Guide to the Human Genome
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Search of human proteins with 224451116

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224451116 Mu-2 related death-inducing protein [Homo sapiens]
         (490 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224451116 Mu-2 related death-inducing protein [Homo sapiens]       998   0.0  
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo...    45   1e-04
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof...    40   0.004
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso...    39   0.014
gi|119874201 furry-like [Homo sapiens]                                 30   3.8  
gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]          30   5.0  
gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]          30   5.0  
gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]          30   5.0  
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                    30   6.5  
gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8 is...    29   8.5  
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]              29   8.5  

>gi|224451116 Mu-2 related death-inducing protein [Homo sapiens]
          Length = 490

 Score =  998 bits (2580), Expect = 0.0
 Identities = 490/490 (100%), Positives = 490/490 (100%)

Query: 1   MAQRAVWLISHEPGTPLCGTVRFSRRYPTVEKRARVFNGASYVPVPEDGPFLKALLFELR 60
           MAQRAVWLISHEPGTPLCGTVRFSRRYPTVEKRARVFNGASYVPVPEDGPFLKALLFELR
Sbjct: 1   MAQRAVWLISHEPGTPLCGTVRFSRRYPTVEKRARVFNGASYVPVPEDGPFLKALLFELR 60

Query: 61  LLDDDKDFVESRDSCSRINKTSIYGLLIGGEELWPVVAFLKNDMIYACVPLVEQTLSPRP 120
           LLDDDKDFVESRDSCSRINKTSIYGLLIGGEELWPVVAFLKNDMIYACVPLVEQTLSPRP
Sbjct: 61  LLDDDKDFVESRDSCSRINKTSIYGLLIGGEELWPVVAFLKNDMIYACVPLVEQTLSPRP 120

Query: 121 PLISVSGVSQGFEFLFGIQDFLYSGQKNDSELNTKLSQLPDLLLQACPFGTLLDANLQNS 180
           PLISVSGVSQGFEFLFGIQDFLYSGQKNDSELNTKLSQLPDLLLQACPFGTLLDANLQNS
Sbjct: 121 PLISVSGVSQGFEFLFGIQDFLYSGQKNDSELNTKLSQLPDLLLQACPFGTLLDANLQNS 180

Query: 181 LDNTNFASVTQPQKQPAWKTGTYKGKPQVSISITEKVKSMQYDKQGIADTWQVVGTVTCK 240
           LDNTNFASVTQPQKQPAWKTGTYKGKPQVSISITEKVKSMQYDKQGIADTWQVVGTVTCK
Sbjct: 181 LDNTNFASVTQPQKQPAWKTGTYKGKPQVSISITEKVKSMQYDKQGIADTWQVVGTVTCK 240

Query: 241 CDLEGIMPNVTISLSLPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFP 300
           CDLEGIMPNVTISLSLPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFP
Sbjct: 241 CDLEGIMPNVTISLSLPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFP 300

Query: 301 FTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLHESVKNNFEFCEAHIPF 360
           FTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLHESVKNNFEFCEAHIPF
Sbjct: 301 FTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLHESVKNNFEFCEAHIPF 360

Query: 361 YNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHEKQPFD 420
           YNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHEKQPFD
Sbjct: 361 YNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHEKQPFD 420

Query: 421 PICTGETAYLKLHFRILDYTLTGCYADQHSVQVFASGKPKISAHRKLISSDYYIWNSKAP 480
           PICTGETAYLKLHFRILDYTLTGCYADQHSVQVFASGKPKISAHRKLISSDYYIWNSKAP
Sbjct: 421 PICTGETAYLKLHFRILDYTLTGCYADQHSVQVFASGKPKISAHRKLISSDYYIWNSKAP 480

Query: 481 APVTYGSLLL 490
           APVTYGSLLL
Sbjct: 481 APVTYGSLLL 490


>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
           sapiens]
          Length = 423

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 58/237 (24%), Positives = 91/237 (38%), Gaps = 42/237 (17%)

Query: 197 AWKT-GTYKGKPQVSISITEKVKSMQYDKQGIADTWQVVGTVTCKCDLEGIMPNVTISLS 255
           +W++ G    K +V I + E V ++  +  G     ++VGT+  K  L G MP + + L+
Sbjct: 158 SWRSEGIKYKKNEVFIDVIESV-NLLVNANGSVLLSEIVGTIKLKVFLSG-MPELRLGLN 215

Query: 256 ----------LPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFPFTPPL 305
                            L+D+  H CV                  S F       F PP 
Sbjct: 216 DRVLFELTGRSKNKSVELEDVKFHQCVRL----------------SRFDNDRTISFIPPD 259

Query: 306 ESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKL-----HESVKNNFEFCEAHIPF 360
             F L  Y     V P++    + E+    R+ I +K       +SV N  E     +P 
Sbjct: 260 GDFELMSYRLSTQVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEI-SVPVPS 318

Query: 361 YNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHEKQ 417
               P     +KTS G  +   E++++IW I + FP   E  +     FG  S EK+
Sbjct: 319 DADSP----RFKTSVGSAKYVPERNVVIWSI-KSFPGGKEYLM--RAHFGLPSVEKE 368


>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
           2 [Homo sapiens]
          Length = 423

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 65/298 (21%), Positives = 107/298 (35%), Gaps = 46/298 (15%)

Query: 128 VSQGFEFLFGIQDFL--YSGQKNDSELNTKLSQLPDLLLQACPFG---TLLDANLQNSLD 182
           VS  F FL+ +      Y  +  +  +      + +LL +   FG   T     LQ  + 
Sbjct: 77  VSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYIT 136

