Search of human proteins with 221316669

Search of human proteins with 221316669

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221316669 oxoglutarate dehydrogenase-like isoform c [Homo
sapiens]
         (801 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221316669 oxoglutarate dehydrogenase-like isoform c [Homo sap...  1642   0.0  
gi|221316665 oxoglutarate dehydrogenase-like isoform b [Homo sap...  1642   0.0  
gi|221316661 oxoglutarate dehydrogenase-like isoform a [Homo sap...  1642   0.0  
gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...  1396   0.0  
gi|38788380 dehydrogenase E1 and transketolase domain containing...   564   e-160
gi|51873038 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...   328   9e-90
gi|224586880 Ras protein-specific guanine nucleotide-releasing f...    34   0.61 
gi|24797099 Ras protein-specific guanine nucleotide-releasing fa...    34   0.61 
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    31   4.0  
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    31   4.0  
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    31   4.0  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...    31   5.2  
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]             30   8.9  

>gi|221316669 oxoglutarate dehydrogenase-like isoform c [Homo
           sapiens]
          Length = 801

 Score = 1642 bits (4251), Expect = 0.0
 Identities = 801/801 (100%), Positives = 801/801 (100%)

Query: 1   MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60
           MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG
Sbjct: 1   MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60

Query: 61  CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120
           CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE
Sbjct: 61  CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120

Query: 121 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180
           GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK
Sbjct: 121 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180

Query: 181 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 240
           VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT
Sbjct: 181 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 240

Query: 241 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 300
           DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT
Sbjct: 241 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 300

Query: 301 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 360
           QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK
Sbjct: 301 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 360

Query: 361 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 420
           HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR
Sbjct: 361 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 420

Query: 421 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 480
           ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP
Sbjct: 421 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 480

Query: 481 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 540
           MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI
Sbjct: 481 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 540

Query: 541 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 600
           STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY
Sbjct: 541 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 600

Query: 601 DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 660
           DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR
Sbjct: 601 DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 660

Query: 661 VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 720
           VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ
Sbjct: 661 VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 720

Query: 721 EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 780
           EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL
Sbjct: 721 EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 780

Query: 781 VSLKKFLDTAFNLQAFEGKTF 801
           VSLKKFLDTAFNLQAFEGKTF
Sbjct: 781 VSLKKFLDTAFNLQAFEGKTF 801


>gi|221316665 oxoglutarate dehydrogenase-like isoform b [Homo
           sapiens]
          Length = 953

 Score = 1642 bits (4251), Expect = 0.0
 Identities = 801/801 (100%), Positives = 801/801 (100%)

Query: 1   MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60
           MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG
Sbjct: 153 MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 212

Query: 61  CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120
           CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE
Sbjct: 213 CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 272

Query: 121 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180
           GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK
Sbjct: 273 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 332

Query: 181 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 240
           VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT
Sbjct: 333 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 392

Query: 241 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 300
           DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT
Sbjct: 393 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 452

Query: 301 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 360
           QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK
Sbjct: 453 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 512

Query: 361 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 420
           HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR
Sbjct: 513 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 572

Query: 421 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 480
           ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP
Sbjct: 573 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 632

Query: 481 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 540
           MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI
Sbjct: 633 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 692

Query: 541 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 600
           STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY
Sbjct: 693 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 752

Query: 601 DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 660
           DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR
Sbjct: 753 DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 812

Query: 661 VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 720
           VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ
Sbjct: 813 VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 872

Query: 721 EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 780
           EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL
Sbjct: 873 EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 932

Query: 781 VSLKKFLDTAFNLQAFEGKTF 801
           VSLKKFLDTAFNLQAFEGKTF
Sbjct: 933 VSLKKFLDTAFNLQAFEGKTF 953


>gi|221316661 oxoglutarate dehydrogenase-like isoform a [Homo sapiens]
          Length = 1010

 Score = 1642 bits (4251), Expect = 0.0
 Identities = 801/801 (100%), Positives = 801/801 (100%)

Query: 1    MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60
            MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG
Sbjct: 210  MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 269

Query: 61   CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120
            CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE
Sbjct: 270  CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 329

Query: 121  GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180
            GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK
Sbjct: 330  GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 389

