Guide to the Human Genome
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Search of human proteins with 239749320

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749320 PREDICTED: hypothetical protein XP_002346995 [Homo
sapiens]
         (103 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754793 PREDICTED: similar to Small ubiquitin-related modif...   209   3e-55
gi|239749320 PREDICTED: hypothetical protein XP_002346995 [Homo ...   209   3e-55
gi|239509111 PREDICTED: similar to Small ubiquitin-related modif...   209   3e-55
gi|239743410 PREDICTED: hypothetical protein XP_002342830 [Homo ...   206   3e-54
gi|54792071 SMT3 suppressor of mif two 3 homolog 2 isoform b pre...   118   1e-27
gi|54792069 SMT3 suppressor of mif two 3 homolog 2 isoform a pre...   106   3e-24
gi|169169820 PREDICTED: similar to SMT3 supressor of mif two 3 h...   105   6e-24
gi|239748082 PREDICTED: similar to SMT3 suppressor of mif two 3 ...   102   8e-23
gi|239741979 PREDICTED: hypothetical protein XP_002342366 [Homo ...   102   8e-23
gi|50400081 SMT3 suppressor of mif two 3 homolog 4 [Homo sapiens]      98   1e-21
gi|48928058 small ubiquitin-like modifier protein 3 [Homo sapiens]     98   1e-21
gi|239754164 PREDICTED: similar to mCG21560 [Homo sapiens]             84   2e-17
gi|239748701 PREDICTED: similar to mCG21560 [Homo sapiens]             84   2e-17
gi|239742728 PREDICTED: similar to mCG21560 [Homo sapiens]             84   2e-17
gi|54792065 SMT3 suppressor of mif two 3 homolog 1 isoform a pre...    50   4e-07
gi|4507801 SMT3 suppressor of mif two 3 homolog 1 isoform a prec...    50   4e-07
gi|54792067 SMT3 suppressor of mif two 3 homolog 1 isoform b pre...    38   0.001
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    29   0.91 
gi|11038659 ADAM metallopeptidase with thrombospondin type 1 mot...    28   2.0  
gi|110825974 ADAM metallopeptidase with thrombospondin type 1 mo...    28   2.0  
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]         27   4.5  
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform...    26   7.7  

>gi|239754793 PREDICTED: similar to Small ubiquitin-related modifier
           2 [Homo sapiens]
          Length = 103

 Score =  209 bits (533), Expect = 3e-55
 Identities = 103/103 (100%), Positives = 103/103 (100%)

Query: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
           MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI
Sbjct: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60

Query: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS 103
           DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS
Sbjct: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS 103


>gi|239749320 PREDICTED: hypothetical protein XP_002346995 [Homo
           sapiens]
          Length = 103

 Score =  209 bits (533), Expect = 3e-55
 Identities = 103/103 (100%), Positives = 103/103 (100%)

Query: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
           MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI
Sbjct: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60

Query: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS 103
           DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS
Sbjct: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS 103


>gi|239509111 PREDICTED: similar to Small ubiquitin-related modifier
           2 [Homo sapiens]
          Length = 103

 Score =  209 bits (533), Expect = 3e-55
 Identities = 103/103 (100%), Positives = 103/103 (100%)

Query: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
           MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI
Sbjct: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60

Query: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS 103
           DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS
Sbjct: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS 103


>gi|239743410 PREDICTED: hypothetical protein XP_002342830 [Homo
           sapiens]
          Length = 103

 Score =  206 bits (524), Expect = 3e-54
 Identities = 101/103 (98%), Positives = 102/103 (99%)

Query: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
           MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI
Sbjct: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60

Query: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTRMTFSVRNLQFGSTTS 103
           DVFQQQTGVSTEKAAYFFPPELCSLQT+MTFSVR LQFGSTTS
Sbjct: 61  DVFQQQTGVSTEKAAYFFPPELCSLQTKMTFSVRKLQFGSTTS 103


>gi|54792071 SMT3 suppressor of mif two 3 homolog 2 isoform b
          precursor [Homo sapiens]
          Length = 71

 Score =  118 bits (295), Expect = 1e-27
 Identities = 57/68 (83%), Positives = 60/68 (88%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
          MA++   EGVKTENNDHINLKV GQD SVVQFKIKRHTPLSKLM AYC+ QLEMEDE TI
Sbjct: 1  MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQLEMEDEDTI 60

Query: 61 DVFQQQTG 68
          DVFQQQTG
Sbjct: 61 DVFQQQTG 68


>gi|54792069 SMT3 suppressor of mif two 3 homolog 2 isoform a
          precursor [Homo sapiens]
          Length = 95

 Score =  106 bits (265), Expect = 3e-24
 Identities = 58/92 (63%), Positives = 61/92 (66%), Gaps = 24/92 (26%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCD----------- 49
          MA++   EGVKTENNDHINLKV GQD SVVQFKIKRHTPLSKLM AYC+           
Sbjct: 1  MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF 60

