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Search of human proteins with 22748943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22748943 hypothetical protein LOC145483 [Homo sapiens]
(647 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22748943 hypothetical protein LOC145483 [Homo sapiens] 1276 0.0
gi|187936946 hypothetical protein LOC84140 [Homo sapiens] 169 7e-42
gi|154759273 testis specific, 10 interacting protein [Homo sapiens] 62 2e-09
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 59 1e-08
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 59 1e-08
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 59 1e-08
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 59 1e-08
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 59 1e-08
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 59 1e-08
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 59 1e-08
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 59 1e-08
gi|148746195 trichohyalin [Homo sapiens] 52 2e-06
gi|38788274 bromodomain PHD finger transcription factor isoform ... 47 4e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 46 9e-05
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 45 2e-04
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 44 6e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 44 6e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 42 0.001
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 42 0.002
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 42 0.002
gi|32484977 angiomotin like 2 [Homo sapiens] 42 0.002
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 41 0.003
gi|216548091 leucine zipper protein 1 [Homo sapiens] 40 0.007
gi|216548085 leucine zipper protein 1 [Homo sapiens] 40 0.007
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 40 0.007
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 40 0.007
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.009
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 40 0.009
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 39 0.011
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 39 0.011
>gi|22748943 hypothetical protein LOC145483 [Homo sapiens]
Length = 647
Score = 1276 bits (3303), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MTVGRPEGAPGGAEGSRQIFPPESFADTEAGEELSGDGLVLPRASKLDEFLSPEEEMDST 60
MTVGRPEGAPGGAEGSRQIFPPESFADTEAGEELSGDGLVLPRASKLDEFLSPEEEMDST
Sbjct: 1 MTVGRPEGAPGGAEGSRQIFPPESFADTEAGEELSGDGLVLPRASKLDEFLSPEEEMDST 60
Query: 61 SDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQC 120
SDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQC
Sbjct: 61 SDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQC 120
Query: 121 PQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLR 180
PQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLR
Sbjct: 121 PQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLR 180
Query: 181 EARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEAR 240
EARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEAR
Sbjct: 181 EARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEAR 240
Query: 241 RQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILE 300
RQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILE
Sbjct: 241 RQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILE 300
Query: 301 PALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHT 360
PALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHT
Sbjct: 301 PALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHT 360
Query: 361 NFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATT 420
NFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATT
Sbjct: 361 NFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATT 420
Query: 421 GRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESI 480
GRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESI
Sbjct: 421 GRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESI 480
Query: 481 QWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
QWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMK
Sbjct: 481 QWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF
Sbjct: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA 647
PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA
Sbjct: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA 647
>gi|187936946 hypothetical protein LOC84140 [Homo sapiens]
Length = 660
Score = 169 bits (428), Expect = 7e-42
Identities = 138/462 (29%), Positives = 222/462 (48%), Gaps = 82/462 (17%)
Query: 165 WASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAH 224
W +ITVP PF+M +RE +KK E + S + E + ++Q EE+ E ++FRA PVPA
Sbjct: 232 WVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQ-EEDPEYKKKFRANPVPAS 290
Query: 225 VYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAK 284
V+LPLY +++++ E RR++ +K KE LL+S KPF F+ +EEQ K AAR++ L + K
Sbjct: 291 VFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQ-KRAAREKQLRDFLKYK 349
Query: 285 ISKQK-ATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASS-PIASSSNRANP 342
+ R IP+S DKL+E EL+R +R Q+RA + LQ +S P S+ NP
Sbjct: 350 KKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNP 409
Query: 343 Q-PRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPF 401
+ P A + + + +V PD+E L + +Q+ ++ + + T KPF
Sbjct: 410 RCPEQAVK------------LKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPF 457
Query: 402 LLRTANLRHPQRPCDAATTGRRQDSPQPPATPL--PRSRS---LSGLASLSANTLPVHIT 456
L + +R A +++ + P PR +S +G+ + N P T
Sbjct: 458 DLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPT 517
Query: 457 DATRKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKA 516
++R RE AVR KS+ K
Sbjct: 518 VSSRGREQAVR---------------------KSE-----------------------KE 533
Query: 517 KLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLE 576
+++E + +R ++ KK RP LFE+VA+ A+ AE+ Y +TLK G+
Sbjct: 534 RMREYQRELEEREEKLKK-----------RPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
Query: 577 EDFVRNKGQGTRAV-----QEKETKIKDFPRFQETTKLSIRD 613
++FV KGQ + + QE ++ +D F E K+ R+
Sbjct: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERE 624
>gi|154759273 testis specific, 10 interacting protein [Homo sapiens]
Length = 556
Score = 61.6 bits (148), Expect = 2e-09
Identities = 47/179 (26%), Positives = 88/179 (49%), Gaps = 11/179 (6%)
Query: 461 KRESAVRSALEK-KNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEE-VFKAKL 518
KR+ A RS L+ + + E Q E+ R ++Q + + V A P S + KL
Sbjct: 378 KRQEATRSLLQAWERQRQEERQQAELRRARTQHVQRQVAHCLAAYAPRGSRGPGAAQRKL 437
Query: 519 KENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEED 578
+E R +R+R EY+ EL+ ++ R+Q RP+LF+Q + A+ + + L GL+E+
Sbjct: 438 EELRRQERQRFAEYQAELQGIQHRVQARPFLFQQAMQANARLTVTRRFSQVLSALGLDEE 497
Query: 579 FVRNKG-----QGT----RAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASP 628
+ ++ +GT R+ + +++ P+ T+ + P++ SL+ SP
Sbjct: 498 QLLSEAGKVDREGTPRKPRSHRSMGVRMEHSPQRPPRTEPTGSQPDRHYNPSLDPECSP 556
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1276 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1335
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1336 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1395
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1396 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1448
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1449 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1504
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1505 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1559
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1560 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1615
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1668
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1729 RQLLEE 1734
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1695 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1753
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1754 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1802
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1803 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1855
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1856 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 1915
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 1975
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 1976 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2032
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2033 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2091
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2128
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1733 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1792
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1793 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1850
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1851 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 1908
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 1909 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 1965
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2085
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2086 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2143
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2144 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2188
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2189 --TTLRLQLEETDHQ 2201
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 1948 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 2004
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2061
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2062 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2107
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2161
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2162 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2217
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2218 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2274
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2275 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2361
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2206 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2265
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2266 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2323 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2379
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2380 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2428
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2429 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2487
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2488 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2547
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2548 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2608 ALAHSEE 2614
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1280 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1339
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1340 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1399
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1400 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1452
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1453 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1508
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1509 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1563
