Guide to the Human Genome
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Search of human proteins with 22749199

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749199 fragile X mental retardation 1 neighbor [Homo
sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749199 fragile X mental retardation 1 neighbor [Homo sapiens]    525   e-149
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]     29   3.5  
gi|100913200 ephrin A4 isoform c [Homo sapiens]                        29   3.5  
gi|33359686 ephrin A4 isoform b [Homo sapiens]                         29   3.5  
gi|4885197 ephrin A4 isoform a [Homo sapiens]                          29   3.5  
gi|22748973 protein interacting with cyclin A1 [Homo sapiens]          29   4.6  

>gi|22749199 fragile X mental retardation 1 neighbor [Homo sapiens]
          Length = 255

 Score =  525 bits (1352), Expect = e-149
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MSSHRRKAKGRNRRSHRAMRVAHLELATYELAATESNPESSHPGYEAAMADRPQPGWRES 60
           MSSHRRKAKGRNRRSHRAMRVAHLELATYELAATESNPESSHPGYEAAMADRPQPGWRES
Sbjct: 1   MSSHRRKAKGRNRRSHRAMRVAHLELATYELAATESNPESSHPGYEAAMADRPQPGWRES 60

Query: 61  LKMRVSKPFGMLMLSIWILLFVCYYLSYYLCSGSSYFVLANGHILPNSENAHGQSLEEDS 120
           LKMRVSKPFGMLMLSIWILLFVCYYLSYYLCSGSSYFVLANGHILPNSENAHGQSLEEDS
Sbjct: 61  LKMRVSKPFGMLMLSIWILLFVCYYLSYYLCSGSSYFVLANGHILPNSENAHGQSLEEDS 120

Query: 121 ALEALLNFFFPTTCNLRENQVAKPCNELQDLSESECLRHKCCFSSSGTTSFKCFAPFRDV 180
           ALEALLNFFFPTTCNLRENQVAKPCNELQDLSESECLRHKCCFSSSGTTSFKCFAPFRDV
Sbjct: 121 ALEALLNFFFPTTCNLRENQVAKPCNELQDLSESECLRHKCCFSSSGTTSFKCFAPFRDV 180

Query: 181 PKQMMQMFGLGAISLILVCLPIYCRSLFWRSEPADDLQRQDNRVVTGLKKQRRKRKRKSE 240
           PKQMMQMFGLGAISLILVCLPIYCRSLFWRSEPADDLQRQDNRVVTGLKKQRRKRKRKSE
Sbjct: 181 PKQMMQMFGLGAISLILVCLPIYCRSLFWRSEPADDLQRQDNRVVTGLKKQRRKRKRKSE 240

Query: 241 MLQKAARGREEHGDE 255
           MLQKAARGREEHGDE
Sbjct: 241 MLQKAARGREEHGDE 255


>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
          Length = 845

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 33/144 (22%), Positives = 50/144 (34%), Gaps = 8/144 (5%)

Query: 114 QSLEEDSALEALLNFFFPTTCNLRENQVAKPCNELQDLSESECLRHKCC--FSSSGTTSF 171
           Q+L +   L  LLN   P   NLRE  +    ++   L         CC  F    +  F
Sbjct: 35  QALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELF 94

Query: 172 KCFAPFRDVPKQMMQMFGLGAISLILVCLPIYCRSLFWRSEPADDLQRQDNRVVTGLKKQ 231
           + F  F       +Q FG    +L  +      ++      P ++    D  + +GL  Q
Sbjct: 95  EAFDLFD------VQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVGDEDIYSGLSDQ 148

Query: 232 RRKRKRKSEMLQKAARGREEHGDE 255
                 + E L       E  GDE
Sbjct: 149 IDDTVEEDEDLYDCVENEEAEGDE 172


>gi|100913200 ephrin A4 isoform c [Homo sapiens]
          Length = 193

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 9/74 (12%)

Query: 43  PGYEAAMADRPQPGWRESLKMRVSKPFGMLMLSIWILLFVCYYLSYYLCSGSSYFVLANG 102
           PGYE+  A+ P    R   +   S PFG +  S  I  F  + L +    G +Y+ ++  
Sbjct: 81  PGYESCQAEGP----RAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYIS-- 134

Query: 103 HILPNSENAHGQSL 116
             +P  E++ GQ L
Sbjct: 135 --VPTPESS-GQCL 145


>gi|33359686 ephrin A4 isoform b [Homo sapiens]
          Length = 207

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 9/74 (12%)

Query: 43  PGYEAAMADRPQPGWRESLKMRVSKPFGMLMLSIWILLFVCYYLSYYLCSGSSYFVLANG 102
           PGYE+  A+ P    R   +   S PFG +  S  I  F  + L +    G +Y+ ++  
Sbjct: 81  PGYESCQAEGP----RAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYIS-- 134

Query: 103 HILPNSENAHGQSL 116
             +P  E++ GQ L
Sbjct: 135 --VPTPESS-GQCL 145


>gi|4885197 ephrin A4 isoform a [Homo sapiens]
          Length = 201

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 9/74 (12%)

Query: 43  PGYEAAMADRPQPGWRESLKMRVSKPFGMLMLSIWILLFVCYYLSYYLCSGSSYFVLANG 102
           PGYE+  A+ P    R   +   S PFG +  S  I  F  + L +    G +Y+ ++  
Sbjct: 81  PGYESCQAEGP----RAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYIS-- 134

Query: 103 HILPNSENAHGQSL 116
             +P  E++ GQ L
Sbjct: 135 --VPTPESS-GQCL 145


>gi|22748973 protein interacting with cyclin A1 [Homo sapiens]
          Length = 336

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)

Query: 209 WRSEPADDLQRQDNRVVTGLKKQRRKRKRKSEMLQKA 245
           WRSE     + Q ++V+  +KK++ K K K EM +KA
Sbjct: 190 WRSESPTG-KGQGSKVIKKVKKKKEKEKDKEEMDEKA 225


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.133    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,065,039
Number of Sequences: 37866
Number of extensions: 435527
Number of successful extensions: 1699
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1697
Number of HSP's gapped (non-prelim): 6
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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