Search of human proteins with 116812626

Search of human proteins with 116812626

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116812626 fatty acid desaturase domain family, member 6
[Homo sapiens]
         (350 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116812626 fatty acid desaturase domain family, member 6 [Homo...   720   0.0  
gi|214831730 fatty acid desaturase 1 [Homo sapiens]                    45   1e-04
gi|13375616 fatty acid desaturase 3 [Homo sapiens]                     38   0.012
gi|4758334 fatty acid desaturase 2 [Homo sapiens]                      35   0.077
gi|14210538 5'-nucleotidase, cytosolic IA [Homo sapiens]               30   2.5  
gi|40255251 hypothetical protein LOC131408 [Homo sapiens]              30   2.5  
gi|59853162 thymine-DNA glycosylase [Homo sapiens]                     30   4.2  
gi|38788319 guanine nucleotide binding protein-like 1 [Homo sapi...    28   9.4  

>gi|116812626 fatty acid desaturase domain family, member 6 [Homo
           sapiens]
          Length = 350

 Score =  720 bits (1858), Expect = 0.0
 Identities = 350/350 (100%), Positives = 350/350 (100%)

Query: 1   MEPTEPMEPTEPMEPARSAHRGGEALLRELEVLVQDVVRTSSWWERHGVDCAILALSLFA 60
           MEPTEPMEPTEPMEPARSAHRGGEALLRELEVLVQDVVRTSSWWERHGVDCAILALSLFA
Sbjct: 1   MEPTEPMEPTEPMEPARSAHRGGEALLRELEVLVQDVVRTSSWWERHGVDCAILALSLFA 60

Query: 61  LPAGFLCLRWENALVFASGITILGVCHYTLTVKGSHLATHGALTESKRWSKIWLLFFVEV 120
           LPAGFLCLRWENALVFASGITILGVCHYTLTVKGSHLATHGALTESKRWSKIWLLFFVEV
Sbjct: 61  LPAGFLCLRWENALVFASGITILGVCHYTLTVKGSHLATHGALTESKRWSKIWLLFFVEV 120

Query: 121 CTAFTAEHATHGHVKMHHAYTNVVGLGDSSTWRLPCLNRYVYMFLAPFLLPIATPLVAVE 180
           CTAFTAEHATHGHVKMHHAYTNVVGLGDSSTWRLPCLNRYVYMFLAPFLLPIATPLVAVE
Sbjct: 121 CTAFTAEHATHGHVKMHHAYTNVVGLGDSSTWRLPCLNRYVYMFLAPFLLPIATPLVAVE 180

Query: 181 RLRKVELGTALRTLALISLGLYSHYWLLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNI 240
           RLRKVELGTALRTLALISLGLYSHYWLLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNI
Sbjct: 181 RLRKVELGTALRTLALISLGLYSHYWLLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNI 240

Query: 241 FQHIGLPMFSRDNKPRRIHMMSLGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMC 300
           FQHIGLPMFSRDNKPRRIHMMSLGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMC
Sbjct: 241 FQHIGLPMFSRDNKPRRIHMMSLGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMC 300

Query: 301 LKVKPVVSQFLREKQLPYNEDSYLARFQLFLRRYEEFMVQAPPITELVGL 350
           LKVKPVVSQFLREKQLPYNEDSYLARFQLFLRRYEEFMVQAPPITELVGL
Sbjct: 301 LKVKPVVSQFLREKQLPYNEDSYLARFQLFLRRYEEFMVQAPPITELVGL 350


>gi|214831730 fatty acid desaturase 1 [Homo sapiens]
          Length = 501

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 46/199 (23%), Positives = 80/199 (40%), Gaps = 19/199 (9%)

Query: 144 VGLGDSSTWRLPCLNRYVYMFLA--PFLLPIATP----LVAVERLRKVELGTALRTLALI 197
           V LG      +P  +++ Y FL   P LLP+          ++R + V+L   +      
Sbjct: 304 VELGKQKKKYMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVIQRKKWVDLAWMIT----F 359

Query: 198 SLGLYSHYWLLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNIFQHIGLPMFSRDNKPRR 257
            +  +  Y  LL +  F      LG  F+ R L ++ ++ V    HI + +   D     
Sbjct: 360 YVRFFLTYVPLLGLKAF------LGLFFIVRFLESNWFVWVTQMNHIPMHI-DHDRNMDW 412

Query: 258 IHMMSLGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMCLKVKPVVSQFLREKQLP 317
           +        N+ +    DW  GH  ++  +EHHLFP +  +   KV P+V     +  + 
Sbjct: 413 VSTQLQATCNVHKSAFNDWFSGH--LNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIE 470

Query: 318 YNEDSYLARFQLFLRRYEE 336
           Y     L+ F   +   +E
Sbjct: 471 YQSKPLLSAFADIIHSLKE 489


>gi|13375616 fatty acid desaturase 3 [Homo sapiens]
          Length = 445

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 54/251 (21%), Positives = 90/251 (35%), Gaps = 33/251 (13%)

Query: 96  HLATHGALTESKRWSKIWLLFFVEVCTAFTAEHATHGHVKMHHAYTNVVG---------- 145
           H   H ++ +   W+ +   F +     F+A      H + HHA  N+            
Sbjct: 182 HDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQ-HHAKPNIFHKDPDVTVAPV 240

Query: 146 --LGDSSTWR-------LPCLNRYVYMFLAPFLLPIATPLVAVERLRKVELGTALRTLAL 196
             LG+SS          LP   +++Y FL      I  PL+ +       L   L  +  
Sbjct: 241 FLLGESSVEYGKKKRRYLPYNQQHLYFFL------IGPPLLTLVNFEVENLAYMLVCMQW 294

