Guide to the Human Genome
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Search of human proteins with 227498224

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|227498224 beta-1,4-N-acetyl-galactosaminyl transferase 2
isoform b [Homo sapiens]
         (506 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|227498224 beta-1,4-N-acetyl-galactosaminyl transferase 2 isof...  1021   0.0  
gi|227497754 beta-1,4-N-acetyl-galactosaminyl transferase 2 isof...  1013   0.0  
gi|227497758 beta-1,4-N-acetyl-galactosaminyl transferase 2 isof...   972   0.0  
gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo ...   368   e-102
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                      31   3.0  
gi|46370057 ring finger protein 216 isoform b [Homo sapiens]           30   6.7  
gi|46358403 ring finger protein 216 isoform a [Homo sapiens]           30   6.7  
gi|222136639 methylenetetrahydrofolate dehydrogenase 1 [Homo sap...    29   8.8  
gi|82775371 coiled-coil domain containing 93 [Homo sapiens]            29   8.8  

>gi|227498224 beta-1,4-N-acetyl-galactosaminyl transferase 2 isoform
           b [Homo sapiens]
          Length = 506

 Score = 1021 bits (2639), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MTSGGSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEE 60
           MTSGGSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEE
Sbjct: 1   MTSGGSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEE 60

Query: 61  RLRNLFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREG 120
           RLRNLFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREG
Sbjct: 61  RLRNLFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREG 120

Query: 121 LPRPLPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLA 180
           LPRPLPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLA
Sbjct: 121 LPRPLPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLA 180

Query: 181 DVPDSVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPV 240
           DVPDSVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPV
Sbjct: 181 DVPDSVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPV 240

Query: 241 TIRHPVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQK 300
           TIRHPVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQK
Sbjct: 241 TIRHPVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQK 300

Query: 301 PLEIKDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEK 360
           PLEIKDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEK
Sbjct: 301 PLEIKDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEK 360

Query: 361 TELDVVGGSVLGNVFQFKLLLEQSENGACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHT 420
           TELDVVGGSVLGNVFQFKLLLEQSENGACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHT
Sbjct: 361 TELDVVGGSVLGNVFQFKLLLEQSENGACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHT 420

Query: 421 ERLQRVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNT 480
           ERLQRVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNT
Sbjct: 421 ERLQRVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNT 480

Query: 481 YRSNTLTRVQFKLALHYFKNHLQCAA 506
           YRSNTLTRVQFKLALHYFKNHLQCAA
Sbjct: 481 YRSNTLTRVQFKLALHYFKNHLQCAA 506


>gi|227497754 beta-1,4-N-acetyl-galactosaminyl transferase 2 isoform
           a [Homo sapiens]
          Length = 566

 Score = 1013 bits (2619), Expect = 0.0
 Identities = 502/502 (100%), Positives = 502/502 (100%)

Query: 5   GSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRN 64
           GSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRN
Sbjct: 65  GSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRN 124

Query: 65  LFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRP 124
           LFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRP
Sbjct: 125 LFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRP 184

Query: 125 LPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPD 184
           LPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPD
Sbjct: 185 LPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPD 244

Query: 185 SVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRH 244
           SVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRH
Sbjct: 245 SVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRH 304

Query: 245 PVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEI 304
           PVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEI
Sbjct: 305 PVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEI 364

Query: 305 KDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELD 364
           KDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELD
Sbjct: 365 KDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELD 424

Query: 365 VVGGSVLGNVFQFKLLLEQSENGACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQ 424
           VVGGSVLGNVFQFKLLLEQSENGACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQ
Sbjct: 425 VVGGSVLGNVFQFKLLLEQSENGACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQ 484

Query: 425 RVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSN 484
           RVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSN
Sbjct: 485 RVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSN 544

Query: 485 TLTRVQFKLALHYFKNHLQCAA 506
           TLTRVQFKLALHYFKNHLQCAA
Sbjct: 545 TLTRVQFKLALHYFKNHLQCAA 566


>gi|227497758 beta-1,4-N-acetyl-galactosaminyl transferase 2 isoform
           c [Homo sapiens]
          Length = 480

 Score =  972 bits (2512), Expect = 0.0
 Identities = 480/480 (100%), Positives = 480/480 (100%)

Query: 27  MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 86
           MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE
Sbjct: 1   MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 60

Query: 87  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 146
           QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP
Sbjct: 61  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 120

Query: 147 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 206
           LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK
Sbjct: 121 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 180

Query: 207 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 266
           FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA
Sbjct: 181 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 240

Query: 267 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 326
           TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL
Sbjct: 241 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 300

Query: 327 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 386
           AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN
Sbjct: 301 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 360

Query: 387 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 446
           GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG
Sbjct: 361 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 420

Query: 447 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 506
           TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA
Sbjct: 421 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 480


>gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo
           sapiens]
          Length = 533

 Score =  368 bits (945), Expect = e-102
 Identities = 223/529 (42%), Positives = 297/529 (56%), Gaps = 33/529 (6%)

Query: 9   LWL----LKILVIILVLGIVGFMFGSMFLQAVFSSP-KPELPSPAPGVQKLK-LLPEERL 62
           +WL    L  LV++L    +G ++ S         P  P  P  +P   +L  L PE R 
Sbjct: 1   MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAPEPRY 60