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1564 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1619
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1620 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1672
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1673 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1732
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1733 RQLLEE 1738
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1699 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1757
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1758 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1806
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1807 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1859
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1860 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 1919
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 1920 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 1979
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 1980 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2036
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2037 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2095
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2096 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2132
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1737 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1796
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1797 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1854
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1855 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 1912
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 1913 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 1969
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 1970 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2029
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 2030 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2089
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2090 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2147
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2148 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2192
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2193 --TTLRLQLEETDHQ 2205
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 1952 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 2008
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 2009 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2065
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2066 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2111
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2112 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2165
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2166 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2221
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2222 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2278
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2279 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2326
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2365
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2210 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2269
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2270 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2326
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2327 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2383
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2384 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2432
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2433 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2491
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2492 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2551
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2552 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2611
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2612 ALAHSEE 2618
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1276 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1335
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1336 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1395
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1396 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1448
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1449 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1504
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1505 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1559
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1560 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1615
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1668
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1729 RQLLEE 1734
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1695 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1753
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1754 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1802
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1803 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1855
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1856 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 1915
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 1975
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 1976 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2032
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2033 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2091
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2128
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1733 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1792
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1793 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1850
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1851 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 1908
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 1909 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 1965
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2085
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2086 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2143
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2144 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2188
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2189 --TTLRLQLEETDHQ 2201
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 1948 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 2004
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2061
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2062 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2107
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2161
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2162 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2217
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2218 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2274
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2275 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2361
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2206 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2265
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2266 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2323 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2379
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2380 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2428
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2429 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2487
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2488 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2547
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2548 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2608 ALAHSEE 2614
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1244 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1303
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1304 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1363
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1364 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1416
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1417 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1472
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1473 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1527
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1528 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1583
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1584 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1636
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1637 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1696
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1697 RQLLEE 1702
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1663 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1721
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1722 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1770
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1771 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1823
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1824 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 1883
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 1884 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 1943
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 1944 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2000
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2001 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2059
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2060 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2096
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1701 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1760
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1761 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1818
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1819 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 1876
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 1877 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 1933
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 1934 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 1993
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 1994 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2053
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2054 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2111
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2112 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2156
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2157 --TTLRLQLEETDHQ 2169
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 1916 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 1972
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 1973 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2029
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2030 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2075
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2076 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2129
