Search of human proteins with 22749415

Search of human proteins with 22749415

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749415 integral membrane protein 1 [Homo sapiens]
         (705 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749415 integral membrane protein 1 [Homo sapiens]               1431   0.0  
gi|30578410 source of immunodominant MHC-associated peptides [Ho...   867   0.0  
gi|169164947 PREDICTED: similar to mal, T-cell differentiation p...    33   0.69 
gi|169164253 PREDICTED: similar to mal, T-cell differentiation p...    33   0.69 
gi|169163277 PREDICTED: similar to mal, T-cell differentiation p...    33   0.69 
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s...    32   2.6  
gi|52353286 olfactory receptor, family 8, subfamily B, member 4 ...    32   2.6  
gi|155030242 WD repeat domain 60 [Homo sapiens]                        31   3.4  
gi|4502809 chitotriosidase [Homo sapiens]                              30   7.7  
gi|171906582 coiled-coil domain containing 47 [Homo sapiens]           30   7.7  

>gi|22749415 integral membrane protein 1 [Homo sapiens]
          Length = 705

 Score = 1431 bits (3705), Expect = 0.0
 Identities = 705/705 (100%), Positives = 705/705 (100%)

Query: 1   MTKFGFLRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFL 60
           MTKFGFLRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFL
Sbjct: 1   MTKFGFLRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFL 60

Query: 61  AEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLA 120
           AEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLA
Sbjct: 61  AEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLA 120

Query: 121 PLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTY 180
           PLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTY
Sbjct: 121 PLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTY 180

Query: 181 YMWIKAVKTGSICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAY 240
           YMWIKAVKTGSICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAY
Sbjct: 181 YMWIKAVKTGSICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAY 240

Query: 241 CTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFR 300
           CTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFR
Sbjct: 241 CTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFR 300

Query: 301 SVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSY 360
           SVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSY
Sbjct: 301 SVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSY 360

Query: 361 YFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGI 420
           YFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGI
Sbjct: 361 YFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGI 420

Query: 421 GVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTS 480
           GVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTS
Sbjct: 421 GVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTS 480

Query: 481 EAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTI 540
           EAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTI
Sbjct: 481 EAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTI 540

Query: 541 LVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMV 600
           LVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMV
Sbjct: 541 LVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMV 600

Query: 601 RIGGSTDTGKHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGF 660
           RIGGSTDTGKHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGF
Sbjct: 601 RIGGSTDTGKHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGF 660

Query: 661 DRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLDNRGLSRT 705
           DRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLDNRGLSRT
Sbjct: 661 DRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLDNRGLSRT 705


>gi|30578410 source of immunodominant MHC-associated peptides [Homo
           sapiens]
          Length = 826

 Score =  867 bits (2240), Expect = 0.0
 Identities = 428/712 (60%), Positives = 531/712 (74%), Gaps = 30/712 (4%)

Query: 16  TLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDR 75
           +LL   IL +A +  FS+RLFAV+RFES+IHEFDP+FNYR+T  LA  GFY+F NWFD+R
Sbjct: 70  SLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFDER 129

Query: 76  AWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLT 135
           AWYPLGRI+GGT+YPGLMIT+  I+ +L+  +IT+ IR+VCVFLAP FS  T+I T+ LT
Sbjct: 130 AWYPLGRIVGGTVYPGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSISTFLLT 189

Query: 136 KELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSICWA 195
           +EL + GAGLLAA  IA+VPGYISRSVAGS+DNEGIAIF +  TYY+W+K+VKTGS+ W 
Sbjct: 190 RELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWT 249

Query: 196 AKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQIS 255
             C L+YFYMVS+WGGYVF+INLIPLHV VL+L  R+S R+Y+AY T Y +G ILSMQI 
Sbjct: 250 MCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIP 309

Query: 256 FVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFRSVISL-VGFVLLTVG 314
           FVGFQP+ +SEHMAA GVF L Q +AF+ YLR +L  Q+F+ LF   +SL  G V L+V 
Sbjct: 310 FVGFQPIRTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSV- 368

Query: 315 ALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVG 374
             L  TG I+PW+GRFYSL D  YAK +IPIIASVSEHQPTTW S++FDL +LV  FP G
Sbjct: 369 IYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAG 428

Query: 375 LYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLD 434
           L++C  N++D R+F+ +Y ++++YF+ VMVRLML L PV+C+LS I  S V   Y+ + D
Sbjct: 429 LWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLGD-D 487

Query: 435 ISRP--------------------DKKSKKQQDSTYPIKNE------VASGMILVMAFFL 468
           + R                     DK  K ++ +T   K E      + S + ++M   L
Sbjct: 488 MKRENPPVEDSSDEDDKRNQGNLYDKAGKVRKHATEQEKTEEGLGPNIKSIVTMLMLMLL 547

Query: 469 ITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDY 528
           + +  H TWVTS AYSSPS+VL++   DG+R I DDFREAY+WLR NT E A+VMSWWDY
Sbjct: 548 MMFAVHCTWVTSNAYSSPSVVLASYNHDGTRNILDDFREAYFWLRQNTDEHARVMSWWDY 607

Query: 529 GYQITAMANRTILVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGY 588
           GYQI  MANRT LVDNNTWNN+HI+ VG+AM+S E  AY+IMR LDV YVLVIFGG+ GY
Sbjct: 608 GYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNETAAYKIMRTLDVDYVLVIFGGVIGY 667

