Search of human proteins with 23199983

Search of human proteins with 23199983

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23199983 phosphatidylinositol glycan anchor biosynthesis,
class K precursor [Homo sapiens]
         (395 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23199983 phosphatidylinositol glycan anchor biosynthesis, cla...   801   0.0  
gi|56682964 legumain preproprotein [Homo sapiens]                     108   8e-24
gi|56682962 legumain preproprotein [Homo sapiens]                     108   8e-24
gi|148792970 TAF4b RNA polymerase II, TATA box binding protein (...    30   3.8  
gi|6912286 caspase 14 precursor [Homo sapiens]                         30   5.0  
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     29   6.5  
gi|34485722 karyopherin alpha 3 [Homo sapiens]                         29   8.5  

>gi|23199983 phosphatidylinositol glycan anchor biosynthesis, class
           K precursor [Homo sapiens]
          Length = 395

 Score =  801 bits (2070), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYR 60
           MAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYR
Sbjct: 1   MAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYR 60

Query: 61  HVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVD 120
           HVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVD
Sbjct: 61  HVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVD 120

Query: 121 YRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITN 180
           YRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITN
Sbjct: 121 YRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITN 180

Query: 181 IELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPA 240
           IELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPA
Sbjct: 181 IELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPA 240

Query: 241 IGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLI 300
           IGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLI
Sbjct: 241 IGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLI 300

Query: 301 TDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPK 360
           TDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPK
Sbjct: 301 TDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPK 360

Query: 361 LKDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF 395
           LKDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF
Sbjct: 361 LKDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF 395


>gi|56682964 legumain preproprotein [Homo sapiens]
          Length = 433

 Score =  108 bits (270), Expect = 8e-24
 Identities = 69/214 (32%), Positives = 107/214 (50%), Gaps = 6/214 (2%)

Query: 45  NWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFS 104
           +W V+V  S  W+NYRH A+    Y+ + R GIPD  IV+M+ DD+A +  NP P  V +
Sbjct: 29  HWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVIN 88

Query: 105 HKNMELNVYGDDVEVDYRSYEVTVENFLRVLTG--RIPPSTPRSKRLLSDDRSNILIYMT 162
             N   +VY   V  DY   +VT +NFL VL G           K L S  + ++ IY T
Sbjct: 89  RPN-GTDVY-QGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146

Query: 163 GHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERF-YSPNIM 221
            HG  G L F  +E++   +L +    M++ + Y +++F I+ C+  SM      + N+ 
Sbjct: 147 DHGSTGILVF-PNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205

Query: 222 ALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLE 255
           A  ++   E S +   D     +L D Y+   +E
Sbjct: 206 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWME 239


>gi|56682962 legumain preproprotein [Homo sapiens]
          Length = 433

 Score =  108 bits (270), Expect = 8e-24
 Identities = 69/214 (32%), Positives = 107/214 (50%), Gaps = 6/214 (2%)

Query: 45  NWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFS 104
           +W V+V  S  W+NYRH A+    Y+ + R GIPD  IV+M+ DD+A +  NP P  V +
Sbjct: 29  HWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVIN 88

Query: 105 HKNMELNVYGDDVEVDYRSYEVTVENFLRVLTG--RIPPSTPRSKRLLSDDRSNILIYMT 162
             N   +VY   V  DY   +VT +NFL VL G           K L S  + ++ IY T
Sbjct: 89  RPN-GTDVY-QGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146

Query: 163 GHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERF-YSPNIM 221
            HG  G L F  +E++   +L +    M++ + Y +++F I+ C+  SM      + N+ 
Sbjct: 147 DHGSTGILVF-PNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205

Query: 222 ALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLE 255
           A  ++   E S +   D     +L D Y+   +E
Sbjct: 206 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWME 239


>gi|148792970 TAF4b RNA polymerase II, TATA box binding protein
           (TBP)-associated factor, 105kDa [Homo sapiens]
          Length = 862

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 10/112 (8%)

Query: 258 EEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETI 317
           + +N  SQ     L  +  K   ++   HR   ++     +L +D    ++ +E   +  
Sbjct: 679 DAVNLISQATQERLRGLLEKLTAIAQ--HRMTTYKASENYILCSDTRSQLKFLEKLDQLE 736

Query: 318 KLQQDSEIMES--------SYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPKL 361
           K ++D E  E         S KED    +L +  K  +QL +AQI H+   L
Sbjct: 737 KQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQHRDANL 788


>gi|6912286 caspase 14 precursor [Homo sapiens]
          Length = 242

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 1/58 (1%)

Query: 152 DDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAF-EQMWQKRRYNELLFIIDTCQG 208
           D  S   + +  HG  GFLK +D E +    L +A   +  Q  R    ++II  C+G
Sbjct: 77  DPVSCAFVVLMAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRG 134


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 25/117 (21%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 253 VLEFLEEINPASQTNMNDLFQVCPKSL-CVSTPGHRTDLFQRDPKNVLITDFFGSVRKVE 311
           +++ LE+ N   +  +  L QV    L   +    +T     + +N+++    G  +++E
Sbjct: 866 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIE 925

Query: 312 ITTETIKLQQDS-----EIMESSYK-EDQMDEKLMEPLKYAEQLPVAQIIHQKPKLK 362
           I T+ +  ++DS     E  E+ +K +++  EK+ +  K  ++    +++ Q+ KLK
Sbjct: 926 ILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLK 982


>gi|34485722 karyopherin alpha 3 [Homo sapiens]
          Length = 521

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 18/105 (17%)

Query: 95  RNPKPATVFSHKNM--ELNVYGDDVEVDYRSYEVTVENFLRVLTGRIP----PSTPRSKR 148
           +N +   +   +N+  E ++   DV+ D+++  VT+E  L+  T   P     +   +++
Sbjct: 38  KNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARK 97

Query: 149 LLSDDRS------------NILIYMTGHGGNGFLKFQDSEEITNI 181
           LLS DR+             IL+       N  L+F+ +  +TNI
Sbjct: 98  LLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNI 142


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,950,464
Number of Sequences: 37866
Number of extensions: 628467
Number of successful extensions: 1416
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1409
Number of HSP's gapped (non-prelim): 7
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.