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2130 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2185
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2186 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2242
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2243 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2290
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2329
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2174 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2233
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2234 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2290
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2291 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2347
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2348 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2396
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2397 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2455
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2456 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2515
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2516 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2575
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2576 ALAHSEE 2582
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1413 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1472
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1473 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1532
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1533 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1585
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1586 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1641
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1642 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1696
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1697 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1752
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1753 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1805
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1806 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1865
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1866 RQLLEE 1871
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1832 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1890
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1891 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1939
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1940 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1992
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1993 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 2052
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 2053 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 2112
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 2113 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2169
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2170 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2228
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2229 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2265
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1870 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1929
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1930 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1987
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1988 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 2045
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 2046 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 2102
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 2103 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2162
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 2163 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2222
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2223 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2280
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2281 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2325
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2326 --TTLRLQLEETDHQ 2338
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 2085 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 2141
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 2142 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2198
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2199 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2244
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2245 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2298
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2299 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2354
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2355 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2411
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2412 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2498
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2343 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2402
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2403 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2460 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2516
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2517 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2565
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2566 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2624
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2625 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2684
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2685 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2744
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2745 ALAHSEE 2751
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1254 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1313
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1314 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1373
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1374 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1426
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1427 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1482
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1483 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1537
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1538 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1593
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1594 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1646
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1647 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1706
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1707 RQLLEE 1712
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1673 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1731
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1732 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1780
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1781 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1833
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1834 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 1893
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 1894 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 1953
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 1954 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2010
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2011 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2069
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2070 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2106
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1711 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1770
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1771 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1828
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1829 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 1886
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 1887 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 1943
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 1944 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2003
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 2004 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2063
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2064 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2121
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2122 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2166
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2167 --TTLRLQLEETDHQ 2179
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 1926 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 1982
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 1983 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2039
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2040 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2085
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2086 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2139
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2140 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2195
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2196 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2252
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2253 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2300
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2339
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2184 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2243
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2244 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2300
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2301 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2357
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2358 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2406
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2407 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2465
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2466 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2525
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2526 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2585
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2586 ALAHSEE 2592
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1262 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1321
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1322 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1381
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1382 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1434
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1435 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1490
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1491 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1545
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1546 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1601
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1602 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1654
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1655 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1714
