Guide to the Human Genome
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Search of human proteins with 22749497

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749497 hypothetical protein LOC254158 [Homo sapiens]
         (332 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749497 hypothetical protein LOC254158 [Homo sapiens]             670   0.0  
gi|115298676 hypothetical protein LOC160140 [Homo sapiens]             54   3e-07
gi|50658082 centrosomal protein 70 kDa [Homo sapiens]                  32   0.79 
gi|116805340 glycyl-tRNA synthetase [Homo sapiens]                     31   1.3  
gi|4757930 cyclin B2 [Homo sapiens]                                    29   5.1  
gi|126012573 low density lipoprotein-related protein 2 [Homo sap...    28   8.7  
gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a [...    28   8.7  
gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b [...    28   8.7  

>gi|22749497 hypothetical protein LOC254158 [Homo sapiens]
          Length = 332

 Score =  670 bits (1729), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MNRSSNVPRKGILKSGTRSLQKVCRVHFANARNARSLLSMLKDISAQIIQRAWLSHTNKM 60
           MNRSSNVPRKGILKSGTRSLQKVCRVHFANARNARSLLSMLKDISAQIIQRAWLSHTNKM
Sbjct: 1   MNRSSNVPRKGILKSGTRSLQKVCRVHFANARNARSLLSMLKDISAQIIQRAWLSHTNKM 60

Query: 61  IFRLLKHAICAAEFYVTHEILKKVAPLEAKLIKDPTMQCKIRFRFRGETFPPFIVFKIFL 120
           IFRLLKHAICAAEFYVTHEILKKVAPLEAKLIKDPTMQCKIRFRFRGETFPPFIVFKIFL
Sbjct: 61  IFRLLKHAICAAEFYVTHEILKKVAPLEAKLIKDPTMQCKIRFRFRGETFPPFIVFKIFL 120

Query: 121 HTDGHGYKYFSGKNVLMPSSKAVDDACKLMGERKFHRIIMEDERIFPKSKVTDIMDVVTM 180
           HTDGHGYKYFSGKNVLMPSSKAVDDACKLMGERKFHRIIMEDERIFPKSKVTDIMDVVTM
Sbjct: 121 HTDGHGYKYFSGKNVLMPSSKAVDDACKLMGERKFHRIIMEDERIFPKSKVTDIMDVVTM 180

Query: 181 QDYVQYRSFFDEAPAFSGGRNNSWRKLNLENIPRTMLMYDIVHYSESGVISNRLRNEMKF 240
           QDYVQYRSFFDEAPAFSGGRNNSWRKLNLENIPRTMLMYDIVHYSESGVISNRLRNEMKF
Sbjct: 181 QDYVQYRSFFDEAPAFSGGRNNSWRKLNLENIPRTMLMYDIVHYSESGVISNRLRNEMKF 240

Query: 241 LLQRPVTQEIHKHQLRIVSEIRGPYLTVQPLYRPYKQQNQVKFLGRRSKQAQMKVEKMRK 300
           LLQRPVTQEIHKHQLRIVSEIRGPYLTVQPLYRPYKQQNQVKFLGRRSKQAQMKVEKMRK
Sbjct: 241 LLQRPVTQEIHKHQLRIVSEIRGPYLTVQPLYRPYKQQNQVKFLGRRSKQAQMKVEKMRK 300

Query: 301 VYLAKEKNTSEVTEPKTGPSGTKDNYHLHSIF 332
           VYLAKEKNTSEVTEPKTGPSGTKDNYHLHSIF
Sbjct: 301 VYLAKEKNTSEVTEPKTGPSGTKDNYHLHSIF 332


>gi|115298676 hypothetical protein LOC160140 [Homo sapiens]
          Length = 313

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 31/80 (38%), Positives = 44/80 (55%), Gaps = 1/80 (1%)

Query: 42  KDISAQIIQRAWLSHTNKMIFRLLKHAICAAEFYVTHEILKKVAPLEAKLIKDPTMQCKI 101
           +D +A++IQ+AW S  N  IF+  K  I         +I+K + P EA+L+ D      +
Sbjct: 12  QDKAARVIQQAWKSFLNVAIFQHFKSLIDLRRQGEPRQIVKYINPKEAELL-DAAAGIHV 70