Query: 50 -------------AQLEMEDEGTIDVFQQQTG 68
                       AQLEMEDE TIDVFQQQTG
Sbjct: 61 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTG 92


>gi|169169820 PREDICTED: similar to SMT3 supressor of mif two 3
          homolog 2 [Homo sapiens]
          Length = 70

 Score =  105 bits (263), Expect = 6e-24
 Identities = 54/68 (79%), Positives = 58/68 (85%), Gaps = 1/68 (1%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
          MA+K   EGVKT+NN HINLKVVGQ  SVVQFKIKRHTPLSKLM AYC+ QLEME+E TI
Sbjct: 1  MADKKPQEGVKTKNN-HINLKVVGQGGSVVQFKIKRHTPLSKLMKAYCELQLEMENEDTI 59

Query: 61 DVFQQQTG 68
          DVFQQQ G
Sbjct: 60 DVFQQQMG 67


>gi|239748082 PREDICTED: similar to SMT3 suppressor of mif two 3
           homolog 2 [Homo sapiens]
          Length = 206

 Score =  102 bits (253), Expect = 8e-23
 Identities = 48/68 (70%), Positives = 57/68 (83%)

Query: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
           +A++   EG++TEN DHINLKV GQ+ SVVQF+IKRHTPLSKLM AY  AQLEMEDE T 
Sbjct: 136 VADEKPKEGIETENKDHINLKVAGQEGSVVQFRIKRHTPLSKLMKAYTPAQLEMEDEDTT 195

Query: 61  DVFQQQTG 68
           D+FQQQ+G
Sbjct: 196 DMFQQQSG 203


>gi|239741979 PREDICTED: hypothetical protein XP_002342366 [Homo
           sapiens]
          Length = 164

 Score =  102 bits (253), Expect = 8e-23
 Identities = 48/68 (70%), Positives = 57/68 (83%)

Query: 1   MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTI 60
           +A++   EG++TEN DHINLKV GQ+ SVVQF+IKRHTPLSKLM AY  AQLEMEDE T 
Sbjct: 94  VADEKPKEGIETENKDHINLKVAGQEGSVVQFRIKRHTPLSKLMKAYTPAQLEMEDEDTT 153

Query: 61  DVFQQQTG 68
           D+FQQQ+G
Sbjct: 154 DMFQQQSG 161


>gi|50400081 SMT3 suppressor of mif two 3 homolog 4 [Homo sapiens]
          Length = 95

 Score = 98.2 bits (243), Expect = 1e-21
 Identities = 55/92 (59%), Positives = 58/92 (63%), Gaps = 24/92 (26%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCD----------- 49
          MAN+   E VKTENN+HINLKV GQD SVVQFKIKR TPLSKLM AYC+           
Sbjct: 1  MANEKPTEEVKTENNNHINLKVAGQDGSVVQFKIKRQTPLSKLMKAYCEPRGLSVKQIRF 60

Query: 50 -------------AQLEMEDEGTIDVFQQQTG 68
                       AQLEMEDE TIDVFQQ TG
Sbjct: 61 RFGGQPISGTDKPAQLEMEDEDTIDVFQQPTG 92


>gi|48928058 small ubiquitin-like modifier protein 3 [Homo
          sapiens]
          Length = 103

 Score = 98.2 bits (243), Expect = 1e-21
 Identities = 56/92 (60%), Positives = 59/92 (64%), Gaps = 25/92 (27%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCD----------- 49
          M+ +   EGVKTEN DHINLKV GQD SVVQFKIKRHTPLSKLM AYC+           
Sbjct: 1  MSEEKPKEGVKTEN-DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF 59

Query: 50 -------------AQLEMEDEGTIDVFQQQTG 68
                       AQLEMEDE TIDVFQQQTG
Sbjct: 60 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTG 91


>gi|239754164 PREDICTED: similar to mCG21560 [Homo sapiens]
          Length = 93

 Score = 84.3 bits (207), Expect = 2e-17
 Identities = 39/49 (79%), Positives = 42/49 (85%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCD 49
          MA++   EGVKTENNDHINLKV GQD SV QFKIKRHTPLSKLM AYC+
Sbjct: 45 MADEKPKEGVKTENNDHINLKVAGQDGSVAQFKIKRHTPLSKLMKAYCE 93


>gi|239748701 PREDICTED: similar to mCG21560 [Homo sapiens]
          Length = 93

 Score = 84.3 bits (207), Expect = 2e-17
 Identities = 39/49 (79%), Positives = 42/49 (85%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCD 49
          MA++   EGVKTENNDHINLKV GQD SV QFKIKRHTPLSKLM AYC+
Sbjct: 45 MADEKPKEGVKTENNDHINLKVAGQDGSVAQFKIKRHTPLSKLMKAYCE 93


