Guide to the Human Genome
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Search of human proteins with 239753676

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753676 PREDICTED: hypothetical protein [Homo sapiens]
         (194 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753676 PREDICTED: hypothetical protein [Homo sapiens]           405   e-114
gi|239748302 PREDICTED: hypothetical protein [Homo sapiens]           405   e-114
gi|239742200 PREDICTED: hypothetical protein [Homo sapiens]           405   e-114
gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]     33   0.15 
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [...    32   0.44 
gi|166795252 hypothetical protein LOC23359 [Homo sapiens]              30   0.99 
gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide...    29   2.2  
gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens]      29   2.2  
gi|157671931 solute carrier family 5 (sodium/glucose cotransport...    28   3.7  
gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo sa...    28   4.9  
gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo s...    28   4.9  
gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]     28   4.9  
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]          28   4.9  
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ...    27   8.4  
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [...    27   8.4  

>gi|239753676 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 194

 Score =  405 bits (1042), Expect = e-114
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL 60
           MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL
Sbjct: 1   MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL 60

Query: 61  LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY 120
           LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY
Sbjct: 61  LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY 120

Query: 121 AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI 180
           AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI
Sbjct: 121 AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI 180

Query: 181 NMQLPAGNPNPFSP 194
           NMQLPAGNPNPFSP
Sbjct: 181 NMQLPAGNPNPFSP 194


>gi|239748302 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 194

 Score =  405 bits (1042), Expect = e-114
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL 60
           MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL
Sbjct: 1   MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL 60

Query: 61  LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY 120
           LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY
Sbjct: 61  LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY 120

Query: 121 AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI 180
           AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI
Sbjct: 121 AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI 180

Query: 181 NMQLPAGNPNPFSP 194
           NMQLPAGNPNPFSP
Sbjct: 181 NMQLPAGNPNPFSP 194


>gi|239742200 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 194

 Score =  405 bits (1042), Expect = e-114
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL 60
           MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL
Sbjct: 1   MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVL 60

Query: 61  LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY 120
           LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY
Sbjct: 61  LLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYLGY 120

Query: 121 AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI 180
           AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI
Sbjct: 121 AVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHI 180

Query: 181 NMQLPAGNPNPFSP 194
           NMQLPAGNPNPFSP
Sbjct: 181 NMQLPAGNPNPFSP 194


>gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]
          Length = 209

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 27/128 (21%), Positives = 54/128 (42%), Gaps = 15/128 (11%)

Query: 48  IWNGALAITTGVLLLLA----YREWTQRYLGEATFTFVI---LSIMGCPLHFAIALESAL 100
           +W G L + T  +L+      Y  +++  L  +  T ++   L+++G  + F  +  +  
Sbjct: 61  LWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALK 120

Query: 101 LGPYCFYSFSGIAGTNYLGYAVTFP--------YPYAKFPLACVDPPHYEEYHLTLQALD 152
            GP+C +  S    T    Y   F         Y  + +   C++P     +H++L +  
Sbjct: 121 DGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSAL 180

Query: 153 LCLSFTLL 160
           LC+S   L
Sbjct: 181 LCISLLQL 188


>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
           [Homo sapiens]
          Length = 200

 Score = 31.6 bits (70), Expect = 0.44
 Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 15/114 (13%)

Query: 9   GRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLAYREW 68
           G I +  GI++   GVI  F +    P F  +      P W   L I +G  L+   R+ 
Sbjct: 51  GTIQILFGIMTFSFGVIFLFTLLKPYPRFP-FIFLSGYPFWGSVLFINSGAFLIAVKRKT 109

Query: 69  TQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYL-GYA 121
           T+        T +ILS +   ++F  AL  A+ G     +F  I   NY+ GY+
Sbjct: 110 TE--------TLIILSRI---MNFLSAL-GAIAG-IILLTFGFILDQNYICGYS 150


>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
          Length = 539

 Score = 30.4 bits (67), Expect = 0.99
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 10  RILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLAYREWT 69
           RI++ LG   +  G +     F+     T   VR +CP W G   + +G++ +++++   
Sbjct: 30  RIVLALGATQMALGCLIVAVSFAALALTTSARVRHSCPFWAGFSVLLSGLIGVVSWK--- 86

Query: 70  QRYLGEATFTFVILSIMGCPLHFA 93
            R L      F++LS +   L+ A
Sbjct: 87  -RPLSLVITFFMLLSAVCVMLNLA 109


>gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide 22
           [Homo sapiens]
          Length = 531

 Score = 29.3 bits (64), Expect = 2.2
 Identities = 16/42 (38%), Positives = 21/42 (50%)

