Guide to the Human Genome
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Search of human proteins with 21945064

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21945064 septin 10 isoform 1 [Homo sapiens]
         (454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21945064 septin 10 isoform 1 [Homo sapiens]                        904   0.0  
gi|30795193 septin 10 isoform 2 [Homo sapiens]                        845   0.0  
gi|8922712 septin 11 [Homo sapiens]                                   644   0.0  
gi|149363689 septin 8 isoform a [Homo sapiens]                        629   e-180
gi|149363661 septin 8 isoform b [Homo sapiens]                        629   e-180
gi|21361478 septin 6 isoform B [Homo sapiens]                         629   e-180
gi|149363638 septin 8 isoform c [Homo sapiens]                        628   e-180
gi|22035581 septin 6 isoform D [Homo sapiens]                         627   e-180
gi|22035579 septin 6 isoform A [Homo sapiens]                         627   e-180
gi|22035577 septin 6 isoform A [Homo sapiens]                         627   e-180
gi|153252198 septin 14 [Homo sapiens]                                 617   e-177
gi|149363664 septin 8 isoform d [Homo sapiens]                        556   e-158
gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]          309   3e-84
gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]          309   3e-84
gi|156602655 septin 3 isoform A [Homo sapiens]                        254   1e-67
gi|156602653 septin 3 isoform B [Homo sapiens]                        254   1e-67
gi|9945439 septin 5 [Homo sapiens]                                    253   3e-67
gi|4758942 septin 4 isoform 1 [Homo sapiens]                          252   6e-67
gi|17986247 septin 4 isoform 3 [Homo sapiens]                         252   6e-67
gi|164698504 septin 9 isoform f [Homo sapiens]                        247   2e-65
gi|164698502 septin 9 isoform d [Homo sapiens]                        247   2e-65
gi|164698500 septin 9 isoform e [Homo sapiens]                        247   2e-65
gi|164698498 septin 9 isoform b [Homo sapiens]                        247   2e-65
gi|164698496 septin 9 isoform e [Homo sapiens]                        247   2e-65
gi|164698494 septin 9 isoform a [Homo sapiens]                        247   2e-65
gi|116256489 septin 9 isoform c [Homo sapiens]                        247   2e-65
gi|56549640 septin 2 [Homo sapiens]                                   245   7e-65
gi|56549638 septin 2 [Homo sapiens]                                   245   7e-65
gi|56549636 septin 2 [Homo sapiens]                                   245   7e-65
gi|4758158 septin 2 [Homo sapiens]                                    245   7e-65

>gi|21945064 septin 10 isoform 1 [Homo sapiens]
          Length = 454

 Score =  904 bits (2337), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 1   MASSEVARHLLFQSHMATKTTCMSSQGSDDEQIKRENIRSLTMSGHVGFESLPDQLVNRS 60
           MASSEVARHLLFQSHMATKTTCMSSQGSDDEQIKRENIRSLTMSGHVGFESLPDQLVNRS
Sbjct: 1   MASSEVARHLLFQSHMATKTTCMSSQGSDDEQIKRENIRSLTMSGHVGFESLPDQLVNRS 60

Query: 61  IQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLK 120
           IQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLK
Sbjct: 61  IQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLK 120

Query: 121 LTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFIS 180
           LTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFIS
Sbjct: 121 LTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFIS 180

Query: 181 PTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFP 240
           PTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFP
Sbjct: 181 PTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFP 240

Query: 241 TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLRE 300
           TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLRE
Sbjct: 241 TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLRE 300

Query: 301 MLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQ 360
           MLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQ
Sbjct: 301 MLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQ 360

Query: 361 RKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAF 420
           RKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAF
Sbjct: 361 RKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAF 420

Query: 421 SKKKATSEIFHSQSFLATGSNLRKDKDRKNSNFL 454
           SKKKATSEIFHSQSFLATGSNLRKDKDRKNSNFL
Sbjct: 421 SKKKATSEIFHSQSFLATGSNLRKDKDRKNSNFL 454


>gi|30795193 septin 10 isoform 2 [Homo sapiens]
          Length = 431

 Score =  845 bits (2184), Expect = 0.0
 Identities = 431/454 (94%), Positives = 431/454 (94%), Gaps = 23/454 (5%)

Query: 1   MASSEVARHLLFQSHMATKTTCMSSQGSDDEQIKRENIRSLTMSGHVGFESLPDQLVNRS 60
           MASSEVARHL                       KRENIRSLTMSGHVGFESLPDQLVNRS
Sbjct: 1   MASSEVARHL-----------------------KRENIRSLTMSGHVGFESLPDQLVNRS 37

Query: 61  IQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLK 120
           IQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLK
Sbjct: 38  IQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLK 97

Query: 121 LTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFIS 180
           LTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFIS
Sbjct: 98  LTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFIS 157

Query: 181 PTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFP 240
           PTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFP
Sbjct: 158 PTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFP 217

Query: 241 TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLRE 300
           TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLRE
Sbjct: 218 TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLRE 277

Query: 301 MLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQ 360
           MLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQ
Sbjct: 278 MLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQ 337

Query: 361 RKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAF 420
           RKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAF
Sbjct: 338 RKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAF 397

Query: 421 SKKKATSEIFHSQSFLATGSNLRKDKDRKNSNFL 454
           SKKKATSEIFHSQSFLATGSNLRKDKDRKNSNFL
Sbjct: 398 SKKKATSEIFHSQSFLATGSNLRKDKDRKNSNFL 431


>gi|8922712 septin 11 [Homo sapiens]
          Length = 429

 Score =  644 bits (1660), Expect = 0.0
 Identities = 311/418 (74%), Positives = 368/418 (88%)

Query: 36  ENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE 95
           E +R+L++SGHVGF+SLPDQLVN+S  QGFCFNILCVGETGIGKSTL+DTLFNT FE   
Sbjct: 11  EELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDP 70

