Search of human proteins with 224451073

Search of human proteins with 224451073

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like
isoform 1 precursor [Homo sapiens]
         (368 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isofo...   739   0.0  
gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isofo...   614   e-176
gi|53759134 endonuclease G precursor [Homo sapiens]                   179   4e-45
gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ...    39   0.006
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ...    39   0.010
gi|148225659 endonuclease domain containing 1 [Homo sapiens]           34   0.24 
gi|46852174 kinesin family member 3A [Homo sapiens]                    32   1.2  
gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]          30   3.4  
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre...    29   5.9  

>gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isoform
           1 precursor [Homo sapiens]
          Length = 368

 Score =  739 bits (1907), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKA 60
           MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKA
Sbjct: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKA 60

Query: 61  VLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNI 120
           VLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNI
Sbjct: 61  VLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNI 120

Query: 121 PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM 180
           PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM
Sbjct: 121 PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM 180

Query: 181 YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS 240
           YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS
Sbjct: 181 YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS 240

Query: 241 TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK 300
           TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK
Sbjct: 241 TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK 300

Query: 301 LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS 360
           LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS
Sbjct: 301 LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS 360

Query: 361 GTQIRKPS 368
           GTQIRKPS
Sbjct: 361 GTQIRKPS 368


>gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isoform
           2 precursor [Homo sapiens]
          Length = 318

 Score =  614 bits (1583), Expect = e-176
 Identities = 318/368 (86%), Positives = 318/368 (86%), Gaps = 50/368 (13%)

Query: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKA 60
           MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPD      
Sbjct: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPD------ 54

Query: 61  VLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNI 120
                                                       GDADRKHCKFKPDPNI
Sbjct: 55  --------------------------------------------GDADRKHCKFKPDPNI 70

Query: 121 PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM 180
           PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM
Sbjct: 71  PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM 130

Query: 181 YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS 240
           YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS
Sbjct: 131 YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS 190

Query: 241 TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK 300
           TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK
Sbjct: 191 TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK 250

Query: 301 LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS 360
           LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS
Sbjct: 251 LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS 310

Query: 361 GTQIRKPS 368
           GTQIRKPS
Sbjct: 311 GTQIRKPS 318


>gi|53759134 endonuclease G precursor [Homo sapiens]
          Length = 297

 Score =  179 bits (454), Expect = 4e-45
 Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 4/232 (1%)

Query: 53  PDGSAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHC 112
           P G      L ++G P    + +   ++ L YD   R   WV+E +   ++ GD DR+ C
Sbjct: 55  PGGPRGPGELAKYGLPGLA-QLKSRESYVLCYDPRTRGALWVVEQLRPERLRGDGDRREC 113

Query: 113 KFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNS 172
            F+ D ++     A N DY GSG+ RGH+A A N+++S KAM +TFYLSN+ PQ    N 
Sbjct: 114 DFREDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQKAMDDTFYLSNVAPQVPHLNQ 173

Query: 173 GYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVI 232
             WN +E Y R LT  +++V+V +GPL LP+T  DGK  V YQVIG+++VAVP+H +KV+
Sbjct: 174 NAWNNLEKYSRSLTRSYQNVYVCTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVL 233

Query: 233 LARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHL 284
           +   +    E   L  +V+PN  +     L  F V ++ +E+ SGL+F P++
Sbjct: 234 ILEAAGGQIE---LRTYVMPNAPVDEAIPLERFLVPIESIERASGLLFVPNI 282


>gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
           [Homo sapiens]
          Length = 875

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 54/250 (21%), Positives = 106/250 (42%), Gaps = 38/250 (15%)

Query: 77  YTNHALSYDQAKRVPRWVLEHISKSKIMGDADR-----KHCKFKPDPNIPPTFSAFNEDY 131
           +  +   + +A R+P W    + +   +GD          C  + D  +PP+ S     Y
Sbjct: 627 HREYVSGFGKAMRMPMWSSYTVPQ---LGDTSPLPPTVPDC-LRADVRVPPSESQKCSFY 682

