Search of human proteins with 22748623

Search of human proteins with 22748623

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748623 Fanconi anemia-associated protein, 24 kDa [Homo
sapiens]
         (215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748623 Fanconi anemia-associated protein, 24 kDa [Homo sapi...   424   e-119
gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]     31   0.91 
gi|33286444 mastermind-like 2 [Homo sapiens]                           30   2.0  
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    28   5.9  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    28   5.9  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    28   5.9  
gi|189217874 neurensin 1 [Homo sapiens]                                28   5.9  
gi|115647981 glutamine and serine rich 1 [Homo sapiens]                28   7.7  

>gi|22748623 Fanconi anemia-associated protein, 24 kDa [Homo
           sapiens]
          Length = 215

 Score =  424 bits (1090), Expect = e-119
 Identities = 215/215 (100%), Positives = 215/215 (100%)

Query: 1   MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILY 60
           MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILY
Sbjct: 1   MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILY 60

Query: 61  VTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVA 120
           VTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVA
Sbjct: 61  VTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVA 120

Query: 121 SQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQK 180
           SQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQK
Sbjct: 121 SQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQK 180

Query: 181 FPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR 215
           FPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR
Sbjct: 181 FPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR 215


>gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]
          Length = 2048

 Score = 30.8 bits (68), Expect = 0.91
 Identities = 33/175 (18%), Positives = 84/175 (48%), Gaps = 16/175 (9%)

Query: 49   DFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNL--KGIVVVEKTRM----SEQYFP 102
            D+ +SNR  +   ++++++      K + ++++  ++  +  V+VEK R     + + F 
Sbjct: 1854 DYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFR 1913

Query: 103  ALQKF-----TVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEP 157
              + +     T++  G+ +L  + Q E + L+ +L      E  KN  +     +  ++ 
Sbjct: 1914 RTKSYDSLLTTLIGAGIRILFSSCQEETADLLKEL---SLVEQRKNVGIHVPTVVNSNKS 1970

Query: 158  SLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQV--VGQAVAQQIHAF 210
              L+    IP +  + A  +  +F S+++++N+S+ E+     V    A++I+ +
Sbjct: 1971 EALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRY 2025


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)

Query: 122 QMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKF 181
           Q ++S    Q  Q+Q ++  +     +++     +PS  +  Q +P    +++PL LQ+ 
Sbjct: 631 QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSS-QPAQSLPSQPLLRSPLPLQQK 689

Query: 182 PSIQQLSNASIGELEQVVGQAVAQQIHAFFTQ 213
             +QQ+ N  I  +   V Q   Q  H+   Q
Sbjct: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQ 721


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform
           4 [Homo sapiens]
          Length = 3321

 Score = 28.1 bits (61), Expect = 5.9
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 5/128 (3%)

Query: 92  EKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKE-PSKNPLLGKKR 150
           E   M E     ++K  VL  G +    ASQ+    ++ Q + E++KE  S+   + +K 
Sbjct: 55  EYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKL 114

Query: 151 ALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIG----ELEQVVGQAVAQQ 206
             L S     +  QQ+  +G+    L       +Q L +A+      E E    QA  +Q
Sbjct: 115 QYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQ 174

Query: 207 IHAFFTQP 214
             A  T P
Sbjct: 175 AQATLTSP 182


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 28.1 bits (61), Expect = 5.9
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 5/128 (3%)

Query: 92   EKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKE-PSKNPLLGKKR 150
            E   M E     ++K  VL  G +    ASQ+    ++ Q + E++KE  S+   + +K 
Sbjct: 5460 EYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKL 5519

Query: 151  ALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIG----ELEQVVGQAVAQQ 206
              L S     +  QQ+  +G+    L       +Q L +A+      E E    QA  +Q
Sbjct: 5520 QYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQ 5579

Query: 207  IHAFFTQP 214
              A  T P
Sbjct: 5580 AQATLTSP 5587


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 28.1 bits (61), Expect = 5.9
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 5/128 (3%)

Query: 92   EKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKE-PSKNPLLGKKR 150
            E   M E     ++K  VL  G +    ASQ+    ++ Q + E++KE  S+   + +K 
Sbjct: 5531 EYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKL 5590

Query: 151  ALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIG----ELEQVVGQAVAQQ 206
              L S     +  QQ+  +G+    L       +Q L +A+      E E    QA  +Q
Sbjct: 5591 QYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQ 5650

Query: 207  IHAFFTQP 214
              A  T P
Sbjct: 5651 AQATLTSP 5658


>gi|189217874 neurensin 1 [Homo sapiens]
          Length = 195

 Score = 28.1 bits (61), Expect = 5.9
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 7/90 (7%)

Query: 103 ALQKFTVLDL----GMVLLPVASQMEASCLVIQL-VQEQTKEPSKNPLLGKKRALLLSEP 157
           A+Q  + LD+    G VL  +     A CL++ + V+  +KE  +  L  K +  +    
Sbjct: 105 AVQFNSALDMYKLAGAVLFCIGGTSMAGCLLMSVFVKSYSKE--EKFLQQKFKERIADIK 162

Query: 158 SLLRTVQQIPGVGKVKAPLLLQKFPSIQQL 187
           +  + V + PG G+ K P+ L +  ++Q L
Sbjct: 163 AHTQPVTKAPGPGETKIPVTLSRVQNVQPL 192


>gi|115647981 glutamine and serine rich 1 [Homo sapiens]
          Length = 1735

 Score = 27.7 bits (60), Expect = 7.7
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 8/76 (10%)

Query: 136 QTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASI--- 192
           Q   P+   LL     L + + S+L+      G+G+VKA L  Q+  S QQ+ +  +   
Sbjct: 717 QASLPNTQVLLDSACDLQILQQSILQA-----GLGQVKASLQAQRVQSPQQIVHPFLQME 771

Query: 193 GELEQVVGQAVAQQIH 208
           G + Q  G    QQ+H
Sbjct: 772 GHVIQSNGDHSQQQLH 787


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,804,327
Number of Sequences: 37866
Number of extensions: 308774
Number of successful extensions: 722
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 720
Number of HSP's gapped (non-prelim): 8
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.