Query: 144 YHLTLQALDLCLSFTLLCTSLTVFIKLSARLIQNGHINMQLP 185
           + L L+ L LC SF + C  L  F +   R    GH+ M LP
Sbjct: 36  FRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMYLP 77


>gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens]
          Length = 201

 Score = 29.3 bits (64), Expect = 2.2
 Identities = 35/166 (21%), Positives = 65/166 (39%), Gaps = 29/166 (17%)

Query: 11  ILVTLGILSVCSGVIAFFP------VFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLA 64
           +L+ L + S+   ++ +FP        S K     W     C      L +TT +L+L  
Sbjct: 13  LLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIVTTVLLVLEN 72

Query: 65  YREW--------TQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCF------YSFS 110
              +        +++Y+   +  F  L I        I+    + GPYC       Y+F 
Sbjct: 73  NNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYCRTLDGWEYAFE 132

Query: 111 GIAGTNYLGYAVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLS 156
           G AG      ++          + C++P H  E+++ L ++ + LS
Sbjct: 133 GTAGRFLTDSSIW---------IQCLEPAHVVEWNIILFSILITLS 169


>gi|157671931 solute carrier family 5 (sodium/glucose
           cotransporter), member 12 [Homo sapiens]
          Length = 618

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 2/77 (2%)

Query: 100 LLGPYCFYSFSGIAGTNYLGYAVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTL 159
           L G +   +FSG   T            +  F  +C   PH  +   T  +  LCL F +
Sbjct: 333 LPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCF--PHLSDKLSTWISKGLCLLFGV 390

Query: 160 LCTSLTVFIKLSARLIQ 176
           +CTS+ V   +   ++Q
Sbjct: 391 MCTSMAVAASVMGGVVQ 407


>gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo
           sapiens]
          Length = 352

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 11/79 (13%)

Query: 56  TTGVLLLLAYREWTQRYLGEATFTFVILSIM--GC----PLHFAIALESALLGPYC---- 105
           TT +L+L  +  W   Y+G +  +F++L I+  GC     +H  I++  AL   +C    
Sbjct: 240 TTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNP 299

Query: 106 -FYSFSGIAGTNYLGYAVT 123
             Y+F G        +A+T
Sbjct: 300 ILYAFLGAKFKTSAQHALT 318


>gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo
           sapiens]
          Length = 356

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 11/79 (13%)

Query: 56  TTGVLLLLAYREWTQRYLGEATFTFVILSIM--GC----PLHFAIALESALLGPYC---- 105
           TT +L+L  +  W   Y+G +  +F++L I+  GC     +H  I++  AL   +C    
Sbjct: 244 TTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNP 303

Query: 106 -FYSFSGIAGTNYLGYAVT 123
             Y+F G        +A+T
Sbjct: 304 ILYAFLGAKFKTSAQHALT 322


>gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]
          Length = 668

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 12  LVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLAYREWTQR 71
           L+TLG++ V  G++            T  S++ +CP W G     +GV+ +++   W + 
Sbjct: 34  LLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSLAFSGVVGIVS---WKRP 90

Query: 72  YLGEATFTFVILSIMGCPLHFA 93
           +    +F F +LS++   L  A
Sbjct: 91  FTLVISF-FSLLSVLCVMLSMA 111


>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
          Length = 360

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 11/25 (44%), Positives = 18/25 (72%)

Query: 9   GRILVTLGILSVCSGVIAFFPVFSY 33
           GR LVTLGI+ V S ++++ P+  +
Sbjct: 148 GRALVTLGIMWVLSALVSYLPLMGW 172


>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
           [Homo sapiens]
          Length = 173

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 5   YQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLA 64
           Y  A R  + L  L   SG+I     F+++P F+    RI+ P   G +  ++ + ++LA
Sbjct: 60  YWNATRAFMILSALCAISGIIMGIMAFAHQPTFS----RISRPFSAGIMFFSSTLFVVLA 115

Query: 65  YREWT 69
              +T
Sbjct: 116 LAIYT 120


>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
           [Homo sapiens]
          Length = 215

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 5   YQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLA 64
           Y  A R  + L  L   SG+I     F+++P F+    RI+ P   G +  ++ + ++LA
Sbjct: 102 YWNATRAFMILSALCAISGIIMGIMAFAHQPTFS----RISRPFSAGIMFFSSTLFVVLA 157

Query: 65  YREWT 69
              +T
Sbjct: 158 LAIYT 162


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.143    0.474 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,711,653
Number of Sequences: 37866
Number of extensions: 323537
Number of successful extensions: 757
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 751
Number of HSP's gapped (non-prelim): 15
length of query: 194
length of database: 18,247,518
effective HSP length: 97
effective length of query: 97
effective length of database: 14,574,516
effective search space: 1413728052
effective search space used: 1413728052
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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