Query: 96  SSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQ 155
           ++H  P V+LKA++YELQESNV+LKLTIV+TVGFGDQINK++SY+PIV+YIDAQFEAYLQ
Sbjct: 71  ATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQ 130

Query: 156 EELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSK 215
           EELKIKRSLF YHD+RIH CLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKADT++K
Sbjct: 131 EELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAK 190

Query: 216 TELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
            EL KFK K+MSELVSNGVQIYQFPTD++T+A++NA M+  LPFAVVGS +EVK+GNKM 
Sbjct: 191 NELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMA 250

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           KARQYPWGVVQVENENHCDFVKLREMLI  NMEDLREQTHTRHYELYRRCKLEEMGF D 
Sbjct: 251 KARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDT 310

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
            P++KP S+QETYEAKR+EF GE Q+KEEEM+QMFV RVKEKEA LKEAE+EL  KF+ L
Sbjct: 311 DPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLL 370

Query: 396 KRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGSNLRKDKDRKNSNF 453
           KR HQEE+ K+E+K++ LEEE+  F KKKA +++  SQ+  +     +KDKD+KN++F
Sbjct: 371 KRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNASF 428


>gi|149363689 septin 8 isoform a [Homo sapiens]
          Length = 483

 Score =  629 bits (1623), Expect = e-180
 Identities = 312/413 (75%), Positives = 358/413 (86%), Gaps = 1/413 (0%)

Query: 39  RSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSH 98
           RSL++ GHVGF+SLPDQLV++S+ QGF FNILCVGETGIGKSTL++TLFNT FE  E+SH
Sbjct: 17  RSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASH 76

Query: 99  FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEEL 158
               V+L+ QTY+LQESNVQLKLTIV+ VGFGDQINK+ESY+PIVDYIDAQFE YLQEEL
Sbjct: 77  HEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEEL 136

Query: 159 KIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTEL 218
           KI+RSLF YHD+RIHVCLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKADT+SK+EL
Sbjct: 137 KIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSEL 196

Query: 219 QKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKAR 278
            KFKIK+M ELVSNGVQIYQFPTDD+ +A++NA MN  LPFAVVGS +EVKVGNK+V+AR
Sbjct: 197 HKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRAR 256

Query: 279 QYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPE 338
           QYPWGVVQVENENHCDFVKLREMLI  NMEDLREQTH+RHYELYRRCKLEEMGF D   +
Sbjct: 257 QYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGD 316

Query: 339 NKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRL 398
           ++P S+QETYEAKR EF  E QRKEEEM+QMFV +VKE E  LKE EREL  KFEHLKR+
Sbjct: 317 SQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRV 376

Query: 399 HQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGSN-LRKDKDRKN 450
           HQEE+ K+EEKRR LEEE  AF+++KA  E   SQ+  AT    LRKDKD+KN
Sbjct: 377 HQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKN 429


>gi|149363661 septin 8 isoform b [Homo sapiens]
          Length = 429

 Score =  629 bits (1623), Expect = e-180
 Identities = 312/413 (75%), Positives = 358/413 (86%), Gaps = 1/413 (0%)

Query: 39  RSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSH 98
           RSL++ GHVGF+SLPDQLV++S+ QGF FNILCVGETGIGKSTL++TLFNT FE  E+SH
Sbjct: 17  RSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASH 76

Query: 99  FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEEL 158
               V+L+ QTY+LQESNVQLKLTIV+ VGFGDQINK+ESY+PIVDYIDAQFE YLQEEL
Sbjct: 77  HEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEEL 136

Query: 159 KIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTEL 218
           KI+RSLF YHD+RIHVCLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKADT+SK+EL
Sbjct: 137 KIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSEL 196

Query: 219 QKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKAR 278
            KFKIK+M ELVSNGVQIYQFPTDD+ +A++NA MN  LPFAVVGS +EVKVGNK+V+AR
Sbjct: 197 HKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRAR 256

Query: 279 QYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPE 338
           QYPWGVVQVENENHCDFVKLREMLI  NMEDLREQTH+RHYELYRRCKLEEMGF D   +
Sbjct: 257 QYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGD 316

Query: 339 NKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRL 398
           ++P S+QETYEAKR EF  E QRKEEEM+QMFV +VKE E  LKE EREL  KFEHLKR+
Sbjct: 317 SQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRV 376

Query: 399 HQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGSN-LRKDKDRKN 450
           HQEE+ K+EEKRR LEEE  AF+++KA  E   SQ+  AT    LRKDKD+KN
Sbjct: 377 HQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKN 429


>gi|21361478 septin 6 isoform B [Homo sapiens]
          Length = 434

 Score =  629 bits (1622), Expect = e-180
 Identities = 301/420 (71%), Positives = 368/420 (87%), Gaps = 1/420 (0%)

Query: 36  ENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE 95
           E  R++ ++GHVGF+SLPDQLVN+S+ QGFCFNILCVGETG+GKSTL+DTLFNT FE   
Sbjct: 12  EGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP 71

Query: 96  SSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQ 155
           ++H  P V+L++ TY+LQESNV+LKLTIV+TVGFGDQINKE+SY+PIV++IDAQFEAYLQ
Sbjct: 72  ATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQ 131

Query: 156 EELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSK 215
           EELKI+R L TYHDSRIHVCLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKAD +SK
Sbjct: 132 EELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISK 191

Query: 216 TELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           +EL KFKIK+ SELVSNGVQIYQFPTDD+++A++N  MN  LPFAV+GS +E+K+GNKM+
Sbjct: 192 SELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMM 251

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           +ARQYPWG VQVENE HCDFVKLREMLI  NMEDLREQTHTRHYELYRRCKLEEMGF D 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDT 311

