Guide to the Human Genome
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Search of human proteins with 222136639

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222136639 methylenetetrahydrofolate dehydrogenase 1 [Homo
sapiens]
         (935 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222136639 methylenetetrahydrofolate dehydrogenase 1 [Homo sap...  1851   0.0  
gi|36796743 methylenetetrahydrofolate dehydrogenase (NADP+ depen...  1115   0.0  
gi|94721354 methylenetetrahydrofolate dehydrogenase 2 precursor ...   197   4e-50
gi|222418558 methylenetetrahydrofolate dehydrogenase 2-like [Hom...   190   6e-48
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]         32   2.1  
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]              31   4.7  
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                       31   6.2  
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                        31   6.2  
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    31   6.2  
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...    31   6.2  
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]        30   8.0  

>gi|222136639 methylenetetrahydrofolate dehydrogenase 1 [Homo
           sapiens]
          Length = 935

 Score = 1851 bits (4795), Expect = 0.0
 Identities = 935/935 (100%), Positives = 935/935 (100%)

Query: 1   MAPAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAA 60
           MAPAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAA
Sbjct: 1   MAPAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAA 60

Query: 61  EEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAP 120
           EEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAP
Sbjct: 61  EEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAP 120

Query: 121 EKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAP 180
           EKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAP
Sbjct: 121 EKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAP 180

Query: 181 MHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINY 240
           MHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINY
Sbjct: 181 MHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINY 240

Query: 241 VPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKP 300
           VPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKP
Sbjct: 241 VPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKP 300

Query: 301 GKWMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSAL 360
           GKWMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSAL
Sbjct: 301 GKWMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSAL 360

Query: 361 ERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGI 420
           ERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGI
Sbjct: 361 ERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGI 420

Query: 421 KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV 480
           KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV
Sbjct: 421 KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV 480

Query: 481 PSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRF 540
           PSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRF
Sbjct: 481 PSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRF 540

Query: 541 LRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPV 600
           LRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPV
Sbjct: 541 LRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPV 600

Query: 601 SAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVG 660
           SAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVG
Sbjct: 601 SAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVG 660

Query: 661 PEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLP 720
           PEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLP
Sbjct: 661 PEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLP 720

Query: 721 KAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAF 780
           KAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAF
Sbjct: 721 KAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAF 780

Query: 781 DAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIE 840
           DAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIE
Sbjct: 781 DAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIE 840

Query: 841 LLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFL 900
           LLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFL
Sbjct: 841 LLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFL 900

Query: 901 YPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF 935
           YPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF
Sbjct: 901 YPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF 935


>gi|36796743 methylenetetrahydrofolate dehydrogenase (NADP+
           dependent) 1-like [Homo sapiens]
          Length = 978

 Score = 1115 bits (2884), Expect = 0.0
 Identities = 572/917 (62%), Positives = 707/917 (77%), Gaps = 23/917 (2%)

Query: 21  KNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESE 80
           K  ++ L+E+ P F P LAI+Q G   D NL   +    AEE G+  THI LP  ++E+E
Sbjct: 83  KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPDSSEAE 139

Query: 81  VMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGKLARGDL 140
           ++  I  +NED+ VHG  +Q+   SEN + + +V+NA+ PEKDVDG+T IN GKL RGD 
Sbjct: 140 IIDEILKINEDTRVHGLALQI---SEN-LFSNKVLNALKPEKDVDGVTDINLGKLVRGDA 195

Query: 141 NDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTA 200
           ++CF+    K  +EL++++GV + G+  +VVG    + A +  L     +   +   KT 
Sbjct: 196 HECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSIQWKTR 255

Query: 201 HLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGD--VAY 258
            L  ++++ DI+V+ + +PE +   WI+PG  V++C  +++      +G+   G   + +
Sbjct: 256 QLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNCSHDFL------SGKVGCGSPRIHF 309

Query: 259 DEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKPGKWMIQYNNLNLKTPVPS 318
               E    I         +  A+ +Q+ V S +R+L + +  +W +    L   +PVPS
Sbjct: 310 GGLIEEDDVIL--------LAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVPS 361

Query: 319 DIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGIT 378
           DI+ISR   PK +  LA+EIGLL++E+E+YG++KAKV LS LERLK + DGKYV+V GIT
Sbjct: 362 DIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVRLSVLERLKDQADGKYVLVAGIT 421

Query: 379 PTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEF 438
           PTPLGEGKST TIGLVQAL AHL  N FAC+RQPSQGPTFG+KGGAAGGGY+QVIPMEEF
Sbjct: 422 PTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEF 481

Query: 439 NLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRRFSDIQIRRLK 498
           NLHLTGDIHAITAANNL+AAAID RI HE TQTDKAL+NRLVP VNGVR FS+IQ+ RLK
Sbjct: 482 NLHLTGDIHAITAANNLLAAAIDTRILHENTQTDKALYNRLVPLVNGVREFSEIQLARLK 541

