Search of human proteins with 228480280

Search of human proteins with 228480280

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|228480280 Sep (O-phosphoserine) tRNA:Sec (selenocysteine)
tRNA synthase isoform 1 [Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|228480280 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRN...   997   0.0  
gi|228480284 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRN...   923   0.0  
gi|228480282 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRN...   816   0.0  
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s...    35   0.16 
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa...    35   0.16 
gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo...    31   2.3  
gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo...    31   2.3  

>gi|228480280 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA
           synthase isoform 1 [Homo sapiens]
          Length = 501

 Score =  997 bits (2578), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MNRESFAAGERLVSPAYVRQGCEARRSHEHLIRLLLEKGKCPENGWDESTLELFLHELAI 60
           MNRESFAAGERLVSPAYVRQGCEARRSHEHLIRLLLEKGKCPENGWDESTLELFLHELAI
Sbjct: 1   MNRESFAAGERLVSPAYVRQGCEARRSHEHLIRLLLEKGKCPENGWDESTLELFLHELAI 60

Query: 61  MDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSGDISAVQPKAAGSSLLNKITNS 120
           MDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSGDISAVQPKAAGSSLLNKITNS
Sbjct: 61  MDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSGDISAVQPKAAGSSLLNKITNS 120

Query: 121 LVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTLRHKRPKAKYIIWPRIDQKSCFKSMI 180
           LVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTLRHKRPKAKYIIWPRIDQKSCFKSMI
Sbjct: 121 LVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTLRHKRPKAKYIIWPRIDQKSCFKSMI 180

Query: 181 TAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCILCIHSTTSCFAPRVPDRLEELAV 240
           TAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCILCIHSTTSCFAPRVPDRLEELAV
Sbjct: 181 TAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCILCIHSTTSCFAPRVPDRLEELAV 240

Query: 241 ICANYDIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFND 300
           ICANYDIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFND
Sbjct: 241 ICANYDIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFND 300

Query: 301 SFIQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYN 360
           SFIQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYN
Sbjct: 301 SFIQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYN 360

Query: 361 ERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTRQVSGARVVPLGSMQTVSGYTFR 420
           ERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTRQVSGARVVPLGSMQTVSGYTFR
Sbjct: 361 ERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTRQVSGARVVPLGSMQTVSGYTFR 420

Query: 421 GFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCLKAVRKERSKESDDNYDKTEDVD 480
           GFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCLKAVRKERSKESDDNYDKTEDVD
Sbjct: 421 GFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCLKAVRKERSKESDDNYDKTEDVD 480

Query: 481 IEEMALKLDNVLLDTYQDASS 501
           IEEMALKLDNVLLDTYQDASS
Sbjct: 481 IEEMALKLDNVLLDTYQDASS 501


>gi|228480284 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA
           synthase isoform 3 [Homo sapiens]
          Length = 500

 Score =  923 bits (2385), Expect = 0.0
 Identities = 463/463 (100%), Positives = 463/463 (100%)

Query: 39  GKCPENGWDESTLELFLHELAIMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRS 98
           GKCPENGWDESTLELFLHELAIMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRS
Sbjct: 38  GKCPENGWDESTLELFLHELAIMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRS 97

Query: 99  GDISAVQPKAAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTLRHK 158
           GDISAVQPKAAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTLRHK
Sbjct: 98  GDISAVQPKAAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTLRHK 157

Query: 159 RPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCIL 218
           RPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCIL
Sbjct: 158 RPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCIL 217

Query: 219 CIHSTTSCFAPRVPDRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAF 278
           CIHSTTSCFAPRVPDRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAF
Sbjct: 218 CIHSTTSCFAPRVPDRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAF 277

Query: 279 VQSLDKNFMVPVGGAIIAGFNDSFIQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLL 338
           VQSLDKNFMVPVGGAIIAGFNDSFIQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLL
Sbjct: 278 VQSLDKNFMVPVGGAIIAGFNDSFIQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLL 337

Query: 339 KERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTR 398
           KERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTR
Sbjct: 338 KERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTR 397

Query: 399 QVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCL 458
           QVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCL
Sbjct: 398 QVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCL 457

Query: 459 KAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTYQDASS 501
           KAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTYQDASS
Sbjct: 458 KAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTYQDASS 500


>gi|228480282 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA
           synthase isoform 2 [Homo sapiens]
          Length = 422

 Score =  816 bits (2109), Expect = 0.0
 Identities = 412/412 (100%), Positives = 412/412 (100%)

Query: 90  RFIHGIGRSGDISAVQPKAAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLT 149
           RFIHGIGRSGDISAVQPKAAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLT
Sbjct: 11  RFIHGIGRSGDISAVQPKAAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLT 70

Query: 150 LCFLTLRHKRPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKV 209
           LCFLTLRHKRPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKV
Sbjct: 71  LCFLTLRHKRPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKV 130

