLGIRAFADMHACTDLLNKANTY 161
L P N +GI FA+ C +L +A Y
Sbjct: 179 LDPSNAIGIANFAEQIGCVELHQRAREY 206
>gi|22027642 kelch-like ECH-associated protein 1 [Homo sapiens]
Length = 624
Score = 85.9 bits (211), Expect = 2e-17
Identities = 54/148 (36%), Positives = 74/148 (50%), Gaps = 24/148 (16%)
Query: 38 HMKKAFKVMNELRSQNLLCDVTIV-----AEDMEISAHRVVLAACSPYFHAMFTGGMSES 92
H K+AF +MNELR LCDVT+ A + AH+VVLA+ SP F AMFT G+ E
Sbjct: 59 HTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQ 118
Query: 93 RAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEE------------------NTC-EFLESQ 133
+ V I+ + + LI++ YTA I + E+ C +FL Q
Sbjct: 119 GMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQ 178
Query: 134 LHPVNCLGIRAFADMHACTDLLNKANTY 161
L P N +GI FA+ C +L +A Y
Sbjct: 179 LDPSNAIGIANFAEQIGCVELHQRAREY 206
>gi|55925608 kelch-like 21 [Homo sapiens]
Length = 597
Score = 85.9 bits (211), Expect = 2e-17
Identities = 54/159 (33%), Positives = 83/159 (52%), Gaps = 24/159 (15%)
Query: 27 EKHCPVTVNPW----HMKKAFKVMNELRSQNLLCDVTI-VAEDMEISAHRVVLAACSPYF 81
E+ P+ V P+ H + +++LR++ DVT+ A + AHR VLAA SPYF
Sbjct: 2 ERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYF 61
Query: 82 HAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEEN---------------- 125
AMF G + ESRA+RVR+ V L++L+D+ YT + V+ +N
Sbjct: 62 RAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQFPAV 121
Query: 126 --TC-EFLESQLHPVNCLGIRAFADMHACTDLLNKANTY 161
C FL+ QL NCL ++ FA+ +C+ L + A +
Sbjct: 122 KEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRF 160
>gi|194097389 kelch-like 38 [Homo sapiens]
Length = 581
Score = 84.0 bits (206), Expect = 9e-17
Identities = 48/136 (35%), Positives = 67/136 (49%), Gaps = 19/136 (13%)
Query: 46 MNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGW 105
+N LR +L DV+I A EI HR VLA+ SPYF AMF E +V++K +D
Sbjct: 24 LNSLRQSRILTDVSICAGAREIPCHRNVLASSSPYFRAMFCSSFREKSEAKVQLKGIDPP 83
Query: 106 TLRMLIDYVYTAEIQVTEENT-------------------CEFLESQLHPVNCLGIRAFA 146
TL ++ YVYT E + +N +L+SQL P NCLG+ +
Sbjct: 84 TLDQIVSYVYTGEAHIATDNVLPVMEAASMLQFPKLFEACSSYLQSQLAPSNCLGMIRLS 143
Query: 147 DMHACTDLLNKANTYA 162
++ +C L KA A
Sbjct: 144 EILSCETLKKKAREVA 159
>gi|65289632 kelch-like 5 isoform 2 [Homo sapiens]
Length = 694
Score = 82.4 bits (202), Expect = 3e-16
Identities = 44/117 (37%), Positives = 66/117 (56%), Gaps = 19/117 (16%)
Query: 64 DMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTE 123
+ + S+ R+VL++ S YF AMFT + E+R + ++++ V+ +L LI Y YT +++ E
Sbjct: 167 ESDSSSCRLVLSSVSDYFAAMFTNDVREARQEEIKMEGVEPNSLWSLIQYAYTGRLELKE 226
Query: 124 ENT-------------------CEFLESQLHPVNCLGIRAFADMHACTDLLNKANTY 161
+N C+FL QLHP NCLGIR+FAD CTDL A+ Y
Sbjct: 227 DNIECLLSTACLLQLSQVVEACCKFLMKQLHPSNCLGIRSFADAQGCTDLHKVAHNY 283
>gi|128485503 kelch-like 30 [Homo sapiens]
Length = 560
Score = 81.3 bits (199), Expect = 6e-16
Identities = 46/132 (34%), Positives = 67/132 (50%), Gaps = 19/132 (14%)
Query: 46 MNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGW 105
+ LRSQ L DVT++ E+ HR +LA SPYFHAMF G +ES + RV +++V+
Sbjct: 5 LQRLRSQPKLADVTLLVGGRELPCHRGLLALSSPYFHAMFAGDFAESFSARVELRDVEPA 64
Query: 106 TLRMLIDYVYTAEIQVTEEN------------------TC-EFLESQLHPVNCLGIRAFA 146
+ L+D+VYT + +T+ N C +L+ QL NCLGI F
Sbjct: 65 VVGQLVDFVYTGRLTITQGNVEALTRTAARLHFPSVQKVCGRYLQQQLDAANCLGICEFG 124
Query: 147 DMHACTDLLNKA 158
+ + KA
Sbjct: 125 EQQGLLGVAAKA 136
>gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Homo
sapiens]
Length = 623
Score = 80.9 bits (198), Expect = 7e-16
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 19/126 (15%)
Query: 52 QNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGGMSESRAKRVRIKEVDGWTLRMLI 111
Q L D+ ++ E E H++VLA CS YF AMF G+SES+ V ++ VD TL+++I
Sbjct: 27 QQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIII 86
Query: 112 DYVYTAEIQVTE-------ENTC------------EFLESQLHPVNCLGIRAFADMHACT 152
Y YT + + + E C E+L +++ NC+ + +FAD+ +C
Sbjct: 87 TYAYTGNLAMNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCE 146
Query: 153 DLLNKA 158
+L A
Sbjct: 147 ELKQSA 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,764,696
Number of Sequences: 37866
Number of extensions: 297447
Number of successful extensions: 784
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 532
Number of HSP's gapped (non-prelim): 186
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.