Query: 589 SSDDINKFLWMVRIGGSTDTGKHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFG 648
           S DDINKFLWMVRI    +  K I+E+DY+TP GEFRVD+ GSP LLNCLMYKM YYRFG
Sbjct: 668 SGDDINKFLWMVRI-AEGEHPKDIRESDYFTPQGEFRVDKAGSPTLLNCLMYKMSYYRFG 726

Query: 649 QVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLDNR 700
           ++  + + PPGFDR RNAEIGNKD +   LEEA+T+EHWLVRIYKVK  DNR
Sbjct: 727 EMQLDFRTPPGFDRTRNAEIGNKDIKFKHLEEAFTSEHWLVRIYKVKAPDNR 778


>gi|169164947 PREDICTED: similar to mal, T-cell differentiation
           protein-like [Homo sapiens]
          Length = 130

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 11/68 (16%)

Query: 72  FDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITI-----DIRNVCVFLAPLFSSF 126
           F   +W  L  +  GT   G++  SAA+  V    H+ I     D+RN C+  A LF +F
Sbjct: 61  FGFESWRVLDSLYHGTT--GILYMSAAVLQV----HVMIMSEAQDLRNYCINTAALFFAF 114

Query: 127 TTIVTYHL 134
            T++ Y L
Sbjct: 115 VTMLLYIL 122


>gi|169164253 PREDICTED: similar to mal, T-cell differentiation
           protein-like [Homo sapiens]
          Length = 130

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 11/68 (16%)

Query: 72  FDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITI-----DIRNVCVFLAPLFSSF 126
           F   +W  L  +  GT   G++  SAA+  V    H+ I     D+RN C+  A LF +F
Sbjct: 61  FGFESWRVLDSLYHGTT--GILYMSAAVLQV----HVMIMSEAQDLRNYCINTAALFFAF 114

Query: 127 TTIVTYHL 134
            T++ Y L
Sbjct: 115 VTMLLYIL 122


>gi|169163277 PREDICTED: similar to mal, T-cell differentiation
           protein-like [Homo sapiens]
          Length = 130

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 11/68 (16%)

Query: 72  FDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITI-----DIRNVCVFLAPLFSSF 126
           F   +W  L  +  GT   G++  SAA+  V    H+ I     D+RN C+  A LF +F
Sbjct: 61  FGFESWRVLDSLYHGTT--GILYMSAAVLQV----HVMIMSEAQDLRNYCINTAALFFAF 114

Query: 127 TTIVTYHL 134
            T++ Y L
Sbjct: 115 VTMLLYIL 122


>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
           sapiens]
          Length = 658

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 328 GRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARI 387
           G  +  L    +K   PIIA++S        ++ FDL+ LV M  +G    +S L  A +
Sbjct: 371 GLLFKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYS-LVAACV 429

Query: 388 FIIMY 392
            I+ Y
Sbjct: 430 LILRY 434


>gi|52353286 olfactory receptor, family 8, subfamily B, member 4
           [Homo sapiens]
          Length = 309

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 17/53 (32%), Positives = 30/53 (56%), Gaps = 1/53 (1%)

Query: 378 CFSNLSDARIFIIMYGVTSMYFS-AVMVRLMLVLAPVMCILSGIGVSQVLSTY 429
           C S      +F I+ GV +M  S ++++   L+L+ ++CI S  G S+  ST+
Sbjct: 188 CTSTHVSELVFFIVVGVITMLSSISIVISYALILSNILCIPSAEGRSKAFSTW 240


>gi|155030242 WD repeat domain 60 [Homo sapiens]
          Length = 1066

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 5/98 (5%)

Query: 588 YSSDDINKFLWMVRIGGSTDTGKHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRF 647
           + +DD+ K LW ++ GGS +  KH ++        E  +     P   +         R 
Sbjct: 13  WKADDLRKHLWAIQSGGSKEERKHREKK--LRKESEMDLPEHKEPRCRDPDQDARSRDRV 70

Query: 648 GQVYTEAKRPPG---FDRVRNAEIGNKDFELDVLEEAY 682
            +V+T  + P G    DR R      KD E + L+E +
Sbjct: 71  AEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKH 108


>gi|4502809 chitotriosidase [Homo sapiens]
          Length = 466

 Score = 30.0 bits (66), Expect = 7.7
 Identities = 16/66 (24%), Positives = 25/66 (37%), Gaps = 2/66 (3%)

Query: 468 LITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWD 527
           L+ Y FH +W     ++SP        G  + +  D       WL+  TP    ++    
Sbjct: 209 LMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVD--AAVQQWLQKGTPASKLILGMPT 266

Query: 528 YGYQIT 533
           YG   T
Sbjct: 267 YGRSFT 272


>gi|171906582 coiled-coil domain containing 47 [Homo sapiens]
          Length = 483

 Score = 30.0 bits (66), Expect = 7.7
 Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 335 DPSYAKNNIPI-IASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARI 387
           D S +KN  PI I  V  H   +W SYY ++ ++  +    + Y      ++R+
Sbjct: 110 DTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRL 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,741,002
Number of Sequences: 37866
Number of extensions: 1052983
Number of successful extensions: 2457
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2451
Number of HSP's gapped (non-prelim): 10
length of query: 705
length of database: 18,247,518
effective HSP length: 109
effective length of query: 596
effective length of database: 14,120,124
effective search space: 8415593904
effective search space used: 8415593904
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.