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Search of human proteins with 218777837
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218777837 abhydrolase domain containing 7 [Homo sapiens]
(362 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218777837 abhydrolase domain containing 7 [Homo sapiens] 766 0.0
gi|218777840 abhydrolase domain containing 9 [Homo sapiens] 327 1e-89
gi|13376164 abhydrolase domain containing 9 [Homo sapiens] 327 1e-89
gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens] 159 5e-39
gi|145611434 abhydrolase domain containing 8 [Homo sapiens] 70 2e-12
gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo sap... 61 2e-09
gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo sap... 61 2e-09
gi|18777795 serine hydrolase-like 2 [Homo sapiens] 53 5e-07
gi|221316588 biphenyl hydrolase-like [Homo sapiens] 49 9e-06
gi|31542303 abhydrolase domain containing 5 [Homo sapiens] 47 3e-05
gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo sa... 47 3e-05
gi|29294639 mesoderm specific transcript isoform a [Homo sapiens] 47 3e-05
gi|29294637 mesoderm specific transcript isoform b [Homo sapiens] 47 3e-05
gi|29294635 mesoderm specific transcript isoform b [Homo sapiens] 47 3e-05
gi|50658087 abhydrolase domain containing 4 [Homo sapiens] 46 5e-05
gi|189027141 abhydrolase domain containing 6 [Homo sapiens] 45 1e-04
gi|7706645 protein phosphatase methylesterase 1 [Homo sapiens] 43 4e-04
gi|4503583 epoxide hydrolase 1 [Homo sapiens] 38 0.016
gi|209862837 epoxide hydrolase 1 [Homo sapiens] 38 0.016
gi|8923001 abhydrolase domain containing 10 [Homo sapiens] 31 1.5
gi|32528310 abhydrolase domain containing 12B isoform c [Homo sa... 31 1.5
gi|13376042 dermal papilla derived protein 13 [Homo sapiens] 30 3.4
gi|32451492 abhydrolase domain containing 12B isoform b [Homo sa... 30 3.4
gi|109689718 abhydrolase domain containing 12 isoform a [Homo sa... 30 4.4
gi|24308097 abhydrolase domain containing 12 isoform b [Homo sap... 30 4.4
>gi|218777837 abhydrolase domain containing 7 [Homo sapiens]
Length = 362
Score = 766 bits (1978), Expect = 0.0
Identities = 362/362 (100%), Positives = 362/362 (100%)
Query: 1 MARLRDCLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPP 60
MARLRDCLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPP
Sbjct: 1 MARLRDCLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPP 60
Query: 61 ACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEY 120
ACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEY
Sbjct: 61 ACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEY 120
Query: 121 RVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAI 180
RVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAI
Sbjct: 121 RVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAI 180
Query: 181 CYPEMVMKLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKH 240
CYPEMVMKLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKH
Sbjct: 181 CYPEMVMKLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKH 240
Query: 241 LFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTL 300
LFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTL
Sbjct: 241 LFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTL 300