Query: 181  VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 240
            VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT
Sbjct: 390  VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 449

Query: 241  DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 300
            DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT
Sbjct: 450  DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 509

Query: 301  QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 360
            QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK
Sbjct: 510  QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 569

Query: 361  HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 420
            HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR
Sbjct: 570  HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 629

Query: 421  ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 480
            ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP
Sbjct: 630  ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 689

Query: 481  MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 540
            MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI
Sbjct: 690  MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 749

Query: 541  STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 600
            STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY
Sbjct: 750  STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 809

Query: 601  DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 660
            DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR
Sbjct: 810  DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 869

Query: 661  VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 720
            VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ
Sbjct: 870  VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 929

Query: 721  EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 780
            EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL
Sbjct: 930  EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 989

Query: 781  VSLKKFLDTAFNLQAFEGKTF 801
            VSLKKFLDTAFNLQAFEGKTF
Sbjct: 990  VSLKKFLDTAFNLQAFEGKTF 1010


>gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase
            (lipoamide) isoform 1 precursor [Homo sapiens]
          Length = 1023

 Score = 1396 bits (3613), Expect = 0.0
 Identities = 654/798 (81%), Positives = 733/798 (91%), Gaps = 1/798 (0%)

Query: 1    MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60
            MFIND+EQCQWIRQKFETPG+MQF++EEKRTLLARLVRS RFE+FL RKWSSEKRFGLEG
Sbjct: 223  MFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEG 282

Query: 61   CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120
            CEV+IPALKTIIDKSSE G++ VI+GMPHRGRLNVLANVIRK+LEQIFCQFD KLEAADE
Sbjct: 283  CEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADE 342

Query: 121  GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180
            GSGDVKYHLGMYH RINRVT+RNITLSLVANPSHLEA DPVV GKTKAEQFY GD +GKK
Sbjct: 343  GSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKK 402

Query: 181  VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 240
            VMSIL+HGDAAFAGQG+VYETFHLSDLPSYTT+GTVHVVVNNQIGFTTDPRMARSSPYPT
Sbjct: 403  VMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPT 462

Query: 241  DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 300
            DVARVVNAPIFHVN+DDPEAV+YVC VAAEWR+TF+KDVVVDLVCYRR GHNEMDEPMFT
Sbjct: 463  DVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFT 522

Query: 301  QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 360
            QPLMYKQI +Q PVL+KYA+ L+++G V   E+EEEI+KYD+ICEEA+ RSKD+KILHIK
Sbjct: 523  QPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIK 582

Query: 361  HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 420
            HWLDSPWPGFF +DG+P+SM+CP+TG+ ED+LTHIG+VASSVP+E+F IH GLSRIL+ R
Sbjct: 583  HWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTR 642

Query: 421  ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 480
             +M KNRTVDWALAEYMAFGSLLKEGIH+RLSGQDVERGTFSHRHHVLHDQ VD+RTC+P
Sbjct: 643  GEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIP 702

Query: 481  MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 540
            MNHLWP+QAPYTVCNSSLSEYGVLGFELG+AMASPNALVLWEAQFGDFHNTAQCIIDQFI
Sbjct: 703  MNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFI 762

Query: 541  STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTK-DFEVSQL 599
              GQAKWVR NGIVLLLPHGMEGMGPEHSSARPERFLQM NDD D  P   + +F+++QL
Sbjct: 763  CPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQL 822

Query: 600  YDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQ 659
            YDCNW+VVNCSTP N+FHVLRRQILLPFRKPLIIFTPKSLLRHPEA+SSFD+M+ GT FQ
Sbjct: 823  YDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQ 882

Query: 660  RVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIK 719
            RVIPEDG AA+ PE V+RL+FCTGKVYYDL +ER ++D+  +VAITR+EQ+SPFPFDL+ 
Sbjct: 883  RVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLL 942

Query: 720  QEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTH 779
            +E +KYP AELAWCQEEHKN GYYDY+ PR  T + RA+P+WY GRDPAAAPATGN+ TH
Sbjct: 943  KEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRAKPVWYAGRDPAAAPATGNKKTH 1002