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
            P++KP S+QETYEAKR+EF GE Q+KEEEM+QMFVQRVKEKEA LKEAE+EL  KF+ L
Sbjct: 312 DPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRL 371

Query: 396 KRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGS-NLRKDKDRKNSNFL 454
           K+LHQ+E+ KLE+K++ L++E+ AF ++K  +E+  SQ   A GS  L++DK++KN+ +L
Sbjct: 372 KKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKNNPWL 431


>gi|149363638 septin 8 isoform c [Homo sapiens]
          Length = 442

 Score =  628 bits (1619), Expect = e-180
 Identities = 311/415 (74%), Positives = 359/415 (86%), Gaps = 1/415 (0%)

Query: 39  RSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSH 98
           RSL++ GHVGF+SLPDQLV++S+ QGF FNILCVGETGIGKSTL++TLFNT FE  E+SH
Sbjct: 17  RSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASH 76

Query: 99  FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEEL 158
               V+L+ QTY+LQESNVQLKLTIV+ VGFGDQINK+ESY+PIVDYIDAQFE YLQEEL
Sbjct: 77  HEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEEL 136

Query: 159 KIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTEL 218
           KI+RSLF YHD+RIHVCLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKADT+SK+EL
Sbjct: 137 KIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSEL 196

Query: 219 QKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKAR 278
            KFKIK+M ELVSNGVQIYQFPTDD+ +A++NA MN  LPFAVVGS +EVKVGNK+V+AR
Sbjct: 197 HKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRAR 256

Query: 279 QYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPE 338
           QYPWGVVQVENENHCDFVKLREMLI  NMEDLREQTH+RHYELYRRCKLEEMGF D   +
Sbjct: 257 QYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGD 316

Query: 339 NKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRL 398
           ++P S+QETYEAKR EF  E QRKEEEM+QMFV +VKE E  LKE EREL  KFEHLKR+
Sbjct: 317 SQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRV 376

Query: 399 HQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGSN-LRKDKDRKNSN 452
           HQEE+ K+EEKRR LEEE  AF+++KA  E   SQ+  AT    LRKDKD+K ++
Sbjct: 377 HQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKKAS 431


>gi|22035581 septin 6 isoform D [Homo sapiens]
          Length = 429

 Score =  627 bits (1618), Expect = e-180
 Identities = 300/416 (72%), Positives = 365/416 (87%), Gaps = 1/416 (0%)

Query: 36  ENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE 95
           E  R++ ++GHVGF+SLPDQLVN+S+ QGFCFNILCVGETG+GKSTL+DTLFNT FE   
Sbjct: 12  EGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP 71

Query: 96  SSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQ 155
           ++H  P V+L++ TY+LQESNV+LKLTIV+TVGFGDQINKE+SY+PIV++IDAQFEAYLQ
Sbjct: 72  ATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQ 131

Query: 156 EELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSK 215
           EELKI+R L TYHDSRIHVCLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKAD +SK
Sbjct: 132 EELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISK 191

Query: 216 TELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           +EL KFKIK+ SELVSNGVQIYQFPTDD+++A++N  MN  LPFAV+GS +E+K+GNKM+
Sbjct: 192 SELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMM 251

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           +ARQYPWG VQVENE HCDFVKLREMLI  NMEDLREQTHTRHYELYRRCKLEEMGF D 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDT 311

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
            P++KP S+QETYEAKR+EF GE Q+KEEEM+QMFVQRVKEKEA LKEAE+EL  KF+ L
Sbjct: 312 DPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRL 371

Query: 396 KRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGS-NLRKDKDRKN 450
           K+LHQ+E+ KLE+K++ L++E+ AF ++K  +E+  SQ   A GS  L++DK++KN
Sbjct: 372 KKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKN 427


>gi|22035579 septin 6 isoform A [Homo sapiens]
          Length = 427

 Score =  627 bits (1618), Expect = e-180
 Identities = 300/416 (72%), Positives = 365/416 (87%), Gaps = 1/416 (0%)

Query: 36  ENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE 95
           E  R++ ++GHVGF+SLPDQLVN+S+ QGFCFNILCVGETG+GKSTL+DTLFNT FE   
Sbjct: 12  EGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP 71

Query: 96  SSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQ 155
           ++H  P V+L++ TY+LQESNV+LKLTIV+TVGFGDQINKE+SY+PIV++IDAQFEAYLQ
Sbjct: 72  ATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQ 131

Query: 156 EELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSK 215
           EELKI+R L TYHDSRIHVCLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKAD +SK
Sbjct: 132 EELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISK 191

Query: 216 TELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           +EL KFKIK+ SELVSNGVQIYQFPTDD+++A++N  MN  LPFAV+GS +E+K+GNKM+
Sbjct: 192 SELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMM 251

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           +ARQYPWG VQVENE HCDFVKLREMLI  NMEDLREQTHTRHYELYRRCKLEEMGF D 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDT 311

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
            P++KP S+QETYEAKR+EF GE Q+KEEEM+QMFVQRVKEKEA LKEAE+EL  KF+ L
Sbjct: 312 DPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRL 371

Query: 396 KRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGS-NLRKDKDRKN 450
           K+LHQ+E+ KLE+K++ L++E+ AF ++K  +E+  SQ   A GS  L++DK++KN
Sbjct: 372 KKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKN 427


>gi|22035577 septin 6 isoform A [Homo sapiens]
          Length = 427

 Score =  627 bits (1618), Expect = e-180
 Identities = 300/416 (72%), Positives = 365/416 (87%), Gaps = 1/416 (0%)

Query: 36  ENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE 95
           E  R++ ++GHVGF+SLPDQLVN+S+ QGFCFNILCVGETG+GKSTL+DTLFNT FE   
Sbjct: 12  EGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP 71

