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Search of human proteins with 22202611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22202611 carboxypeptidase D precursor [Homo sapiens]
(1380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 2813 0.0
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 394 e-109
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 382 e-105
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 368 e-101
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 368 e-101
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 368 e-101
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 347 5e-95
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 328 2e-89
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 320 6e-87
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 320 6e-87
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 320 6e-87
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 310 5e-84
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 74 1e-12
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 64 1e-09
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 59 4e-08
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 54 1e-06
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 52 4e-06
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 49 3e-05
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 49 3e-05
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 49 3e-05
gi|27436871 carboxypeptidase O [Homo sapiens] 49 4e-05
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 47 1e-04
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 47 1e-04
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 40 0.012
gi|190194403 ATP/GTP binding protein-like 4 [Homo sapiens] 35 0.65
gi|4759258 zinc finger, BED-type containing 1 [Homo sapiens] 34 1.1
gi|4506321 protein tyrosine phosphatase, receptor type, N precur... 33 1.4
gi|7662470 neuroligin 1 [Homo sapiens] 33 2.5
gi|62244004 modulator of estrogen induced transcription isoform ... 32 3.2
gi|63176611 modulator of estrogen induced transcription isoform ... 32 3.2
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 2813 bits (7292), Expect = 0.0
Identities = 1380/1380 (100%), Positives = 1380/1380 (100%)
Query: 1 MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYH 60
MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYH
Sbjct: 1 MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYH 60
Query: 61 EEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPD 120
EEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPD
Sbjct: 61 EEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPD 120
Query: 121 AAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLP 180
AAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLP
Sbjct: 121 AAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLP 180
Query: 181 SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRA 240
SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRA
Sbjct: 181 SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRA 240
Query: 241 LIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHP 300
LIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHP
Sbjct: 241 LIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHP 300
Query: 301 IMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPAS 360
IMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPAS
Sbjct: 301 IMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPAS 360
Query: 361 QLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFY 420
QLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFY
Sbjct: 361 QLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFY 420
Query: 421 RLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTEAVSTASTV 480
RLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTEAVSTASTV
Sbjct: 421 RLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTEAVSTASTV 480
Query: 481 AIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYV 540
AIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYV
Sbjct: 481 AIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYV 540
Query: 541 MEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRI 600
MEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRI
Sbjct: 541 MEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRI 600
Query: 601 HLMPSMNPDGYEKSQEGDSISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMK 660
HLMPSMNPDGYEKSQEGDSISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMK
Sbjct: 601 HLMPSMNPDGYEKSQEGDSISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMK 660
Query: 661 SYPFVLSANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPC 720
SYPFVLSANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPC
Sbjct: 661 SYPFVLSANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPC 720
Query: 721 KNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQ 780
KNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQ
Sbjct: 721 KNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQ 780
Query: 781 NRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTY 840
NRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTY
Sbjct: 781 NRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTY 840
Query: 841 KITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTK 900
KITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTK
Sbjct: 841 KITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTK 900
Query: 901 EFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLG 960
EFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLG
Sbjct: 901 EFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLG 960
Query: 961 QSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPA 1020
QSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPA
Sbjct: 961 QSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPA 1020
Query: 1021 VTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKIGQTNARGKDLDTDFTNNASQPETKAII 1080
VTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKIGQTNARGKDLDTDFTNNASQPETKAII
Sbjct: 1021 VTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKIGQTNARGKDLDTDFTNNASQPETKAII 1080
Query: 1081 ENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSC 1140
ENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSC
Sbjct: 1081 ENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSC 1140
Query: 1141 PNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADN 1200
PNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADN
Sbjct: 1141 PNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADN 1200
Query: 1201 KRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKEGGYFHVLLAPGVHNII 1260
KRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKEGGYFHVLLAPGVHNII
Sbjct: 1201 KRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKEGGYFHVLLAPGVHNII 1260
Query: 1261 AIADGYQQQHSQVFVHHDAASSVVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIW 1320
AIADGYQQQHSQVFVHHDAASSVVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIW
Sbjct: 1261 AIADGYQQQHSQVFVHHDAASSVVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIW 1320
Query: 1321 CICSIKSNRHKDGFHRLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH 1380
CICSIKSNRHKDGFHRLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH
Sbjct: 1321 CICSIKSNRHKDGFHRLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH 1380
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 394 bits (1011), Expect = e-109
Identities = 205/413 (49%), Positives = 266/413 (64%), Gaps = 32/413 (7%)
Query: 501 FHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYI 560
F +H +P++ L + I+R+Y++G+S E REL V+E+SDNPGVHEPGEPEFKYI
Sbjct: 51 FEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYI 110
Query: 561 GNMHGNEVVGRELLLNLIEYLCKNFGTDPE-VTDLVHNTRIHLMPSMNPDGYEK--SQEG 617
GNMHGNE VGRELL+ L +YLC + E + +L+H+TRIH+MPS+NPDG+EK SQ G
Sbjct: 111 GNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPG 170
Query: 618 DSIS-VIGRNNSNNFDLNRNFPD-----------------------QFVQITDPTQPETI 653
+ +GR+N+ DLNRNFPD + V PET
Sbjct: 171 ELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETK 230
Query: 654 AVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQGLA-TYSKSPDDAVFQQIALSYSKENS 712
AV+ W+ PFVLSANLHGG LV NYP+D+ G A YS SPDDA+FQ +A +YS N
Sbjct: 231 AVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNP 290
Query: 713 QMFQGR--PCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPL 770
M PC+ + F G TNG +WY+VPGGMQD+NYL +NCFE+T+EL C K+P
Sbjct: 291 AMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPP 350
Query: 771 EKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGD 830
E+ L +WE N+ SLI +++Q+H+GV+GFV D G I NATISV I+H VT+ K GD
Sbjct: 351 EETLKTYWEDNKNSLISYLEQIHRGVKGFVRDL-QGNPIANATISVEGIDHDVTSAKDGD 409
Query: 831 YWRLLVPGTYKITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTDSNNESKK 883
YWRLL+PG YK+TASA GY +TK V V A V+F L S ++ E K+
Sbjct: 410 YWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGVDFEL-ESFSERKEEEKE 461
Score = 315 bits (807), Expect = 2e-85
Identities = 190/477 (39%), Positives = 270/477 (56%), Gaps = 60/477 (12%)
Query: 12 RLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGA-------EAAEGQFDRYYHEEEL 64
R G LL +C G+ A + AEA A + +G Y+ EL
Sbjct: 4 RGGSALLALC----GALAACGWLLGAEAQEPGAPAAGMRRRRRLQQEDGISFEYHRYPEL 59
Query: 65 ESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGP 124
AL + ++R++++GRS EGR L V+ L+ D G
Sbjct: 60 REAL-VSVWLQCTAISRIYTVGRSFEGRELLVIELS-------------------DNPGV 99
Query: 125 LLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNP 184
PG P+ K +GNMHG+E V R++LI+LA+ L Y++G+ +V L+++T ++++PSLNP
Sbjct: 100 HEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNP 159
Query: 185 DGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPD-------QFSTGEP-------- 229
DGFE+A D GR N++G DLNR+FPD G P
Sbjct: 160 DGFEKAASQPGELKDW----FVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNM 215
Query: 230 -PALDE----VPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSD 284
+D+ PE +A+I WI FVLS NLHGG +VA+YP+D++ A YS + D
Sbjct: 216 KKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHE-YSSSPD 274
Query: 285 DEVFKYLAKAYASNHPIMKT-GEPHC-PGDEDETFKDGITNGAHWYDVEGGMQDYNYVWA 342
D +F+ LA+AY+S +P M P C D+D +F DG TNG WY V GGMQD+NY+ +
Sbjct: 275 DAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSS 334
Query: 343 NCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATI 402
NCFEIT+ELSC K+PP L+ WE+N+ SLI+ +E++H GVKGFV+D + G+ + NATI
Sbjct: 335 NCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRD-LQGNPIANATI 393
Query: 403 SVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSL 459
SV GI+H++T+ + GD++RLL+PG Y LT GY+ +T V V PA VDF L
Sbjct: 394 SVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAIT-KKVAVPYSPAAGVDFEL 449
Score = 211 bits (537), Expect = 4e-54
Identities = 138/398 (34%), Positives = 204/398 (51%), Gaps = 48/398 (12%)
Query: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
+ YH Y +L E L + + I+ + +G+S E R + +E+S+ P V EP EP+ +++
Sbjct: 51 FEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYI 110
Query: 991 AGIHGNAPVGTELLLALAEFLCLNYKK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDC 1049
+HGN VG ELL+ LA++LC Y+K N + L+ TRI I+PSLNPDG E+A +
Sbjct: 111 GNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPG 170
Query: 1050 TSK---IGQTNARGKDLDTDF-----------------------------TNNASQPETK 1077
K +G++NA+G DL+ +F N PETK