Query: 780  LVSLKKFLDTAFNLQAFE 797
            L  L++ LDTAF+L  F+
Sbjct: 1003 LTELQRLLDTAFDLDVFK 1020


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score =  564 bits (1453), Expect = e-160
 Identities = 333/807 (41%), Positives = 476/807 (58%), Gaps = 51/807 (6%)

Query: 7   EQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIP 66
           ++  W  ++FE      F++EE++ L   ++ S  F+ FLA K+S+ KR+G EG E M+ 
Sbjct: 141 DEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMG 200

Query: 67  ALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGS--GD 124
               ++  S+  GI +VI+GMPHRGRLN+L  +++   E +F +     E  +  S  GD
Sbjct: 201 FFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGD 260

Query: 125 VKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQ------- 177
           V  HL    + +    +  + ++++ NPSHLEAV+PV  GKT+  Q  R D         
Sbjct: 261 VLSHLTSSVD-LYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSA 319

Query: 178 --GKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARS 235
             G +V+ + VHGDA+F GQG+V ETF LS+LP +   G+VH++VNNQ+G+TT     RS
Sbjct: 320 QPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRS 379

Query: 236 SPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMD 295
           S Y +D+ ++V   I HVN D PE V+    +A E++  F KDV++DL+CYR+ GHNE+D
Sbjct: 380 SLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELD 439

Query: 296 EPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKK 355
           EP +T P+MYK I  +  +   YA+ LIA G +T +E  E  + Y       Y +  D  
Sbjct: 440 EPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSY-------YAKLND-H 491

Query: 356 ILHIKHW------LDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKI 409
           + ++ H+      L + W G    + +   +T  +TG+P D+L  +G  +  VP E  ++
Sbjct: 492 LNNMAHYRPPALNLQAHWQGLAQPEAQ---ITTWSTGVPLDLLRFVGMKSVEVPRE-LQM 547

Query: 410 HTGL--SRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHV 467
           H+ L  + +      M     +DWA AE +A GSLL +G +VRLSGQDV RGTFS RH +
Sbjct: 548 HSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAI 607

Query: 468 LHDQEVDRRTCVPMNHLWPDQAPY-TVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFG 526
           +  QE D  T +P+NH+ P+Q  +  V NS LSE  VLGFE G ++ SP  L LWEAQFG
Sbjct: 608 VVCQETD-DTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFG 666

Query: 527 DFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDA 586
           DF N AQ I D FIS G+AKW+  +GIV+LLPHG +G GP+HSS R ERFLQM +   + 
Sbjct: 667 DFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEG 726

Query: 587 YPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAK 646
               T           N  VV+ +TPA YFH+LRRQ++  FRKPLI+ +PK LLR P A 
Sbjct: 727 VDGDT----------VNMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAV 776

Query: 647 SSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEE-KVAIT 705
           S+  +M  GT+F  VI   G ++  P++V+ L+FC+GK +Y LVK+R S   ++   AI 
Sbjct: 777 STLQEMAPGTTFNPVI---GDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAII 833

Query: 706 RLEQISPFPFDLIKQEAEKYPGA-ELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVG 764
           R+E++ PFP D ++QE  KY    +  W QEE +NMG + ++SPRF   L  A  +  VG
Sbjct: 834 RVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQL--ACKLRLVG 891

Query: 765 RDPAAAPATGNRNTHLVSLKKFLDTAF 791
           R P   PA G    HL   +  L   F
Sbjct: 892 RPPLPVPAVGIGTVHLHQHEDILAKTF 918


>gi|51873038 oxoglutarate (alpha-ketoglutarate) dehydrogenase
           (lipoamide) isoform 2 precursor [Homo sapiens]
          Length = 427

 Score =  328 bits (842), Expect = 9e-90
 Identities = 159/181 (87%), Positives = 171/181 (94%)

Query: 1   MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60
           MFIND+EQCQWIRQKFETPG+MQF++EEKRTLLARLVRS RFE+FL RKWSSEKRFGLEG
Sbjct: 223 MFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEG 282

Query: 61  CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120
           CEV+IPALKTIIDKSSE G++ VI+GMPHRGRLNVLANVIRK+LEQIFCQFD KLEAADE
Sbjct: 283 CEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADE 342