Query: 197 ISLGLYSHYW--LLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNIFQHIGLPMFSRDNK 254
             L   + ++    L+   F      L      R L +H ++ +    HI  P      K
Sbjct: 295 ADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHI--PKEIGHEK 352

Query: 255 PRR-IHMMSLGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMCLKVKPVVSQFLRE 313
            R  +        N+      +W  GH  ++  +EHHLFPR+  +   +V P+V     +
Sbjct: 353 HRDWVSSQLAATCNVEPSLFTNWFSGH--LNFQIEHHLFPRMPRHNYSRVAPLVKSLCAK 410

Query: 314 KQLPYNEDSYL 324
             L Y    +L
Sbjct: 411 HGLSYEVKPFL 421


>gi|4758334 fatty acid desaturase 2 [Homo sapiens]
          Length = 444

 Score = 35.4 bits (80), Expect = 0.077
 Identities = 52/253 (20%), Positives = 91/253 (35%), Gaps = 44/253 (17%)

Query: 100 HGALTESKRWSKIWLLFFVEVCTAFTAEHATHGHVKMHHAYTNV---------------- 143
           H ++    +W+ +   F +      +A    H H + HHA  N+                
Sbjct: 184 HLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ-HHAKPNIFHKDPDVNMLHVFVLG 242

Query: 144 ----VGLGDSSTWRLPCLNRYVYMFLA--PFLLPIATP----LVAVERLRKVELGTALRT 193
               +  G      LP  +++ Y FL   P L+P+       +  +     V+L  A+  
Sbjct: 243 EWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSY 302

Query: 194 LALISLGLYSHYWLLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNIFQHIGLPMFSRDN 253
                +     Y +L           AL  +   R L +H ++ V    HI + +   D 
Sbjct: 303 YIRFFITYIPFYGIL----------GALLFLNFIRFLESHWFVWVTQMNHIVMEI---DQ 349

Query: 254 KPRRIHMMS--LGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMCLKVKPVVSQFL 311
           +  R    S      N+ +    DW  GH  ++  +EHHLFP +  +   K+ P+V    
Sbjct: 350 EAYRDWFSSQLTATCNVEQSFFNDWFSGH--LNFQIEHHLFPTMPRHNLHKIAPLVKSLC 407

Query: 312 REKQLPYNEDSYL 324
            +  + Y E   L
Sbjct: 408 AKHGIEYQEKPLL 420


>gi|14210538 5'-nucleotidase, cytosolic IA [Homo sapiens]
          Length = 368

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 1  MEPTEPMEPTEPMEPARSAHRGGEALLRELEVLVQDVV---RTSSWWERHGVDCAILALS 57
          MEP +P EP EP EP   A      +  E ++   ++    +  S   ++ V  A+ + +
Sbjct: 1  MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRA 60

Query: 58 LFAL 61
          LF +
Sbjct: 61 LFRM 64


>gi|40255251 hypothetical protein LOC131408 [Homo sapiens]
          Length = 335

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 163 MFLAP--FLLPIATPLVAVERLRKVELGTALRTLALISLGLYSHYWLLLNVSGFKNPSSA 220
           MFLA   FLLP A P   V    +  LG+ L +LA ++L  +SH  + ++   + +PS++
Sbjct: 1   MFLATLSFLLPFAHPFGTVSC--EYMLGSPLSSLAQVNLSPFSHPKVHMD-PNYCHPSTS 57

Query: 221 LGCMFLTRSL--LAHPYLHVNIFQ 242
           L    L  S   L HP L   I Q
Sbjct: 58  LHLCSLAWSFTRLLHPPLSPGISQ 81


>gi|59853162 thymine-DNA glycosylase [Homo sapiens]
          Length = 410

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 37/143 (25%), Positives = 56/143 (39%), Gaps = 19/143 (13%)

Query: 4   TEPMEPTEPMEPARSAHRGGEALLRELEVLVQDVVRTSSWWER-HGVDCAILALSLFALP 62
           TEP +P EP +P  S   G  A  +E +  + D  +     +R +GV  A L      LP
Sbjct: 68  TEPKQPVEPKKPVESKKSGKSAKSKEKQEKITDTFKVKRKVDRFNGVSEAELLTK--TLP 125

Query: 63  AGFLCLRWENALVFASGITILGVCHYTLTV-KGSHLATHGALTESKRWSKIWLLFFVEVC 121
                    + L F   I I+G+    +   KG H    G    +  W  +++    EV 
Sbjct: 126 ---------DILTFNLDIVIIGINPGLMAAYKGHHYPGPG----NHFWKCLFMSGLSEVQ 172

Query: 122 TAFTAEHATHGHVKMHHAYTNVV 144
                +H   G  K    +TN+V
Sbjct: 173 LNHMDDHTLPG--KYGIGFTNMV 193


>gi|38788319 guanine nucleotide binding protein-like 1 [Homo
           sapiens]
          Length = 607

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 6/57 (10%)

Query: 2   EPTEPMEPTEPMEPARSAHRGG------EALLRELEVLVQDVVRTSSWWERHGVDCA 52
           +P  P +P+  ++ +R   RG       E LLR  E +    V  SSW E+   D A
Sbjct: 260 DPRTPQDPSSVLKKSRRRGRGWTRALGPEQLLRACEAITVGKVDLSSWREKIARDVA 316


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,715,840
Number of Sequences: 37866
Number of extensions: 577188
Number of successful extensions: 1473
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1460
Number of HSP's gapped (non-prelim): 10
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.