Query: 499 RLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRT 558
           +LGI KTDP+TLT+EE+++FARLDIDP TITWQRVLDTNDRFLRKITIGQ  TEKGH R 
Sbjct: 542 KLGINKTDPSTLTEEEVSKFARLDIDPSTITWQRVLDTNDRFLRKITIGQGNTEKGHYRQ 601

Query: 559 AQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPVSAEDLGVSGALTVLMKDA 618
           AQFDI+VASEIMAVLALT SL DM+ RLG+MVVAS K G+PV+A+DLGV+GALTVLMKDA
Sbjct: 602 AQFDIAVASEIMAVLALTDSLADMKARLGRMVVASDKSGQPVTADDLGVTGALTVLMKDA 661

Query: 619 IKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGME 678
           IKPNLMQTLEGTPVFVHAGPFANIAHGNSS++AD+IALKLVG EGFVVTEAGFGADIGME
Sbjct: 662 IKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGADIGME 721

Query: 679 KFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYIQENLELVEKGFSNL 738
           KFFNIKCR SGL P+VVVLVATVRALKMHGGGP+VTAG+PL K Y +EN++LV  G  NL
Sbjct: 722 KFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEENIQLVADGCCNL 781

Query: 739 KKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAFDAVKCTHWAEGGKGALAL 798
           +KQI+  ++FG+PVVVA+N FKTDT +E+DL+  L++  GAFDAV C HW+ GGKG++ L
Sbjct: 782 QKQIQITQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSVGGKGSVDL 841

Query: 799 AQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFG 858
           A+AV+ AA   S FQ LYD+++P+ DKIR IAQ +YGA DIEL PEAQ K + YT+QGFG
Sbjct: 842 ARAVREAASKRSRFQFLYDVQVPIVDKIRTIAQAVYGAKDIELSPEAQAKIDRYTQQGFG 901

Query: 859 NLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPC 918
           NLPICMAKTHLSLSH P++KGVP  FILPI D+RAS+GAGF+YPLVGTMSTMPGLPTRPC
Sbjct: 902 NLPICMAKTHLSLSHQPDKKGVPRDFILPISDVRASIGAGFIYPLVGTMSTMPGLPTRPC 961

Query: 919 FYDIDLDPETEQVNGLF 935
           FYDIDLD ETEQV GLF
Sbjct: 962 FYDIDLDTETEQVKGLF 978


>gi|94721354 methylenetetrahydrofolate dehydrogenase 2 precursor
           [Homo sapiens]
          Length = 350

 Score =  197 bits (501), Expect = 4e-50
 Identities = 119/304 (39%), Positives = 177/304 (58%), Gaps = 20/304 (6%)

Query: 4   AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
           A +++G++++ QI+  ++ +V +         P L+++ VG    S+ Y+  K +AA  +
Sbjct: 37  AVVISGRKLAQQIKQEVRQEVEEWVAS-GNKRPHLSVILVGENPASHSYVLNKTRAAAVV 95

Query: 64  GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
           GI +  I  P + +E E++  I  LN D  V G LVQLPL     I+   + NA++P+KD
Sbjct: 96  GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEH--IDERRICNAVSPDKD 153

Query: 124 VDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHD 183
           VDG   IN G++     +   +P TP G  E+IK TG+P  G++ VV GRSK VG P+  
Sbjct: 154 VDGFHVINVGRMCLDQYS--MLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAM 211

Query: 184 LLLWN--------NATVTTCHSKTA--HLDEEVNKGDILVVATGQPEMVKGEWIKPGAIV 233
           LL  +        +ATVT  H  T    L +     DI++ A G P ++  + IK GA V
Sbjct: 212 LLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAV 271

Query: 234 IDCGINYVPDD--KKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESA 291
           ID GIN V D    KP   K+VGDV ++  +++A +ITPVPGGVGPMTVAMLM++T+ +A
Sbjct: 272 IDVGINRVHDPVTAKP---KLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAA 328

Query: 292 KRFL 295
           K+ L
Sbjct: 329 KKVL 332


>gi|222418558 methylenetetrahydrofolate dehydrogenase 2-like [Homo
           sapiens]
          Length = 347

 Score =  190 bits (482), Expect = 6e-48
 Identities = 118/302 (39%), Positives = 171/302 (56%), Gaps = 16/302 (5%)

Query: 4   AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
           A I++G E++  I+  ++  V      +    P L+I+ VG+   S+ Y+  K++AA  +
Sbjct: 51  AIIISGTEMAKHIQKEIQRGVESWVS-LGNRRPHLSIILVGDNPASHTYVRNKIRAASAV 109

Query: 64  GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
           GI +  I  P+  ++ E++     LN D  V G LVQLPL     ++   + N IAPEKD
Sbjct: 110 GICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDH--VDERTICNGIAPEKD 167

Query: 124 VDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHD 183
           VDG   IN G+L     +   IP T     E+IK TG+   G++ VV GRSK VG P+  
Sbjct: 168 VDGFHIINIGRLCLDQHS--LIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAM 225