Query: 301 LLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRK 360
LLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRK
Sbjct: 301 LLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRK 360
Query: 361 KD 362
KD
Sbjct: 361 KD 362
>gi|218777840 abhydrolase domain containing 9 [Homo sapiens]
Length = 360
Score = 327 bits (837), Expect = 1e-89
Identities = 158/348 (45%), Positives = 223/348 (64%), Gaps = 5/348 (1%)
Query: 10 RLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPPACLSDPSLG 69
RL L L WSLV+ + A+++ L + P + R PACLSDPSLG
Sbjct: 14 RLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRRSASPACLSDPSLG 73
Query: 70 THCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRG 129
H ++ +K SGLR HYV+AG PLML LHGFPE W+SWRYQLREF+S + VVA+DLRG
Sbjct: 74 EHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRG 133
Query: 130 YGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKL 189
YG +DAP Y +D L+ DIKD++ LGYSKC+L+ HDWG ++AW +I YP +V ++
Sbjct: 134 YGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERM 193
Query: 190 IVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTGI 249
+V++ +V+ +Y L H +Q +S Y + FQ+PW PE + S++DF++LK T TGI
Sbjct: 194 VVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTTLTHRKTGI 253
Query: 250 GRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAF 309
C LT +LEA++Y FSQPG L+GP+N+YRN+F PL+ +TTPTLLLWGE D +
Sbjct: 254 ---PC-LTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTY 309
Query: 310 MEVEMAE-VTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKE 356
+E+ + E + +V IL HW+ Q P +++ +W FL++
Sbjct: 310 LELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQD 357
>gi|13376164 abhydrolase domain containing 9 [Homo sapiens]
Length = 360
Score = 327 bits (837), Expect = 1e-89
Identities = 158/348 (45%), Positives = 223/348 (64%), Gaps = 5/348 (1%)
Query: 10 RLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPPACLSDPSLG 69
RL L L WSLV+ + A+++ L + P + R PACLSDPSLG
Sbjct: 14 RLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRRSASPACLSDPSLG 73
Query: 70 THCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRG 129
H ++ +K SGLR HYV+AG PLML LHGFPE W+SWRYQLREF+S + VVA+DLRG
Sbjct: 74 EHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRG 133
Query: 130 YGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKL 189
YG +DAP Y +D L+ DIKD++ LGYSKC+L+ HDWG ++AW +I YP +V ++
Sbjct: 134 YGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERM 193
Query: 190 IVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTGI 249
+V++ +V+ +Y L H +Q +S Y + FQ+PW PE + S++DF++LK T TGI
Sbjct: 194 VVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTTLTHRKTGI 253
Query: 250 GRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAF 309
C LT +LEA++Y FSQPG L+GP+N+YRN+F PL+ +TTPTLLLWGE D +
Sbjct: 254 ---PC-LTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTY 309
Query: 310 MEVEMAE-VTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKE 356
+E+ + E + +V IL HW+ Q P +++ +W FL++
Sbjct: 310 LELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQD 357
>gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 159 bits (401), Expect = 5e-39
Identities = 105/334 (31%), Positives = 170/334 (50%), Gaps = 48/334 (14%)
Query: 59 PPACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREF-K 117