Query: 210 QELGPDCILCIHSTTSCFAPRVPDRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQG 269
           QELGPDCILCIHSTTSCFAPRVPDRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQG
Sbjct: 131 QELGPDCILCIHSTTSCFAPRVPDRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQG 190

Query: 270 ARVGRIDAFVQSLDKNFMVPVGGAIIAGFNDSFIQEISKMYPGRASASPSLDVLITLLSL 329
           ARVGRIDAFVQSLDKNFMVPVGGAIIAGFNDSFIQEISKMYPGRASASPSLDVLITLLSL
Sbjct: 191 ARVGRIDAFVQSLDKNFMVPVGGAIIAGFNDSFIQEISKMYPGRASASPSLDVLITLLSL 250

Query: 330 GSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVT 389
           GSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVT
Sbjct: 251 GSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVT 310

Query: 390 QLGSMLFTRQVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDL 449
           QLGSMLFTRQVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDL
Sbjct: 311 QLGSMLFTRQVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDL 370

Query: 450 FIKRLDRCLKAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTYQDASS 501
           FIKRLDRCLKAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTYQDASS
Sbjct: 371 FIKRLDRCLKAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTYQDASS 422


>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
           sapiens]
          Length = 796

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 7/162 (4%)

Query: 336 KLLKERKEMFSYLS-NQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSM 394
           +LLKE+  + + L  +Q++ +     ERL  T     +L   ++T+ + +    T L   
Sbjct: 557 QLLKEKSSLGNELKESQLEIIQLKEKERLAKTEQE--TLLQIIETVKDEKLNLETTLQES 614

Query: 395 LFTRQVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRL 454
              RQ+    +  + + Q+ +   F   + +  +    Y N+ S IG + + +   +   
Sbjct: 615 TAARQIMEREIENIQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEMLSKMVMET 674

Query: 455 DRCLKAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTY 496
               + +++E  K S +N      +      L  D +LL+ Y
Sbjct: 675 KTDNQILKEELKKHSQENIKFENSIS----RLTEDKILLENY 712


>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
           sapiens]
          Length = 833

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 7/162 (4%)

Query: 336 KLLKERKEMFSYLS-NQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSM 394
           +LLKE+  + + L  +Q++ +     ERL  T     +L   ++T+ + +    T L   
Sbjct: 594 QLLKEKSSLGNELKESQLEIIQLKEKERLAKTEQE--TLLQIIETVKDEKLNLETTLQES 651

Query: 395 LFTRQVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRL 454
              RQ+    +  + + Q+ +   F   + +  +    Y N+ S IG + + +   +   
Sbjct: 652 TAARQIMEREIENIQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEMLSKMVMET 711

Query: 455 DRCLKAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTY 496
               + +++E  K S +N      +      L  D +LL+ Y
Sbjct: 712 KTDNQILKEELKKHSQENIKFENSIS----RLTEDKILLENY 749


>gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo
           sapiens]
          Length = 1321

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 36/162 (22%), Positives = 70/162 (43%), Gaps = 15/162 (9%)

Query: 246 DIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFNDSFIQE 305
           DIP ++N+       KC+ L+ +  +  + +A +++L+K   + +   I+         E
Sbjct: 830 DIPSMMNDV------KCLLLLAKVYKSHKKEAVIETLNK--ALDLQSRILKRVP----LE 877

Query: 306 ISKMYPGRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLL- 364
             +M P +   + S+ +      L    Y K ++  K++FSYL    K + E     LL 
Sbjct: 878 QPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQ 937

Query: 365 -HTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTRQVSGARV 405
            H        A+ L+T   H   +V  +  ++F +Q   A +
Sbjct: 938 GHLDLCEQHCAILLQTEQNHETASVL-MADLMFRKQKHEAAI 978


>gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo
           sapiens]
          Length = 1320

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 36/162 (22%), Positives = 70/162 (43%), Gaps = 15/162 (9%)

Query: 246 DIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFNDSFIQE 305
           DIP ++N+       KC+ L+ +  +  + +A +++L+K   + +   I+         E
Sbjct: 829 DIPSMMNDV------KCLLLLAKVYKSHKKEAVIETLNK--ALDLQSRILKRVP----LE 876

Query: 306 ISKMYPGRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLL- 364
             +M P +   + S+ +      L    Y K ++  K++FSYL    K + E     LL 
Sbjct: 877 QPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQ 936

Query: 365 -HTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTRQVSGARV 405
            H        A+ L+T   H   +V  +  ++F +Q   A +
Sbjct: 937 GHLDLCEQHCAILLQTEQNHETASVL-MADLMFRKQKHEAAI 977


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,104,327
Number of Sequences: 37866
Number of extensions: 700177
Number of successful extensions: 1853
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1850
Number of HSP's gapped (non-prelim): 7
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.