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1715 RQLLEE 1720
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1681 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1739
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1740 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1788
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1789 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1841
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1842 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 1901
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 1902 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 1961
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 1962 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2018
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2019 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2077
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2078 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2114
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1719 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1778
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1779 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1836
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1837 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 1894
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 1895 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 1951
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 1952 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2011
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 2012 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2071
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2072 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2129
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2130 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2174
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2175 --TTLRLQLEETDHQ 2187
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 1934 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 1990
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 1991 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2047
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2048 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2093
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2094 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2147
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2148 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2203
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2204 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2260
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2261 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2308
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2347
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2192 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2251
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2252 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2308
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2309 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2365
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2366 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2414
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2415 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2473
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2474 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2533
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2534 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2593
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2594 ALAHSEE 2600
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 59.3 bits (142), Expect = 1e-08
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 47/486 (9%)
Query: 169 ITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLP 228
I + + + L + + E + SPA + + ++ +E + + Y+
Sbjct: 1303 INAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK 1362
Query: 229 LYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQ 288
E + R E + Q+R E + + LEK+ QL EA Q A EAK +Q
Sbjct: 1363 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1422
Query: 289 KATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
+ + + E A D Q+ K IQ + Q + + I + + +A R+
Sbjct: 1423 RMQEEVVRR--EEAAVDAQQQ-----KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1475
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRA----AKRRETQEATRNKPFLLR 404
R ++E + + R EG +A + RA A++R+ QE ++
Sbjct: 1476 RIEEE-IRVVRLQLEATERQR---GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1531
Query: 405 TANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLAS--LSANTLPVHITDATRKR 462
+ R Q + A+ + + + R+L L L A + A +R
Sbjct: 1532 DESQRKRQAEVELASRVKAE-----AEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1586
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEV-FKAKLKEN 521
V+ ALE ++ E+ E+ K++ K+ L + H ++ ++ +A+ +
Sbjct: 1587 ARQVQVALETAQRSAEA----ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ 1642
Query: 522 RNNDRKRAK-EYKKELEEMKQRIQTRPYL---FEQVA--KDLAKKEAEQWYLDTLKQAGL 575
+ + +RA+ E ++ELE + + L E+VA K LA+ EAE KQ
Sbjct: 1643 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE-------KQKEE 1695
Query: 576 EEDFVRNKGQG-TRAVQEKETKIKDFPRFQETT------KLSIRDPEQGLEGSLEQPASP 628
E R +G+ +AV+++E ++ + ++ +L+ L EQ
Sbjct: 1696 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1755
Query: 629 RKVLEE 634
R++LEE
Sbjct: 1756 RQLLEE 1761
Score = 54.3 bits (129), Expect = 3e-07
Identities = 103/458 (22%), Positives = 180/458 (39%), Gaps = 48/458 (10%)
Query: 196 EQERQRAQRQGEEEAECHRQF---RAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELL 252
E++RQ A+ ++ ++ RA+ L +E + R + A QKR+EL
Sbjct: 1722 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL- 1780
Query: 253 LSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
+ E K A L A+ + ++T K LE G + AE
Sbjct: 1781 -----------EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE 1829
Query: 313 FRKIR-IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPV 371
++R + A Q+A A Q A R EKL + R +
Sbjct: 1830 AARLRALAEEAKRQRQLAEEDAAR-------QRAEAERVLAEKLAAIGEATRLKTEAEIA 1882
Query: 372 VPDYEGLYKAFQRRA-----AKRRETQEATRNKPFL------LRTAN---LRHPQRPCDA 417
+ + E + +R A +RR ++A ++K + LR A+ L + +
Sbjct: 1883 LKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVED 1942
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLA--SLSANTLPVHITDATRKRESAVRSALEKKNK 475
RRQ + A ++ +G A L + + D R +E A A ++
Sbjct: 1943 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQL 2002
Query: 476 ADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHK-SLEEV--FKAKLKENRNNDRKRAKEY 532
A E + R+ + + KS+ +A K +LEEV KAK++E R + +E
Sbjct: 2003 AAEEER---RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2059
Query: 533 KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT-RAVQ 591
++L+ ++ Q R E+ A A ++ EQ TL+Q D +R + + RA +
Sbjct: 2060 ARQLQLAQEAAQKR-LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2118
Query: 592 EKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPR 629
E E R ++ + + E+ L+ S E+ A R
Sbjct: 2119 EAEEARVQAEREAAQSRRQVEEAER-LKQSAEEQAQAR 2155
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/495 (22%), Positives = 192/495 (38%), Gaps = 78/495 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+E R QR+ + ++ A+ + + R+E ++ +K K+ L +
Sbjct: 1760 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1819
Query: 256 LKPFSFLEKEEQ-----LKEAARQRDLA--------ATAEAKISKQ-----KATRRIPKS 297
F L +E +EA RQR LA A AE ++++ +ATR K+
Sbjct: 1820 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL--KT 1877
Query: 298 ILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQE 353
E AL +K E E R++ Q R L+ + A+ A R + + +
Sbjct: 1878 EAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELER 1935
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ----EATRNKPFLLRTANLR 409
+ G + R + +V + L +F++ AA + E + N LR+
Sbjct: 1936 QKGLVEDTLRQRRQVEEEIL---ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA 1992
Query: 410 H----PQRPCDAATTGRRQDSPQPPATPLPRSRSLSG---LASLSANTLPVHITDATRKR 462
QR A RR+++ + L + A L + +A R R
Sbjct: 1993 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2052
Query: 463 ESA----------VRSALEKKNKADESIQWLEIHRKKS-------QAMSKSVTLRAKAMD 505
E A + A +K+ +A+E + +K+ Q S LR +A
Sbjct: 2053 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2112
Query: 506 PHKSLEEVFKAKLKENRN--NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE 563
++ EE +A+++ R R++ +E ++ + +++ Q R Q A + +KEAE
Sbjct: 2113 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQA--QAAAEKLRKEAE 2170
Query: 564 QWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
Q + ++A E+ +R K Q A EK K F E T EQ L
Sbjct: 2171 Q---EAARRAQAEQAALRQK-QAADAEMEKHKK------FAEQTLRQKAQVEQEL----- 2215
Query: 624 QPASPRKVLEELSHQ 638
+ R LEE HQ
Sbjct: 2216 --TTLRLQLEETDHQ 2228
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/459 (19%), Positives = 185/459 (40%), Gaps = 53/459 (11%)
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
LG S ++ R++ Q E EA RQ A+ +E +++S A + ++R
Sbjct: 1975 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA---EERVQKSLAAEEEAARQR 2031
Query: 249 KELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQ 308
K L + + +E+ +L+E A Q + + +++++ A +R+ A + +
Sbjct: 2032 KAALEEVERLKAKVEEARRLRERAEQE---SARQLQLAQEAAQKRLQAEEKAHAFAVQQK 2088
Query: 309 EAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRV 368
E EL + ++ + LD L+ A ++ RA + A R Q E R +
Sbjct: 2089 EQELQQTLQQEQSVLDQLRGE----AEAARRAAEEAEEA-RVQAE---------REAAQS 2134
Query: 369 NPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQ 428
V + E L ++ + +A R + Q A LR + R A RQ Q
Sbjct: 2135 RRQVEEAERLKQSAEEQAQARAQAQAAAEK----LRKEAEQEAARRAQAEQAALRQK--Q 2188
Query: 429 PPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWL----- 483
+ + + + + +T + E +KN DE +Q L
Sbjct: 2189 AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH----QKNLLDEELQRLKAEAT 2244
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHK---SLEEVFKAKLKENRNNDRKRAKEYKKELEEMK 540
E R++SQ + ++R + + K +E +A + +++N ++ +E E E+MK
Sbjct: 2245 EAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQE---EAEKMK 2301
Query: 541 QRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF 600
Q VA++ A+ L+Q EED + + + ++EK +++
Sbjct: 2302 Q-----------VAEEAARLSVAAQEAARLRQLA-EEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 601 PRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQS 639
R + +L + E E + ++ ++L+ ++
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2388
Score = 40.4 bits (93), Expect = 0.005
Identities = 75/427 (17%), Positives = 177/427 (41%), Gaps = 24/427 (5%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
++E QR + + E A Q + V + ++ R EA +A I + K+
Sbjct: 2233 DEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2292
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP--KSILEPALGDKLQEAELF 313
L+ + EK +Q+ E A + +AA A++ +Q A + +++ E L +K+Q +
Sbjct: 2293 LQEEA--EKMKQVAEEAARLSVAAQEAARL-RQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP-QPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+++ + ++LQ + R + + A + +E GF T + R +
Sbjct: 2350 TRLKAEA---ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2406
Query: 373 PDYEGL-YKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPA 431
+ E L + + A+ R ++A R + H R + + Q
Sbjct: 2407 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH-----------RTELATQEKV 2455