Query: 132 VGS-GWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCRELTER 188
           +     + G + P  +N+ +S +  +    SN+VP  ++F     Y++ + +  +  TER
Sbjct: 683 LADKNITHGFLYPPASNR-TSDSQYDALITSNLVPMYEEFRKMWDYFHSV-LLIKHATER 740

Query: 189 FEDVWVVSGPLTLPQTRG--DGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLAL 246
              V VVSGP+      G  D    ++  +   D V +P+H + V+ + ++   T     
Sbjct: 741 -NGVNVVSGPIFDYNYDGHFDAPDEITKHLANTD-VPIPTHYFVVLTSCKNKSHTPENCP 798

Query: 247 G-----AFVVPN-------------EAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTS 288
           G      F++P+             EA+  + + T     ++D+E L+GL F+   D+  
Sbjct: 799 GWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQ--DKVQ 856

Query: 289 DIRNICSVDT 298
            +  I  + T
Sbjct: 857 PVSEILQLKT 866


>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Homo sapiens]
          Length = 925

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 29/223 (13%)

Query: 84  YDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPD--PNIPPTFSAFNEDYVGSGWSRGHM 141
           Y Q   +P W    + ++      D  +C ++    P  P    +F ++   +  S G +
Sbjct: 683 YSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKN--NTKVSYGFL 740

Query: 142 APAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPL 199
           +P   NK SS   +E    +NIVP  Q F     Y++  +   R+  E    V VVSGP+
Sbjct: 741 SPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFH--DTLLRKYAEERNGVNVVSGPV 798

Query: 200 TLPQTRGDGKKIVSY----QVIGEDNVAVPSHLYKVILARRSSVST----EPLALGAFVV 251
                 G    + +     +VI    + +P+H + V+ + + +  T    E L   AF++
Sbjct: 799 FDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFIL 858

Query: 252 P-------------NEAIGFQPQLTEFQVSLQDLEKLSGLVFF 281
           P             +++   +  L   +  + D+E ++GL F+
Sbjct: 859 PHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFY 901


>gi|148225659 endonuclease domain containing 1 [Homo sapiens]
          Length = 500

 Score = 33.9 bits (76), Expect = 0.24
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 22/109 (20%)

Query: 126 AFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCR 183
           A N DY+ S + RG + P      SS     TF L+N  P  Q F     Y N   +  R
Sbjct: 129 ALNTDYLDSDYQRGQLYPF---SLSSDVQVATFTLTNSAPMTQSFQER-WYVNLHSLMDR 184

Query: 184 ELTERF---EDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLY 229
            LT +    ED+++++G  T+P           Y+V  +D VAVP  ++
Sbjct: 185 ALTPQCGSGEDLYILTG--TVPS---------DYRV--KDKVAVPEFVW 220


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 3/47 (6%)

Query: 321 SVLRLEKIMENLKN-AEI--EPDDYFMSRYEKKLEELKAKEQSGTQI 364
           S LR     +N+KN A I  +P D  + +++K++EELK K + G +I
Sbjct: 334 STLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEI 380


>gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]
          Length = 590

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 16/69 (23%), Positives = 31/69 (44%)

Query: 273 EKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENL 332
           +K   ++ FPH+ +  D+R     D C L D Q     L  +  E    +    + ++++
Sbjct: 28  KKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQPIGRLLFRQFCETRPGLECYIQFLDSV 87

Query: 333 KNAEIEPDD 341
              E+ PD+
Sbjct: 88  AEYEVTPDE 96


>gi|41152097 DNA segment on chromosome X and Y (unique) 155
           expressed sequence isoform 1 [Homo sapiens]
          Length = 695

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 314 RKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQ 363
           RK +    + R  K  E L+  E +  D  + R +KKLE+L+A+EQ   Q
Sbjct: 304 RKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQ 353


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,638,852
Number of Sequences: 37866
Number of extensions: 621999
Number of successful extensions: 1524
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1515
Number of HSP's gapped (non-prelim): 12
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.