Query: 96  SSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQ 155
           ++H  P V+L++ TY+LQESNV+LKLTIV+TVGFGDQINKE+SY+PIV++IDAQFEAYLQ
Sbjct: 72  ATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQ 131

Query: 156 EELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSK 215
           EELKI+R L TYHDSRIHVCLYFI+PTGHSLK+LDL+TMK LDSKVNIIP+IAKAD +SK
Sbjct: 132 EELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISK 191

Query: 216 TELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           +EL KFKIK+ SELVSNGVQIYQFPTDD+++A++N  MN  LPFAV+GS +E+K+GNKM+
Sbjct: 192 SELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMM 251

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           +ARQYPWG VQVENE HCDFVKLREMLI  NMEDLREQTHTRHYELYRRCKLEEMGF D 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDT 311

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
            P++KP S+QETYEAKR+EF GE Q+KEEEM+QMFVQRVKEKEA LKEAE+EL  KF+ L
Sbjct: 312 DPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRL 371

Query: 396 KRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGS-NLRKDKDRKN 450
           K+LHQ+E+ KLE+K++ L++E+ AF ++K  +E+  SQ   A GS  L++DK++KN
Sbjct: 372 KKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKN 427


>gi|153252198 septin 14 [Homo sapiens]
          Length = 432

 Score =  617 bits (1592), Expect = e-177
 Identities = 309/435 (71%), Positives = 364/435 (83%), Gaps = 5/435 (1%)

Query: 16  MATKTTCMSSQ-GSDDEQIKRENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGE 74
           MA +T  M +Q  +D +  K  NIR LT  GH GFE LP+QLV+RSI+QGF FNILCVGE
Sbjct: 1   MAERTMAMPTQIPADGDTQKENNIRCLTTIGHFGFECLPNQLVSRSIRQGFTFNILCVGE 60

Query: 75  TGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQIN 134
           TGIGKSTLIDTLFNTN +D +SSHF  NV L+ QTYELQESNVQLKLT+V TVG+GDQI+
Sbjct: 61  TGIGKSTLIDTLFNTNLKDNKSSHFYSNVGLQIQTYELQESNVQLKLTVVETVGYGDQID 120

Query: 135 KEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTM 194
           KE SYQPIVDYIDAQFEAYLQEELKIKRSLF YHDSR+HVCLYFISPTGHSLK+LDLLTM
Sbjct: 121 KEASYQPIVDYIDAQFEAYLQEELKIKRSLFEYHDSRVHVCLYFISPTGHSLKSLDLLTM 180

Query: 195 KNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMN 254
           KNLDSKVNIIP+IAKADT+SK +LQ FK K+MSEL+SNG+QIYQ PTD++T A+ N++++
Sbjct: 181 KNLDSKVNIIPLIAKADTISKNDLQTFKNKIMSELISNGIQIYQLPTDEETAAQANSSVS 240

Query: 255 GQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQT 314
           G LPFAVVGS DEVKVG +MV+ R YPWGV+QVENENHCDFVKLR+ML+CTNME+L+E+T
Sbjct: 241 GLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKT 300

Query: 315 HTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRV 374
           HT+HYE YR  KL++MGFTDVGP N+PVS QE +EAKR EF+ + QR+EEE+KQ F+QRV
Sbjct: 301 HTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQRFMQRV 360

Query: 375 KEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQS 434
           KEKEA  KEAE+ELQ KFEHLK + QEE  KLEE+++ LE EII F K KA SE   +Q 
Sbjct: 361 KEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQ- 419

Query: 435 FLATGSNLRKDKDRK 449
                ++ +KDK RK
Sbjct: 420 ---LSTDTKKDKHRK 431


>gi|149363664 septin 8 isoform d [Homo sapiens]
          Length = 369

 Score =  556 bits (1433), Expect = e-158
 Identities = 277/369 (75%), Positives = 317/369 (85%), Gaps = 1/369 (0%)

Query: 83  IDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPI 142
           ++TLFNT FE  E+SH    V+L+ QTY+LQESNVQLKLTIV+ VGFGDQINK+ESY+PI
Sbjct: 1   MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI 60

Query: 143 VDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVN 202
           VDYIDAQFE YLQEELKI+RSLF YHD+RIHVCLYFI+PTGHSLK+LDL+TMK LDSKVN
Sbjct: 61  VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 120

Query: 203 IIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVV 262
           IIP+IAKADT+SK+EL KFKIK+M ELVSNGVQIYQFPTDD+ +A++NA MN  LPFAVV
Sbjct: 121 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 180

Query: 263 GSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELY 322
           GS +EVKVGNK+V+ARQYPWGVVQVENENHCDFVKLREMLI  NMEDLREQTH+RHYELY
Sbjct: 181 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 240

Query: 323 RRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILK 382
           RRCKLEEMGF D   +++P S+QETYEAKR EF  E QRKEEEM+QMFV +VKE E  LK
Sbjct: 241 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 300

Query: 383 EAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGSN- 441
           E EREL  KFEHLKR+HQEE+ K+EEKRR LEEE  AF+++KA  E   SQ+  AT    
Sbjct: 301 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 360

Query: 442 LRKDKDRKN 450
           LRKDKD+KN
Sbjct: 361 LRKDKDKKN 369


>gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]
          Length = 437

 Score =  309 bits (792), Expect = 3e-84
 Identities = 165/383 (43%), Positives = 246/383 (64%), Gaps = 11/383 (2%)

Query: 43  MSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE----SSH 98
           + G+VGF +LP+Q+  +S+++GF F ++ VGE+G+GKSTLI++LF T+    E    S  
Sbjct: 27  LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 86

Query: 99  FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEEL 158
               V+++     ++E  VQL LTIV+T GFGD ++    +QP++DYID++FE YL  E 
Sbjct: 87  IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 146