Query: 121 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180
           GSGDVKYHLGMYH RINRVT+RNITLSLVANPSHLEA DPVV GKTKAEQFY GD +GKK
Sbjct: 343 GSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKK 402

Query: 181 V 181
           V
Sbjct: 403 V 403


>gi|224586880 Ras protein-specific guanine nucleotide-releasing
           factor 1 isoform 3 [Homo sapiens]
          Length = 1257

 Score = 33.9 bits (76), Expect = 0.61
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 26  SEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVIL 85
           ++ K   L+R++     E    RK  + +R  +EGCE+++   +T + + S + +     
Sbjct: 412 AKSKLEELSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEK 471

Query: 86  GMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHL 129
           G   RGRL  L+  ++K+ E+    F   L     GSG  K HL
Sbjct: 472 GKITRGRLGSLS--LKKEGERQCFLFSKHLIICTRGSGG-KLHL 512


>gi|24797099 Ras protein-specific guanine nucleotide-releasing
           factor 1 isoform 1 [Homo sapiens]
          Length = 1273

 Score = 33.9 bits (76), Expect = 0.61
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 26  SEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVIL 85
           ++ K   L+R++     E    RK  + +R  +EGCE+++   +T + + S + +     
Sbjct: 412 AKSKLEELSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEK 471

Query: 86  GMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHL 129
           G   RGRL  L+  ++K+ E+    F   L     GSG  K HL
Sbjct: 472 GKITRGRLGSLS--LKKEGERQCFLFSKHLIICTRGSGG-KLHL 512


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 9/120 (7%)

Query: 373  VDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWA 432
            V G P  +TC  +G+P   +T +      +P+E   +H  +SR   GR  +++ +     
Sbjct: 1946 VAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAVHGVVSR--GGRLQLSRLQPAQAG 2000

Query: 433  LAEYMAFGS---LLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQA 489
                +A  +     K+ +   L    +     +  HHVL  QEV R  C       PD A
Sbjct: 2001 TYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV-RLDCEADGQPPPDVA 2059


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 9/120 (7%)

Query: 373  VDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWA 432
            V G P  +TC  +G+P   +T +      +P+E   +H  +SR   GR  +++ +     
Sbjct: 3137 VAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAVHGVVSR--GGRLQLSRLQPAQAG 3191

Query: 433  LAEYMAFGS---LLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQA 489
                +A  +     K+ +   L    +     +  HHVL  QEV R  C       PD A
Sbjct: 3192 TYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV-RLDCEADGQPPPDVA 3250


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 9/120 (7%)

Query: 373  VDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWA 432
            V G P  +TC  +G+P   +T +      +P+E   +H  +SR   GR  +++ +     
Sbjct: 1855 VAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAVHGVVSR--GGRLQLSRLQPAQAG 1909

Query: 433  LAEYMAFGS---LLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQA 489
                +A  +     K+ +   L    +     +  HHVL  QEV R  C       PD A
Sbjct: 1910 TYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV-RLDCEADGQPPPDVA 1968


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 30.8 bits (68), Expect = 5.2
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 279 VVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEG-TVTLQEFEEEI 337
           VV+ +VC RRRG    D   +T  L +       P +K Y D    E     ++EF +EI
Sbjct: 559 VVIAIVCNRRRGFERADSE-YTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEI 617


>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
          Length = 4624

 Score = 30.0 bits (66), Expect = 8.9
 Identities = 22/110 (20%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 228  TDPRMARSSPYPTDVARVVNAPI------FHVNADDPEAVIYVCSVAAEWRNTFNKDVVV 281
            +D  M  +    T     VN PI      ++ N  + + ++ + SV +   N+  K+V+ 
Sbjct: 1077 SDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVIT 1136

Query: 282  DLVCYRR------RGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAE 325
             + C++R      +G  E  +   TQ  +  +   Q+   +    ++ AE
Sbjct: 1137 SMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAE 1186


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,484,665
Number of Sequences: 37866
Number of extensions: 1437523
Number of successful extensions: 2860
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2826
Number of HSP's gapped (non-prelim): 30
length of query: 801
length of database: 18,247,518
effective HSP length: 110
effective length of query: 691
effective length of database: 14,082,258
effective search space: 9730840278
effective search space used: 9730840278
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.