Query: 63  RNL---FSYDGIWLFPKNQCKCEAN---------KEQGGYNFQDAYGQSDLPAVKARRQA 110
            ++        + L   N C CE++         K+    +   A+  ++L A  A R+ 
Sbjct: 61  AHIPVRIKEQVVGLLAWNNCSCESSGGGLPLPFQKQVRAIDLTKAFDPAELRAASATREQ 120

Query: 111 EFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAP-VYEVTL 169
           EF+ F  R   P    L+   N P  YP+ GVEV PL ++ +PGL  +      VY+V L
Sbjct: 121 EFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQAASGQEVYQVNL 180

Query: 170 TASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSL 229
           TASLGT +   +V    + G GQ  L + +     L   LQ VTY+S  YQ    D V  
Sbjct: 181 TASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTVRF 240

Query: 230 ESRSSVAKFPVTIRHPVIPKLYDPGP-----ERKLRNLVTIATKTFLRPHKLMIMLRSIR 284
            +    A F + IRHP  P+LY PG      +  +  LVTIATKTFLR  +L  ++ SIR
Sbjct: 241 STEGHEAAFTIRIRHPPNPRLYPPGSLPQGAQYNISALVTIATKTFLRYDRLRALITSIR 300

Query: 285 EYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFL 344
            +YP +TV++ADDS KP  +   +VE+Y MPFGKGWFAGRNLA+SQVTTKYVLWVDDDF+
Sbjct: 301 RFYPTVTVVIADDSDKPERVSGPYVEHYLMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFV 360

Query: 345 FNEETKIEVLVDVLEKTELDVVGGSV---LGNVFQFKLLLEQSEN----GACLHKRMGFF 397
           F   T++E LVDVLE+T LD+VGG+V    G    ++ LL         G CL +R GF 
Sbjct: 361 FTARTRLERLVDVLERTPLDLVGGAVREISGFATTYRQLLSVEPGAPGLGNCLRQRRGFH 420

Query: 398 QPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVI 457
             L GFP CVVT GVVNFFLA T++++ VGFDPRL RVAH EFF+DGLG+L VGSC +V+
Sbjct: 421 HELVGFPGCVVTDGVVNFFLARTDKVREVGFDPRLSRVAHLEFFLDGLGSLRVGSCSDVV 480

Query: 458 IGHQSRSPVVDSELAALEKTYNTYR-SNTLTRVQF-KLALHYFKNHLQC 504
           + H S+  +  +   A  +TY  YR   +L   Q  K  L +FK+ LQC
Sbjct: 481 VDHASKLKLPWTSRDAGAETYARYRYPGSLDESQMAKHRLLFFKHRLQC 529


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 12/23 (52%), Positives = 14/23 (60%)

Query: 67  SYDGIWLFPKNQCKCEANKEQGG 89
           S DG WL P  +C CE   E+GG
Sbjct: 250 SPDGEWLVPVGRCHCEPGYEEGG 272


>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
          Length = 866

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 16/83 (19%)

Query: 82  EANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPL-LVQPNLP---FGY 137
           EA +EQ   N ++ + +   P  K       E  QR E LPRP+P  L QP +P   F +
Sbjct: 750 EAEEEQKRKNGENTFKRIGPPLEKP-----VEKVQRVEALPRPVPQNLPQPQMPPYAFAH 804

Query: 138 PVHGVEVM-------PLHTVPIP 153
           P   +  +       PL+  PIP
Sbjct: 805 PPFPLPPVRPVFNNFPLNMGPIP 827


>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
          Length = 923

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 16/83 (19%)

Query: 82  EANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPL-LVQPNLP---FGY 137
           EA +EQ   N ++ + +   P  K       E  QR E LPRP+P  L QP +P   F +
Sbjct: 807 EAEEEQKRKNGENTFKRIGPPLEKP-----VEKVQRVEALPRPVPQNLPQPQMPPYAFAH 861

Query: 138 PVHGVEVM-------PLHTVPIP 153
           P   +  +       PL+  PIP
Sbjct: 862 PPFPLPPVRPVFNNFPLNMGPIP 884


>gi|222136639 methylenetetrahydrofolate dehydrogenase 1 [Homo
           sapiens]
          Length = 935

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 13/84 (15%)

Query: 43  ELPSPAPGVQKLKLLPEERLR----NLFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQ 98
           + PS    +  LKL  E+++R     ++  D I L P+ Q K E   +QG  N       
Sbjct: 807 QAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFGN------- 859

Query: 99  SDLPAVKARRQAEFEHFQRREGLP 122
             LP   A+      H   ++G+P
Sbjct: 860 --LPICMAKTHLSLSHNPEQKGVP 881


>gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
          Length = 631

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 14/36 (38%), Positives = 22/36 (61%)

Query: 324 RNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLE 359
           R+ ++SQ    Y L  DDDF+  +E  I+ +VD+ E
Sbjct: 139 RSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSE 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,975,269
Number of Sequences: 37866
Number of extensions: 958644
Number of successful extensions: 2320
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2310
Number of HSP's gapped (non-prelim): 10
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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