Query: 432 TPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA--LEKKNKADESIQWLEIHRKK 489
T + + A L I + R++E + A L+ K++ +++Q ++ ++
Sbjct: 2456 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQE 2514
Query: 490 SQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYL 549
+QA+ +S ++ + E KAKL++ ++ +A++ ++E + +Q+++
Sbjct: 2515 TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQR 2574
Query: 550 FEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL 609
++ +++ E KQ L++ + + Q +E + + +E +
Sbjct: 2575 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2634
Query: 610 SIRDPEQ 616
++ E+
Sbjct: 2635 ALAHSEE 2641
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 51.6 bits (122), Expect = 2e-06
Identities = 113/564 (20%), Positives = 213/564 (37%), Gaps = 70/564 (12%)
Query: 54 EEEMDSTSDSTGSIYQNLQELKQKGRWCLL----ESLFQSDPESDENLSEDEEDLESFFQ 109
EE+ + ++Q +E + + R +L E L + +P+ L E+EE L +
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 110 DKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSI 169
+ R Q + Q R RR L R Q + + R
Sbjct: 284 QELRRERQEEEQQQQRL---RREQQLRRKQEEERREQQE---------ERREQQERREQQ 331
Query: 170 TVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPL 229
R ++ + ++ + L E+ Q+ +R+ EEE + R Q + L
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 230 YQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQK 289
Q++ + RR+ +++ ++L + EQ +E Q+ E ++ +++
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 290 ATRR-IPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTAT 348
RR K E ++ + + ++ + + R L++ R Q R
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR--- 508
Query: 349 RTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANL 408
R Q+E R + R+ + E L + + RRE +E R + L R
Sbjct: 509 REQEE---------RREQRLKR-QEEEERLQQRLRSEQQLRREQEE--RREQLLKREEEK 556
Query: 409 RHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRS 468
R Q + R Q+ + R L KRE R
Sbjct: 557 RLEQERREQRLK-REQEERRDQLLKREEERRQQRL-----------------KREQEER- 597
Query: 469 ALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKR 528
LE++ K +E ++ LE ++ Q + + + KS E+ + + + R +R
Sbjct: 598 -LEQRLKREE-VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 529 AKEYKKELEE--MKQRIQTRPYLFEQVAKDLAKKEAE-------------QWYLDTLKQA 573
+ K+E EE ++QR++ R + E+ ++LA++E E QW L++ A
Sbjct: 656 EQRLKREEEEERLEQRLK-REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 574 GLEEDFVR-NKGQGTRAVQEKETK 596
+ + R K +G R QE+E K
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEK 738
Score = 47.8 bits (112), Expect = 3e-05
Identities = 95/461 (20%), Positives = 187/461 (40%), Gaps = 57/461 (12%)
Query: 176 RMTLREARKKAEWLGSPASFEQERQRAQRQG--------EEEAECHRQFRAQPVPAHVYL 227
R E R++ E P E+E++R QR+ EEE + R+ RAQ +
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE--- 852
Query: 228 PLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISK 287
++ ++ + RR++ Q+R + + QL+E ++R T AK +
Sbjct: 853 ---EDGLQEDQERRRSQEQRRDQ------------KWRWQLEEERKRR--RHTLYAKPAL 895
Query: 288 QKATRRIPKSILEPALGDKLQEAELFRKIR----IQMRALDMLQMASSPIASSSNRANPQ 343
Q+ R+ + + E ++LQ E ++ R Q R + LQ +
Sbjct: 896 QEQLRKEQQLLQEEE--EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE---- 949
Query: 344 PRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLL 403
R +QE+ + + Q + ++ + E + Q R K RE +E + + LL
Sbjct: 950 ----KRRRQERERQYRKDKKLQQKEEQLLGE-EPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 404 RTANLRHPQRPCDAATTGRRQDSPQPPATPLPR----SRSLSGLASLSANTLPVHITDAT 459
R R +R + R++D Q L R R L + +
Sbjct: 1005 REE--REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 460 ---RKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKA 516
+RE+ R LE++ + +E +Q E + + + R + + L++ +
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Query: 517 KLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLE 576
L+E R +++R +E +++ E ++ Q L + + ++E E+ Y + + E
Sbjct: 1123 LLREER--EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 577 EDFVRNKGQGTRAVQEKETKIKDFPRFQ-ETTKLSIRDPEQ 616
E +R + + R QE+E + ++ Q + K RD +Q
Sbjct: 1181 EQLLREEQEKRR--QERERQYREEEELQRQKRKQRYRDEDQ 1219
Score = 46.6 bits (109), Expect = 7e-05
Identities = 101/479 (21%), Positives = 181/479 (37%), Gaps = 75/479 (15%)
Query: 180 REARKKAEWLGSPASFEQ-ERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSE 238
RE ++ +WL E+ E++R ++Q + + E R+ R +L L +E ER E
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER--------WLKLEEE--ERRE 498
Query: 239 ARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRR--IPK 296
+ + Q R+E + E+EE+L++ R +E ++ +++ RR + K
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLR-------SEQQLRREQEERREQLLK 551
Query: 297 SILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLG 356
E L + +E L R+ Q D L + + R R ++E++
Sbjct: 552 REEEKRLEQERREQRLKRE---QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 357 FLHTNFRFQPRVNPVVPDYEGLYKAF------QRRAAKRRETQEATRNKPFLLRTANLRH 410
L R + R+ P+ E + +RR + R Q+ R + R
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668
Query: 411 PQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLS------ANTLPVHITDATRKRES 464
QR RR+ R R S + A+ + RK+E
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 465 AVR--SALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENR 522
R EK+ + + +QW E R H+ +E E +
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERA------------------HRQQQE-------EEQ 763
Query: 523 NNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRN 582
D + +++ E +QR+ RP L EQ + L +E +Q +Q L E+ +
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPEEEEKE 818
Query: 583 KGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGL---EGSLEQPASPRKVLEELSHQ 638
+ + R +EKE + +E +L R+ Q L E L++ R+ E+ Q
Sbjct: 819 QRRRQRREREKELQF-----LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Score = 42.4 bits (98), Expect = 0.001
Identities = 94/472 (19%), Positives = 182/472 (38%), Gaps = 76/472 (16%)
Query: 197 QERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMER-----SEARRQAGIQKRKEL 251
+E +R Q EEE E R+ +P + L E R S R+Q G ++R+E
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQW-QLESEADARQSKVYSRPRKQEGQRRRQEQ 735
Query: 252 LLSSLKPFSFLEKEE------QLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGD 305
+ S L+ +E Q +E ++RD +A+ ++ +R+ P L +
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA---RPPLRE 792
Query: 306 KLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQ 365
+ + Q+RA + Q + + Q R R ++++L FL + Q
Sbjct: 793 QRER---------QLRAEERQQREQRFLPEEEEKE--QRRRQRREREKELQFLEEEEQLQ 841
Query: 366 --PRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQR------PCDA 417
R + + +GL + +RR +QE R++ + + R +R P
Sbjct: 842 RRERAQQLQEEEDGL-----QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 418 ATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKAD 477
+ Q Q L R R+R+ R E++
Sbjct: 897 EQLRKEQQLLQEEEEELQREER------------------EKRRRQEQERQYREEEQLQQ 938
Query: 478 ESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYK-KEL 536
E Q L R+K + R + K L++ + L E R++ +E K +E
Sbjct: 939 EEEQLLREEREKRRRQE-----RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 537 EEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGL--EEDFVRNKGQGTRAVQEKE 594
EE++Q + + + ++ K+ ++W K+ L EE+ + + + R +QE+E
Sbjct: 994 EELQQEEE------QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Query: 595 TKIKDFPRFQETTKLSIRDP-----EQGLEGSLEQPASPRKVLEELSHQSPE 641
+ ++ Q+ + + + Q LE + ++ E+L + PE
Sbjct: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099
Score = 42.4 bits (98), Expect = 0.001
Identities = 96/481 (19%), Positives = 173/481 (35%), Gaps = 71/481 (14%)
Query: 179 LREARKKAEWLGSPASFEQERQRAQRQGE------EEAECHRQFRAQPVPAHVYLPLYQE 232
+R ++ ++L QER R R+ E EE + HRQ R +
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF----------- 1487
Query: 233 IMERSEARRQAGIQKRKELLLSSLKPF-SFLEKEEQLKEAARQRDLAATAEAKISKQKAT 291
+ E + RRQ +K +E L S +P FLE+E+QL RQR + +++
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 292 RRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQ 351
+R K +E E R+ R + + + + R Q R +
Sbjct: 1548 QR------RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 352 QEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQ--EATRNKPFLLRTANLR 409
Q+ R Q + + + ++ ++ +R E Q R++ FL LR
Sbjct: 1602 QQ--------LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 410 HPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSA 469
+R R D R R L ++ E
Sbjct: 1654 RQEREQQL-----RHD----------RDRKFREEEQL------------LQEGEEQQLRR 1686
Query: 470 LEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRA 529
E+ K E Q L ++ + + + LR + ++ EE + +E +R
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR---QETEQEQLRRQ 1743
Query: 530 KEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRA 589
+ Y+K LEE + R + + +D +E EQ + +Q ++ R + +
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL 1803
Query: 590 VQEKE-----TKIKDFPRFQETTKLSIRDPEQGL--EGSLEQPASPRKVLEELSHQSPEN 642
QE+E + +D E +L + + EQ L E + A + +E S + +
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Query: 643 L 643
L
Sbjct: 1864 L 1864
Score = 40.8 bits (94), Expect = 0.004
Identities = 90/474 (18%), Positives = 191/474 (40%), Gaps = 85/474 (17%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSS 255
E+ER++ + + E+E ++ + + V L QE +R+ ++R++ LL S
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVER-----LEQEERREQRLKREEPEEERRQQLLKS 636
Query: 256 LKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSIL--------EPALGDKL 307
E++E+ ++ +R+ E ++ +++ R+ + + E L ++
Sbjct: 637 -------EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 308 QEAELFR-KIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQP 366
QE R K RI + A + + +R Q R +QE+ + +
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE--------KRRR 741
Query: 367 RVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDS 426
R + + +Q R+ QE + + F + +R GR++ S
Sbjct: 742 RESEL---------QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER-------GRQRLS 785
Query: 427 PQPPATPLPRSRSLSG--LASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLE 484
+PP R R L LP R+R+ R + + +E +Q
Sbjct: 786 ARPPLRE-QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ--- 841
Query: 485 IHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQR-- 542
R+++Q + + E+ + + R+ +++R ++++ +LEE ++R
Sbjct: 842 -RRERAQQLQEE--------------EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 543 --IQTRPYLFEQVAKD--LAKKEAEQWYLDTL---------KQAGLEEDFVRNKGQGTRA 589
+ +P L EQ+ K+ L ++E E+ + +Q EE + + Q R
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 590 VQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENL 643
+EK + + ++++ KL + E+ L G E+P R+ E ++ E L
Sbjct: 947 EREKRRRQERERQYRKDKKL--QQKEEQLLG--EEPEKRRRQEREKKYREEEEL 996
Score = 38.5 bits (88), Expect = 0.019
Identities = 95/464 (20%), Positives = 181/464 (39%), Gaps = 72/464 (15%)
Query: 196 EQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQK--RKELLL 253
E++ R +R+ E RQ+R + V Q + E E RR+ +++ R+E L
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEE---EVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176
Query: 254 SSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIP------KSILEPALGDKL 307
+ L +E++ + R+R E + K+K R K EP + +
Sbjct: 1177 QQEEE-QLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 308 QEAELFRKIRI--QMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQ 365
++ +++ K R Q R L+ Q+ + + R Q+ + R+Q
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR--------RWQ 1287
Query: 366 PRVNPVVPDYEGLYKAFQRRAAKR-RETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQ 424
R + P+ E L + Q+ A +R R++QE K L + ++ D Q