P +C +PS +H YV +K +R H+V G P + L HGFPE WYSWRYQ+ +
Sbjct: 229 PTSC--NPSDMSHGYVTVKPR-VRLHFVELGSG--PAVCLCHGFPESWYSWRYQIPALAQ 283
Query: 118 SEYRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWL 177
+ YRV+A+D++GYGE+ AP + Y ++ L ++ LD LG S+ V IGHDWGGM+ W
Sbjct: 284 AGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWY 343
Query: 178 IAICYPEMVMKLIVINFP----HPNVFTEYILRHPAQLLKSS----YYYFFQIPWFPEFM 229
+A+ YPE V + +N P +PN+ P + +K++ Y +FQ P E
Sbjct: 344 MALFYPERVRAVASLNTPFIPANPNM-------SPLESIKANPVFDYQLYFQEPGVAEAE 396
Query: 230 FSINDFKVLKHLFTSHSTGI--GRKGCQ-----------------LTTEDLEAYIYVFSQ 270
N + K LF + + K C+ +T E+++ Y+ F +
Sbjct: 397 LEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKK 456
Query: 271 PGALSGPINHYRNI-----FSCLPLKHHMVTTPTLLLWGENDAFMEVEMAEVTKIYVKNY 325
G GP+N YRN+ ++C L + P L++ E D + +M++ + ++ +
Sbjct: 457 SG-FRGPLNWYRNMERNWKWACKSL-GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHL 514
Query: 326 FRLTILSEASHWLQQDQPDIVNKLIWTFLKEETR 359
R I + HW Q D+P VN+++ +L + R
Sbjct: 515 KRGHI-EDCGHWTQMDKPTEVNQILIKWLDSDAR 547
>gi|145611434 abhydrolase domain containing 8 [Homo sapiens]
Length = 439
Score = 70.5 bits (171), Expect = 2e-12
Identities = 75/272 (27%), Positives = 112/272 (41%), Gaps = 32/272 (11%)
Query: 89 GERGKPLMLLLHGFPEFWYSWRYQLREF-KSEYRVVALDLRGYGETDAPIHRQNYKLDCL 147
G + ++ +HG W+ QL F + Y VVA DL G+G + AP Y L
Sbjct: 171 GAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYAL 230
Query: 148 ITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINFPHPNVFTEYILRH 207
D++ I + VLIGH +G +A YP++V K+I+IN P
Sbjct: 231 AEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTA-------- 282
Query: 208 PAQLLKSSYYYFFQIPWFPEFMFS-INDFKVLKHLFTSHSTGIGRKGCQLTTEDLEAYIY 266
L+ S+ F +P S + LK F G K QL E +
Sbjct: 283 ----LEPSFCSIFNMPTCVLHCLSPCLAWSFLKAGFARQ----GAKEKQLLKEGNAFNVS 334
Query: 267 VFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAFMEVE----MAEVTKIYV 322
F +SG + + H +T P LL+ G +D F+ VE MAE+ +
Sbjct: 335 SFVLRAMMSGQYWPEGD-----EVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAF 389
Query: 323 KNYFRLTILSEASHWLQQDQPDIVNKLIWTFL 354
L ++ E SH + + P+ VN L+ FL
Sbjct: 390 -----LKLIDEGSHMVMLECPETVNTLLHEFL 416
>gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo
sapiens]
Length = 315
Score = 60.8 bits (146), Expect = 2e-09
Identities = 61/264 (23%), Positives = 112/264 (42%), Gaps = 31/264 (11%)
Query: 89 GERGKPLMLLLHGF--PEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDC 146
GE P ++ LHG + ++ ++ ++ RV+ +D R +G D+P H + +
Sbjct: 62 GEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSP-HSPDMSYEI 118
Query: 147 LITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINF-----PHPNVFT 201
+ D++D+L LG CV++GH GG A L+A+ PE+V +LI ++ + F
Sbjct: 119 MSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFA 178
Query: 202 EYILRHPAQLLKSSYYYFFQIPWFPEFMFS-INDFKVLKHLFTSHSTGIGRKGCQLTTED 260
Y+ A + E + S I D V +HL T+ GR ++ +
Sbjct: 179 TYVAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDA 238
Query: 261 LEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAFME-VEMAEVTK 319
L ++ + P + PTL L G N F+ E+ +
Sbjct: 239 LTQHL-----------------DKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMR 281
Query: 320 IYVKNYFRLTILSEASHWLQQDQP 343
++ + ++ + A HW+ D+P