Query: 183 NTNFASVTQPQKQPA-------WKT-GTYKGKPQVSISITEKVKSMQYDKQGIADTWQVV 234
                  T   + PA       W++ G    K +V + + E V ++     G     ++V
Sbjct: 137 QEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESV-NLLVSANGNVLRSEIV 195

Query: 235 GTVTCKCDLEGIMPNVTISLSLP----------TNGSPLQDILVHPCVTSLDSAILTSSS 284
           G++  +  L G MP + + L+            +    L+D+  H CV            
Sbjct: 196 GSIKMRVFLSG-MPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRL---------- 244

Query: 285 IDAMDDSAFSGPYKFPFTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLH 344
                 S F       F PP   F L  Y     V P++    + E+    RI   +K  
Sbjct: 245 ------SRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAK 298

Query: 345 ESVK--NNFEFCEAHIPFYNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSME 400
              K  +     E HIP  N       ++KT+ G ++   E S ++W I + FP   E
Sbjct: 299 SQFKRRSTANNVEIHIPVPNDADSP--KFKTTVGSVKWVPENSEIVWSI-KSFPGGKE 353


>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
           isoform 1 [Homo sapiens]
          Length = 435

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 42/181 (23%), Positives = 67/181 (37%), Gaps = 32/181 (17%)

Query: 232 QVVGTVTCKCDLEGIMPNVTISLSLP----------TNGSPLQDILVHPCVTSLDSAILT 281
           ++VG++  +  L G MP + + L+            +    L+D+  H CV         
Sbjct: 205 EIVGSIKMRVFLSG-MPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRL------- 256

Query: 282 SSSIDAMDDSAFSGPYKFPFTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINL 341
                    S F       F PP   F L  Y     V P++    + E+    RI   +
Sbjct: 257 ---------SRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMI 307

Query: 342 KLHESVK--NNFEFCEAHIPFYNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSM 399
           K     K  +     E HIP  N       ++KT+ G ++   E S ++W I + FP   
Sbjct: 308 KAKSQFKRRSTANNVEIHIPVPNDADSP--KFKTTVGSVKWVPENSEIVWSI-KSFPGGK 364

Query: 400 E 400
           E
Sbjct: 365 E 365


>gi|119874201 furry-like [Homo sapiens]
          Length = 3013

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 430  LKLHFRILDYTLTGC-YADQHSVQVFASGKPKISAHRKLISSDYYIWNSKAPAPVTY 485
            L  HF I +  + G  Y DQHS     +GKPK+ A  +  SS     NS A  PV++
Sbjct: 2293 LDFHFDISETPIIGNKYGDQHSA-AGRNGKPKVIAVTRSTSSTSSGSNSNALVPVSW 2348


>gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]
          Length = 1660

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 154 TKLSQLPDLLLQACPFGTLLDANLQNSLDNTNFASVTQPQK 194
           T  S   DL+LQ  P  TL   N + S+D++  AS  +P K
Sbjct: 648 TLQSSNSDLVLQTLPLSTLESENAKESMDDSGKASQEEPLK 688


>gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]
          Length = 1815

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 154 TKLSQLPDLLLQACPFGTLLDANLQNSLDNTNFASVTQPQK 194
           T  S   DL+LQ  P  TL   N + S+D++  AS  +P K
Sbjct: 648 TLQSSNSDLVLQTLPLSTLESENAKESMDDSGKASQEEPLK 688


>gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]
          Length = 2248

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 154 TKLSQLPDLLLQACPFGTLLDANLQNSLDNTNFASVTQPQK 194
           T  S   DL+LQ  P  TL   N + S+D++  AS  +P K
Sbjct: 648 TLQSSNSDLVLQTLPLSTLESENAKESMDDSGKASQEEPLK 688


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 31/139 (22%), Positives = 57/139 (41%), Gaps = 20/139 (14%)

Query: 314 TSQVPVPPILGFYQMKEEEVQLRITINL---KLH-------------ESVKNNFEFCEAH 357
           T  + +  I GF + ++ E + ++ +N+   K+H             E V+       A+
Sbjct: 771 TLDIGILDIFGFEEFQKNEFE-QLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETAY 829

Query: 358 IPFYNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHEKQ 417
            P    G +     K S G L +  E+S +IW +   FPK ++  L  + T    S  K 
Sbjct: 830 SPGNQNGVLDFFFQKPS-GFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKD 888

Query: 418 PFDPICTGE--TAYLKLHF 434
               +   +  TA+  +H+
Sbjct: 889 GNGNVALKDHGTAFTIMHY 907


>gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
           isoform 1 [Homo sapiens]
          Length = 495

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 11/115 (9%)

Query: 249 NVTISLSLPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFPFTPPLESF 308
           + T  LSLP N +         CV+++   +   SS    +D AF G Y+ P      +F
Sbjct: 294 HATPPLSLPQNLTVEGTGNPGACVSAIRE-LFNFSSCQGQEDCAFDGVYQPPLRGQFYAF 352

Query: 309 NLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLHESVKNNFEFCEAHIPFYNR 363
           +  +YT          F+ +     Q   T+N  + E  +  ++  EA  P  +R
Sbjct: 353 SNFYYT----------FHFLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDR 397


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 3/64 (4%)

Query: 247  MPNVTISLS---LPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFPFTP 303
            +P+ TI+ S   +PT  SP   I+  P + SL + + T+S++        S    +PFT 
Sbjct: 2147 LPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTA 2206

Query: 304  PLES 307
             + S
Sbjct: 2207 TVSS 2210


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,708,931
Number of Sequences: 37866
Number of extensions: 879922
Number of successful extensions: 1647
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1638
Number of HSP's gapped (non-prelim): 15
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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