Sbjct: 171 ELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETK 230
Query: 1078 AIIENLIQKQDFSLSVALDGGSMLVTYPYDK-------PVQTVENKETLKHLASLYANNH 1130
A+I + I F LS L GG ++ YPYD+ + + + LA Y++ +
Sbjct: 231 AVI-HWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFN 289
Query: 1131 PSM-HMGQPSC-PNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFP 1188
P+M +P C N D + G G W+S G M+D++ +C EITV SC FP
Sbjct: 290 PAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFP 349
Query: 1189 SAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIK---VQTKEG 1245
L + W DNK SL+S L ++H+GV GFV+D G PI+ A I + EGI K+G
Sbjct: 350 PEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISV-EGIDHDVTSAKDG 408
Query: 1246 GYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSV 1283
Y+ LL PG + + A A GY +V V + A+ V
Sbjct: 409 DYWR-LLIPGNYKLTASAPGYLAITKKVAVPYSPAAGV 445
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 382 bits (982), Expect = e-105
Identities = 200/410 (48%), Positives = 265/410 (64%), Gaps = 35/410 (8%)
Query: 493 YQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEP 552
++ + P F HH + D+ L + NE P ITR+YS+G+SVE R LYV+E SD+PG+HEP
Sbjct: 15 FKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEP 74
Query: 553 GEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNF-GTDPEVTDLVHNTRIHLMPSMNPDGY 611
EPE KY+GNMHGNE +GREL+L L E+LC+ F + + L+ +TRIH++PSMNPDGY
Sbjct: 75 LEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGY 134
Query: 612 E-KSQEGDSIS--VIGRNNSNNFDLNRNFPDQFVQI-------------------TDPTQ 649
E + +G + ++GRNN+N DLNRNFPD I +
Sbjct: 135 EVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVE 194
Query: 650 PETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQ------GLATYSKSPDDAVFQQI 703
PET AV+ WM S+ FVLSANLHGG++V NYP+D + + +PDD +FQ++
Sbjct: 195 PETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKL 254
Query: 704 ALSYSKENSQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIEL 763
A YS + MFQG C +YFP GITNGASWY++ GMQD+NYL TNCFE+T+EL
Sbjct: 255 AKVYSYAHGWMFQGWNC-----GDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLEL 309
Query: 764 GCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPV 823
C K+P E+EL W NR +LIQF++QVHQG++G VLD + + NA ISV+ INH V
Sbjct: 310 SCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLD-ENYNNLANAVISVSGINHDV 368
Query: 824 TTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSEGAIQVNFTLVRS 873
T+ GDY+RLL+PG Y ++A+A GY+P T VTV VNF L RS
Sbjct: 369 TSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRS 418
Score = 307 bits (787), Expect = 4e-83
Identities = 179/412 (43%), Positives = 244/412 (59%), Gaps = 50/412 (12%)
Query: 77 PGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVG 136
PG+ R++SIGRSVEGR L+VL + D G P P+VK VG
Sbjct: 43 PGITRVYSIGRSVEGRHLYVLEFS-------------------DHPGIHEPLEPEVKYVG 83
Query: 137 NMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCG 196
NMHG+E + R++++ L+ L +R + R+V+L+ T +++LPS+NPDG+E A
Sbjct: 84 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVA----AA 139
Query: 197 FGDGGPSGASGRDNSRGRDLNRSFPD-------QFSTGEP----PALDE-----VPEVRA 240
G P GR+N+ G DLNR+FPD G P P D PE RA
Sbjct: 140 QGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRA 199
Query: 241 LIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIY----SKTSDDEVFKYLAKAYA 296
+I W+ FVLS NLHGG+VVA+YP+D S EH+ G+ + T DD++F+ LAK Y+
Sbjct: 200 VIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYS 259
Query: 297 SNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKY 356
H M G +C + F DGITNGA WY + GMQD+NY+ NCFEITLELSC K+
Sbjct: 260 YAHGWMFQGW-NC----GDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 314
Query: 357 PPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRF 416
PP +L++EW NRE+LI +E+VH G+KG V D + L NA ISV+GINH++T+G
Sbjct: 315 PPEEELQREWLGNREALIQFLEQVHQGIKGMVLDE-NYNNLANAVISVSGINHDVTSGDH 373
Query: 417 GDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIP 468
GD++RLL+PG Y ++ GY P TVT V V T V+F L+ ++ V P
Sbjct: 374 GDYFRLLLPGIYTVSATAPGYDPETVT-VTVGPAEPTLVNFHLKRSIPQVSP 424
Score = 194 bits (494), Expect = 4e-49
Identities = 124/393 (31%), Positives = 199/393 (50%), Gaps = 50/393 (12%)
Query: 926 LALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEP 985
+A +R+H Y DL L + P IT + ++G+S E RH++ LE S+ P + EP EP
Sbjct: 18 VAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEP 77
Query: 986 KIRFVAGIHGNAPVGTELLLALAEFLCLNYK-KNPAVTQLVDRTRIVIVPSLNPDGRERA 1044
++++V +HGN +G EL+L L+EFLC ++ +N + QL+ TRI I+PS+NPDG E A
Sbjct: 78 EVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVA 137
Query: 1045 QEKDCTSK---IGQTNARGKDLDTDFTN-------------------------NASQPET 1076
+ +G+ NA G DL+ +F + + +PET
Sbjct: 138 AAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPET 197
Query: 1077 KAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQ------------TVENKETLKHLAS 1124
+A+I + +F LS L GG+++ YPYDK + + + + LA
Sbjct: 198 RAVI-RWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAK 256
Query: 1125 LYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSC 1184
+Y+ H M G + P G+ GA W+S M+D++ + +C EIT+ SC
Sbjct: 257 VYSYAHGWMFQGW-----NCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSC 311
Query: 1185 CYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIK--VQT 1242
FP L W N+ +L+ L +VH+G+ G V D+ ++ AVI ++ GI V +
Sbjct: 312 DKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVS-GINHDVTS 370
Query: 1243 KEGGYFHVLLAPGVHNIIAIADGYQQQHSQVFV 1275
+ G + LL PG++ + A A GY + V V
Sbjct: 371 GDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 368 bits (945), Expect = e-101
Identities = 184/361 (50%), Positives = 248/361 (68%), Gaps = 10/361 (2%)
Query: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
DF++H ME FL+ A Y ++T L+S+GKSV+ R L+V+ + P H G PEFKY
Sbjct: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
Query: 560 IGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDS 619
+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+++TRIH+MPSMNPDG+E ++ D
Sbjct: 79 VANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
Query: 620 ISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNY 679
IGR N N +DLNRNFPD F QPET+AVM W+K+ FVLSANLHGG+LV +Y
Sbjct: 139 YYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASY 198
Query: 680 PFDDDEQGL-ATYSKS--PDDAVFQQIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNG 736
PFD+ Q A YS+S PDD VFQ +A +Y+ N M +G CKN FP+G+TNG
Sbjct: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMN---FPNGVTNG 255
Query: 737 ASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGV 796
SWY + GGMQD+NY+ CFE+T+EL C KYP E++LP+FW N+ SLI+++KQVH GV
Sbjct: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
Query: 797 RGFVLDATDGRGILNATISVAEINH--PVTTYKTGDYWRLLVPGTYKITASARGYNP-VT 853
+G V D +G + N + V + H P T K G+Y+ LL+PG+Y I + G++P +T
Sbjct: 316 KGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHIT 374
Query: 854 K 854
K
Sbjct: 375 K 375
Score = 294 bits (753), Expect = 3e-79
Identities = 170/399 (42%), Positives = 237/399 (59%), Gaps = 42/399 (10%)
Query: 56 DRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPD 115
D YH +E A + A + L SIG+SV+GR LWVL +G E
Sbjct: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL----VVGRFPKEHRI--- 71
Query: 116 AAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTD 175
G P+ K V NMHGDETV R++L++L L + DP + L+N+T
Sbjct: 72 ------------GIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTR 118
Query: 176 VYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEV 235
++++PS+NPDGFE ++ DC + + GR+N DLNR+FPD F E +
Sbjct: 119 IHIMPSMNPDGFEAVKKPDCYY-------SIGRENYNQYDLNRNFPDAF---EYNNVSRQ 168
Query: 236 PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATG-IYSK--TSDDEVFKYLA 292
PE A+++W++ FVLS NLHGG++VASYPFD+ + ATG +YS+ T DD+VF+YLA
Sbjct: 169 PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ--ATGALYSRSLTPDDDVFQYLA 226
Query: 293 KAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELS 352
YAS +P MK G+ C + F +G+TNG WY ++GGMQDYNY+WA CFEITLELS
Sbjct: 227 HTYASRNPNMKKGD-ECKNKMN--FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 353 CCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINH--N 410
CCKYP +L W NN+ SLI I++VH+GVKG V D G+ L N + V H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICP 342
Query: 411 ITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKE 449
T ++G++Y LL+PG+Y + V + G+ P +T V++ E
Sbjct: 343 YRTNKYGEYYLLLLPGSYIINVTVPGHDP-HITKVIIPE 380
Score = 223 bits (569), Expect = 8e-58
Identities = 123/363 (33%), Positives = 202/363 (55%), Gaps = 22/363 (6%)
Query: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
+ YH + + FL+ + NY +T+L ++G+S + R++W L + P P+ ++V
Sbjct: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
Query: 991 AGIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCT 1050
A +HG+ VG ELLL L ++L + K+P +T L++ TRI I+PS+NPDG E ++ DC
Sbjct: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
Query: 1051 SKIGQTNARGKDLDTDFT-----NNAS-QPETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104
IG+ N DL+ +F NN S QPET A+++ ++ + F LS L GG+++ +Y
Sbjct: 140 YSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMK-WLKTETFVLSANLHGGALVASY 198
Query: 1105 PYDKPVQT---------VENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRG 1155
P+D VQ + + ++LA YA+ +P+M G C NK N P GV G
Sbjct: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD-ECKNKM--NFPNGVTNG 255
Query: 1156 AEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGV 1215
W+ G M+DY+ + C EIT+ SCC +P +LPS W +NK SL+ + +VH GV
Sbjct: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
Query: 1216 HGFVKDKTGKPISKAVIVLNEGIKV---QTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272
G V D+ G P+ ++ + + + +T + G +++LL PG + I G+ ++
Sbjct: 316 KGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITK 375
Query: 1273 VFV 1275
V +
Sbjct: 376 VII 378
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 368 bits (945), Expect = e-101
Identities = 184/361 (50%), Positives = 248/361 (68%), Gaps = 10/361 (2%)
Query: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
DF++H ME FL+ A Y ++T L+S+GKSV+ R L+V+ + P H G PEFKY
Sbjct: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
Query: 560 IGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDS 619
+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+++TRIH+MPSMNPDG+E ++ D
Sbjct: 79 VANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
Query: 620 ISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNY 679
IGR N N +DLNRNFPD F QPET+AVM W+K+ FVLSANLHGG+LV +Y
Sbjct: 139 YYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASY 198
Query: 680 PFDDDEQGL-ATYSKS--PDDAVFQQIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNG 736
PFD+ Q A YS+S PDD VFQ +A +Y+ N M +G CKN FP+G+TNG
Sbjct: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMN---FPNGVTNG 255
Query: 737 ASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGV 796
SWY + GGMQD+NY+ CFE+T+EL C KYP E++LP+FW N+ SLI+++KQVH GV
Sbjct: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
Query: 797 RGFVLDATDGRGILNATISVAEINH--PVTTYKTGDYWRLLVPGTYKITASARGYNP-VT 853
+G V D +G + N + V + H P T K G+Y+ LL+PG+Y I + G++P +T
Sbjct: 316 KGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHIT 374
Query: 854 K 854
K
Sbjct: 375 K 375
Score = 294 bits (753), Expect = 3e-79
Identities = 170/399 (42%), Positives = 237/399 (59%), Gaps = 42/399 (10%)
Query: 56 DRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPD 115
D YH +E A + A + L SIG+SV+GR LWVL +G E