Query: 102 RFRFRGETFPPFIVFKIFLH 121
           RFR  G  FPP I +KIF H
Sbjct: 71  RFRLGGVKFPPDIYYKIFTH 90


>gi|50658082 centrosomal protein 70 kDa [Homo sapiens]
          Length = 597

 Score = 32.0 bits (71), Expect = 0.79
 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 231 SNRLRNEMKFLLQRPVTQEIHKHQL-RIVSEIRGPY--LTVQPLYRPYKQQNQVKFLGRR 287
           + +LRNE++    R   QE   + L +I+  ++     L  + L R   QQN++K L + 
Sbjct: 91  NQQLRNELQLEQSRAANQEQRANDLEQIMESVKSKIGELEDESLSRACHQQNKIKDLQKE 150

Query: 288 SKQAQMKVEKMRKVYLAKEKNTSEV 312
            K  Q+K +  +K    +E+  + +
Sbjct: 151 QKTLQVKCQHYKKKRTEQEETIASL 175


>gi|116805340 glycyl-tRNA synthetase [Homo sapiens]
          Length = 739

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 1/55 (1%)

Query: 145 DACKLMGERKFHRIIMEDERIFPKSKVTDIMDVVTMQDYVQYRSFFDEAPAFSGG 199
           D  K + E K  + ++E + +  + K  DI+D   M+D ++ R F+D+A A  GG
Sbjct: 90  DVDKAVAELKARKRVLEAKELALQPK-DDIVDRAKMEDTLKRRFFYDQAFAIYGG 143


>gi|4757930 cyclin B2 [Homo sapiens]
          Length = 398

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 15/113 (13%)

Query: 215 TMLMYDIVHYSESGV------ISNRLRNEMKF-LLQRPVTQEIHKHQLRIVSEIRGPYLT 267
           T++ YD+VHY  S V      +S ++  + K+ L Q+  T       L ++  +    + 
Sbjct: 294 TLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVK 353

Query: 268 VQPLYRPYKQQNQVKFLGRRSKQAQMKVEKMRKVYLAKEKNTSEVTEPKTGPS 320
           V         +N  KF+  ++K A  K+ K+  +     K   ++  P  G S
Sbjct: 354 V--------NENLTKFIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS 398


>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
          Length = 4655

 Score = 28.5 bits (62), Expect = 8.7
 Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 43   DISAQIIQRAWLSHTNKMIFRLLKHAICAAEFYVTHEILKKVAPLEAKL 91
            D   Q+I+R +L+ TNK    ++ H + AAE      + +K+  L+A+L
Sbjct: 3245 DTQRQVIERMFLNKTNKE--TIINHRLPAAESLAVDWVSRKLYWLDARL 3291


>gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a
           [Homo sapiens]
          Length = 690

 Score = 28.5 bits (62), Expect = 8.7
 Identities = 13/63 (20%), Positives = 28/63 (44%), Gaps = 1/63 (1%)

Query: 120 LHTDGHGYKYFSGKNVLMPSSKAVDDACKLMGERKFHRIIMEDERI-FPKSKVTDIMDVV 178
           LH+  H Y +  G    +  ++ + D   +  E  +  + M+D+ + F    V ++MD  
Sbjct: 168 LHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDAT 227

Query: 179 TMQ 181
             +
Sbjct: 228 NRE 230


>gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b
           [Homo sapiens]
          Length = 670

 Score = 28.5 bits (62), Expect = 8.7
 Identities = 13/63 (20%), Positives = 28/63 (44%), Gaps = 1/63 (1%)

Query: 120 LHTDGHGYKYFSGKNVLMPSSKAVDDACKLMGERKFHRIIMEDERI-FPKSKVTDIMDVV 178
           LH+  H Y +  G    +  ++ + D   +  E  +  + M+D+ + F    V ++MD  
Sbjct: 168 LHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDAT 227

Query: 179 TMQ 181
             +
Sbjct: 228 NRE 230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,971,854
Number of Sequences: 37866
Number of extensions: 478060
Number of successful extensions: 1170
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1167
Number of HSP's gapped (non-prelim): 8
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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