Query: 159 KIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTEL 218
           ++ R      D+R+  CLYFI+P+GH LK LD+  MK L  KVNIIP+IAKADT++  E 
Sbjct: 147 RVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 204

Query: 219 QKFKIKLMSELVSNGVQIYQFP-TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
           Q+FK ++M E+  + ++IY+FP TDD+   K+   +  +LP AVVGS   ++V  K V+ 
Sbjct: 205 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 264

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGP 337
           RQYPWGV +VEN  HCDF  LR MLI T+M+DL++ T+  HYE YR  KL  + +  V  
Sbjct: 265 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 324

Query: 338 ENKPVSVQET----YEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFE 393
                 + ++     E +R E   + ++ E EM+Q+F  +VKEK   LK++E ELQ + E
Sbjct: 325 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 384

Query: 394 HLKRLHQEERMKLEEKRRLLEEE 416
            +K+  + +  +LEEKRR  E+E
Sbjct: 385 QMKKNLEAQHKELEEKRRQFEDE 407


>gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]
          Length = 436

 Score =  309 bits (792), Expect = 3e-84
 Identities = 165/383 (43%), Positives = 246/383 (64%), Gaps = 11/383 (2%)

Query: 43  MSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE----SSH 98
           + G+VGF +LP+Q+  +S+++GF F ++ VGE+G+GKSTLI++LF T+    E    S  
Sbjct: 26  LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 85

Query: 99  FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEEL 158
               V+++     ++E  VQL LTIV+T GFGD ++    +QP++DYID++FE YL  E 
Sbjct: 86  IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145

Query: 159 KIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTEL 218
           ++ R      D+R+  CLYFI+P+GH LK LD+  MK L  KVNIIP+IAKADT++  E 
Sbjct: 146 RVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 203

Query: 219 QKFKIKLMSELVSNGVQIYQFP-TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
           Q+FK ++M E+  + ++IY+FP TDD+   K+   +  +LP AVVGS   ++V  K V+ 
Sbjct: 204 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 263

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGP 337
           RQYPWGV +VEN  HCDF  LR MLI T+M+DL++ T+  HYE YR  KL  + +  V  
Sbjct: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323

Query: 338 ENKPVSVQET----YEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFE 393
                 + ++     E +R E   + ++ E EM+Q+F  +VKEK   LK++E ELQ + E
Sbjct: 324 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 383

Query: 394 HLKRLHQEERMKLEEKRRLLEEE 416
            +K+  + +  +LEEKRR  E+E
Sbjct: 384 QMKKNLEAQHKELEEKRRQFEDE 406


>gi|156602655 septin 3 isoform A [Homo sapiens]
          Length = 358

 Score =  254 bits (649), Expect = 1e-67
 Identities = 130/295 (44%), Positives = 195/295 (66%), Gaps = 9/295 (3%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESS-----HF 99
           G++G +++ +Q+  ++++ GF FNI+ VG++G+GKSTL++TLF +      SS       
Sbjct: 40  GYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKI 99

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              V++KA  + ++E  V++KLT+++T GFGDQIN E  ++PI  YI+ Q+E +L+EE+ 
Sbjct: 100 PKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVN 159

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFISPTGHSL+ LDL  MK+L   VNIIPVIAKADT++  E  
Sbjct: 160 IARKK-RIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKS 218

Query: 220 KFKIKLMSELVSNGVQIY---QFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVK 276
           +FK ++  EL  NG++ Y   +F  D +   + +      +PFAVVGS  E +V  K V 
Sbjct: 219 EFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVL 278

Query: 277 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMG 331
            R+ PWG+++VEN NHC+F  LR+ +I T+++DL+E TH  HYE YR  +L + G
Sbjct: 279 GRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNG 333


>gi|156602653 septin 3 isoform B [Homo sapiens]
          Length = 350

 Score =  254 bits (649), Expect = 1e-67
 Identities = 130/295 (44%), Positives = 195/295 (66%), Gaps = 9/295 (3%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESS-----HF 99
           G++G +++ +Q+  ++++ GF FNI+ VG++G+GKSTL++TLF +      SS       
Sbjct: 40  GYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKI 99

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              V++KA  + ++E  V++KLT+++T GFGDQIN E  ++PI  YI+ Q+E +L+EE+ 
Sbjct: 100 PKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVN 159

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFISPTGHSL+ LDL  MK+L   VNIIPVIAKADT++  E  
Sbjct: 160 IARKK-RIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKS 218

Query: 220 KFKIKLMSELVSNGVQIY---QFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVK 276
           +FK ++  EL  NG++ Y   +F  D +   + +      +PFAVVGS  E +V  K V 
Sbjct: 219 EFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVL 278

Query: 277 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMG 331
            R+ PWG+++VEN NHC+F  LR+ +I T+++DL+E TH  HYE YR  +L + G
Sbjct: 279 GRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNG 333


>gi|9945439 septin 5 [Homo sapiens]
          Length = 369

 Score =  253 bits (646), Expect = 3e-67
 Identities = 137/347 (39%), Positives = 217/347 (62%), Gaps = 20/347 (5%)

Query: 46  HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 100
           +VGF +LP+Q+  +S+++GF F ++  GE+G+GKSTL+ +LF T+ ++D +         
Sbjct: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83

Query: 101 PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 160
             V++   T +++E  V+LKLTIV+T GFGD +N  E ++PI DY+D QFE Y ++E  +
Sbjct: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143

Query: 161 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 220
            R      D+R+H CLYFISP GH L+ +D+  MK L  KVNI+P+IAKAD +  +E++K
Sbjct: 144 NRK--NIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK 201

Query: 221 FKIKLMSELVSNGVQIYQFPT----DDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVK 276
            K ++  E+   G+ +YQFP     +D+   + +  +    PFAV+GS   V+   + V+
Sbjct: 202 LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVR 261