Query: 184 LLLWN--------NATVTTCHSKTA--HLDEEVNKGDILVVATGQPEMVKGEWIKPGAIV 233
           LL  +        +ATVT  H  T    L       DI++VA G P+++  + +K GA V
Sbjct: 226 LLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAV 285

Query: 234 IDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKR 293
           ID GINYV  D      K+VGDV ++  K++A FITPVPGGVGPMTVAML+++T+ +AK+
Sbjct: 286 IDVGINYV-HDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKK 344

Query: 294 FL 295
            +
Sbjct: 345 II 346


>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
          Length = 3639

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 18/56 (32%), Positives = 30/56 (53%)

Query: 787  HWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELL 842
            HWAE  +   A AQ +Q+A      F  + +L+  VE+K  +++ + YG D+   L
Sbjct: 1572 HWAELERACEARAQCLQQAVTFQQYFLDVSELEGWVEEKRPLVSSRDYGRDEAATL 1627


>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
          Length = 3062

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 53   INVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLN-EDSTVHGFLVQLPLDSENSINT 111
            IN+ L   E+ G K+ ++       +    KYI++ + ED   H    Q+P D E+    
Sbjct: 1959 INISLPG-EQYGQKSLNMISSNPQVQYHNDKYISNTSGEDEKTHPGFQQMPEDKEDESEI 2017

Query: 112  EEVINAIAPEKDVD 125
            EE   A+ P  D D
Sbjct: 2018 EEYSCAVTPGGDTD 2031


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score = 30.8 bits (68), Expect = 6.2
 Identities = 24/130 (18%), Positives = 54/130 (41%), Gaps = 3/130 (2%)

Query: 7   LNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIK 66
           + GK I + +    +  + QL  ++ GF P   ++ +G  +      N  ++      ++
Sbjct: 443 VGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPG-RFDMQ 501

Query: 67  ATHIKLPRTTTESEVMK-YITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVD 125
            T +  P     +E++K Y+  +  D +V   ++       +    E ++N  A +  VD
Sbjct: 502 VT-VPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVD 560

Query: 126 GLTSINAGKL 135
           G   +   +L
Sbjct: 561 GKEMVTMKEL 570


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score = 30.8 bits (68), Expect = 6.2
 Identities = 24/130 (18%), Positives = 54/130 (41%), Gaps = 3/130 (2%)

Query: 7   LNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIK 66
           + GK I + +    +  + QL  ++ GF P   ++ +G  +      N  ++      ++
Sbjct: 386 VGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPG-RFDMQ 444

Query: 67  ATHIKLPRTTTESEVMK-YITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVD 125
            T +  P     +E++K Y+  +  D +V   ++       +    E ++N  A +  VD
Sbjct: 445 VT-VPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVD 503

Query: 126 GLTSINAGKL 135
           G   +   +L
Sbjct: 504 GKEMVTMKEL 513


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 30.8 bits (68), Expect = 6.2
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 15/97 (15%)

Query: 491 DIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAP 550
           +IQ R  KR+ +  T  +T   + I+ FA L         ++ L+      + I + Q  
Sbjct: 162 EIQSRENKRMQVLLTQVSTKRQQVISEFAHL---------RKFLEEQ----QSILLAQLE 208

Query: 551 TEKGHT--RTAQFDISVASEIMAVLALTTSLEDMRER 585
           ++ G    +  +FD+ VA EI    AL   LE+  ER
Sbjct: 209 SQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNER 245


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score = 30.8 bits (68), Expect = 6.2
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 15/97 (15%)

Query: 491 DIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAP 550
           +IQ R  KR+ +  T  +T   + I+ FA L         ++ L+      + I + Q  
Sbjct: 162 EIQSRENKRMQVLLTQVSTKRQQVISEFAHL---------RKFLEEQ----QSILLAQLE 208

Query: 551 TEKGHT--RTAQFDISVASEIMAVLALTTSLEDMRER 585
           ++ G    +  +FD+ VA EI    AL   LE+  ER
Sbjct: 209 SQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNER 245


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score = 30.4 bits (67), Expect = 8.0
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 12/63 (19%)

Query: 370 KYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGY 429
           KY +  G+     G G +   +G+   +GA       A V Q  + P     GGAAGGGY
Sbjct: 134 KYSLAGGLLAAGAGGGGAAVAMGVGVGVGA-------AAVGQRLESP-----GGAAGGGY 181

Query: 430 SQV 432
           + V
Sbjct: 182 AHV 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,935,301
Number of Sequences: 37866
Number of extensions: 1602361
Number of successful extensions: 3575
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3552
Number of HSP's gapped (non-prelim): 15
length of query: 935
length of database: 18,247,518
effective HSP length: 112
effective length of query: 823
effective length of database: 14,006,526
effective search space: 11527370898
effective search space used: 11527370898
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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