Guide to the Human Genome
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Search of human proteins with 22749079

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749079 MURR1 [Homo sapiens]
         (190 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749079 MURR1 [Homo sapiens]                                      377   e-105
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]           44   8e-05
gi|21361661 COMM domain containing 4 [Homo sapiens]                    36   0.023
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   33   0.15 
gi|45545435 COMM domain containing 2 [Homo sapiens]                    30   1.6  
gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]         28   4.8  
gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]         28   4.8  
gi|156139155 guanine nucleotide binding protein, alpha transduci...    28   6.2  
gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo s...    27   8.1  
gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]             27   8.1  
gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]             27   8.1  

>gi|22749079 MURR1 [Homo sapiens]
          Length = 190

 Score =  377 bits (967), Expect = e-105
 Identities = 190/190 (100%), Positives = 190/190 (100%)

Query: 1   MAAGELEGGKPLSGLLNALAQDTFHGYPGITEELLRSQLYPEVPPEEFRPFLAKMRGILK 60
           MAAGELEGGKPLSGLLNALAQDTFHGYPGITEELLRSQLYPEVPPEEFRPFLAKMRGILK
Sbjct: 1   MAAGELEGGKPLSGLLNALAQDTFHGYPGITEELLRSQLYPEVPPEEFRPFLAKMRGILK 60

Query: 61  SIASADMDFNQLEAFLTAQTKKQGGITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLR 120
           SIASADMDFNQLEAFLTAQTKKQGGITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLR
Sbjct: 61  SIASADMDFNQLEAFLTAQTKKQGGITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLR 120

Query: 121 GLSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLCLEFDEVKVNQILKTLSEVEE 180
           GLSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLCLEFDEVKVNQILKTLSEVEE
Sbjct: 121 GLSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLCLEFDEVKVNQILKTLSEVEE 180

Query: 181 SISTLISQPN 190
           SISTLISQPN
Sbjct: 181 SISTLISQPN 190


>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
          Length = 602

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 51/175 (29%), Positives = 82/175 (46%), Gaps = 26/175 (14%)

Query: 30  ITEELLRSQLYPEVPPEEFRPFLAKMRGILKSIA---SADMDFNQLEAFLTAQTKKQG-- 84
           +TE+LLRS+      PEE R    ++R  LKS +     D  F   EAF   Q K QG  
Sbjct: 352 LTEKLLRSEESVSRLPEEIRRLEEELRQ-LKSDSHGPKEDGGFRHSEAFEALQQKSQGLD 410

Query: 85  --------GITSDQAAVISKFWKSHKTKIRESLMNQSR-WNSGLRGLSWRVD--GKSQSR 133
                   G+ S Q A       + +T+  ESL+++S+     L  L  R++  G S++ 
Sbjct: 411 SRLQHVEDGVLSMQVA------SARQTESLESLLSKSQEHEQRLAALQGRLEGLGSSEAD 464

Query: 134 HSAQIHTPVAIIELELGKYGQESEFLCLEFDEVKVNQILKTLSEVEESISTLISQ 188
                 T  ++ E +L  YG   E   L+    ++   +++L +V+E + TL+SQ
Sbjct: 465 QDGLASTVRSLGETQLVLYGDVEE---LKRSVGELPSTVESLQKVQEQVHTLLSQ 516


>gi|21361661 COMM domain containing 4 [Homo sapiens]
          Length = 199

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 32/155 (20%), Positives = 69/155 (44%), Gaps = 6/155 (3%)

Query: 32  EELLRSQLYPEVPPEEFRPFLAKMRGILKSIASADMDFNQLEAFLTAQTKKQGGITSDQA 91
           E++L+     +    + +  +A +  IL S A   +D   L + L     +Q G+  + A
Sbjct: 49  EKILKLTADAKFESGDVKATVAVLSFILSSAAKHSVDGESLSSEL-----QQLGLPKEHA 103

Query: 92  AVISKFWKSHKTKIRESLMNQSRWNSGLRGLSWRVDGKSQSRHSAQIHTPVAIIELELGK 151
           A + + ++  ++ +++ L   S   + L G+ WRVD    S     +  P+  + LE+  
Sbjct: 104 ASLCRCYEEKQSPLQKHLRVCSLRMNRLAGVGWRVDYTLSSSLLQSVEEPMVHLRLEVAA 163

Query: 152 Y-GQESEFLCLEFDEVKVNQILKTLSEVEESISTL 185
             G  ++ + +     K   +L  L + +  +S+L
Sbjct: 164 APGTPAQPVAMSLSADKFQVLLAELKQAQTLMSSL 198


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 39/176 (22%), Positives = 80/176 (45%), Gaps = 21/176 (11%)

Query: 27  YPGITEELLRSQLYPEVPPEEFRPFLAKMRGILKSIASADMDFNQLEAFLTAQTKK---- 82
           Y  I E+L R +       E++R  +   + +  S+ + +M+   +++ L    ++    
Sbjct: 809 YEKIREQLRRKE-------EQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDA 861

