Search of human proteins with 221316665

Search of human proteins with 221316665

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221316665 oxoglutarate dehydrogenase-like isoform b [Homo
sapiens]
         (953 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221316665 oxoglutarate dehydrogenase-like isoform b [Homo sap...  1947   0.0  
gi|221316661 oxoglutarate dehydrogenase-like isoform a [Homo sap...  1910   0.0  
gi|221316669 oxoglutarate dehydrogenase-like isoform c [Homo sap...  1642   0.0  
gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...  1528   0.0  
gi|38788380 dehydrogenase E1 and transketolase domain containing...   578   e-165
gi|51873038 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...   461   e-129
gi|224586880 Ras protein-specific guanine nucleotide-releasing f...    34   0.74 
gi|24797099 Ras protein-specific guanine nucleotide-releasing fa...    34   0.74 
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    31   4.8  
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    31   4.8  
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    31   4.8  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...    31   6.3  

>gi|221316665 oxoglutarate dehydrogenase-like isoform b [Homo
           sapiens]
          Length = 953

 Score = 1947 bits (5043), Expect = 0.0
 Identities = 953/953 (100%), Positives = 953/953 (100%)

Query: 1   MSQLRLLPSRLGVQAARLLAAHDVPVFGWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWL 60
           MSQLRLLPSRLGVQAARLLAAHDVPVFGWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWL
Sbjct: 1   MSQLRLLPSRLGVQAARLLAAHDVPVFGWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWL 60

Query: 61  ENPQSVHKIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPT 120
           ENPQSVHKIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPT
Sbjct: 61  ENPQSVHKIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPT 120

Query: 121 TTFIGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEE 180
           TTFIGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEE
Sbjct: 121 TTFIGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEE 180

Query: 181 KRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMP 240
           KRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMP
Sbjct: 181 KRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMP 240

Query: 241 HRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSL 300
           HRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSL
Sbjct: 241 HRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSL 300

Query: 301 VANPSHLEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLP 360
           VANPSHLEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLP
Sbjct: 301 VANPSHLEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLP 360

Query: 361 SYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVA 420
           SYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVA
Sbjct: 361 SYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVA 420

Query: 421 AEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTV 480
           AEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTV
Sbjct: 421 AEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTV 480

Query: 481 TLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIP 540
           TLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIP
Sbjct: 481 TLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIP 540

Query: 541 EDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIH 600
           EDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIH
Sbjct: 541 EDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIH 600

Query: 601 VRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFEL 660
           VRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFEL
Sbjct: 601 VRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFEL 660

Query: 661 GYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEH 720
           GYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEH
Sbjct: 661 GYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEH 720

Query: 721 SSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFR 780
           SSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFR
Sbjct: 721 SSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFR 780

Query: 781 KPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYD 840
           KPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYD
Sbjct: 781 KPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYD 840

Query: 841 LVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISP 900
           LVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISP
Sbjct: 841 LVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISP 900

Query: 901 RFMTILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF 953
           RFMTILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF
Sbjct: 901 RFMTILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF 953


>gi|221316661 oxoglutarate dehydrogenase-like isoform a [Homo sapiens]
          Length = 1010

 Score = 1910 bits (4949), Expect = 0.0
 Identities = 950/1010 (94%), Positives = 951/1010 (94%), Gaps = 57/1010 (5%)

Query: 1    MSQLRLLPSRLGVQAARLLAAHDVPVFGWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWL 60
            MSQLRLLPSRLGVQAARLLAAHDVPVFGWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWL
Sbjct: 1    MSQLRLLPSRLGVQAARLLAAHDVPVFGWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWL 60

Query: 61   EN----------------------------PQSVHK------------------------ 68
            EN                            P  VH+                        
Sbjct: 61   ENPQSVHKSWDSFFREASEEAFSGSAQPRPPSVVHESRSAVSSRTKTSKLVEDHLAVQSL 120

Query: 69   -----IRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTF 123
                 IRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTF
Sbjct: 121  IRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTF 180

Query: 124  IGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRT 183
            IGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRT
Sbjct: 181  IGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRT 240

Query: 184  LLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRG 243
            LLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRG
Sbjct: 241  LLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRG 300

Query: 244  RLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVAN 303
            RLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVAN
Sbjct: 301  RLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVAN 360

Query: 304  PSHLEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYT 363
            PSHLEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYT
Sbjct: 361  PSHLEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYT 420

Query: 364  TNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEW 423
            TNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEW
Sbjct: 421  TNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEW 480

Query: 424  RNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQ 483
            RNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQ
Sbjct: 481  RNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQ 540

Query: 484  EFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIPEDM 543
            EFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIPEDM
Sbjct: 541  EFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIPEDM 600

Query: 544  LTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRL 603
            LTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRL
Sbjct: 601  LTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRL 660