Query: 277 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEM--GFTD 334
            R YPWG+V+VEN+ HCDFVKLR MLI T+M DL++ T   HYE YR   +++M    T 
Sbjct: 262 GRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQ 321

Query: 335 VGPENKPVSV--QETYEAKRHEFHGERQRKEEEMKQM--FVQRVKEK 377
                 P+ +    T +A+  +     + K+EE+++M   +QR+K++
Sbjct: 322 DSRMESPIPILPLPTPDAETEKL---IRMKDEELRRMQEMLQRMKQQ 365


>gi|4758942 septin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score =  252 bits (643), Expect = 6e-67
 Identities = 129/311 (41%), Positives = 200/311 (64%), Gaps = 11/311 (3%)

Query: 46  HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 100
           +VGF +LP+Q+  +S+++GF F ++  GE+G+GKSTL+++LF T+ + D +         
Sbjct: 124 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 183

Query: 101 PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 160
             V++     +++E  V+L+LTIV+T GFGD +N  E ++P+ +YID QFE Y ++E  +
Sbjct: 184 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 243

Query: 161 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 220
            R      D+R+H CLYFISP GH L+ LD+  MK L  +VNI+P++AKADT++  E+  
Sbjct: 244 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 301

Query: 221 FKIKLMSELVSNGVQIYQFP---TDDDTIAKV-NAAMNGQLPFAVVGSMDEVKVGNKMVK 276
            K K+  E+   G++IYQFP   +D+D   K+ + A+   +PFAV+GS   V+   + V+
Sbjct: 302 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 361

Query: 277 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVG 336
            R YPWG+V+VEN  HCDFVKLR ML+ T+M+DL++ T   HYE YR   ++ M    V 
Sbjct: 362 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVK 421

Query: 337 PENKPVSVQET 347
             N+    +E+
Sbjct: 422 ERNRNKLTRES 432


>gi|17986247 septin 4 isoform 3 [Homo sapiens]
          Length = 459

 Score =  252 bits (643), Expect = 6e-67
 Identities = 129/311 (41%), Positives = 200/311 (64%), Gaps = 11/311 (3%)

Query: 46  HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 100
           +VGF +LP+Q+  +S+++GF F ++  GE+G+GKSTL+++LF T+ + D +         
Sbjct: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164

Query: 101 PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 160
             V++     +++E  V+L+LTIV+T GFGD +N  E ++P+ +YID QFE Y ++E  +
Sbjct: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224

Query: 161 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 220
            R      D+R+H CLYFISP GH L+ LD+  MK L  +VNI+P++AKADT++  E+  
Sbjct: 225 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 282

Query: 221 FKIKLMSELVSNGVQIYQFP---TDDDTIAKV-NAAMNGQLPFAVVGSMDEVKVGNKMVK 276
            K K+  E+   G++IYQFP   +D+D   K+ + A+   +PFAV+GS   V+   + V+
Sbjct: 283 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 342

Query: 277 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVG 336
            R YPWG+V+VEN  HCDFVKLR ML+ T+M+DL++ T   HYE YR   ++ M    V 
Sbjct: 343 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVK 402

Query: 337 PENKPVSVQET 347
             N+    +E+
Sbjct: 403 ERNRNKLTRES 413


>gi|164698504 septin 9 isoform f [Homo sapiens]
          Length = 335

 Score =  247 bits (630), Expect = 2e-65
 Identities = 125/292 (42%), Positives = 195/292 (66%), Gaps = 8/292 (2%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNF-----EDYESSHF 99
           G+VG +S+ +Q+  ++++QGF FNI+ VG++G+GKSTLI+TLF +       +       
Sbjct: 26  GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 85

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              +++K+ T++++E  V++KLT+++T GFGD IN E  +QPI+ +I+ Q+E YLQEE+ 
Sbjct: 86  PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 145

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFI  TGHSL+ LD+  MK L   VNI+PVIAKADT++  E  
Sbjct: 146 INRKK-RIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 204

Query: 220 KFKIKLMSELVSNGVQIY-QFPTDDDTIAK-VNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
            FK ++ ++L+SNG+ +Y Q   D+D+  + VN      +PFAVVGS  E +V  K +  
Sbjct: 205 HFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILG 264

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEE 329
           R+  WG ++VEN  HC+F  LR++LI T+M+++++ T + H+E YR  +L E
Sbjct: 265 RKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE 316


>gi|164698502 septin 9 isoform d [Homo sapiens]
          Length = 474

 Score =  247 bits (630), Expect = 2e-65
 Identities = 125/292 (42%), Positives = 195/292 (66%), Gaps = 8/292 (2%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNF-----EDYESSHF 99
           G+VG +S+ +Q+  ++++QGF FNI+ VG++G+GKSTLI+TLF +       +       
Sbjct: 165 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 224

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              +++K+ T++++E  V++KLT+++T GFGD IN E  +QPI+ +I+ Q+E YLQEE+ 
Sbjct: 225 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 284

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFI  TGHSL+ LD+  MK L   VNI+PVIAKADT++  E  
Sbjct: 285 INRKK-RIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 343

Query: 220 KFKIKLMSELVSNGVQIY-QFPTDDDTIAK-VNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
            FK ++ ++L+SNG+ +Y Q   D+D+  + VN      +PFAVVGS  E +V  K +  
Sbjct: 344 HFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILG 403

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEE 329
           R+  WG ++VEN  HC+F  LR++LI T+M+++++ T + H+E YR  +L E
Sbjct: 404 RKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE 455


>gi|164698500 septin 9 isoform e [Homo sapiens]
          Length = 422

 Score =  247 bits (630), Expect = 2e-65
 Identities = 125/292 (42%), Positives = 195/292 (66%), Gaps = 8/292 (2%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNF-----EDYESSHF 99
           G+VG +S+ +Q+  ++++QGF FNI+ VG++G+GKSTLI+TLF +       +       
Sbjct: 113 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 172