Sbjct: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL----VVGRFPKEHRI--- 71
Query: 116 AAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTD 175
G P+ K V NMHGDETV R++L++L L + DP + L+N+T
Sbjct: 72 ------------GIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTR 118
Query: 176 VYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEV 235
++++PS+NPDGFE ++ DC + + GR+N DLNR+FPD F E +
Sbjct: 119 IHIMPSMNPDGFEAVKKPDCYY-------SIGRENYNQYDLNRNFPDAF---EYNNVSRQ 168
Query: 236 PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATG-IYSK--TSDDEVFKYLA 292
PE A+++W++ FVLS NLHGG++VASYPFD+ + ATG +YS+ T DD+VF+YLA
Sbjct: 169 PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ--ATGALYSRSLTPDDDVFQYLA 226
Query: 293 KAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELS 352
YAS +P MK G+ C + F +G+TNG WY ++GGMQDYNY+WA CFEITLELS
Sbjct: 227 HTYASRNPNMKKGD-ECKNKMN--FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 353 CCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINH--N 410
CCKYP +L W NN+ SLI I++VH+GVKG V D G+ L N + V H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICP 342
Query: 411 ITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKE 449
T ++G++Y LL+PG+Y + V + G+ P +T V++ E
Sbjct: 343 YRTNKYGEYYLLLLPGSYIINVTVPGHDP-HITKVIIPE 380
Score = 223 bits (569), Expect = 8e-58
Identities = 123/363 (33%), Positives = 202/363 (55%), Gaps = 22/363 (6%)
Query: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
+ YH + + FL+ + NY +T+L ++G+S + R++W L + P P+ ++V
Sbjct: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
Query: 991 AGIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCT 1050
A +HG+ VG ELLL L ++L + K+P +T L++ TRI I+PS+NPDG E ++ DC
Sbjct: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
Query: 1051 SKIGQTNARGKDLDTDFT-----NNAS-QPETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104
IG+ N DL+ +F NN S QPET A+++ ++ + F LS L GG+++ +Y
Sbjct: 140 YSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMK-WLKTETFVLSANLHGGALVASY 198
Query: 1105 PYDKPVQT---------VENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRG 1155
P+D VQ + + ++LA YA+ +P+M G C NK N P GV G
Sbjct: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD-ECKNKM--NFPNGVTNG 255
Query: 1156 AEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGV 1215
W+ G M+DY+ + C EIT+ SCC +P +LPS W +NK SL+ + +VH GV
Sbjct: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
Query: 1216 HGFVKDKTGKPISKAVIVLNEGIKV---QTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272
G V D+ G P+ ++ + + + +T + G +++LL PG + I G+ ++
Sbjct: 316 KGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITK 375
Query: 1273 VFV 1275
V +
Sbjct: 376 VII 378
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 368 bits (945), Expect = e-101
Identities = 184/361 (50%), Positives = 248/361 (68%), Gaps = 10/361 (2%)
Query: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
DF++H ME FL+ A Y ++T L+S+GKSV+ R L+V+ + P H G PEFKY
Sbjct: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
Query: 560 IGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDS 619
+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+++TRIH+MPSMNPDG+E ++ D
Sbjct: 79 VANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
Query: 620 ISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNY 679
IGR N N +DLNRNFPD F QPET+AVM W+K+ FVLSANLHGG+LV +Y
Sbjct: 139 YYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASY 198
Query: 680 PFDDDEQGL-ATYSKS--PDDAVFQQIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNG 736
PFD+ Q A YS+S PDD VFQ +A +Y+ N M +G CKN FP+G+TNG
Sbjct: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMN---FPNGVTNG 255
Query: 737 ASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGV 796
SWY + GGMQD+NY+ CFE+T+EL C KYP E++LP+FW N+ SLI+++KQVH GV
Sbjct: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
Query: 797 RGFVLDATDGRGILNATISVAEINH--PVTTYKTGDYWRLLVPGTYKITASARGYNP-VT 853
+G V D +G + N + V + H P T K G+Y+ LL+PG+Y I + G++P +T
Sbjct: 316 KGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHIT 374
Query: 854 K 854
K
Sbjct: 375 K 375
Score = 294 bits (753), Expect = 3e-79
Identities = 170/399 (42%), Positives = 237/399 (59%), Gaps = 42/399 (10%)
Query: 56 DRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPD 115
D YH +E A + A + L SIG+SV+GR LWVL +G E
Sbjct: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL----VVGRFPKEHRI--- 71
Query: 116 AAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTD 175
G P+ K V NMHGDETV R++L++L L + DP + L+N+T
Sbjct: 72 ------------GIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTR 118
Query: 176 VYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEV 235
++++PS+NPDGFE ++ DC + + GR+N DLNR+FPD F E +
Sbjct: 119 IHIMPSMNPDGFEAVKKPDCYY-------SIGRENYNQYDLNRNFPDAF---EYNNVSRQ 168
Query: 236 PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATG-IYSK--TSDDEVFKYLA 292
PE A+++W++ FVLS NLHGG++VASYPFD+ + ATG +YS+ T DD+VF+YLA
Sbjct: 169 PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ--ATGALYSRSLTPDDDVFQYLA 226
Query: 293 KAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELS 352
YAS +P MK G+ C + F +G+TNG WY ++GGMQDYNY+WA CFEITLELS
Sbjct: 227 HTYASRNPNMKKGD-ECKNKMN--FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 353 CCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINH--N 410
CCKYP +L W NN+ SLI I++VH+GVKG V D G+ L N + V H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICP 342
Query: 411 ITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKE 449
T ++G++Y LL+PG+Y + V + G+ P +T V++ E
Sbjct: 343 YRTNKYGEYYLLLLPGSYIINVTVPGHDP-HITKVIIPE 380
Score = 223 bits (569), Expect = 8e-58
Identities = 123/363 (33%), Positives = 202/363 (55%), Gaps = 22/363 (6%)
Query: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
+ YH + + FL+ + NY +T+L ++G+S + R++W L + P P+ ++V
Sbjct: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
Query: 991 AGIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCT 1050
A +HG+ VG ELLL L ++L + K+P +T L++ TRI I+PS+NPDG E ++ DC
Sbjct: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
Query: 1051 SKIGQTNARGKDLDTDFT-----NNAS-QPETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104
IG+ N DL+ +F NN S QPET A+++ ++ + F LS L GG+++ +Y
Sbjct: 140 YSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMK-WLKTETFVLSANLHGGALVASY 198
Query: 1105 PYDKPVQT---------VENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRG 1155
P+D VQ + + ++LA YA+ +P+M G C NK N P GV G
Sbjct: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD-ECKNKM--NFPNGVTNG 255
Query: 1156 AEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGV 1215
W+ G M+DY+ + C EIT+ SCC +P +LPS W +NK SL+ + +VH GV
Sbjct: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
Query: 1216 HGFVKDKTGKPISKAVIVLNEGIKV---QTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272
G V D+ G P+ ++ + + + +T + G +++LL PG + I G+ ++
Sbjct: 316 KGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITK 375
Query: 1273 VFV 1275
V +
Sbjct: 376 VII 378
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 347 bits (890), Expect = 5e-95
Identities = 197/434 (45%), Positives = 255/434 (58%), Gaps = 40/434 (9%)
Query: 477 ASTVAIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESR 536
A V+ PN L + + P DF HH++ M +++ + PNITR+YS+GKS +
Sbjct: 273 ACPVSDPNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGL 332
Query: 537 ELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNF-GTDPEVTDLV 595
+LYVME+SD PG HE GEPE +Y+ MHGNE +GRELLL L+++LC F +P VT L+
Sbjct: 333 KLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLL 392
Query: 596 HNTRIHLMPSMNPDGYEKSQEGDSISV---IGRNNSNNFDLNRNFPDQFVQITD------ 646
RIHL+PSMNPDGYE + S V GR N+ + DLN NF D + +
Sbjct: 393 SEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGK 452
Query: 647 ------------PTQ---------PETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDE 685
PT PET AV+ WMK PFVLSANLHGG LVV+YPFD
Sbjct: 453 VPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTR 512
Query: 686 QGLAT--YSKSPDDAVFQQIALSYSKENSQM--FQGRPCKNMYPNEYFPHG-ITNGASWY 740
A + +PDDAVF+ ++ Y+ N M RPC + ++ HG I NGA W+
Sbjct: 513 TPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPC---HSQDFSVHGNIINGADWH 569
Query: 741 NVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFV 800
VPG M D++YL TNCFEVT+EL C K+P E ELP WE N+ +L+ +++QV G+ G V
Sbjct: 570 TVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVV 629
Query: 801 LDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVK- 859
D GI +A I+V INH VTT GDYWRLL PG Y +TASA GY+ VT+N V
Sbjct: 630 RDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTF 689
Query: 860 SEGAIQVNFTLVRS 873
EG NF L ++
Sbjct: 690 EEGPFPCNFVLTKT 703
Score = 262 bits (670), Expect = 1e-69
Identities = 153/431 (35%), Positives = 231/431 (53%), Gaps = 48/431 (11%)
Query: 46 AGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGS 105
A A + D +H + L + P + R++SIG+S +G L+V+ ++
Sbjct: 286 APASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMS----- 340
Query: 106 LIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDP 165
D G G P+V+ V MHG+E + R++L+ L + L + RG+P
Sbjct: 341 --------------DKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNP 386
Query: 166 RLVRLLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFS 225
R+ RLL+ ++LLPS+NPDG+E A G A GR N++ DLN +F D +
Sbjct: 387 RVTRLLSEMRIHLLPSMNPDGYEIAYHR----GSELVGWAEGRWNNQSIDLNHNFADLNT 442
Query: 226 T-------GEPPAL-----------------DEVPEVRALIEWIRRNKFVLSGNLHGGSV 261
G+ P + PE RA+I+W++R FVLS NLHGG +
Sbjct: 443 PLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGEL 502
Query: 262 VASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGI 321
V SYPFD + A + T DD VF++L+ YA ++ M+ +D + I
Sbjct: 503 VVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNI 562
Query: 322 TNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVH 381
NGA W+ V G M D++Y+ NCFE+T+ELSC K+P ++L QEWENN+++L+T +E+V
Sbjct: 563 INGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVR 622
Query: 382 IGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLT 441
+G+ G V+D T G+ +A I+V GINH++TT GD++RLL PG Y +T GY +T
Sbjct: 623 MGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVT 682
Query: 442 VT-NVVVKEGP 451
V +EGP
Sbjct: 683 RNCRVTFEEGP 693
Score = 190 bits (482), Expect = 9e-48
Identities = 121/385 (31%), Positives = 204/385 (52%), Gaps = 52/385 (13%)
Query: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
+++H+YK + + ++ + P+IT + ++G+S + ++ +E+S+KP E EP++R+V
Sbjct: 297 FQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYV 356
Query: 991 AGIHGNAPVGTELLLALAEFLCLNYKK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDC 1049
AG+HGN +G ELLL L +FLC + + NP VT+L+ RI ++PS+NPDG E A +
Sbjct: 357 AGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRG- 415
Query: 1050 TSKIGQTNARGKDLDTDFTNNASQ------------------------------------ 1073
+ +G R + D +N +
Sbjct: 416 SELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATV 475
Query: 1074 -PETKAIIENLIQKQDFSLSVALDGGSMLVTYPYD--------KPVQTVENKETLKHLAS 1124
PET+A+I+ +++ F LS L GG ++V+YP+D + + + + L++
Sbjct: 476 APETRAVIK-WMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLST 534
Query: 1125 LYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSC 1184
+YA ++ +M + D ++ G ++ GA+WH+ GSM D+S + +C E+TV SC
Sbjct: 535 VYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSC 594
Query: 1185 CYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDK-TGKPISKAVIVLNEGIK--VQ 1241