Query: 604  SGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYA 663
            SGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYA
Sbjct: 661  SGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYA 720

Query: 664  MASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSA 723
            MASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSA
Sbjct: 721  MASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSA 780

Query: 724  RPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPL 783
            RPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPL
Sbjct: 781  RPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPL 840

Query: 784  IIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVK 843
            IIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVK
Sbjct: 841  IIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVK 900

Query: 844  ERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFM 903
            ERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFM
Sbjct: 901  ERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFM 960

Query: 904  TILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF 953
            TILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF
Sbjct: 961  TILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF 1010


>gi|221316669 oxoglutarate dehydrogenase-like isoform c [Homo
           sapiens]
          Length = 801

 Score = 1642 bits (4251), Expect = 0.0
 Identities = 801/801 (100%), Positives = 801/801 (100%)

Query: 153 MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 212
           MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG
Sbjct: 1   MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60

Query: 213 CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 272
           CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE
Sbjct: 61  CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120

Query: 273 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 332
           GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK
Sbjct: 121 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180

Query: 333 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 392
           VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT
Sbjct: 181 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 240

Query: 393 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 452
           DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT
Sbjct: 241 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 300

Query: 453 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 512
           QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK
Sbjct: 301 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 360

Query: 513 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 572
           HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR
Sbjct: 361 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 420

Query: 573 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 632
           ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP
Sbjct: 421 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 480

Query: 633 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 692
           MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI
Sbjct: 481 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 540

Query: 693 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 752
           STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY
Sbjct: 541 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLY 600

Query: 753 DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 812
           DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR
Sbjct: 601 DCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQR 660

Query: 813 VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 872
           VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ
Sbjct: 661 VIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQ 720

Query: 873 EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 932
           EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL
Sbjct: 721 EAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHL 780

Query: 933 VSLKKFLDTAFNLQAFEGKTF 953
           VSLKKFLDTAFNLQAFEGKTF
Sbjct: 781 VSLKKFLDTAFNLQAFEGKTF 801


>gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase
            (lipoamide) isoform 1 precursor [Homo sapiens]
          Length = 1023

 Score = 1528 bits (3957), Expect = 0.0
 Identities = 719/884 (81%), Positives = 807/884 (91%), Gaps = 1/884 (0%)

Query: 67   HKIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGG 126
            ++IRGHHVAQLDPLGILDADLDS VP+D+I++ DKL FY L E+DLDK F LPTTTFIGG
Sbjct: 137  YQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGG 196

Query: 127  SENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLA 186
             E+ L LREIIRRLE  YCQHIG+EFMFIND+EQCQWIRQKFETPG+MQF++EEKRTLLA
Sbjct: 197  QESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLA 256

Query: 187  RLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLN 246
            RLVRS RFE+FL RKWSSEKRFGLEGCEV+IPALKTIIDKSSE G++ VI+GMPHRGRLN
Sbjct: 257  RLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLN 316

Query: 247  VLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSH 306
            VLANVIRK+LEQIFCQFD KLEAADEGSGDVKYHLGMYH RINRVT+RNITLSLVANPSH
Sbjct: 317  VLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSH 376

Query: 307  LEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNG 366
            LEA DPVV GKTKAEQFY GD +GKKVMSIL+HGDAAFAGQG+VYETFHLSDLPSYTT+G
Sbjct: 377  LEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHG 436

Query: 367  TVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNT 426
            TVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVN+DDPEAV+YVC VAAEWR+T
Sbjct: 437  TVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRST 496

Query: 427  FNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFE 486
            F+KDVVVDLVCYRR GHNEMDEPMFTQPLMYKQI +Q PVL+KYA+ L+++G V   E+E
Sbjct: 497  FHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYE 556

Query: 487  EEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTH 546
            EEI+KYD+ICEEA+ RSKD+KILHIKHWLDSPWPGFF +DG+P+SM+CP+TG+ ED+LTH
Sbjct: 557  EEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTH 616

Query: 547  IGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQ 606
            IG+VASSVP+E+F IH GLSRIL+ R +M KNRTVDWALAEYMAFGSLLKEGIH+RLSGQ
Sbjct: 617  IGNVASSVPVENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQ 676

Query: 607  DVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMAS 666
            DVERGTFSHRHHVLHDQ VD+RTC+PMNHLWP+QAPYTVCNSSLSEYGVLGFELG+AMAS
Sbjct: 677  DVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMAS 736

Query: 667  PNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPE 726
            PNALVLWEAQFGDFHNTAQCIIDQFI  GQAKWVR NGIVLLLPHGMEGMGPEHSSARPE
Sbjct: 737  PNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPE 796

Query: 727  RFLQMSNDDSDAYPAFTK-DFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLII 785
            RFLQM NDD D  P   + +F+++QLYDCNW+VVNCSTP N+FHVLRRQILLPFRKPLII
Sbjct: 797  RFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLII 856