Sbjct: 1288 QR-DRHFPEEEQLEREEQKEAKRRDRKSQE---EKQLLREEREEKRRRQETDRKFREEEQ 1343
Query: 425 DSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRK-RESAVRSALEKKNKADESIQWL 483
+ PL R + RK RE +R E+ K E Q L
Sbjct: 1344 LLQEREEQPLRRQ-------------------ERDRKFREEELRHQ-EQGRKFLEEEQRL 1383
Query: 484 EIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKE-------- 535
++ + + + LR + + + K + +E + + ++R +++++E
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 536 -----LEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAV 590
LEE +Q Q R F + + L ++E +Q + + LEE+ + + R
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF 1503
Query: 591 QEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEE 634
+E+E R QE + + + +Q L + RK L+E
Sbjct: 1504 REQEL------RSQEPERKFLEEEQQ-----LHRQQRQRKFLQE 1536
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 47.4 bits (111), Expect = 4e-05
Identities = 81/396 (20%), Positives = 145/396 (36%), Gaps = 42/396 (10%)
Query: 109 QDKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNI-PRPQTQPPSGSRPPSQHRSVSSWAS 167
Q + ++ P L G + + + P I P Q PS +P SQ + SS +
Sbjct: 2344 QSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQT 2403
Query: 168 --------SITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQ 219
+TV P R L+ + + + + P +Q + +Q Q + A+ Q
Sbjct: 2404 LSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGV 2463
Query: 220 PVPAHVYLPLY------------QEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQ 267
P + LP+ Q ++ A Q +Q+ ++L K K++Q
Sbjct: 2464 PQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQK------KKQQ 2517
Query: 268 LKEAARQRDLAATAEAKISKQKATRRI--------PKSILEPALGDKLQEAELFRKIRIQ 319
E R+ L A+ +++I +++ + K + PA ++ Q + ++
Sbjct: 2518 QIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKY 2577
Query: 320 MRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLY 379
+ LD + A R + ++ KL L + Q R ++ L
Sbjct: 2578 I--LDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAE-ILKKRALLD 2634
Query: 380 KAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRS 439
K Q + + + + L++ A PC T PP+ P P +
Sbjct: 2635 KDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQ 2694
Query: 440 LSGLASLSANTLPVHITDATRKRESAVRSALEKKNK 475
+GL LS TLP RKRE S+ + K K
Sbjct: 2695 HTGL--LSTPTLPA--ASQKRKREEEKDSSSKSKKK 2726
Score = 35.4 bits (80), Expect = 0.16
Identities = 86/419 (20%), Positives = 156/419 (37%), Gaps = 47/419 (11%)
Query: 139 PSNIPRPQTQPPSGSRPPSQHRSVSSWASSIT--VPRPFRMTLREARKKAEWLGSPASFE 196
PS P+PQTQP S ++P Q + ++++ VP + T ++ K A+
Sbjct: 2275 PSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKP-----QVAAQS 2329
Query: 197 QERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSL 256
Q + Q Q + Q R +P P Q+ ++ + IQ L + S
Sbjct: 2330 QPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSP-GQQSQVQTTTSQPIPIQPHTSLQIPSQ 2388
Query: 257 -KPFS--FLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAELF 313
+P S ++ Q + + + + + + + P+ I P L ++Q
Sbjct: 2389 GQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLS-- 2446
Query: 314 RKIRIQMRALDMLQMASSPIASSSNRANP---QPRTATRTQQEKLGFLHTNFRFQPRVNP 370
+IQ + + +Q S + P Q +A +T Q + Q ++
Sbjct: 2447 ---QIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQR 2503
Query: 371 VVPDYEGLYKAFQRR-AAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQP 429
V + K Q++ KR T +A+ + + ++H +A +Q
Sbjct: 2504 VQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKH-----NAVIEHLKQKKSMT 2558
Query: 430 PATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLEIHRKK 489
PA R + N + +I D K E KK K +ES+ E R K
Sbjct: 2559 PAEREENQR------MIVCNQVMKYILDKIDKEEKQA----AKKRKREESV---EQKRSK 2605
Query: 490 SQAMSKSV-------TLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQ 541
A S LRA+ + L++ + +++E D K KE K+L ++ Q
Sbjct: 2606 QNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKE--KDLMQLAQ 2662
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 46.2 bits (108), Expect = 9e-05
Identities = 113/541 (20%), Positives = 203/541 (37%), Gaps = 85/541 (15%)
Query: 128 STRRCS-SLNNLPSNIPRPQTQPPSGS-----RPPSQHRSV--SSWASSI---------- 169
S RCS S NLP ++ + S S PS++RS+ S+W SSI
Sbjct: 247 SGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLMTPTLS 306
Query: 170 ---------TVPRPFRMTLR--EARKKAEWLGSPASFEQERQRAQRQGEEEAE-CHRQFR 217
T+PR R R + + W + AS + Q + C R
Sbjct: 307 FLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSAS 366
Query: 218 AQPV-PAHVYLPLYQ--EIMERSEARRQ------AGIQKRKELLLSSLKPFSFLEKEEQL 268
A P+ P V +++ ER E R+ A +++R E P EK+++
Sbjct: 367 ASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEA-----SPVQKKEKKDKE 421
Query: 269 KEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQM 328
+E +++ A E + K+++ P++ L + +L K R + +
Sbjct: 422 RENEKEKS-ALARERSLKKRQSLPASPRARLSASTASELSPKS---KARPSSPSTSWHRP 477
Query: 329 ASS-PIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAA 387
AS P + P+P + T G + + + P+ + K RRA+
Sbjct: 478 ASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSK---RRAS 534
Query: 388 KRRETQEATRNKPFLLRTANLRHPQR---PCDAATTGRRQDSPQPPATPLPRSRSLSGLA 444
+E+ P + PQ+ P + T SP PA P+ S+ ++G
Sbjct: 535 NEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAG-- 592
Query: 445 SLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAM 504
T RE A R EK+ +A E + E R+ K + A
Sbjct: 593 --------------TTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAR 638
Query: 505 DPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQ 564
+ E +A+ +E + A+E + +E ++R+Q + ++ A+ +++EAE+
Sbjct: 639 EAEARAEREAEARRREEQE-----AREKAQAEQEEQERLQKQ----KEEAEARSREEAER 689
Query: 565 WYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQ 624
L+ K +E + + + + ++ K + TK E GS +
Sbjct: 690 QRLEREKHFQQQEQERQERRKRLEEIMKRTRKSE-----VSETKQKQDSKEANANGSSPE 744
Query: 625 P 625
P
Sbjct: 745 P 745
Score = 36.6 bits (83), Expect = 0.074
Identities = 45/217 (20%), Positives = 91/217 (41%), Gaps = 7/217 (3%)
Query: 139 PSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQE 198
PS P P PP +PP++ + ++ +S P P + + + ++
Sbjct: 547 PSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEK 606
Query: 199 RQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKP 258
R++A+ Q E E E R+ +A+ L +E R+E R+A ++R+E +
Sbjct: 607 RRQAREQRERE-EQERRLQAERDKRMREEQLAREAEARAE--REAEARRREE---QEARE 660
Query: 259 FSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAELFRKIRI 318
+ E+EEQ + ++ + A + + +Q+ R E ++ + E K
Sbjct: 661 KAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTR 720
Query: 319 QMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKL 355
+ + Q S A ++N ++P+P A + L
Sbjct: 721 KSEVSETKQKQDSKEA-NANGSSPEPVKAVEARSPGL 756
Score = 29.6 bits (65), Expect = 9.0
Identities = 37/147 (25%), Positives = 60/147 (40%), Gaps = 34/147 (23%)
Query: 143 PRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRA 202
P P P +RPP + SS S VP ++ KKA ER +
Sbjct: 96 PTPPAMGPRDARPPRR----SSQPSPTAVPASDSPPTKQEVKKA----------GERHKL 141
Query: 203 QRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFL 262
++ EE RA+ + A + L +E E+++A R+ +Q+R+ L
Sbjct: 142 AKERREE-------RAKYLAAKKAVWLEKE--EKAKALREKQLQERRRRL---------- 182
Query: 263 EKEEQLKEAARQRDLAATAEAKISKQK 289
+E++LK R+ L K+ K K
Sbjct: 183 -EEQRLKAEQRRAALEERQRQKLEKNK 208
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/186 (25%), Positives = 90/186 (48%), Gaps = 21/186 (11%)
Query: 457 DATRKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKA 516
D RK E R +E++ KA + + S M K T+ + + P K LE F+
Sbjct: 324 DEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYK--TISQEFLTPGK-LEINFEE 380
Query: 517 KLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLE 576
LK+ +++R +E +K EM+++ FEQ+ +++ ++E E +T +
Sbjct: 381 LLKQKMEEEKRRTEEERKHKLEMEKQ------EFEQLRQEMGEEEEEN---ETFGLSREY 431
Query: 577 EDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELS 636
E+ ++ K G ++Q K K K F++ +LS ++ ++ +E E+ A R + E+
Sbjct: 432 EELIKLKRSG--SIQAKNLKSK----FEKIGQLSEKEIQKKIE---EERARRRAIDLEIK 482
Query: 637 HQSPEN 642
+ EN
Sbjct: 483 EREAEN 488
Score = 31.6 bits (70), Expect = 2.4
Identities = 50/225 (22%), Positives = 89/225 (39%), Gaps = 47/225 (20%)
Query: 460 RKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLK 519
R+ + RS EK+ + ++ I+ E +R+K + K + D +E+ + KL
Sbjct: 42 REERNQRRSRDEKQRRKEQYIREREWNRRKQEI--KEMLASDDEEDVSSKVEKAYVPKLT 99
Query: 520 ENRNN-----DRKRAKEYKKELEE-MKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQA 573
+++R +E +K EE K+RI+ ++ ++LAK+ AEQ ++ +
Sbjct: 100 GTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKR-AEQ--IEDINNT 156
Query: 574 GLE------------------------------EDFVRNKGQGTRAVQEKETKIK---DF 600
G E ED + + + R E++ +I+
Sbjct: 157 GTESASEEGDDSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQR 216
Query: 601 PRFQETTKLS-IRDPEQGLEGSLE--QPASPRKVLEELSHQSPEN 642
P +E LS + D E E E P + EEL Q EN
Sbjct: 217 PSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQEN 261
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 43.5 bits (101), Expect = 6e-04
Identities = 56/222 (25%), Positives = 89/222 (40%), Gaps = 24/222 (10%)
Query: 381 AFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSP---QPPATPLPRS 437
A+ R R E R++ + A+ P +P T RR S +P +P PR
Sbjct: 98 AYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRI 157
Query: 438 RSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSV 497
S T+ H KR+ S ++ K+DESI+ + K + V
Sbjct: 158 TR----KSTRQTTITSHFAKGPAKRKPQEES---ERAKSDESIKEED---KDQDEKRRRV 207
Query: 498 TLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDL 557
T R + P + EE +AK + R +E + E EE + R QT+ +Q K+
Sbjct: 208 TSRERVARPLPA-EEPERAK-----SGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEE 261
Query: 558 AKKEAEQWYLDTLKQAGLEEDFVRNKGQ-----GTRAVQEKE 594
+EA + G E+D +++ Q R +EKE
Sbjct: 262 PDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKE 303
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 43.5 bits (101), Expect = 6e-04
Identities = 101/503 (20%), Positives = 202/503 (40%), Gaps = 75/503 (14%)
Query: 185 KAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAG 244
+A+ L AS EQ Q Q+Q + + + RA + L + +EI+ + +
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDL--ELRATELSKQ--LEMEKEIVSST----RLD 787
Query: 245 IQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALG 304
+QK+ E L S + L K+E+ K+ +Q + E KI ++ RI ++ E
Sbjct: 788 LQKKSEALESIKQK---LTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE---- 840
Query: 305 DKLQEAELFRKIRIQMRAL--------DMLQMASSPIASSSN---RANPQPRTATRTQQE 353
+K++++ AL D L S + +S + + N + + A ++
Sbjct: 841 --------LQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Query: 354 KLGFLHTNFRFQPRVNPVVPDYEGLYKAFQR-RAAKRRETQEATRNKPFLLRTANLRHPQ 412
L + Q ++ + + + L K+ ++ + A + E + L++ N
Sbjct: 893 TCKEL--KHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN 950
Query: 413 RPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEK 472
+ G + Q + +L G ++ + T+ K + + A ++
Sbjct: 951 EKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAV----LQKTELENKLQQQLTQAAQE 1006
Query: 473 KNKADESIQWLEIHRKKSQAMSKSVT---------LRAKAMDPHKSLEE---VFKAKLKE 520
E I L+ + +KSQ K + L A D KS+EE + + L
Sbjct: 1007 LAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDL-KSVEEKLSLAQEDLIS 1065
Query: 521 NRN---NDRKRAKEYK-------KELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTL 570
NRN N K +E K ++ + +Q++Q R + + K+ + KE E +
Sbjct: 1066 NRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKEL-VNEKS 1124
Query: 571 KQAGLEEDFVRNKGQGTRAVQEKE----------TKIKDFPRFQETTKLSIRDPEQGLEG 620
K A +EE R + + T+ +E + T +KD + KL ++ L+
Sbjct: 1125 KLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKA 1184
Query: 621 SLEQPASPRKVLEELSHQSPENL 643
++EQ +++L++ + E L