FP LP W +NK +LL+ L +V G+ G V+DK T I+ AVI + +GI V
Sbjct: 595 DKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAV-DGINHDVT 653
Query: 1242 TKEGGYFHVLLAPGVHNIIAIADGY 1266
T GG + LL PG + + A A+GY
Sbjct: 654 TAWGGDYWRLLTPGDYMVTASAEGY 678
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 328 bits (841), Expect = 2e-89
Identities = 180/411 (43%), Positives = 245/411 (59%), Gaps = 39/411 (9%)
Query: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
DF HH++ +M ++ PNITR+Y++GKS + +LY +EISD+PG HE GEPEF Y
Sbjct: 315 DFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHY 374
Query: 560 IGNMHGNEVVGRELLLNLIEYLCKNF-GTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGD 618
I HGNEV+GRELLL L++++C+ + + + LV TRIH++PS+NPDGYEK+ EG
Sbjct: 375 IAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGG 434
Query: 619 SIS---VIGRNNSNNFDLNRNFPD---------------------------QFVQITDPT 648
S +GR + D+N NFPD F+
Sbjct: 435 SELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATV 494
Query: 649 QPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQGLAT--YSKSPDDAVFQQIALS 706
ET AV++WM+ PFVL NL GG LVV YP+D T ++ +PDD VF+ +A S
Sbjct: 495 AAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYS 554
Query: 707 YSKENSQMFQGRPCKNMYPNEYF--PHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELG 764
Y+ + M R + + E F G NGASW+ V G + D++YL TNCFE++I +G
Sbjct: 555 YASTHRLMTDAR--RRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
Query: 765 CVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVT 824
C KYP E +LP WE NR SLI FM+QVH+G++G V D + G+GI NA ISV INH +
Sbjct: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRD-SHGKGIPNAIISVEGINHDIR 671
Query: 825 TYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSE-GAIQVNFTLVRSS 874
T GDYWRLL PG Y +TA A G+ TKN V + GA + +FTL +++
Sbjct: 672 TANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKTN 722
Score = 253 bits (645), Expect = 1e-66
Identities = 150/420 (35%), Positives = 220/420 (52%), Gaps = 48/420 (11%)
Query: 77 PGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVG 136
P + R+++IG+S +G L+ + ++ D G G P+ +
Sbjct: 336 PNITRIYNIGKSHQGLKLYAVEIS-------------------DHPGEHEVGEPEFHYIA 376
Query: 137 NMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCG 196
HG+E + R++L+ L + + Y + R+V L+ T +++LPSLNPDG+E+A EG
Sbjct: 377 GAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGSE 436
Query: 197 FGDGGPSGASGRDNSRGRDLNRSFPDQFST-GEPPALDEVP------------------- 236
G + GR G D+N +FPD + E VP
Sbjct: 437 LG----GWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENA 492
Query: 237 ----EVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLA 292
E RA+I W+ + FVL GNL GG +V +YP+D T ++ T DD VF++LA
Sbjct: 493 TVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLA 552
Query: 293 KAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELS 352
+YAS H +M ED ++G NGA W+ V G + D++Y+ NCFE+++ +
Sbjct: 553 YSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
Query: 353 CCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNIT 412
C KYP SQL +EWENNRESLI +E+VH G+KG V+DS G G+ NA ISV GINH+I
Sbjct: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDS-HGKGIPNAIISVEGINHDIR 671
Query: 413 TGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTE 472
T GD++RLL PG Y +T G+ T +V + AT DF+L T + I + E
Sbjct: 672 TANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKTNMARIREIME 731
Score = 195 bits (496), Expect = 2e-49
Identities = 122/399 (30%), Positives = 203/399 (50%), Gaps = 49/399 (12%)
Query: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
+++H+YK++ + ++ + P+IT + N+G+S + ++++EIS+ P E EP+ ++
Sbjct: 316 FKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYI 375
Query: 991 AGIHGNAPVGTELLLALAEFLCLNY-KKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDC 1049
AG HGN +G ELLL L +F+C Y +N + LV+ TRI ++PSLNPDG E+A E
Sbjct: 376 AGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGS 435
Query: 1050 TS---KIGQTNARGKDLDTDFT---------------------------------NNASQ 1073
+G+ G D++ +F N
Sbjct: 436 ELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATVA 495
Query: 1074 PETKAIIENLIQKQDFSLSVALDGGSMLVTYPYD---KPVQTVENKET-----LKHLASL 1125
ET+A+I ++K F L L GG ++V YPYD P +T E+ T + LA
Sbjct: 496 AETRAVIA-WMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYS 554
Query: 1126 YANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCC 1185
YA+ H M + + D G + GA WH+ GS+ D+S + +C E+++Y C
Sbjct: 555 YASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCD 614
Query: 1186 YFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIK--VQTK 1243
+P ++LP W +N+ SL+ + +VH+G+ G V+D GK I A+I + EGI ++T
Sbjct: 615 KYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISV-EGINHDIRTA 673
Query: 1244 EGGYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASS 1282
G + LL PG + + A A+G+ V +D ++
Sbjct: 674 NDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGAT 712
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 320 bits (820), Expect = 6e-87
Identities = 175/400 (43%), Positives = 243/400 (60%), Gaps = 33/400 (8%)
Query: 501 FHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYI 560
F HH + M LRR A+ ++ R YS+G+S + REL V+E S PG HE EPE K I
Sbjct: 48 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 107
Query: 561 GNMHGNEVVGRELLLNLIEYLCKNFGT-DPEVTDLVHNTRIHLMPSMNPDGYE-KSQEGD 618
GN+HGNEV GRE+L+ L +YLC + +P + L++ TRIHL+PSMNPDGYE + EG
Sbjct: 108 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 167
Query: 619 SIS--VIGRNNSNNFDLNRNFPD---QFVQITDP------------------TQPETIAV 655
+ GR N+ N DLNRNFPD ++ ++ + PET A+
Sbjct: 168 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 227
Query: 656 MSWMKSYPFVLSANLHGGSLVVNYPFDDDE--QGLATYSKSPDDAVFQQIALSYSKENSQ 713
M WM++ PFVLSA+LHGG LVV+YPFD + Q +S +PD+ +F+ ++ +Y+ +
Sbjct: 228 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPM 287
Query: 714 MFQGRPCKNMYPNEYFPHG-ITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEK 772
M +N + G I NGA WY+ GGM D+NYL TNCFE+T+ELGCVK+P E+
Sbjct: 288 MMDRS--ENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEE 345
Query: 773 ELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYW 832
L W+ N+ SL+ F++ VH+G++G V D G+ + NA ISV I H +TT GDYW
Sbjct: 346 ALYTLWQHNKESLLNFVETVHRGIKGVVTDKF-GKPVKNARISVKGIRHDITTAPDGDYW 404
Query: 833 RLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870
RLL PG + + A A GY V K V + + + A +V+F L
Sbjct: 405 RLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFIL 444
Score = 280 bits (717), Expect = 5e-75
Identities = 170/431 (39%), Positives = 241/431 (55%), Gaps = 53/431 (12%)
Query: 55 FDRYYHEE--ELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDA 112
F R+ H ++ LR A+ +AR +SIGRS +GR L V+ ++ G
Sbjct: 45 FIRFSHHSYAQMVRVLRRTASR-CAHVARTYSIGRSFDGRELLVIEFSSRPGQ------- 96
Query: 113 GPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLN 172
L+ P+VKL+GN+HG+E R++LIYLA+ L + Y G+PR+ RLLN
Sbjct: 97 ----------HELM--EPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLN 144
Query: 173 TTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPAL 232
TT ++LLPS+NPDG+E A G+ SGR N++ DLNR+FPD T E L
Sbjct: 145 TTRIHLLPSMNPDGYEVAAAEGAGYN----GWTSGRQNAQNLDLNRNFPDL--TSEYYRL 198
Query: 233 DEV--------------------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPE 272
E PE +A+++W++ FVLS +LHGG +V SYPFD S
Sbjct: 199 AETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKH 258
Query: 273 HKATGIYSKTSDDEVFKYLAKAYASNHPIMKT-GEPHCPGDEDETFKDGITNGAHWYDVE 331
+ ++S T D+++FK L++AYA HP+M E C G+ + + I NGA WY
Sbjct: 259 PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLK--RGSIINGADWYSFT 316
Query: 332 GGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDS 391
GGM D+NY+ NCFEIT+EL C K+PP L W++N+ESL+ +E VH G+KG V D
Sbjct: 317 GGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDK 376
Query: 392 ITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVV-VKEG 450
G ++NA ISV GI H+ITT GD++RLL PG + + GY + ++ +
Sbjct: 377 F-GKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMK 435
Query: 451 PATEVDFSLRP 461
A VDF L+P
Sbjct: 436 RAGRVDFILQP 446
Score = 197 bits (502), Expect = 4e-50
Identities = 135/423 (31%), Positives = 209/423 (49%), Gaps = 57/423 (13%)
Query: 896 DPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITN 955
DP K L D + +GL +R S +HSY + LR H+
Sbjct: 22 DPLEKLRGGLEADEALPSGLPPTFIRFS---------HHSYAQMVRVLRRTASRCAHVAR 72
Query: 956 LTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNY 1015
++G+S + R + +E S++P E EP+++ + IHGN G E+L+ LA++LC Y
Sbjct: 73 TYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEY 132
Query: 1016 KK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSK---IGQTNARGKDLDTDFTNNA 1071
NP + +L++ TRI ++PS+NPDG E A + G+ NA+ DL+ +F +
Sbjct: 133 LLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLT 192
Query: 1072 SQ---------------------------PETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104
S+ PETKAI++ +Q F LS +L GG ++V+Y
Sbjct: 193 SEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMK-WMQTIPFVLSASLHGGDLVVSY 251
Query: 1105 PYD--------KPVQTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENI--PGGVMR 1154
P+D K +++ K L+ YA+ HP M N+ N G ++
Sbjct: 252 PFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMM---MDRSENRCGGNFLKRGSIIN 308
Query: 1155 GAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKG 1214
GA+W+S G M D++ + +C EITV C FP L +LW NK SLL+ + VH+G
Sbjct: 309 GADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRG 368
Query: 1215 VHGFVKDKTGKPISKAVIVLNEGIK--VQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272
+ G V DK GKP+ A I + +GI+ + T G + LL PG+H +IA A GY + +
Sbjct: 369 IKGVVTDKFGKPVKNARISV-KGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKK 427
Query: 1273 VFV 1275
V +
Sbjct: 428 VII 430
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 320 bits (820), Expect = 6e-87
Identities = 175/400 (43%), Positives = 243/400 (60%), Gaps = 33/400 (8%)
Query: 501 FHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYI 560
F HH + M LRR A+ ++ R YS+G+S + REL V+E S PG HE EPE K I
Sbjct: 174 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 233
Query: 561 GNMHGNEVVGRELLLNLIEYLCKNFGT-DPEVTDLVHNTRIHLMPSMNPDGYE-KSQEGD 618
GN+HGNEV GRE+L+ L +YLC + +P + L++ TRIHL+PSMNPDGYE + EG
Sbjct: 234 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 293
Query: 619 SIS--VIGRNNSNNFDLNRNFPD---QFVQITDP------------------TQPETIAV 655
+ GR N+ N DLNRNFPD ++ ++ + PET A+
Sbjct: 294 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 353
Query: 656 MSWMKSYPFVLSANLHGGSLVVNYPFDDDE--QGLATYSKSPDDAVFQQIALSYSKENSQ 713
M WM++ PFVLSA+LHGG LVV+YPFD + Q +S +PD+ +F+ ++ +Y+ +
Sbjct: 354 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPM 413
Query: 714 MFQGRPCKNMYPNEYFPHG-ITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEK 772
M +N + G I NGA WY+ GGM D+NYL TNCFE+T+ELGCVK+P E+
Sbjct: 414 MMDRS--ENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEE 471
Query: 773 ELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYW 832
L W+ N+ SL+ F++ VH+G++G V D G+ + NA ISV I H +TT GDYW
Sbjct: 472 ALYTLWQHNKESLLNFVETVHRGIKGVVTDKF-GKPVKNARISVKGIRHDITTAPDGDYW 530
Query: 833 RLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870
RLL PG + + A A GY V K V + + + A +V+F L
Sbjct: 531 RLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFIL 570
Score = 280 bits (717), Expect = 5e-75
Identities = 170/431 (39%), Positives = 241/431 (55%), Gaps = 53/431 (12%)