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              +++K+ T++++E  V++KLT+++T GFGD IN E  +QPI+ +I+ Q+E YLQEE+ 
Sbjct: 173 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 232

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFI  TGHSL+ LD+  MK L   VNI+PVIAKADT++  E  
Sbjct: 233 INRKK-RIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 291

Query: 220 KFKIKLMSELVSNGVQIY-QFPTDDDTIAK-VNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
            FK ++ ++L+SNG+ +Y Q   D+D+  + VN      +PFAVVGS  E +V  K +  
Sbjct: 292 HFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILG 351

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEE 329
           R+  WG ++VEN  HC+F  LR++LI T+M+++++ T + H+E YR  +L E
Sbjct: 352 RKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE 403


>gi|164698498 septin 9 isoform b [Homo sapiens]
          Length = 579

 Score =  247 bits (630), Expect = 2e-65
 Identities = 125/292 (42%), Positives = 195/292 (66%), Gaps = 8/292 (2%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNF-----EDYESSHF 99
           G+VG +S+ +Q+  ++++QGF FNI+ VG++G+GKSTLI+TLF +       +       
Sbjct: 270 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 329

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              +++K+ T++++E  V++KLT+++T GFGD IN E  +QPI+ +I+ Q+E YLQEE+ 
Sbjct: 330 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 389

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFI  TGHSL+ LD+  MK L   VNI+PVIAKADT++  E  
Sbjct: 390 INRKK-RIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 448

Query: 220 KFKIKLMSELVSNGVQIY-QFPTDDDTIAK-VNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
            FK ++ ++L+SNG+ +Y Q   D+D+  + VN      +PFAVVGS  E +V  K +  
Sbjct: 449 HFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILG 508

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEE 329
           R+  WG ++VEN  HC+F  LR++LI T+M+++++ T + H+E YR  +L E
Sbjct: 509 RKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE 560


>gi|164698496 septin 9 isoform e [Homo sapiens]
          Length = 422

 Score =  247 bits (630), Expect = 2e-65
 Identities = 125/292 (42%), Positives = 195/292 (66%), Gaps = 8/292 (2%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNF-----EDYESSHF 99
           G+VG +S+ +Q+  ++++QGF FNI+ VG++G+GKSTLI+TLF +       +       
Sbjct: 113 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 172

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              +++K+ T++++E  V++KLT+++T GFGD IN E  +QPI+ +I+ Q+E YLQEE+ 
Sbjct: 173 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 232

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFI  TGHSL+ LD+  MK L   VNI+PVIAKADT++  E  
Sbjct: 233 INRKK-RIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 291

Query: 220 KFKIKLMSELVSNGVQIY-QFPTDDDTIAK-VNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
            FK ++ ++L+SNG+ +Y Q   D+D+  + VN      +PFAVVGS  E +V  K +  
Sbjct: 292 HFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILG 351

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEE 329
           R+  WG ++VEN  HC+F  LR++LI T+M+++++ T + H+E YR  +L E
Sbjct: 352 RKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE 403


>gi|164698494 septin 9 isoform a [Homo sapiens]
          Length = 586

 Score =  247 bits (630), Expect = 2e-65
 Identities = 125/292 (42%), Positives = 195/292 (66%), Gaps = 8/292 (2%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNF-----EDYESSHF 99
           G+VG +S+ +Q+  ++++QGF FNI+ VG++G+GKSTLI+TLF +       +       
Sbjct: 277 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 336

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              +++K+ T++++E  V++KLT+++T GFGD IN E  +QPI+ +I+ Q+E YLQEE+ 
Sbjct: 337 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 396

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFI  TGHSL+ LD+  MK L   VNI+PVIAKADT++  E  
Sbjct: 397 INRKK-RIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 455

Query: 220 KFKIKLMSELVSNGVQIY-QFPTDDDTIAK-VNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
            FK ++ ++L+SNG+ +Y Q   D+D+  + VN      +PFAVVGS  E +V  K +  
Sbjct: 456 HFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILG 515

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEE 329
           R+  WG ++VEN  HC+F  LR++LI T+M+++++ T + H+E YR  +L E
Sbjct: 516 RKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE 567


>gi|116256489 septin 9 isoform c [Homo sapiens]
          Length = 568

 Score =  247 bits (630), Expect = 2e-65
 Identities = 125/292 (42%), Positives = 195/292 (66%), Gaps = 8/292 (2%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNF-----EDYESSHF 99
           G+VG +S+ +Q+  ++++QGF FNI+ VG++G+GKSTLI+TLF +       +       
Sbjct: 259 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 318

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              +++K+ T++++E  V++KLT+++T GFGD IN E  +QPI+ +I+ Q+E YLQEE+ 
Sbjct: 319 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 378

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           I R      D+R+H CLYFI  TGHSL+ LD+  MK L   VNI+PVIAKADT++  E  
Sbjct: 379 INRKK-RIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 437

Query: 220 KFKIKLMSELVSNGVQIY-QFPTDDDTIAK-VNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
            FK ++ ++L+SNG+ +Y Q   D+D+  + VN      +PFAVVGS  E +V  K +  
Sbjct: 438 HFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILG 497

Query: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEE 329
           R+  WG ++VEN  HC+F  LR++LI T+M+++++ T + H+E YR  +L E
Sbjct: 498 RKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE 549


>gi|56549640 septin 2 [Homo sapiens]
          Length = 361

 Score =  245 bits (625), Expect = 7e-65
 Identities = 139/372 (37%), Positives = 217/372 (58%), Gaps = 48/372 (12%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE-----SSHF 99
           G+VGF +LP+Q+  +S+++GF F ++ VGE+G+GKSTLI++LF T+          +   
Sbjct: 16  GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKI 75