Sbjct: 282 LFPR--AQMQTVPNAGHWIHADRP 303
>gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo
sapiens]
Length = 308
Score = 60.8 bits (146), Expect = 2e-09
Identities = 61/264 (23%), Positives = 112/264 (42%), Gaps = 31/264 (11%)
Query: 89 GERGKPLMLLLHGF--PEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDC 146
GE P ++ LHG + ++ ++ ++ RV+ +D R +G D+P H + +
Sbjct: 55 GEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSP-HSPDMSYEI 111
Query: 147 LITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINF-----PHPNVFT 201
+ D++D+L LG CV++GH GG A L+A+ PE+V +LI ++ + F
Sbjct: 112 MSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFA 171
Query: 202 EYILRHPAQLLKSSYYYFFQIPWFPEFMFS-INDFKVLKHLFTSHSTGIGRKGCQLTTED 260
Y+ A + E + S I D V +HL T+ GR ++ +
Sbjct: 172 TYVAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDA 231
Query: 261 LEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAFME-VEMAEVTK 319
L ++ + P + PTL L G N F+ E+ +
Sbjct: 232 LTQHL-----------------DKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMR 274
Query: 320 IYVKNYFRLTILSEASHWLQQDQP 343
++ + ++ + A HW+ D+P
Sbjct: 275 LFPR--AQMQTVPNAGHWIHADRP 296
>gi|18777795 serine hydrolase-like 2 [Homo sapiens]
Length = 314
Score = 52.8 bits (125), Expect = 5e-07
Identities = 29/109 (26%), Positives = 59/109 (54%)
Query: 87 AAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDC 146
A G P +L LHG+ + S+ + ++ VA+D G+G + Y L
Sbjct: 26 AWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQT 85
Query: 147 LITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINFP 195
+++I+ ++ +L +++ ++GH +GG++ + +PEMV KLI+++ P
Sbjct: 86 FVSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTP 134
>gi|221316588 biphenyl hydrolase-like [Homo sapiens]
Length = 291
Score = 48.5 bits (114), Expect = 9e-06
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 6/121 (4%)
Query: 75 RIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREF-KSEYRVVALDLRGYGET 133
++ +G++ HY GE ++LL + QL+ K + VVA D RGYG +
Sbjct: 43 KVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHS 102
Query: 134 DAPIHRQNYKLDCLITDIKDILD---SLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLI 190
P +++ D D KD +D +L + K L+G GG+ A + A YP + K++
Sbjct: 103 RPP--DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV 160
Query: 191 V 191
+
Sbjct: 161 I 161
>gi|31542303 abhydrolase domain containing 5 [Homo sapiens]
Length = 349
Score = 47.0 bits (110), Expect = 3e-05
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 93 KPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKL--DCLITD 150
K ++LLHGF W + + V A DL G+G + P + + + +
Sbjct: 75 KTPLVLLHGFGGGLGLWALNFGDLCTNRPVYAFDLLGFGRSSRPRFDSDAEEVENQFVES 134
Query: 151 IKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVI 192
I++ +LG K +L+GH+ GG +A ++ YP V LI++
Sbjct: 135 IEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILV 176
>gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo
sapiens]
Length = 258
Score = 47.0 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 89 GERGKPLMLLLHGF--PEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDC 146
GE P ++ LHG + ++ ++ ++ RV+ +D R +G D+P H + +
Sbjct: 62 GEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSP-HSPDMSYEI 118