Query: 55 FDRYYHEE--ELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDA 112
F R+ H ++ LR A+ +AR +SIGRS +GR L V+ ++ G
Sbjct: 171 FIRFSHHSYAQMVRVLRRTASR-CAHVARTYSIGRSFDGRELLVIEFSSRPGQ------- 222
Query: 113 GPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLN 172
L+ P+VKL+GN+HG+E R++LIYLA+ L + Y G+PR+ RLLN
Sbjct: 223 ----------HELM--EPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLN 270
Query: 173 TTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPAL 232
TT ++LLPS+NPDG+E A G+ SGR N++ DLNR+FPD T E L
Sbjct: 271 TTRIHLLPSMNPDGYEVAAAEGAGYN----GWTSGRQNAQNLDLNRNFPDL--TSEYYRL 324
Query: 233 DEV--------------------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPE 272
E PE +A+++W++ FVLS +LHGG +V SYPFD S
Sbjct: 325 AETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKH 384
Query: 273 HKATGIYSKTSDDEVFKYLAKAYASNHPIMKT-GEPHCPGDEDETFKDGITNGAHWYDVE 331
+ ++S T D+++FK L++AYA HP+M E C G+ + + I NGA WY
Sbjct: 385 PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLK--RGSIINGADWYSFT 442
Query: 332 GGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDS 391
GGM D+NY+ NCFEIT+EL C K+PP L W++N+ESL+ +E VH G+KG V D
Sbjct: 443 GGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDK 502
Query: 392 ITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVV-VKEG 450
G ++NA ISV GI H+ITT GD++RLL PG + + GY + ++ +
Sbjct: 503 F-GKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMK 561
Query: 451 PATEVDFSLRP 461
A VDF L+P
Sbjct: 562 RAGRVDFILQP 572
Score = 197 bits (502), Expect = 4e-50
Identities = 135/423 (31%), Positives = 209/423 (49%), Gaps = 57/423 (13%)
Query: 896 DPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITN 955
DP K L D + +GL +R S +HSY + LR H+
Sbjct: 148 DPLEKLRGGLEADEALPSGLPPTFIRFS---------HHSYAQMVRVLRRTASRCAHVAR 198
Query: 956 LTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNY 1015
++G+S + R + +E S++P E EP+++ + IHGN G E+L+ LA++LC Y
Sbjct: 199 TYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEY 258
Query: 1016 KK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSK---IGQTNARGKDLDTDFTNNA 1071
NP + +L++ TRI ++PS+NPDG E A + G+ NA+ DL+ +F +
Sbjct: 259 LLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLT 318
Query: 1072 SQ---------------------------PETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104
S+ PETKAI++ +Q F LS +L GG ++V+Y
Sbjct: 319 SEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMK-WMQTIPFVLSASLHGGDLVVSY 377
Query: 1105 PYD--------KPVQTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENI--PGGVMR 1154
P+D K +++ K L+ YA+ HP M N+ N G ++
Sbjct: 378 PFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMM---MDRSENRCGGNFLKRGSIIN 434
Query: 1155 GAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKG 1214
GA+W+S G M D++ + +C EITV C FP L +LW NK SLL+ + VH+G
Sbjct: 435 GADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRG 494
Query: 1215 VHGFVKDKTGKPISKAVIVLNEGIK--VQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272
+ G V DK GKP+ A I + +GI+ + T G + LL PG+H +IA A GY + +
Sbjct: 495 IKGVVTDKFGKPVKNARISV-KGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKK 553
Query: 1273 VFV 1275
V +
Sbjct: 554 VII 556
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 320 bits (820), Expect = 6e-87
Identities = 175/400 (43%), Positives = 243/400 (60%), Gaps = 33/400 (8%)
Query: 501 FHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYI 560
F HH + M LRR A+ ++ R YS+G+S + REL V+E S PG HE EPE K I
Sbjct: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
Query: 561 GNMHGNEVVGRELLLNLIEYLCKNFGT-DPEVTDLVHNTRIHLMPSMNPDGYE-KSQEGD 618
GN+HGNEV GRE+L+ L +YLC + +P + L++ TRIHL+PSMNPDGYE + EG
Sbjct: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
Query: 619 SIS--VIGRNNSNNFDLNRNFPD---QFVQITDP------------------TQPETIAV 655
+ GR N+ N DLNRNFPD ++ ++ + PET A+
Sbjct: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 364
Query: 656 MSWMKSYPFVLSANLHGGSLVVNYPFDDDE--QGLATYSKSPDDAVFQQIALSYSKENSQ 713
M WM++ PFVLSA+LHGG LVV+YPFD + Q +S +PD+ +F+ ++ +Y+ +
Sbjct: 365 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPM 424
Query: 714 MFQGRPCKNMYPNEYFPHG-ITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEK 772
M +N + G I NGA WY+ GGM D+NYL TNCFE+T+ELGCVK+P E+
Sbjct: 425 MMDRS--ENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEE 482
Query: 773 ELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYW 832
L W+ N+ SL+ F++ VH+G++G V D G+ + NA ISV I H +TT GDYW
Sbjct: 483 ALYTLWQHNKESLLNFVETVHRGIKGVVTDKF-GKPVKNARISVKGIRHDITTAPDGDYW 541
Query: 833 RLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870
RLL PG + + A A GY V K V + + + A +V+F L
Sbjct: 542 RLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFIL 581
Score = 280 bits (717), Expect = 5e-75
Identities = 170/431 (39%), Positives = 241/431 (55%), Gaps = 53/431 (12%)
Query: 55 FDRYYHEE--ELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDA 112
F R+ H ++ LR A+ +AR +SIGRS +GR L V+ ++ G
Sbjct: 182 FIRFSHHSYAQMVRVLRRTASR-CAHVARTYSIGRSFDGRELLVIEFSSRPGQ------- 233
Query: 113 GPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLN 172
L+ P+VKL+GN+HG+E R++LIYLA+ L + Y G+PR+ RLLN
Sbjct: 234 ----------HELM--EPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLN 281
Query: 173 TTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPAL 232
TT ++LLPS+NPDG+E A G+ SGR N++ DLNR+FPD T E L
Sbjct: 282 TTRIHLLPSMNPDGYEVAAAEGAGYN----GWTSGRQNAQNLDLNRNFPDL--TSEYYRL 335
Query: 233 DEV--------------------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPE 272
E PE +A+++W++ FVLS +LHGG +V SYPFD S
Sbjct: 336 AETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKH 395
Query: 273 HKATGIYSKTSDDEVFKYLAKAYASNHPIMKT-GEPHCPGDEDETFKDGITNGAHWYDVE 331
+ ++S T D+++FK L++AYA HP+M E C G+ + + I NGA WY
Sbjct: 396 PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLK--RGSIINGADWYSFT 453
Query: 332 GGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDS 391
GGM D+NY+ NCFEIT+EL C K+PP L W++N+ESL+ +E VH G+KG V D
Sbjct: 454 GGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDK 513
Query: 392 ITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVV-VKEG 450
G ++NA ISV GI H+ITT GD++RLL PG + + GY + ++ +
Sbjct: 514 F-GKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMK 572
Query: 451 PATEVDFSLRP 461
A VDF L+P
Sbjct: 573 RAGRVDFILQP 583
Score = 197 bits (502), Expect = 4e-50
Identities = 135/423 (31%), Positives = 209/423 (49%), Gaps = 57/423 (13%)
Query: 896 DPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITN 955
DP K L D + +GL +R S +HSY + LR H+
Sbjct: 159 DPLEKLRGGLEADEALPSGLPPTFIRFS---------HHSYAQMVRVLRRTASRCAHVAR 209
Query: 956 LTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNY 1015
++G+S + R + +E S++P E EP+++ + IHGN G E+L+ LA++LC Y
Sbjct: 210 TYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEY 269
Query: 1016 KK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSK---IGQTNARGKDLDTDFTNNA 1071
NP + +L++ TRI ++PS+NPDG E A + G+ NA+ DL+ +F +
Sbjct: 270 LLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLT 329
Query: 1072 SQ---------------------------PETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104
S+ PETKAI++ +Q F LS +L GG ++V+Y
Sbjct: 330 SEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMK-WMQTIPFVLSASLHGGDLVVSY 388
Query: 1105 PYD--------KPVQTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENI--PGGVMR 1154
P+D K +++ K L+ YA+ HP M N+ N G ++
Sbjct: 389 PFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMM---MDRSENRCGGNFLKRGSIIN 445
Query: 1155 GAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKG 1214
GA+W+S G M D++ + +C EITV C FP L +LW NK SLL+ + VH+G
Sbjct: 446 GADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRG 505
Query: 1215 VHGFVKDKTGKPISKAVIVLNEGIK--VQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272
+ G V DK GKP+ A I + +GI+ + T G + LL PG+H +IA A GY + +
Sbjct: 506 IKGVVTDKFGKPVKNARISV-KGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKK 564
Query: 1273 VFV 1275
V +
Sbjct: 565 VII 567
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 310 bits (795), Expect = 5e-84
Identities = 175/430 (40%), Positives = 241/430 (56%), Gaps = 59/430 (13%)
Query: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
DF HH + DM ++ E P ITR YSLGKS ++Y MEISDNPG HE GEPEF+Y
Sbjct: 561 DFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRY 620
Query: 560 IGNMHGNEVVGRELLLNLIEYLCKNFGT-DPEVTDLVHNTRIHLMPSMNPDGYE-KSQEG 617
+HGNEV+GRELLL L++YLC+ + +P V LV +TRIHL+PS+NPDGYE +Q G
Sbjct: 621 TAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMG 680
Query: 618 DSIS--VIGRNNSNNFDLNRNFPD---------------------------QFVQITDPT 648
+G FD+ +FPD +++
Sbjct: 681 SEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATV 740
Query: 649 QPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFD--------------------DDEQGL 688
E A+++WM+ PFVL ANL+GG +V+YP+D +DE +
Sbjct: 741 STEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEV 800
Query: 689 ATYSKSPDDAVFQQIALSYSKEN---SQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGG 745
+ ++PD A+F+ +A+S++ + ++ ++G Y GI NGA W G
Sbjct: 801 SEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGM---GIVNGAKWNPRTGT 857
Query: 746 MQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATD 805
+ D++YL TNC E++ LGC K+P E ELP WE N+ +L+ FM+QVH+G++G V D
Sbjct: 858 INDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTD-EQ 916
Query: 806 GRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSE-GAI 864
G I NATISV+ INH V T GDYWR+L PG Y++TA A GY P K V + GA
Sbjct: 917 GIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
Query: 865 QVNFTLVRSS 874
Q NF L RS+
Sbjct: 977 QCNFILARSN 986
Score = 216 bits (549), Expect = 2e-55
Identities = 150/486 (30%), Positives = 226/486 (46%), Gaps = 78/486 (16%)
Query: 18 LLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLP 77
L M L +LG S + A+ T D +H + L + P
Sbjct: 531 LCMRLEVLGCSVAPVYSYYAQNEVVATD--------DLDFRHHSYKDMRQLMKVVNEECP 582
Query: 78 GLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGN 137
+ R +S+G+S G ++ + ++ D G G P+ +
Sbjct: 583 TITRTYSLGKSSRGLKIYAMEIS-------------------DNPGEHELGEPEFRYTAG 623
Query: 138 MHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGF 197
+HG+E + R++L+ L + L YR G+PR+ L+ T ++L+PSLNPDG+E A + F
Sbjct: 624 IHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEF 683
Query: 198 GDGGPSGASGRDNSRGRDLNRSFPDQFST------------------------GEPPALD 233
G+ A G G D+ FPD S P
Sbjct: 684 GNW----ALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDAT 739
Query: 234 EVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDS------------------PEHKA 275
EVRA+I W+ +N FVL NL+GG + SYP+D + +
Sbjct: 740 VSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDE 799
Query: 276 TGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPG--DEDETFKDGITNGAHWYDVEGG 333
+T D +F++LA ++AS H + EP+ G +D T GI NGA W G
Sbjct: 800 VSEAQETPDHAIFRWLAISFASAH--LTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGT 857
Query: 334 MQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSIT 393
+ D++Y+ NC E++ L C K+P S+L +EWENN+E+L+T +E+VH G+KG V D
Sbjct: 858 INDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDE-Q 916
Query: 394 GSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPAT 453
G + NATISV+GINH + T GD++R+L PG Y +T GY P T V + AT
Sbjct: 917 GIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
Query: 454 EVDFSL 459
+ +F L
Sbjct: 977 QCNFIL 982
Score = 191 bits (485), Expect = 4e-48
Identities = 135/418 (32%), Positives = 200/418 (47%), Gaps = 69/418 (16%)