Query: 786  FTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKER 845
            FTPKSLLRHPEA+SSFD+M+ GT FQRVIPEDG AA+ PE V+RL+FCTGKVYYDL +ER
Sbjct: 857  FTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRER 916

Query: 846  SSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTI 905
             ++D+  +VAITR+EQ+SPFPFDL+ +E +KYP AELAWCQEEHKN GYYDY+ PR  T 
Sbjct: 917  KARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTT 976

Query: 906  LRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFE 949
            + RA+P+WY GRDPAAAPATGN+ THL  L++ LDTAF+L  F+
Sbjct: 977  ISRAKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFK 1020


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score =  578 bits (1491), Expect = e-165
 Identities = 353/901 (39%), Positives = 512/901 (56%), Gaps = 65/901 (7%)

Query: 65  SVHKIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTFI 124
           +V+   GH  A+++PL    A L++ VP             ++Q      +    T   +
Sbjct: 61  TVYCEHGHKAAKINPLFTGQALLEN-VP-------------EIQALVQTLQGPFHTAGLL 106

Query: 125 GGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTL 184
              +   SL E++  L   YC  I +E   +   ++  W  ++FE      F++EE++ L
Sbjct: 107 NMGKEEASLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHL 166

Query: 185 LARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGR 244
              ++ S  F+ FLA K+S+ KR+G EG E M+     ++  S+  GI +VI+GMPHRGR
Sbjct: 167 SKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGR 226

Query: 245 LNVLANVIRKDLEQIFCQFDPKLEAADEGS--GDVKYHLGMYHERINRVTNRNITLSLVA 302
           LN+L  +++   E +F +     E  +  S  GDV  HL    + +    +  + ++++ 
Sbjct: 227 LNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVD-LYFGAHHPLHVTMLP 285

Query: 303 NPSHLEAVDPVVQGKTKAEQFYRGDAQ---------GKKVMSILVHGDAAFAGQGVVYET 353
           NPSHLEAV+PV  GKT+  Q  R D           G +V+ + VHGDA+F GQG+V ET
Sbjct: 286 NPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPET 345

Query: 354 FHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAV 413
           F LS+LP +   G+VH++VNNQ+G+TT     RSS Y +D+ ++V   I HVN D PE V
Sbjct: 346 FTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEV 405

Query: 414 IYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADK 473
           +    +A E++  F KDV++DL+CYR+ GHNE+DEP +T P+MYK I  +  +   YA+ 
Sbjct: 406 VRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEH 465

Query: 474 LIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHW------LDSPWPGFFNVDG 527
           LIA G +T +E  E  + Y       Y +  D  + ++ H+      L + W G    + 
Sbjct: 466 LIAGGLMTQEEVSEIKSSY-------YAKLND-HLNNMAHYRPPALNLQAHWQGLAQPEA 517

Query: 528 EPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGL--SRILRGRADMTKNRTVDWAL 585
           +   +T  +TG+P D+L  +G  +  VP E  ++H+ L  + +      M     +DWA 
Sbjct: 518 Q---ITTWSTGVPLDLLRFVGMKSVEVPRE-LQMHSHLLKTHVQSRMEKMMDGIKLDWAT 573

Query: 586 AEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPY-T 644
           AE +A GSLL +G +VRLSGQDV RGTFS RH ++  QE D  T +P+NH+ P+Q  +  
Sbjct: 574 AEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETD-DTYIPLNHMDPNQKGFLE 632

Query: 645 VCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNG 704
           V NS LSE  VLGFE G ++ SP  L LWEAQFGDF N AQ I D FIS G+AKW+  +G
Sbjct: 633 VSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSG 692

Query: 705 IVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTP 764
           IV+LLPHG +G GP+HSS R ERFLQM +   +     T           N  VV+ +TP
Sbjct: 693 IVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDT----------VNMFVVHPTTP 742

Query: 765 ANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAP 824
           A YFH+LRRQ++  FRKPLI+ +PK LLR P A S+  +M  GT+F  VI   G ++  P
Sbjct: 743 AQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVI---GDSSVDP 799

Query: 825 EQVQRLIFCTGKVYYDLVKERSSQDLEE-KVAITRLEQISPFPFDLIKQEAEKYPGA-EL 882
           ++V+ L+FC+GK +Y LVK+R S   ++   AI R+E++ PFP D ++QE  KY    + 
Sbjct: 800 KKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDH 859

Query: 883 AWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTA 942
            W QEE +NMG + ++SPRF   L  A  +  VGR P   PA G    HL   +  L   
Sbjct: 860 IWSQEEPQNMGPWSFVSPRFEKQL--ACKLRLVGRPPLPVPAVGIGTVHLHQHEDILAKT 917