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              V+++A T E++E  V+L+LT+V+T G+GD IN  + ++ I+ YID QFE YL +E  
Sbjct: 76  ERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESG 135

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           + R      D+R+H C YFISP GH LK LD+  MK + +KVNI+PVIAKADT++  E +
Sbjct: 136 LNRRHII--DNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERE 193

Query: 220 KFKIKLMSELVSNGVQIYQFP----TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           + K +++ E+  + ++IY  P     +D+   +    +   +PF+VVGS   ++   K V
Sbjct: 194 RLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKV 253

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           + R YPWGVV+VEN  H DF+KLR MLI T+M+DL+E T   HYE +R  +L+       
Sbjct: 254 RGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLK------- 305

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
                                G R+ + E+M          K+ IL E E EL+   E +
Sbjct: 306 --------------------RGGRKVENEDM---------NKDQILLEKEAELRRMQEMI 336

Query: 396 KRLHQEERMKLE 407
            R+  + +M+++
Sbjct: 337 ARMQAQMQMQMQ 348


>gi|56549638 septin 2 [Homo sapiens]
          Length = 361

 Score =  245 bits (625), Expect = 7e-65
 Identities = 139/372 (37%), Positives = 217/372 (58%), Gaps = 48/372 (12%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE-----SSHF 99
           G+VGF +LP+Q+  +S+++GF F ++ VGE+G+GKSTLI++LF T+          +   
Sbjct: 16  GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKI 75

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              V+++A T E++E  V+L+LT+V+T G+GD IN  + ++ I+ YID QFE YL +E  
Sbjct: 76  ERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESG 135

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           + R      D+R+H C YFISP GH LK LD+  MK + +KVNI+PVIAKADT++  E +
Sbjct: 136 LNRRHII--DNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERE 193

Query: 220 KFKIKLMSELVSNGVQIYQFP----TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           + K +++ E+  + ++IY  P     +D+   +    +   +PF+VVGS   ++   K V
Sbjct: 194 RLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKV 253

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           + R YPWGVV+VEN  H DF+KLR MLI T+M+DL+E T   HYE +R  +L+       
Sbjct: 254 RGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLK------- 305

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
                                G R+ + E+M          K+ IL E E EL+   E +
Sbjct: 306 --------------------RGGRKVENEDM---------NKDQILLEKEAELRRMQEMI 336

Query: 396 KRLHQEERMKLE 407
            R+  + +M+++
Sbjct: 337 ARMQAQMQMQMQ 348


>gi|56549636 septin 2 [Homo sapiens]
          Length = 361

 Score =  245 bits (625), Expect = 7e-65
 Identities = 139/372 (37%), Positives = 217/372 (58%), Gaps = 48/372 (12%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE-----SSHF 99
           G+VGF +LP+Q+  +S+++GF F ++ VGE+G+GKSTLI++LF T+          +   
Sbjct: 16  GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKI 75

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              V+++A T E++E  V+L+LT+V+T G+GD IN  + ++ I+ YID QFE YL +E  
Sbjct: 76  ERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESG 135

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           + R      D+R+H C YFISP GH LK LD+  MK + +KVNI+PVIAKADT++  E +
Sbjct: 136 LNRRHII--DNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERE 193

Query: 220 KFKIKLMSELVSNGVQIYQFP----TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           + K +++ E+  + ++IY  P     +D+   +    +   +PF+VVGS   ++   K V
Sbjct: 194 RLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKV 253

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           + R YPWGVV+VEN  H DF+KLR MLI T+M+DL+E T   HYE +R  +L+       
Sbjct: 254 RGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLK------- 305

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
                                G R+ + E+M          K+ IL E E EL+   E +
Sbjct: 306 --------------------RGGRKVENEDM---------NKDQILLEKEAELRRMQEMI 336

Query: 396 KRLHQEERMKLE 407
            R+  + +M+++
Sbjct: 337 ARMQAQMQMQMQ 348


>gi|4758158 septin 2 [Homo sapiens]
          Length = 361

 Score =  245 bits (625), Expect = 7e-65
 Identities = 139/372 (37%), Positives = 217/372 (58%), Gaps = 48/372 (12%)

Query: 45  GHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE-----SSHF 99
           G+VGF +LP+Q+  +S+++GF F ++ VGE+G+GKSTLI++LF T+          +   
Sbjct: 16  GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKI 75

Query: 100 CPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELK 159
              V+++A T E++E  V+L+LT+V+T G+GD IN  + ++ I+ YID QFE YL +E  
Sbjct: 76  ERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESG 135

Query: 160 IKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQ 219
           + R      D+R+H C YFISP GH LK LD+  MK + +KVNI+PVIAKADT++  E +
Sbjct: 136 LNRRHII--DNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERE 193

Query: 220 KFKIKLMSELVSNGVQIYQFP----TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMV 275
           + K +++ E+  + ++IY  P     +D+   +    +   +PF+VVGS   ++   K V
Sbjct: 194 RLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKV 253

Query: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDV 335
           + R YPWGVV+VEN  H DF+KLR MLI T+M+DL+E T   HYE +R  +L+       
Sbjct: 254 RGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLK------- 305

Query: 336 GPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHL 395
                                G R+ + E+M          K+ IL E E EL+   E +
Sbjct: 306 --------------------RGGRKVENEDM---------NKDQILLEKEAELRRMQEMI 336

Query: 396 KRLHQEERMKLE 407
            R+  + +M+++
Sbjct: 337 ARMQAQMQMQMQ 348


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,504,925
Number of Sequences: 37866
Number of extensions: 689141
Number of successful extensions: 8630
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 225
Number of HSP's successfully gapped in prelim test: 459
Number of HSP's that attempted gapping in prelim test: 4783
Number of HSP's gapped (non-prelim): 2791
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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