Query: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
+R+HSYKD+ + ++ + P IT +LG+S+ I+++EIS+ P E EP+ R+
Sbjct: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621
Query: 991 AGIHGNAPVGTELLLALAEFLCLNYKK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDC 1049
AGIHGN +G ELLL L ++LC Y+ NP V LV TRI +VPSLNPDG E A +
Sbjct: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681
Query: 1050 ---TSKIGQTNARGKDLDTDF---------------------TNNASQP----------- 1074
+G G D+ DF NN P
Sbjct: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741
Query: 1075 -ETKAIIENLIQKQDFSLSVALDGGSMLVTYPYD---KPVQ------------------T 1112
E +AII ++K F L L+GG LV+YPYD P Q
Sbjct: 742 TEVRAIIA-WMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEV 800
Query: 1113 VENKETLKH-----LASLYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKD 1167
E +ET H LA +A+ H ++ D G++ GA+W+ G++ D
Sbjct: 801 SEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTIND 860
Query: 1168 YSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPI 1227
+S + +C E++ Y C FP + LP W +NK +LL+ + +VH+G+ G V D+ G PI
Sbjct: 861 FSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPI 920
Query: 1228 SKAVIV---LNEGIKVQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASS 1282
+ A I +N G+K T GG + +L PG + + A A+GY V +D ++
Sbjct: 921 ANATISVSGINHGVK--TASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 73.6 bits (179), Expect = 1e-12
Identities = 73/270 (27%), Positives = 116/270 (42%), Gaps = 54/270 (20%)
Query: 47 GAEAAEGQFDR-YYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGS 105
G E + F+ YH E + AA P LAR IG S E RP++VL+ + G G
Sbjct: 110 GQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG- 168
Query: 106 LIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDP 165
RP V L +H E +S+ I+ AR++ + Y+R DP
Sbjct: 169 ---------------------VRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQR-DP 206
Query: 166 RLVRLLNTTDVYLLPSLNPDGF----------ERAREGDCGFGDGGPSGASGRDNSRGRD 215
+ +L D++LLP NPDG+ + R + G S G D + R+
Sbjct: 207 AITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPG------SSCIGADPN--RN 258
Query: 216 LNRSFPDQFSTGEP-------PALDEVPEVRALIEWIRRN-KFVLSGNLHGGSVVASYPF 267
N SF + ++ P P + EV++++++I+++ F +LH S + YP+
Sbjct: 259 WNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPY 318
Query: 268 DDSPEHKATGIYSKTSDDEVFKYLAKAYAS 297
S + D+V + AKA AS
Sbjct: 319 GYSVKKAP----DAEELDKVARLAAKALAS 344
Score = 63.2 bits (152), Expect = 2e-09
Identities = 55/255 (21%), Positives = 102/255 (40%), Gaps = 30/255 (11%)
Query: 898 TTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLT 957
T ++ + L+ + E RSS+N Y HS + + + + ++P +
Sbjct: 90 TIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAY--HSLEAIYHEMDNIAADFPDLARRV 147
Query: 958 NLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKK 1017
+G S E R ++ L+ S V P + AGIH + + A + +Y++
Sbjct: 148 KIGHSFENRPMYVLKFSTGKGV---RRPAVWLNAGIHSREWISQATAIWTARKIVSDYQR 204
Query: 1018 NPAVTQLVDRTRIVIVPSLNPDG--------------RERAQEKDCTSKIGQTNARGKDL 1063
+PA+T ++++ I ++P NPDG R R C N
Sbjct: 205 DPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNASFA 264
Query: 1064 DTDFTNNA-----------SQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQT 1112
++N S+ E K++++ + + +F + L S L+ YPY V+
Sbjct: 265 GKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKK 324
Query: 1113 VENKETLKHLASLYA 1127
+ E L +A L A
Sbjct: 325 APDAEELDKVARLAA 339
Score = 57.0 bits (136), Expect = 1e-07
Identities = 62/272 (22%), Positives = 106/272 (38%), Gaps = 50/272 (18%)
Query: 517 ANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLN 576
A ++P++ R +G S E+R +YV++ S GV P +H E + + +
Sbjct: 137 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPA---VWLNAGIHSREWISQATAIW 193
Query: 577 LIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSI--SVIGRNNSNN---F 631
+ ++ DP +T ++ I L+P NPDGY +Q + + RN ++
Sbjct: 194 TARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGA 253
Query: 632 DLNRNFPDQFVQITDPTQP--------------ETIAVMSWMKSY-PFVLSANLHGGSLV 676
D NRN+ F P E +V+ +++ + F +LH S +
Sbjct: 254 DPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQL 313
Query: 677 VNYPFDDDEQGLATYSKSPD----DAVFQQIALSYSKENSQMFQ-GRPCKNMYPNEYFPH 731
+ YP+ + K+PD D V + A + + + +Q G C +YP
Sbjct: 314 LMYPYG------YSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYP------ 361
Query: 732 GITNGASWYNVPGGMQDWNYLQTNCFEVTIEL 763
G DW Y F T EL
Sbjct: 362 ----------ASGSSIDWAYDNGIKFAFTFEL 383
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 63.9 bits (154), Expect = 1e-09
Identities = 53/227 (23%), Positives = 100/227 (44%), Gaps = 30/227 (13%)
Query: 933 YHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAG 992
YH+ +++S+ + LV +P + + N+G S E R + L+ S + ++P I AG
Sbjct: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS-----TGGDKPAIWLDAG 177
Query: 993 IHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKD---- 1048
IH V L A + +Y K+P++T ++D I ++P NPDG +Q K+
Sbjct: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237
Query: 1049 -CTSKIGQTNARGKDLDTDF--------------------TNNASQPETKAIIENLIQKQ 1087
SK+ + G D + ++ + S+ E K+I++ +
Sbjct: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHG 297
Query: 1088 DFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMH 1134
+ L S L+ +PY +++ + L +A A + S+H
Sbjct: 298 KVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLH 344
Score = 61.6 bits (148), Expect = 5e-09
Identities = 74/319 (23%), Positives = 118/319 (36%), Gaps = 86/319 (26%)
Query: 59 YHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAG 118
YH E S + A PGL +IG S E RP+ VL+ + G GD
Sbjct: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTG-------GD------- 168
Query: 119 PDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYL 178
+P + L +H E V++ ++ A ++ + Y + DP + +L+ D++L
Sbjct: 169 ----------KPAIWLDAGIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFL 217
Query: 179 LPSLNPDGF-------------------------ERAREGDCGFGDGGPSGASGRDNSRG 213
LP NPDG+ + R D GFG G S D+ G
Sbjct: 218 LPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHG 277
Query: 214 RDLNRSFPDQFSTGEPPALDEVPEVRALIEWIR-RNKFVLSGNLHGGSVVASYPFDDSPE 272
P A EV EV++++++I+ K LH S + +P+
Sbjct: 278 ---------------PSANSEV-EVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYG---- 317
Query: 273 HKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEG 332
+K T + EV + A++ S H P C + Y G
Sbjct: 318 YKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPIC---------------SVIYQASG 362
Query: 333 GMQDYNYVWANCFEITLEL 351
G D++Y + + EL
Sbjct: 363 GSIDWSYDYGIKYSFAFEL 381
Score = 48.5 bits (114), Expect = 4e-05
Identities = 54/269 (20%), Positives = 106/269 (39%), Gaps = 42/269 (15%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H ++ + E+P + ++G S E+R + V++ S +P
Sbjct: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAIWLDAG 177
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSI-- 620
+H E V + L + ++G DP +T ++ I L+P NPDGY SQ + +
Sbjct: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237
Query: 621 ---SVIGRNNSNNFDLNRNF--------------PDQFVQITDPTQPETIAVMSWMKSYP 663
S + + D NRN+ D + + ++ E +++ ++KS+
Sbjct: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHG 297
Query: 664 FVLS-ANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPCKN 722
V + LH S ++ +P+ L + + + V Q+ A S + ++ P +
Sbjct: 298 KVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSE--VAQKAAQSLRSLHGTKYKVGPICS 355
Query: 723 MYPNEYFPHGITNGASWYNVPGGMQDWNY 751
+ Y GG DW+Y
Sbjct: 356 VI---------------YQASGGSIDWSY 369
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 58.5 bits (140), Expect = 4e-08
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 41/283 (14%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H ++ ++ +P++ +G S E LYV+++S G + +
Sbjct: 123 YHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDCG 179
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSI-- 620
+H E + L I ++ + +G + T+L+ ++MP +N DGY+ S + + +
Sbjct: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239
Query: 621 ---SVIGRNNSNNFDLNRNF---------------PDQFVQITDPTQPETIAVMSWMKSY 662
S N+ DLNRNF + + + ++PE AV S+++
Sbjct: 240 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 299
Query: 663 PFVLSA--NLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPC 720
+ A ++H S + +P+ T SKS D ++++L S+ R
Sbjct: 300 INQIKAYISMHSYSQHIVFPYS------YTRSKSKD---HEELSLVASE------AVRAI 344
Query: 721 KNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIEL 763
+ N + HG + Y PGG DW Y + TIEL
Sbjct: 345 EKTSKNTRYTHG-HGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386
Score = 33.9 bits (76), Expect = 1.1
Identities = 64/318 (20%), Positives = 117/318 (36%), Gaps = 62/318 (19%)
Query: 50 AAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPE 109
A+ +++Y+ E+ S + E P + IG S E PL+VL+++
Sbjct: 115 ASASYYEQYHSLNEIYSWI-EFITERHPDMLTKIHIGSSFEKYPLYVLKVS--------- 164
Query: 110 GDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVR 169
G + A +A + + +H E +S ++ + Y +
Sbjct: 165 ---GKEQAAKNA----------IWIDCGIHAREWISPAFCLWFIGHITQFYGIIG-QYTN 210
Query: 170 LLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEP 229
LL D Y++P +N DG++ + + + + A+ ++ G DLNR+F + E
Sbjct: 211 LLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYAN--NHCIGTDLNRNFASKHWCEEG 268
Query: 230 PAL------------DEVPEVRALIEWIRRN----KFVLSGNLHGGSVVASYPFDDSPEH 273
+ + PEV+A+ ++RRN K +S + + +V Y +
Sbjct: 269 ASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY------ 322
Query: 274 KATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGG 333
SK+ D E +A + G ET Y GG
Sbjct: 323 ----TRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETL----------YLAPGG 368
Query: 334 MQDYNYVWANCFEITLEL 351
D+ Y + T+EL
Sbjct: 369 GDDWIYDLGIKYSFTIEL 386
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 53.5 bits (127), Expect = 1e-06
Identities = 54/252 (21%), Positives = 102/252 (40%), Gaps = 34/252 (13%)
Query: 902 FETLIKDLSA-----ENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNL 956
+ET+I+D+ + + + + R+ S YH+ +++ +FL LV PH+ +
Sbjct: 86 YETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSK 145
Query: 957 TNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYK 1016
+G + E R I+ L+ S + P I GIH V + A+ + +Y
Sbjct: 146 IQIGNTYEGRPIYVLKFS----TGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYG 201
Query: 1017 KNPAVTQLVDRTRIVIVPSLNPDG-----------RERAQEKDCTSKIGQTNARGKDLDT 1065
++ A T ++D I + NPDG R+ + IG R D
Sbjct: 202 QDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGF 261
Query: 1066 DFTNNASQP--------------ETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQ 1111
+ +S P E K+I++ + + +++ S L+ YPY +
Sbjct: 262 GLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTE 321
Query: 1112 TVENKETLKHLA 1123
V +++ L L+
Sbjct: 322 PVPDQDELDQLS 333
Score = 44.7 bits (104), Expect = 6e-04
Identities = 55/265 (20%), Positives = 99/265 (37%), Gaps = 70/265 (26%)
Query: 59 YHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAG 118
YH E + A P L IG + EGRP++VL+ + G GS
Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG-GS------------- 167
Query: 119 PDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYL 178
RP + + +H E V++ ++ A+++ Y + D +L+T D++L
Sbjct: 168 ---------KRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQ-DAAFTAILDTLDIFL 217
Query: 179 LPSLNPDGF-------------------------ERAREGDCGFGDGGPSGASGRDNSRG 213
NPDGF + R D GFG G S + G
Sbjct: 218 EIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHG 277