Query: 147 LITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAI 180
+ D++D+L LG CV++GH GG A L+A+
Sbjct: 119 MSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLAL 152
>gi|29294639 mesoderm specific transcript isoform a [Homo sapiens]
Length = 335
Score = 47.0 bits (110), Expect = 3e-05
Identities = 35/102 (34%), Positives = 57/102 (55%), Gaps = 8/102 (7%)
Query: 80 GLRFHYV-AAGERGKP-LMLLLHGFPEFWYSWRYQLREFKS--EYRVVALDLRGYGETDA 135
GLR Y + G G P +++LLHGFP Y W Y++ E + +RV+ALD G+G +D
Sbjct: 54 GLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDW-YKIWEGLTLRFHRVIALDFLGFGFSDK 112
Query: 136 PIHRQNYKLDCLITDIKDILDSLGYS--KCVLIGHDWGGMIA 175
P +Y + + ++ +L LG + L+ HD+G ++A
Sbjct: 113 P-RPHHYSIFEQASIVEALLRHLGLQNRRINLLSHDYGDIVA 153
>gi|29294637 mesoderm specific transcript isoform b [Homo sapiens]
Length = 326
Score = 47.0 bits (110), Expect = 3e-05
Identities = 35/102 (34%), Positives = 57/102 (55%), Gaps = 8/102 (7%)
Query: 80 GLRFHYV-AAGERGKP-LMLLLHGFPEFWYSWRYQLREFKS--EYRVVALDLRGYGETDA 135
GLR Y + G G P +++LLHGFP Y W Y++ E + +RV+ALD G+G +D
Sbjct: 45 GLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDW-YKIWEGLTLRFHRVIALDFLGFGFSDK 103
Query: 136 PIHRQNYKLDCLITDIKDILDSLGYS--KCVLIGHDWGGMIA 175
P +Y + + ++ +L LG + L+ HD+G ++A
Sbjct: 104 P-RPHHYSIFEQASIVEALLRHLGLQNRRINLLSHDYGDIVA 144
>gi|29294635 mesoderm specific transcript isoform b [Homo sapiens]
Length = 326
Score = 47.0 bits (110), Expect = 3e-05
Identities = 35/102 (34%), Positives = 57/102 (55%), Gaps = 8/102 (7%)
Query: 80 GLRFHYV-AAGERGKP-LMLLLHGFPEFWYSWRYQLREFKS--EYRVVALDLRGYGETDA 135
GLR Y + G G P +++LLHGFP Y W Y++ E + +RV+ALD G+G +D
Sbjct: 45 GLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDW-YKIWEGLTLRFHRVIALDFLGFGFSDK 103
Query: 136 PIHRQNYKLDCLITDIKDILDSLGYS--KCVLIGHDWGGMIA 175
P +Y + + ++ +L LG + L+ HD+G ++A
Sbjct: 104 P-RPHHYSIFEQASIVEALLRHLGLQNRRINLLSHDYGDIVA 144
>gi|50658087 abhydrolase domain containing 4 [Homo sapiens]
Length = 342
Score = 46.2 bits (108), Expect = 5e-05
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 86 VAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYK-- 143
V+ + + ++++HGF W + + + DL G+G + P ++ +
Sbjct: 61 VSPEQNDRTPLVMVHGFGGGVGLWILNMDSLSARRTLHTFDLLGFGRSSRPAFPRDPEGA 120
Query: 144 LDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVIN 193
D +T I+ +++G +L+GH GG +A +I YP+ V LI+++
Sbjct: 121 EDEFVTSIETWRETMGIPSMILLGHSLGGFLATSYSIKYPDRVKHLILVD 170
>gi|189027141 abhydrolase domain containing 6 [Homo sapiens]
Length = 337
Score = 44.7 bits (104), Expect = 1e-04
Identities = 73/304 (24%), Positives = 120/304 (39%), Gaps = 53/304 (17%)
Query: 73 YVRIKDSGLRFHYVAAGERG-KPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGY- 130
YV +D +F Y G G KP +L+LHGF W ++ +V +D+ G+
Sbjct: 52 YVHHED--YQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHE 109
Query: 131 GETDAPIHRQNYKLDCLITDIKDILDSLGYSK--CVLIGHDWGGMIAWLIAICYPEMVMK 188
G T + + + +D + I ++ L +K L+G GG +A + A YP V
Sbjct: 110 GTTRSSL--DDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSS 167
Query: 189 LIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTG 248
L ++ PA L S+ F Q K L+
Sbjct: 168 LCLV--------------CPAGLQYSTDNQFVQ------------RLKELQGSAAVEKIP 201
Query: 249 IGRKGCQLTTEDLEAYIYV-FSQP-GALSGPI-------NHYRNIF-------SCLPLKH 292