Sbjct: 1185 AVEQEKRNQQILKDQVKKEEEEL 1207
Score = 30.8 bits (68), Expect = 4.1
Identities = 79/426 (18%), Positives = 170/426 (39%), Gaps = 41/426 (9%)
Query: 191 SPASFEQERQRAQRQGEE-EAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRK 249
S + FE+E Q+ + + E C V L +E+ + E ++A Q +
Sbjct: 872 SKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKL 931
Query: 250 ELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDK--- 306
EL +S++ ++ + LK+ ++ + I++ K + K +E G+
Sbjct: 932 EL--NSMQE-QLIQAQNTLKQNEKEEQ---QLQGNINELKQSSEQKKKQIEALQGELKIA 985
Query: 307 -LQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQ 365
LQ+ EL K++ Q L A+ +A+ + + ++Q+ F F
Sbjct: 986 VLQKTELENKLQQQ------LTQAAQELAAEKEKISVLQNNYEKSQET---FKQLQSDFY 1036
Query: 366 PRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNK----PFLLRTANLRHPQRPCDAATTG 421
R + ++ + L K+ + + + +E + RN+ L++ D+A
Sbjct: 1037 GRESELLATRQDL-KSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKE 1095
Query: 422 RRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALE--KKNKADES 479
++ + + +SL ++ + I + ++E + E K +K +
Sbjct: 1096 QQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESI 1155
Query: 480 IQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEM 539
+ + K + + + L+ KA + KA +++ + N + + KKE EE+
Sbjct: 1156 KEITNLKDAKQLLIQQKLELQGKA--------DSLKAAVEQEKRNQQILKDQVKKEEEEL 1207
Query: 540 KQR-IQTRPYLFEQVAKDLA--KKEAEQWYLDTLKQAGLEEDF--VRNKGQGT-RAVQEK 593
K+ I+ L ++ + KK E T++ L E+ V+ + Q + R V E
Sbjct: 1208 KKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSEL 1267
Query: 594 ETKIKD 599
E + D
Sbjct: 1268 EKQTDD 1273
Score = 30.4 bits (67), Expect = 5.3
Identities = 37/198 (18%), Positives = 91/198 (45%), Gaps = 20/198 (10%)
Query: 461 KRESAVRSALEKKNK-ADESIQWLEIHRKKSQAMSKSVTLRA---KAMDPHK---SLEEV 513
+R+ + ++K+ + AD ++ + + + ++ S L+ K H+ +L++
Sbjct: 440 QRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQS 499
Query: 514 FKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQA 573
AKL+E +N+ ++ +++ + Q+IQ L ++ ++++ E E+ L QA
Sbjct: 500 TTAKLREAQND----LEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQA 555
Query: 574 GLEEDFVRN---------KGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQ 624
G E V N + Q T+ ++ + + + + QE +++ + L + ++
Sbjct: 556 GEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDR 615
Query: 625 PASPRKVLEELSHQSPEN 642
S + EL+ Q E+
Sbjct: 616 VLSLETSVNELNSQLNES 633
Score = 30.0 bits (66), Expect = 6.9
Identities = 30/165 (18%), Positives = 67/165 (40%), Gaps = 7/165 (4%)
Query: 455 ITDATRKRESAVRSALEKKN---KADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLE 511
+ + T+K ++ + L+K+ K +E + +K QA L + + S
Sbjct: 297 VNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS 356
Query: 512 EVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE----QWYL 567
E ++ + + ++ K+EL E++ + Q F+Q+ + +KE Q +
Sbjct: 357 ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEI 416
Query: 568 DTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIR 612
+ L LE + + G Q + + K + Q+ L ++
Sbjct: 417 NQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLK 461
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/157 (20%), Positives = 72/157 (45%), Gaps = 4/157 (2%)
Query: 460 RKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLK 519
R E + EK + DE + LE + + R K + K LE+ + + +
Sbjct: 472 RMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE---REKEREREKELEKEQEQERE 528
Query: 520 ENRNNDRKRAKEYKKELE-EMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEED 578
+ R DR+R +E +KELE E +++ + ++ K+L +++ ++ L +K+ E +
Sbjct: 529 KEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECE 588
Query: 579 FVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPE 615
+ + + ++ +E ++ QE+ ++ E
Sbjct: 589 LEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
Score = 38.1 bits (87), Expect = 0.025
Identities = 43/190 (22%), Positives = 84/190 (44%), Gaps = 28/190 (14%)
Query: 472 KKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKA----KLK-------- 519
K+ ADE W + R++S+ + R + + + +EE KA KLK
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
Query: 520 ------------ENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQ-VAKDLAKKEAEQWY 566
R +R+R KE +KE E+ +++ + + +Q K+L K++ +Q
Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
Query: 567 LDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKL--SIRDPEQGLEGSLEQ 624
++ ++ E++ R K + + +Q+ + + K+ +E KL I E LE +E+
Sbjct: 555 MEKERKQEKEKELERQK-EKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK 613
Query: 625 PASPRKVLEE 634
S +E
Sbjct: 614 QESENSCNKE 623
Score = 36.6 bits (83), Expect = 0.074
Identities = 40/190 (21%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 69 QNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQCPQALRCGS 128
+ LQ++K++ + C LE + + +E + E +LE + ++ + C +
Sbjct: 575 KELQKMKEQEKECELE---KEREKLEEKIEPREPNLEPMVEKQES---ENSCNKEEEPVF 628
Query: 129 TRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEW 188
TR+ S+ + + +T+P SGS+P + +S + P R ++ + K
Sbjct: 629 TRQDSNRSEKEATPVVHETEPESGSQP--RPAVLSGYFKQFQKSLPPRFQRQQEQMK--- 683
Query: 189 LGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKR 248
+Q+ Q+ Q+QG Q + VP + PLYQ + + G R
Sbjct: 684 -------QQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPR 736
Query: 249 KELLLSSLKP 258
++ S + P
Sbjct: 737 WLMMQSYMDP 746
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/222 (21%), Positives = 98/222 (44%), Gaps = 25/222 (11%)
Query: 416 DAATTGRRQDSPQPPATP-------LPRSRSLSGLASLSANTL-------PVHITDATRK 461
D A +G+ P PP P R RS SG++ +S+ ++ PV + D ++
Sbjct: 287 DVAMSGQ----PLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPV-LEDEQQQ 341
Query: 462 RESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKEN 521
E + E K + + LE+ +++ + + + + ++ +E K +E
Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQE---RKERER 398
Query: 522 RNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVR 581
+ +RKR E +K+LE+ ++ + R E+ K++ ++EA + L+ +Q E + +
Sbjct: 399 QEQERKRQLELEKQLEKQRELERQRE---EERRKEIERREAAKRELERQRQLEWERNRRQ 455
Query: 582 NKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
QE +K + E ++ D + LEG L+
Sbjct: 456 ELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQ 497
Score = 33.1 bits (74), Expect = 0.82
Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 18/136 (13%)
Query: 179 LREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSE 238
L + RK+ E L EQER+ +RQ E E RQ L L +++ ++ E
Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQ---EQERKRQ-----------LELEKQLEKQRE 418
Query: 239 ARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSI 298
RQ ++RKE+ LE++ QL+ +R K + + K
Sbjct: 419 LERQREEERRKEIERREAAKRE-LERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKT 477
Query: 299 LE---PALGDKLQEAE 311
LE AL DK + E
Sbjct: 478 LEFELEALNDKKHQLE 493
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/222 (21%), Positives = 98/222 (44%), Gaps = 25/222 (11%)
Query: 416 DAATTGRRQDSPQPPATP-------LPRSRSLSGLASLSANTL-------PVHITDATRK 461
D A +G+ P PP P R RS SG++ +S+ ++ PV + D ++
Sbjct: 287 DVAMSGQ----PLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPV-LEDEQQQ 341
Query: 462 RESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKEN 521
E + E K + + LE+ +++ + + + + ++ +E K +E
Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQE---RKERER 398
Query: 522 RNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVR 581
+ +RKR E +K+LE+ ++ + R E+ K++ ++EA + L+ +Q E + +
Sbjct: 399 QEQERKRQLELEKQLEKQRELERQRE---EERRKEIERREAAKRELERQRQLEWERNRRQ 455
Query: 582 NKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLE 623
QE +K + E ++ D + LEG L+
Sbjct: 456 ELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQ 497
Score = 33.1 bits (74), Expect = 0.82
Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 18/136 (13%)
Query: 179 LREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSE 238
L + RK+ E L EQER+ +RQ E E RQ L L +++ ++ E
Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQ---EQERKRQ-----------LELEKQLEKQRE 418
Query: 239 ARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSI 298
RQ ++RKE+ LE++ QL+ +R K + + K
Sbjct: 419 LERQREEERRKEIERREAAKRE-LERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKT 477
Query: 299 LE---PALGDKLQEAE 311
LE AL DK + E
Sbjct: 478 LEFELEALNDKKHQLE 493
>gi|32484977 angiomotin like 2 [Homo sapiens]
Length = 780
Score = 41.6 bits (96), Expect = 0.002
Identities = 83/410 (20%), Positives = 154/410 (37%), Gaps = 57/410 (13%)
Query: 197 QERQRAQRQGEEEAECHRQ-FRAQPVPAH-VYLPLYQEIMERSE--ARRQAGIQ------ 246
QE Q + QG E +R P P+ LP Y+E S+ A +QAG +
Sbjct: 72 QEPQGQEHQGGENHLAENTLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGTRPHAGDR 131
Query: 247 ---------KRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKS 297
+R++ L L+ E+L + + +R+ A A + +S + ++ ++
Sbjct: 132 DPRGAPGGSRRQDEALRELRHGHVRSLSERLLQLSLERN-GARAPSHMSSSHSFPQLARN 190
Query: 298 ILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGF 357
P L E R Q + + ++ + RA P F
Sbjct: 191 QQGPPLRGPPAEGPESRGPPPQYPHVVLAHETTTAVTDPRYRARGSPH-----------F 239
Query: 358 LHTNFRF-QPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCD 416
H R Q +V PV + Y+ Q ++QE HP P
Sbjct: 240 QHAEVRILQAQVPPVFLQQQQQYQYLQ-------QSQE---------------HPPPPHP 277
Query: 417 AATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVH--ITDATRKRESAVRSALEKKN 474
AA S PPA P S S S SA+ + + + R + R E ++
Sbjct: 278 AALGHGPLSSLSPPAVEGPVSAQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELES 337
Query: 475 KADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKK 534
A+++ + +E + Q +S++ +A ++LE+ + K+ + ++ ++
Sbjct: 338 SAEKAGR-IEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRE 396
Query: 535 ELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKG 584
LE +R+ ++ + ++D+ K Q Y +Q LE + +G
Sbjct: 397 RLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRG 446
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 41.2 bits (95), Expect = 0.003
Identities = 89/466 (19%), Positives = 169/466 (36%), Gaps = 65/466 (13%)
Query: 197 QERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSL 256
+E Q + EEE E R RA+ +E+ E SE +AG ++ L+
Sbjct: 1110 KELQARIEELEEEIEAERATRAKTEKQRS--DYARELEELSERLEEAGGVTSTQIELNKK 1167
Query: 257 KPFSFLEKEEQLKEAARQRDLAATA----------------------EAKISKQKATRRI 294
+ FL+ L+EA Q + A + K+ K+K+ ++
Sbjct: 1168 REAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 1227
Query: 295 P----KSILEPALGDKLQEAELFRKIRIQMRAL----DMLQMASSPIASSSNRANPQPRT 346
S +E K ++ R + Q+ + +Q + S + + +R +
Sbjct: 1228 EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGE 1287
Query: 347 ATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAF-QRRAAKRRETQEATRNKPFLLRT 405
+R +EK +V +AF Q+ +R+ +E + K L
Sbjct: 1288 LSRQLEEK--------------ESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHA 1333
Query: 406 ANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESA 465
L+ + CD R+ + R+LS S A + TDA ++ E
Sbjct: 1334 --LQSSRHDCDLL----REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEEL 1387
Query: 466 VRSALEKKNKADESIQWLEIHRKKSQAMSKS-VTLRAKAMDPHKSLEEV--FKAKLKENR 522
+ + + +S + +E K ++ K+ L+ + D +E A L + +
Sbjct: 1388 EEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQ 1447
Query: 523 NNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAK-KEAEQWYLDTLKQAGLEE---- 577
N K E+K + EE + ++ ++ +L K K A + LD L+ E
Sbjct: 1448 RNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLE 1507
Query: 578 ----DFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLE 619
D + + + E E K + +L++ + E LE
Sbjct: 1508 QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALE 1553