Query: 214 RDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSG-NLHGGSVVASYPFDDSPE 272
+ N EV++++++++ + + + ++H S + YP+
Sbjct: 278 KFANSEV----------------EVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYG---- 317
Query: 273 HKATGIYSKTSDDEVFKYLAKAYAS 297
+K + + D++ K A AS
Sbjct: 318 YKTEPVPDQDELDQLSKAAVTALAS 342
Score = 34.3 bits (77), Expect = 0.85
Identities = 24/109 (22%), Positives = 45/109 (41%), Gaps = 4/109 (3%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H ++ FL E P++ +G + E R +YV++ S P
Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKR----PAIWIDTG 177
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGY 611
+H E V + + + + +++G D T ++ I L NPDG+
Sbjct: 178 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGF 226
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 52.0 bits (123), Expect = 4e-06
Identities = 69/362 (19%), Positives = 139/362 (38%), Gaps = 63/362 (17%)
Query: 444 NVVVKEGPATEVDFSLRPTVTSVIPDTTE--AVSTASTVAIPNILSGTSSSYQPI----- 496
N++ + T++DF +VT + P +T V TV + N+L Y+ +
Sbjct: 39 NIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLR 98
Query: 497 ---------QPKDFHHHH-----FPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVME 542
+ + H + + +E + ++ A E P + +G + E R +Y+++
Sbjct: 99 NVVEAQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLK 158
Query: 543 ISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHL 602
+ G +P H E + + + +G + +VT+L+ ++
Sbjct: 159 V----GKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYV 214
Query: 603 MPSMNPDGY-----------EKSQEGDSISVIGRNNSNNFD-------LNRNFPDQ-FVQ 643
+P +N DGY + S IG + + NFD +RN D+ +
Sbjct: 215 LPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCG 274
Query: 644 ITDPTQPETIAVMSWMKSYPFVLSA--NLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQ 701
++ ET A+ ++++ + A +H S ++ YP+ Y ++A
Sbjct: 275 PAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS------YAYKLGENNAELN 328
Query: 702 QIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTI 761
+A + KE + + + + +G + Y GG DW Y Q + T
Sbjct: 329 ALAKATVKELASLHGTK----------YTYG-PGATTIYPAAGGSDDWAYDQGIRYSFTF 377
Query: 762 EL 763
EL
Sbjct: 378 EL 379
Score = 44.7 bits (104), Expect = 6e-04
Identities = 64/289 (22%), Positives = 109/289 (37%), Gaps = 55/289 (19%)
Query: 55 FDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGP 114
+++Y E +E+ ++ A P L IG + EGR +++L++ G AG
Sbjct: 116 YEKYNKWETIEAWTQQVATEN-PALISRSVIGTTFEGRAIYLLKV----------GKAGQ 164
Query: 115 DAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTT 174
+ +P + + H E +S + RE Y R + ++ LL+
Sbjct: 165 N-------------KPAIFMDCGFHAREWISPAFCQWFVREAVRTYGR-EIQVTELLDKL 210
Query: 175 DVYLLPSLNPDGF----------ERAREGDCGFGDGGPSGASGRDNSRGRD-------LN 217
D Y+LP LN DG+ + R G S G D +R D +
Sbjct: 211 DFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTG------SSCIGTDPNRNFDAGWCEIGAS 264
Query: 218 RSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSG--NLHGGSVVASYPFDDSPEHKA 275
R+ D+ G PA + E +AL ++IR + +H S + YP+ + +
Sbjct: 265 RNPCDETYCG--PAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGE 322
Query: 276 TGIYSKTSDDEVFKYLAKAYASNH---PIMKTGEPHCPGDEDETFKDGI 321
K LA + + + P T P G +D + GI
Sbjct: 323 NNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGI 371
Score = 40.0 bits (92), Expect = 0.015
Identities = 48/233 (20%), Positives = 88/233 (37%), Gaps = 38/233 (16%)
Query: 932 RYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVA 991
+Y+ ++ + + + + P + + + +G + E R I+ L++ + +P I
Sbjct: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGK----AGQNKPAIFMDC 173
Query: 992 GIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDG----------- 1040
G H + Y + VT+L+D+ ++P LN DG
Sbjct: 174 GFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFW 233
Query: 1041 RERAQEKDCTSKIGQTNARGKD------------LDTDFTNNA--SQPETKAIIENLIQK 1086
R+ +S IG R D D + A S+ ETKA+ + + K
Sbjct: 234 RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 293
Query: 1087 -QDFSLSVALDGGSMLVTYPYDKPVQTVEN--------KETLKHLASLYANNH 1130
+ + S ++ YPY + EN K T+K LASL+ +
Sbjct: 294 LSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKY 346
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 49.3 bits (116), Expect = 3e-05
Identities = 51/263 (19%), Positives = 108/263 (41%), Gaps = 33/263 (12%)
Query: 901 EFETLIKDL--SAENGLESLMLRSSSNLALALYR-YHSYKDLSEFLRGLVMNYPHITNLT 957
+++ LI+DL + E G R+ +L+ Y YHS +++ ++ L + + ++
Sbjct: 104 QYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMF 163
Query: 958 NLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKK 1017
++G+S E R ++ L++ + + + GIH +G + L YK
Sbjct: 164 SIGRSYEGRSLFILKLGRRSRLKRA----VWIDCGIHAREWIGPAFCQWFVKEALLTYKS 219
Query: 1018 NPAVTQLVDRTRIVIVPSLNPDGRERAQEKD-----CTSKIGQTNARGKDLDTDFTNN-- 1070
+PA+ ++++ I+P N DG + D S+ + RG D + ++
Sbjct: 220 DPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWC 279
Query: 1071 ------------------ASQPETKAIIENLIQ-KQDFSLSVALDGGSMLVTYPYDKPVQ 1111
S+PE KA+ L + ++ ++ + ++ YPY
Sbjct: 280 DEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYA 339
Query: 1112 TVENKETLKHLASLYANNHPSMH 1134
T+ N ++ A N S++
Sbjct: 340 TIPNFRCVESAAYKAVNALQSVY 362
Score = 47.4 bits (111), Expect = 1e-04
Identities = 52/226 (23%), Positives = 96/226 (42%), Gaps = 40/226 (17%)
Query: 55 FDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGP 114
++ Y+ EE+++ + GL +FSIGRS EGR L++L+L G S +
Sbjct: 136 YEVYHSLEEIQNWMHHLNKTH-SGLIHMFSIGRSYEGRSLFILKL--GRRSRLKRA---- 188
Query: 115 DAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTT 174
V + +H E + + +E Y+ DP + ++LN
Sbjct: 189 -----------------VWIDCGIHAREWIGPAFCQWFVKEALLTYK-SDPAMRKMLNHL 230
Query: 175 DVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFP----DQFSTGEP- 229
Y++P N DG+ + D + + R RG D NR++ D+ ++ P
Sbjct: 231 YFYIMPVFNVDGYHFSWTNDRFWRK--TRSRNSRFRCRGVDANRNWKVKWCDEGASMHPC 288
Query: 230 ------PALDEVPEVRALIEWIRRNKFVLSGNL--HGGSVVASYPF 267
P + PEV+A+ ++R+++ + L H + + YP+
Sbjct: 289 DDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPY 334
Score = 45.8 bits (107), Expect = 3e-04
Identities = 36/200 (18%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H +++ ++ + + ++S+G+S E R L+++++ + +
Sbjct: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDC----G 194
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
+H E +G ++ + +DP + ++++ ++MP N DGY S D
Sbjct: 195 IHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWR 254
Query: 623 IGRNNSNNF-----DLNRNF--------------PDQFVQITDPTQPETIAVMSWMKSYP 663
R+ ++ F D NRN+ D + ++PE AV ++++ +
Sbjct: 255 KTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHR 314
Query: 664 FVLSANL--HGGSLVVNYPF 681
+ A L H + ++ YP+
Sbjct: 315 KHIRAYLSFHAYAQMLLYPY 334
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 48.9 bits (115), Expect = 3e-05
Identities = 54/250 (21%), Positives = 103/250 (41%), Gaps = 33/250 (13%)
Query: 900 KEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNL 959
K+ + L+ D + +S L S+N + + YH+ +++ ++ VM + I + +
Sbjct: 108 KDIQVLL-DEERQAMAKSRRLERSTN-SFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQI 165
Query: 960 GQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNP 1019
G S E + I L+ S + P I GIH + + A + +Y K+
Sbjct: 166 GNSFENQSILVLKFSTGGS----RHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDR 221
Query: 1020 AVTQLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARGKDLDTDFTNN--- 1070
+T +++ I I NPDG R K+ + + G G DL+ ++ +
Sbjct: 222 VLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPG-IFCIGVDLNRNWKSGFGG 280
Query: 1071 -----------------ASQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTV 1113
S+PE AI+ + +F +++ S ++ YPY + ++ V
Sbjct: 281 NGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPV 340
Query: 1114 ENKETLKHLA 1123
N+ L LA
Sbjct: 341 SNQRELYDLA 350
Score = 42.0 bits (97), Expect = 0.004
Identities = 44/234 (18%), Positives = 100/234 (42%), Gaps = 36/234 (15%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H ++ ++ F E+ +I +G S E++ + V++ S H P
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDTG 194
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
+H E + + + ++G D +TD+++ I + NPDG+ + S++
Sbjct: 195 IHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTH---SMNR 251
Query: 623 IGRNNSN--------NFDLNRNFPDQF---VQITDP-----------TQPETIAVMSWMK 660
+ R N + DLNRN+ F ++P ++PE A+++++
Sbjct: 252 LWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFIT 311
Query: 661 SY-PFVLSANLHGGSLVVNYPFD------DDEQGLATYSKSPDDAVFQQIALSY 707
++ F ++H S ++ YP+ +++ L +K +A+++ + Y
Sbjct: 312 AHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEY 365
Score = 34.3 bits (77), Expect = 0.85
Identities = 36/158 (22%), Positives = 60/158 (37%), Gaps = 31/158 (19%)
Query: 130 PQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFER 189
P + + +H E ++ I+ A ++ + Y + D L +LN D+++ NPDGF
Sbjct: 187 PAIWIDTGIHSREWITHATGIWTANKIVSDYGK-DRVLTDILNAMDIFIELVTNPDGFAF 245
Query: 190 AREGDCGFGDGGPSGASGRDNSR--------GRDLNRSFPDQF-----------STGEPP 230
R N G DLNR++ F T P
Sbjct: 246 THS----------MNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGP 295
Query: 231 ALDEVPEVRALIEWI-RRNKFVLSGNLHGGSVVASYPF 267
+ PEV A++ +I F ++H S + YP+
Sbjct: 296 SPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 48.9 bits (115), Expect = 3e-05
Identities = 54/250 (21%), Positives = 103/250 (41%), Gaps = 33/250 (13%)
Query: 900 KEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNL 959
K+ + L+ D + +S L S+N + + YH+ +++ ++ VM + I + +
Sbjct: 108 KDIQVLL-DEERQAMAKSRRLERSTN-SFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQI 165
Query: 960 GQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNP 1019
G S E + I L+ S + P I GIH + + A + +Y K+
Sbjct: 166 GNSFENQSILVLKFSTGGS----RHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDR 221
Query: 1020 AVTQLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARGKDLDTDFTNN--- 1070
+T +++ I I NPDG R K+ + + G G DL+ ++ +
Sbjct: 222 VLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPG-IFCIGVDLNRNWKSGFGG 280
Query: 1071 -----------------ASQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTV 1113
S+PE AI+ + +F +++ S ++ YPY + ++ V
Sbjct: 281 NGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPV 340
Query: 1114 ENKETLKHLA 1123
N+ L LA
Sbjct: 341 SNQRELYDLA 350
Score = 42.0 bits (97), Expect = 0.004
Identities = 44/234 (18%), Positives = 100/234 (42%), Gaps = 36/234 (15%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H ++ ++ F E+ +I +G S E++ + V++ S H P
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDTG 194
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
+H E + + + ++G D +TD+++ I + NPDG+ + S++
Sbjct: 195 IHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTH---SMNR 251
Query: 623 IGRNNSN--------NFDLNRNFPDQF---VQITDP-----------TQPETIAVMSWMK 660
+ R N + DLNRN+ F ++P ++PE A+++++
Sbjct: 252 LWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFIT 311
Query: 661 SY-PFVLSANLHGGSLVVNYPFD------DDEQGLATYSKSPDDAVFQQIALSY 707
++ F ++H S ++ YP+ +++ L +K +A+++ + Y
Sbjct: 312 AHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEY 365
Score = 34.3 bits (77), Expect = 0.85
Identities = 36/158 (22%), Positives = 60/158 (37%), Gaps = 31/158 (19%)
Query: 130 PQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFER 189
P + + +H E ++ I+ A ++ + Y + D L +LN D+++ NPDGF
Sbjct: 187 PAIWIDTGIHSREWITHATGIWTANKIVSDYGK-DRVLTDILNAMDIFIELVTNPDGFAF 245
Query: 190 AREGDCGFGDGGPSGASGRDNSR--------GRDLNRSFPDQF-----------STGEPP 230
