Guide to the Human Genome
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Search of human proteins with 22748883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748883 transmembrane protein 68 [Homo sapiens]
         (257 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748883 transmembrane protein 68 [Homo sapiens]                   536   e-153
gi|115305569 adenosine A1 receptor [Homo sapiens]                      33   0.24 
gi|4501947 adenosine A1 receptor [Homo sapiens]                        33   0.24 
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]                  33   0.32 
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]              32   0.54 
gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo sap...    30   1.6  
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid...    29   4.6  
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide...    29   4.6  
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated...    29   4.6  
gi|61888902 wax synthase 1 [Homo sapiens]                              28   6.0  
gi|5802984 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltrans...    28   7.9  
gi|22749367 transmembrane protein 154 [Homo sapiens]                   28   7.9  

>gi|22748883 transmembrane protein 68 [Homo sapiens]
          Length = 257

 Score =  536 bits (1382), Expect = e-153
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 1   MIDKNQTCGVGQDSVPYMICLIHILEEWFGVEQLEDYLNFANYLLWVFTPLILLILPYFT 60
           MIDKNQTCGVGQDSVPYMICLIHILEEWFGVEQLEDYLNFANYLLWVFTPLILLILPYFT
Sbjct: 1   MIDKNQTCGVGQDSVPYMICLIHILEEWFGVEQLEDYLNFANYLLWVFTPLILLILPYFT 60

Query: 61  IFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPE 120
           IFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPE
Sbjct: 61  IFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPE 120

Query: 121 DGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPR 180
           DGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPR
Sbjct: 121 DGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPR 180

Query: 181 EKCVEILRSGHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAKVTKNAVQALIDK 240
           EKCVEILRSGHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAKVTKNAVQALIDK
Sbjct: 181 EKCVEILRSGHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAKVTKNAVQALIDK 240

Query: 241 HQRIPGNIMSALLERFH 257
           HQRIPGNIMSALLERFH
Sbjct: 241 HQRIPGNIMSALLERFH 257


>gi|115305569 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 11/29 (37%), Positives = 20/29 (68%)

Query: 36  DYLNFANYLLWVFTPLILLILPYFTIFLL 64
           +Y+ + N+ +WV  PL+L++L Y  +F L
Sbjct: 178 EYMVYFNFFVWVLPPLLLMVLIYLEVFYL 206


>gi|4501947 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 11/29 (37%), Positives = 20/29 (68%)

Query: 36  DYLNFANYLLWVFTPLILLILPYFTIFLL 64
           +Y+ + N+ +WV  PL+L++L Y  +F L
Sbjct: 178 EYMVYFNFFVWVLPPLLLMVLIYLEVFYL 206


>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
          Length = 1966

 Score = 32.7 bits (73), Expect = 0.32
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 17/91 (18%)

Query: 17   YMICLIHILEEWFG--VEQLEDYLN----FANYLLWVFTPLILLILPY-----FTIF--- 62
            ++ CL+ +L +      +QL D  N      ++LL +FT   +LI P      +T+    
Sbjct: 915  FVACLLSLLRQMTDRHYQQLLDSFNTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMRLV 974

Query: 63   ---LLYLTIIFLHIYKRKNVLKEAYSHNLWD 90
               ++  T+++L    RKN L E + + +WD
Sbjct: 975  ANNVIITTVLYLSDALRKNFLNENFDYKIWD 1005


>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
          Length = 318

 Score = 32.0 bits (71), Expect = 0.54
 Identities = 12/42 (28%), Positives = 24/42 (57%)

Query: 36  DYLNFANYLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRK 77
           DY+ + ++L W+F PL+++   Y  IF +    + L++   K
Sbjct: 175 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSK 216


>gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo
           sapiens]
          Length = 1124

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 16/93 (17%)

Query: 181 EKCVEILRSGHLLAISPGGVREALI----------------SDETYNIVWGHRRGFAQVA 224
           E CV+++R G      PG VR                    S  T N+ W      ++  
Sbjct: 514 ELCVQLVRRGEGGEGHPGPVRRFTTASIGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDD 573

Query: 225 IDAKVTKNAVQALIDKHQRIPGNIMSALLERFH 257
              +V + +VQ    ++ ++PGN+ S LL   H
Sbjct: 574 FYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLH 606


>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
            isoform 2 [Homo sapiens]
          Length = 4097

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 116  EKIPEDGPALIIFYHGA-----IPIDFYYFMAKIFIHKGRTCRVVADHFV 160
            + +P D P+ + F HG      +P++   F+AK+ I+     R  A H++
Sbjct: 2116 DSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWL 2165


>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
            isoform 1 [Homo sapiens]
          Length = 4128

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 116  EKIPEDGPALIIFYHGA-----IPIDFYYFMAKIFIHKGRTCRVVADHFV 160
            + +P D P+ + F HG      +P++   F+AK+ I+     R  A H++
Sbjct: 2116 DSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWL 2165


>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
            catalytic polypeptide [Homo sapiens]
          Length = 4096

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 116  EKIPEDGPALIIFYHGA-----IPIDFYYFMAKIFIHKGRTCRVVADHFV 160
            + +P D P+ + F HG      +P++   F+AK+ I+     R  A H++
Sbjct: 2116 DSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWL 2165


>gi|61888902 wax synthase 1 [Homo sapiens]
          Length = 328

 Score = 28.5 bits (62), Expect = 6.0
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 149 GRTCRVVADHFVFKIPGFS--LLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALIS 206
           G T  +    + FKIP     L+    C++  P    +    +G+L+ I  GGV EAL S
Sbjct: 129 GITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSHGTGNLVGIVVGGVGEALQS 188

Query: 207 -DETYNIVWGHRRGFAQVAI 225
              T  ++   R+GF + A+
Sbjct: 189 VPNTTTLILQKRKGFVRTAL 208


>gi|5802984 UDP-GlcNAc:betaGal
           beta-1,3-N-acetylglucosaminyltransferase 1 [Homo
           sapiens]
          Length = 415

 Score = 28.1 bits (61), Expect = 7.9
 Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 85  SHNLWDGARKTV--ATLWDGHAAVWHGYEVHGMEKIPEDGPALIIFYHGAIPIDFYY 139
           S  LW G R+ +  +  W G A V   +E+    ++P +   L+  Y       FYY
Sbjct: 233 SEGLWRGLREMLDQSNQWGGTALVVPAFEIRRARRMPMNKNELVQLYQVGEVRPFYY 289


>gi|22749367 transmembrane protein 154 [Homo sapiens]
          Length = 183

 Score = 28.1 bits (61), Expect = 7.9
 Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 8/48 (16%)

Query: 39  NFANYLLWVFTPLILLILPYFTIFLLYLTIIFL-HIYKRKNVLKEAYS 85
           N   ++L V  PLILL+L       L L+++FL   YKRK   +E  S
Sbjct: 72  NQLEFILMVLIPLILLVL-------LLLSVVFLATYYKRKRTKQEPSS 112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.145    0.472 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,031,414
Number of Sequences: 37866
Number of extensions: 430222
Number of successful extensions: 1051
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1040
Number of HSP's gapped (non-prelim): 15
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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