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 40.0 bits (92), Expect = 0.007
Identities = 43/186 (23%), Positives = 86/186 (46%), Gaps = 16/186 (8%)
Query: 466 VRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNND 525
V+ +++ D++ Q L +K ++++ S K ++ + E +L + +
Sbjct: 162 VKELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQN 221
Query: 526 RKRAKEYKKE---LEEMKQRIQTRPYLFEQVAKDLAKKEAEQ-WYLDTLKQAGLEEDFVR 581
+K ++Y + LE RI+ + ++ L KE+ + LD LKQ E+ R
Sbjct: 222 KKMNRDYTRNASNLERNDLRIE------DGISSTLPSKESRRKGGLDYLKQV---ENETR 272
Query: 582 NKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEE--LSHQS 639
NK + + +++ K+KD + E K I+ E LE L++ S L++ LS Q+
Sbjct: 273 NKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFE-SLEEELKKMKSKNNDLQDNYLSEQN 331
Query: 640 PENLVS 645
L++
Sbjct: 332 KNKLLA 337
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 40.0 bits (92), Expect = 0.007
Identities = 43/186 (23%), Positives = 86/186 (46%), Gaps = 16/186 (8%)
Query: 466 VRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNND 525
V+ +++ D++ Q L +K ++++ S K ++ + E +L + +
Sbjct: 162 VKELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQN 221
Query: 526 RKRAKEYKKE---LEEMKQRIQTRPYLFEQVAKDLAKKEAEQ-WYLDTLKQAGLEEDFVR 581
+K ++Y + LE RI+ + ++ L KE+ + LD LKQ E+ R
Sbjct: 222 KKMNRDYTRNASNLERNDLRIE------DGISSTLPSKESRRKGGLDYLKQV---ENETR 272
Query: 582 NKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEE--LSHQS 639
NK + + +++ K+KD + E K I+ E LE L++ S L++ LS Q+
Sbjct: 273 NKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFE-SLEEELKKMKSKNNDLQDNYLSEQN 331
Query: 640 PENLVS 645
L++
Sbjct: 332 KNKLLA 337
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 40.0 bits (92), Expect = 0.007
Identities = 59/277 (21%), Positives = 108/277 (38%), Gaps = 42/277 (15%)
Query: 142 IPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQR 201
+P+P+ + P RPPS S SS + S V R R+ ++ E ++E R
Sbjct: 284 LPKPRGRKPKPERPPS---SSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELR 340
Query: 202 AQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSF 261
R+ E+E + R+ RA +R EA R +G EL
Sbjct: 341 RLREQEKEEKERRRERA----------------DRGEAERGSGGSSGDEL---------- 374
Query: 262 LEKEEQLKEAARQ---------RDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
E +E +K+ R+ D AE + +K+ ++ S EPA +E +
Sbjct: 375 REDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRV 434
Query: 313 FRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+ + Q + + + + S +R + + + +EKL LH+ +F +V+
Sbjct: 435 RPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEP--SVEEKLQKLHSEIKFALKVDS-- 490
Query: 373 PDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLR 409
PD + A + + +Q +N + +R
Sbjct: 491 PDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIR 527
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 40.0 bits (92), Expect = 0.007
Identities = 59/277 (21%), Positives = 108/277 (38%), Gaps = 42/277 (15%)
Query: 142 IPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQR 201
+P+P+ + P RPPS S SS + S V R R+ ++ E ++E R
Sbjct: 284 LPKPRGRKPKPERPPS---SSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELR 340
Query: 202 AQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSF 261
R+ E+E + R+ RA +R EA R +G EL
Sbjct: 341 RLREQEKEEKERRRERA----------------DRGEAERGSGGSSGDEL---------- 374
Query: 262 LEKEEQLKEAARQ---------RDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAEL 312
E +E +K+ R+ D AE + +K+ ++ S EPA +E +
Sbjct: 375 REDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRV 434
Query: 313 FRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVV 372
+ + Q + + + + S +R + + + +EKL LH+ +F +V+
Sbjct: 435 RPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEP--SVEEKLQKLHSEIKFALKVDS-- 490
Query: 373 PDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLR 409
PD + A + + +Q +N + +R
Sbjct: 491 PDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIR 527
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 39.7 bits (91), Expect = 0.009
Identities = 48/206 (23%), Positives = 83/206 (40%), Gaps = 29/206 (14%)
Query: 457 DATRKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKA 516
+ +R+ E + E++ E +W IHRK+++A K +A + K +E K
Sbjct: 1549 EVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK------RAQEERKLAQEEEKL 1602
Query: 517 KLKENR--NNDRKRAKEYKKELEEMKQRIQT-------------RPYLFEQVAKDLA--- 558
+E + +RK A+ Y K ++ ++ Q R Q A+ LA
Sbjct: 1603 AQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKR 1662
Query: 559 KKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGL 618
KK A++W K A EE + G+ K+++ P+ ++ ++ Q L
Sbjct: 1663 KKLAKKWE----KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718
Query: 619 EGSLEQPASPRKVLEELSHQSPENLV 644
E LE EE +Q LV
Sbjct: 1719 E-ELEWDMEELSWKEEELNQEEGKLV 1743
Score = 32.0 bits (71), Expect = 1.8
Identities = 34/170 (20%), Positives = 79/170 (46%), Gaps = 17/170 (10%)
Query: 457 DATRKRESAVRSALEKKNKADESIQWL--EIHRKKSQAMSKSVTLRAKAMDPHKSLEEVF 514
D +++ S+ +E + E ++ L E+ +++S + + + + + E
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266
Query: 515 KAKLKENRNNDRKRAKEY----KKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTL 570
+ + +E +++ KE KK+ E+ K+ +Q + +FE+ + ++++E E +
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Query: 571 KQ--AGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGL 618
++ LEE+ R K + +KE + K QE + S+R E+ L
Sbjct: 2327 EEESCSLEEEVDREK-----EILKKEKQFK----LQEQRRKSLRGRERVL 2367
Score = 30.4 bits (67), Expect = 5.3
Identities = 22/102 (21%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 460 RKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLK 519
RKRE + ++ K + I +E K + + L + + + E++ A+ K
Sbjct: 1800 RKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKL--AQRK 1857
Query: 520 ENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKE 561
EN +++R KK+L ++K ++ + QV + L +++
Sbjct: 1858 ENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEK 1899
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 39.7 bits (91), Expect = 0.009
Identities = 81/374 (21%), Positives = 145/374 (38%), Gaps = 33/374 (8%)
Query: 260 SFLEKEEQLKEAARQRDLAAT-AEAKISKQKATRRIPKSILEPALG-DKLQEAELFRKIR 317
+ ++ + QLKE R+ DL E K SK ++ K+ P L ++ + KI
Sbjct: 150 TIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKIT 209
Query: 318 IQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEG 377
I ++Q + + + + R Q L L P V +
Sbjct: 210 IWKEQYRVVQEENQHMQMTIQALQDELRI-----QRDLNQLFQQDSSSRTGEPCVAELTE 264
Query: 378 LYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPATPLPRS 437
+ FQR A+ E + FLLR R T +D + +S
Sbjct: 265 --ENFQRLHAEH----ERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS 318
Query: 438 RSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLEIHRK--------K 489
+ LS A+ + + +A + S LE+K K + ++ E+HR+ K
Sbjct: 319 KGLSAKATEEDHERTRRLAEA-EMHVHHLESLLEQKEKENSMLRE-EMHRRFENAPDSAK 376
Query: 490 SQAMSKSVTLRAKAMDPH----KSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQT 545
++A+ + ++ + + LEE + LK N + +E K++E + +
Sbjct: 377 TKALQTVIEMKDSKISSMERGLRDLEEEIQM-LKSNGALSTEEREEEMKQMEVYRSHSKF 435
Query: 546 RPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQE 605
EQ+ ++L+ KEA QW K AGL+ + GQ + + K+T++ E
Sbjct: 436 MKNKVEQLKEELSSKEA-QWEELKKKAAGLQAEI----GQVKQELSRKDTELLALQTKLE 490
Query: 606 TTKLSIRDPEQGLE 619
T D +Q +E
Sbjct: 491 TLTNQFSDSKQHIE 504
Score = 38.9 bits (89), Expect = 0.015
Identities = 79/374 (21%), Positives = 146/374 (39%), Gaps = 71/374 (18%)
Query: 231 QEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAA------RQRDLAATAEAK 284
+E +R E +Q I K+ L + S L+ + KEA+ LA++ K
Sbjct: 633 KEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKK 692
Query: 285 ISKQKATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQP 344
S+ K LE AL K +E K+ Q++ + + S+R
Sbjct: 693 DSRLKT--------LEIALEQKKEEC---LKMESQLKKAHEAALEARASPEMSDRIQHLE 741
Query: 345 RTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRN-KPFLL 403
R TR + E + + Q V+ ++ E L + + K ++ E R K
Sbjct: 742 REITRYKDE-------SSKAQAEVDRLL---EILKEVENEKNDKDKKIAELERQVKDQNK 791
Query: 404 RTANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRE 463
+ ANL+H + Q + A L +R ++ D++++ +
Sbjct: 792 KVANLKH-----------KEQVEKKKSAQMLEEARRRED-----------NLNDSSQQLQ 829
Query: 464 SAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRN 523
++R K D+ I+ LE +A+ +SV + A+ E+ A+ + R
Sbjct: 830 DSLR-------KKDDRIEELE------EALRESVQITAE--------REMVLAQEESART 868
Query: 524 NDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNK 583
N K+ +E +E++KQ +++ + LA+KE L ++ LEE +
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 584 GQGTRAVQEKETKI 597
A+ EK+ I
Sbjct: 929 EALLAAISEKDANI 942
Score = 33.9 bits (76), Expect = 0.48
Identities = 32/144 (22%), Positives = 68/144 (47%), Gaps = 16/144 (11%)
Query: 463 ESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENR 522
+ + + E+ ++ + L+ K QA + + ++ + +E +LKE R
Sbjct: 577 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQR 636
Query: 523 NNDRKRAKE----YKKELEEMKQRIQTRPYLFEQVAKDLAKKEAE----QWYLDTLKQAG 574
+ D + +E YKK+L+++K+++ + DL++KEA + + +L +G
Sbjct: 637 DRDEREKQEEIDNYKKDLKDLKEKVSL-------LQGDLSEKEASLLDLKEHASSLASSG 689
Query: 575 LEEDFVRNKGQGTRAVQEKETKIK 598
L++D R K Q+KE +K
Sbjct: 690 LKKD-SRLKTLEIALEQKKEECLK 712
>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
Length = 1280
Score = 39.3 bits (90), Expect = 0.011
Identities = 44/191 (23%), Positives = 83/191 (43%), Gaps = 15/191 (7%)
Query: 413 RPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTL-----PVHITDATRKRESAVR 467
R D G R +P LP S SL S+S + PV +R++ S+ R
Sbjct: 1012 RKVDQGGLGARAKAPPS----LPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSR 1067
Query: 468 SALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRK 527
+ K +A + Q ++ A V A + + EE + E ++ K
Sbjct: 1068 ESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEE--DVEETEQNLDEAK 1125
Query: 528 RAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT 587
A++Y++E+ ++K+R++ E+ + L +E + L +A LE+ R +
Sbjct: 1126 HAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLR---- 1181
Query: 588 RAVQEKETKIK 598
R +EK++++K
Sbjct: 1182 RQQEEKDSQMK 1192
>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
Length = 1139
Score = 39.3 bits (90), Expect = 0.011
Identities = 44/191 (23%), Positives = 83/191 (43%), Gaps = 15/191 (7%)
Query: 413 RPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTL-----PVHITDATRKRESAVR 467
R D G R +P LP S SL S+S + PV +R++ S+ R
Sbjct: 871 RKVDQGGLGARAKAPPS----LPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSR 926
Query: 468 SALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRK 527
+ K +A + Q ++ A V A + + EE + E ++ K
Sbjct: 927 ESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEE--DVEETEQNLDEAK 984
Query: 528 RAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGT 587
A++Y++E+ ++K+R++ E+ + L +E + L +A LE+ R +
Sbjct: 985 HAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLR---- 1040
Query: 588 RAVQEKETKIK 598
R +EK++++K
Sbjct: 1041 RQQEEKDSQMK 1051
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,349,138
Number of Sequences: 37866
Number of extensions: 1348079
Number of successful extensions: 8089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 425
Number of HSP's that attempted gapping in prelim test: 7191
Number of HSP's gapped (non-prelim): 1253
length of query: 647
length of database: 18,247,518
effective HSP length: 109
effective length of query: 538
effective length of database: 14,120,124
effective search space: 7596626712
effective search space used: 7596626712
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.