R N G DLNR++ F T P
Sbjct: 246 THS----------MNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGP 295
Query: 231 ALDEVPEVRALIEWI-RRNKFVLSGNLHGGSVVASYPF 267
+ PEV A++ +I F ++H S + YP+
Sbjct: 296 SPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 48.5 bits (114), Expect = 4e-05
Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 22/178 (12%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H ++ ++R + +Y + + LG + E+ +Y ++IS G P + + G
Sbjct: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSG--NPKKIIWMDCG- 106
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
+H E + ++ + +N + + L+ N +++P +N DGY + D +
Sbjct: 107 IHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWR 166
Query: 623 IGRNNSNN-----FDLNRNF-------------PDQFVQITDP-TQPETIAVMSWMKS 661
R+ NN DLNRNF DQ T P ++PET AV S+++S
Sbjct: 167 KSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224
Score = 40.8 bits (94), Expect = 0.009
Identities = 58/258 (22%), Positives = 97/258 (37%), Gaps = 52/258 (20%)
Query: 908 DLSAENGLESLMLRSSSNLALALYRYHSYK---DLSEFLRGLVMNYPHITNLTNLGQSTE 964
D S + ++ +S S +L Y Y+ Y ++ E++R + Y + LG + E
Sbjct: 22 DRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYE 81
Query: 965 YRHIWSLEISNKPNVSEPEEPK--IRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPAVT 1022
++ L+IS PK I GIH + + + N+K N ++
Sbjct: 82 THPMYYLKISQPSG-----NPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIR 136
Query: 1023 QLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARGKDLDTDF--------- 1067
+L+ ++P LN DG +R K S G DL+ +F
Sbjct: 137 KLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKS-RSPHNNGTCFGTDLNRNFNASWCSIGA 195
Query: 1068 -----------TNNASQPETKAIIENLIQKQDFSLS-VALDGGSMLVTYPYDKPVQTVEN 1115
T S+PETKA+ + K+D L + + L+ PY +N
Sbjct: 196 SRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYG----YTKN 251
Query: 1116 KETLKHLASLYANNHPSM 1133
K ++NHP M
Sbjct: 252 K----------SSNHPEM 259
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 47.0 bits (110), Expect = 1e-04
Identities = 59/267 (22%), Positives = 104/267 (38%), Gaps = 37/267 (13%)
Query: 888 SSSTNDASDPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLV 947
S + A D +E LI DL E + ++ + +Y++++ + + ++
Sbjct: 75 SQAIQSALDQNKMHYEILIHDLQEEIE-KQFDVKEDIPGRHSYAKYNNWEKIVAWTEKMM 133
Query: 948 MNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV-AGIHGNAPVGTELLLA 1006
YP + + +G + E ++ L+I K E K F GIH V
Sbjct: 134 DKYPEMVSRIKIGSTVEDNPLYVLKIGEKN-----ERRKAIFTDCGIHAREWVSPAFCQW 188
Query: 1007 LAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARG 1060
Y +N +T+L+DR I+P N DG + R K+ SK + G
Sbjct: 189 FVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKN-RSKNQNSKCIG 247
Query: 1061 KDLDTDF---------TNN-----------ASQPETKAIIENLIQK--QDFSLSVALDGG 1098
DL+ +F TN+ S+ ETKA + N I+ + + +
Sbjct: 248 TDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKA-VTNFIRSHLNEIKVYITFHSY 306
Query: 1099 SMLVTYPYDKPVQTVENKETLKHLASL 1125
S ++ +PY + N E L +A +
Sbjct: 307 SQMLLFPYGYTSKLPPNHEDLAKVAKI 333
Score = 46.6 bits (109), Expect = 2e-04
Identities = 43/200 (21%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
++++ + + + ++YP + +G +VE LYV++I + +E + F G
Sbjct: 119 YNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEK---NERRKAIFTDCG- 174
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
+H E V + K +G + +T L+ +++P N DGY S + +
Sbjct: 175 IHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWR 234
Query: 623 IGRNNSNN-----FDLNRNFPDQFVQITDPTQP--------------ETIAVMSWMKSY- 662
R+ + N DLNRNF + I + P ET AV ++++S+
Sbjct: 235 KNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHL 294
Query: 663 -PFVLSANLHGGSLVVNYPF 681
+ H S ++ +P+
Sbjct: 295 NEIKVYITFHSYSQMLLFPY 314
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 47.0 bits (110), Expect = 1e-04
Identities = 52/246 (21%), Positives = 101/246 (41%), Gaps = 33/246 (13%)
Query: 900 KEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNL 959
K+ + L+ D + +S L S+N + + YH+ +++ ++ VM + I + +
Sbjct: 108 KDIQVLL-DEERQAMAKSRRLERSTN-SFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQI 165
Query: 960 GQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNP 1019
G S E + I L+ S + P I GIH + + A + +Y K+
Sbjct: 166 GNSFENQSILVLKFSTGGS----RHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDR 221
Query: 1020 AVTQLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARGKDLDTDFTNN--- 1070
+T +++ I I NPDG R K+ + + G G DL+ ++ +
Sbjct: 222 VLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPG-IFCIGVDLNRNWKSGFGG 280
Query: 1071 -----------------ASQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTV 1113
S+PE AI+ + +F +++ S ++ YPY + ++ V
Sbjct: 281 NGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPV 340
Query: 1114 ENKETL 1119
N+ L
Sbjct: 341 SNQREL 346
Score = 41.6 bits (96), Expect = 0.005
Identities = 40/202 (19%), Positives = 87/202 (43%), Gaps = 30/202 (14%)
Query: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
+H ++ ++ F E+ +I +G S E++ + V++ S H P
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDTG 194
Query: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
+H E + + + ++G D +TD+++ I + NPDG+ + S++
Sbjct: 195 IHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTH---SMNR 251
Query: 623 IGRNNSN--------NFDLNRNFPDQF---VQITDP-----------TQPETIAVMSWMK 660
+ R N + DLNRN+ F ++P ++PE A+++++
Sbjct: 252 LWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFIT 311
Query: 661 SY-PFVLSANLHGGSLVVNYPF 681
++ F ++H S ++ YP+
Sbjct: 312 AHGNFKALISIHSYSQMLMYPY 333
Score = 34.3 bits (77), Expect = 0.85
Identities = 36/158 (22%), Positives = 60/158 (37%), Gaps = 31/158 (19%)
Query: 130 PQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFER 189
P + + +H E ++ I+ A ++ + Y + D L +LN D+++ NPDGF
Sbjct: 187 PAIWIDTGIHSREWITHATGIWTANKIVSDYGK-DRVLTDILNAMDIFIELVTNPDGFAF 245
Query: 190 AREGDCGFGDGGPSGASGRDNSR--------GRDLNRSFPDQF-----------STGEPP 230
R N G DLNR++ F T P
Sbjct: 246 THS----------MNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGP 295
Query: 231 ALDEVPEVRALIEWI-RRNKFVLSGNLHGGSVVASYPF 267
+ PEV A++ +I F ++H S + YP+
Sbjct: 296 SPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 40.4 bits (93), Expect = 0.012
Identities = 25/131 (19%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 520 YPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIE 579
+ + ++S+G+S E R L+++++ + + +H E +G ++
Sbjct: 8 HSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDC----GIHAREWIGPAFCQWFVK 63
Query: 580 YLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISVIGRNNSNNF-----DLN 634
+ +DP + ++++ ++MP N DGY S D R+ ++ F D N
Sbjct: 64 EALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDAN 123
Query: 635 RNFPDQFVQIT 645
RN+ ++ ++
Sbjct: 124 RNWKVKWCDVS 134
Score = 40.0 bits (92), Expect = 0.015
Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 26/143 (18%)
Query: 78 GLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGN 137
GL +FSIGRS EGR L++L+L G S + + V +
Sbjct: 10 GLIHMFSIGRSYEGRSLFILKL--GRRSRL---------------------KRAVWIDCG 46
Query: 138 MHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGF 197
+H E + + +E Y + DP + ++LN Y++P N DG+ + D +
Sbjct: 47 IHAREWIGPAFCQWFVKEALLTY-KSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFW 105
Query: 198 GDGGPSGASGRDNSRGRDLNRSF 220
+ R RG D NR++
Sbjct: 106 RK--TRSRNSRFRCRGVDANRNW 126
Score = 33.9 bits (76), Expect = 1.1
Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Query: 953 ITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLC 1012
+ ++ ++G+S E R ++ L++ + + + GIH +G +
Sbjct: 11 LIHMFSIGRSYEGRSLFILKLGRRSRLKRA----VWIDCGIHAREWIGPAFCQWFVKEAL 66
Query: 1013 LNYKKNPAVTQLVDRTRIVIVPSLNPDG 1040
L YK +PA+ ++++ I+P N DG
Sbjct: 67 LTYKSDPAMRKMLNHLYFYIMPVFNVDG 94
>gi|190194403 ATP/GTP binding protein-like 4 [Homo sapiens]
Length = 503
Score = 34.7 bits (78), Expect = 0.65
Identities = 43/190 (22%), Positives = 72/190 (37%), Gaps = 44/190 (23%)
Query: 483 PNILSGTSSSYQPIQPKDFHHHHFP--------------DMEIFLRRFANEYP-NITRLY 527
P + S + +Q + PK+ +++ P D E + +FA YP TR
Sbjct: 116 PMVKSTSRPKWQRLPPKNVYYYRCPDHRKNYVMSFAFCFDREEDIYQFAYCYPYTYTRFQ 175
Query: 528 -----------------SLGKSVESRELYVMEISDNPGVHEPGEPEFKYI-GNMHGNEVV 569
LG+SV+ R+L ++ I+ + E E + +I G +H E
Sbjct: 176 HYLDSLQKRNMDYFFREQLGQSVQQRKLDLLTITSPDNLREGAEQKVVFITGRVHPGETP 235
Query: 570 GRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISVIGRNNSN 629
+ +I++L P L + P +NPDG S+
Sbjct: 236 SSFVCQGIIDFLVSQ---HPIACVLREYLVFKIAPMLNPDGVYLGNYRCSLM-------- 284
Query: 630 NFDLNRNFPD 639
FDLNR++ D
Sbjct: 285 GFDLNRHWLD 294
>gi|4759258 zinc finger, BED-type containing 1 [Homo sapiens]
Length = 694
Score = 33.9 bits (76), Expect = 1.1
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 1166 KDYSVTYGHCPEITVYTSCCYF--PSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKT 1223
K+ S TY PEI ++ + F P RLP L A ++ + + +VE KG+ VKD
Sbjct: 453 KELSKTYQETPEIDMFLNVATFLDPRYKRLPFLSAFERQQVENRVVEEAKGLLDKVKDGG 512
Query: 1224 GKPISKAVIVLNE 1236
+P + + E
Sbjct: 513 YRPAEDKIFPVPE 525
>gi|4506321 protein tyrosine phosphatase, receptor type, N precursor
[Homo sapiens]
Length = 979
Score = 33.5 bits (75), Expect = 1.4
Identities = 40/145 (27%), Positives = 59/145 (40%), Gaps = 26/145 (17%)
Query: 104 GSLIPEGDAGPDAAGP--DAAGPLLPGRPQVKLV-----GNMHGD-------ETVSRQVL 149
GS + EG G + GP A P L R K + G+ +GD + L
Sbjct: 219 GSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGL 278
Query: 150 IYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRD 209
+YLA+EL A R PRL +++ +P+G+E+ GD G P+
Sbjct: 279 LYLAQELPAPSRARVPRLPEQGSSSRA----EDSPEGYEKEGLGDRGEKPASPAVQPDAA 334
Query: 210 NSR--------GRDLNRSFPDQFST 226
R G +L + P+Q ST
Sbjct: 335 LQRLAAVLAGYGVELRQLTPEQLST 359
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 32.7 bits (73), Expect = 2.5
Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 15/125 (12%)
Query: 1059 RGKDLDTDFTNNASQPETKAIIENLIQKQD--------FSLSVALDGGSMLVTYPYDKPV 1110
+G+ L+ D +Q E +EN++ D F++S +D L YP K V
Sbjct: 375 QGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDN---LYGYPEGKDV 431
Query: 1111 QTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSV 1170
+ET+K + + +A+ H + +D + A+ HS+ GS +
Sbjct: 432 L----RETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYA 487
Query: 1171 TYGHC 1175
Y HC
Sbjct: 488 FYHHC 492
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 32.3 bits (72), Expect = 3.2
Identities = 17/56 (30%), Positives = 25/56 (44%)
Query: 858 VKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTKEFETLIKDLSAEN 913
++ EG N L S+ N + KGKG ++ S + E + IKD EN
Sbjct: 56 IEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELEN 111
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 32.3 bits (72), Expect = 3.2
Identities = 17/56 (30%), Positives = 25/56 (44%)
Query: 858 VKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTKEFETLIKDLSAEN 913
++ EG N L S+ N + KGKG ++ S + E + IKD EN
Sbjct: 56 IEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELEN 111
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,114,293
Number of Sequences: 37866
Number of extensions: 2610842
Number of successful extensions: 8046
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 7748
Number of HSP's gapped (non-prelim): 134
length of query: 1380
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1265
effective length of database: 13,892,928
effective search space: 17574553920
effective search space used: 17574553920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.