+ + +E L+ YV F P L G + N YR +F S L
Sbjct: 202 LIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNNFYRKLFLEIVSEKSRYSLHQ 261
Query: 293 HM--VTTPTLLLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLI 350
+M + PT ++WG+ D ++V A++ + N ++ +L H + ++P KLI
Sbjct: 262 NMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIAN-CQVELLENCGHSVVMERPRKTAKLI 320
Query: 351 WTFL 354
FL
Sbjct: 321 IDFL 324
>gi|7706645 protein phosphatase methylesterase 1 [Homo sapiens]
Length = 386
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 9/99 (9%)
Query: 83 FHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKS--EYRVVALDLRGYGETDAPIHRQ 140
F +G G P++LLLHG SW S + R+VALDLR +GET + +
Sbjct: 67 FRVYKSGSEG-PVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVK-NPE 124
Query: 141 NYKLDCLITDIKDILDSLGYS----KCVLIGHDWGGMIA 175
+ + + D+ ++++++ Y +LIGH GG IA
Sbjct: 125 DLSAETMAKDVGNVVEAM-YGDLPPPIMLIGHSMGGAIA 162
>gi|4503583 epoxide hydrolase 1 [Homo sapiens]
Length = 455
Score = 37.7 bits (86), Expect = 0.016
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 27/151 (17%)
Query: 68 LGTHCYVRIKDSGLRFHYV-------AAGERGKPLMLLLHGFPEFWYSWRYQLREFKSE- 119
L + + + K GL H++ AG KPL L++HG+P +Y + Y++ ++
Sbjct: 110 LNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPL-LMVHGWPGSFYEF-YKIIPLLTDP 167
Query: 120 ----------YRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHD 169
+ V+ + GYG ++A ++ + ++ LG+ + + G D
Sbjct: 168 KNHGLSDEHVFEVICPSIPGYGFSEAS-SKKGFNSVATARIFYKLMLRLGFQEFYIQGGD 226
Query: 170 WGGMIAWLIAICYPEMV------MKLIVINF 194
WG +I +A P V M L++ NF
Sbjct: 227 WGSLICTNMAQLVPSHVKGLHLNMALVLSNF 257
>gi|209862837 epoxide hydrolase 1 [Homo sapiens]
Length = 455
Score = 37.7 bits (86), Expect = 0.016
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 27/151 (17%)
Query: 68 LGTHCYVRIKDSGLRFHYV-------AAGERGKPLMLLLHGFPEFWYSWRYQLREFKSE- 119
L + + + K GL H++ AG KPL L++HG+P +Y + Y++ ++
Sbjct: 110 LNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPL-LMVHGWPGSFYEF-YKIIPLLTDP 167
Query: 120 ----------YRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHD 169
+ V+ + GYG ++A ++ + ++ LG+ + + G D
Sbjct: 168 KNHGLSDEHVFEVICPSIPGYGFSEAS-SKKGFNSVATARIFYKLMLRLGFQEFYIQGGD 226
Query: 170 WGGMIAWLIAICYPEMV------MKLIVINF 194
WG +I +A P V M L++ NF
Sbjct: 227 WGSLICTNMAQLVPSHVKGLHLNMALVLSNF 257
>gi|8923001 abhydrolase domain containing 10 [Homo sapiens]
Length = 306
Score = 31.2 bits (69), Expect = 1.5
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 123 VALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICY 182
+ D G G +D + + L D+ I+D L +L+G GG + AI
Sbjct: 108 IRFDYSGVGSSDG--NSEESTLGKWRKDVLSIIDDLADGPQILVGSSLGGWLMLHAAIAR 165
Query: 183 PEMVMKLIVINFPHPNVFTEY 203
PE V+ LI + + T++
Sbjct: 166 PEKVVALIGVATAADTLVTKF 186
>gi|32528310 abhydrolase domain containing 12B isoform c [Homo
sapiens]
Length = 285
Score = 31.2 bits (69), Expect = 1.5
Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 16/157 (10%)
Query: 53 RPAREHPPACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEF-WYSWRY 111
R R P+C + + G C Y AA G P+++ LHG E S R
Sbjct: 32 RNLRHTVPSCRGEDAKGKDCC----------WYEAALRDGNPIIVYLHGSAEHRAASHRL 81
Query: 112 QLREFKSE--YRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHD 169
+L + S+ + V+++D RG+G++ + D + + G + L GH