>gi|239742728 PREDICTED: similar to mCG21560 [Homo sapiens]
          Length = 93

 Score = 84.3 bits (207), Expect = 2e-17
 Identities = 39/49 (79%), Positives = 42/49 (85%)

Query: 1  MANKNSNEGVKTENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCD 49
          MA++   EGVKTENNDHINLKV GQD SV QFKIKRHTPLSKLM AYC+
Sbjct: 45 MADEKPKEGVKTENNDHINLKVAGQDGSVAQFKIKRHTPLSKLMKAYCE 93


>gi|54792065 SMT3 suppressor of mif two 3 homolog 1 isoform a
          precursor [Homo sapiens]
          Length = 101

 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 24/80 (30%)

Query: 13 ENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQ--------------------- 51
          +  ++I LKV+GQD S + FK+K  T L KL  +YC  Q                     
Sbjct: 17 KEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHT 76

Query: 52 ---LEMEDEGTIDVFQQQTG 68
             L ME+E  I+V+Q+QTG
Sbjct: 77 PKELGMEEEDVIEVYQEQTG 96


>gi|4507801 SMT3 suppressor of mif two 3 homolog 1 isoform a
          precursor [Homo sapiens]
          Length = 101

 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 24/80 (30%)

Query: 13 ENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQ--------------------- 51
          +  ++I LKV+GQD S + FK+K  T L KL  +YC  Q                     
Sbjct: 17 KEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHT 76

Query: 52 ---LEMEDEGTIDVFQQQTG 68
             L ME+E  I+V+Q+QTG
Sbjct: 77 PKELGMEEEDVIEVYQEQTG 96


>gi|54792067 SMT3 suppressor of mif two 3 homolog 1 isoform b
          precursor [Homo sapiens]
          Length = 76

 Score = 38.1 bits (87), Expect = 0.001
 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 24/68 (35%)

Query: 25 QDDSVVQFKIKRHTPLSKLMNAYCDAQ------------------------LEMEDEGTI 60
          QD S + FK+K  T L KL  +YC  Q                        L ME+E  I
Sbjct: 4  QDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVI 63

Query: 61 DVFQQQTG 68
          +V+Q+QTG
Sbjct: 64 EVYQEQTG 71


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 16/68 (23%), Positives = 29/68 (42%)

Query: 13  ENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEGTIDVFQQQTGVSTE 72
           E  DH +    G D      ++KR   ++    A  D ++  ++ GT+D+F     +S+ 
Sbjct: 265 EEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSG 324

Query: 73  KAAYFFPP 80
                 PP
Sbjct: 325 SDGEDKPP 332


>gi|11038659 ADAM metallopeptidase with thrombospondin type 1 motif,
           2 isoform 2 [Homo sapiens]
          Length = 566

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 2   ANKNSNEGVKTENNDHINLKVV-GQDDSVVQFKIKRHTP--LSKLMN 45
           AN +     +   +D  N++V+ G DDSVVQF  K H    L  LMN
Sbjct: 250 ANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMN 296


>gi|110825974 ADAM metallopeptidase with thrombospondin type 1
           motif, 2 isoform 1 preproprotein [Homo sapiens]
          Length = 1211

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 2   ANKNSNEGVKTENNDHINLKVV-GQDDSVVQFKIKRHTP--LSKLMN 45
           AN +     +   +D  N++V+ G DDSVVQF  K H    L  LMN
Sbjct: 250 ANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMN 296


>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
          Length = 3639

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 9/35 (25%), Positives = 20/35 (57%)

Query: 24  GQDDSVVQFKIKRHTPLSKLMNAYCDAQLEMEDEG 58
           GQD +  +  ++RH  L +++ A+      +E++G
Sbjct: 739 GQDQAAAETLLRRHVRLERVLRAFAAELRRLEEQG 773


>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
           [Homo sapiens]
          Length = 1045

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 22/99 (22%), Positives = 40/99 (40%), Gaps = 20/99 (20%)

Query: 12  TENNDHINLKVVGQDDSVVQFKIKRHTPLSKLMNAYCD---------AQLEMEDEGTIDV 62
           T +   +++K+   DD+   F++ +  P   L++A C+           LE  D   I V
Sbjct: 34  TPSGKLVSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITV 93

Query: 63  F-----------QQQTGVSTEKAAYFFPPELCSLQTRMT 90
           +           ++   V  +    FFPP+   LQ  +T
Sbjct: 94  WLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELT 132


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,535,094
Number of Sequences: 37866
Number of extensions: 117303
Number of successful extensions: 186
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 159
Number of HSP's gapped (non-prelim): 22
length of query: 103
length of database: 18,247,518
effective HSP length: 74
effective length of query: 29
effective length of database: 15,445,434
effective search space: 447917586
effective search space used: 447917586
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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