Query: 943 F 943
           F
Sbjct: 918 F 918


>gi|51873038 oxoglutarate (alpha-ketoglutarate) dehydrogenase
           (lipoamide) isoform 2 precursor [Homo sapiens]
          Length = 427

 Score =  461 bits (1186), Expect = e-129
 Identities = 224/267 (83%), Positives = 245/267 (91%)

Query: 67  HKIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGG 126
           ++IRGHHVAQLDPLGILDADLDS VP+D+I++ DKL FY L E+DLDK F LPTTTFIGG
Sbjct: 137 YQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGG 196

Query: 127 SENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLA 186
            E+ L LREIIRRLE  YCQHIG+EFMFIND+EQCQWIRQKFETPG+MQF++EEKRTLLA
Sbjct: 197 QESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLA 256

Query: 187 RLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLN 246
           RLVRS RFE+FL RKWSSEKRFGLEGCEV+IPALKTIIDKSSE G++ VI+GMPHRGRLN
Sbjct: 257 RLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLN 316

Query: 247 VLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSH 306
           VLANVIRK+LEQIFCQFD KLEAADEGSGDVKYHLGMYH RINRVT+RNITLSLVANPSH
Sbjct: 317 VLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSH 376

Query: 307 LEAVDPVVQGKTKAEQFYRGDAQGKKV 333
           LEA DPVV GKTKAEQFY GD +GKKV
Sbjct: 377 LEAADPVVMGKTKAEQFYCGDTEGKKV 403


>gi|224586880 Ras protein-specific guanine nucleotide-releasing
           factor 1 isoform 3 [Homo sapiens]
          Length = 1257

 Score = 33.9 bits (76), Expect = 0.74
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 178 SEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVIL 237
           ++ K   L+R++     E    RK  + +R  +EGCE+++   +T + + S + +     
Sbjct: 412 AKSKLEELSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEK 471

Query: 238 GMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHL 281
           G   RGRL  L+  ++K+ E+    F   L     GSG  K HL
Sbjct: 472 GKITRGRLGSLS--LKKEGERQCFLFSKHLIICTRGSGG-KLHL 512


>gi|24797099 Ras protein-specific guanine nucleotide-releasing
           factor 1 isoform 1 [Homo sapiens]
          Length = 1273

 Score = 33.9 bits (76), Expect = 0.74
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 178 SEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVIL 237
           ++ K   L+R++     E    RK  + +R  +EGCE+++   +T + + S + +     
Sbjct: 412 AKSKLEELSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEK 471

Query: 238 GMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHL 281
           G   RGRL  L+  ++K+ E+    F   L     GSG  K HL
Sbjct: 472 GKITRGRLGSLS--LKKEGERQCFLFSKHLIICTRGSGG-KLHL 512


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 31.2 bits (69), Expect = 4.8
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 9/120 (7%)

Query: 525  VDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWA 584
            V G P  +TC  +G+P   +T +      +P+E   +H  +SR   GR  +++ +     
Sbjct: 1946 VAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAVHGVVSR--GGRLQLSRLQPAQAG 2000

Query: 585  LAEYMAFGS---LLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQA 641
                +A  +     K+ +   L    +     +  HHVL  QEV R  C       PD A
Sbjct: 2001 TYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV-RLDCEADGQPPPDVA 2059


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 31.2 bits (69), Expect = 4.8
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 9/120 (7%)

Query: 525  VDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWA 584
            V G P  +TC  +G+P   +T +      +P+E   +H  +SR   GR  +++ +     
Sbjct: 3137 VAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAVHGVVSR--GGRLQLSRLQPAQAG 3191

Query: 585  LAEYMAFGS---LLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQA 641
                +A  +     K+ +   L    +     +  HHVL  QEV R  C       PD A
Sbjct: 3192 TYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV-RLDCEADGQPPPDVA 3250


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 31.2 bits (69), Expect = 4.8
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 9/120 (7%)

Query: 525  VDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWA 584
            V G P  +TC  +G+P   +T +      +P+E   +H  +SR   GR  +++ +     
Sbjct: 1855 VAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAVHGVVSR--GGRLQLSRLQPAQAG 1909

Query: 585  LAEYMAFGS---LLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQA 641
                +A  +     K+ +   L    +     +  HHVL  QEV R  C       PD A
Sbjct: 1910 TYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV-RLDCEADGQPPPDVA 1968


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 30.8 bits (68), Expect = 6.3
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 431 VVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEG-TVTLQEFEEEI 489
           VV+ +VC RRRG    D   +T  L +       P +K Y D    E     ++EF +EI
Sbjct: 559 VVIAIVCNRRRGFERADSE-YTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEI 617


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,617,877
Number of Sequences: 37866
Number of extensions: 1742583
Number of successful extensions: 3613
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3577
Number of HSP's gapped (non-prelim): 31
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.