Query: 83  QGGITSDQAAVISK--FWKSHKTKIRESLMNQSRWNSGLRGLSWRVDGKSQSRHSAQIHT 140
           Q  ++ +Q A + +     +H +K +E  M Q + NS         + K  S  ++ +  
Sbjct: 862 QRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNS--ENSHSHEEEKDLSHKNSMLQE 919

Query: 141 PVAIIELELG---KYGQESEFLCLEFDEV---KVNQILKTLSEVEESISTLISQPN 190
            +A++ LE+       QE E  C E  ++   K   + KT+ + EE+++  ISQ N
Sbjct: 920 EIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYN 975


>gi|45545435 COMM domain containing 2 [Homo sapiens]
          Length = 199

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 21/100 (21%), Positives = 44/100 (44%), Gaps = 1/100 (1%)

Query: 85  GITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLRGLSWRVDGKSQSRHSAQIHTPVAI 144
           G + +   ++ + +  ++ +IR  L   +        L WR+D +  SR   Q   P   
Sbjct: 90  GFSEELNKLLLQLYLDNRKEIRTILSELAPSLPSYHNLEWRLDVQLASRSLRQQIKPAVT 149

Query: 145 IELELGKYGQESEFLCLEFDEVKVNQILKTLSEVEESIST 184
           I+L L + G  +  + L+ D   +  +++ L +  E + T
Sbjct: 150 IKLHLNQNGDHNTKV-LQTDPATLLHLVQQLEQALEEMKT 188


>gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]
          Length = 156

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 17/77 (22%), Positives = 37/77 (48%), Gaps = 14/77 (18%)

Query: 122 LSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLC----------LEFDEVKVNQI 171
           L WRVD K+ S   +++  P  ++++++    QE   LC          +E  +  ++ +
Sbjct: 84  LDWRVDIKTSSDSISRMAVPTCLLQMKI----QEDPSLCGDKPSISAVTVELSKETLDTM 139

Query: 172 LKTLSEVEESISTLISQ 188
           L  L  + + +S + S+
Sbjct: 140 LDGLGRIRDQLSAVASK 156


>gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]
          Length = 198

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 17/77 (22%), Positives = 37/77 (48%), Gaps = 14/77 (18%)

Query: 122 LSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLC----------LEFDEVKVNQI 171
           L WRVD K+ S   +++  P  ++++++    QE   LC          +E  +  ++ +
Sbjct: 126 LDWRVDIKTSSDSISRMAVPTCLLQMKI----QEDPSLCGDKPSISAVTVELSKETLDTM 181

Query: 172 LKTLSEVEESISTLISQ 188
           L  L  + + +S + S+
Sbjct: 182 LDGLGRIRDQLSAVASK 198


>gi|156139155 guanine nucleotide binding protein, alpha transducing
           3 [Homo sapiens]
          Length = 354

 Score = 27.7 bits (60), Expect = 6.2
 Identities = 14/55 (25%), Positives = 28/55 (50%), Gaps = 7/55 (12%)

Query: 52  LAKMRGILKSIASADMDF-------NQLEAFLTAQTKKQGGITSDQAAVISKFWK 99
           L  +  I+K++ +  +D+       +Q + +  A T + GG+T   A VI + W+
Sbjct: 78  LQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLEDGGMTPQLAEVIKRLWR 132


>gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo
           sapiens]
          Length = 522

 Score = 27.3 bits (59), Expect = 8.1
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 16  LNALAQDTFHGYPGITEELLRSQLYPEVPPEEFRPFLAKMRGILKSIASADMDFNQLEA 74
           L ALA D FHG   +T   +R+     VP   F+          +S+   D+ +NQL++
Sbjct: 149 LQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD--------CRSLKFLDIGYNQLKS 199


>gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]
          Length = 1027

 Score = 27.3 bits (59), Expect = 8.1
 Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 18/106 (16%)

Query: 32  EELLRSQLYPEV-----------PPEEFRPFLAK--MRGILKSIASADMDFNQLEAFLTA 78
           E+ LR+   PEV           P  E    L +  +  +L+  A   M  N     L  
Sbjct: 306 EKFLRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLIN-----LPG 360

Query: 79  QTKKQGGITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLRGLSW 124
           Q  K     S+ A  I   WK +K +       Q +W SG+  ++W
Sbjct: 361 QRYKGQDGNSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAW 406


>gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]
          Length = 621

 Score = 27.3 bits (59), Expect = 8.1
 Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 18/106 (16%)

Query: 32  EELLRSQLYPEV-----------PPEEFRPFLAK--MRGILKSIASADMDFNQLEAFLTA 78
           E+ LR+   PEV           P  E    L +  +  +L+  A   M  N     L  
Sbjct: 58  EKFLRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLIN-----LPG 112

Query: 79  QTKKQGGITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLRGLSW 124
           Q  K     S+ A  I   WK +K +       Q +W SG+  ++W
Sbjct: 113 QRYKGQDGNSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAW 158


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,796,666
Number of Sequences: 37866
Number of extensions: 261744
Number of successful extensions: 535
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 533
Number of HSP's gapped (non-prelim): 12
length of query: 190
length of database: 18,247,518
effective HSP length: 96
effective length of query: 94
effective length of database: 14,612,382
effective search space: 1373563908
effective search space used: 1373563908
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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