Sbjct: 82 KLVKVLSDGGFHVLSVDYRGFGDSTGKPTEEGLTTDAICV-YEWTKARSGITPVCLWGHS 140
Query: 170 WGGMIAWLIAICYPE--MVMKLIVINFPHPNVFTEYI 204
G +A A E + IV+ P N++ I
Sbjct: 141 LGTGVATNAAKVLEEKGCPVDAIVLEAPFTNMWVASI 177
>gi|13376042 dermal papilla derived protein 13 [Homo sapiens]
Length = 434
Score = 30.0 bits (66), Expect = 3.4
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 13/72 (18%)
Query: 264 YIYVFSQPGALSGPINHYRNIFS--------CLPLKHHMVTTPTLLLWG-----ENDAFM 310
++Y+F G GPIN+ +N+F+ L H + P L L G N M
Sbjct: 308 WLYLFEGSGVPYGPINNMKNVFAEPQNAVSGFQSLLHSLAHGPFLHLQGSARVLHNGLVM 367
Query: 311 EVEMAEVTKIYV 322
E+E V KI V
Sbjct: 368 EMEHPTVGKISV 379
>gi|32451492 abhydrolase domain containing 12B isoform b [Homo
sapiens]
Length = 255
Score = 30.0 bits (66), Expect = 3.4
Identities = 36/150 (24%), Positives = 61/150 (40%), Gaps = 16/150 (10%)
Query: 60 PACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEF-WYSWRYQLREFKS 118
P+C + + G C Y AA G P+++ LHG E S R +L + S
Sbjct: 9 PSCRGEDAKGKDCC----------WYEAALRDGNPIIVYLHGSAEHRAASHRLKLVKVLS 58
Query: 119 E--YRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAW 176
+ + V+++D RG+G++ + D + + G + L GH G +A
Sbjct: 59 DGGFHVLSVDYRGFGDSTGKPTEEGLTTDAICV-YEWTKARSGITPVCLWGHSLGTGVAT 117
Query: 177 LIAICYPE--MVMKLIVINFPHPNVFTEYI 204
A E + IV+ P N++ I
Sbjct: 118 NAAKVLEEKGCPVDAIVLEAPFTNMWVASI 147
>gi|109689718 abhydrolase domain containing 12 isoform a [Homo
sapiens]
Length = 398
Score = 29.6 bits (65), Expect = 4.4
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 12/138 (8%)
Query: 94 PLMLLLHGFPEF-WYSWRYQLREFKSE--YRVVALDLRGYGETDAPIHRQNYKLDCLITD 150
P++L LHG R +L + S Y VV D RG+G++ + D L
Sbjct: 169 PIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDAL--H 226
Query: 151 IKDILDSLGYSKCVLI-GHDWGGMIAWLIA--ICYPEMVMKLIVINFPHPNVFTEYILRH 207
+ D + + V I GH G +A + +C E +++ P N+ E H
Sbjct: 227 VFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNI-REEAKSH 285
Query: 208 PAQLLKSSYYYFFQIPWF 225
P ++ Y YF WF
Sbjct: 286 PFSVI---YRYFPGFDWF 300
>gi|24308097 abhydrolase domain containing 12 isoform b [Homo
sapiens]
Length = 404
Score = 29.6 bits (65), Expect = 4.4
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 12/138 (8%)
Query: 94 PLMLLLHGFPEF-WYSWRYQLREFKSE--YRVVALDLRGYGETDAPIHRQNYKLDCLITD 150
P++L LHG R +L + S Y VV D RG+G++ + D L
Sbjct: 169 PIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDAL--H 226
Query: 151 IKDILDSLGYSKCVLI-GHDWGGMIAWLIA--ICYPEMVMKLIVINFPHPNVFTEYILRH 207
+ D + + V I GH G +A + +C E +++ P N+ E H
Sbjct: 227 VFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNI-REEAKSH 285
Query: 208 PAQLLKSSYYYFFQIPWF 225
P ++ Y YF WF
Sbjct: 286 PFSVI---YRYFPGFDWF 300
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.142 0.472
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,903,674
Number of Sequences: 37866
Number of extensions: 678253
Number of successful extensions: 1690
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1655
Number of HSP's gapped (non-prelim): 30
length of query: 362
length of database: 18,247,518
effective HSP length: 104
effective length of query: 258
effective length of database: 14,309,454
effective search space: 3691839132
effective search space used: 3691839132
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.